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JOURNAL ARTICLE
Natsuki Sugiyama, Ryo Miyahara, Hiroshi Hasegawa, Kentaro Kudo, Rikizo Saito, Chikashi Maruki, Satoshi Tsutsumi
The superior thyroid cornu (STC) is a normal anatomic structure that forms part of the thyroid cartilage. Here, we report a patient with unusually elongated and ossified STC that might result in recurrent cerebral embolisms. During a second endovascular therapy for recurrent middle cerebral artery embolism, a segment with an irregular filling defect was noted in the internal carotid artery (ICA), at the C1 level. This defect was unnoticed during the initial endovascular procedure. Three-dimensional computed tomography angiography performed after the second endovascular procedure revealed an ICA segment located between the STC and C1 with a tortuous course and irregular wall of the ICA...
April 23, 2024: Surgical and Radiologic Anatomy: SRA
#2
JOURNAL ARTICLE
Kaori Miwa, Michikazu Nakai, Sohei Yoshimura, Yusuke Sasahara, Shinichi Wada, Junpei Koge, Akiko Ishigami, Yoshiki Yagita, Kenji Kamiyama, Yoshihiro Miyamoto, Shotai Kobayashi, Kazuo Minematsu, Kazunori Toyoda, Masatoshi Koga
BACKGROUND AND AIM: To investigate the prognostic implication of body mass index (BMI) on clinical outcomes after acute ischemic and hemorrhagic stroke. METHODS: The subjects of the study included adult patients with available baseline body weight and height data who had suffered an acute stroke and were registered in the Japan Stroke Data Bank-a hospital-based, multicenter stroke registration database-between January 2006 and December 2020. The outcome measures included unfavorable outcomes defined as a modified Rankin Scale [mRS] score of 5-6 and favorable outcomes (mRS 0-2) at discharge, and in-hospital mortality...
April 23, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
#3
JOURNAL ARTICLE
Yi Zhou, Xiaomei Jin, Xiaorong Liu, Jiafan Tang, Liyan Song, Yu Zhu, Wanqing Zhai, Xianhui Wang
PURPOSE: To explore the relationship between obstructive sleep apnea (OSA) and hypoperfusion during ultra-early acute cerebral infarction. PATIENTS AND METHODS: Data were retrospectively collected from patients admitted to our hospital with acute cerebral infarction between January 2020 and January 2022, who underwent comprehensive whole-brain computed tomography perfusion imaging and angiography examinations within 6 h of onset. The F-stroke software automatically assessed and obtained relevant data (Tmax)...
2024: Frontiers in Neurology
#4
JOURNAL ARTICLE
Zhengyang Wang, Ling Li
BACKGROUND: Endovascular treatment (EVT) is effective for large vessel occlusion (LVO) stroke with smaller volumes of CT perfusion (CTP)-defined core. However, the influence of perfusion imaging during thrombectomy on the functional outcomes of patients with large ischemic core (LIC) stroke at both early and late time windows is uncertain in real-world practice. METHOD: A retrospective analysis was performed on 99 patients who underwent computed tomography angiography (CTA) and CT perfusion (CTP)-Rapid Processing of Perfusion and Diffusion (RAPID) before EVT and had a baseline ischemic core ≥ 50 mL and/or Alberta Stroke Program Early CT Score (ASPECTS) score of 0-5...
April 23, 2024: Neurosurgical Review
#5
JOURNAL ARTICLE
Johan Wassélius, Emma Hall, Birgitta Ramgren, Tommy Andersson, Teresa Ullberg
INTRODUCTION: Several studies have addressed technical aspects of endovascular thrombectomy (EVT), but it is not well known how procedural factors contribute to technical success in routine healthcare. The aim was to explore factors associated with technically successful EVT on nationwide scale. METHODS: We did an observational register-based study assessing factors associated with technical success off anterior circulation EVT in Sweden. The main outcome was successful recanalization defined as modified treatment in cerebral ischemia score 2b-3...
