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Rupture aortic aneurysm

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https://www.readbyqxmd.com/read/29147166/a-cost-utility-analysis-of-endovascular-aneurysm-repair-for-abdominal-aortic-aneurysm
#1
Yutaka Takayama
Objective: To assess medical economic adequacy of endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA). Methods: Cost-utility analysis. A total of 21 patients with AAA treated at Ibaraki Prefectural Central Hospital in 2014 were divided into non-ruptured EVAR (Group E) and open surgery (OS) (Group O), and ruptured OS (Group R) groups, and hospital costs were aggregated with a medical accounting system. Mid-level hospital costs were estimated by a diagnosis-procedure-combination analysis system...
September 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29145894/inositol-in-the-management-of-abdominal-aortic-aneurysm-imagen-study-protocol-for-a-randomised-controlled-trial
#2
Sophie E Rowbotham, Jenna L Pinchbeck, Georgina Anderson, Bernie Bourke, Michael Bourke, T Christian Gasser, Rene Jaeggi, Jason S Jenkins, Corey S Moran, Susan K Morton, Christopher M Reid, Ramesh Velu, Lisan Yip, Joseph V Moxon, Jonathan Golledge
BACKGROUND: An abdominal aortic aneurysm (AAA) is a focal dilation of the abdominal aorta and is associated with a risk of fatal rupture. Experimental studies suggest that myo-inositol may exert beneficial effects on AAAs through favourable changes to biological pathways implicated in AAA pathology. The aim of the Inositol in the MAnaGemENt of abdominal aortic aneurysm (IMAGEN) trial is to assess if myo-inositol will reduce AAA growth. METHODS/DESIGN: IMAGEN is a multi-centre, prospective, parallel-group, randomised, double-blind, placebo-controlled trial...
November 16, 2017: Trials
https://www.readbyqxmd.com/read/29141859/unique-pattern-of-aortic-regurgitation-caused-by-rupture-into-the-left-ventricular-interleaflet-triangle-of-a-sinus-valsalva-aneurysm-involving-the-left-coronary-cusp
#3
Yasuhide Mochizuki, Kazuhiko Iwahashi, Keitaro Nakagiri, Junya Shite
No abstract text is available yet for this article.
November 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29141786/intraluminal-thrombus-is-associated-with-early-rupture-of-abdominal-aortic-aneurysm
#4
Stephen J Haller, Jeffrey D Crawford, Katherine M Courchaine, Colin J Bohannan, Gregory J Landry, Gregory L Moneta, Amir F Azarbal, Sandra Rugonyi
BACKGROUND: The implications of intraluminal thrombus (ILT) in abdominal aortic aneurysm (AAA) are currently unclear. Previous studies have demonstrated that ILT provides a biomechanical advantage by decreasing wall stress, whereas other studies have associated ILT with aortic wall weakening. It is further unclear why some aneurysms rupture at much smaller diameters than others. In this study, we sought to explore the association between ILT and risk of AAA rupture, particularly in small aneurysms...
November 12, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29141546/current-theories-and-clinical-trial-evidence-for-limiting-human-abdominal-aortic-aneurysm-growth
#5
Jing Yu, Shuai Liu, Jianhua Huang, Wei Wang
BACKGROUND: Abdominal aortic aneurysm (AAA) refers to localized dilation of abdominal aorta. AAA is largely asymptomatic, but aneurysmal rupture results in a high mortality rate. AAA with a diameter greater than 55 mm carries a high risk of rupture. There are currently no known medical treatments effective in limiting the growth of small AAA. OBJECTIVE: To review the current status of and challenges faced in limiting AAA growth. METHODS: Data from human investigations and animal model studies were summarized...
November 12, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/29138183/endovascular-or-open-repair-for-ruptured-abdominal-aortic-aneurysm
#6
EDITORIAL
Martin Björck
No abstract text is available yet for this article.
