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t peak to t end /qt ratio

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https://www.readbyqxmd.com/read/28449908/association-of-sleep-disordered-breathing-and-disturbed-cardiac-repolarization-in-patients-with-st-segment-elevation-myocardial-infarction
#1
Christoph Fisser, Alina Marcinek, Andrea Hetzenecker, Kurt Debl, Andreas Luchner, Ulrich Sterz, Jörg Priefert, Florian Zeman, Malcolm Kohler, Lars S Maier, Stefan Buchner, Michael Arzt
OBJECTIVE: In patients with ST-segment elevation myocardial infarction (STEMI), disturbed cardiac repolarization before percutaneous coronary intervention (PCI) is a risk factor for malignant ventricular arrhythmia. We tested the hypothesis that sleep-disordered breathing (SDB) in patients with STEMI is associated with disturbed cardiac repolarization. METHODS: Thirty-three patients with STEMI who underwent PCI were prospectively enrolled. To assess cardiac repolarization, the heart-rate corrected interval from the peak of the T wave to the end of the T wave (TpTec) and QTc intervals were assessed with 12-lead electrocardiography before PCI, within 24 h after PCI, and 12 weeks after PCI...
May 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28377800/evaluation-of-tp-e-interval-tp-e-qt-ratio-and-tp-e-qtc-ratio-in-patients-with-subclinical-hypothyroidism
#2
Ahmet Gürdal, Hatice Eroğlu, Füsun Helvaci, Mutlu Çağan Sümerkan, Kamber Kasali, Şükrü Çetin, Gökhan Aksan, Kadriye Kiliçkesmez
BACKGROUND: Prolongation of the peak-to-end interval of the T wave (Tp-e) has been reported as associated with ventricular arrhythmias. The aim of this study was to investigate the ventricular repolarization by using the Tp-e interval, Tp-e/QT ratio and Tp-e/ QTc ratio in patients with subclinical hypothyroidism (SH). METHODS: We studied 56 volunteers: These were 28 patients with SH (mean age 45 ± 11 years) and 28 healthy subjects (mean age 34 ± 8 years). All basic biochemical parameters were analyzed and electrocardiograms (ECGs) were recorded...
March 2017: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28315570/tp-e-interval-and-tp-e-qtc-ratio-as-novel-surrogate-markers-for-prediction-of-ventricular-arrhythmic-events-in-hypertrophic-cardiomyopathy
#3
Mehmet Kadri Akboğa, Kevser Gülcihan Balcı, Samet Yılmaz, Selahattin Aydın, Çağrı Yayla, Ahmet Göktuğ Ertem, Sefa Ünal, Mustafa Mücahit Balcı, Yücel Balbay, Dursun Aras, Serkan Topaloğlu
OBJECTIVE: Hypertrophic cardiomyopathy (HCM) as a common genetic heart disease characterized by ventricular hypertrophy and myocardial fibrosis is significantly associated with a higher risk of fatal ventricular arrhythmic events (VAEs). We aimed to assess the interval between the peak and the end of the electrocardiographic T wave (Tp-e) and Tp-e/corrected QT (QTc) ratio as candidate markers of ventricular arrhythmias in patients with HCM. METHODS: In this single-center, prospective study, a total of 66 patients with HCM and 88 controls were enrolled...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28274540/the-effect-of-metilpheniydate-risperidone-and-combination-therapy-on-ecg-in-children-with-attention-deficit-hyperactivity-disorder
#4
Derya Karpuz, Olgu Hallioglu, Fevziye Toros, Bahar Tasdelen
INTRODUCTION: This study is to investigate ventricular repolarization on electrocardiogram (ECG) in a pediatric population receiving methylphenidate (MPH), risperidone (RIS) and combined therapy. METHODS: A total of 215 patients between 6 and 12years with ADHD/conduct disorder receiving methylphenidate, risperidone and combined therapy for minimum 3months and an untreated ADHD group (n=76) was consecutively included in the study. Twelve lead ECG parameters including mean QT, QTc, T-peak to T-end (TpTe) intervals, TpTe dispersion and TpTe/QT ratio were compared...
July 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28121344/impact-of-myocardial-blush-grade-on-tpe-interval-and-tpe-qt-ratio-after-successful-primary-percutaneous-coronary-intervention-in-patients-with-st-elevation-myocardial-infarction
#5
P T Duyuler, S Duyuler, M Demir
INTRODUCTION: Myocardial perfusion, when assessed by myocardial blush grade (MBG) is an independent predictor of major adverse cardiac outcomes. The terminal part of repolarization, measured as the interval from the peak to the end of the T wave (Tpe), is a relatively novel indicator of ventricular arrhythmias. The relations between MBG and Tpe interval have not been examined before. We aimed to evaluate the relationship between MBG and Tpe and Tpe/QT ratio after successful primary percutaneous coronary intervention (PCI) in acute ST-segment elevation myocardial infarction (STEMI)...
