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scleritis alendronic acid

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https://www.readbyqxmd.com/read/23766431/pro-inflammatory-and-anti-angiogenic-effects-of-bisphosphonates-on-human-cultured-retinal-pigment-epithelial-cells
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Chris Or, Jing Cui, Joanne Matsubara, Farzin Forooghian
AIM: Bisphosphonates have been shown to induce ocular inflammatory diseases such as uveitis and scleritis, while being protective against angiogenic diseases like neovascular age-related macular degeneration (AMD). Therefore, we studied the effects of bisphosphonates on primary culture of human fetal retinal pigment epithelium (hRPE), a cell type known to secrete both inflammatory and angiogenic factors. Alendronate and etidronate were selected for this experiment as they are members of the two structurally different classes of bisphosphonates...
August 2013: British Journal of Ophthalmology
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