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https://www.readbyqxmd.com/read/27909408/reliability-validity-and-usefulness-of-30-15-intermittent-fitness-test-in-female-soccer-players
#1
Nedim Čović, Eldin Jelešković, Haris Alić, Izet Rađo, Erduan Kafedžić, Goran Sporiš, Daniel T McMaster, Zoran Milanović
PURPOSE: The aim of this study was to examine the reliability, validity and usefulness of the 30-15IFT in competitive female soccer players. METHODS: Seventeen elite female soccer players participated in the study. A within subject test-retest study design was utilized to assess the reliability of the 30-15 intermittent fitness test (IFT). Seven days prior to 30-15IFT, subjects performed a continuous aerobic running test (CT) under laboratory conditions to assess the criterion validity of the 30-15IFT. End running velocity (VCT and VIFT), peak heart rate (HRpeak) and maximal oxygen consumption (VO2max) were collected and/or estimated for both tests...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27905008/feasibility-and-accuracy-of-gated-blood-pool-spect-equilibrium-radionuclide-ventriculography-for-the-assessment-of-left-and-right-ventricular-volumes-and-function-in-patients-with-left-ventricular-assist-devices
#2
Olivier Lairez, Clément Delmas, Pauline Fournier, Emmanuelle Cassol, Simon Méjean, Pierre Pascal, Antoine Petermann, Camille Dambrin, Vincent Minville, Didier Carrié, Hervé Rousseau, Michel Galinier, Jérôme Roncalli, Bertrand Marcheix, Isabelle Berry
BACKGROUND: Left ventricular assist devices (LVADs) require serial assessment of right and left ventricular (RV & LV) volumes and function. Because the RV is not assisted, its function is a critical determinant of the hemodynamic and contributes significantly to postoperative morbidity and mortality. We evaluated the feasibility and the accuracy of tomographic-equilibrium radionuclide ventriculography (t-ERV) for the assessment of patients with LVADs. METHODS: Twenty-four patients with LVAD underwent t-ERV...
November 30, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27904512/evaluation-of-inhomogeneities-of-repolarization-in-patients-with-psoriasis-vulgaris
#3
Korhan Soylu, Sinan İnci, Gökhan Aksan, Gökay Nar, Esra Pancar Yüksel, Hande Serra Ocal, Mustafa Çapraz, Serkan Yüksel, Mahmut Şahin
INTRODUCTION: The arrhythmia potential has not been investigated adequately in psoriatic patients. In this study, we assessed the ventricular repolarization dispersion, using the Tp-e interval and the Tp-e/QT ratio, and investigated the association with inflammation. MATERIAL AND METHODS: Seventy-one psoriasis vulgaris patients and 70 age- and gender-matched healthy individuals were enrolled in the study. The severity of the disease was calculated using Psoriasis Area and Severity Index scoring...
December 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27889043/pr-interval-components-and-atrial-fibrillation-risk-from-the-atherosclerosis-risk-in-communities-study
#4
Justin W Smith, Wesley T O'Neal, M Benjamin Shoemaker, Lin Y Chen, Alvaro Alonso, S Patrick Whalen, Elsayed Z Soliman
Reports on the association between the PR-interval and atrial fibrillation (AF) are conflicting. We hypothesized that inconsistencies stem from that fact that the PR-interval represents a composite of several distinct components. We examined the associations of the PR-interval and its components (P-wave onset to P-wave peak duration, P-wave peak to P-wave end duration, and PR-segment) with incident AF in 14,924 participants (mean age 54 ± 5.8 years; 26% black; 55% women) from the Atherosclerosis Risk In Communities study...
