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ovarian mass adolescent

Akihiro Takeda, Kazuko Watanabe, Shotaro Hayashi, Sanae Imoto, Hiromi Nakamura
BACKGROUND: Gynandroblastoma is an extremely rare ovarian sex cord tumor with malignant potential. CASE: An 18-year-old adolescent experienced intermittent vaginal bleeding. A year later, right adnexal mass with a heterogeneous imaging appearance was identified. Laparoendoscopic single-site ovarian tumorectomy was performed. A histopathological examination showed gynandroblastoma composed of juvenile granulosa and Sertoli-Leydig cells. Since the tumor was upstaged to stage Ic due to cyst rupture during surgery, three cycles of adjuvant chemotherapy with carboplatin and paclitaxel were added...
October 14, 2016: Journal of Pediatric and Adolescent Gynecology
Patcharapa Thaweekul, Yuthadej Thaweekul, Karicha Mairiang
A 13-year-old, obese girl presented with acute abdominal pain with abdominal distension for a year. The physical examination revealed marked abdominal distension with a large well-circumscribed mass sized 13×20 cm. Her body mass index (BMI) was 37.8 kg/m2. An abdominal CT scan revealed a huge multiloculated cystic mass and a left adnexal mass. She had an abnormal fasting plasma glucose and low HDL-C. Laparotomy, right salpingooophorectomy, left cystectomy, lymph node biopsies and partial omentectomy were performed...
December 2016: Asia Pacific Journal of Clinical Nutrition
Zhi-Hui Tan, Yi Zhang, Yu Zhang
OBJECTIVE: To study the clinical features of gynecological diseases in hospitalized children. METHODS: A retrospective analysis was performed for the clinical data of 147 children with gynecological diseases who were hospitalized and treated in the department of gynecology. RESULTS: Among the 147 children, ovarian tumors were most common (53 cases, 36.1%), followed by reproductive tract dysplasia or malformation (29 cases, 19.7%), adolescent dysfunctional uterine bleeding (18 cases, 12...
September 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Lauren M Bergeron, Katherine C Bishop, Holly R Hoefgen, Margaret S Abraham, Nhial T Tutlam, Diane F Merritt, Jeffrey F Peipert
STUDY OBJECTIVE: The purpose of this study was to compare ovarian conservation rates and surgical approach in benign adnexal surgeries performed by surgeons versus gynecologists at a tertiary care institution. DESIGN: A retrospective cohort review. SETTING: Children's and Adult tertiary care university-based hospital. PARTICIPANTS: Patients ≤21 years of age undergoing surgery for an adnexal mass from January 2003 through December 2013...
September 14, 2016: Journal of Pediatric and Adolescent Gynecology
Ahmad Abu Sulb, Marwa Abu El Haija, Akila Muthukumar
Pelvic tumors in adolescent females are very uncommon. While the most common presentation is pelvic discomfort, we report the case of a 14-year-old female presenting with menorrhagia which is an unusual initial complaint for a large pelvic tumor. Adolescent females who present with heavy menstrual bleeding initially undergo assessment to rule out a bleeding disorder. In this case, careful history and physical examination helped in making a quick diagnosis and management. Ultrasound of abdomen showed a huge cystic mass due to serous cystadenoma of the ovary...
2016: SAGE Open Med Case Rep
Ayke J Hermans, Kirsten B Kluivers, Laura M Janssen, Albert G Siebers, Marc H W A Wijnen, Johan Bulten, Leon F A G Massuger, Sjors F P J Coppus
OBJECTIVE: To provide an accurate incidence of adnexal masses in children and young women which can significantly improve the performance of current risk prediction models. METHODS: We used the PALGA database, a nationwide network and registry of histopathology and cytopathology, as the primary source of our study. Reports on ovarian histology of girls, years 1991-2014, and women aged 21-39, years 2011-2013, were included. Reports were labeled using the WHO-classification and classified as benign, borderline malignant, or malignant...
October 2016: Gynecologic Oncology
Onur Erol, Mesut Parlak, Hamit Yaşar Ellidağ, Ayşe Eda Parlak, Aysel Uysal Derbent, Esin Eren, Necat Yılmaz
OBJECTIVE: Free radical-mediated oxidative stress has been implicated in the etiopathogenesis of Hashimoto's thyroiditis (HT), which is the most common thyroid disorder in adolescents. HT requires lifelong thyroid surveillance, particularly in women of childbearing age to avoid adverse effects on reproductive function. The aims of this study were to investigate serum concentrations of anti-Müllerian hormone (AMH), a marker of ovarian reserve, in euthyroid adolescent girls with newly diagnosed HT and explore the relationships between AMH levels and biomarkers of antioxidant status...
