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Water Fat MRI

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https://www.readbyqxmd.com/read/29774594/in-vivo-characterization-of-3d-skull-and-brain-motion-during-dynamic-head-vibration-using-magnetic-resonance-elastography
#1
Ziying Yin, Yi Sui, Joshua D Trzasko, Phillip J Rossman, Armando Manduca, Richard L Ehman, John Huston
PURPOSE: To introduce newly developed MR elastography (MRE)-based dual-saturation imaging and dual-sensitivity motion encoding schemes to directly measure in vivo skull-brain motion, and to study the skull-brain coupling in volunteers with these approaches. METHODS: Six volunteers were scanned with a high-performance compact 3T-MRI scanner. The skull-brain MRE images were obtained with a dual-saturation imaging where the skull and brain motion were acquired with fat- and water-suppression scans, respectively...
May 17, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29772956/lumbar-muscle-structure-predicts-operational-postures-in-active-duty-marines
#2
David B Berry, Bahar Shahidi, Ana E Rodríguez-Soto, Jan M Hughes-Austin, Karen R Kelly, Samuel R Ward
Study Design Cross-sectional. Background The relationship between lumbar spine posture and muscle structure is not well understood. Objectives Investigate the predictive capacity of muscle structure on lumbar spine posture in active duty Marines. Methods Fouty-three Marines were scanned using an upright magnetic resonance imaging (MRI) scanner while standing unloaded and standing, sitting, and prone on elbows with body armor. Cobb, horizontal, and sacral angles were measured. Marines were then scanned unloaded in supine using a supine MRI scanner...
May 17, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29772058/technical-note-interleaved-bipolar-acquisition-and-low-rank-reconstruction-for-water-fat-separation-in-mri
#3
JaeJin Cho, HyunWook Park
PURPOSE: To acquire interleaved bipolar data and reconstruct the full data using low-rank property for water fat separation. METHODS: Bipolar acquisition suffers from issues related to gradient switching, the opposite gradient polarities, and other system imperfections, which prevent accurate water-fat separation. In this study, an interleaved bipolar acquisition scheme and a low-rank reconstruction method were proposed to reduce issues from the bipolar gradients while achieving a short imaging time...
May 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/29771283/adolescents-at-high-risk-of-obesity-show-greater-striatal-response-to-increased-sugar-content-in-milkshakes
#4
Grace E Shearrer, Eric Stice, Kyle S Burger
Background: Children of overweight or obese parents are at a high risk of developing obesity. Objective: This study sought to examine the underlying neural factors related to parental obesity risk and the relative impact of sugar and fat when consuming a palatable food, as well as the impact of obesity risk status on brain response to appetizing food images. Design: With the use of functional MRI, the responses of 108 healthy-weight adolescents [mean ± SD body mass index (kg/m2): 20...
May 16, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29770772/fse-t2-weighted-two-point-dixon-technique-for-fat-suppression-in-the-lumbar-spine-comparison-with-spair-technique
#5
Sangmin Lee, Dae Seob Choi, Hwa Seon Shin, Hye Jin Baek, Ho Cheol Choi, Sung Eun Park
PURPOSE: Fat suppression magnetic resonance imaging (MRI) technique has been used to improve the diagnostic confidence in lumbar spine diseases. We aimed to compare T2-weighted water-fat separation technique (T2 Dixon) with spectral attenuated inversion recovery (SPAIR) image for fat suppression. METHODS: Lumbar spine MRI examinations were performed in 79 patients by using a 3.0 T machine. We compared T2 Dixon water-only image and SPAIR image for the evaluation of fat suppression quality and lesion conspicuity...
