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acute coronary syndrome angiography

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https://www.readbyqxmd.com/read/28623668/impact-of-pci-appropriateness-in-the-long-term-outcomes-of-consecutive-patients-treated-with-second-generation-drug-eluting-stents
#1
Ana Cristina Seixas, Amanda Sousa, Jose de Ribamar Costa, Adriana Costa Moreira, Ricardo Costa, Lucas Damiani, Cantídio Campos Neto, Galo Maldonado, Manuel Cano, J Eduardo Sousa
BACKGROUND: Appropriate use criteria (AUC) for coronary revascularization were developed to deliver high-quality care; however, the prognostic impact of these criteria remains unclear. We sought to assess the outcomes of patients treated with second-generation drug-eluting stent (DES) classified according to the updated American College of Cardiology Foundation/American Heart Association/Society for Cardiac Angiography and Intervention AUC for percutaneous coronary intervention (PCI)...
June 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28623174/sex-differences-in-the-management-and-5-year-outcome-of-young-patients-55y-with-acute-coronary-syndromes
#2
Avi Sabbag, Shlomi Matetzky, Avital Porter, Zaza Iakobishvili, Mady Moriel, Donna Zwas, Paul Fefer, Elad Asher, Roy Beigel, Shmuel Gottlieb, Ilan Goldenberg, Amit Segev
BACKGROUND: Young women are usually protected against coronary artery disease due to hormonal and risk-factor profile. Previous studies have suggested poorer outcome in women hospitalized with acute coronary syndrome as compared to men. However, when adjusted to age and other risk factors, this difference does not remain significant. We compared the risk-profile and outcome between young (≤55) women and men admitted with acute coronary syndrome. METHODS: We analyzed clinical characteristics, management strategies, and outcomes of men and women ≤55y enrolled in the biennial Acute Coronary Syndrome Israeli Surveys (ACSIS) between 2000 and 2013...
June 13, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28617303/prognostic-value-of-coronary-collaterals-in-patients-with-acute-coronary-syndromes
#3
Alparslan Kurtul, Selcuk Ozturk
BACKGROUND: The presence of good coronary collateral circulation (CCC) can protect and preserve myocardium from ischemia, increase myocardial contractility, and reduce adverse clinical events. However, its impact on mortality is still a topic of debate, particularly in acute coronary syndrome (ACS). The aim of this study was to investigate the association of CCC with cardiac risk factors and in-hospital mortality in patients hospitalized with a diagnosis of ACS. METHODS: The study population included 2286 patients with ACS who underwent coronary angiography and were found to have at least 90% significant lesion in at least one major coronary artery...
April 17, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28615234/impact-of-routine-fractional-flow-reserve-on-management-decision-and-1-year-clinical-outcome-of-patients-with-acute-coronary-syndromes-prime-ffr-insights-from-the-post-it-portuguese-study-on-the-evaluation-of-ffr-guided-treatment-of-coronary-disease-and-r3f
#4
Eric Van Belle, Sergio-Bravo Baptista, Luís Raposo, John Henderson, Gilles Rioufol, Lino Santos, Christophe Pouillot, Ruben Ramos, Thomas Cuisset, Rita Calé, Emmanuel Teiger, Elisabete Jorge, Loic Belle, Carina Machado, Didier Barreau, Marco Costa, Michel Hanssen, Eduardo Oliveira, Cyril Besnard, João Costa, Jean Dallongeville, João Pipa, Georgios Sideris, Nuno Fonseca, Christophe Bretelle, Jorge Guardado, Nicolas Lhoest, Bruno Silva, Pierre Barnay, Maria-João Sousa, Laurent Leborgne, João Carlos Silva, Flavien Vincent, Alberto Rodrigues, Luís Seca, Renato Fernandes, Patrick Dupouy
BACKGROUND: Fractional flow reserve (FFR) is not firmly established as a guide to treatment in patients with acute coronary syndromes (ACS). Primary goals were to evaluate the impact of integrating FFR on management decisions and on clinical outcome of patients with ACS undergoing coronary angiography, as compared with patients with stable coronary artery disease. METHODS AND RESULTS: R3F (French FFR Registry) and POST-IT (Portuguese Study on the Evaluation of FFR-Guided Treatment of Coronary Disease), sharing a common design, were pooled as PRIME-FFR (Insights From the POST-IT and R3F Integrated Multicenter Registries - Implementation of FFR in Routine Practice)...
