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Rupture aortic aneurysm

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https://www.readbyqxmd.com/read/28329283/left-sinus-of-valsalva-aneurysm-as-a-cause-of-chronic-stable-angina
#1
Alexandre Ponti, Salah D Qanadli, Matthias Kirsch, Maxime Tapponnier
Sinus of Valsalva aneurysms are unusual, particularly when located on the left coronary sinus. They are mainly asymptomatic, however once ruptured, they are associated with high mortality. We present hereinafter an atypical case of a 71-year-old patient with an unruptured left sinus of Valsalva aneurysm causing myocardial ischaemia due to a compressed left main coronary artery. Surgical endoaneurysmorrhaphy was performed; however, a dehiscence of the suture line between the patch and the aortic wall required additional percutaneous implantation of a vascular occluder...
February 27, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28321413/fluid-structure-interaction-in-abdominal-aortic-aneurysm-effect-of-modeling-techniques
#2
Shengmao Lin, Xinwei Han, Yonghua Bi, Siyeong Ju, Linxia Gu
In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics and wall mechanics was compared with its simplified techniques, that is, computational fluid dynamics (CFD) or computational solid stress (CSS) model. Results demonstrated that CFD exhibited relatively smaller vortexes and tends to overestimate the fluid wall shear stress, compared to FSI...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28320001/review-1-time-ultrasonography-screening-reduces-abdominal-aortic-aneurysm-related-mortality-and-rupture
#3
Calvin Hirsch
No abstract text is available yet for this article.
March 21, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28318830/long-term-outcome-of-the-gore-excluder-aaa-endoprosthesis-for-treatment-of-infrarenal-aortic-aneurysms
#4
Claire G Poublon, Suzanne Holewijn, Steven M M van Sterkenburg, Ignace F J Tielliu, Clark J Zeebregts, Michel M P J Reijnen
PURPOSE: To evaluate long-term outcome of GORE EXCLUDER AAA Endoprosthesis (W.L. Gore & Associates, Inc, Flagstaff, Arizona) for elective treatment of infrarenal aortic aneurysms and to evaluate performance of different generations of the device. MATERIALS AND METHODS: A retrospective analysis was performed of 248 patients undergoing elective endovascular aneurysm repair with the GORE EXCLUDER between January 2000 and December 2015 in 2 hospitals. Primary endpoint was reintervention-free survival...
March 15, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28318603/rupture-risk-in-abdominal-aortic-aneurysms-a-realistic-assessment-of-the-explicit-gpu-approach
#5
V Strbac, D M Pierce, B Rodriguez-Vila, J Vander Sloten, N Famaey
Accurate estimation of peak wall stress (PWS) is the crux of biomechanically motivated rupture risk assessment for abdominal aortic aneurysms aimed to improve clinical outcomes. Such assessments often use the finite element (FE) method to obtain PWS, albeit at a high computational cost, motivating simplifications in material or element formulations. These simplifications, while useful, come at a cost of reliability and accuracy. We achieve research-standard accuracy and maintain clinically applicable speeds by using novel computational technologies...
February 27, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28315148/a-case-of-cardiac-tamponade-due-to-an-isolated-abscess-in-the-ascending-aorta-of-a-pregnant-woman-with-a-history-of-intravenous-substance-abuse
#6
Brandy Shattuck, John Livingstone
We describe the case of a 23-year-old white female, 10-12 weeks pregnant, with a history of intravenous drug use and a recently diagnosed pneumonia, who was found deceased in her bed after a night of sleep. Although postmortem serum toxicology tested positive for alprazolam, tetrahydrocannabinol, and morphine, the ultimate cause of death was determined to be cardiac tamponade secondary to an isolated abscess in the ascending aorta. The patient had several risk factors for aortic rupture and cardiac tamponade including intravenous drug use, pneumonia, and pregnancy...
March 17, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28302917/hif1%C3%AE-in-aortic-aneurysms-and-beyond
#7
Tomoki Hashimoto, Victor Rizzo
Abdominal aortic aneurysm (AAA) is a permanent expansion of the vessel wall with a high prevalence in those 65 years of age and older. Aneurysms are prone to dissection and rupture that carry a mortality rate of over 85%. Currently, surgical repair is the only option to treat this disease. The need to intervene prior to these events has set off a flurry of basic studies in an effort to understand the cellular and molecular mechanisms that govern AAA formation, progression and rupture. In the present study, the role of myeloid cells in contributing to AAA development has been confirmed...
April 1, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28296545/the-effects-of-nicotine-administration-on-the-pathophysiology-of-rat-aortic-wall
#8
H Kugo, N Zaima, H Tanaka, T Urano, N Unno, T Moriyama
Abdominal aortic aneurysm (AAA) is the progressive dilation of the abdominal aorta. Nicotine is reported to be associated with the development and rupture of AAA, but the pathological effects of nicotine on normal rat aorta have not been determined. We investigated pathological changes in the aortic wall of rats caused by the administration of nicotine. Nicotine administration weakened the vascular wall, increased gelatinolytic activity and promoted the destruction of elastin and collagen in the rat abdominal aorta...