May 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29770503/a-novel-phase-unwrapping-method-by-using-phase-jump-detection-and-local-surface-fitting-application-to-dixon-water-fat-mri
#6
Junying Cheng, Jijing Guan, Yingjie Mei, Lin Xu, Xiaoyun Liu, Qianjin Feng, Wufan Chen, Yanqiu Feng
PURPOSE: This study aims to develop an accurate and robust phase-unwrapping method that works effectively under severe noise, rapid-varying phase, and disconnected regions for water-fat Dixon MRI. METHODS: The proposed method first segments the phase map into blocks by automatically detecting phase jumps, and then clusters the pixels near phase jumps into residual pixels. Thereafter, the proposed method sequentially performs intrablock, interblock, and residual-pixel unwrapping using the local surface fitting approach...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29742918/can-unenhanced-mri-of-the-breast-replace-contrast-enhanced-mri-in-assessing-response-to-neoadjuvant-chemotherapy
#7
Beatrice Cavallo Marincola, Marianna Telesca, Fulvio Zaccagna, Frank Riemer, Michele Anzidei, Carlo Catalano, Federica Pediconi
Background The goals of neoadjuvant chemotherapy (NAC) are to reduce tumor volume and to offer a prognostic indicator in assessing treatment response. Contrast-enhanced magnetic resonance imaging (CE-MRI) is an established method for evaluating response to NAC in patients with breast cancer. Purpose To validate the role of unenhanced MRI (ue-MRI) compared to CE-MRI for assessing response to NAC in women with breast cancer. Material and Methods Seventy-one patients with ongoing NAC for breast cancer underwent MRI before, during, and at the end of NAC...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29736849/diagnostic-accuracy-of-3t-magnetic-resonance-imaging-in-the-preoperative-localisation-of-parathyroid-adenomas-comparison-with-ultrasound-and-99mtc-sestamibi-scans
#8
Renato Argirò, Daniele Diacinti, Beatrice Sacconi, Angelo Iannarelli, Davide Diacinti, Cristiana Cipriani, Daniela Pisani, Elisabetta Romagnoli, Marco Biffoni, Cira Di Gioia, Jessica Pepe, Mario Bezzi, Claudio Letizia, Salvatore Minisola, Carlo Catalano
OBJECTIVES: To evaluate the diagnostic performance of 3TMRI in comparison with ultrasound (US) and 99mTc-sestamibi scan for presurgical localisation of parathyroid adenomas (PTAs) in patients with primary hyperparathyroidism (PHPT). METHODS: Fifty-seven patients affected by PHPT were prospectively enrolled and underwent US, 99mTc-sestamibi and 3TMRI. T2-weighted and post-contrast T1-weighted Iterative decomposition of water and fat with Echo Asymmetry and Least squares estimation (IDEAL) sequences were acquired...
May 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29729148/brown-adipose-tissue-in-young-adults-who-were-born-preterm-or-small-for-gestational-age
#9
Anna Kistner, Henric Rydén, Björn Anderstam, Ann Hellström, Mikael Skorpil
BACKGROUND: Brown adipose tissue (BAT) is present and functions to dissipate energy as heat in young adults and can be assessed using magnetic resonance imaging (MRI) to estimate the voxel fat fraction, i.e. proton density fat fraction (PDFF). It is hypothesized that subjects born preterm or small for gestational age (SGA) may exhibit disrupted BAT formation coupled to metabolic factors. Our purpose was to assess the presence of BAT in young adults born extremely preterm or SGA in comparison with controls...
May 5, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29705265/acetyl-coa-carboxylase-inhibitor-gs-0976-for-12-weeks-reduces-hepatic-de-novo-lipogenesis-and-steatosis-in-patients-with-nonalcoholic-steatohepatitis
#10
Eric J Lawitz, Angie Coste, Fred Poordad, Naim Alkhouri, Nicole Loo, Bryan J McColgan, Jacqueline M Tarrant, Tuan Nguyen, Ling Han, Chuhan Chung, Adrian S Ray, John G McHutchison, G Mani Subramanian, Robert P Myers, Michael S Middleton, Claude Sirlin, Rohit Loomba, Edna Nyangau, Mark Fitch, Kelvin Li, Marc Hellerstein
BACKGROUND & AIMS: Increased de novo lipogenesis (DNL) contributes to the pathogenesis of nonalcoholic steatohepatitis (NASH). Acetyl-CoA carboxylase catalyzes the rate-limiting step in DNL. We evaluated the safety and efficacy of GS 0976, a small molecule inhibitor of acetyl-CoA carboxylase, in patients with NASH. METHODS: In an open-label prospective study, patients with NASH (n=10) received GS-0976 20 mg orally once daily for 12 weeks. NASH was diagnosed based on a proton density fat fraction estimated by magnetic resonance imaging (MRI-PDFF) >10% and liver stiffness by magnetic resonance elastography (MRE) >2...
April 26, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29704560/identification-of-an-optimal-threshold-for-detecting-human-brown-adipose-tissue-using-receiver-operating-characteristic-analysis-of-ideal-mri-fat-fraction-maps
#11
Terence A Jones, Sarah C Wayte, Narendra L Reddy, Oludolapo Adesanya, George K Dimitriadis, Thomas M Barber, Charles E Hutchinson
PURPOSE: Lower fat fraction (FF) in brown adipose tissue (BAT) than white adipose tissue (WAT) has been exploited using Dixon-based Magnetic Resonance Imaging (MRI) to differentiate these tissues in rodents, human infants and adults. We aimed to determine whether an optimal FF threshold could be determined to differentiate between BAT and WAT in adult humans in vivo. METHODS: Sixteen volunteers were recruited (9 females, 7 males; 44.2 ± 19.2 years) based on BAT uptake on 18 F-FDG PET/CT...
