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https://www.readbyqxmd.com/read/29692221/temporal-trends-in-secondary-prevention-in-myocardial-infarction-patients-discharged-with-left-ventricular-systolic-dysfunction-in-poland
#1
Mariusz Gasior, Marek Gierlotka, Łukasz Pyka, Tomasz Zdrojewski, Bogdan Wojtyniak, Krzysztof Chlebus, Piotr Rozentryt, Jacek Niedziela, Piotr Jankowski, Jadwiga Nessler, Grzegorz Opolski, Piotr Hoffman, Ewa Jankowska, Lech Polonski, Piotr Ponikowski
Background The proportion of patients discharged after myocardial infarction with left ventricular systolic dysfunction remains high and the prognosis is unfavourable. The aim of this study was to analyse the temporal trends in the treatment and outcomes of a nationwide cohort of patients. Methods and results Data from the Polish Registry of Acute Coronary Syndromes and Acute Myocardial Infarction in Poland Registry were combined to achieve complete information on inhospital course, treatment and outcomes. An all-comer population of patients discharged with left ventricular ejection fraction of 40% or less formed the sample population ( n = 28,080)...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29691803/association-of-beta-blockers-with-survival-on-patients-presenting-with-acs-treated-with-pci-a-propensity-score-analysis-from-the-bleemacs-registry
#2
Fabrizio D'Ascenzo, Dario Celentani, Alessandro Brustio, Alberto Grosso, Sergio Raposeiras-Roubín, Emad Abu-Assi, Jose Paulo Simao Henriques, Jorge Saucedo, José Ramón González-Juanatey, Stephen B Wilton, Wouter J Kikkert, Iván Nuñez-Gil, Albert Ariza-Sole, Xiantao Song, Dimitrios Alexopoulos, Christoph Liebetrau, Tetsuma Kawaji, Zenon Huczek, Shao-Ping Nie, Toshiharu Fujii, Luis Correia, Masa-Aki Kawashiri, José María García-Acuña, Danielle Southern, Emilio Alfonso, Belén Terol, Alberto Garay, Dongfeng Zhang, Yalei Chen, Ioanna Xanthopoulou, Neriman Osman, Helge Möllmann, Hiroki Shiomi, Michal Kowara, Krzysztof Filipiak, Xiao Wang, Yan Yan, Jing-Yao Fan, Yuji Ikari, Takuya Nakahayshi, Kenji Sakata, Masakazu Yamagishi, Oliver Kalpak, Sasko Kedev, Claudio Moretti, Maurizio D'Amico, Fiorenzo Gaita
PURPOSE: The aim was to evaluate prognostic value of beta-blocker (BB) administration in acute coronary syndromes (ACS) patients in the percutaneous coronary intervention (PCI) era. METHODS AND RESULTS: The BleeMACS project is a multicenter, observational, retrospective registry enrolling patients with ACS worldwide in 15 hospitals. Patients discharged with BB therapy were compared to those discharged without a BB before and after propensity score with matching...
April 24, 2018: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/29691643/the-relationship-between-timing-of-prasugrel-pretreatment-and-in-stent-thrombus-immediately-after-percutaneous-coronary-intervention-for-acute-coronary-syndrome-an-optical-coherence-tomography-study
#3
Yosuke Katayama, Takashi Kubo, Yasushi Ino, Takeyoshi Kameyama, Yoshiki Matsuo, Hironori Kitabata, Kosei Terada, Hiroki Emori, Hiroshi Aoki, Akira Taruya, Kunihiro Shimamura, Shingo Ota, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka
The optimal timing of pretreatment with prasugrel in percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) is unclear. We used optical coherence tomography (OCT) to compare in-stent thrombus volume immediately after PCI between the administration of low-dose prasugrel (20 mg loading dose) at the time of diagnosis of ACS (early prasugrel: n = 34) and the administration of low-dose prasugrel immediately after diagnostic angiography prior to PCI for ACS (late prasugrel: n = 56). The durations between the administration of prasugrel and OCT in the early prasugrel group and late prasugrel group were 5...