November 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29138135/comparative-clinical-effectiveness-and-cost-effectiveness-of-endovascular-strategy-v-open-repair-for-ruptured-abdominal-aortic-aneurysm-three-year-results-of-the-improve-randomised-trial
#7
(no author information available yet)
Objective To assess the three year clinical outcomes and cost effectiveness of a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair for patients with suspected ruptured abdominal aortic aneurysm.Design Randomised controlled trial.Setting 30 vascular centres (29 in UK, one in Canada), 2009-16.Participants 613 eligible patients (480 men) with a clinical diagnosis of ruptured aneurysm, of whom 502 underwent emergency repair for rupture.Interventions 316 patients were randomised to an endovascular strategy (275 with confirmed rupture) and 297 to open repair (261 with confirmed rupture)...
November 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29136132/aortic-events-and-reoperations-after-elective-arch-surgery-incidence-surgical-strategies-and-outcomes
#8
Maximilian Luehr, Sven Peterss, Andreas Zierer, Davide Pacini, Christian D Etz, Malakh Lal Shrestha, Konstantinos Tsagakis, Bartosz Rylski, Giampiero Esposito, Klaus Kallenbach, Ruggero De Paulis, Paul P Urbanski
OBJECTIVES: The true incidence of aortic events (AEs) and reoperations (REDO) following elective total aortic arch replacement remains unknown. The aim of this study was to review the incidence of AEs and surgical REDO, and its respective outcomes after 1232 elective arch repairs at 11 European aortic centres. METHODS: Retrospective chart review (in the absence of prospective data collection) was performed for statistical analysis. Follow-up was conducted during routine clinical examination or in a telephone interview with patients and/or their respective physicians...
November 9, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29134291/local-distribution-of-collagen-fibers-determines-crack-initiation-site-and-its-propagation-direction-during-aortic-rupture
#9
Shukei Sugita, Takeo Matsumoto
Although elucidation of the mechanism of aortic aneurysm rupture is important, the characteristics of crack initiation and propagation sites remain unknown. To determine the microscopic properties of these sites, the characteristics of local strains and constituents at crack initiation and propagation sites were investigated during biaxial stretching of porcine thoracic aortas (PTAs). PTAs were sliced into approximately 50-[Formula: see text]-thick sections, and the center of the sections was made especially thin using our previously developed technique...
November 13, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/29124128/vascular-deformation-mapping-vdm-of-thoracic-aortic-enlargement-in-aneurysmal-disease-and-dissection
#10
Nicholas S Burris, Benjamin A Hoff, Ella A Kazerooni, Brian D Ross
Thoracic aortic aneurysm is a common and lethal disease that requires regular imaging surveillance to determine timing of surgical repair and prevent major complications such as rupture. Current cross-sectional imaging surveillance techniques, largely based on computed tomography angiography, are focused on measurement of maximal aortic diameter, although this approach is limited to fixed anatomic positions and is prone to significant measurement error. Here we present preliminary results showing the feasibility of a novel technique for assessing change in aortic dimensions, termed vascular deformation mapping (VDM)...
September 2017: Tomography: a Journal for Imaging Research
https://www.readbyqxmd.com/read/29120872/a-rare-case-of-hemopericardium-from-a-ruptured-dissecting-pulmonary-artery-aneurysm-postmortem-computed-tomography-scan-and-autopsy-findings
#11
Rexson Tse, Jack Garland, Yvonne Triggs, Simon Stables
Nontraumatic hemopericardium is a potentially fatal pathology that is most commonly caused by myocardial wall rupture, ruptured aortic dissection, aortic aneurysm rupture, or a neoplastic process. A rare potential cause of hemopericardium is pulmonary artery dissection, with less than 100 reported cases in the literature. Pulmonary artery dissection is associated with pulmonary artery aneurysm, pulmonary artery hypertension, and congenital heart disease. We report a fatal case of nontraumatic hemopericardium caused by a ruptured dissecting pulmonary artery aneurysm in a 16-year-old girl with patent ductus arteriosus...