April 22, 2024: Interventional Neuroradiology
#6
JOURNAL ARTICLE
Juan Liu, Min Zhang, Jiandi Huang, Changwei Guo, Jie Yang, Chengsong Yue, Wenjie Zi, Qingwu Yang
PURPOSE: Acute ischemic stroke (AIS) stands as the primary cause of mortality and extended disability globally. While prior studies have examined the connection between stroke and local weather, they have produced conflicting results. Our goal was to examine the correlation between temperature and functional prognosis in patients with large vessel occlusion (LVO) undergoing endovascular therapy (EVT). PATIENTS AND METHODS: This study included a total of 1809 patients...
2024: Clinical Interventions in Aging
#7
Michael Sabina, Zein Barakat, Jennifer M Jost, Rachel Tatro, Wan Sai
This report of two cases confronts the longstanding perception of Sickle Cell Trait (SCT) as a clinically benign condition, highlighting its complex and severe clinical manifestations, particularly in the context of blood loss anemia and vaso-occlusive crises (VOCs). The hallmark of sickle cell disease is the severe pain caused by acute vaso-occlusion of the microvasculature that leads to bone marrow infarction. We report two cases of patients with SCT and severe anemia in the setting of blood loss secondary to uterine fibroids subsequently causing VOCs with likely bone sequestration...
March 2024: Curēus
#8
Tatsuro Takei, Takashi Kajiya, Toshiko Ninomiya, Keisuke Yamamoto, Katsuyuki Imamura, Nobuhiko Atsuchi
UNLABELLED: Acute limb ischemia (ALI) related to total knee arthroplasty (TKA) is rare. Most occlusions are caused by thrombus formation in the popliteal artery (PA). Currently such cases are revascularized using less invasive approaches such as endovascular therapy or Fogarty thrombectomy. We report a case of ALI in a 65-year-old woman with complete rupture of the PA due to a TKA procedure. She had resting pain and motor paralysis in her right lower extremity after TKA. Contrast-enhanced computed tomography showed occlusion of the right femoropopliteal artery...
April 2024: Journal of Cardiology Cases
#9
Takahiro Tezuka, Hiroyoshi Mori, Hiroki Nishiwaki, Yosuke Takei, Natsuki Taira, Ayumi Omura, Daisuke Wada, Hiromoto Sone, Kazuma Tashiro, Tokutada Sato, Yoshitaka Iso, Mio Ebato, Hiroshi Suzuki
UNLABELLED: Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS), which typically occurs in women at low risk of atherosclerosis. We herein report a case of SCAD in a 57-year-old man who later developed Takayasu arteritis. The patient presented to our hospital complaining of chest pain and was diagnosed with unstable angina. Emergent coronary angiography was performed, and optical coherence tomography revealed that ACS was caused by SCAD. The patient was treated medically without further ballooning or stenting...
April 2024: Journal of Cardiology Cases
#10
JOURNAL ARTICLE
Leyla Ramazanoglu, Kalyoncu Isil Aslan, Yilmaz Onal, Murat Velioglu, Osman Melih Topcuoglu
BACKGROUND: The safety and efficacy of mechanical thrombectomy (MT) for proximal large vessel occlusion after acute ischemic stroke (AIS) have been demonstrated. Clinical investigations of endovascular approaches for treating AIS due to M2 occlusions have been ongoing. PURPOSE: To assess the outcomes of M2 occlusions according to treatment modality and anatomical division. METHODS: A total of 113 consecutive M2 occlusions treated with endovascular treatment (EVT) at our tertiary stroke center between January 2019 and December 2022 were retrospectively analyzed...
April 22, 2024: Acta Radiologica
#11
JOURNAL ARTICLE
K Y Manisha, Rajalakshmi Poyuran, Deepthi Narasimhaiah, Naveen Kumar Paramasivan, Harikrishnan Ramachandran, Sapna Erat Sreedharan, Jayadevan Er, Santhosh Kumar, Jissa Vinoda Thulaseedharan, P N Sylaja
BACKGROUND: There is conflicting data on whether clot retrieved from mechanical thrombectomy can predict stroke etiology or the success of recanalization. We aimed to analyse the relation between thrombus histology and stroke aetiology as well as recanalization. METHODOLOGY: Histopathological analysis of clots retrieved from patients with acute ischemic stroke and large vessel occlusion was done. Quantification of the amount of fibrin, red blood cells(RBC), platelets and white blood cells (WBC) in the clots were done...
