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Water Fat MRI

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https://www.readbyqxmd.com/read/27898602/novel-high-spatiotemporal-resolution-versus-standard-of-care-dynamic-contrast-enhanced-breast-mri-comparison-of-image-quality
#1
Courtney K Morrison, Leah C Henze Bancroft, Wendy B DeMartini, James H Holmes, Kang Wang, Ryan J Bosca, Frank R Korosec, Roberta M Strigel
OBJECTIVE: Currently, dynamic contrast-enhanced (DCE) breast magnetic resonance imaging (MRI) prioritizes spatial resolution over temporal resolution given the limitations of acquisition techniques. The purpose of our intrapatient study was to assess the ability of a novel high spatial and high temporal resolution DCE breast MRI method to maintain image quality compared with the clinical standard-of-care (SOC) MRI. MATERIALS AND METHODS: Thirty patients, each demonstrating a focal area of enhancement (29 benign, 1 cancer) on their SOC MRI, consented to undergo a research DCE breast MRI on a second date...
November 28, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/27890779/fast-triple-spin-echo-dixon-ftsed-sequence-for-water-and-fat-imaging
#2
R Korinek, K Bartusek, Z Starcuk
A number of 'Dixon' techniques based on fast spin echo (FSE) sequence have been proposed and successfully used in many branches of medicine. Some require only one scan, but most of them need multiple scans and long scan times. This article describes a new fast triple-spin-echo Dixon (FTSED) technique suitable for ultra-high field MRI, in which three specific time shifts are introduced in the echo train; thus, three images with defined water-fat phase-differences (0, π, 2π) are encoded in the phase of the acquired images without extreme restrictions upon the echo duration...
November 24, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27859853/monoexponential-biexponential-and-stretched-exponential-diffusion-weighted-imaging-models-quantitative-biomarkers-for-differentiating-renal-clear-cell-carcinoma-and-minimal-fat-angiomyolipoma
#3
Haojie Li, Lili Liang, Anqin Li, Yao Hu, Daoyu Hu, Zhen Li, Ihab R Kamel
PURPOSE: To determine the utility of various diffusion parameters obtained from monoexponential, biexponential, and stretched exponential diffusion-weighted imaging (DWI) models in differentiating between minimal fat angiomyolipoma (MFAML) and clear cell renal cell carcinoma (ccRCC). MATERIALS AND METHODS: One hundred thirty-one patients with pathologically confirmed MFAML (n = 27) or ccRCC (n = 104) underwent multi-b value DWI (0∼1700 s/mm(2) ) imaging at 3...
November 10, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27826082/spectrally-presaturated-modulation-spm-an-efficient-fat-suppression-technique-for-steam-based-cardiac-imaging-sequences
#4
Ahmed S Fahmy, El-Sayed H Ibrahim, Nael F Osman
Stimulated-echo acquisition mode (STEAM) is a key pulse sequences in MRI in general, and in cardiac imaging in particular. Fat suppression is an important feature in cardiac imaging to improve visualization and eliminate off-resonance and chemical-shift artifacts. Nevertheless, fat suppression comes at the expense of reduced temporal resolution and signal-to-noise ratio (SNR). The purpose of this study is to develop an efficient fat suppression method (Spectrally-Presaturated Modulation) for STEAM-based sequences to enable imaging with high temporal-resolution, high SNR, and no increase in scan time...
November 4, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27822655/accelerating-multi-echo-water-fat-mri-with-a-joint-locally-low-rank-and-spatial-sparsity-promoting-reconstruction
#5
Felix Lugauer, Dominik Nickel, Jens Wetzl, Berthold Kiefer, Joachim Hornegger, Andreas Maier
OBJECTIVES: Our aim was to demonstrate the benefits of using locally low-rank (LLR) regularization for the compressed sensing reconstruction of highly-accelerated quantitative water-fat MRI, and to validate fat fraction (FF) and [Formula: see text] relaxation against reference parallel imaging in the abdomen. MATERIALS AND METHODS: Reconstructions using spatial sparsity regularization (SSR) were compared to reconstructions with LLR and the combination of both (LLR+SSR) for up to seven fold accelerated 3-D bipolar multi-echo GRE imaging...