2017: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/28295517/a-giant-aneurysm-of-noncoronary-sinus-of-valsalva-concomitant-with-aortic-regurgitation-and-mitral-regurgitation
#9
Yi Luo, Zhi Fang, Wei Meng
Aneurysms of the sinus of Valsalva (ASV) are rare, with an incidence ranging from 0.1% to 3.5% of all congenital cardiac defects and a prevalence of 0.009% in an autopsy series.ASVs occur much more frequently in the right coronary sinus of Valsalva. Previous reports, based on necropsy and cardiac surgery findings, estimated that 20% of ASVs are unruptured. Patients with an unruptured ASV may remain asymptomatic for a long period of time until rupture. They may also presented with dyspnea, palpitation, and angina-like chest pain...
March 14, 2017: Echocardiography
https://www.readbyqxmd.com/read/28294669/-visceral-complications-of-the-aortic-dissections-indications-and-technique-of-the-thoracoabdominal-refenestration
#10
Csaba Dzsinich, Jenő Szolnoky, Gábor Vallus, Gábor Darabos, Gabriella Nyiri, Dániel Teknős
Aortic dissection is a life threatening cardiovascular catastrophy. Its incidence estimated to 5-6 cases per 100,000 patients/year. The intimal tear happens at the ascending aorta in Type A, meanwhile at the aortic isthmus in Type B, but entry point may develop anywhere alongside the entire aorta. All types may affect a short aortic segment resulting in a localized false aneurysm, others separate the intimal layer at longer extension down to the visceral segment and far beyond to the femoral arteries. Dissection of orifices of side branches may lead to cerebral, upper extremity, spinal, visceral, renal and lower extremity malperfusion...
March 2017: Magyar Sebészet
https://www.readbyqxmd.com/read/28293008/-successful-emergency-management-of-an-infected-thoracic-aortic-aneurysm-rupture-using-a-pedicled-latissimus-dorsi-flap-after-stent-graft-implantation-report-of-a-case
#11
Susumu Takeuchi, Hiroyuki Tanaka, Yoshiro Hori
We report a case of ruptured mycotic thoracic aortic aneurysm treated with a pedicled latissimus dorsi flap after stent-graft implantation. The patient was a 64-year-old woman with diabetes mellitus that had developed septicemia as a result of pyelonephritis and a perinephric abscess. The patient required emergency stent-graft implantation due to rupture of an infected thoracic aortic aneurysm on hospital day 10. On hospital day 19, the abscess cavity was debrided and irrigated, and a pedicled latissimus dorsi flap was created...
March 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28291779/echocardiographic-diagnosis-of-rare-pathological-patterns-of-sinus-of-valsalva-aneurysm
#12
Yali Yang, Li Zhang, Xinfang Wang, Qing Lü, Lin He, Jing Wang, Bin Wang, Ling Li, Li Yuan, Jinfeng Liu, Shuping Ge, Mingxing Xie
OBJECTIVE: To evaluate the value and improve the diagnostic accuracy of echocardiography in the diagnosis of a sinus of Valsalva aneurysm (SVA) with rare pathological patterns. METHODS: Echocardiographic features and surgical findings from 270 Chinese patients with SVA treated in the last 18 years (1995-2013) at the Union Hospital were compared retrospectively; 22 of 270 cases had rare patterns. RESULTS: The patients with SVA, a rare origin, a rare extending position, or a rare course accounted for 3...
2017: PloS One
https://www.readbyqxmd.com/read/28290181/acute-type-a-aortic-dissection-beyond-the-diameter
#13
Calogera Pisano, Carmela Rita Balistreri, Oreste Fabio Triolo, Vincenzo Argano, Giovanni Ruvolo
Aortic dissection is a life-threatening condition in which early diagnosis, treatment and close follow up are critical for survival. Between 60% and 70% of patients with acute aortic dissection are affected at the ascending aorta, classified as Stanford type A (TAD). Preventive surgery of the aorta in asymptomatic patients on the basis of aortic size alone remains controversial among patient populations without known risk factors for aortic dissection. In fact, many dissection patients do not appear to have markedly dilated aortas at the time of presentation...
November 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28288888/a-novel-modification-of-the-murine-elastase-infusion-model-of-abdominal-aortic-aneurysm-formation
#14
Guohua Hu, Zhihui Dong, Weiguo Fu
OBJECT: To create a novel procedure that will decrease the mortality of experimental animals in the intra-arterial infusion of elastase abdominal aortic aneurysm model. METHODS: Novel models were created by means of direct puncture the infrarenal abdominal aortic aorta, intraluminal elastase in the 1cm segment of abdominal aorta. Femoral artery cannula approach and infusing with elastase was considered as the traditional group, and that infusing with saline solution as the control group...