August 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
S Basaranoglu, E Agacayak, S Y Tune, M S Icen, A Turgut, N Peker, M S Evsen, T Gul
OBJECTIVE: The purpose of this study was to present data on clinical and operational management and postoperative outcomes of pregnancies complicated by adnexal torsion (AT). MATERIALS AND METHODS: Twenty-four pregnant women who presented to the present clinic between January 2007 to December 2013 and were intraoperatively diagnosed with AT were included in this study. Demographic data such as age and data on obstetric history, gestational week, current trimester, previous gynecologic and non-gynecologic operations, type of surgery that was performed, average size, location and number of adnexal masses, surgical techniques that were employed, postoperative complications, and pathology results were investigated and noted...
2016: Clinical and Experimental Obstetrics & Gynecology
Parsa Salehi, Nichole Tyson
BACKGROUND: While adnexal masses and ovarian torsion are common causes of acute pain in the adolescent female, fibroids are an uncommon etiology and little is reported in the literature. Due to the rarity of adolescent leiomyomas, the best surgical management is still unknown. CASE: This is the first case report of a laparoscopic myomectomy in the adolescent population. The removed fibroid is one of the largest documented cases of uterine leiomyoma in adolescents...
June 1, 2016: Journal of Pediatric and Adolescent Gynecology
Caroline Friedman, Tamatha Fenster
BACKGROUND: Malignant ovarian germ cell tumors are rare entities, although they account for a large proportion of ovarian masses in young women. These tumors have traditionally been removed via laparotomy, because of their large size and solid nature. The use of laparoscopy for treatment of adnexal masses in adolescents has been heavily debated and poorly studied to date. CASE: A 16-year-old female patient presented with abdominal pain and an 11-cm adnexal mass on ultrasound...
June 1, 2016: Journal of Pediatric and Adolescent Gynecology
Kimberly A Bertrand, Heather J Baer, E John Orav, Catherine Klifa, Ajay Kumar, Nola M Hylton, Erin S LeBlanc, Linda G Snetselaar, Linda Van Horn, Joanne F Dorgan
BACKGROUND: Emerging evidence suggests positive associations between serum anti-Müllerian hormone (AMH), a marker of ovarian function, and breast cancer risk. Body size at young ages may influence AMH levels, but few studies have examined this. Also, no studies have examined the relation of AMH levels with breast density, a strong predictor of breast cancer risk. METHODS: We examined associations of early life body fatness, AMH concentrations, and breast density among 172 women in the Dietary Intervention Study in Children (DISC)...
July 2016: Cancer Epidemiology, Biomarkers & Prevention
T Baert, N Storme, E Van Nieuwenhuysen, A Uyttebroeck, N Van Damme, I Vergote, A Coosemans
Ovarian cancer is rare in childhood. This explains why there are only scattered reports on it in the literature and why there is a lack of specific pediatric treatment. This paper gives an overview of the Belgian data from 2004 to 2013 and reviews the literature. To index ovarian masses and malignancies in children better in the future, worldwide data collection should be improved and reproducible definitions of 'childhood', 'malignancy' and 'ovarian mass' need to be adopted.
June 2016: Maturitas
A J Hermans, K B Kluivers, A G Siebers, M H W A Wijnen, J Bulten, L F A G Massuger, S F P J Coppus
STUDY QUESTION: Is ovarian cytology a reliable predictor for a malignant ovarian mass? SUMMARY ANSWER: Cytology of an ovarian mass in children and adolescents cannot be used to exclude malignancy. WHAT IS KNOWN ALREADY: It is hard to predict malignancy in case of an ovarian mass in a child or adolescent. The most common reason to perform fine needle aspiration cytology (FNAC) is to exclude malignancy. Ovarian cytology has shown varying results in adults, but test performance in a younger population is unknown...
June 2016: Human Reproduction
F Bonilla-Musoles, C Cadete, F Raga, F Bonilla, N G Osborne, O Caballero
OBJECTIVE: To demonstrate that the use of 3D/4D HDLive increases the image quality in the diagnosis of benign cystic ovarian teratomas. MATERIALS AND METHODS: 3D/HDLive ultrasound (US) was used in 31 cases of suspected ovarian cystic teratoma using vaginal 2D US. The following pathognomonic images of mature cystic teratomas were considered for diagnosis: 1) a cystic, unilocular lesion with a densely echogenic tubercle (Rokitansky nodule); 2) a diffuse or partially echogenic mass usually demonstrating sound attenuation; 3) fluid-fluid/fat-fluid levels; 4) dermoid mesh with hyperechogenic calcifications indicating the presence of bone, teeth, or other ectodermally-derived structure; 5) multiple mobile spherical structures (fat globules)...