November 9, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/29119826/comment-to-regarding-diabetes-mellitus-increases-the-risk-of-ruptured-abdominal-aortic-aneurysms
#12
Waldemar Wierzba, Andrzej Sliwczynski, Jaroslaw Pinkas, Arkadiusz Jawien, Waldemar Karnafel
This publication is a commentary on the Letter to the Editor by Juliette Raffort and Fabien Lareyre. This article clarifies a number of concerns about the method of calculating the index of prevalence of ruptured abdominal aortic aneurysms (AAA). The method of qualifying patients for the study and the method of calculating the index of prevalence of ruptured AAA in cohorts of diabetic and non-diabetic patients was presented. Most researchers calculate the Index of Prevalence per 100,000 of the general population...
November 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29117792/mortality-after-elective-and-ruptured-abdominal-aortic-aneurysm-surgical-repair-12-year-single-center-experience-of-estonia
#13
J Lieberg, L-L Pruks, M Kals, K Paapstel, A Aavik, J Kals
BACKGROUND AND AIMS: Abdominal aortic aneurysm is a degenerative vascular pathology with high mortality due to its rupture, which is why timely treatment is crucial. The current single-center retrospective study was undertaken to analyze short- and long-term all-cause mortality after operative treatment of abdominal aortic aneurysm and to examine the factors that influence outcome. MATERIAL AND METHODS: The data of all abdominal aortic aneurysm patients treated with open repair or endovascular aneurysm repair in 2004-2015 were retrospectively retrieved from the clinical database of Tartu University Hospital...
November 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29112945/biomechanical-changes-during-abdominal-aortic-aneurysm-growth
#14
Raoul R F Stevens, Andrii Grytsan, Jacopo Biasetti, Joy Roy, Moritz Lindquist Liljeqvist, T Christian Gasser
The biomechanics-based Abdominal Aortic Aneurysm (AAA) rupture risk assessment has gained considerable scientific and clinical momentum. However, such studies have mainly focused on information at a single time point, and little is known about how AAA properties change over time. Consequently, the present study explored how geometry, wall stress-related and blood flow-related biomechanical properties change during AAA expansion. Four patients with a total of 23 Computed Tomography-Angiography (CT-A) scans at different time points were analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/29111330/imaging-mass-spectroscopy-delineates-the-thinned-and-thickened-walls-of-intracranial-aneurysms
#15
Taichi Ikedo, Manabu Minami, Hiroharu Kataoka, Kosuke Hayashi, Manabu Nagata, Risako Fujikawa, Fumiyoshi Yamazaki, Mitsutoshi Setou, Masayuki Yokode, Susumu Miyamoto
OBJECT: The wall thickness of intracranial aneurysms (IAs) is heterogeneous. Although thinning of the IA wall is thought to contribute to IA rupture, the underlying mechanism remains poorly understood. Recently, imaging mass spectroscopy (IMS) has been used to reveal the distribution of phospholipids in vascular diseases. To investigate the feature of phospholipid composition of IA walls, we conducted IMS in a rat model of experimentally induced IA. MATERIAL AND METHODS: IAs were surgically induced in 7-week-old male rats and analyzed by IMS in negative-ion mode...
October 27, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29103932/incidence-and-prognostic-factors-related-to-major-adverse-cerebrovascular-events-in-patients-with-complex-aortic-diseases-treated-by-the-chimney-technique
#16
Michel J Bosiers, Kenneth Tran, Jason T Lee, Konstantinos P Donas, Frank J Veith, Giovanni Torsello, Felice Pecoraro, Konstantinos Stavroulakis
OBJECTIVE: Endovascular aneurysm repair (EVAR) with the chimney technique (ch-EVAR) has been used for the treatment of aortic aneurysms as an alternative approach to fenestrated endografting or open repair. Nonetheless, the need for an upper extremity arterial access may contribute to a higher risk for periprocedural cerebrovascular events. This study reports on the perioperative cerebral and major adverse cardiac and cerebrovascular events (MACCE) after ch-EVAR. METHODS: The PERICLES registry (PERformance of the chImney technique for the treatment of Complex aortic pathoLogiES) is an international, retrospective multicenter study evaluating the performance of ch-EVAR for the treatment of complex aortic pathologies...
