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Venous outflow obstruction

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https://www.readbyqxmd.com/read/28104116/outflow-reconstruction-using-cryopreserved-homologous-venous-grafts-in-living-donor-liver-transplantation
#1
K Ito, N Akamatsu, J Togashi, S Tamura, Y Sakamoto, K Hasegawa, N Kokudo
OBJECTIVES: The techniques and outcomes of outflow reconstruction in living donor liver transplantation (LDLT) using cryopreserved homologous veins at the University of Tokyo Hospital are presented. METHODS: We performed 540 LDLTs from January 1996 to March 2015. Graft types included right liver graft (n = 262), left liver graft (n = 196), left lateral sector graft (n = 53), and posterior sector graft (n = 28). We routinely use cryopreserved homologous vein grafts for the hepatic vein reconstructions to secure the large outflow of the graft...
January 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28025027/catheter-directed-thrombolysis-and-pharmacomechanical-thrombectomy-improve-midterm-outcome-in-acute-iliofemoral-deep-vein-thrombosis
#2
Tzu-Ting Kuo, Chun-Yang Huang, Chiao-Po Hsu, Chiu-Yang Lee
BACKGROUND: Aggressive and early thrombus removal strategy has been widely used as a treatment for iliofemoral deep vein thrombosis (DVT). We compared the long-tem venous outcome, including postthrombotic syndrome (PTS), in patients undergoing catheter-directed thrombolysis (CDT) and pharmacomechanical thrombectomy (PMT). METHODS: From January 2009 to December 2013, 61 patients with acute proximal DVT were enrolled in this prospective study. Thirty-one patients underwent CDT and 30 patients underwent PMT, and each patient was followed for at least 2 years after treatment...
December 23, 2016: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28018103/portal-hypertension-in-polycystic-liver-disease-patients-does-not-affect-wait-list-or-immediate-post-liver-transplantation-outcomes
#3
Neil Rajoriya, Dhiraj Tripathi, Joanna A Leithead, Bridget K Gunson, Sophie Lord, James W Ferguson, Gideon M Hirschfield
AIM: To establish the impact of portal hypertension (PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease (PCLD) listed for liver transplantation. METHODS: A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters: (1) presence of radiological or endoscopic documented varices from our own centre or the referral centre; (2) splenomegaly (> 11 cm) on radiology in absence of splenic cysts accounting for increased imaging size; (3) thrombocytopenia (platelets < 150 × 10(9)/L); or (4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst...
December 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27987620/validation-of-the-novel-venous-drainage-index-with-stepwise-increases-in-thigh-compression-pressure-in-the-quantification-of-venous-obstruction
#4
Christopher R Lattimer, Stephen Doucet, George Geroulakos, Evi Kalodiki
BACKGROUND: Venous drainage from the leg is poorly understood, and it is difficult to quantify it hemodynamically. Attempts have been made using duplex ultrasound scanning and venous occlusion air plethysmography (APG). However, they have limited value in day-to-day clinical practice. This is because venous drainage measurements have never been validated successfully against increasing obstruction pressures. The hypothesis is that the novel gravitational venous drainage index (VDI) in milliliters/second is reduced in response to increasing venous obstruction, and the aim was to quantify this, using stepwise inflations of a thigh cuff...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27987604/common-femoral-endovenectomy-in-conjunction-with-iliac-vein-stenting-to-improve-venous-inflow-in-severe-post-thrombotic-obstruction
#5
Himanshu Verma, Ramesh K Tripathi
Post-thrombotic syndrome secondary to iliofemoral deep venous thrombosis is a significant contributor to advanced chronic venous insufficiency. Iliac vein stenting is a standard procedure to treat iliocaval obstruction. In cases with obstruction extending across the groin, venous inflow for an iliac vein stent may be poor and compromise results of iliac vein stenting. Treatment options include extension of stents across the inguinal ligament that may have limitations in improving inflow only from only one vessel...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27903022/-recanalization-techniques-for-venous-outflow-obstruction
#6
Michael K W Lichtenberg, Houman Jalaie
Deep vein thrombosis (DVT) is associated with a high cost burden for health care systems because of secondary cost intensive complications like pulmonary embolism and especially the post thrombotic syndrome (PTS). The current standard therapy of anticoagulation for DVT therapy has not changed through the years leaving patients especially with iliofemoral vein thrombus on a high-risk situation for developing PTS. Current study situation for endovascular treatment of iliofemoral DVT treatment gives a rationale for active thrombus removal using catheter directed therapy (CDT) or pharmacomechanical thrombectomy (PMT) which improves valvular vein function and luminal patency reducing the potential complication of PTS...