April 24, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29691183/intravascular-imaging-for-cardiac-arrest-with-normal-coronary-arteriography
#4
Tawfiq Choudhury, Amir Solomonica, Rodrigo Bagur, Shahar Lavi
Spontaneous coronary artery dissection (SCAD) is an under-recognised presentation of acute coronary syndrome. A high index of suspicion is essential. If diagnostic doubt is high, intracoronary imaging, performed carefully, can be useful, although it can result in worsening of the clinical condition. The current report exemplifies the complexity of diagnosis and management of SCAD in a patient with out-of-hospital cardiac arrest and non-diagnostic angiography.
April 14, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29687656/cha-2-ds-2-vasc-score-and-clinical-outcomes-of-patients-with-chest-pain-discharged-from-internal-medicine-wards-following-acute-coronary-syndrome-rule-out
#5
Guy Topaz, Ory Haisraely, Yacov Shacham, Gil Beery, Lotan Shilo, Nuha Kassem, David Pereg, Yona Kitay-Cohen
BACKGROUND: Chest-pain patients deemed safe for discharge from internal medicine wards might still be at risk for adverse outcomes. HYPOTHESIS: CHA2 DS2 -VASc score improves risk stratification of low-risk chest-pain patients discharged after acute coronary syndrome (ACS) rule-out. METHODS: We accessed medical records of patients who were admitted to internal medicine wards at a single medical center during 2010-2016 and discharged following an ACS rule-out...
April 23, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29685372/emergency-physician-risk-estimates-and-admission-decisions-for-chest-pain-a-web-based-scenario-study
#6
David L Schriger, Michael Menchine, Warren Wiechmann, Guy Carmelli
STUDY OBJECTIVE: We conducted this study to better understand how emergency physicians estimate risk and make admission decisions for patients with low-risk chest pain. METHODS: We created a Web-based survey consisting of 5 chest pain scenarios that included history, physical examination, ECG findings, and basic laboratory studies, including a negative initial troponin-level result. We administered the scenarios in random order to emergency medicine residents and faculty at 11 US emergency medicine residency programs...
April 20, 2018: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29685010/expressions-and-clinical-significance-of-factors-related-to-acute-coronary-syndrome
#7
H Sun, J Zhang, Y Zheng, S Shang
Acute coronary syndrome (ACS) is the acute stage of coronary artery disease, which remains a major cause of mortality and morbidity. It is essential to explore the role of matrix metalloproteinase -2 (MMP-2) and interleukin (IL)-18 and their association with disease in patients with severe ACS. Circulating MMP-2 and IL-18 levels were measured using enzyme linked immunosorbent assay (ELISA) in 94 subjects with acute coronary syndrome (ACS, n=38), stable angina pectoris (SAP, n=27) and healthy individuals (control group, n=29)...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29684934/-optimal-medical-therapy-and-secondary-prevention-in-patients-after-an-acute-coronary-syndrome
#8
Barbara E Stähli, Ulf Landmesser
Antithrombotic therapy and other secondary preventive measures such as lifestyle changes, lipid lowering and blood pressure control, along with coronary revascularization strategies, can markedly improve clinical outcomes in patients after an acute coronary syndrome. Current guideline-recommended secondary preventive measures in patients with a recent acute coronary syndrome event according to the European Society of Cardiology (ESC) are summarized in this review.
May 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29684928/-63-year-old-patient-with-acute-dyspnoea-in-acute-coronary-syndrome
#9
Guido Michels, Roman Pfister, Christopher Hohmann
No abstract text is available yet for this article.
May 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29682358/acute-pericarditis-occurring-three-days-after-intravesical-instillation-of-mitomycin-c-after-transurethral-bladder-tumor-resection-in-a-64-year-old-woman
#10
Vineet Meghrajani, Arsalan Hashmi, Shuo Cheng Lin, Zvi Plawes, Shelly Brejt
We present a 64-year-old woman who developed symptoms of acute pericarditis three days after undergoing intravesical instillation of mitomycin C following transurethral bladder tumor resection. Mitomycin C is a chemotherapeutic agent which acts by alkylation of DNA and is known to be cardiotoxic when systemically administered. Despite classic pericarditis symptoms, the patient underwent an urgent coronary angiogram due to elevated cardiac troponin I level, EKG changes, and wall motion abnormalities on her echocardiogram...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29682142/left-ventricular-hydatid-cyst-mimicking-acute-coronary-syndrome
#11
Ali Fuat Tekin, Mehmet Sedat Durmaz, Mustafa Dağli, Sahabettin Akbayrak, Pelin Akbayrak, Bekir Turgut
Hydatid disease is caused by the larvae of Echinococcus granulosus . Domestic dogs and cats are the primary carriers of echinococcal organisms. In some particular regions of the world, this parasitic infection is still endemic. Despite the fact that hydatid disease is most frequently located in the liver (50%-70% of cases) and the lungs (20%-30% of cases), it can occur in any organ or tissue. However, intracardiac localization of hydatid cyst is very rare and it is found in less than 2% of the cases. Cardiac involvement can be caused by systemic or pulmonary circulation or direct spread from adjacent structures...
