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Charlson age comorbidity index

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https://www.readbyqxmd.com/read/29788022/hospitalizations-in-children-with-a-penicillin-allergy-label-an-assessment-of-healthcare-impact
#1
Bernardo Sousa-Pinto, Luís Araújo, Alberto Freitas, Luís Delgado
BACKGROUND: Beta-lactam allergy is overdiagnosed. Diagnosis of penicillin allergy has been associated with a greater use of hospital resources and an increased risk of antibiotic-resistant infections, although this issue remains poorly studied in children. We aimed to compare patient characteristics and use of hospital resources in hospitalized children with and without a record of penicillin allergy. METHODS: We identified all hospitalizations in children labelled as being allergic to penicillin in a database containing all hospitalizations in Portuguese public hospitals between 2000 and 2014, and compared these with a similar number of age-, sex-, and main diagnosis-matched hospitalizations without a penicillin allergy label...
May 22, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29787368/contemporary-surgical-outcomes-of-venous-tumour-thrombectomy-managed-with-intraoperative-doppler-ultrasound-for-kidney-cancer
#2
Deepak K Pruthi, Hanzhang Wang, Arpan Satsangi, Miguel Cajipe, Kevan Iffrig, Georges M Haidar, Taylor Hicks, Edward Y Sako, Michael A Liss, Wasim H Chowdhury, Ronald Rodriguez, Dharam Kaushik
INTRODUCTION: Radical nephrectomy (RN) with venous tumour thrombectomy (VTT) carries a significant morbidity and mortality risk. Examination of a contemporary single-institution series permits the development of a management algorithm and an audit its results. We report outcomes following the use of intraoperative colour Doppler ultrasound and our surgical pathway. METHODS: We retrospectively reviewed the records of all patients who underwent RN with VTT for kidney cancer between January 1, 2013 and October 1, 2016...
May 14, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29785449/parkinson-s-disease-increases-the-risk-of-perioperative-complications-after-total-knee-arthroplasty-a-nationwide-database-study
#3
Jared M Newman, Nipun Sodhi, Alyeesha B Wilhelm, Anton Khlopas, Alison K Klika, Qais Naziri, Thomas J Kryzak, Carlos A Higuera, Michael A Mont
PURPOSE: Therefore, the purpose of this study was to evaluate the short-term perioperative outcomes of PD patients who underwent total knee arthroplasty (TKA). We specifically evaluated: (1) perioperative surgical and medical complications; (2) lengths of stay (LOS); and (3) total hospital charges. METHODS: The Nationwide Inpatient Sample was used to identify PD patients who underwent TKA between 2002 and 2013. To control for potential confounders, PD TKA and non-PD TKA patients were propensity score matched (1:3) based on age, sex, ethnicity, Charlson Comorbidity Index, and insurance type...
May 21, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29784546/complexity-of-the-medication-regimen-for-polypathological-patients
#4
L Bellostas-Muñoz, J Díez-Manglano
OBJECTIVE: To determine the complexity of the therapeutic regimen for polypathological patients hospitalised in internal medicine departments. METHODS: A multicentre observational study included polypathological patients hospitalised in internal medicine departments. Patients who were readmitted or died were excluded. Data were collected on age, sex, residence, disease, Charlson, Barthel and Lawton-Brody indices, Pfeiffer questionnaire, Gijón scale, number of hospitalisations in the previous year, delirium, need for and availability of caregivers and the PROFUND index score...
May 18, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29783959/soluble-urokinase-plasminogen-activator-receptor-predicts-mortality-in-exacerbated-copd
#5
Nina S Godtfredsen, Ditte V Jørgensen, Kristoffer Marsaa, Charlotte S Ulrik, Ove Andersen, Jesper Eugen-Olsen, Line J H Rasmussen
BACKGROUND: The inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is elevated in severe acute and chronic medical conditions and has been associated with short-term mortality. The role of suPAR in predicting risk of death following an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has never been studied. We hypothesized that increased suPAR is an independent predictor of short-term mortality in patients admitted to hospital with COPD or acute respiratory failure...