April 20, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
#12
JOURNAL ARTICLE
Aysenur Onalan, Erdem Gurkas, Cetin Kursad Akpinar, Ozlem Aykac, Zehra Uysal Kocabas, Hasan Dogan, Musa Temel, Atilla Ozcan Ozdemir
INTRODUCTION: The awareness of nonocclusive thrombus has increased with the increasing frequency of imaging methods used for acute ischemic stroke; however, the best treatment for nonocclusive thrombi is still unknown. In this study, we examined how anticoagulants affect supra-aortic artery nonocclusive thrombus and clinical outcomes. MATERIALS AND METHODS: This study included 52 patients with transient ischemic attack or stroke who were diagnosed with nonocclusive thrombi on computed tomography angiography at admission...
April 20, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
#13
JOURNAL ARTICLE
James H Paxton, Kevin J Keenan, John M Wilburn, Stefanie L Wise, Howard A Klausner, Matthew T Ball, Robert B Dunne, K Derek Kreitel, Larry F Morgan, William D Fales, Debbie Madhok, Nobl Barazangi, Steven T McLean, Katherine Cross, Lisa Distenfield, Jordan Sykes, Paul Lovoi, Beth Johnson, Wade S Smith
BACKGROUND: Large-vessel occlusion (LVO) stroke represents one-third of acute ischemic stroke (AIS) in the United States but causes two-thirds of poststroke dependence and >90% of poststroke mortality. Prehospital LVO stroke detection permits efficient emergency medical systems (EMS) transport to an endovascular thrombectomy (EVT)-capable center. Our primary objective was to determine the feasibility of using a cranial accelerometry (CA) headset device for prehospital LVO stroke detection...
April 21, 2024: Academic Emergency Medicine
#14
JOURNAL ARTICLE
Jiuning Tang, Xinhai Zhang, Jinhui Yu, Zhi Liu, Huaqiang Ding
BACKGROUND: Although contrast extravasation on follow-up head computed tomography (CT) is frequently visualized after endovascular treatment, this phenomenon is rare after intravenous thrombolytic treatment in patients with acute ischemic stroke (AIS). Here, we report a case of contrast extravasation mimicking intracerebral hemorrhage (ICH) with intraventricular extension after intravenous thrombolytic treatment and computed tomography angiography (CTA). CASE PRESENTATION: A 52-year-old man presented with right-sided hemiparesis and hypoesthesia...
April 19, 2024: BMC Neurology
#15
JOURNAL ARTICLE
Jiaqian Li, Binda Wang, Fangyu Dai, Xuelian Kou, Guangyong Wu, Bin Wu, Jie Xu, Lulan Pan, Jingjing Liu, Songbin He, Feng Gao
BACKGROUND: F-actin is involved in the progression of ischemic stroke and is associated with the disruption of the blood-brain barrier. In this article, we evaluated serum F-actin as a biomarker in stroke severity and early neurological deterioration (END) in acute ischemic stroke. METHODS: In this study, serum F-actin was measured in consecutively collected 140 AIS patients and 144 healthy controls matched in gender and age by ELISA. Early neurological deterioration (END) was defined as the deterioration of neurological dysfunction within 72 hours of admission, with an increase of ≥ 4 points in the NIHSS score...
April 17, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#16
JOURNAL ARTICLE
Yu Wang, Jie Zhang, Lin Dai, Yongmei Kong, Yuqing Wei, Lijuan Wu, Juntao Yin
Leukocyte counts and ratios are independent biomarkers to determine the severity and prognosis of acute ischemic stroke (AIS). In AIS, the connection between leukocytes and large vessel occlusion (LVO) is uncertain. This study aims to determine the relationship between the existence of LVO and leukocyte counts and ratios on admission to AIS. Patients were retrospectively evaluated within six hours of AIS starting between January 2019 and April 2023. On admission, blood specimens were collected, and leukocyte subtype counts were promptly analyzed...
