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overuse atrophy

R H Dressendorfer, C E Wade
In brief: Indicators of muscular injury from overtraining were studied in 12 male runners during a road race held over 20 days. Dally mileage averaged 17.3 miles per day, twice their regular training distance. Most of the runners reported persistent mild-to-moderate thigh muscle soreness or stiffness. Serum creatine kinase (CK), an enzymatic marker of muscle tissue injury, was elevated on mornings after running but returned to normal values when the runners rested for two days after day 10. Thigh circumference became significantly reduced during the race, suggesting that the unaccustomed high running mileage also produced thigh muscle atrophy...
November 1983: Physician and Sportsmedicine
Nagat Frara, Samir M Abdelmagid, Michael Tytell, Mamta Amin, Steven N Popoff, Fayez F Safadi, Mary F Barbe
BACKGROUND: Expression of the growth factor osteoactivin (OA) increases during tissue degeneration and regeneration, fracture repair and after denervation-induced disuse atrophy, concomitant with increased matrix metalloproteinases (MMPs). However, OA's expression with repetitive overuse injuries is unknown. The aim of this study was to evaluate: 1) OA expression in an operant rat model of repetitive overuse; 2) expression of MMPs; 3) inflammatory cytokines indicative of injury or inflammation; and 4) the inducible form of heat shock protein 70 (HSPA1A/HSP72) as the latter is known to increase during metabolic stress and to be involved in cellular repair...
January 18, 2016: BMC Musculoskeletal Disorders
Tzu-Hsien Lai, Ekaterina Protsenko, Yu-Chen Cheng, Marco L Loggia, Gianluca Coppola, Wei-Ta Chen
Headaches are universal experiences and among the most common disorders. While headache may be physiological in the acute setting, it can become a pathological and persistent condition. The mechanisms underlying the transition from episodic to chronic pain have been the subject of intense study. Using physiological and imaging methods, researchers have identified a number of different forms of neural plasticity associated with migraine and other headaches, including peripheral and central sensitization, and alterations in the endogenous mechanisms of pain modulation...
2015: Neural Plasticity
Seung Jun Seol, Seung Hoon Han
Scapulothoracic bursitis is a rare disease and presents as pain or swelling around the bursa of the scapulothoracic articulation. It has been reported to be related to chronic repetitive mechanical stress of the periscapular tissue, trauma, overuse, and focal muscle weakness. The authors experienced an atypical case of scapulothoracic bursitis with shoulder and periscapular pain after quadriparesis.This case implies that muscular atrophy around the scapula and chest wall from quadriparesis may contribute to the development of scapulothoracic bursitis with shoulder and periscapular pain...
April 2015: Medicine (Baltimore)
T Stein, J Buckup, T Efe, R von Eisenhart-Rothe, R Hoffmann, E Zimmermann, F Welsch
INTRODUCTION: Muscular recovery of structural integrity after arthroscopic Bankart repair using the para- and trans-musculotendinous three-portal technique has not been investigated. MATERIALS AND METHODS: Twenty-seven athletes [mean age 26.9 years, (group 1; G1)] were prospectively and longitudinally monitored after arthroscopic Bankart repair using the three-portal technique by magnetic resonance imaging (MRI) and specific clinical muscular testing. The muscular integrity was assessed at the subscapularis (SSC) for the para-tendinous anteroinferior portal, the supraspinatus (SSP) for the trans-tendinous suprabicipital portal, and the infraspinatus (ISP) for the trans-tendinous posterior portal...
March 2015: Archives of Orthopaedic and Trauma Surgery
Eva Cernuda-Morollón, César Ramón, Davinia Larrosa, Rocío Alvarez, Nuria Riesco, Julio Pascual
BACKGROUND: OnabotulinumtoxinA (onabotA) has shown its efficacy over placebo in chronic migraine (CM), but clinical trials lasted only up to one year. OBJECTIVE: The objective of this article is to analyse our experience with onabotA treatment of CM, paying special attention to what happens after one year. PATIENTS AND METHODS: We reviewed the charts of patients with CM on onabotA. Patients were injected quarterly during the first year but the fifth appointment was delayed to the fourth month to explore the need for further injections...