January 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28110482/the-evaluation-of-a-new-marker-of-transmyocardial-repolarization-parameters-in-ischemic-stroke-patients-t-peak-t-end-t-p-e-t-p-e-qtc
#6
Emine Emektar, Şeref Kerem Çorbacıoğlu, Osman Korucu, Selma Ramadan, Hüseyin Uzunosmanoğlu, Eda Kan, Yunsur Çevik
The cardiovascular manifestations of acute ischemic stroke have been well known. Several electrocardiography (ECG) abnormalities have been reported in patients following acute stroke, including QT interval prolongation, ST segment deviation and T-wave changes. This study aimed to investigate the changes in transmyocardial repolarization parameters, in ischemic stroke patients. The study is a prospective, blind, and controlled clinical study. The patients without cardiac disease who received ischemic stroke diagnoses were included in the study...
January 21, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28100427/the-possible-role-of-propofol-in-drug-induced-torsades-de-pointes-a-real-world-single-center-analysis
#7
Victor A Abrich, Harish Ramakrishna, Arjun Mehta, Farouk Mookadam, Komandoor Srivathsan
BACKGROUND: Torsades de pointes (TdP) is a polymorphic ventricular tachycardia associated with QT prolongation. Propofol is a sedative-anesthetic with proarrhythmic effects on cardiac myocytes. We performed a retrospective study to determine the incidence of TdP following propofol exposure at Mayo Clinic (Rochester, MN) from 08/11/1998-11/20/2015. METHODS: We queried our database using key search terms to identify patients exposed to propofol who developed TdP perioperatively or during non-surgical sedation...
April 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28071178/psychotropic-drugs-and-ventricular-repolarisation-the-effects-on-qt-interval-t-peak-to-t-end-interval-and-qt-dispersion
#8
Tiziano Acciavatti, Giovanni Martinotti, Mariangela Corbo, Eduardo Cinosi, Matteo Lupi, Fabrizio Ricci, Rosa Di Scala, Emilia D'Ugo, Viola De Francesco, Raffaele De Caterina, Massimo di Giannantonio
OBJECTIVE: We aimed to investigate in a clinical setting, the effects of different classes of psychotropic drugs on cardiac electrophysiological measures linked with an increased risk of sudden cardiac death. METHODS: We conducted a cross-sectional study in a population of 1059 psychiatric inpatients studying the effects of various psychotropic drugs on the T-peak to T-end (TpTe) interval, QT dispersion and QT interval. RESULTS: Methadone use showed a strong association with TpTe prolongation (odds ratio (OR)=12...
April 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/27904512/evaluation-of-inhomogeneities-of-repolarization-in-patients-with-psoriasis-vulgaris
#9
Korhan Soylu, Sinan İnci, Gökhan Aksan, Gökay Nar, Esra Pancar Yüksel, Hande Serra Ocal, Mustafa Çapraz, Serkan Yüksel, Mahmut Şahin
INTRODUCTION: The arrhythmia potential has not been investigated adequately in psoriatic patients. In this study, we assessed the ventricular repolarization dispersion, using the Tp-e interval and the Tp-e/QT ratio, and investigated the association with inflammation. MATERIAL AND METHODS: Seventy-one psoriasis vulgaris patients and 70 age- and gender-matched healthy individuals were enrolled in the study. The severity of the disease was calculated using Psoriasis Area and Severity Index scoring...
December 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27610610/evaluation-of-tp-e-interval-tp-e-qt-ratio-and-tp-e-qtc-ratio-in-patients-with-asymptomatic-arrhythmogenic-right-ventricular-cardiomyopathy
#10
Elnur Alizade, Mahmut Yesin, Mehmet Vefik Yazicioğlu, Ekrem Bilal Karaayvaz, Adem Atici, Şükrü Arslan, Anıl Avci, Göksel Acar, Mustafa Tabakci, Servet Izci, Selçuk Pala
BACKGROUND: Arrhythmogenic right ventricular dysplasia (ARVD) is characterized by progressive replacement of ventricular myocytes with variable amounts of fibrous and adipose tissue. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. The aim of this study was to evaluate repolarization dispersion measured from the 12-lead surface electrocardiogram (including Tp-e interval, Tp-e/QT, and Tp-e/QTc ratio) in asymptomatic ARVD patients METHODS: We selected 27 patients with asymptomatic ARVD and 27 age- and gender-match young, healthy volunteers...
