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https://www.readbyqxmd.com/read/29777125/development-of-an-algorithm-to-identify-patients-with-physician-documented-insomnia
#1
Uri Kartoun, Rahul Aggarwal, Andrew L Beam, Jennifer K Pai, Arnaub K Chatterjee, Timothy P Fitzgerald, Isaac S Kohane, Stanley Y Shaw
We developed an insomnia classification algorithm by interrogating an electronic medical records (EMR) database of 314,292 patients. The patients received care at Massachusetts General Hospital (MGH), Brigham and Women's Hospital (BWH), or both, between 1992 and 2010. Our algorithm combined structured variables (such as International Classification of Diseases 9th Revision [ICD-9] codes, prescriptions, laboratory observations) and unstructured variables (such as text mentions of sleep and psychiatric disorders in clinical narrative notes)...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776408/pre-and-intra-operative-predictors-of-postoperative-hospital-length-of-stay-in-patients-undergoing-radical-prostatectomy-for-prostate-cancer-in-china-a-retrospective-observational-study
#2
Qingmei Huang, Ping Jiang, Lina Feng, Liping Xie, Shuo Wang, Dan Xia, Baihua Shen, Baiye Jin, Li Zheng, Wei Wang
BACKGROUND: Hospital length of stay (LOS) has recently been receiving increasing attention as a marker of medical resource consumption. Identifying predictors of longer LOS can better equip doctors to counsel patients and facilitate more efficient patient flow and utilization of medical resources. The objective of this study was to identify pre- and intra-operative risk factors for postoperative hospital LOS in patients who had undergone radical prostatectomy in China. METHODS: We retrospectively analyzed data of 793 eligible patients with prostate cancer who had undergone radical prostatectomy in our institution between January 2011 and March 2016...
May 18, 2018: BMC Urology
https://www.readbyqxmd.com/read/29775981/from-auto-to-allotransplantation-immunomodulatory-protocol-for-hand-and-arm-transplantation
#3
W P Andrew Lee, Jaimie T Shores, Gerald Brandacher
AIM:  To achieve a favorable risk-benefit balance for hand transplantation, an immunomodulatory protocol was developed in the laboratory and translated to clinical application. METHODS:  Following donor bone marrow infusion into transplant recipients, hand and arm allografts have been maintained on low-dose tacrolimus monotherapy. RESULTS:  Good-to-excellent functional recovery has been achieved in patients compliant with medication and therapy, thus restoring autonomous and productive lives...
May 18, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29774423/diagnosis-and-management-of-gynecomastia-for-urologists
#4
REVIEW
Lee Baumgarten, Ali A Dabaja
PURPOSE OF REVIEW: Our aim is to review the steps of diagnosis and management of gynecomastia with a special focus on treatment of gynecomastia associated with androgen deprivation therapy for prostate cancer. RECENT FINDINGS: Recent studies investigating tamoxifen and radiation therapy for both therapy and prophylaxis of bicalutamide-induced gynecomastia are reviewed. Gynecomastia is a common clinical problem, affecting between one and two thirds of middle-aged men...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29773712/acute-kidney-injury-and-risk-of-heart-failure-and-atherosclerotic-events
#5
Alan S Go, Chi-Yuan Hsu, Jingrong Yang, Thida C Tan, Sijie Zheng, Juan D Ordonez, Kathleen D Liu
BACKGROUND AND OBJECTIVES: AKI in the hospital is common and is associated with excess mortality. We examined whether AKI is also independently associated with a higher risk of different cardiovascular events in the first year after discharge. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a retrospective analysis of a cohort between 2006 and 2013 with follow-up through 2014, within Kaiser Permanente Northern California. We identified all adults admitted to 21 hospitals who had one or more in-hospital serum creatinine test result and survived to discharge...
May 17, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29773069/high-altitude-pulmonary-hypertension
#6
Maurizio Bussotti, Giovanni Marchese
The effects of hypoxia on the human organism has been considered doubly fascinating by the scientific community: the knowledge of the discrete mechanisms allowing the acclimatization both at the genetic level or through the cell mediators production in addition to the macroscopic responses of the cardio-circulatory and ventilatory systems to a hypoxic environment has been progressively developed since the last century; moreover granting a safer stay in hypoxic conditions not only for the residents but also for the different cathegories of workers, sportsmen and tourists has been considered a worthy aim of the medical activity...