September 2015: Cephalalgia: An International Journal of Headache
John Karl L de Dios, Joseph A Shrader, Galen O Joe, Jeffrey C McClean, Kayla Williams, Robert Evers, May Christine V Malicdan, Carla Ciccone, Ami Mankodi, Marjan Huizing, John C McKew, David A Bluemke, William A Gahl, Nuria Carrillo-Carrasco
GNE myopathy is a rare autosomal recessive muscle disease caused by mutations in GNE, the gene encoding the rate-limiting enzyme in sialic acid biosynthesis. GNE myopathy usually manifests in early adulthood with distal myopathy that progresses slowly and symmetrically, first involving distal muscles of the lower extremities, followed by proximal muscles with relative sparing of the quadriceps. Upper extremities are typically affected later in the disease. We report a patient with GNE myopathy who presented with asymmetric hand weakness...
December 2014: Neuromuscular Disorders: NMD
R Buschbacher
The use of ankle bracing, taping, and wrapping for athletic injuries is both overused and underused. The overuse occurs in patients who don't need ankle support at all, or who don't need it anymore. Underuse occurs in patients who could potentially return to activity sooner with the extra support.It is now well established and accepted that prolonged immobilization of a body part brings with it a number of deleterious effects. Immobilized animals have been shown to have decreased strength of muscles, bones, tendons, and ligaments...
January 1, 1993: Journal of Back and Musculoskeletal Rehabilitation
Jesús Esteban
In 1875 M. Raymond described a progressive muscle wasting and weakness in 3 individuals survivors of childhood acute poliomyelitis. Jean-Martin Charcot suggested that the initial injury should let these guys neurons more sensitive to develop posterior spinal diseases and new weakness was the result of overuse of the affected muscles. In 1979, after the publication of the description given by a 57 year old patient on motor difficulties that developed after suffering of polio in childhood, there was a very significant increase of comments of other individuals with similar symptoms, reaching wedged in the 80s the term of post-polio syndrome...
September 2013: Revista Española de Salud Pública
Augustine H Conduah, Champ L Baker, Champ L Baker
CONTEXT: Symptomatic scapulothoracic bursitis and crepitus are disorders of the scapulothoracic articulation that are often poorly understood. They can be a source of persistent pain and dysfunction in the active overhead throwing athlete. It is important to distinguish between scapulothoracic bursitis and scapulothoracic crepitus. Scapulothoracic bursitis refers to inflammation of the bursae secondary to trauma or overuse owing to sports activities or work. Scapulothoracic crepitus is defined by a grinding, popping, or thumping sound or sensation secondary to abnormal scapulothoracic motion...
March 2010: Sports Health
J Facione, J M Beis, G T Kpadonou, D Lagauche, A Touillet, M Braun, L Le Chapelain, J Paysant
STUDY DESIGN: Case report. OBJECTIVES: To describe a case of suprascapular nerve entrapment (SNE) in a patient with a spinal cord injury (SCI) as a cause of shoulder pain. SETTING: Physical Medicine and Rehabilitation Institute, Nancy, France. REPORT: Six months after the occurrence of acute paraplegia T9 ASIA, a 45-year-old man complained of pain in the posterior and lateral areas of the left shoulder. A clinical assessment found an atrophy of the infraspinatus muscle and a muscular weakness during external shoulder rotation...
June 2011: Spinal Cord
Tiziana Pietrangelo, Cristina Puglielli, Rosa Mancinelli, Sara Beccafico, Giorgio Fanò, Stefania Fulle
Sarcopenia is the age-related loss of muscle mass, strength and function. Human muscle proteins are synthesized at a slower rate in the elderly than in young adults, leading to atrophy and muscle mass loss with a decline in the functional capability. Additionally, aging is accompanied by a decrease in the ability of muscle tissue to regenerate following injury or overuse due to the impairment of intervening satellite cells, in which we previously reported oxidative damage evidences. The aim of the present study was to determine the effects of aging on myoblasts and myotubes obtained from human skeletal muscle, and characterize the transcriptional profile as molecular expression patterns in relation to age-dependent modifications in their regenerative capacity...
August 2009: Experimental Gerontology
Sarah B Goldman, Teresa L Brininger, Amanda Antczak
NARRATIVE REVIEW: Patients with focal hand dystonia and upper extremity entrapment neuropathies may present with similar symptoms and risk factors making it difficult to distinguish between the two diagnoses. Evaluating for the presence of neuromuscular findings and abnormal movement patterns can help assist the hand therapist in identifying the presence of focal hand dystonia or peripheral motor axon involvement in the absence of pronounced muscle atrophy. The purposes of this review article are twofold. First, to describe selected neuromuscular signs and symptoms characteristic of patients presenting with repetitive overuse syndromes of the upper limb leading to either a nerve entrapment syndrome or a focal hand dystonia...