November 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27874027/circulating-long-non-coding-rnas-as-biomarkers-of-left-ventricular-diastolic-function-and-remodelling-in-patients-with-well-controlled-type-2-diabetes
#5
D de Gonzalo-Calvo, F Kenneweg, C Bang, R Toro, R W van der Meer, L J Rijzewijk, J W Smit, H J Lamb, V Llorente-Cortes, T Thum
Contractile dysfunction is underdiagnosed in early stages of diabetic cardiomyopathy. We evaluated the potential of circulating long non-coding RNAs (lncRNAs) as biomarkers of subclinical cardiac abnormalities in type 2 diabetes. Forty-eight men with well-controlled type 2 diabetes and 12 healthy age-matched volunteers were enrolled in the study. Left ventricular (LV) parameters were measured by magnetic resonance imaging. A panel of lncRNAs was quantified in serum by RT-qPCR. No differences in expression levels of lncRNAs were observed between type 2 diabetes patients and healthy volunteers...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27846395/mid-term-functional-outcome-of-a-total-arthroplasty-of-the-first-metatarsophalangeal-joint
#6
Corina Nüesch, Annegret Mündermann, Monika Horisberger
BACKGROUND: Arthroplasty of the first metatarsophalangeal joint is an alternative treatment option for end-stage hallux rigidus to the current gold standard of arthrodesis. The aim of this study was to investigate the mid-term functional outcome of an anatomically shaped prosthesis for the first metatarsophalangeal joint using pedobarography. METHODS: Ten patients (12 affected feet; age at surgery: 62.1 (SD: 7.2) years) were investigated preoperatively and 52 (SD: 3) months postoperatively using pedobarography (EMED, novel GmbH, Munich, Germany)...
November 10, 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/27826337/the-relationship-between-angiotensin-ii-type-1-receptor-gene-polymorphism-and-repolarization-parameters-after-a-first-anterior-acute-myocardial-infarction
#7
Onder Ozturk, Unal Ozturk, Sebnem Nergiz, M Zulkif Karahan
BACKGROUND AND OBJECTIVES: Genetic influence on T-wave peak to End (Tpe) time in patients with a first anterior acute myocardial infarction (AMI) is uncertain. A polymorphism in the angiotensin-II type 1 receptor (AT1R) gene was discovered recently. The polymorphism consists of an A or C variant, given three different possible genotypes: AA, AC, CC. The purpose of this study was to determine the effects of polymorphism of the AT1R gene polymorphism on Tpe after a first anterior AMI. SUBJECTS AND METHODS: The subjects were 142 patients (110 men, 32 women, 58±13 years) with a first anterior AMI; ten patients were excluded from this study...
November 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27824660/establishment-of-a-national-cervical-screening-programme-in-ireland-cervicalcheck-the-first-6-years
#8
Gráinne M Flannelly, Marie T Mooney, Gráinne M Greehy, Eoin B Keogh, Sara A McNally, Patricia E Fitzpatrick
The national cervical screening programme, CervicalCheck, commenced in Ireland in 2008. Free cervical smear tests are offered to over 1.2 million women aged 25-60 every 3 (aged 25-44) and 5 (aged 45-60) years. The purpose of this paper is to highlight the achievements and document the experience of the first 6 years of a new cervical screening programme. Data were extracted from the programme screening register and colposcopy management systems. SAS, version 9.4 was used for statistical analysis. Over 1.98 million smear tests were performed in over 1 million women during the first 6 years of the programme...
November 7, 2016: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27801878/air-pollution-exposure-in-relation-to-the-commute-to-school-a-bradford-uk-case-study
#9
Kim N Dirks, Judith Y T Wang, Amirul Khan, Christopher Rushton
Walking School Buses (WSBs) provide a safe alternative to being driven to school. Children benefit from the contribution the exercise provides towards their daily exercise target, it gives children practical experience with respect to road safety and it helps to relieve traffic congestion around the entrance to their school. Walking routes are designed largely based in road safety considerations, catchment need and the availability of parent support. However, little attention is given to the air pollution exposure experienced by children during their journey to school, despite the commuting microenvironment being an important contributor to a child's daily air pollution exposure...
October 29, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27798210/solithromycin-a-novel-macrolide-does-not-prolong-cardiac-repolarization-a-randomized-three-way-crossover-study-in-healthy-subjects
#10
Borje Darpo, Philip T Sager, Prabhavathi Fernandes, Brian D Jamieson, Kara Keedy, Meijian Zhou, David Oldach
BACKGROUND: Macrolide antibiotics may cause QT prolongation. OBJECTIVES: To study the QT effect of a novel macrolide, solithromycin. METHODS: This was a thorough QT study with a three-way crossover design performed in healthy male and female subjects to evaluate the ECG effects of a novel macrolide, solithromycin. Forty-eight subjects were randomized to receive 800 mg of intravenous (iv) solithromycin, 400 mg of oral moxifloxacin and placebo in three separate treatment periods...