May 17, 2018: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/29772993/shoulder-lesion-in-a-69-year-old-woman
#7
Andrew J Hayden, Srinivas Kolla, Adele L Boskey, Steven Burekhovich, Chuanyong Lu, Michael Stracher, Aditya V Maheshwari
Milwaukee Shoulder Syndrome (MSS) is a painful progressive arthropathy in which hydroxyapatite crystal deposition in synovial tissue induces lysosomal release of collagenase and neutral proteases. These enzymes are destructive to periarticular tissue, including the synovium, articular cartilage, rotator cuff muscles, and the intrasynovial cortical bone. MSS predominantly occurring in women (90%) over the age of 70 years of age with a clinical history marked by recurrent joint effusions and pain, which classically worsens at night...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29772190/serum-metal-levels-in-maxillofacial-reconstructive-surgery-patients-a-pilot-study
#8
Louis G Mercuri, Michael Miloro, Anastasia K Skipor, Divya Bijukumar, Cortino Sukotjo, Mathew T Mathew
PURPOSE: The aim of this pilot study was to assay metal concentrations in the serum of patients who had undergone dental implant placement, orthognathic surgery using rigid metal fixation plates and screws, and total temporomandibular joint replacement (TMJ TJR). MATERIALS AND METHODS: Thirty patients were identified and included in this pilot study. Sixteen patients (9 men and 8 women), with an average age of 44 years (range, 19 to 79 yr), provided informed consent to participate and were divided into 3 study groups with 4 patients in each (group 1, orthognathic surgery; group 2, TMJ TJR; and group 3, dental implant placement)...
April 21, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29772111/clomiphene-citrate-and-human-chorionic-gonadotropin-are-both-effective-in-restoring-testosterone-in-hypogonadism-a-short-course-randomised-study
#9
Mohamad Habous, Simone Giona, Alaa Tealab, Mohammed Aziz, Ben Williamson, Mohammed Nassar, Zeyad Abdelrahman, Abdallah Remeah, Mohamed Abdelkader, Saleh Binsaleh, Gordon Muir
OBJECTIVES: To compare serum testosterone response and symptom improvement in hypogonadal men in response to treatment by one of three options: clomiphene citrate(CC), human chorionic gonadotropin (hCG), or combination of both therapy. PATIENTS AND METHODS: 282 hypogonadal adult, willing to preserve their fertility, were randomised in three arms treated respectively with: 50 mg of (CC) (n=95), 5000IU of hCG injections twice a week(n=94) or combination of both therapy(n=94)...
May 17, 2018: BJU International
https://www.readbyqxmd.com/read/29771000/molecular-testing-in-holoprosencephaly
#10
Paul Kruszka, Ariel F Martinez, Maximilian Muenke
Holoprosencephaly (HPE) is a structural brain anomaly characterized by failure of the forebrain to separate during early embryogenesis. Both genetic and environmental etiologies of HPE have been discovered over the last three decades. Traditionally, the genetic workup for HPE has been a karyotype, chromosomal microarray, and/or Sanger sequencing of select genes. The recent increased availability of next-generation sequencing has changed the molecular diagnostic landscape for HPE, associating new genes with this disorder such as FGFR1...
May 17, 2018: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/29770700/quality-use-of-the-pathology-data-in-home-medicines-reviews-a-retrospective-evaluation
#11
Vera H Buss, Alison Shield, Sam Kosari, Mark Naunton
BACKGROUND: Laboratory tests can be important tools for the assessment of pharmacotherapy. Nonetheless, there are no previous studies that have explicitly focused on the role of pathology data in Home Medicines Reviews (HMR), an Australian medication review program. OBJECTIVE: Evaluate pharmacists' recommendations regarding laboratory testing in the medication review process. METHODS: This retrospective review of HMRs assessed the prevalence of the pathology data provided by general practitioners...
May 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29770667/-clinical-characteristics-of-16-newly-discovered-advanced-schistosomiasis-patients-in-dongpo-district-meishan-city-sichuan-province
#12
Zhou Zhi, Xu Jia, Zhang Yi
OBJECTIVE: To understand the clinical characteristics of newly discovered advanced schistosomiasis patients in Dongpo District, Meishan City, Sichuan Province, so as to provide the reference for enhancing the clinicians' awareness for diagnosis and treatment of this disease and improving the therapeutic effect. METHODS: The data of medical records and schedule of case survey of 16 newly discovered advanced schistosomiasis patients in Dongpo District, Meishan City, Sichuan Province were collected and analyzed...