April 2009: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
Jeffrey C Y Chan, William H Tiong, Michael J Hennessy, John L Kelly
BACKGROUND: Occupational overuse syndrome (OOS) can present as Guyon's canal syndrome in computer keyboard users. We report a case of Guyon's canal syndrome caused by a ganglion in a computer user that was misdiagnosed as OOS. CASE PRESENTATION: A 54-year-old female secretary was referred with a six-month history of right little finger weakness and difficulty with adduction. Prior to her referral, she was diagnosed by her general practitioner and physiotherapist with a right ulnar nerve neuropraxia at the level of the Guyon's canal...
2008: Journal of Brachial Plexus and Peripheral Nerve Injury
Keitaro Kubo, Yoshie Ishida, Teruaki Komuro, Naoya Tsunoda, Hiroaki Kanehisa, Tetsuo Fukunaga
BACKGROUND: Recently, the number of elderly individuals who participate in sports has increased, thus injuries from overuse are now becoming recognized in the elderly population. Therefore, it is important to determine which muscle groups and tendons are most affected with aging to plan appropriate exercise interventions for elderly individuals. In particular, muscles and tendons in knee extensors and plantar flexors play an important role during locomotion. The purpose of this study was to compare the knee extensor and plantar flexor muscles and tendons...
November 2007: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
T Schmidt-Wilcke, E Leinisch, A Straube, N Kämpfe, B Draganski, H C Diener, U Bogdahn, A May
Using MRI and voxel-based morphometry, the authors investigated 20 patients with chronic tension type headache (CTTH) and 20 patients with medication-overuse headache and compared them to 40 controls with no headache history. Only patients with CTTH demonstrated a significant gray matter decrease in regions known to be involved in pain processing. The finding implies that the alterations are specific to CTTH rather than a response to chronic head pain or chronification per se.
November 8, 2005: Neurology
Mark Ling, Alice Gottlieb, David Pariser, Ivan Caro, Daniel Stewart, Graham Scott, Ken Abrams
BACKGROUND: Pimecrolimus cream 1% (Elidel), a non-steroid inhibitor of inflammatory cytokines, is effective in the treatment of atopic dermatitis, without corticosteroid-related side effects such as skin atrophy. It is indicated for twice-daily application. More frequent applications might be expected either to enhance efficacy or increase toxicity. This study compared the safety, efficacy and systemic absorption of pimecrolimus administered twice daily (recommended dose) and four times daily early in the treatment of patients with moderate to severe atopic dermatitis...
August 2005: Journal of Dermatological Treatment
Francisco Vázquez-López, Ashfaq A Marghoob
We investigated the value of the dermoscope for monitoring the long term safety of high potency topical steroids in patients with chronic psoriasis. We observed for the first time that the overuse of topical steroids resulted in the appearance of clinically unapparent but dermoscopically apparent "red lines" (linear telangiectasias) in the treated plaques and/or skin adjacent to the treated plaques (P < .03). We concluded that dermoscopy may help reveal the early signs of impending steroid-induced atrophy ("red lines") before they become clinically evident with the naked eye and before the atrophy becomes permanent...
November 2004: Journal of the American Academy of Dermatology
Tamir Pritsch, Yishai Rosenblatt, Avshalom Carmel
Carpal tunnel syndrome is the most common peripheral nerve compression syndrome. Compression of the median nerve in the carpal tunnel, disrupts the blood-nerve barrier causing edema, inflammation and fibrosis of its surrounding connective tissues. In the next stage of the syndrome there is a disruption of the myelin coverage of the nerve followed by damage to the axons. Most carpal tunnel syndromes are idiopathic. Other causes include intrinsic factors (which cause pressure within the tunnel), extrinsic factors (which cause pressure from outside the tunnel) and overuse/exertional factors...
October 2004: Harefuah
Bruk Jubelt
Post-polio syndrome (PPS) is the term used for the new late manifestations that occur in patients 30 to 40 years after the occurrence of acute poliomyelitis. PPS has been recognized for over 100 years, but is more common at the present time because of the large epidemics of poliomyelitis in the 1940s and 1950s. PPS is manifested by neurologic, musculoskeletal, and general manifestations. Neurologic manifestations include new weakness, muscle atrophy, dysphagia, dysphonia, and respiratory failure. Musculoskeletal manifestations include muscle pain, joint pain, spinal spondylosis and scoliosis, and secondary root and peripheral nerve compression...
March 2004: Current Treatment Options in Neurology
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