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t peak to t end /qt ratio

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https://www.readbyqxmd.com/read/27904512/evaluation-of-inhomogeneities-of-repolarization-in-patients-with-psoriasis-vulgaris
#1
Korhan Soylu, Sinan İnci, Gökhan Aksan, Gökay Nar, Esra Pancar Yüksel, Hande Serra Ocal, Mustafa Çapraz, Serkan Yüksel, Mahmut Şahin
INTRODUCTION: The arrhythmia potential has not been investigated adequately in psoriatic patients. In this study, we assessed the ventricular repolarization dispersion, using the Tp-e interval and the Tp-e/QT ratio, and investigated the association with inflammation. MATERIAL AND METHODS: Seventy-one psoriasis vulgaris patients and 70 age- and gender-matched healthy individuals were enrolled in the study. The severity of the disease was calculated using Psoriasis Area and Severity Index scoring...
December 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27610610/evaluation-of-tp-e-interval-tp-e-qt-ratio-and-tp-e-qtc-ratio-in-patients-with-asymptomatic-arrhythmogenic-right-ventricular-cardiomyopathy
#2
Elnur Alizade, Mahmut Yesin, Mehmet Vefik Yazicioğlu, Ekrem Bilal Karaayvaz, Adem Atici, Şükrü Arslan, Anıl Avci, Göksel Acar, Mustafa Tabakci, Servet Izci, Selçuk Pala
BACKGROUND: Arrhythmogenic right ventricular dysplasia (ARVD) is characterized by progressive replacement of ventricular myocytes with variable amounts of fibrous and adipose tissue. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. The aim of this study was to evaluate repolarization dispersion measured from the 12-lead surface electrocardiogram (including Tp-e interval, Tp-e/QT, and Tp-e/QTc ratio) in asymptomatic ARVD patients METHODS: We selected 27 patients with asymptomatic ARVD and 27 age- and gender-match young, healthy volunteers...
March 28, 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/27554253/variability-of-myocardial-repolarization-in-pediatric-patients-with-a-ventricular-septal-defect
#3
Hidetoshi Uchida, Miki Nishio, Yumi Omeki, Yuka Takeuchi, Rina Nagata, Shota Oikawa, Arisa Nagatani, Yoshihiko Eryu, Tadayoshi Hata, Tetsushi Yoshikawa
: In patients with a ventricular septal defect, left-to-right shunting increases the left ventricular preload. This pathological change affects myocardial depolarization and repolarization and has the potential to evoke arrhythmogenic substrates. We examined the effect of ventricular septal defects on myocardial repolarization by investigating the variability in the repolarization interval. This retrospective study included 19 patients (mean age, 1.8 ± 2.1 years) who underwent surgical closure (mean left-to-right shunt ratio, 2...
December 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27441471/electrocardiographic-abnormalities-and-arrhythmic-risk-markers-in-adult-patients-with-beta-thalassemia-major
#4
Marios Kolios, Panagiotis Korantzopoulos, Antonios P Vlahos, Eleni Kapsali, Evangelos Briasoulis, John A Goudevenos
BACKGROUND: There seems to be a significant arrhythmia burden in β-thalassemia major (TM) patients without overt cardiomyopathy. Apart from conventional electrocardiographic (ECG) and arrhythmic risk markers we studied novel markers of ventricular repolarization and autonomic imbalance both at rest and after exercise testing. METHODS: We studied 47 adult TM patients without systolic heart failure and 47 age and sex-matched healthy control subjects. The median age of the studied population was 36 [32-43] years, 57% men...
October 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27251411/prolonged-tp-e-interval-and-tp-e-qt-ratio-in-children-with-mitral-valve-prolapse
#5
Mustafa Demirol, Cem Karadeniz, Rahmi Ozdemir, Şenay Çoban, Nagehan Katipoğlu, Yılmaz Yozgat, Timur Meşe, Nurettin Unal
Although it is considered to be a benign condition, previous studies have shown that a subset of patients with mitral valve prolapse (MVP) may be at risk of ventricular arrhythmia and sudden cardiac death (SCD). Previous studies have suggested that the interval between the peak and the end of the T wave (Tp-e) can be used as a marker for the transmural dispersion of repolarization. Increased Tp-e interval and Tp-e/QT ratio are associated with ventricular arrhythmias and SCD. The aim of this study was to assess alterations in ventricular repolarization by using the Tp-e interval and Tp-e/QT ratio in children with MVP and to investigate their relationships with the degree of valvular regurgitation...