April 25, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29685536/a-subjective-and-objective-comparison-of-tissue-contrast-and-imaging-artifacts-present-in-routine-spin-echoes-and-in-iterative-decomposition-of-asymmetric-spin-echoes-for-soft-tissue-neck-mri
#12
Subhendra N Sarkar, David B Hackney, Robert L Greenman, Behroze A Vachha, Emelia A Johnson, Sue Nagle, Gul Moonis
OBJECTIVE: FSE sequences play key roles in neck MRI despite the susceptibility issues in neck region. Iterative decomposition of asymmetric echoes (IDEAL, GE) is a promising method that separates fat and water images resulting in high SNR and improved fat suppression. We tested how neck tissue contrasts, image artifacts and fat separation as opposed to fat suppression in terms of image quality compare between routine and IDEAL FSE. METHODS: IDEAL based and routine T1 and T2 -weighted FSE sequences were applied for neck MRI at 1...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29682313/systematic-assessment-of-the-growth-plates-of-the-wrist-in-young-gymnasts-development-and-validation-of-the-amsterdam-mri-assessment-of-the-physis-amphys-protocol
#13
Laura S Kox, Rik B J Kraan, Kees F van Dijke, Robert Hemke, Sjoerd Jens, Milko C de Jonge, Edwin H G Oei, Frank F Smithuis, Maaike P Terra, Mario Maas
Objectives: To develop and validate a protocol for MRI assessment of the distal radial and ulnar periphyseal area in gymnasts and non-gymnasts. Methods: Twenty-four gymnasts with wrist pain, 18 asymptomatic gymnasts and 24 non-gymnastic controls (33 girls) underwent MRI of the wrist on a 3T scanner. Sequences included coronal proton density-weighted images with and without fat saturation, and three-dimensional water-selective cartilage scan and T2 Dixon series. Skeletal age was determined using hand radiographs...
2018: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29670577/anatomical-variation-of-age-related-changes-in-vertebral-bone-marrow-composition-using-chemical-shift-encoding-based-water-fat-magnetic-resonance-imaging
#14
Thomas Baum, Alexander Rohrmeier, Jan Syväri, Maximilian N Diefenbach, Daniela Franz, Michael Dieckmeyer, Andreas Scharr, Hans Hauner, Stefan Ruschke, Jan S Kirschke, Dimitrios C Karampinos
Assessment of vertebral bone marrow composition has been proposed as imaging biomarker for osteoporosis, hematopoietic, and metabolic disorders. We investigated the anatomical variation of age-related changes of vertebral proton density fat fraction (PDFF) using chemical shift encoding-based water-fat magnetic resonance imaging (MRI). 156 healthy subjects were recruited (age range 20-29 years: 12/30 males/females; 30-39: 15/9; 40-49: 4/14; 50-59: 9/27; 60-69: 5/19; 70-79: 4/8). An eight-echo 3D spoiled gradient-echo sequence at 3T MRI was used for chemical shift-encoding based water-fat separation at the lumbar spine...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29605590/measurement-of-fat-fraction-in-the-human-thymus-by-localized-nmr-and-three-point-dixon-mri-techniques
#15
Kenneth W Fishbein, Sokratis K Makrogiannis, Vanessa A Lukas, Marilyn Okine, Ramona Ramachandran, Luigi Ferrucci, Josephine M Egan, Chee W Chia, Richard G Spencer
PURPOSE: To develop a protocol to non-invasively measure and map fat fraction, fat/(fat+water), as a function of age in the adult thymus for future studies monitoring the effects of interventions aimed at promoting thymic rejuvenation and preservation of immunity in older adults. MATERIALS AND METHODS: Three-dimensional spoiled gradient echo 3T MRI with 3-point Dixon fat-water separation was performed at full inspiration for thymus conspicuity in 36 volunteers 19 to 56 years old...