June 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29681571/the-outcome-of-percutaneous-coronary-intervention-for-significant-atherosclerotic-lesions-in-segment-proximal-to-myocardial-bridge-at-left-anterior-descending-coronary-artery
#12
Zhang Hao, Jia Xinwei, Zakarya Ahmed, Pan Huanjun, Wang Zhanqi, Wang Yanfei, Chen Chunhong, Zhang Chan, Fu Liqiang
This study aimed to evaluate the efficacy of percutaneous coronary intervention (PCI) for significant atherosclerosis lesions proximal to myocardial bridge (MB) at left anterior descending coronary artery (LAD).A total of 330 consecutive patients with LAD significant stenosis, diagnosed as acute coronary syndrome (ACS), were included. Based on whether combined with MB, the patients were divided into the MB group (MB, n = 48) and non-MB group (NMB, n = 282). Drug eluting stents (DES) were successfully implanted in the stenostic segments prior to MB...
April 20, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29680822/disparities-in-the-estimation-of-glomerular-filtration-rate-according-to-cockcroft-gault-modification-of-diet-in-renal-disease-4-and-chronic-kidney-disease-epidemiology-collaboration-equations-and-relation-with-outcomes-in-patients-with-acute-coronary-syndrome
#13
José Miguel Rivera-Caravaca, Juan Miguel Ruiz-Nodar, Antonio Tello-Montoliu, María Asunción Esteve-Pastor, Miriam Quintana-Giner, Andrea Véliz-Martínez, Esteban Orenes-Piñero, Ana Isabel Romero-Aniorte, Nuria Vicente-Ibarra, Vicente Pernias-Escrig, Luna Carrillo-Alemán, Elena Candela-Sánchez, Ignacio Hortelano, Beatriz Villamía, Miriam Sandín-Rollán, Laura Nuñez-Martínez, Mariano Valdés, Francisco Marín
BACKGROUND: A simple method to assess renal function is the estimated glomerular filtration rate, and it shows prognostic implications. However, it remains unknown which equation should be used in patients with acute coronary syndrome. We compared the ability and correlation of the Cockcroft-Gault, Modification of Diet in Renal Disease-4 (MDRD-4), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations and their predictive performance for major adverse cardiovascular events, all-cause mortality, and major bleeding in a cohort of patients with acute coronary syndrome...
April 21, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29680187/clinical-characteristics-and-prognosis-of-very-elderly-patients-with-acute-coronary-syndrome-treated-with-ticagrelor-insights-from-the-longevo-sca-registry
#14
Albert Ariza-Solé, Francesc Formiga, Alfredo Bardají, Ana Viana-Tejedor, Oriol Alegre, Fernando de Frutos
No abstract text is available yet for this article.
April 18, 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29679162/circulating-troponin-i-level-in-patients-with-acute-ischemic-stroke
#15
REVIEW
Jacob VanHouten, Gregory Fricker, Bridget Collins, Ritwik Bhatia, Christopher Ellis, Matthew Schrag
PURPOSE OF REVIEW: Cardiac troponin levels in the blood are an important biomarker of acute coronary events, but may also be elevated in the context of acute ischemic stroke without an obvious concurrent myocardial insult. The objective of this study and systematic review is to determine how high the circulating troponin I level can rise due to ischemic stroke. RECENT FINDINGS: Anonymized medical records from Vanderbilt University Medical Center were reviewed identifying 151,972 unique acute ischemic stroke events, of which 1226 met criteria for inclusion in this study...
