keyword
MENU ▼
Read by QxMD icon Read
search

coronary acute syndrome

keyword
https://www.readbyqxmd.com/read/29907395/comparison-of-clinical-risk-scores-for-triaging-high-risk-chest-pain-patients-at-the-emergency-department
#1
Salah S Al-Zaiti, Ziad Faramand, Mohammad O Alrawashdeh, Susan M Sereika, Christian Martin-Gill, Clifton Callaway
BACKGROUND: Many of the clinical risk scores routinely used for chest pain assessment have not been validated in patients at high risk for acute coronary syndrome (ACS). We performed an independent comparison of HEART, TIMI, GRACE, FRISC, and PURSUIT scores for identifying chest pain due to ACS and for predicting 30-day death or re-infarction in patients arriving through Emergency Medical Services (EMS). METHODS AND RESULTS: We enrolled consecutive EMS patients evaluated for chest pain at three emergency departments...
June 8, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29907160/non-culprit-plaque-characteristics-in-acute-coronary-syndrome-patients-with-raised-hemoglobina1c-an-intravascular-optical-coherence-tomography-study
#2
Shaotao Zhang, Jiannan Dai, Haibo Jia, Sining Hu, Hongwei Du, Ning Li, Yongpeng Zou, Yanan Zou, Shenhong Jing, Yan Wang, Rong Sun, Bo Yu
BACKGROUND: Raised hemoglobinA1c (HbA1c) is an indicator of pre-diabetes, which is associated with increased risk of coronary artery disease. However, the detailed morphological characteristics of non-culprit plaques in acute coronary syndrome (ACS) patients remain largely unknown. METHODS: A total of 305 non-culprit plaques from 216 ACS patients were analyzed by intravascular optical coherence tomography. These patients were divided into three groups according to the serum glycosylated hemoglobin level: normal HbA1c (< 5...
June 15, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29906667/the-high-cost-of-critical-care-unit-over-utilization-for-patients-with-nste-acs
#3
Sean van Diepen, Dat T Tran, Justin A Ezekowitz, David A Zygun, Jason N Katz, Renato D Lopes, L Kristin Newby, Finlay A McAlister, Padma Kaul
BACKGROUND: There is substantial variability among hospitals in critical care unit (CCU) utilization for patients admitted with non-ST-Segment Elevation Acute Coronary Syndromes (NSTE ACS). We estimated the potential cost saving if all hospitals adopted low CCU utilization practices for patients with NSTE ACS. METHODS: National hospital claims data were used to identify all patients with a primary diagnosis of NSTE ACS initially admitted to an acute care hospital between 2007 and 2013...
May 19, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29906425/diastolic-hypotension-may-attenuate-benefits-from-intensive-systolic-targets-secondary-analysis-of-a-randomized-controlled-trial
#4
Todd C Lee, Rodrigo B Cavalcanti, Emily G McDonald, Louise Pilote, James M Brophy
BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT) was a randomized controlled trial which studied 9361 adults aged 50 and older with systolic blood pressure above 130mmHg and one or more cardiovascular risk factor. Patients were randomized to intensive (≤ 120mmHg) or standard (≤ 140mmHg) systolic targets. In August 2016, a limited dataset was released for secondary analysis. We hypothesized that excessive lowering of diastolic blood pressure could cause harm. Using the data from SPRINT, we sought to determine whether the development of diastolic hypotension during treatment was associated with adverse outcomes...
June 12, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29904459/unusual-presentation-of-spontaneous-coronary-artery-dissection-in-an-older-male
#5
Rajveer Joea, Sarah J Strube, Todd K Zynda
Spontaneous coronary artery dissection (SCAD) is a variant of acute coronary syndrome (ACS) that is poorly understood. SCAD has been linked to fibromuscular dysplasia (FMD), connective tissue disease (CTD), pregnancy and hormonal imbalance, systemic inflammatory conditions (e.g. IBD, vasculitis), and coronary artery vasospasm rather than traditional cardiac risk factors. Symptomology generally accompanying SCAD is indistinguishable from ACS making the timely recognition and diagnosis vital for prompt treatment...
