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Healthy life

Juliana Chaves Ruiz Guedes, Karen de Almeida Pinto Fernandes da Cunha, Jorge Ricardo da Silva Machado, Luciana Wernersbach Pinto
Extranodal NK/T-cell lymphoma nasal type is a rare disease that mainly affects the nasal cavity and paranasal sinuses of males in the fifth decade of life. It has aggressive and locally destructive behaviour, and can be complicated by the hemophagocytic syndrome, conferring high lethality to the disease. This article describes a case of NK/T-cell lymphoma nasal type in a previously healthy patient, exemplifying its rapid and fulminant course.
June 2018: Anais Brasileiros de Dermatologia
Maria Alessi, Katalin Szanto, Alexandre Dombrovski
ABSTRACTObjectives:To understand pathways to suicide by investigating the association between personality and suicidal motivations in mid- and late-life attempts. DESIGN: In a two-study approach, we measured different components of suicidal motivations using an existing self-report investigating reasons for suicide and a semi-qualitative assessment of motivational states preceding attempts. SETTING: Inpatient and outpatient psychiatric services in Pittsburgh, PA...
June 20, 2018: International Psychogeriatrics
Yann Quidé, Sarah Cohen-Woods, Nicole O'Reilly, Vaughan J Carr, Bernet M Elzinga, Melissa J Green
OBJECTIVES: Childhood trauma is a common risk factor for adult psychiatric disorders, such as schizophrenia (SZ) and bipolar-I disorder (BD). However, its association with schizotypal personality traits, as well as cognitive and social cognitive abilities, is less well studied in these populations. METHODS: In a cohort of 79 SZ cases, 84 BD cases, and 75 healthy controls (HCs), clinically significant levels of childhood trauma exposure (according to scores on the Childhood Trauma Questionnaire; CTQ) were evident in 54 SZ, 55 BD, and 26 HC individuals...
June 20, 2018: British Journal of Clinical Psychology
Jeffrey G Snodgrass, H J François Dengah Ii, Michael G Lacy, Robert J Else, Evan R Polzer, Jesusa M G Arevalo, Steven W Cole
OBJECTIVES: To combine social genomics with cultural approaches to expand understandings of the somatic health dynamics of online gaming, including in the controversial nosological construct of internet gaming disorder (IGD). METHODS: In blood samples from 56 U.S. gamers, we examined expression of the conserved transcriptional response to adversity (CTRA), a leukocyte gene expression profile activated by chronic stress. We compared positively engaged and problem gamers, as identified by an ethnographically developed measure, the Positive and Negative Gaming Experiences Scale (PNGE-42), and also by a clinically derived IGD scale (IGDS-SF9)...
June 20, 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
Michael D Rawlins
The UK's Life Sciences Strategy provides UK clinical pharmacologists with a unique opportunity to enhance the impact of their discipline on patients and the NHS as well as the pharmaceutical industry. The full benefits of electronic prescribing systems, supported by artificial intelligence, will require clinical pharmacological expertise. Similarly, the Strategy's support for 'healthy ageing' will only be realized if clinical pharmacologists are able to use their expertise in promoting the safe and effective use of medicines in older people...
June 19, 2018: British Journal of Clinical Pharmacology
Francesca Floris, Federica Comitini, GiovanBattista Leoni, Paolo Moi, Maddalena Morittu, Valeria Orecchia, Maria Perra, Maria Paola Pilia, Antonietta Zappu, Maria Rosaria Casini, Raffaella Origa
PURPOSE: The aim of this study has been to evaluate the physical, psychological, and social well-being in a large group of Sardinian adult patients with transfusion-dependent beta-Thalassemia when compared with a group of healthy subjects of the same age and geographical extraction. METHODS: Male or female patients ≥ 18 years of age with Thalassemia major on regular transfusion at Thalassemia Center in Cagliari (Italy) were requested to complete the World Health Organization Quality of life-BREF (WHOQOL-BREF) questionnaire...