2016: Clinical and Experimental Obstetrics & Gynecology
Antonio Simone Laganà, Vincenza Sofo, Francesca Maria Salmeri, Vittorio Italo Palmara, Onofrio Triolo, Milan Milosav Terzić, Tito Silvio Patrelli, Adolf Lukanovic, Eda Vrtcnik Bokal, Giuseppe Santoro
Among the different causes of gynecological acute pelvic pain, ovarian torsion represents a surgical emergency. It is a rare case in the pediatric/adolescent aged group that must be included in the differential diagnosis of any girl with abdominal pain or pelvic/abdominal mass. Current recommendations suggest that laparoscopic detorsion should be performed in order to preserve the integrity of the ovaries and fertility, although oophoropexy may be considered in case of severe necrosis. Nevertheless, maintaining the circulation of the ovary after detorsion deteriorates the tissue injury and leads to a pathologic process called ischaemia/reperfusion (I/R) injury, which is characterized by oxidative stress...
January 2016: International Journal of Fertility & Sterility
Song Li, Zhenzhen Liu, Chengyong Dong, Fei Long, Qinlong Liu, Deguang Sun, Zhenming Gao, Liming Wang
Growing teratoma syndrome (GTS) is a rare clinical entity first described by Logothetis et al in 1982. Although it is unusual for GTS to be located in the ovary, this report is of a case of an adolescent girl who underwent a complete surgical resection of the mass. Histopathology confirmed only an immature teratoma had originated from the ovary and so she received adjuvant chemotherapy with blemycin, etopside, and cisplatin over 4 cycles. Results from an abdominal enhanced CT (computed tomography) 9 years later revealed a giant mass had compressed adjacent tissues and organs...
February 2016: Medicine (Baltimore)
Celine Rey-Bellet Gasser, Mario Gehri, Jean-Marc Joseph, Jean-Yves Pauchard
OBJECTIVES: This study aimed to identify, through systematic literature review, the most reliable clinical, biological, and radiological signs of ovarian torsion in the pediatric population and to compare their diagnostic value. METHODS: This is a systematic review of the literature, searching MEDLINE, EMBASE, and Cochrane Databases for articles published between January 1990 and January 2014. RESULTS: From the 946 references initially identified, 14 retrospective publications fulfilled the inclusion criteria, involving a total of 663 episodes of ovarian torsion...
April 2016: Pediatric Emergency Care
Marybelle Pe, Eitan Dickman, Mark Tessaro
A 13-year-old adolescent girl with chronic abdominal distention was referred to the pediatric emergency department after the outpatient workup suggested moderate ascites. Point-of-care ultrasonography performed by the emergency physicians ruled out ascites, instead demonstrating a well-circumscribed cystic mass subsequently identified as an ovarian mucinous cystadenoma.
February 2016: Pediatric Emergency Care
Bindiya Gupta, Kiran Guleria, Amita Suneja, Neelam B Vaid, Shalini Rajaram, Neelam Wadhwa
A retrospective study was conducted to review incidence, clinical practice, surgical management and histology of adolescent ovarian masses in order to audit and improve future practices. Complete hospital records of all adolescents between 10 and 20 years who had undergone surgery for ovarian masses were analysed between November 2006 to 2014. Parameters analysed were age, clinical features, diagnosis, operative procedure and histopathology. Ninety-four patients were included in the study and among them, 37 had non-neoplastic masses, 30 had benign neoplasms while 27 had malignant tumors...
May 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Seung-Hyuk Shim, Sun Joo Lee, Soo-Nyung Kim, Su Hyun Chae, Ji Young Lee
OBJECTIVE: To compare transvaginal versus conventional laparoscopy for dermoid cysts. STUDY DESIGN: We retrospectively analyzed all con-secutive patients with dermoid cysts who underwent transvaginal (n = 219) or conventional (n = 245) laparoscopy from 2007-2013 at our institution. Each group of patients was matched (1:1 ratio) for age, body mass index, previous surgical history, cyst diameter, bilaterality, and cystectomy/oophorectomy. Surgical outcomes were compared between the 2 groups...
November 2015: Journal of Reproductive Medicine
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