January 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/27554253/variability-of-myocardial-repolarization-in-pediatric-patients-with-a-ventricular-septal-defect
#11
Hidetoshi Uchida, Miki Nishio, Yumi Omeki, Yuka Takeuchi, Rina Nagata, Shota Oikawa, Arisa Nagatani, Yoshihiko Eryu, Tadayoshi Hata, Tetsushi Yoshikawa
In patients with a ventricular septal defect, left-to-right shunting increases the left ventricular preload. This pathological change affects myocardial depolarization and repolarization and has the potential to evoke arrhythmogenic substrates. We examined the effect of ventricular septal defects on myocardial repolarization by investigating the variability in the repolarization interval. This retrospective study included 19 patients (mean age, 1.8 ± 2.1 years) who underwent surgical closure (mean left-to-right shunt ratio, 2...
December 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27441471/electrocardiographic-abnormalities-and-arrhythmic-risk-markers-in-adult-patients-with-beta-thalassemia-major
#12
Marios Kolios, Panagiotis Korantzopoulos, Antonios P Vlahos, Eleni Kapsali, Evangelos Briasoulis, John A Goudevenos
BACKGROUND: There seems to be a significant arrhythmia burden in β-thalassemia major (TM) patients without overt cardiomyopathy. Apart from conventional electrocardiographic (ECG) and arrhythmic risk markers we studied novel markers of ventricular repolarization and autonomic imbalance both at rest and after exercise testing. METHODS: We studied 47 adult TM patients without systolic heart failure and 47 age and sex-matched healthy control subjects. The median age of the studied population was 36 [32-43] years, 57% men...
October 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27251411/prolonged-tp-e-interval-and-tp-e-qt-ratio-in-children-with-mitral-valve-prolapse
#13
Mustafa Demirol, Cem Karadeniz, Rahmi Ozdemir, Şenay Çoban, Nagehan Katipoğlu, Yılmaz Yozgat, Timur Meşe, Nurettin Unal
Although it is considered to be a benign condition, previous studies have shown that a subset of patients with mitral valve prolapse (MVP) may be at risk of ventricular arrhythmia and sudden cardiac death (SCD). Previous studies have suggested that the interval between the peak and the end of the T wave (Tp-e) can be used as a marker for the transmural dispersion of repolarization. Increased Tp-e interval and Tp-e/QT ratio are associated with ventricular arrhythmias and SCD. The aim of this study was to assess alterations in ventricular repolarization by using the Tp-e interval and Tp-e/QT ratio in children with MVP and to investigate their relationships with the degree of valvular regurgitation...
August 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27019094/impact-of-iron-and-homocysteine-levels-on-t-peak-to-end-interval-and-tp-e-qt-ratio-in-elite-athletes
#14
Serkan Duyuler, Pınar Türker Duyuler, Mustafa Kemal Batur
BACKGROUND: Electrocardiography (ECG) is frequently used in preparticipation evaluation of competitive athletes. Repolarization heterogeneities on ECG is a well-known indicator for malignant ventricular arrhythmias and sudden cardiac death. We aimed to investigate the effect of iron and homocysteine levels on arrhythmogenic indicators, T peak-to-end (Tp-e) interval, and Tp-e/QT ratio in elite athletes. METHODS: A total of 72 players (48 football and 24 basketball) with a mean age of 25...
November 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/26928618/familial-mediterranean-fever-is-associated-with-abnormal-ventricular-repolarization-indices
#15
Elbis Ahbap, Tamer Sakaci, Ekrem Kara, Tuncay Sahutoglu, Semi Ozturk, Taner Basturk, Yener Koc, Mustafa Sevinc, Cuneyt Akgol, Zuhal Atan Ucar, Arzu Ozdemir Kayalar, Feyza Bayraktar Caglayan, Seyfettin Gurbuz, Abdulkadir Unsal
BACKGROUND: Cardiac arrhythmias can be a part of cardiovascular involvement in some rheumatic diseases, but data about familial Mediterranean fever (FMF) are conflicting. AIM: To search for abnormalities in ventricular repolarization indices in FMF patients. PATIENTS AND METHODS: Seventy seven FMF patients and 30 age/gender comparable healthy controls were included. All patients were attack free and subjects with disease or drugs that are known to alter cardiac electrophysiology were excluded...
