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https://www.readbyqxmd.com/read/29473395/-introduction-low-health-literacy-hl-is-an-obstacle-to-therapeutic-patient-education-tpe-especially-for-people-in-a-vulnerable-situation-who-are-also-at-greater-risk-of-chronic-illnesses-and-their-complications-it-therefore-seems-essential-to-rethink-tpe-programmes
#1
[Introduction: Low health literacy (HL) is an obstacle to therapeutic patient education (TPE), especially for people in a vulnerable situation, who are also at greater risk of chronic illnesses and their complications. It therefore seems essential to rethink TPE programmes in order to ensure greater equity based on analysis of the characteristics of HL interventions and their possible relationships with TPE.Methods: A scoping review of the literature was performed from November 2014 to January 2016 using the following search engines: MEDLINE/PubMed, EMBASE, PsycINFO, ERIC, OpenGrey, SUDOC, thèses.fr and BDSP and the following search terms: "health literacy", "Littératie en santé", "literacy", "Littératie", "numeracy", "numératie", "compétence en santé" combined with the keywords: "programme", "program", "intervention", "méthode", "method", "technique", "outil", "tool".Results: After selecting forty out of 206 studies, interventions were classified into two main types of specific interventions to promote comprehension of resources intended for patients and generally complex interventions designed to support and improve HL skills.Discussion: While the level of health literacy has an impact on TPE programme accessibility, TPE programmes need to be made more accessible and TPE must constitute an opportunity to address health literacy needs via its own specific modalities. Creating partnerships between social/educational and health settings might be an effective strategy to strengthen the interrelationships between HL and TPE, as might training that prepares caregivers-educators to improve patient HL.Conclusion].
Aurore Margat, Rémi Gagnayre, Pierre Lombrail, Vincent de Andrade, Sylvie Azogui-Levy
INTRODUCTION: Low health literacy (HL) is an obstacle to therapeutic patient education (TPE), especially for people in a vulnerable situation, who are also at greater risk of chronic illnesses and their complications. It therefore seems essential to rethink TPE programmes in order to ensure greater equity based on analysis of the characteristics of HL interventions and their possible relationships with TPE. METHODS: A scoping review of the literature was performed from November 2014 to January 2016 using the following search engines: MEDLINE/PubMed, EMBASE, PsycINFO, ERIC, OpenGrey, SUDOC, thèses...
January 30, 2018: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/29473392/-objective-over-recent-years-therapeutic-patient-education-has-become-part-of-dental-medicine-management-of-early-childhood-caries-known-to-be-a-very-common-chronic-disease-has-evolved-to-include-an-educational-dimension-the-objective-of-this-study-was-to-identify
#2
Thomas Marquillier, Thomas Trentesaux, Rémi Gagnayre
OBJECTIVE: Over recent years, therapeutic patient education has become part of dental medicine. Management of early childhood caries, known to be a very common chronic disease, has evolved to include an educational dimension. The objective of this study was to identify the levers and barriers to the development of formalized therapeutic education programmes and alternatives. METHODS: A comprehensive exploratory qualitative study was conducted between November 2015 and June 2016 on a targeted sample of 15 people aware of the problem of TPE in dentistry...
January 30, 2018: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/29473279/autism-spectrum-disorder-and-genetic-testing-parental-perceptions-and-decision-making
#3
Alyson E Hanish, Marlene Z Cohen, Lois J Starr
PURPOSE: Advances in genomic technology and research have led to genetic testing being recognized as an essential component of the etiological workup for children with autism spectrum disorder (ASD). Chromosomal microarray analysis (CMA) is a first-tier diagnostic test for patients with ASD, as recommended by the American College of Medical Genetics and other professional societies. An accurate underlying medical diagnosis for ASD has many potential benefits, including appropriate medical management, detailed therapeutic recommendations, and accurate recurrence risk...
February 23, 2018: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29473140/variance-of-the-global-signal-as-a-pretreatment-predictor-of-antidepressant-treatment-response-in-drug-na%C3%A3-ve-major-depressive-disorder
#4
Jiajia Zhu, Huanhuan Cai, Yonggui Yuan, Yingying Yue, Deguo Jiang, Ce Chen, Wei Zhang, Chuanjun Zhuo, Yongqiang Yu
Several behavioral and neuroimaging markers could be used to predict eventual antidepressant medication (ADM) outcomes in patients with major depressive disorder (MDD). However, these predictors are either subjective or complex, which has limited their clinical use. Thus, we aimed to identify an objective and easy-to-get marker to predict early therapeutic efficacy. Forty-seven drug-naïve patients with MDD and 47 age-, gender- and education-matched healthy controls underwent resting-state functional magnetic resonance imaging (fMRI) scans...