May 21, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29783749/differential-impact-of-malnutrition-on-health-outcomes-among-indigenous-and-non-indigenous-adults-admitted-to-hospital-in-regional-australia-a-prospective-cohort-study
#6
Natasha Morris, Simon Stewart, Malcolm Riley, Graeme Maguire
The burden of malnutrition in Indigenous people is a major health priority and this study's aims are to understand health outcomes among Indigenous and non-Indigenous patients. This cohort study includes 608 medical inpatients in three regional hospitals. Participants were screened for malnutrition using the Subjective Global Assessment tool. Hospital length of stay, discharge destination, 30-day and six-month hospital readmission and survival were measured. Although no significant difference was observed between Indigenous participants who were malnourished or nourished ( p = 0...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29778788/maintaining-dose-intensity-of-adjuvant-chemotherapy-in-older-patients-with-breast-cancer
#7
Rahul Ladwa, Timothy Kalas, Shivanshan Pathmanathan, Natasha Woodward, David Wyld, Jasotha Sanmugarajah
INTRODUCTION: Maintaining the relative dose intensity (RDI) of adjuvant chemotherapy at ≥ 85% has been associated with improved treatment outcomes in early-stage breast cancer (ESBC). Increasing evidence has suggested that patients aged ≥ 65 years can maintain the optimal RDI for standard chemotherapy regimens. The present study investigated the RDI of newer adjuvant chemotherapy regimens in this demographic. PATIENTS AND METHODS: We retrospectively analyzed the data from 281 patients aged ≥ 65 years with a diagnosis of ESBC who had received adjuvant chemotherapy across 3 sites in Queensland, Australia from 2010 to 2015...
April 28, 2018: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29777842/nationally-representative-readmission-factors-in-patients-with-claudication-and-critical-limb-ischemia
#8
Rennier A Martinez, Michelle Shnayder, Joshua Parreco, Lukas Gaffney, Marcus Eby, Nicholas Cortolillo, Michael Lopez, Jack Zeltzer
INTRODUCTION: Hospital readmissions are not only associated with increased mortality, morbidity and costs but also, with current healthcare reform, tied to significant financial and administrative penalties. Some studies show that patients undergoing vascular surgery may have higher than average readmission rates. The recently released Nationwide Readmission Database (NRD) is the most comprehensive national source of readmission data, gathering discharge information from 22 geographically dispersed states, accounting for 51...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29777350/the-american-association-for-the-surgery-of-trauma-emergency-general-surgery-anatomic-severity-scoring-system-as-a-predictor-of-cost-in-appendicitis
#9
Eric J Finnesgard, Matthew C Hernandez, Johnathon M Aho, Martin D Zielinski
BACKGROUND: The World Society for Emergency Surgery determined that for appendicitis managed with appendectomy, there is a paucity of evidence evaluating costs with respect to disease severity. The American Association for the Surgery of Trauma (AAST) disease severity grading system is valid and generalizable for appendicitis. We aimed to evaluate hospitalization costs incurred by patients with increasing disease severity as defined by the AAST. We hypothesized that increasing disease severity would be associated with greater cost...
May 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29777150/risk-factors-of-treatment-failure-and-30-day-mortality-in-patients-with-bacteremia-due-to-mrsa-with-reduced-vancomycin-susceptibility
#10
Chien-Chang Yang, Cheng-Len Sy, Yhu-Chering Huang, Shian-Sen Shie, Jwu-Ching Shu, Pang-Hsin Hsieh, Ching-Hsi Hsiao, Chih-Jung Chen
Bacteremia caused by MRSA with reduced vancomycin susceptibility (MRSA-RVS) frequently resulted in treatment failure and mortality. The relation of bacterial factors and unfavorable outcomes remains controversial. We retrospectively reviewed clinical data of patients with bacteremia caused by MRSA with vancomycin MIC = 2 mg/L from 2009 to 2012. The significance of bacterial genotypes, agr function and heterogeneous vancomycin-intermediate S. aureus (hIVSA) phenotype in predicting outcomes were determined after clinical covariates adjustment with multivariate analysis...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776419/introduction-of-national-guidelines-for-restrictive-blood-transfusion-threshold-for-hip-fracture-patients-a-consecutive-cohort-study-based-on-complete-follow-up-in-national-databases
#11
Bjarke Viberg, Per Hviid Gundtoft, Jesper Schønnemann, Lasse Pedersen, Lis Røhl Andersen, Kjell Titlestad, Carsten Fladmose Madsen, Jens Lauritsen, Søren Overgaard
BACKGROUND: Randomized controlled trials have demonstrated that a restrictive red blood cell (RBC) transfusion strategy lowers transfusion frequency without affecting mortality. However, the external validity of these trials has not been tested in a large cohort. The purpose was to estimate the effect of introducing a National Clinical Guideline (NCG) for a restrictive hemoglobin transfusion threshold on transfusion frequency and mortality in hip fracture patients > 65 years old...