October 26, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27795368/safety-tolerability-and-pharmacokinetics-of-medi4893-an-investigational-extendedhalf-life-anti-staphylococcus-aureus-alpha-toxin-human-monoclonal-antibody-in-healthy-adults
#11
Xiang-Qing Yu, Gabriel J Robbie, Yuling Wu, Mark T Esser, Kathryn Jensen, Howard I Schwartz, Terramika Bellamy, Martha Hernandez-Illas, Hasan S Jafri
MEDI4893 is an investigational immunoglobulin G1K monoclonal antibody that specifically binds to and neutralizes alpha-toxin, a key Staphylococcus aureus virulence factor. A triple-amino acid substitution, M252Y/S254T/T256E, was engineered into the MEDI4893 Fc region to extend its serum half-life. A phase 1, double-blind, dose escalation study was designed to evaluate the safety, tolerability, pharmacokinetics, anti-alpha-toxin neutralizing activity, and anti-drug antibody (ADA) response of MEDI4893 following a single intravenous infusion in healthy adults 18-65 years of age...
October 17, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27785856/minimal-t-wave-representation-and-its-use-in-the-assessment-of-drug-arrhythmogenicity
#12
Saeed Shakibfar, Claus Graff, Jørgen K Kanters, Jimmi Nielsen, Samuel Schmidt, Johannes J Struijk
BACKGROUND: Recently, numerous models and techniques have been developed for analyzing and extracting features from the T wave which could be used as biomarkers for drug-induced abnormalities. The majority of these techniques and algorithms use features that determine readily apparent characteristics of the T wave, such as duration, area, amplitude, and slopes. METHODS: In the present work the T wave was down-sampled to a minimal rate, such that a good reconstruction was still possible...
October 27, 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/27738517/combined-biomarker-testing-for-the-prediction-of-left-ventricular-remodelling-in-st-elevation-myocardial-infarction
#13
Sebastian Johannes Reinstadler, Hans-Josef Feistritzer, Martin Reindl, Gert Klug, Agnes Mayr, Johannes Mair, Werner Jaschke, Bernhard Metzler
OBJECTIVE: The utility of different biomarkers for the prediction of left ventricular remodelling (LVR) following ST-elevation myocardial infarction (STEMI) has been evaluated in several studies. However, very few data exist on the prognostic value of combined biomarkers. The aim of this study was to comprehensively investigate the prognostic value for LVR of routinely available biomarkers measured after reperfused STEMI. METHODS: Serial measurements of N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity cardiac troponin T (hs-cTnT), aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and high-sensitivity C reactive protein (hs-CRP) were performed in 123 patients with STEMI treated with primary percutaneous coronary intervention in this prospective observational study...
2016: Open Heart
https://www.readbyqxmd.com/read/27702850/traditional-and-novel-electrocardiographic-conduction-and-repolarization-markers-of-sudden-cardiac-death
#14
Gary Tse, Bryan P Yan
Sudden cardiac death, frequently due to ventricular arrhythmias, is a significant problem globally. Most affected individuals do not arrive at hospital in time for medical treatment. Therefore, there is an urgent need to identify the most-at-risk patients for insertion of prophylactic implantable cardioverter defibrillators. Clinical risk markers derived from electrocardiography are important for this purpose. They can be based on repolarization, including corrected QT (QTc) interval, QT dispersion (QTD), interval from the peak to the end of the T-wave (Tpeak - Tend), (Tpeak - Tend)/QT, T-wave alternans (TWA), and microvolt TWA...