June 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28614245/wellens-syndrome-in-hiv-infected-patients-two-case-reports
#5
Bowei Tan, Carlos Morales-Mangual, Dan Zhao, Abdullah Khan, Hal Chadow
BACKGROUND: Wellens syndrome is a pattern of electrocardiographic (ECG) changes in the context of unstable angina characterized with deep inverted T-waves or biphasic T-waves in the precordial leads. These specific ECG changes are highly suggestive of stenosis in the left anterior descending artery (LAD), which can result in acute myocardial infarction, left ventricular dysfunction, or death. Human immunodeficiency virus (HIV) infection is known as an independent risk factor for the cardiovascular disease...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28608183/acc-aats-aha-ase-asnc-scai-scct-sts-2017-appropriate-use-criteria-for-coronary-revascularization-in-patients-with-stable-ischemic-heart-disease-a-report-of-the-american-college-of-cardiology-appropriate-use-criteria-task-force-american-association-for-thoracic
#6
Manesh R Patel, John H Calhoon, Gregory J Dehmer, James Aaron Grantham, Thomas M Maddox, David J Maron, Peter K Smith
The American College of Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, and American Association for Thoracic Surgery, along with key specialty and subspecialty societies, have completed a 2-part revision of the appropriate use criteria (AUC) for coronary revascularization. In prior coronary revascularization AUC documents, indications for revascularization in acute coronary syndromes and stable ischemic heart disease (SIHD) were combined into 1 document. To address the expanding clinical indications for coronary revascularization, and to align the subject matter with the most current American College of Cardiology/American Heart Association guidelines, the new AUC for coronary artery revascularization were separated into 2 documents addressing SIHD and acute coronary syndromes individually...
June 12, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28606999/invasive-management-strategies-and-antithrombotic-treatments-in-patients-with-non-st-segment-elevation-acute-coronary-syndrome-in-china-findings-from-the-improving-ccc-project-care-for-cardiovascular-disease-in-china
#7
Qing Yang, Ying Wang, Jing Liu, Jun Liu, Yongchen Hao, Sidney C Smith, Yong Huo, Gregg C Fonarow, Changsheng Ma, Junbo Ge, Kathryn A Taubert, Louise Morgan, Yang Guo, Wei Wang, Yujie Zhou, Dong Zhao
BACKGROUND: Early invasive strategies and antithrombotic treatments are key treatments of non-ST-segment-elevation acute coronary syndrome (NSTE-ACS). Few studies have examined the use of these strategies in patients with NSTE-ACS in China. This study aimed to assess the applications of invasive strategies and antithrombotic treatments in patients with NSTE-ACS and compare their outcomes. METHODS AND RESULTS: A nationwide registry study, Improving CCC (Care for Cardiovascular Disease in China) ACS project, was launched in 2014 as a collaborative study of the American Heart Association and Chinese Society of Cardiology (CSC), with 142 participating hospitals reporting details of clinical management and outcomes of patients with NSTE-ACS...
June 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28605143/enhanced-serum-levels-of-matrix-gla-protein-and-bone-morphogenetic-protein-in-acute-coronary-syndrome-patients
#8
Zafer Buyukterzi, Ummugulsum Can, Sertac Alpaydin, Asuman Guzelant, Sukru Karaarslan, Mehmet Mustu, Duygu Kocyigit, Kadri Murat Gurses
BACKGROUND: Vascular calcification has been found to be associated with increased risk of cardiovascular (CV) morbidity and mortality. Various bone-associated proteins have been suggested to be related with this process. In this study, we aimed to evaluate whether serum levels of bone morphogenic protein-4 (BMP-4) and matrix Gla protein (MGP) differed in patients who were found to have normal epicardial coronary arteries or a culprit lesion in the coronary angiography leading to acute coronary syndrome (ACS)...
June 12, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28598510/relative-efficacy-and-safety-of-ticagelor-vs-clopidogrel-as-a-function-of-time-to-invasive-management-in-non-st-segment-elevation-acute-coronary-syndrome-in-the-plato-trial
#9
Charles V Pollack, Farideh Davoudi, Deborah B Diercks, Richard C Becker, Stefan K James, Soo Teik Lim, Phillip J Schulte, Jindrich Spinar, Philippe Gabriel Steg, Robert F Storey, Anders Himmelmann, Lars Wallentin, Christopher P Cannon
BACKGROUND: Guidelines suggest that "upstream" P2Y12 receptor antagonists should be considered in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS). HYPOTHESIS: Early use of ticagrelor in patients managed with an invasive strategy would be more effective than clopidogrel because of its more rapid onset of action and greater potency. METHODS: In the PLATO trial, 6792 NSTE-ACS patients were randomized to ticagrelor or clopidogrel (started prior to angiography) and underwent angiography within 72 hours of randomization...
