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Susceptibility Weighted Imaging

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https://www.readbyqxmd.com/read/27893493/improving-detection-of-iron-deposition-in-cirrhotic-liver-using-susceptibility-weighted-imaging-with-emphasis-on-histopathological-correlation
#1
Ruo-Kun Li, Meng-Su Zeng, Fu-Hua Yan, Jin-Wei Qiang, Suzanne L Palmer, Frank Chen, Sheng-Xiang Rao, Ling-Li Chen, Yong-Ming Dai
OBJECTIVE: The aim of this study was to investigate the value of susceptibility-weighted imaging (SWI) for detection and quantification of iron deposition in cirrhotic liver. METHODS: Fifty-five cirrhotic patients underwent hepatic magnetic resonance imaging examination including SWI and multiecho T2*-weighted imaging (T2*WI). Detection of iron deposition and number of siderotic nodules were compared between SWI and T2*WI. Correlation among SWI phase value, T2* value, and hepatic iron concentration were determined...
November 23, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27889089/susceptible-vessel-sign-identification-of-arterial-occlusion-and-clinical-implications-in-acute-ischaemic-stroke
#2
S Payabvash, J C Benson, S Taleb, J B Rykken, B Hoffman, A M McKinney, M C Oswood
AIM: To determine the accuracy of the susceptible vessel sign (SVS) in the detection of arterial occlusion and its clinical implication in acute ischaemic stroke. MATERIALS AND METHODS: Consecutive ischaemic stroke patients who underwent magnetic resonance imaging (MRI) with susceptibility-weighted imaging (SWI) within 24 hours of symptom onset or time last-seen-well were included. Two independent neuroradiologists reviewed the SWI for evidence of the SVS. Admission stroke severity was determined by the National Institute of Health Stroke Scale (NIHSS) scores, and poor clinical outcome was defined by a 3-months modified Rankin scale (mRS) score >2...
November 23, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27889022/advanced-mr-imaging-in-pediatric-brain-tumors-clinical-applications
#3
REVIEW
Maarten Lequin, Jeroen Hendrikse
Advanced MR imaging techniques, such as spectroscopy, perfusion, diffusion, and functional imaging, have improved the diagnosis of brain tumors in children and also play an important role in defining surgical as well as therapeutic responses in these patients. In addition to the anatomic or structural information gained with conventional MR imaging sequences, advanced MR imaging techniques also provide physiologic information about tumor morphology, metabolism, and hemodynamics. This article reviews the physiology, techniques, and clinical applications of diffusion-weighted and diffusion tensor imaging, MR spectroscopy, perfusion MR imaging, susceptibility-weighted imaging, and functional MR imaging in the setting of neuro-oncology...
February 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/27882200/calcification-in-globus-pallidus-and-putamen-of-multiple-sclerosis-patients-versus-healthy-subjects-using-quantitative-susceptibility-mapping
#4
Muhammad Arshad Javid, M Afzal Khan, Naima Amin, Azeem Nabi
BACKGROUND: Calcification has been well reported in basal ganglia and it grows rapidly in globus pallidus (GP) followed by putamen (PUT) and caudate nucleus because of their high metabolic rate and displays high susceptibility effects. Therefore, the current study focused on magnetic susceptibility effect of calcium content in normal and diseased tissue due to metabolic changes. OBJECTIVES: To evaluate calcium content in GP and PUT structures of multiple sclerosis (MS) patients versus healthy subjects using quantitative susceptibility mapping...
October 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27879446/quantification-of-serial-cerebral-blood-flow-in-acute-stroke-using-arterial-spin-labeling
#5
George W J Harston, Thomas W Okell, Fintan Sheerin, Ursula Schulz, Phil Mathieson, Ian Reckless, Kunal Shah, Gary A Ford, Michael A Chappell, Peter Jezzard, James Kennedy
BACKGROUND AND PURPOSE: Perfusion-weighted imaging is used to select patients with acute ischemic stroke for intervention, but knowledge of cerebral perfusion can also inform the understanding of ischemic injury. Arterial spin labeling allows repeated measurement of absolute cerebral blood flow (CBF) without the need for exogenous contrast. The aim of this study was to explore the relationship between dynamic CBF and tissue outcome in the month after stroke onset. METHODS: Patients with nonlacunar ischemic stroke underwent ≤5 repeated magnetic resonance imaging scans at presentation, 2 hours, 1 day, 1 week, and 1 month...