June 19, 2018: Quality of Life Research
Fatemeh Rajati, Hosein Ashtarian, Nader Salari, Masood Ghanbari, Zahra Naghibifar, Seyed Younes Hosseini
BACKGROUND: Physically disabled people experience more restrictions in social activities than healthy people, which are associated with lower level of well-being and poor quality of life (QoL). STUDY DESIGN: A cross-sectional study was conducted. METHODS: This study was investigated on among 302 eligible physically disabled people. The predictive role of the demographics and clinical characteristics, anxiety and depression, physical activity, and self-efficacy on the 36-Item Short Form Health Survey (SF-36) was examined...
2018: Journal of Education and Health Promotion
Vina M Goghari, Linette Lawlor-Savage
The idea that individualized, computer-based cognitive training improves cognitive functioning in non-trained domains is highly contested. An understudied area is whether cognitive training improves one's own perception of cognitive and day-to-day functioning. Furthermore, no studies have compared working memory training to programs that train higher-level processes themselves, namely logic and planning, in improving perception of cognitive abilities. We investigated self-reported changes in: (a) cognitive errors relevant to daily life; (b) expectations regarding training; and (c) impact of training on daily life, in healthy older adults who completed working memory training or logic and planning training...
2018: Frontiers in Aging Neuroscience
Iram Irshad, Pegah Varamini
BACKGROUND: Breast cancer is the most frequently diagnosed malignancy in women worldwide. Breast cancer tends to metastasize to bone. Around 70% of the breast cancer patients eventually develop bone metastasis. After the bone invasion, metastatic cells disrupt the balance between osteoblastic and osteoclastic activities, leading to skeletal complications, characterized by pain and pathological fractures and hence worsening the patient's quality of life. Once tumor invades the bone, it is hard to treat it with, the so-far available treatments options (e...
June 19, 2018: Current Pharmaceutical Design
Laura Kivelä, Kalle Kurppa
AIM: Coeliac disease is a common but markedly under-diagnosed condition, which may lead to serious long-term complications if untreated. Both the diagnostic yield and true incidence have significantly increased during the last few decades and it is now one of the most common chronic gastrointestinal conditions in children. The aim of this review was to summarise the current concepts on screening for coeliac disease in children and adolescents. METHOD: We conducted a non-systematic literature review of papers published about coeliac disease screening since the year 2000...
June 19, 2018: Acta Paediatrica
Teagan Farrugia, Alana Hewitt, Helen Bourke-Taylor, Annette V Joosten
BACKGROUND/AIM: Occupational therapists frequently work with carers and their family member who requires direct services. In Australia, women provide the majority of informal care. Carer status is determined by the provision of informal help or supervision to an older person, or a person with a disability or long-term health condition. Caregiving responsibilities can impact mental and physical health and reduce women's participation in leisure activities and the labour force. The aim of the study was to examine differences in the participation of Australian women, aged 50 years and over, with and without caregiving responsibilities, in self-selected health promoting activities, self-reported mental health and participation in physical activity...
June 19, 2018: Australian Occupational Therapy Journal
Ashraful Kabir, Shahgahan Miah, Asraful Islam
BACKGROUND: Over the past decades, Bangladesh has made substantial progress in improving higher education, and in part, this was achieved by promoting residence based higher education in public universities. University residency is considered a crucial period for students to develop healthy eating habits and adopt nutritious intake, which comprise a strong foundation for good health throughout life. Although, there is extensive literature on eating behaviors and dietary intake internationally, there appears to be relatively scarce research and analysis concerning Bangladesh...
2018: PloS One
Dominik Schaack, Benedikt Hermann Siegler, Sandra Tamulyte, Markus Alexander Weigand, Florian Uhle
BACKGROUND: Sepsis is defined as a life-threatening condition, resulting from a dysregulated and harmful response of the hosts' immune system to infection. Apart from this, the (over-)compensating mechanisms counterbalancing the inflammatory response have been proven to render the host susceptible to further infections and increase delayed mortality. Our study aimed to unravel the heterogeneity of immune response in early sepsis and to explain the biology behind it. METHODS: A systematic search of public repositories yielded 949 microarray samples from patients with sepsis of different infectious origin and early after clinical manifestation...
2018: PloS One
Jennifer L Stewart, John J B Allen
This longitudinal pilot study examined whether baseline resting frontal electroencephalographic (EEG) asymmetry correlates with depressive symptoms during the most impaired two-week period in the following year. Current-source-density (CSD) transformed resting frontal EEG asymmetry, severity of depression symptoms (Beck Depression Inventory - II), and stress (indexed by negative life events; NLE) were recorded in never-depressed young adults with no current DSM-IV diagnosis (38 women, 16 men) at baseline. One year later, depression symptoms and NLEs experienced during the interim were assessed...