June 9, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28590305/management-of-diabetic-patients-hospitalized-for-acute-coronary-syndromes-a-prospective-multicenter-registry
#10
Marco Ferlini, Giuseppe Musumeci, Andrea Demarchi, Niccolò Grieco, Antonio Mafrici, Stefano De Servi, Roberta Rossini, Carlo Sponzilli, Paola Bognetti, Antonino Cardile, Silvia Frattini, Alfonso Ielasi, Alessandra Russo, Claudia Vecchiato, Corrado Lettieri, Luigi O Visconti
BACKGROUND: Patients with diabetes mellitus and acute coronary syndrome (ACS) present an increased risk of adverse cardiovascular events. An Italian Consensus Document indicated 'three specific must' to obtain in this subgroup of patients: optimal oral antiplatelet therapy, early invasive approach and a tailored strategy of revascularization for unstable angina/non-ST-elevation-myocardial infarction (UA/NSTEMI); furthermore, glycemia at admission should be managed with dedicated protocols...
June 5, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28567310/absence-of-left-circumflex-artery-a-rare-congenital-disorder-of-coronary-arteries
#11
Saad Ullah, Muzammil Khan, Noman Ahmed Jang Khan, Hassan Zeb, Roshan Patel
Congenital absence of left circumflex artery is a rare occurrence and very few cases have been reported in literature. It is a benign incidental finding; however some patients present with sudden onset chest pain mimicking acute coronary syndrome often resulting in detection of this rare anatomy on coronary angiography. Coronary computed tomography angiography is a relatively new noninvasive imaging modality which can be used to confirm this suspicion and diagnose this unique morphology reliably.
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28566597/intravascular-images-of-coronary-stenosis-with-multiple-channels-in-a-patient-with-antiphospholipid-syndrome-the-optical-coherence-tomography-findings
#12
Shigenori Ito, Takahiro Hasuo
Intravascular images of coronary stenosis by antiphospholipid syndrome (APS) would be beneficial to understand the mechanism of this disease. A 59-year-old woman with APS/systemic lupus erythematosis (SLE) underwent emergent coronary angiography which revealed stenosis with micro channels in the proximal left anterior descending artery. According to optical coherence tomography (OCT), the central lumen was surrounded by a thick septum with a homogenous and high intensity. Multiple small channels existed near the vessel wall with diffuse intimal hyperplasia...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28566295/significance-of-microvascular-function-in-visual-functional-mismatch-between-invasive-coronary-angiography-and-fractional-flow-reserve
#13
Taishi Yonetsu, Tadashi Murai, Yoshihisa Kanaji, Tetsumin Lee, Junji Matsuda, Eisuke Usui, Masahiro Hoshino, Makoto Araki, Takayuki Niida, Masahiro Hada, Sadamitsu Ichijo, Rikuta Hamaya, Yoshinori Kanno, Tsunekazu Kakuta
BACKGROUND: Despite a moderate correlation between angiographical stenosis and physiological significance, the mechanism of discordance has not been fully elucidated, particularly regarding the significance of microvascular function. This study sought to clarify whether microvascular function affects visual-functional mismatch between quantitative coronary angiography (QCA) and fractional flow reserve (FFR). METHODS AND RESULTS: We assessed QCA, FFR, coronary flow reserve, and the index of microcirculatory resistance in 849 non-left-main coronary lesions with visually estimated intermediate stenoses from 532 patients...
May 31, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28561986/rationale-design-and-baseline-characteristics-of-the-clarify-registry-of-outpatients-with-stable-coronary-artery-disease
#14
Emmanuel Sorbets, Nicola Greenlaw, Roberto Ferrari, Ian Ford, Kim M Fox, Jean-Claude Tardif, Michal Tendera, Philippe Gabriel Steg
BACKGROUND: Despite major advances in prevention and treatment, coronary artery disease (CAD) remains the leading cause of death worldwide. Whereas many sources of data are available on the epidemiology of acute coronary syndromes, fewer datasets reflect the contemporary management and outcomes of stable CAD patients. HYPOTHESIS: A worldwide contemporary registry would improve our knowledge about stable CAD. The main objectives are to describe the demographics, clinical profile, contemporary management and outcomes of outpatients with stable CAD; to identify gaps between evidence and treatment; and to investigate long-term prognostic determinants...