August 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27019094/impact-of-iron-and-homocysteine-levels-on-t-peak-to-end-interval-and-tp-e-qt-ratio-in-elite-athletes
#6
Serkan Duyuler, Pınar Türker Duyuler, Mustafa Kemal Batur
BACKGROUND: Electrocardiography (ECG) is frequently used in preparticipation evaluation of competitive athletes. Repolarization heterogeneities on ECG is a well-known indicator for malignant ventricular arrhythmias and sudden cardiac death. We aimed to investigate the effect of iron and homocysteine levels on arrhythmogenic indicators, T peak-to-end (Tp-e) interval, and Tp-e/QT ratio in elite athletes. METHODS: A total of 72 players (48 football and 24 basketball) with a mean age of 25...
March 28, 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/26928618/familial-mediterranean-fever-is-associated-with-abnormal-ventricular-repolarization-indices
#7
Elbis Ahbap, Tamer Sakaci, Ekrem Kara, Tuncay Sahutoglu, Semi Ozturk, Taner Basturk, Yener Koc, Mustafa Sevinc, Cuneyt Akgol, Zuhal Atan Ucar, Arzu Ozdemir Kayalar, Feyza Bayraktar Caglayan, Seyfettin Gurbuz, Abdulkadir Unsal
BACKGROUND: Cardiac arrhythmias can be a part of cardiovascular involvement in some rheumatic diseases, but data about familial Mediterranean fever (FMF) are conflicting. AIM: To search for abnormalities in ventricular repolarization indices in FMF patients. PATIENTS AND METHODS: Seventy seven FMF patients and 30 age/gender comparable healthy controls were included. All patients were attack free and subjects with disease or drugs that are known to alter cardiac electrophysiology were excluded...
December 2015: Revista Médica de Chile
https://www.readbyqxmd.com/read/26885300/arrhythmogenic-potential-develops-rapidly-at-graft-reperfusion-before-the-start-of-hypotension-during-living-donor-liver-transplantation
#8
Hwa-Mi Lee, Soo-Kyoung Park, Young-Jin Moon, Jung-Won Kim, Sun-Key Kim, Bo-Hyun Sang, Dong-Kyun Seo, Byoung-Woo Yoo, Gyu-Sam Hwang
BACKGROUND: Detailed profiles of acute hypothermia and electrocardiographic (ECG) manifestations of arrhythmogenicity were examined to analyze acute hypothermia and ventricular arrhythmogenic potential immediately after portal vein unclamping (PVU) in living-donor liver transplantation (LT). METHODS: We retrospectively analyzed electronically archived medical records (n = 148) of beat-to-beat ECG, arterial pressure waveforms, and blood temperature (BT) from Swan-Ganz catheters in patients undergoing living-donor LT...
February 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/26676332/prolonged-tp-e-interval-tp-e-qt-ratio-and-tp-e-qtc-ratio-in-patients-with-type-2-diabetes-mellitus
#9
Alptug Tokatli, Fethi Kiliçaslan, Metin Alis, Omer Yiginer, Mehmet Uzun
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with increased risk of malignant ventricular arrhythmias. Cardiac electrical inhomogeneity may be the leading cause of the increased arrhythmic risk in patients with T2DM. The peak and the end of the T wave (Tp-e) interval and associated Tp-e/QT ratio are promising measures of ventricular repolarization indicating transmural dispersion of repolarization. The aim of this study was to assess ventricular repolarization in patients with T2DM by using Tp-e interval, Tp-e/QT ratio and Tp-e/corrected QT interval (QTc) ratio...
March 2016: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/26465871/evaluation-of-electrocardiographic-t-peak-to-t-end-interval-in-subjects-with-increased-epicardial-fat-tissue-thickness
#10
Ozgur Kaplan, Ertugrul Kurtoglu, Gokay Nar, Erdogan Yasar, Gokhan Gozubuyuk, Cem Dogan, Ahmet Ugur Boz, Sıho Hidayet, Hasan Pekdemir
BACKGROUND: The association between periatrial adiposity and atrial arrhythmias has been shown in previous studies. However, there are not enough available data on the association between epicardial fat tissue (EFT) thickness and parameters of ventricular repolarization. Thus, we aimed to evaluate the association of EFT thickness with indices of ventricular repolarization by using T-peak to T-end (Tp-e) interval and Tp-e/QT ratio. METHODS: The present study included 50 patients whose EFT thickness ≥ 9 mm (group 1) and 40 control subjects with EFT thickness < 9 mm (group 2)...