November 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27876287/mid-term-outcomes-of-common-congenital-heart-defects-corrected-through-a-right-subaxillary-thoracotomy
#7
Guoying An, Hongyu Zhang, Shanguang Zheng, Weixin Wang, Liming Ma
OBJECTIVE: To evaluate the mid-term outcomes of the correction of various congenital heart defects through a right subaxillary thoracotomy. METHODS: Between June 2004 and April 2014, all eligible patients were those with a common congenital heart defect corrected via an approach through a right subaxillary thoracotomy. There were 836 patients (male 417, female 419; median age, 3.5 years; median weight 13.6kg) with ventricular septal defect (VSD) closure (523 patients), atrial septal defect (ASD) closure (235 patients), partial atrioventricular canal (PAVC) correction (55 patients), mild tetralogy of Fallot (TOF) (23 patients)...
February 17, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27767958/noncavernous-arteriovenous-shunts-mimicking-carotid-cavernous-fistulae
#8
Chai Kobkitsuksakul, Pakorn Jiarakongmun, Ekachat Chanthanaphak, Sirintara Pongpech
PURPOSE: The classic symptoms and signs of carotid cavernous sinus fistula or cavernous sinus dural arteriovenous fistula (AVF) consist of eye redness, exophthalmos, and gaze abnormality. The angiography findings typically consist of arteriovenous shunt at cavernous sinus with ophthalmic venous drainage with or without cortical venous reflux. In rare circumstances, the shunts are localized outside the cavernous sinus, but mimic symptoms and radiography of the cavernous shunt. We would like to present the other locations of the arteriovenous shunt, which mimic the clinical presentation of carotid cavernous fistulae, and analyze venous drainages...
November 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/27751879/can-preeclampsia-be-considered-a-renal-compartment-syndrome-a-hypothesis-and-analysis-of-the-literature
#9
David G Reuter, Yuk Law, Wayne C Levy, Stephen P Seslar, R Eugene Zierler, Mark Ferguson, James Chattra, Tim McQuinn, Lenna L Liu, Mark Terry, Patricia S Coffey, Jane A Dimer, Coral Hanevold, Joseph T Flynn, F Bruder Stapleton
The morbidity and mortality associated with preeclampsia is staggering. The physiology of the Page kidney, a condition in which increased intrarenal pressure causes hypertension, appears to provide a unifying framework to explain the complex pathophysiology. Page kidney hypertension is renin-mediated acutely and ischemia-mediated chronically. Renal venous outflow obstruction also causes a Page kidney phenomenon, providing a hypothesis for the increased vulnerability of a subset of women who have what we are hypothesizing is a "renal compartment syndrome" due to inadequate ipsilateral collateral renal venous circulation consistent with well-known variation in normal venous anatomy...
September 15, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27742430/non-contrast-enhanced-mr-angiography-in-the-diagnosis-of-budd-chiari-syndrome-bcs-compared-with-digital-subtraction-angiography-dsa-preliminary-results
#10
Chun Yang, Ceng Li, Mengsu Zeng, Xin Lu, Jingjing Li, Jiali Wang, Muhammad Umair Sami, Kai Xu
Non-CE MRA techniques (true steady-state free-precession, SSFP) have been used effectively for the selective visualization of the portal venous system and inferior vena cava. Budd-Chiari Syndrome (BCS) encompasses a number of conditions that cause the obstruction of the hepatic outflow tract from the small hepatic veins to the junction of the inferior vena cava (IVC) and right atrium. The purpose of this study was to diagnose BCS with IVC obstruction using respiratory triggered three-dimensional (3D) true SSFP with T-SLIP and compare to digital subtraction angiography (DSA)...