May 31, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28559653/clinical-characteristics-of-patients-less-than-forty-years-old-with-coronary-artery-disease-in-taiwan-a-cross-sectional-study
#15
Wei-Che Tsai, Keng-Yi Wu, Gen-Min Lin, Sy-Jou Chen, Wei-Shiang Lin, Shih-Ping Yang, Shu-Meng Cheng, Chin-Sheng Lin
BACKGROUND: Coronary artery disease (CAD) rarely occurs in young adults. Our objective was to investigate the baseline characteristics and outcomes of young patients with CAD. METHODS: We retrospectively enrolled patients aged < 40 years of age who underwent coronary angiography in a tertiary hospital in Taiwan between 2002 and 2015. The baseline characteristics and in-hospital outcomes of patients with acute coronary syndrome (ACS) and occlusive CAD (stenotic lesions > 50%) were compared with those of patients without ACS and non-occlusive CAD, respectively...
May 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/28556187/lipopolysaccharide-a-possible-molecular-mediator-between-periodontitis-and-coronary-artery-disease
#16
John M Liljestrand, Susanna Paju, Kåre Buhlin, Rutger G Persson, Seppo Sarna, Markku S Nieminen, Juha Sinisalo, Päivi Mäntylä, Pirkko J Pussinen
AIM: We aimed to study how lipopolysaccharide in saliva and serum associates with each other, periodontal microbial burden, periodontitis and coronary artery disease. MATERIALS AND METHODS: The used Parogene-cohort comprised N=505 Finnish adults. Coronary diagnosis was acquired by coronary angiography and the main outcomes were: no significant coronary artery disease (n = 123), stable coronary artery disease (n = 184) and acute coronary syndrome (n = 169). Periodontitis was defined according to clinical and radiographic examinations...
May 27, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28555523/clinical-outcomes-of-patients-with-acute-coronary-syndrome-and-moderate-or-severe-chronic-anaemia-undergoing-coronary-angiography-or-intervention
#17
Lea Ohana-Sarna-Cahan, Shaul Atar
BACKGROUND: There are limited data on the impact of chronic moderate or severe anaemia on the clinical outcomes of patients with acute coronary syndrome undergoing coronary angiography or percutaneous coronary intervention. METHODS: We retrospectively compared two groups of consecutive patients with acute coronary syndrome according to their haemoglobin level on admission. The research group ( n=89) had a haemoglobin level of 10.9 g/dl or less and a control group ( n=79) of age-matched patients had a haemoglobin level greater than 10...
May 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28541597/patients-with-acute-myocardial-infarction-and-severe-target-lesion-calcifications-undergoing-percutaneous-coronary-intervention-have-poor-long-term-prognosis
#18
Wojciech Jan Zimoch, Piotr Kubler, Michał Kosowski, Brunon Tomasiewicz, Justyna Krzysztofik, Anna Langner, Ewa Anita Jankowska, Krzysztof Reczuch
BACKGROUND: To assess the influence of severe target lesion calcification (TLC) on outcomes of patients undergoing percutaneous coronary interventions (PCI) due to acute myocardial infarction (AMI). AIM: Contemporary data concerning coronary artery calcifications (CAC) are based on pooled analyses from randomized trials with short follow up. We still lack the knowledge on how CAC in target lesions affect long term prognosis of patients with AMI in everyday practice...
May 25, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28539300/-clinical-outcomes-of-intravascular-ultrasound-in-guiding-the-treatment-of-non-left-main-intermediate-coronary-lesions-for-patients-with-acute-coronary-syndrome
#19
Hong-Bin Liang, Qian Guo, Xin-Lu Zhang, Xue-Wei Liu, Yong-Zhen Tang, Wei-Yu Chen, Yu-Qing Hou, Jian-Cheng Xiu
OBJECTIVE: To evaluate the long-term clinical outcomes of intravascular ultrasound(IVUS) in guiding the treatment of non-left main intermediate coronary lesions for patients of acute coronary syndrome (ACS). METHODS: A total of 25 patients with intermediate coronary lesions(stenosis of 40%-70%) confirmed by coronary angiography were performed with IVUS. When MLA≥4 mm(2), we deferred the PCI treatment and performed optimal medical treatment (OMT). The patient were followed up for 12 month...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28534549/-patients-with-vulnerable-coronary-plaques-have-higher-serum-metalloproteinase-1-levels
#20
G Sánchez Elvira, I Coma-Canella, M Artaiz, J A Páramo, J Barba, J Calabuig
BACKGROUND: Most acute coronary syndromes are caused by the fracture of a vulnerable atherosclerotic plaque. These plaques are thin cap fibroatheromas, which can only be detected with invasive coronary imaging techniques. It is necessary to find a non-invasive biomarker of these vulnerable plaques in order to identify patients at risk without a coronary angiography. Metalloproteinase-1 is an enzyme involved in extracellular matrix metabolism which has been correlated with the rupture of atherosclerotic plaques...
April 30, 2017: Anales del Sistema Sanitario de Navarra
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