December 2015: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/26410545/the-t-peak-t-end-interval-as-a-marker-of-repolarization-abnormality-a-comparison-with-the-qt-interval-for-five-different-drugs
#11
Tanveer A Bhuiyan, Claus Graff, Jørgen K Kanters, Jimmi Nielsen, Jacob Melgaard, Jørgen Matz, Egon Toft, Johannes J Struijk
BACKGROUND AND OBJECTIVE: The T-peak to T-end (TpTe) interval has been suggested as an index of transmural dispersion and as a marker of drug-induced abnormal repolarization. In this study, we investigate the relation between TpTe and the QT interval. METHODS: Electrocardiograms (ECGs) from five different drugs (sotalol, sertindole, moxifloxacin, nalmefene, and Lu 38-135) and from a placebo group were analyzed. Semi-automatic measurements of T-peak, T-end, and QRS onset were obtained...
November 2015: Clinical Drug Investigation
https://www.readbyqxmd.com/read/26209300/assessment-of-electrocardiographic-parameters-in-patients-with-electrocution-injury
#12
Mehmet Baran Karataş, Tolga Onuk, Barış Güngör, Göktürk İpek, Kazım Serhan Özcan, Mustafa Kaplangöray, Yiğit Çanga, Gündüz Durmuş, Yasin Çakıllı, Osman Bolca
BACKGROUND: Electrocution injury (EI) is a major problem in developing countries. The aim of this study is to investigate the effect of EI on electrocardiographic (ECG) parameters. METHODS: A total of 43 patients hospitalized with diagnosis of EI were prospectively enrolled. Admission ECGs were compared with follow-up ECGs obtained one month after the event. RESULTS: Maximum P wave duration (Pmax), minimum P wave duration (Pmin), P wave dispersion (PWD), PR interval, QRS complex duration, corrected QT duration (QTc), QT dispersion (QTD), T peak to T end (Tp-e) interval were longer and Tp-e interval/QT and Tp-e interval/QTc ratios were higher on admission ECGs compared to follow-up ECGs...
September 2015: Journal of Electrocardiology
https://www.readbyqxmd.com/read/26209263/increased-tpeak-tend-interval-is-highly-and-independently-related-to-arrhythmic-events-in-brugada-syndrome
#13
MULTICENTER STUDY
Philippe Maury, Frederic Sacher, Jean-Baptiste Gourraud, Jean-Luc Pasquié, Franck Raczka, Vanina Bongard, Alexandre Duparc, Pierre Mondoly, Marie Sadron, Stephanie Chatel, Nicolas Derval, Arnaud Denis, Christelle Cardin, Jean-Marc Davy, Meleze Hocini, Pierre Jaïs, Laurence Jesel, Didier Carrié, Michel Galinier, Michel Haïssaguerre, Vincent Probst, Anne Rollin
BACKGROUND: Risk stratification in Brugada syndrome (BS) remains controversial. The time interval between the peak and the end of the T wave (Tpe interval), a marker of transmural dispersion of repolarization, has been linked to malignant ventricular arrhythmias in various settings but leads to discordant results in BS. OBJECTIVE: We study the correlation of the Tpe interval with arrhythmic events in a large cohort of patients with BS. METHODS: A total of 325 consecutive patients with BS (mean age 47±13 years, 259 men-80%) with spontaneous (n=143, 44%) or drug-induced (n=182, 56%) type 1 electrocardiogram were retrospectively included...
December 2015: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/26180494/evaluation-of-tp-te-interval-and-tp-te-qt-ratio-in-patients-with-coronary-slow-flow-tp-te-qt-ratio-and-coronary-slow-flow
#14
Erhan Tenekecioglu, Kemal Karaagac, Osman Can Yontar, Fahriye Vatansever Agca, Ozlem Arican Ozluk, Ahmet Tutuncu, Burhan Arslan, Mustafa Yilmaz
OBJECTIVE: Coronary slow flow (CSF) phenomenon is described by angiographically normal coronary arteries with delayed opacification of the distal vasculature. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-Te) may correspond to the transmural dispersion of the repolarization and that increased Tp-Te interval and Tp-Te/QT ratio are associated with malignant ventricular arrhythmias. The aim of this study was to evaluate the ventricular repolarization by using Tp-Te interval and Tp-Te/QT ratio in patients with CSF...
June 2015: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/26174604/impact-of-percutaneous-coronary-intervention-on-exercise-induced-repolarization-changes-in-patients-with-stable-coronary-artery-disease
#15
Anita Jukić, Vedran Carević, Dražen Zekanović, Sanda Stojanović-Stipić, Frane Runjić, Marko Ljubković, Damir Fabijanić
Recent reports suggest T peak to T end (Tpe) interval and Tpe/QT ratio as valuable indicators of increased arrhythmogenic risk in patients with coronary artery disease (CAD). We aimed to examine the exercise-induced changes in these indexes in patients with stable CAD, before and after percutaneous coronary intervention (PCI). Forty patients were consecutively included in the interventional group (n = 20), with significant lesions (≥75% luminal narrowing) suitable for PCI and in the control group (n = 20), with no significant coronary artery lesions (<50% luminal narrowing)...