December 2015: Revista Médica de Chile
https://www.readbyqxmd.com/read/26885300/arrhythmogenic-potential-develops-rapidly-at-graft-reperfusion-before-the-start-of-hypotension-during-living-donor-liver-transplantation
#16
Hwa-Mi Lee, Soo-Kyoung Park, Young-Jin Moon, Jung-Won Kim, Sun-Key Kim, Bo-Hyun Sang, Dong-Kyun Seo, Byoung-Woo Yoo, Gyu-Sam Hwang
BACKGROUND: Detailed profiles of acute hypothermia and electrocardiographic (ECG) manifestations of arrhythmogenicity were examined to analyze acute hypothermia and ventricular arrhythmogenic potential immediately after portal vein unclamping (PVU) in living-donor liver transplantation (LT). METHODS: We retrospectively analyzed electronically archived medical records (n = 148) of beat-to-beat ECG, arterial pressure waveforms, and blood temperature (BT) from Swan-Ganz catheters in patients undergoing living-donor LT...
February 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/26676332/prolonged-tp-e-interval-tp-e-qt-ratio-and-tp-e-qtc-ratio-in-patients-with-type-2-diabetes-mellitus
#17
Alptug Tokatli, Fethi Kiliçaslan, Metin Alis, Omer Yiginer, Mehmet Uzun
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with increased risk of malignant ventricular arrhythmias. Cardiac electrical inhomogeneity may be the leading cause of the increased arrhythmic risk in patients with T2DM. The peak and the end of the T wave (Tp-e) interval and associated Tp-e/QT ratio are promising measures of ventricular repolarization indicating transmural dispersion of repolarization. The aim of this study was to assess ventricular repolarization in patients with T2DM by using Tp-e interval, Tp-e/QT ratio and Tp-e/corrected QT interval (QTc) ratio...
March 2016: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/26465871/evaluation-of-electrocardiographic-t-peak-to-t-end-interval-in-subjects-with-increased-epicardial-fat-tissue-thickness
#18
Ozgur Kaplan, Ertugrul Kurtoglu, Gokay Nar, Erdogan Yasar, Gokhan Gozubuyuk, Cem Dogan, Ahmet Ugur Boz, Sıho Hidayet, Hasan Pekdemir
BACKGROUND: The association between periatrial adiposity and atrial arrhythmias has been shown in previous studies. However, there are not enough available data on the association between epicardial fat tissue (EFT) thickness and parameters of ventricular repolarization. Thus, we aimed to evaluate the association of EFT thickness with indices of ventricular repolarization by using T-peak to T-end (Tp-e) interval and Tp-e/QT ratio. METHODS: The present study included 50 patients whose EFT thickness ≥ 9 mm (group 1) and 40 control subjects with EFT thickness < 9 mm (group 2)...
December 2015: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/26410545/the-t-peak-t-end-interval-as-a-marker-of-repolarization-abnormality-a-comparison-with-the-qt-interval-for-five-different-drugs
#19
Tanveer A Bhuiyan, Claus Graff, Jørgen K Kanters, Jimmi Nielsen, Jacob Melgaard, Jørgen Matz, Egon Toft, Johannes J Struijk
BACKGROUND AND OBJECTIVE: The T-peak to T-end (TpTe) interval has been suggested as an index of transmural dispersion and as a marker of drug-induced abnormal repolarization. In this study, we investigate the relation between TpTe and the QT interval. METHODS: Electrocardiograms (ECGs) from five different drugs (sotalol, sertindole, moxifloxacin, nalmefene, and Lu 38-135) and from a placebo group were analyzed. Semi-automatic measurements of T-peak, T-end, and QRS onset were obtained...
November 2015: Clinical Drug Investigation
https://www.readbyqxmd.com/read/26209300/assessment-of-electrocardiographic-parameters-in-patients-with-electrocution-injury
#20
Mehmet Baran Karataş, Tolga Onuk, Barış Güngör, Göktürk İpek, Kazım Serhan Özcan, Mustafa Kaplangöray, Yiğit Çanga, Gündüz Durmuş, Yasin Çakıllı, Osman Bolca
BACKGROUND: Electrocution injury (EI) is a major problem in developing countries. The aim of this study is to investigate the effect of EI on electrocardiographic (ECG) parameters. METHODS: A total of 43 patients hospitalized with diagnosis of EI were prospectively enrolled. Admission ECGs were compared with follow-up ECGs obtained one month after the event. RESULTS: Maximum P wave duration (Pmax), minimum P wave duration (Pmin), P wave dispersion (PWD), PR interval, QRS complex duration, corrected QT duration (QTc), QT dispersion (QTD), T peak to T end (Tp-e) interval were longer and Tp-e interval/QT and Tp-e interval/QTc ratios were higher on admission ECGs compared to follow-up ECGs...
September 2015: Journal of Electrocardiology
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