June 16, 2018: Biological Psychology
T H Johannsen, K M Main, M L Ljubicic, T K Jensen, H R Andersen, M S Andersen, J H Petersen, A-M Andersson, A Juul
CONTEXT: The early activation of the hypothalamic-pituitary-gonadal axis during infancy can be used in the evaluation of infants suspected of disorders of sex development (DSD). However, few data exists on sex-specific reference ranges for these hormones during early life. OBJECTIVE: To evaluate sex-differences in reproductive hormone concentrations in serum from healthy infants in order to define sex-specific cut-off values and to apply these in infants with DSD...
June 15, 2018: Journal of Clinical Endocrinology and Metabolism
Renata T C Yokota, Willma J Nusselder, Jean-Marie Robine, Jean Tafforeau, Françoise Renard, Patrick Deboosere, Herman Van Oyen
Background: We aimed to investigate the contribution of chronic conditions to gender differences in disability-free life expectancy (DFLE) and life expectancy with disability (LED) in Belgium in 2001, 2004 and 2008. Methods: Data on disability and chronic conditions from participants of the 2001, 2004 and 2008 Health Interview Surveys in Belgium were used to estimate disability prevalence by cause using the attribution method. Disability prevalence was applied to life tables to estimate DFLE and LED using the Sullivan method...
June 15, 2018: European Journal of Public Health
James R Berstock, Andrew D Beswick, José A López-López, Michael R Whitehouse, Ashley W Blom
BACKGROUND: The capacity for total knee arthroplasty to improve pain, quality of life, and functional outcomes is widely recognized. Postoperative mortality is rare but of paramount importance, and needs to be accurately quantified and conveyed to patients in order to support decision-making prior to surgery. The purpose of this study was to determine a contemporary estimate of the risk of mortality following total knee arthroplasty, including the identification of temporal trends, common causes, and modifiable and nonmodifiable risk factors...
June 20, 2018: Journal of Bone and Joint Surgery. American Volume
Giuseppe La Torre, Sergio Guastamacchia, Alfio Barbagallo, Alice Mannocci
OBJECTIVES: Smoking prevalence among health care workers is higher in comparison with general population and the prevalence of women who smoke is higher than among men. In the prevention strategies the multimedia campaign may be a positive impact on the fight against tobacco. Objective. The aim of the study was to assess the impact of the last Italian campaign against smoking (Il fumo fammale) in the health care women workers. METHODS: A cross-sectional study was conducted in Latium and Sicily (Italy) in 2015, through an interview on memories and impressions about the spots and after a new vision of the spot and eventually other comments...
November 2017: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
Holly Gwyther, Elzbieta Bobrowicz Campos, João Apóstolo, Maura Marcucci, Antonio Cano, Carol Holland
Interventions to minimise, reverse or prevent the progression of frailty in older adults represent a potentially viable route to improving quality of life and care needs in older adults. Intervention methods used across European Innovation Partnership on Active and Healthy Ageing (EIP-AHA) collaborators were analysed, along with findings from literature reviews to determine "what works for whom in what circumstances". A realist review of FOCUS study literature reviews, 'real world' studies and grey literature was conducted according to RAMESES standards, and used to populate a framework analysis of theories of why frailty interventions worked, and theories of why frailty interventions did not work...
June 19, 2018: Health Psychology Review
Noman Lateef, Mustafa Dawood, Karn Sharma, Abubakar Tauseef, Muhammad Asadullah Munir, Erin Godbout
Spontaneous pneumothorax in pregnancy is a rare and life-threatening condition. In this report, a case of spontaneous pneumothorax occurring at 34 weeks' gestation in a healthy 34-year-old primigravida is described. She had typical complaints of chest pain and dyspnoea and diagnosis was made by chest X-ray which showed an extensive pneumothorax in the right side. Pneumothorax recurred twice over approximately three weeks. A caesarean section secondary to small pelvic parameters was scheduled with the chest tube in situ and a healthy 2...
2018: Journal of Community Hospital Internal Medicine Perspectives
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