March 10, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28288886/the-atmospheric-pressure-and-temperature-seem-to-have-no-effect-on-the-incidance-of-rupture-of-abdmonial-aortic-aneurysm-in-a-mid-european-region
#15
Payman Majd, Wael Ahmad, Thomas Luebke, Jan Sigge Brunkwall
BACKGROUND/OBJECTIVE: This study aims to examine the relationship between weather changes (atmospheric pressure and temprature) and incidence of rupture of abdominal aortic aneurysm. METHODS: All patients with ruptured infrarenal abdominal aortic aneurysm (AAA) and who were referred to our institution between August 1998 and August 2015 were prospectively entered into a database out of which a retrospective review of a ruptured AAA was performed. The needed information about the daily atmospheric pressure and air temperature could be extracted from the meteorological unit in Cologne...
March 10, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28288885/patients-with-ruptured-abdominal-aortic-aneurysm-have-become-higher-risk
#16
Anoosha Aslam, Charles M Fisher, Cathy Thoo, Michael L Neale, Shannon D Thomas
BACKGROUND: Independent risk factors such as age, loss of consciousness, elevated serum creatinine, low haemoglobin and ECG evidence of ischemia have previously been shown to predict mortality after ruptured abdominal aortic aneurysm (rAAA). With an ageing Australian population, we sought to determine if patients presenting with rAAA now had more predictive risk factors for mortality, and whether these factors remain predictive of mortality. METHODS: The records of all patients presenting with rAAA between January 1985 to December 1993 (past era, group 1) and January 2007 to December 2011 (modern era, group 2) were retrieved...
March 10, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28288701/abdominal-aortic-aneurysm-and-omega-3-polyunsaturated-fatty-acids-mechanisms-animal-models-and-potential-treatment
#17
REVIEW
Lara T Meital, Shaun L Sandow, Philip C Calder, Fraser D Russell
Abdominal aortic aneurysm (AAA) is an inflammatory disease associated with macrophage accumulation in the adventitia, oxidative stress, medial elastin degradation and aortic dilation. Progression of AAA is linked to increased risk of rupture, which carries a high mortality rate. Drug therapies trialled to date lack efficacy and although aneurysm repair is available for patients with large aneurysm, peri-surgical morbidity and mortality have been widely reported. Recent studies using rodent models of AAA suggest that long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFAs) and their metabolites can moderate inflammation and oxidative stress perpetuated by infiltrating macrophages and intervene in the destruction of medial elastin...
March 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28286188/endovascular-repair-of-internal-mammary-artery-aneurysms-in-two-sisters-with-smad3-mutation
#18
Daiva Nevidomskyte, Sherene Shalhub, Gabriel S Aldea, Peter H Byers, Ulrike Schwarze, Mitzi L Murray, Benjamin Starnes
True aneurysms of the internal mammary artery are rare and have been described in association with vasculitis or connective tissue disorders. Herein we describe two cases of familial internal mammary artery aneurysms in two sisters with SMAD3 mutation. The older sister presented at the age of 54 with an incidental diagnosis of a multilobed right internal mammary artery aneurysm (IMA) and the younger sister presented several years earlier with a ruptured left IMA aneurysm at the age of 49. Both sisters had Debakey type I aortic dissections prior to the IMA aneurysm presentation...
March 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28286185/endovascular-repair-of-concomitant-celiac-and-splenic-artery-aneurysms-using-a-combination-of-coil-embolization-and-an-aortic-cuff-stent-graft
#19
Esther Bae, Trung Duong Vo
Large celiac artery aneurysms are associated with a high rupture and mortality risk. Traditionally, open surgical repair has been the mainstay of treatment. Endovascular alternatives have been increasingly described, ranging from coil embolization to exclusion with covered stent grafts. However, certain features such as a short wide neck, small vessel diameters, and significant vessel tortuosity can limit these two options. We describe a 75-year-old man with a splenic and celiac trunk aneurysm that was treated using a combination of coil embolization to occlude the outflow artery and aneurysm sac, and an aortic stent graft cuff to block the inflow...
March 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28283438/exome-sequencing-identified-a-novel-smad2-mutation-in-a-chinese-family-with-early-onset-aortic-aneurysms
#20
Wenwen Zhang, Qingfu Zeng, Yingqi Xu, Houqun Ying, Wei Zhou, Qing Cao, Weimin Zhou
Aortic aneurysm remains a devastating disease due to its fatal complications, such as aortic dissection and rupture. A subset of aortic aneurysm is caused by genetic defect and to date more than a dozen of disease-causing genes have been discovered to account for the disease. In this study, by using whole exome sequencing, we identified a novel heterozygous missense mutation (c.833C>T, p.A278V) in the SMAD2 gene in a family with early onset aortic aneurysms. The mutation segregated in this family, was high conserved among species and predicted to be pathogenic by multiple in silico programs...
March 7, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
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