May 18, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29770238/charlson-comorbidity-index-as-a-predictor-of-periodontal-disease-in-elderly-participants
#12
Jae-Hong Lee, Jung-Kyu Choi, Seong-Nyum Jeong, Seong-Ho Choi
Purpose: This study investigated the validity of the Charlson comorbidity index (CCI) as a predictor of periodontal disease (PD) over a 12-year period. Methods: Nationwide representative samples of 149,785 adults aged ≥60 years with PD (International Classification of Disease, 10th revision [ICD-10], K052-K056) were derived from the National Health Insurance Service-Elderly Cohort during 2002-2013. The degree of comorbidity was measured using the CCI (grade 0-6), including 17 diseases weighted on the basis of their association with mortality, and data were analyzed using multivariate Cox proportional-hazards regression in order to investigate the associations of comorbid diseases (CDs) with PD...
April 2018: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/29769074/delay-in-reviewing-test-results-prolongs-hospital-length-of-stay-a-retrospective-cohort-study
#13
Mei-Sing Ong, Farah Magrabi, Enrico Coiera
BACKGROUND: Failure in the timely follow-up of test results has been widely documented, contributing to delayed medical care. Yet, the impact of delay in reviewing test results on hospital length of stay (LOS) has not been studied. We examine the relationship between laboratory tests review time and hospital LOS. METHODS: A retrospective cohort study of inpatients admitted to a metropolitan teaching hospital in Sydney, Australia, between 2011 and 2012 (n = 5804)...
May 16, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29766216/impact-of-angiotensin-converting-enzyme-inhibitors-or-receptor-blockers-on-post-icu-discharge-outcome-in-patients-with-acute-kidney-injury
#14
Etienne Gayat, Alexa Hollinger, Alain Cariou, Nicolas Deye, Antoine Vieillard-Baron, Samir Jaber, Benjamin G Chousterman, Qin Lu, Pierre François Laterre, Xavier Monnet, Michael Darmon, Marc Leone, Bertrand Guidet, Romain Sonneville, Jean-Yves Lefrant, Marie-Céline Fournier, Matthieu Resche-Rigon, Alexandre Mebazaa, Matthieu Legrand
PURPOSE: Acute kidney injury (AKI) is associated with the activation of the renin-angiotensin system. Whether angiotensin-converting enzyme inhibitors (ACEi) or angiotensin-receptor blockers (ARB) improve outcome in patients recovering from AKI remains unexplored. The purpose was to investigate the association between prescription of ACEi/ARB at intensive care unit (ICU) discharge and 1-year outcome in patients recovering from AKI. METHODS: Association between ACEi/ARB and 1-year mortality rate was explored in 1551 patients discharged from 21 European ICUs in an observational cohort...
May 15, 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/29761843/calf-circumference-a-marker-of-muscle-mass-as-a-predictor-of-hospital-readmission
#15
Gustavo Gonzales Real, Inara Regina Frühauf, José Henrique Koth Sedrez, Eduarda Jaine Fachinello Dall'Aqua, Maria Cristina Gonzalez
Hospital readmissions (HRs) are common, potentially preventable, and a marker of poor quality in health services. This study aimed to identify risk factors for HR in clinical patients, with an emphasis on nutrition aspects, especially calf circumference (CC), as a marker of muscle mass. A prospective cohort study of patients admitted to the internal medicine ward was conducted. The short form of the Patient-Generated Subjective Global Assessment was performed in the first 24 hours of hospitalization. In addition, single-frequency bioelectrical impedance analysis was used to estimate the phase angle, CC as a surrogate of muscle mass, and handgrip strength as a marker of strength...