June 2018: Cardiology Research
https://www.readbyqxmd.com/read/29904449/red-cell-distribution-width-and-mortality-in-patients-with-acute-coronary-syndrome-a-meta-analysis-on-prognosis
#6
Lauro L Abrahan, John Daniel A Ramos, Elleen L Cunanan, Marc Denver A Tiongson, Felix Eduardo R Punzalan
Background: Red cell distribution width (RDW), a routine component of the complete blood count (CBC), measures variation in the size of circulating erythrocytes. It has been associated with several clinical outcomes in cardiovascular disease. We sought to strengthen the association between RDW and mortality in patients admitted for acute coronary syndrome (ACS) by pooling together data from available studies. Methods: Studies that fulfilled the following were identified for analysis: 1) observational; 2) included patients admitted for ACS; 3) reported data on all-cause or cardiovascular (CV) mortality in association with a low or high RDW; and 4) used logistic regression analysis to control for confounders...
June 2018: Cardiology Research
https://www.readbyqxmd.com/read/29903845/adiponectin-free-fatty-acids-and-cardiovascular-outcomes-in-patients-with-type-2-diabetes-and-acute-coronary-syndrome
#7
Ilse C Schrieks, Anna Nozza, Barbara E Stähli, John B Buse, Robert R Henry, Klas Malmberg, Bruce Neal, Stephen J Nicholls, Lars Rydén, Linda Mellbin, Anders Svensson, Hans Wedel, Arlette Weichert, A Michael Lincoff, Jean-Claude Tardif, Diederick E Grobbee, Gregory G Schwartz
OBJECTIVE: In observational cohorts, adiponectin is inversely associated and free fatty acids (FFAs) are directly associated with incident coronary heart disease (CHD). Adiponectin tends to be reduced and FFAs elevated in type 2 diabetes. We investigated relationships of adiponectin and FFA and major adverse cardiovascular events (MACEs) and death in patients with acute coronary syndrome (ACS) and type 2 diabetes using data from the AleCardio trial, which compared the PPAR-α/γ agonist aleglitazar with placebo...
June 14, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29902700/ticagrelor-a-p2y12-antagonist-attenuates-vascular-dysfunction-and-inhibits-atherogenesis-in-apolipoprotein-e-deficient-mice
#8
Byambasuren Ganbaatar, Daiju Fukuda, Hotimah Masdan Salim, Sachiko Nishimoto, Kimie Tanaka, Yasutomi Higashikuni, Yoichiro Hirata, Shusuke Yagi, Takeshi Soeki, Masataka Sata
BACKGROUND AND AIMS: Ticagrelor reduces cardiovascular events in patients with acute coronary syndrome (ACS). Recent studies demonstrated the expression of P2Y12 on vascular cells including endothelial cells, as well as platelets, and suggested its contribution to atherogenesis. We investigated whether ticagrelor attenuates vascular dysfunction and inhibits atherogenesis in apolipoprotein E-deficient (apoe-/- ) mice. METHODS: Eight-week-old male apoe-/- mice were fed a western-type diet (WTD) supplemented with 0...
May 31, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29902156/hypertriglyceridemia-thalassemia-syndrome
#9
Mili Jain, Wahid Ali, Brijendra Bahadur Singh, Nishant Verma, Ashutosh Kumar
BACKGROUND: Hypertriglyceridemia thalassemia syndrome is a rare entity with an unknown pathogenetic link. CASE PRESENTATION: We report a case of an 8-month-old female with thalassemia major and increased triglyceride (TG) levels. The clinical features were as in classical thalassemia except for a white discoloration of the plasma. After exclusion of familial triglyceridemia and secondary causes (hypothyroidism, nephrotic syndrome, drugs etc.), a diagnosis of hypertriglyceridemia thalassemia syndrome was made...