November 7, 2016: Magma
https://www.readbyqxmd.com/read/27775180/robust-water-fat-separated-dual-echo-mri-by-phase-sensitive-reconstruction
#6
Thobias Romu, Nils Dahlström, Olof Dahlqvist Leinhard, Magnus Borga
PURPOSE: The purpose of this work was to develop and evaluate a robust water-fat separation method for T1-weighted symmetric two-point Dixon data. THEORY AND METHODS: A method for water-fat separation by phase unwrapping of the opposite-phase images by phase-sensitive reconstruction (PSR) is introduced. PSR consists of three steps; (1), identification of clusters of tissue voxels; (2), unwrapping of the phase in each cluster by solving Poisson's equation; and (3), finding the correct sign of each unwrapped opposite-phase cluster, so that the water-fat images are assigned the correct identities...
October 24, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27725802/preclinical-in-vivo-imaging-for-fat-tissue-identification-quantification-and-functional-characterization
#7
Pasquina Marzola, Federico Boschi, Francesco Moneta, Andrea Sbarbati, Carlo Zancanaro
Localization, differentiation, and quantitative assessment of fat tissues have always collected the interest of researchers. Nowadays, these topics are even more relevant as obesity (the excess of fat tissue) is considered a real pathology requiring in some cases pharmacological and surgical approaches. Several weight loss medications, acting either on the metabolism or on the central nervous system, are currently under preclinical or clinical investigation. Animal models of obesity have been developed and are widely used in pharmaceutical research...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27692023/effects-of-initiating-moderate-wine-intake-on-abdominal-adipose-tissue-in-adults-with-type-2-diabetes-a-2-year-randomized-controlled-trial
#8
Rachel Golan, Ilan Shelef, Elad Shemesh, Yaakov Henkin, Dan Schwarzfuchs, Yftach Gepner, Ilana Harman-Boehm, Shula Witkow, Michael Friger, Yoash Chassidim, Idit F Liberty, Benjamin Sarusi, Dana Serfaty, Nitzan Bril, Michal Rein, Noa Cohen, Sivan Ben-Avraham, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Meir J Stampfer, Assaf Rudich, Iris Shai
OBJECTIVE: To generate evidence-based conclusions about the effect of wine consumption on weight gain and abdominal fat accumulation and distribution in patients with type 2 diabetes. DESIGN: In the 2-year randomized controlled CASCADE (CArdiovaSCulAr Diabetes & Ethanol) trial, patients following a Mediterranean diet were randomly assigned to drink 150 ml of mineral water, white wine or red wine with dinner for 2 years. Visceral adiposity and abdominal fat distribution were measured in a subgroup of sixty-five participants, using abdominal MRI...
October 3, 2016: Public Health Nutrition
https://www.readbyqxmd.com/read/27649492/upper-limb-evaluation-in-duchenne-muscular-dystrophy-fat-water-quantification-by-mri-muscle-force-and-function-define-endpoints-for-clinical-trials
#9
Valeria Ricotti, Matthew R B Evans, Christopher D J Sinclair, Jordan W Butler, Deborah A Ridout, Jean-Yves Hogrel, Ahmed Emira, Jasper M Morrow, Mary M Reilly, Michael G Hanna, Robert L Janiczek, Paul M Matthews, Tarek A Yousry, Francesco Muntoni, John S Thornton
OBJECTIVE: A number of promising experimental therapies for Duchenne muscular dystrophy (DMD) are emerging. Clinical trials currently rely on invasive biopsies or motivation-dependent functional tests to assess outcome. Quantitative muscle magnetic resonance imaging (MRI) could offer a valuable alternative and permit inclusion of non-ambulant DMD subjects. The aims of our study were to explore the responsiveness of upper-limb MRI muscle-fat measurement as a non-invasive objective endpoint for clinical trials in non-ambulant DMD, and to investigate the relationship of these MRI measures to those of muscle force and function...
2016: PloS One
https://www.readbyqxmd.com/read/27648658/to-assess-differential-features-of-marrow-adiposity-between-postmenopausal-women-with-osteoarthritis-and-osteoporosis-using-water-fat-mri
#10
Guanwu Li, Zheng Xu, Jingzheng Fan, Wei Yuan, Lina Zhang, Lingmi Hou, Dongmei Wu, Shixin Chang, Horea Calimente, Jiani Hu
OBJECTIVE: To assess the differential features of marrow adiposity between osteoarthritis (OA) and osteoporosis (OP) in postmenopausal women using water/fat MRI. METHODS: This cross-sectional study included 97 postmenopausal women (OA [n = 25], OA + osteopenia [n = 27], OA + OP [n = 23], and OP groups [n = 22]). Water/fat MRI, dual-energy x-ray absorptiometry and biochemical analysis were performed to assess vertebral marrow fat fraction, bone mineral density, and bone biomarkers, respectively...