February 23, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29471839/controlled-education-of-patients-after-stroke-ceops-nurse-led-multimodal-and-long-term-interventional-program-involving-a-patient-s-caregiver-to-optimize-secondary-prevention-of-stroke-study-protocol-for-a-randomized-controlled-trial
#5
Anne-Marie Mendyk, Alain Duhamel, Yannick Bejot, Didier Leys, Laurent Derex, Olivier Dereeper, Olivier Detante, Pierre-Yves Garcia, Olivier Godefroy, Francisco Macian Montoro, Jean-Philippe Neau, Sébastien Richard, Thierry Rosolacci, Igor Sibon, Denis Sablot, Serge Timsit, Mathieu Zuber, Charlotte Cordonnier, Régis Bordet
BACKGROUND: Setting up a follow-up secondary prevention program after stroke is difficult due to motor and cognitive impairment, but necessary to prevent recurrence and improve patients' quality of life. To involve a referent nurse and a caregiver from the patient's social circle in nurse-led multimodal and long-term management of risk factors after stroke could be an advantage due to their easier access to the patient and family. The aim of this study is to compare the benefit of optimized follow up by nursing personnel from the vascular neurology department including therapeutic follow up, and an interventional program directed to the patient and a caregiving member of their social circle, as compared with typical follow up in order to develop a specific follow-up program of secondary prevention of stroke...
February 22, 2018: Trials
https://www.readbyqxmd.com/read/29469078/barriers-affecting-adherence-to-radiation-treatment-and-strategies-to-overcome-those-barriers
#6
R Rangarajan, K Jayaraman
BACKGROUND: The WHO defines adherence as the extent to which a patient's behavior coincides with recommendations from a health-care provider. Nonadherence to cancer treatment has a major impact on the therapeutic outcome. AIM OF THE STUDY: To assess the prevalence of nonadherence to radiation regimen and to analyze the factors that affect adherence to cancer treatment. MATERIALS AND METHODS: Patients receiving radiation treatment in our hospital were screened for adherence to appointment keeping and to the prescribed radiation regimen and patients who had unplanned treatment breaks during treatment were interviewed...
April 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29468929/tumor-derived-lactate-induces-m2-macrophage-polarization-via-the-activation-of-the-erk-stat3-signaling-pathway-in-breast-cancer
#7
Xianmin Mu, Wei Shi, Yue Xu, Che Xu, Ting Zhao, Biao Geng, Jing Yang, Jinshun Pan, Shi Hu, Chen Zhang, Juan Zhang, Chao Wang, Jiajia Shen, Yin Che, Zheng Liu, Yuanfang Lv, Hao Wen, Qiang You
Tumor-associated macrophages (TAM) are prominent components of tumor microenvironment (TME) and capable of promoting cancer progression. However, the mechanisms for the formation of M2-like TAMs remain enigmatic. Here, we show that lactate is a pivotal oncometabolite in the TME that drives macrophage M2-polarization to promote breast cancer proliferation, migration, and angiogenesis. In addition, we identified that the activation of ERK/ STAT3, major signaling molecules in the lactate signaling pathway, deepens our molecular understanding of how lactate educates TAMs...
February 22, 2018: Cell Cycle
https://www.readbyqxmd.com/read/29465873/-what-place-for-therapeutic-education-in-nephrology
#8
Anne Dufey Teso, Pascale Lefuel, Sophie de Seigneux, Aline Lassere-Moutet, Pierre-Yves Martin, Alain Golay
Chronic kidney disease (CKD) usually goes unrecognized for patients until late symptomatic stages. In preterminal CKD, extrarenal substitution methods are usually presented to patients. This is felt like a breakdown, implying major modifications of everyday life. Acquisition of health literacy is necessary for patients with CKD to become autonomous and increase their empowerment toward the disease. Therapeutic education in nephrology plays a major role in improving the care of CKD patients.