October 11, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27681331/the-spectrum-of-histologic-findings-in-hepatic-outflow-obstruction
#11
Raul S Gonzalez, Michael A Gilger, Won Jae Huh, Mary Kay Washington
CONTEXT: -Cardiac hepatopathy and Budd-Chiari syndrome are 2 forms of hepatic venous outflow obstruction with different pathophysiology but overlapping histologic findings, including sinusoidal dilation and centrilobular necrosis. OBJECTIVE: -To determine whether a constellation of morphologic findings could help distinguish between the 2 and could suggest the diagnoses in previously undiagnosed patients. DESIGN: -We identified 26 specimens with a diagnosis of cardiac hepatopathy and 23 with a diagnosis of Budd-Chiari syndrome...
January 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27656864/budd-chiari-syndrome-causing-acute-liver-failure-a-multicenter-case-series
#12
Justin Parekh, Vlad M Matei, Alejandro Canas-Coto, Daniel Friedman, William M Lee
BACKGROUND: Budd-Chiari syndrome (BCS) is a rare disease resulting from obstruction of the hepatic venous outflow tract that typically presents with abdominal pain, jaundice and ascites without frank liver failure. However, BCS may also evolve more rapidly to acute liver failure (ALF-BCS). AIMS: To describe the clinical features, treatment and outcomes of ALF due to BCS and compare our results with those in the published literature. METHODS: Twenty of the 2,300 patients enrolled in the Acute Liver Failure Study Group (ALFSG) registry since 1998, presented with a clinical diagnosis of BCS...
September 22, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/27634954/comparison-of-venous-sinus-manometry-gradients-obtained-while-awake-and-under-general-anesthesia-before-venous-sinus-stenting
#13
Kyle M Fargen, Alejandro M Spiotta, Madison Hyer, Jonathan Lena, Raymond D Turner, Aquilla S Turk, Imran Chaudry
INTRODUCTION: Venous sinus stenting is a popular treatment strategy for patients with high venous sinus pressure gradients across a site of outflow obstruction. Little is known about the effect of anesthesia on venous sinus pressure measurements. OBJECTIVE: To compare venous manometry performed in patients under general anesthesia and while awake. METHODS: A prospective database was accessed to retrospectively identify patients who had undergone venous sinus stenting...
September 15, 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27633031/low-frequency-of-v617f-mutation-in-jak2-gene-in-indian-patients-with-hepatic-venous-outflow-obstruction-and-extrahepatic-portal-venous-obstruction
#14
Praveer Rai, Pankaj Kumar, Swapnil Mishra, Rakesh Aggarwal
BACKGROUND: Hepatic venous outflow tract obstruction (HVOTO) and extrahepatic portal venous obstruction (EHPVO) are important causes of portal hypertension and related complications in India. Both these conditions result from splanchnic venous thrombosis. In recent years, a V617F somatic mutation in Janus kinase 2 (JAK2) gene which is highly specific for myeloproliferative disorders has been detected in 40 % to 50 % and 30 % to 35 % of Western patients with HVOTO and EHPVO, respectively...
September 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27621751/inferior-vena-cava-stenosis-induced-sinusoidal-obstructive-syndrome-after-living-donor-liver-transplantation
#15
Batsaikhan Bat-Erdene, Sergelen Orgoi, Erdene Sandag, Ulzii-Orshikh Namkhai, Bat-Ireedui Badarch, Batsaikhan Batsuuri
The sinusoidal obstructive syndrome (SOS) is a complication that usually follows hematopoietic stem cell transplantation. It is also known as veno-occlusive disease, which is a rare complication of living donor liver transplantation (LDLT). Herein, we reported a 34 year-old female patient presenting SOS after LDLT. Its underlying cause was presumed to be associated with liver abscess and subsequent inferior vena cava stenosis. SOS led to graft failure, thus requiring retransplantation with a deceased donor liver graft...