September 19, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27622137/abnormal-white-matter-microstructure-and-increased-extracellular-free-water-in-the-cingulum-bundle-associated-with-delusions-in-chronic-schizophrenia
#11
Lena K L Oestreich, Ofer Pasternak, Martha E Shenton, Marek Kubicki, Xue Gong, Simon McCarthy-Jones, Thomas J Whitford
BACKGROUND: There is growing evidence to suggest that delusions associated with schizophrenia arise from altered structural brain connectivity. The present study investigated whether structural changes in three major fasciculi that interconnect the limbic system - the cingulum bundle, uncinate fasciculus and fornix - are associated with delusions in chronic schizophrenia patients. METHODS: Free-water corrected Diffusion Tensor Imaging was used to investigate the association between delusions and both microstructural changes within these three fasciculi and extracellular changes in the surrounding free-water...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27605407/emulsion-stability-modulates-gastric-secretion-and-its-mixing-with-emulsified-fat-in-healthy-adults-in-a-randomized-magnetic-resonance-imaging-study
#12
Dian Liu, Helen L Parker, Jelena Curcic, Sebastian Kozerke, Andreas Steingoetter
BACKGROUND: Oil-in-water emulsions have recently become of interest to nutritional sciences because of their ability to influence gastrointestinal digestive processes and ultimately benefit human health. MRI offers the potential to noninvasively characterize the interaction between emulsified lipids and gastric secretion within the stomach. OBJECTIVES: We determined noninvasively how emulsion stability modulates volumes of fat and secretion, layering of fat, and the mixing of emulsified fat with secretion within the stomach...
October 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27590177/an-investigation-of-fat-infiltration-of-the-multifidus-muscle-in-patients-with-severe-neck-symptoms-associated-with-chronic-whiplash-associated-disorder
#13
Anette Karlsson, Olof Dahlqvist Leinhard, Ulrika Åslund, Janne West, Thobias Romu, Örjan Smedby, Peter Zsigmond, Anneli Peolsson
Study Design Cross-sectional study. Background Findings of fat infiltration in cervical spine multifidus, as a sign of degenerative morphometric changes due to whiplash injury, need to be verified. Objectives To develop a method using water/fat magnetic resonance imaging (MRI) to investigate fat infiltration and cross-sectional area of multifidus muscle in individuals with whiplash-associated disorders (WADs) compared to healthy controls. Methods Fat infiltration and cross-sectional area in the multifidus muscles spanning the C4 to C7 segmental levels were investigated by manual segmentation using water/fat-separated MRI in 31 participants with WAD and 31 controls, matched for age and sex...
October 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27579856/chemical-shift-magnetization-transfer-magnetic-resonance-imaging
#14
Weiguo Li, Xifu Wang, Frank H Miller, Andrew C Larson
PURPOSE: The purpose of this work was to develop a chemical shift magnetization transfer (CSMT) magnetic resonance imaging (MRI) method to provide accurate magnetization transfer ratio (MTR) measurements in the presence of fat. METHODS: Numerical simulations were performed to compare MTR measurements at different echo times (TEs) for voxels with varying fat/water content. The CSMT approach was developed using water fraction estimates to correct for the impact of fat signal upon observed MTR measurements...
August 31, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27569370/on-the-r2-%C3%A2-relaxometry-in-complex-multi-peak-multi-echo-chemical-shift-based-water-fat-quantification-applications-to-the-neuromuscular-diseases
#15
Giulio Siracusano, Aurelio La Corte, Carmelo Milazzo, Giuseppe Pio Anastasi, Giovanni Finocchio, Michele Gaeta
PURPOSE: Investigation of the feasibility of the R2(⁎) mapping techniques by using latest theoretical models corrected for confounding factors and optimized for signal to noise ratio. THEORY AND METHODS: The improvement of the performance of state of the art magnetic resonance imaging (MRI) relaxometry algorithms is challenging because of a non-negligible bias and still unresolved numerical instabilities. Here, R2(⁎) mapping reconstructions, including complex fitting with multi-spectral fat-correction by using single-decay and double-decay formulation, are deeply studied in order to investigate and identify optimal configuration parameters and minimize the occurrence of numerical artifacts...