February 21, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29464336/current-concepts-in-joint-pain-in-knee-osteoarthritis
#9
REVIEW
K Mills, M Hübscher, H O'Leary, N Moloney
Joint pain attributable to osteoarthritis (OA) is complex and influenced by a myriad of factors beyond local joint pathology. Current practice continues to predominantly adopt a biomedical approach to OA despite emerging evidence of the importance of a more holistic approach. This paper will summarise evidence for the presence of multidimensional pain profiles in knee joint pain and the presence of subgroups characterized by systemic features such as psychological distress, high comorbidity load or sensitisation of the nervous system...
February 20, 2018: Der Schmerz
https://www.readbyqxmd.com/read/29463635/how-can-emergency-physicians-harness-the-power-of-new-technologies-in-clinical-practice-and-education
#10
EDITORIAL
Simon Carley, Simon Laing
As the Royal College of Emergency Medicine looks back on 50 years of progress towards the future it is clear that new and emerging technologies have the potential to substantially change the practice of emergency medicine. Education, diagnostics, therapeutics are all likely to change as algorithms, personalised medicine and insights into complexity become more readily available to the emergency clinician. This paper outlines areas of our practice that are already changing and speculates on how we might need to prepare our workforce for a technologically enhanced future...
March 2018: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29462379/a-cross-talk-between-microbiota-derived-short-chain-fatty-acids-and-the-host-mucosal-immune-system-regulates-intestinal-homeostasis-and-inflammatory-bowel-disease
#11
Pedro Gonçalves, João Ricardo Araújo, James P Di Santo
Gut microbiota has a fundamental role in the energy homeostasis of the host and is essential for proper "education" of the immune system. Intestinal microbial communities are able to ferment dietary fiber releasing short-chain fatty acids (SCFAs). The SCFAs, particularly butyrate (BT), regulate innate and adaptive immune cell generation, trafficing, and function. For example, BT has an anti-inflammatory effect by inhibiting the recruitment and proinflammatory activity of neutrophils, macrophages, dendritic cells, and effector T cells and by increasing the number and activity of regulatory T cells...
February 15, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29462054/we-re-not-just-horsing-around-creating-innovative-community-clinical-experiences-utilizing-diverse-opportunities
#12
Mashawna R Hamilton, Elizabeth Delaney, Kelly Hall
Community nursing clinical experiences are essential to the education of BSN prelicensure students. Because of limited traditional community clinical sites, faculty must identify innovative, nontraditional community sites that provide quality experiences. Faculty at Ohio University identified a unique opportunity to provide a multidisciplinary collaborative community clinical rotation in conjunction with the Center for Therapeutic Riding Center located at the Ohio Horse Park. Nineteen senior BSN students participated in a six-week community clinical experience caring for a variety of vulnerable populations participating in the therapeutic riding program...
March 2018: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29460218/hypoglycemia-in-type-2-diabetes-understanding-patients-and-physicians-knowledge-and-experience
#13
Simon J Fisher, Xingyue Huang, Manjiri Pawaskar, Edward A Witt, Swapnil Rajpathak, R Ravi Shankar, Silvio E Inzucchi
PURPOSE: The aim of the current study is to assess the patient and physician experience and knowledge of hypoglycemia in the management of type 2 diabetes (T2DM). METHODS: T2DM patients (N = 1002) completed questionnaires on hypoglycemia experience, familiarity, and fear. Their responses were compared across various antihyperglycemic treatment regimens; specifically, (1) insulin only or insulin combined with sulfonylurea [SU] and/or metformin, (2) SU only with/without metformin, and (3) neither insulin nor SU...
February 19, 2018: Endocrine
https://www.readbyqxmd.com/read/29459194/the-value-of-psychosocial-group-activity-in-nursing-education-a-qualitative-analysis
#14
Yun-Jung Choi
BACKGROUND: Nursing faculty often struggle to find effective teaching strategies for nursing students that integrate group work into nursing students' learning activities. OBJECTIVES: This study was conducted to evaluate students' experiences in a psychiatric and mental health nursing course using psychosocial group activities to develop therapeutic communication and interpersonal relationship skills, as well as to introduce psychosocial nursing interventions. METHODS: A qualitative research design was used...