October 4, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27697254/comparison-of-different-types-of-phacoemulsification-tips-i-quantitative-analysis-of-elemental-composition-and-tip-surface-microroughness
#15
Konstantinos T Tsaousis, Liliana Werner, Jesus Paulo Perez, He J Li, Nicholas Reiter, Jia J Guan, Nick Mamalis
PURPOSE: To evaluate the elemental composition of phacoemulsification tips and their surface roughness in the microscale. SETTING: John A. Moran Eye Center and Utah Nanofab, College of Engineering, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: Seven types of phacoemulsification tips were studied. The phaco tips were examined through energy-dispersive x-ray spectroscopy (EDS) and x-ray photoelectron spectroscopy (XPS) for elemental composition...
September 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27693032/an-endovascular-model-of-ischemic-myopathy-from-peripheral-arterial-disease
#16
Chandler A Long, Lucas H Timmins, Panagiotis Koutakis, Traci T Goodchild, David J Lefer, Iraklis I Pipinos, George P Casale, Luke P Brewster
OBJECTIVE: Peripheral arterial disease (PAD) is a significant age-related medical condition with limited pharmacologic options. Severe PAD, termed critical limb ischemia, can lead to amputation. Skeletal muscle is the end organ most affected by PAD, leading to ischemic myopathy and debility of the patient. Currently, there are not any therapeutics to treat ischemic myopathy, and proposed biologic agents have not been optimized owing to a lack of preclinical models of PAD. Because a large animal model of ischemic myopathy may be useful in defining the optimal dosing and delivery regimens, the objective was to create and to characterize a swine model of ischemic myopathy that mimics patients with severe PAD...
September 29, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27670068/canine-pulmonary-vein-to-pulmonary-artery-ratio-echocardiographic-technique-and-reference-intervals
#17
F Birettoni, D Caivano, V Patata, N S Moïse, C Guglielmini, M Rishniw, F Porciello
OBJECTIVES: The size of the pulmonary veins (PVs) and pulmonary arteries (PAs) changes in response to hemodynamic alterations caused by physiological events and disease. We sought to create standardized echocardiographic methods for imaging the right ostium of the pulmonary veins (RPVs) and the right pulmonary artery (RPA) using specific landmarks and timing to quantify vessel diameters and phasic changes during the cardiac cycle. ANIMALS: Fifty client-owned healthy dogs prospectively recruited...
September 23, 2016: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/27669194/vertical-and-horizontal-impact-force-comparison-during-jump-landings-with-and-without-rotation-in-ncaa-division-1-male-soccer-players
#18
John R Harry, Leland A Barker, John A Mercer, Janet S Dufek
There is a wealth of research on impact force characteristics when landing from a jump. However, there are no data on impact forces during landing from a jump with an airborne rotation about the vertical axis. We examined impact force parameters in the vertical and horizontal axes during vertical jump (VJ) landings and vertical jump landings with a 180-degree rotation (VJR). Twenty-four Division 1 male soccer players performed three VJ and VJR landings on a dual-force platform system. Paired-samples t-tests (α=0...
September 22, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27660578/surface-electrocardiogram-predictors-of-sudden-cardiac-arrest
#19
REVIEW
Samy A Abdelghani, Todd M Rosenthal, Daniel P Morin
BACKGROUND: Heart disease is a major cause of death in industrialized nations, with approximately 50% of these deaths attributable to sudden cardiac arrest. If patients at high risk for sudden cardiac arrest can be identified, their odds of surviving fatal arrhythmias can be significantly improved through prophylactic implantable cardioverter defibrillator placement. This review summarizes the current knowledge pertaining to surface electrocardiogram (ECG) predictors of sudden cardiac arrest...
2016: Ochsner Journal
https://www.readbyqxmd.com/read/27645491/neopuff-t-piece-resuscitator-does-device-design-affect-delivered-ventilation
#20
Murray Hinder, Pranav Jani, Archana Priyadarshi, Alistair McEwan, Mark Tracy
BACKGROUND: The T-piece resuscitator (TPR) is in common use worldwide to deliver positive pressure ventilation during resuscitation of infants <10 kg. Ease of use, ability to provide positive end-expiratory pressure (PEEP), availability of devices inbuilt into resuscitaires and cheaper disposable options have increased its popularity as a first-line device for term infant resuscitation. Research into its ventilation performance is limited to preterm infant and animal studies. Efficacy of providing PEEP and the use of TPR during term infant resuscitation are not established...
September 19, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
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