August 26, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27549160/comparing-the-mri-based-goutallier-classification-to-an-experimental-quantitative-mr-spectroscopic-fat-measurement-of-the-supraspinatus-muscle
#16
Fabian Gilbert, Dirk Böhm, Lars Eden, Jonas Schmalzl, Rainer H Meffert, Herbert Köstler, Andreas M Weng, Dirk Ziegler
BACKGROUND: The Goutallier Classification is a semi quantitative classification system to determine the amount of fatty degeneration in rotator cuff muscles. Although initially proposed for axial computer tomography scans it is currently applied to magnet-resonance-imaging-scans. The role for its clinical use is controversial, as the reliability of the classification has been shown to be inconsistent. The purpose of this study was to compare the semi quantitative MRI-based Goutallier Classification applied by 5 different raters to experimental MR spectroscopic quantitative fat measurement in order to determine the correlation between this classification system and the true extent of fatty degeneration shown by spectroscopy...
2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27503308/diffusion-weighted-echo-planar-mr-imaging-of-the-neck-at-3%C3%A2-t-using-integrated-shimming-comparison-of-mr-sequence-techniques-for-reducing-artifacts-caused-by-magnetic-field-inhomogeneities
#17
Sergios Gatidis, Hansjörg Graf, Jakob Weiß, Alto Stemmer, Berthold Kiefer, Konstantin Nikolaou, Mike Notohamiprodjo, Petros Martirosian
OBJECTIVE: Our objective was to compare available techniques reducing artifacts in echo planar imaging (EPI)-based diffusion-weighed magnetic resonance imaging MRI (DWI) of the neck at 3 Tesla caused by B0-field inhomogeneities. MATERIALS AND METHODS: A cylindrical fat-water phantom was equipped with a Maxwell coil allowing for additional linear B0-field variations in z-direction. The effect of increasing strength of this superimposed gradient on image quality was observed using a standard single-shot EPI-based DWI sequence (sEPI), a zoomed single-shot EPI sequence (zEPI), a readout-segmented EPI sequence (rsEPI), and an sEPI sequence with integrated dynamic shimming (intEPI) on a 3-Tesla system...
August 8, 2016: Magma
https://www.readbyqxmd.com/read/27501897/automatic-segmentation-of-abdominal-organs-and-adipose-tissue-compartments-in-water-fat-mri-application-to-weight-loss-in-obesity
#18
Jun Shen, Thomas Baum, Christian Cordes, Beate Ott, Thomas Skurk, Hendrik Kooijman, Ernst J Rummeny, Hans Hauner, Bjoern H Menze, Dimitrios C Karampinos
PURPOSE: To develop a fully automatic algorithm for abdominal organs and adipose tissue compartments segmentation and to assess organ and adipose tissue volume changes in longitudinal water-fat magnetic resonance imaging (MRI) data. MATERIALS AND METHODS: Axial two-point Dixon images were acquired in 20 obese women (age range 24-65, BMI 34.9±3.8kg/m(2)) before and after a four-week calorie restriction. Abdominal organs, subcutaneous adipose tissue (SAT) compartments (abdominal, anterior, posterior), SAT regions along the feet-head direction and regional visceral adipose tissue (VAT) were assessed by a fully automatic algorithm using morphological operations and a multi-atlas-based segmentation method...
September 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27430444/magnetic-resonance-imaging-of-skeletal-muscle-disease
#19
Bruce M Damon, Ke Li, Nathan D Bryant
Neuromuscular diseases often exhibit a temporally varying, spatially heterogeneous, and multifaceted pathology. The goals of this chapter are to describe and evaluate the use of quantitative magnetic resonance imaging (MRI) methods to characterize muscle pathology. The following criteria are used for this evaluation: objective measurement of continuously distributed variables; clear and well-understood relationship to the pathology of interest; sensitivity to improvement or worsening of clinical status; and the measurement properties of accuracy and precision...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27427989/recent-developments-in-muscle-imaging-of-neuromuscular-disorders
#20
Dirk Fischer, Ulrike Bonati, Mike P Wattjes
PURPOSE OF REVIEW: In this update, we describe recent findings on imaging techniques used for the analysis and quantification of affected muscles, advances in pattern recognition, and quantitative muscle imaging in clinical studies. RECENT FINDINGS: Whole-body muscle MRI and meta-analytical approaches, so-called (hierarchical) heat maps of affected muscles are promising advances compared with commonly applied lower leg pattern recognition approaches. Muscle fat fraction assessments measuring chemical shift differences and T2-relaxation times of separated fat and water components in skeletal muscle are currently the most reliable quantitative muscle imaging techniques...
October 2016: Current Opinion in Neurology
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