November 2, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29102265/does-elevated-wall-tension-cause-aortic-aneurysm-rupture-investigation-using-a-subject-specific-heterogeneous-model
#17
Timothy K Chung, Erasmo S da Silva, Suresh M L Raghavan
OBJECTIVE: To investigate whether peak wall tension in abdominal aortic aneurysm occurs at the site of rupture to test for a causative relationship. METHODS: Four ruptured and nine unruptured AAA were harvested whole from cadavers, followed by regional measurements of wall thickness, elastic parameters and failure tension. Finite element models were developed with subject-specific load-free AAA morphology and heterogeneous properties interpolated using a geodesic distance weighted approach from the measurements...
October 6, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29101897/estimation-of-in-vivo-mechanical-properties-of-the-aortic-wall-a-multi-resolution-direct-search-approach
#18
Minliang Liu, Liang Liang, Wei Sun
The patient-specific biomechanical analysis of the aorta requires in vivo mechanical properties of individual patients. Existing approaches for estimating in vivo material properties often demand high computational cost and mesh correspondence of the aortic wall between different cardiac phases. In this paper, we propose a novel multi-resolution direct search (MRDS) approach for estimation of the nonlinear, anisotropic constitutive parameters of the aortic wall. Based on the finite element (FE) updating scheme, the MRDS approach consists of the following three steps: (1) representing constitutive parameters with multiple resolutions using principal component analysis (PCA), (2) building links between the discretized PCA spaces at different resolutions, and (3) searching the PCA spaces in a 'coarse to fine' fashion following the links...
October 20, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29100862/association-between-diverticular-disease-and-abdominal-aortic-aneurysms-pooled-analysis-of-two-population-based-screening-cohorts
#19
Anders Mark-Christensen, Jes Sanddal Lindholt, Axel Diederichsen, Flemming Hald Steffensen, Martin Busk, Lars Frost, Grazina Urbonaviciene, Jess Lambrechtsen, Kenneth Egstrup, Søren Laurberg
BACKGROUND: The aetiology of abdominal aortic aneurysms (AAA) is multifactorial, and many risk factors are shared with diverticular disease. It is unknown whether an independent association exists between these conditions. METHODS: Individuals enrolled in two Danish population based randomised AAA screening trials and assigned to cross sectional screening and evaluation of cardiovascular risk factors were identified. Diagnoses of diverticular disease were interrogated from a national patient registry covering the period from 1977 to the screening date...
October 31, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29097044/standard-off-the-shelf-multibranched-thoracoabdominal-endograft-in-urgent-and-elective-patients-with-single-and-staged-procedures-in-a-multicenter-experience
#20
Roberto Silingardi, Stefano Gennai, Nicola Leone, Mauro Gargiulo, Gianluca Faggioli, Piergiorgio Cao, Fabio Verzini, Arnaldo Ippoliti, Nicola Tusini, Carmelo Ricci, Michele Antonello, Roberto Chiesa, Enrico Maria Marone, Nicola Mangialardi, Francesco Speziale, Gian Franco Veraldi, Stefano Bonardelli, Luigi Marcheselli
OBJECTIVE: The objective of this study was to assess immediate and midterm outcomes for urgent/emergent and elective patients with thoracoabdominal aortic aneurysms (TAAAs) treated with the first commercially available "off-the-shelf" multibranched endograft for endovascular aneurysm repair, with a single-step or a staged surgical approach. METHODS: A multicenter, nonrandomized, retrospective study was conducted of TAAA patients grouped by urgent/emergent and elective treatment with multibranched endograft for endovascular aneurysm repair at 13 Italian centers from November 2012 to August 2016...
October 31, 2017: Journal of Vascular Surgery
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