March 29, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29602018/low-dose-caffeine-as-a-salivary-tracer-for-the-determination-of-gastric-water-emptying-in-fed-and-fasted-state-a-mri-validation-study
#16
Maximilian Sager, Philipp Jedamzik, Simon Merdivan, Michael Grimm, Felix Schneider, Marie-Luise Kromrey, Mahmoud Hasan, Stefan Oswald, Jens Kühn, Mirko Koziolek, Werner Weitschies
Improving our knowledge about human gastrointestinal physiology and its impact on oral drug delivery is crucial for the development of new therapies and effective drug delivery systems. The aim of this study was to develop an in vivo tool to determine gastric emptying of water by administration of a caffeine as a tracer substance followed by subsequent saliva caffeine analysis. For this purpose, 35mg of caffeine were given to six healthy volunteers after a 10h overnight together with 240mL of tap water either on a fasted stomach or 30min after the high-caloric, high-fat breakfast recommended for bioavailability/bioequivalence (BA/BE) studies...
March 27, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29594090/assessing-exposures-to-magnetic-resonance-imaging-s-complex-mixture-of-magnetic-fields-for-in-vivo-in-vitro-and-epidemiologic-studies-of-health-effects-for-staff-and-patients
#17
Jennifer Frankel, Jonna Wilén, Kjell Hansson Mild
A complex mixture of electromagnetic fields is used in magnetic resonance imaging (MRI): static, low-frequency, and radio frequency magnetic fields. Commonly, the static magnetic field ranges from one to three Tesla. The low-frequency field can reach several millitesla and with a time derivative of the order of some Tesla per second. The radiofrequency (RF) field has a magnitude in the microtesla range giving rise to specific absorption rate values of a few Watts per kilogram. Very little attention has been paid to the case where there is a combined exposure to several different fields at the same time...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29566449/quantitative-susceptibility-mapping-qsm-minimizes-interference-from-cellular-pathology-in-r2-estimation-of-liver-iron-concentration
#18
Jianqi Li, Huimin Lin, Tian Liu, Zhuwei Zhang, Martin R Prince, Kelly Gillen, Xu Yan, Qi Song, Ting Hua, Xiance Zhao, Miao Zhang, Yu Zhao, Gaiying Li, Guangyu Tang, Guang Yang, Gary M Brittenham, Yi Wang
BACKGROUND: A challenge for R2 and R2* methods in measuring liver iron concentration (LIC) is that fibrosis, fat, and other hepatic cellular pathology contribute to R2 and R2* and interfere with LIC estimation. PURPOSE: To examine the interfering effects of fibrosis, fat, and other lesions on R2* LIC estimation and to use quantitative susceptibility mapping (QSM) to reduce these distortions. STUDY TYPE: Prospective. PHANTOMS, SUBJECTS: Water phantoms with various concentrations of gadolinium (Gd), collagen (Cl, modeling fibrosis), and fat; nine healthy controls with no known hepatic disease, nine patients with known or suspected hepatic iron overload, and nine patients with focal liver lesions...
March 22, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29545214/hybrid-quantitative-mri-using-chemical-shift-displacement-and-recovery-based-simultaneous-water-and-lipid-imaging-a-preliminary-study
#19
Naoki Ohno, Tosiaki Miyati, Shuto Suzuki, Hirohito Kan, Toshitaka Aoki, Yoshitaka Nakamura, Yuki Hiramatsu, Satoshi Kobayashi, Toshifumi Gabata
PURPOSE: To suppress olefinic signals and enable simultaneous and quantitative estimation of multiple functional parameters associated with water and lipid, we investigated a modified method using chemical shift displacement and recovery-based separation of lipid tissue (SPLIT) involving acquisitions with different inversion times (TIs), echo times (TEs), and b-values. MATERIALS AND METHODS: Single-shot diffusion echo-planar imaging (SSD-EPI) with multiple b-values (0-3000 s/mm2 ) was performed without fat suppression to separate water and lipid images using the chemical shift displacement of lipid signals in the phase-encoding direction...
March 12, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29496516/magnetic-resonance-imaging-and-spectroscopy-evidence-of-efficacy-for-adrenal-and-gonadal-hormone-replacement-therapy-in-anorexia-nervosa
#20
Sridhar Vajapeyam, Kirsten Ecklund, Robert V Mulkern, Henry A Feldman, Jennifer M O'Donnell, Amy D DiVasta, Clifford J Rosen, Catherine M Gordon
PURPOSE: Dehydroepiandrosterone (DHEA)+estrogen/progestin therapy for adolescent girls with anorexia nervosa (AN) has the potential to arrest bone loss. The primary aim of this study was to test the effects of DHEA+estrogen/progestin therapy in adolescent girls with AN on bone marrow in the distal femur using magnetic resonance imaging (MRI) and spectroscopy. METHODS: Seventy adolescent girls with AN were enrolled in a double blind, randomized, placebo-controlled trial at two urban hospital-based programs...
May 2018: Bone
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