November 22, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27875002/superparamagnetic-nanoparticle-enhanced-mri-of-alzheimer-s-disease-plaques-and-activated-microglia-in-3x-transgenic-mouse-brains-contrast-optimization
#6
Marissa A Tafoya, Saaussan Madi, Laurel O Sillerud
PURPOSE: To optimize magnetic resonance imaging (MRI) of antibody-conjugated superparamagnetic nanoparticles for detecting amyloid-β plaques and activated microglia in a 3X transgenic mouse model of Alzheimer's disease. MATERIALS AND METHODS: Ten 3X Tg mice were fed either chow or chow containing 100 ppm resveratrol. Four brains, selected from animals injected with either anti-amyloid targeted superparamagnetic iron oxide nanoparticles, or anti-Iba-1-conjugated FePt-nanoparticles, were excised, fixed with formalin, and placed in Fomblin for ex vivo MRI (11...
November 22, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27871078/cerebral-microhemorrhages-and-meningeal-siderosis-in-infective-endocarditis
#7
Ajay Malhotra, Joseph Schindler, Brian Mac Grory, Stacy Y Chu, Teddy S Youn, Charles Matouk, David M Greer, Matthew Schrag
OBJECTIVE: Patients with infective endocarditis (IE) frequently experience cerebral insults, and neurological involvement in IE has been reported to herald a worse prognosis. In this manuscript, we describe a distinctive pattern of findings on susceptibility-weighted imaging (SWI) sequences in subjects with IE. METHODS: Patients with IE who underwent SWI MRI at an academic hospital from 2009 to 2014 were retrospectively analyzed. The pattern of findings was compared to SWI findings in groups of subjects with cerebral amyloid angiopathy (CAA) or severe hypertension...
November 22, 2016: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/27870820/in-reply-can-we-rely-on-susceptibility-weighted-imaging-swi-for-subthalamic-nucleus-identification-in-deep-brain-stimulation-surgery
#8
Maarten Bot, Pepijn van den Munckhof
No abstract text is available yet for this article.
December 2016: Neurosurgery
https://www.readbyqxmd.com/read/27862452/effects-of-biological-tissue-structural-anisotropy-and-anisotropy-of-magnetic-susceptibility-on-the-gradient-echo-mri-signal-phase-theoretical-background
#9
Dmitriy A Yablonskiy, Alexander L Sukstanskii
Quantitative susceptibility mapping is a potentially powerful technique for mapping tissue magnetic susceptibility from gradient recalled echo (GRE) MRI signal phase. In this review, we present up-to-date theoretical developments in analyzing the relationships between GRE signal phase and the underlying tissue microstructure and magnetic susceptibility at the cellular level. Two important phenomena contributing to the GRE signal phase are at the focus of this review - tissue structural anisotropy (e.g. cylindrical axonal bundles in white matter) and magnetic susceptibility anisotropy...
November 11, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27859983/imaging-of-nigrosome-1-in-substantia-nigra-at-3t-using-multiecho-susceptibility-map-weighted-imaging-smwi
#10
Yoonho Nam, Sung-Min Gho, Dong-Hyun Kim, Eung Yeop Kim, Jongho Lee
PURPOSE: To enhance the visibility of nigrosome 1 in substantia nigra, which has recently been suggested as an imaging biomarker for Parkinson's disease (PD) at 3T magnetic resonance imaging (MRI). MATERIALS AND METHODS: The substantia nigra structure was visualized at 3T MRI using multiecho susceptibility map-weighted imaging (SMWI) in 15 healthy volunteers and 6 patients with Parkinson's disease (PD). The visibility of nigrosome 1 was further enhanced by acquiring data in an oblique-coronal imaging plane at a high spatial resolution (0...