April 17, 2018: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29770358/association-of-central-obesity-with-sex-hormonebinding-globulin-a-cross-sectional-study-of-1166-chinese-men
#13
Fangwei Liu, Xubo Shen, Ruifeng Wang, Na Yu, Yongjun Shi, Shimin Xiong, Chengliang Xiong, Yuanzhong Zhou
Background Both sex hormone-binding globulin and central obesity have been found to be associated with metabolic and cardiovascular diseases. However, the direct relation between sex hormone-binding globulin and central obesity has not been demonstrated. Methodology We performed a cross-sectional study of 1166 male participants from Zunyi, Guizhou, western China, in 2013. Each participant completed a questionnaire and had a brief clinical exam with a fasting blood sample taken. All blood samples underwent standard laboratory testing for sex hormone-binding globulin...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29769504/dipstick-method-versus-spot-urinary-protein-creatinine-ratio-for-evaluation-of-massive-proteinuria-in-childhood-nephrotic-syndrome
#14
M N Sultana, B Majumder, M J Rahman, A M Moniruzzaman, A M Suja, M E Ali, Z H Sarker, S N Nabi, M A Mostakim
Measurement of massive proteinuria is vital for diagnosis of childhood Nephrotic syndrome. Quantification of 24 hours urinary protein is the gold standard test. Dipstick method of urinary protein measurement gives instant result for massive proteinuria. Spot urinary protein creatinine ratio measurement is variable. This was a hospital based prospective cross sectional study done at Department of Paediatric Nephrology, Rangpur Medical College Hospital from January 2014 to December 2015 to evaluate accuracy of dipstick method versus spot urinary protein-creatinine ratio in estimation of massive proteinuria in childhood nephrotic syndrome...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769487/length-of-vermiform-appendix-in-bangladeshi-people-of-different-age-and-sex
#15
S A Sumi, M Khalil, S Mannan, S Chowdhury, M K Khan, U K Paul, U K Zaman, S F Karim, A Rahman, M M Rahman, A Kabir, S Farjan, M T Alam, E Z Epsi, N S Nitu, N J Khan, L Jabeen, S Tabriz
A cross sectional descriptive study was performed on 70 postmortem vermiform appendix (male 34 and female 36) to find out the length of vermiform appendix of Bangladeshi people in different age and sex. The specimens were collected from autopsy laboratory of the Department of Forensic Medicine, Mymensingh Medical College, Mymensingh, Bangladesh from October 2016 to March 2017 by purposive sampling technique. The collected samples were divided into four age groups. They were Group A (upto 20 years), Group B (21 to 40 years), Group C (41 to 60 years) and Group D (above 60 years)...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769160/cross-border-outbreak-of-extensively-drug-resistant-tuberculosis-linked-to-a-university-in-romania
#16
O Popovici, Ph Monk, D Chemtob, D Chiotan, P J Freidlin, R Groenheit, M Haanperä, D Homorodean, M Mansjö, E Robinson, E Rorman, G Smith, H Soini, M J Van Der Werf
Extensively drug-resistant (XDR) tuberculosis (TB) poses a threat to public health due to its complicated, expensive and often unsuccessful treatment. A cluster of three XDR TB cases was detected among foreign medical students of a Romanian university. The contact investigations included tuberculin skin testing or interferon gamma release assay, chest X-ray, sputum smear microscopy, culture, drug susceptibility testing, genotyping and whole-genome sequencing (WGS), and were addressed to students, personnel of the university, family members or other close contacts of the cases...
May 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29769074/delay-in-reviewing-test-results-prolongs-hospital-length-of-stay-a-retrospective-cohort-study
#17
Mei-Sing Ong, Farah Magrabi, Enrico Coiera
BACKGROUND: Failure in the timely follow-up of test results has been widely documented, contributing to delayed medical care. Yet, the impact of delay in reviewing test results on hospital length of stay (LOS) has not been studied. We examine the relationship between laboratory tests review time and hospital LOS. METHODS: A retrospective cohort study of inpatients admitted to a metropolitan teaching hospital in Sydney, Australia, between 2011 and 2012 (n = 5804)...
May 16, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29768371/complex-regional-pain-syndrome-type-ii-after-cervical-transforaminal-epidural-injection-a-case-report
#18
Gi-Young Park, Dong Rak Kwon, Dae Gil Kwon
RATIONALE: We report a case of a 61-year-old patient who developed complex regional pain syndrome (CRPS) type II after a cervical transforaminal epidural steroid injection (CTESI). PATIENT CONCERNS: The patient developed sudden-onset severe pain and swelling of his upper right limb after a cervical transforaminal epidural injection. DIAGNOSES: On physical examination, the patient's symptoms and signs corresponded to the Budapest criteria for CRPS...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29768316/evaluation-of-compliance-with-a-weight-based-nurse-driven-heparin-nomogram-in-a-tertiary-academic-medical-center
#19
James W Schurr, Craig A Stevens, Anne Bane, Sarah E Culbreth, Amy Leigh Miller, Jean M Connors, Katelyn W Sylvester
BACKGROUND: Recently, our institution adopted a weight-based nurse-driven heparin titration protocol that relies on nurses ordering laboratories, adjusting doses, and initiating boluses. Numerous institutions have implemented similar protocols with reported success. METHODS: A single-center retrospective analysis was conducted at the Brigham and Women's Hospital in Boston, Massachusetts that included all patients who were initiated on the weight-based nurse-driven heparin nomogram during a 30-day period...
June 2018: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/29768314/medication-administration-delays-in-non-st-elevation-myocardial-infarction-analysis-of-1002-patients-admitted-to-an-academic-medical-center
#20
LeAnn N Denlinger, Ellen C Keeley
Our goal was to assess adherence to American College of Cardiology/American Heart Association guideline-based medical therapy in patients admitted with type I non-ST elevation myocardial infarction (NSTEMI) and to determine factors associated with medication administration delay. We performed a retrospective analysis using data from the Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry. Baseline patient demographics, 12-lead electrocardiogram (ECG) findings, laboratory values, medications administered and the time they were administered, and in-hospital clinical outcomes were collected...
June 2018: Critical Pathways in Cardiology
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