August 2016: Korean Journal of Hepato-biliary-pancreatic Surgery
https://www.readbyqxmd.com/read/27516340/long-term-outcomes-of-stent-placement-for-hepatic-venous-outflow-obstruction-in-adult-liver-transplantation-recipients
#16
Hee Ho Chu, Nam-Joon Yi, Hyo-Cheol Kim, Kwang-Woong Lee, Kyung-Suk Suh, Hwan Jun Jae, Jin Wook Chung
The purpose of this study was to evaluate the long-term outcomes of stent placement for a hepatic venous outflow obstruction in adult liver transplantation recipients. From June 2002 to March 2014, 23 patients were confirmed to have a hepatic venous outflow obstruction after liver transplantation (18 of 789 living donors [2.3%] and 5 of 449 deceased donors [1.1%]) at our institute. Among these patients, 16 stenotic lesions in 15 patients (12 males, 3 females; mean age: 51.7 years) underwent stent placement...
August 12, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/27507647/characteristics-of-hepatocellular-carcinoma-in-egyptian-patients-with-primary-budd-chiari-syndrome
#17
Mohammad Sakr, Sara M Abdelhakam, Hany Dabbous, Amr Hamed, Zeinab Hefny, Waleed Abdelmoaty, Mohamed Shaker, Mohamed Elgharib, Ahmed Eldorry
BACKGROUND AND AIM: Budd-Chiari syndrome (BCS) is caused by hepatic venous outflow obstruction. This work aimed at analyzing characteristics and factors associated with development of hepatocellular carcinoma (HCC) in patients with primary BCS. METHODS: 348 Egyptian BCS patients were included. They were presented to the Budd-Chiari Study Group of Ain Shams University Hospital. BCS was confirmed using abdominal Doppler US. Abdominal magnetic resonance imaging (MRI), MR venography, and/or multislice computed tomography (CT) were performed to confirm all diagnoses and to assess vascular anatomy...
August 10, 2016: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/27471977/imaging-of-intracranial-pressure-disorders
#18
John Holbrook, Amit M Saindane
: Intracranial pressure (ICP) is the pressure inside the bony calvarium and can be affected by a variety of processes, such as intracranial masses and edema, obstruction or leakage of cerebrospinal fluid, and obstruction of venous outflow. This review focuses on the imaging of 2 important but less well understood ICP disorders: idiopathic intracranial hypertension and spontaneous intracranial hypotension. Both of these ICP disorders have salient imaging findings that are important to recognize to help prevent their misdiagnosis from other common neurological disorders...
July 27, 2016: Neurosurgery
https://www.readbyqxmd.com/read/27467004/budd-chiari-syndrome-current-perspectives-and-controversies
#19
L Liu, X-S Qi, Y Zhao, H Chen, X-C Meng, G-H Han
Budd-Chiari syndrome (BCS) is a rare disorder caused by hepatic venous outflow obstruction with a wide spectrum of etiologies. Clinical manifestations are so heterogeneous that the diagnosis should be considered in any patients with acute or chronic liver disease. Therapeutic modalities for BCS have improved dramatically during the last few years. The concept of a step-wise treatment strategy has been established, including anticoagulation, thrombolysis, percutaneous recanalization, transjugular intrahepatic portosystemic shunt, surgery and liver transplantation...
July 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27444939/validation-of-a-hemodynamic-model-for-the-study-of-the-cerebral-venous-outflow-system-using-mr-imaging-and-echo-color-doppler-data
#20
G Gadda, A Taibi, F Sisini, M Gambaccini, S K Sethi, D T Utriainen, E M Haacke, P Zamboni, M Ursino
BACKGROUND AND PURPOSE: A comprehensive parameter model was developed to investigate correlations between cerebral hemodynamics and alterations in the extracranial venous circulation due to posture changes and/or extracranial venous obstruction (stenosis). The purpose of this work was to validate the simulation results by using MR imaging and echo-color Doppler experimental blood flow data in humans. MATERIALS AND METHODS: To validate the model outcomes, we used supine average arterial and venous extracerebral blood flow, obtained by using phase-contrast MR imaging from 49 individuals with stenosis in the acquisition plane at the level of the disc between the second and third vertebrae of the left internal jugular vein, 20 with stenosis in the acquisition plane at the level of the disc between the fifth and sixth vertebrae of the right internal jugular vein, and 38 healthy controls without stenosis...
July 21, 2016: AJNR. American Journal of Neuroradiology
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