November 11, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27858213/prognostic-relevance-of-gemistocytic-grade-ii-astrocytoma-gemistocytic-component-and-mr-imaging-features-compared-to-non-gemistocytic-grade-ii-astrocytoma
#11
Young Jin Heo, Ji Eun Park, Ho Sung Kim, Ji Ye Lee, Soo Jeong Nam, Seung Chai Jung, Choong Gon Choi, Sang Joon Kim
OBJECTIVES: To determine if gemistocytic grade II astrocytoma (GemA) and its MR imaging characteristics are associated with a shorter time-to-progression (TTP) compared with non-gemistocytic grade II astrocytoma (non-GemA). MATERIALS AND METHODS: We enrolled 78 patients who were followed up more than 5 years (29 pathologically proven GemA and 49 non-GemA) during a 10-year period. Contrast-enhanced T1-weighted, diffusion-weighted imaging (DWI), dynamic susceptibility contrast (DSC), and MR spectroscopy (MRS) and clinical data were retrospectively reviewed...
November 17, 2016: European Radiology
https://www.readbyqxmd.com/read/27857923/a-case-of-traumatic-unilateral-internuclear-ophthalmoplegia-clinical-significance-of-susceptibility-weighted-imaging
#12
Shin-Heon Lee, Taek-Kyun Nam, Yong-Sook Park, Jeong-Taik Kwon
A 43-year-old man was admitted for head trauma after falling backward. The patient complained of diplopia. Unilateral internuclear ophthalmoplegia (INO) was diagnosed during the neurologic examination. Initially, no specific finding was shown on T2-weighted, T1-weighted, and fluid attenuated inversion recovery brain magnetic resonance image (MRI) or brain computed tomography (CT). However, susceptibility-weighted imaging (SWI) definitively demonstrated a tiny hemorrhage at the midline of the pontomesencephalic junction...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27851995/key-clinical-benefits-of-neuroimaging-at-7t
#13
Siegfried Trattnig, Elisabeth Springer, Wolfgang Bogner, Gilbert Hangel, Bernhard Strasser, Barbara Dymerska, Pedro Lima Cardoso, Simon Daniel Robinson
The growing interest in ultra-high field MRI, with more than 35.000 MR examinations already performed at 7T, is related to improved clinical results with regard to morphological as well as functional and metabolic capabilities. Since the signal-to-noise ratio increases with the field strength of the MR scanner, the most evident application at 7T is to gain higher spatial resolution in the brain compared to 3T. Of specific clinical interest for neuro applications is the cerebral cortex at 7T, for the detection of changes in cortical structure, like the visualization of cortical microinfarcts and cortical plaques in Multiple Sclerosis...
November 13, 2016: NeuroImage
https://www.readbyqxmd.com/read/27836650/t2-based-mr-imaging-of-hyperglycemia-induced-hemichorea-hemiballism
#14
Fang Yu, Andrew Steven, Lee Birnbaum, Wilson Altmeyer
INTRODUCTION: Hyperglycemia can induce hemichorea-hemiballism, especially in elderly type II diabetics. CT and MRI findings include hyperdensity and T1-shortening in the contralateral lentiform nucleus, respectively. This study explores the associated imaging findings on T2*-based sequences. METHODS: Six patients with clinically documented hyperglycemia-induced hemichorea-hemiballism who had undergone MR imaging with a T2*-based sequence (T2* gradient echo or susceptibility-weighted imaging) were included in this retrospective case series...
November 8, 2016: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/27834534/vestibular-balance-microvascular-and-white-matter-neuroimaging-characteristics-of-blast-injuries-and-mild-traumatic-brain-injury-four-case-reports
#15
Ramtilak Gattu, Faith W Akin, Anthony T Cacace, Courtney D Hall, Owen D Murnane, E Mark Haacke
BACKGROUND: Case reports are presented on four Veterans, aged 29-46 years, who complained of chronic dizziness and/or postural instability following blast exposures. Two of the four individuals were diagnosed with mild traumatic brain injury and three of the four were exposed to multiple blasts. Comprehensive vestibular, balance, gait, audiometry and neuroimaging procedures were used to characterize their injuries. CASE REPORT: Vestibular assessment included videonystagmography, rotary chair and cervical and ocular vestibular evoked myogenic potentials...