April 19, 2024: Medicine (Baltimore)
#17
JOURNAL ARTICLE
Cornelius Deuschl, Lukas Goertz, Christoph Kabbasch, Martin Köhrmann, Christoph Kleinschnitz, Ansgar Berlis, Christoph Johannes Maurer, Iris Mühlen, Bernd Kallmünzer, Matthias Gawlitza, Daniel P O Kaiser, Joachim Klisch, Donald Lobsien, Daniel Behme, Maximilian Thormann, Fabian Flottmann, Laurens Winkelmeier, Elke Ruth Gizewski, Lukas Mayer-Suess, Markus Holtmannspoetter, Christoph Moenninghoff, Martin Schlunz-Hendann, Dominik Grieb, Christophe T Arendt, Ferdinand O Bohmann, Jens Altenbernd, Yan Li, Ulrich Sure, Ruben Mühl-Benninghaus, Thomas Rodt, Kai Kallenberg, Alexandru Durutya, Mohamed Elsharkawy, Christian-Paul Stracke, Mathias Gerhard Schumann, Alexander Bock, Omid Nikoubashman, Martin Wiesmann, Hans Henkes, Sebastian Dolff, Aydin Demircioglu, Michael Forsting, Hanna Styczen
BACKGROUND: Data on impact of COVID-19 vaccination and outcomes of patients with COVID-19 and acute ischemic stroke undergoing mechanical thrombectomy are scarce. Addressing this subject, we report our multicenter experience. METHODS AND RESULTS: This was a retrospective analysis of patients with COVID-19 and known vaccination status treated with mechanical thrombectomy for acute ischemic stroke at 20 tertiary care centers between January 2020 and January 2023. Baseline demographics, angiographic outcome, and clinical outcome evaluated by the modified Rankin Scale score at discharge were noted...
April 19, 2024: Journal of the American Heart Association
#18
JOURNAL ARTICLE
Kaixi Ren, Songwang Hou, Steven E Johnson, Jon Lomasney, Chad R Haney, Jungwha Lee, Zhi-Dong Ge, Daniel C Lee, Jeffrey J Goldberger, Rishi Arora, Ming Zhao
BACKGROUND: The goal was to determine the feasibility of mapping the injured-but-not-infarcted myocardium using 99m Tc-duramycin in the postischemic heart, with spatial information for its characterization as a pathophysiologically intermediate tissue, which is neither normal nor infarcted. METHODS AND RESULTS: Coronary occlusion was conducted in Sprague Dawley rats with preconditioning and 30-minute ligation. In vivo single-photon emission computed tomography was acquired after 3 hours (n=6) using 99m Tc-duramycin, a phosphatidylethanolamine-specific radiopharmaceutical...
April 19, 2024: Journal of the American Heart Association
#19
JOURNAL ARTICLE
Ziyan Jin, Zihong Shen, Siyang Yan, Guolei Chen, Yalong Yin, You Zhang, Xingui Wu
BACKGROUND: The use of proton pump inhibitors in the acute phase of cerebral infarction may lead to adverse long-term outcomes, this study aims to explore the potential of electroacupuncture (EA) in replacing omeprazole in exerting post-stroke gastrointestinal protection. METHODS: A permanent middle cerebral artery infarction model was established using the modified Longa thread occlusion technique. Gastrointestinal motility, gastrointestinal mucosal damage, cerebral infarct volume, and alterations in choline acetyltransferase (ChAT)-positive neurons within the dorsal motor nucleus of the vagus nerve (DMV) were assessed after 7 days of EA at Zusanli (ST36) or omeprazole intervention...
April 30, 2024: Heliyon
#20
JOURNAL ARTICLE
Lina Zheng, Ximing Nie, Mengxing Wang, Xin Liu, Wanying Duan, Zhe Zhang, Jingyi Liu, Yufei Wei, Miao Wen, Zhonghua Yang, Thomas W Leung, Gaoting Ma, Xiaochuan Huo, Yuesong Pan, Thanh N Nguyen, Xinyi Leng, Zhongrong Miao, Liping Liu
BACKGROUND: Endovascular therapy (EVT) was demonstrated effective in acute large vessel occlusion (LVO) with large infarction. Revealing subgroups of patients who would or would not benefit from EVT will further inform patient selection for EVT. METHODS: This post-hoc analysis of the ANGEL-ASPECT trial, a randomised controlled trial of 456 adult patients with acute anterior-circulation LVO and large infarction, defined by ASPECTS 3-5 or infarct core volume 70-100 mL, enrolled from 46 centres across China, between October 2, 2020 and May 18, 2022...
June 2024: EClinicalMedicine
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