February 12, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29458991/prevalence-of-the-risk-factors-for-qt-prolongation-and-associated-drug-drug-interactions-in-a-cohort-of-medical-inpatients
#15
Qasim Khan, Mohammad Ismail, Iqbal Haider, Zahid Ali
BACKGROUND/PURPOSE: Medical inpatients are at increased risk of QT interval prolongation due to multiple risk actors and QT prolonging drugs. This study aimed to identify the prevalence of risk factors for QT prolongation; QT prolonging medications; associated drug-drug interactions (QT-DDIs); their predictors; and TdP (torsades de pointes) risks of drugs. METHODS: This cohort study was carried out in medical wards of two tertiary hospitals in Khyber Pakhtunkhwa, Pakistan...
February 16, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29458344/the-desire-to-die-in-palliative-care-optimization-of-management-dedipom-a-study-protocol
#16
Kerstin Kremeike, Maren Galushko, Gerrit Frerich, Vanessa Romotzky, Stefanie Hamacher, Gary Rodin, Holger Pfaff, Raymond Voltz
BACKGROUND: A desire to die (DD) is frequent in palliative care (PC). However, uncertainty remains as to the appropriate therapeutic response. (Proactive) discussion of DD is not usually part of standard care. To support health practitioners' (HPs) reactions to a patient's DD, a training program has been developed, piloted and evaluated. Within this framework, a first draft of a semi-structured clinical interview schedule with prompts (CISP) has been developed, including recommendations for action to support HPs' self-confidence...
February 20, 2018: BMC Palliative Care
https://www.readbyqxmd.com/read/29454590/understanding-how-prostate-cancer-patients-value-the-current-treatment-options-for-metastatic-castration-resistant-prostate-cancer
#17
Tarik Benidir, Karen Hersey, Antonio Finelli, Rob Hamilton, Anthony M Joshua, Girish Kulkarni, Alexandre Zlotta, Neil Fleshner
Several new compounds are now available for castration resistant prostate cancer (CRPC). Individual costs range between $40,000 and $93,000 with mean survival extensions from 2.4 to 4.8 months. Currently, it remains unclear how patients with prostate cancer (PCa) value the effect of these therapies in the setting of CRPC. OBJECTIVE: To assess patient understanding of core cancer concepts, opinions on the cost and overall benefit of CRPC drugs, whether out-of-pocket costs would change opinions and whether patients would ultimately opt out of CRPC drug treatment for an end-of-life (EOL) premium...
February 14, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29452662/pathogenesis-of-follicular-lymphoma
#18
REVIEW
Tracy Lackraj, Rashmi Goswami, Robert Kridel
Follicular lymphoma (FL) is presented as a germinal centre B cell lymphoma that is characterized by an indolent clinical course, but remains - paradoxically - largely incurable to date. The last years have seen significant progress in our understanding of FL lymphomagenesis, which is a multi-step process beginning in the bone marrow with the hallmark t(14;18)(q32;q21) translocation. The pathobiology of FL is complex and combines broad somatic changes at the level of both the genome and the epigenome, the latter evidenced by highly recurrent mutations in chromatin-modifying genes such as KMT2D and CREBBP...
March 2018: Best Practice & Research. Clinical Haematology
https://www.readbyqxmd.com/read/29449028/collection-of-human-biological-samples-for-research-purpose-key-challenges-and-patients%C3%A2-perspectives
#19
Céline Verstuyft, Zeina Antoun, Dominique Deplanque
The development and the access to collections of human biological samples is one of the major challenges for health research. In recent years, biological resource centres (BRCs) have developed in such a way that they provide all activities relating to the handling of samples. In this context, France is undoubtedly a pioneering country, because most of the biological collections available were created on the basis of themed research projects, which involved a particular donor phenotype. The round table was an opportunity to emphasise the persistence of some pitfalls particularly in relation to ensuring the consistency of different regulatory pathways...
February 12, 2018: Thérapie
https://www.readbyqxmd.com/read/29440043/acupuncture-versus-medication-for-pain-management-a-cross-sectional-study-of-breast-cancer-survivors
#20
Ting Bao, Susan Q Li, Josh L Dearing, Lauren A Piulson, Christina M Seluzicki, Robert Sidlow, Jun J Mao
AIM OF THE STUDY: Breast cancer survivors who take aromatase inhibitors (AI) often suffer from chronic pain. Emerging evidence supports the use of acupuncture as an effective pain management strategy for this condition, but its acceptability among cancer survivors is unknown. We evaluated breast cancer survivors' preferences for acupuncture as compared with medication use and identified factors predictive of this preference. METHODS: We conducted a cross-sectional study among breast cancer survivors who were currently, or had been, taking an AI...
February 10, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
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