June 14, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29901638/multiple-penetrating-aortic-ulcers-and-rupture-of-superior-mesenteric-artery-branch-presenting-with-symptoms-similar-to-unstable-angina-a-case-report
#10
Suqiao Zhang, Rui Lian, Guoqiang Zhang
RATINALE: Penetrating aortic ulcer (PAU) and rupture of a superior mesenteric artery branch is a rare but potentially life-threatening condition. PATIENT CONCERNS: We describe a case of 73-year-old man was brought to our Emergency Department for intermittent back pain. DIAGNOSES: The final diagnoses are PAU (Stanford B) and rupture of a branch of the superior mesenteric artery. INTERVENTIONS: Two covered stents were placed in the thoracic aorta and the right external iliac artery, and the superior mesenteric artery branch was embolized...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29898844/an-open-label-2-%C3%A3-2-factorial-randomized-controlled-trial-to-evaluate-the-safety-of-apixaban-vs-vitamin-k-antagonist-and-aspirin-vs-placebo-in-patients-with-atrial-fibrillation-and-acute-coronary-syndrome-and-or-percutaneous-coronary-intervention-rationale
#11
Renato D Lopes, Amit N Vora, Danny Liaw, Christopher B Granger, Harald Darius, Shaun G Goodman, Roxana Mehran, Stephan Windecker, John H Alexander
BACKGROUND: The optimal antithrombotic strategy for patients with atrial fibrillation (AF) who develop acute coronary syndrome (ACS) and/or the need for percutaneous coronary intervention (PCI) is uncertain. The risk of bleeding is a major concern when oral anticoagulation is required to prevent stroke, and concomitant therapy with antiplatelet agents is required to minimize recurrent ischemic events. DESIGN: AUGUSTUS is an international, multicenter randomized trial with a 2 × 2 factorial design to compare apixaban with vitamin K antagonists and aspirin with placebo in patients with AF who develop ACS and/or undergo PCI and are receiving a P2Y12 inhibitor...
June 2018: American Heart Journal
https://www.readbyqxmd.com/read/29898676/improved-short-and-long-term-survival-associated-with-percutaneous-coronary-intervention-in-the-elderly-patients-with-acute-coronary-syndrome
#12
Xiaojing Chen, Salim Bary Barywani, Runa Sigurjonsdottir, Michael Fu
BACKGROUND: Percutaneous coronary intervention (PCI) are increasingly used in daily clinical practice in elderly patients with acute coronary syndrome (ACS) despite limited evidence. The purpose of this study was to assess the impact of PCI on short and long term survivals in a large cohort of elderly patients with ACS from a "real world". METHODS: We enrolled 491 patients aged ≥70 years admitted to our institution with ACS from 2006 to 2012. Effect of PCI on short and long term survival was evaluated in both overall and a propensity score-matched cohort...
June 7, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29896758/use-of-the-adapted-diabetes-complications-severity-index-to-predict-acute-coronary-syndrome-ischemic-stroke-and-mortality-in-asian-patients-with-type-2-diabetes-mellitus-a-nationwide-cohort-investigation
#13
Wei-Syun Hu, Cheng-Li Lin
OBJECTIVE: We report a retrospective population study aiming at identifying and validating the adapted diabetes complications severity index (DCSI) for acute coronary syndrome (ACS), ischemic stroke and mortality in Asian people with type 2 diabetes mellitus (DM). METHODS: Utilizing the Taiwanese national dataset, we included 84450 type 2 diabetic individuals between 2000 and 2011. The area under the curve in the presentation of receiver operating characteristic (C-statistics of logistic model) and the C-statistics of Cox model were used to evaluate whether the progression of type 2 DM could be a predictor of ACS, ischemic stroke and death...
June 12, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29896264/effects-of-hyperglycaemia-and-elevated-glycosylated-haemoglobin-on-contrast-induced-nephropathy-after-coronary-angiography
#14
Yu-Han Qin, Gao-Liang Yan, Chang-Le Ma, Cheng-Chun Tang, Gen-Shan Ma
In patients undergoing percutaneous coronary intervention after acute myocardial infarction, hyperglycaemia on admission is associated with an increased risk of contrast-induced nephropathy (CIN). However, the effects of hyperglycaemia and elevated glycosylated haemoglobin (HbA1c) on CIN have remained to be fully elucidated. Therefore, a prospective cohort study was performed, comprising 258 patients who underwent coronary angiography between May 2017 and November 2017 at Zhongda Hospital affiliated with Southeast University (Nanjing, China)...
July 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29896034/comparative-review-of-oral-p2y-12-inhibitors
#15
Renee Koski, Blake Kennedy
Current practice guidelines recommend dual antiplatelet therapy comprised of aspirin and a purinergic signaling receptor Y12 (P2Y12 ) for patients following acute coronary syndrome. This article compares the efficacy, safety, and other characteristics of the three available oral P2Y12 inhibitors-clopidogrel, prasugrel, and ticagrelor.