September 15, 2015: American Journal of Cardiology
https://www.readbyqxmd.com/read/26100824/the-effect-of-varenicline-on-tp-e-interval-tp-e-qt-ratio-and-tp-e-qtc-ratio-in-healthy-smokers-and-nonsmokers
#16
RANDOMIZED CONTROLLED TRIAL
Hasan Ari, Selma Ari, Selvi Coşar, Nuran Celiloğlu, İbrahim Aktaş, Sencer Camci, Kübra Doğanay, Ahmet Tütüncü, Mehmet Melek
BACKGROUND: Varenicline could affect the T wave and QT interval. The interval from the peak to the end of the electrocardiographic (ECG) T wave (Tp-e) may correspond to the transmural dispersion of repolarization, and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. In this study, we assessed the effects of varenicline on Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio. METHODS: Thirty healthy volunteers (15 healthy non-smokers [NS] and 15 healthy smokers [S]) were included in the randomized, double-blind, placebo-controlled, crossover study...
2015: Cardiology Journal
https://www.readbyqxmd.com/read/26084968/electrocardiographic-p-wave-duration-qt-interval-t-peak-to-end-interval-and-tp-e-qt-ratio-in-pregnancy-with-respect-to-trimesters
#17
Asli Tanindi, Nilufer Akgun, Emre Goksan Pabuccu, Aslı Yarci Gursoy, Ebru Yüce, Hasan Fehmi Tore, Candan Iltemir Duvan
BACKGROUND: P-wave duration helps to determine the risk of atrial arrhythmia, especially atrial fibrillation. QT interval, T peak to end interval (Tp-e), and Tp-e/QT ratio are electrocardiographic indices related to ventricular repolarization which are used to determine the risk of ventricular arrhythmias. We search for any alterations in electrocardiographic indices of arrhythmia in the pregnancy period with respect to trimesters. METHODS: We enrolled 154 pregnant and 62 nonpregnant, healthy women into this cross-sectional study...
March 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/26056451/evaluation-of-acute-cardiovascular-effects-of-immediate-release-methylphenidate-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder
#18
Marco Lamberti, Domenico Italiano, Laura Guerriero, Gessica D'Amico, Rosamaria Siracusano, Massimo Ingrassia, Eva Germanò, Maria Pia Calabrò, Edoardo Spina, Antonella Gagliano
Attention-deficit hyperactivity disorder is a frequent condition in children and often extends into adulthood. Use of immediate-release methylphenidate (MPH) has raised concerns about potential cardiovascular adverse effects within a few hours after administration. This study was carried out to investigate acute effects of MPH on electrocardiogram (ECG) in a pediatric population. A total of 54 consecutive patients with attention-deficit hyperactivity disorder (51 males and 3 females; mean age =12.14±2.6 years, range 6-19 years), receiving a new prescription of MPH, underwent a standard ECG 2 hours before and after the administration of MPH 10 mg per os...
2015: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/25887095/effects-of-droperidol-and-ondansetron-on-dispersion-of-ventricular-repolarization-a-randomized-double-blind-clinical-study-in-anesthetized-adult-patients
#19
G L Agámez Medina, A González-Arévalo, J I Gómez-Arnau, S García del Valle, J A Rubio, E Esteban, E Pérez
BACKGROUND AND OBJECTIVE: Droperidol and ondansetron prolong QT interval, a circumstance that has raised some concerns regarding the possibility of inducing torsades de pointes (TdP). However drug-induced spatial dispersion of ventricular repolarization has been shown to be the principal arrhythmogenic substrate for TdP. The aim of this study is to explore the effects of droperidol and ondansetron on the dispersion of repolarization, measured using the T peak-to-end interval (Tp-e) and Tp-e/QT and Tp-e/RR(1/2) ratios in surgical anesthetized patients...
November 2015: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/25868042/acute-effects-of-red-bull-energy-drink-on-ventricular-repolarization-in-healthy-young-volunteers-a-prospective-study
#20
Ali Elitok, Fahrettin Öz, Cafer Panc, Remzi Sarıkaya, Selim Sezikli, Yasin Pala, Övgü Sinem Bugan, Müge Ateş, Hilal Parıldar, Mustafa Buğra Ayaz, Adem Atıcı, Hüseyin Oflaz
OBJECTIVE: Energy drinks (EDs) are widely consumed products of the beverage industry and are often chosen by teenagers and young adults. Several adverse cardiovascular events and malignant cardiac arrhythmias following consumption of EDs have been reported in the literature. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the dispersion of repolarization and that an increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias...
November 2015: Anatolian Journal of Cardiology
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