2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27823971/combined-use-of-susceptibility-weighted-magnetic-resonance-imaging-sequences-and-dynamic-susceptibility-contrast-perfusion-weighted-imaging-to-improve-the-accuracy-of-the-differential-diagnosis-of-recurrence-and-radionecrosis-in-high-grade-glioma-patients
#16
Tae-Hyung Kim, Tae Jin Yun, Chul-Kee Park, Tae Min Kim, Ji-Hoon Kim, Chul-Ho Sohn, Jae Kyung Won, Sung-Hye Park, Il Han Kim, Seung Hong Choi
Purpose was to assess predictive power for overall survival (OS) and diagnostic performance of combination of susceptibility-weighted MRI sequences (SWMRI) and dynamic susceptibility contrast (DSC) perfusion-weighted imaging (PWI) for differentiation of recurrence and radionecrosis in high-grade glioma (HGG). We enrolled 51 patients who underwent radiation therapy or gamma knife surgeryfollowed by resection for HGG and who developed new measurable enhancement more than six months after complete response. The lesions were confirmed as recurrence (n = 32) or radionecrosis (n = 19)...
November 3, 2016: Oncotarget
https://www.readbyqxmd.com/read/27822669/asl-and-susceptibility-weighted-imaging-contribution-to-the-management-of-acute-ischaemic-stroke
#17
REVIEW
Sébastien Verclytte, Olivier Fisch, Lucie Colas, Olivier Vanaerde, Manuel Toledano, Jean-François Budzik
: Magnetic resonance imaging (MRI) plays a central role in the early diagnosis of cerebral vascular events. Today, MRI is used not only for the detection of acute ischaemic lesions, but also to fine tune the diagnosis and improve patient selection for early therapeutic decision-making. In this perspective, new tools such as arterial spin labelling (ASL) and susceptibility-weighted imaging (SWI) sequences have been developed. These MRI sequences enable noninvasive assessment of brain damage, providing important diagnostic and prognostic information: evaluation of cerebral parenchymal perfusion; detection and aetiological assessment of thrombi; ruling out differential diagnoses...
November 7, 2016: Insights Into Imaging
https://www.readbyqxmd.com/read/27816879/all-that-bleeds-is-not-black-susceptibility-weighted-imaging-of-intracranial-hemorrhage-and-the-effect-of-t1-signal
#18
Michael B Salmela, Shri H Krishna, Douglas J Martin, Sara Khanipour Roshan, Alexander M McKinney, Huseyin G Tore, Brian Knaeble, Jeffrey B Rykken, Zuzan Cayci, Bharathi D Jagadeesan
PURPOSE: To determine if intracranial hemorrhages (ICH) are always hypointense on Susceptibility weighted imaging (SWI) and to determine the effect of T1-signal intensity on the appearance of ICH in SWI series. METHODS: SWI and T1-signal intensities of ICH were retrospectively studied in a series of patients. SWI signal intensities were statistically correlated with T1-signal intensities. RESULTS: In a series of 57 MRI scans from 40 patients, ICH was hypointense in 19, mixed-intensity in 21, and hyperintense in 17...
October 17, 2016: Clinical Imaging
https://www.readbyqxmd.com/read/27809383/ultra-high-field-rf-coil-development-for-evaluating-upper-extremity-imaging-applications
#19
Shailesh B Raval, Tiejun Zhao, Narayanan Krishnamurthy, Tales Santini, Cynthia Britton, Vijay S Gorantla, Tamer S Ibrahim
The purpose of this study is to develop and evaluate a custom-designed 7  T MRI coil and explore its use for upper extremity applications. An RF system composed of a transverse electromagnetic transmit coil and an eight-channel receive-only array was developed for 7  T upper extremity applications. The RF system was characterized and evaluated using scattering parameters and B1(+) mapping. Finite difference time domain simulations were performed to evaluate the B1(+) field distribution and specific absorption rate for the forearm region of the upper extremity...
November 3, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27806979/developmental-differences-in-the-brain-response-to-unhealthy-food-cues-an-fmri-study-of-children-and-adults
#20
Floor van Meer, Laura N van der Laan, Lisette Charbonnier, Max A Viergever, Roger Ah Adan, Paul Am Smeets
BACKGROUND: Food cues are omnipresent and may trigger overconsumption. In the past 2 decades, the prevalence of childhood obesity has increased dramatically. Because children's brains are still developing, especially in areas important for inhibition, children may be more susceptible than adults to tempting food cues. OBJECTIVE: We examined potential developmental differences in children's and adults' responses to food cues to determine how these responses relate to weight status...
November 2, 2016: American Journal of Clinical Nutrition
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