June 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29895612/adverse-change-in-employment-status-after-acute-myocardial-infarction-analysis-from-the-translate-acs-study
#16
Haider J Warraich, Lisa A Kaltenbach, Gregg C Fonarow, Eric D Peterson, Tracy Y Wang
BACKGROUND: Inability to resume employment after acute myocardial infarction (MI) has important implications for patients. We sought to assess the prevalence of and outcomes associated with adverse change in employment after MI in a national US cohort. METHODS AND RESULTS: The TRANSLATE-ACS study (Treatment with Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome) assessed employment status at baseline and 1 year among 9319 patients with MI (mean age, 60...
June 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29895599/activated-clotting-time-to-guide-heparin-dosing-in-non-st-segment-elevation-acute-coronary-syndrome-patients-undergoing-percutaneous-coronary-intervention-and-treated-with-iib-iiia-inhibitors-impact-on-ischemic-and-bleeding-outcomes-insights-from-the-tao-trial
#17
Jean-Guillaume Dillinger, Gregory Ducrocq, Yedid Elbez, Marc Cohen, Christoph Bode, Charles Pollack, José C Nicolau, Patrick Henry, Sasko Kedev, Stephen D Wiviott, Marc S Sabatine, Shamir R Mehta, Philippe Gabriel Steg
BACKGROUND: Monitoring anticoagulation with activated clotting time (ACT) has been proposed to reduce ischemic or bleeding events. However, the value of using ACT to improve outcomes is uncertain. This study sought to determine the relationship between ACT and outcomes during percutaneous coronary intervention in patients with non-ST-segment-elevation acute coronary syndrome (NSTE-ACS) treated by unfractionated heparin with GPIs (glycoprotein IIb/IIIa inhibitors). METHODS AND RESULTS: From the randomized TAO trial (Treatment of Acute Coronary Syndromes With Otamixaban), we analyzed the value of ACT to predict ischemic and bleeding outcomes in the 3275 patients receiving unfractionated heparin plus eptifibatide...
June 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29894677/-the-quality-of-treatment-of-patients-with-atrial-fibrillation-depending-on-the-index-of-polymorbidity-preceded-hospitalization-for-acute-coronary-syndrome
#18
J A Dorofeeva, E I Tarlovskaya
The aim of this work was a retrospective assessment of the quality of treatment, depending on the severity of polymorbidity (PM) in patients with atrial fibrillation (AF) before admission to acute coronary syndrome (ACS). MATERIALS AND METHODS: Retrospectively, 105 patients were included in the analysis (54 men (51,4 %), mean age 65,94±9,34 years) who had AF before hospitalization for ACS. The index of polymorbidity (IPM) was assessed by ME Charlson et al. (1987) in the modification of H...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29894676/-evaluation-of-long-term-adverse-cardiovascular-events-risk-after-elective-percutaneous-coronary-intervention
#19
E O Vershinina, A N Repin
OBJECTIVE: The aim of our study was to analyze long-term outcomes, to identify their predictors and to develop a model for determining the risk of long-term adverse сardiovascular events after elective percutaneous coronary interventions (PCI). MATERIALS AND METHODS: A retrospective study included 151 patients 6 years after the elective PCI. Outcomes were assessed by analyzing medical records and telephone interviews. The primary composite end point of the study was a major adverse cardiovascular event (MACCE), including death from cardiovascular causes, acute coronary syndrome, acute cerebrovascular accident...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29894353/long-term-dual-antiplatelet-therapy-pharmacological-and-clinical-implications
#20
Carlo Di Mario, Alessandro Mugelli, Pasquale Perrone Filardi, Giuseppe Rosano, Francesco Rossi
: Patients experiencing an acute coronary syndrome are exposed to an increased residual risk of recurrent coronary events. Dual antiplatelet therapy (DAPT) is highly effective in preventing atherothrombotic complications in patients with previous myocardial infarction and current guidelines recommend the prescription of DAPT for at least 12 months in all patients experiencing an acute event. However, recent findings demonstrated that long-term DAPT (over 12 months) is related to a better outcome in patients at high risk, suggesting the use of a long-term DAPT to achieve a better clinical outcome...
June 11, 2018: Journal of Cardiovascular Medicine
keyword
keyword
119198
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"