May 15, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29760963/effectiveness-of-a-day-rehabilitation-program-in-improving-functional-outcome-and-reducing-mortality-and-readmission-of-elderly-patients-with-fragility-hip-fractures
#16
Tak Man Wong, Frankie K L Leung, Tak Wing Lau, Christian Fang, Felix H W Chan, Jun Wu
Introduction: The incidence of hip fracture is projected to increase in the next 25 years as the world population ages. Hip fracture is often associated with subsequent readmission and mortality. Nevertheless, elderly patients often may not achieve the same level of functional ability as prior to their injury. Several studies have shown that close collaboration between orthopedic surgeons and geriatricians can improve such outcomes and Geriatric Day Hospital (GDH) is one of the examples of collaboration to improve such outcomes...
2018: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29760606/influence-of-major-coping-strategies-on-treatment-non-adherence-and-severity-of-comorbid-conditions-in-hemodialysis-patients
#17
Hyun Chan Hwang, Hye Ri Kim, Doug Hyun Han, Ji Sun Hong, So-Hee Jeong, Jung-Ho Shin, Su-Hyun Kim, Jin Ho Hwang, Sun Mi Kim
Background: Non-adherence and comorbidities are prevalent among hemodialysis patients and are associated with increased mortality and financial burden. We aimed to investigate the influence of major coping strategies (CSs) on non-adherence and comorbidities in hemodialysis patients. Methods: A total of 49 patients were enrolled. We collected participant data including CS measured by a Korean version of the ways of coping questionnaire (K-WCQ), comorbidities measured by age-adjusted Charlson comorbidity index (CCI), and adherence measured by the 8-item Morisky medication adherence scale (MMAS-8)...
May 14, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29756457/descriptive-analysis-of-associated-factors-for-urgent-versus-nonurgent-inpatient-spine-transfers-to-a-tertiary-care-hospital
#18
Gregory D Schroeder, James C McKenzie, David S Casper, Seth Stake, Joseph Buchholz, Chris Kepler, Jeffery A Rihn, Barret I Woods, Kris E Radcliff, I David Kaye, Kristen Nicholson, D Greg Anderson, Alan S Hilibrand, Alexander R Vaccaro, Safdar Khan, Mark F Kurd
Patients with spine-associated symptoms are transferred regularly to higher levels of care for operative intervention. It is unclear what factors lead to the transfer of patients with spine pathology to level I care facilities, and which transfers are indicated. All patients with isolated spinal pathology who were transferred from 2011 to 2015 were reviewed. Patients were divided into urgent transfers, defined as anyone who required operative intervention, and nonurgent transfers. Two hundred twenty-seven patients were transferred for isolated spinal pathology over 51 months; 109 (48...
May 1, 2018: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/29756307/age-adjusted-comorbidity-and-survival-in-locally-advanced-laryngeal-cancer
#19
Collin F Mulcahy, Abdallah S R Mohamed, Aasheesh Kanwar, Katherine A Hutcheson, Alokananda Ghosh, David Vock, Randal S Weber, Stephen Y Lai, Gary Brandon Gunn, Mark Zafereo, William H Morrison, Renata Ferrarotto, Adam S Garden, David I Rosenthal, Clifton D Fuller
BACKGROUND: The purpose of this study was to quantify the relationship among age, pretreatment comorbidity, and survival outcomes in patients with locally advanced laryngeal cancer. METHODS: Baseline comorbidity data were collected and age-adjusted Charlson Comorbidity Index (CCI) was calculated for each case. Kaplan-Meier and Cox proportional hazards modeling were used to determine associations with survival. RESULTS: For 548 patients, with a median age of 59 years (range 31-91 years), 58% were treated with larynx preservation and the rest with total laryngectomy and adjuvant radiotherapy (RT)...
May 13, 2018: Head & Neck
https://www.readbyqxmd.com/read/29755765/travel-distance-and-use-of-salvage-palliative-chemotherapy-in-patients-with-metastatic-colorectal-cancer
#20
Shahid Ahmed, Mahjabeen Iqbal, Duc Le, Nayyer Iqbal, Punam Pahwa
Background: Salvage palliative chemotherapy in metastatic colorectal cancer has been associated with significant improvement in survival. However, not all patients receive all available therapies. Travel burden can affect patient access and use of future therapy. The present study aims to determine relationship between travel distance (TD) and salvage palliative chemotherapy in patients with metastatic colorectal cancer. Method: A patient cohort diagnosed with metastatic colorectal cancer during 2006-2010 in the province of Saskatchewan, Canada was studied...
April 2018: Journal of Gastrointestinal Oncology
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