April 20, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29678337/relation-of-coronary-culprit-lesion-morphology-determined-by-optical-coherence-tomography-and-cardiac-outcomes-to-serum-uric-acid-levels-in-patients-with-acute-coronary-syndrome
#16
Nobuaki Kobayashi, Noritake Hata, Masafumi Tsurumi, Yusaku Shibata, Hirotake Okazaki, Akihiro Shirakabe, Masamichi Takano, Yoshihiko Seino, Wataru Shimizu
The aims of the present study were to elucidate features of culprit lesion plaque morphology using optical coherence tomography (OCT) in relation to elevated serum uric acid (sUA) levels and to clarify the impact of sUA levels on adverse clinical outcomes in patients with acute coronary syndrome (ACS). Clinical data and outcomes were compared between ACS patients with sUA ≥6 mg/dl (high-sUA; n = 506) and sUA <6.0 mg/dl (low-sUA; n = 608). Angiography and OCT findings were analyzed in patients with preintervention OCT and compared between groups of high-sUA (n = 206) and low-sUA (n = 273)...
March 28, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29677409/is-there-an-association-between-heparin-induced-thrombocytopenia-hit-and-autoimmune-disease
#17
Brent Klinkhammer, Michael Gruchalla
BACKGROUND: Heparin-induced thrombocytopenia (HIT) is a drug-induced, immunoglobulin G medicated autoimmune disorder associated with several negative clinical outcomes including increased morbidity, mortality, and increased medical costs. Previous studies have shown associations between comorbid autoimmune diseases, but there is little known about associations between HIT and autoimmunity. PURPOSE: To provide clinical data to suggest an association between HIT and autoimmunity...
March 2018: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29675278/adrenocorticotropic-hormone-secreting-pheochromocytoma-underlying-glucocorticoid-induced-pheochromocytoma-crisis
#18
Gil A Geva, David J Gross, Haggi Mazeh, Karine Atlan, Iddo Z Ben-Dov, Matan Fischer
Context: Pheochromocytomas are hormone secreting tumors of the medulla of the adrenal glands found in 0.1-0.5% of patients with hypertension. The vast majority of pheochromocytomas secrete catecholamines, but they have been occasionally shown to also secrete interleukins, calcitonin, testosterone, and in rare cases adrenocorticotropic hormone. Pheochromocytoma crisis is a life threatening event in which high levels of catecholamines cause a systemic reaction leading to organ failure. Case Description: A 70-year-old man was admitted with acute myocardial ischemia following glucocorticoid administration as part of an endocrine workup for an adrenal mass...
2018: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/29675258/livedo-reticularis-a-cutaneous-clue-to-an-underlying-endocrine-crisis
#19
Natasha Shrikrishnapalasuriyar, Mirena Noyvirt, Philip Evans, Bethan Gibson, Elin Foden, Atul Kalhan
A 54-year-old woman was admitted to hospital with a presumed allergic reaction to a single dose of amoxicillin given for a suspected upper respiratory tract infection. She complained of chest tightness although there was no wheeze or stridor. On examination, she was pyrexial, tachycardic, hypertensive and had a diffuse mottled rash on her lower limbs. Her initial investigations showed raised inflammatory markers. She was treated in the intensive care for a presumed anaphylactic reaction with an underlying sepsis...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29673505/influence-of-microcirculatory-dysfunction-on-angiography-based-functional-assessment-of-coronary-stenoses
#20
Hernán Mejía-Rentería, Joo Myung Lee, Francesco Lauri, Nina W van der Hoeven, Guus A de Waard, Fernando Macaya, María José Pérez-Vizcayno, Nieves Gonzalo, Pilar Jiménez-Quevedo, Luis Nombela-Franco, Pablo Salinas, Iván Núñez-Gil, María Del Trigo, Sonoka Goto, Hyun Jong Lee, Catherine Liontou, Antonio Fernández-Ortiz, Carlos Macaya, Niels van Royen, Bon-Kwon Koo, Javier Escaned
OBJECTIVES: The authors sought to evaluate the influence of coronary microcirculatory dysfunction (CMD) on the diagnostic performance of the quantitative flow ratio (QFR). BACKGROUND: Functional angiographic assessment of coronary stenoses based on fluid dynamics, such as QFR, constitutes an attractive alternative to fractional flow reserve (FFR). However, it is unknown whether CMD affects the reliability of angiography-based functional indices. METHODS: FFR and the index of microcirculatory resistance (IMR) were measured in 300 vessels (248 patients) as part of a multicenter international registry...
April 23, 2018: JACC. Cardiovascular Interventions
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