keyword
https://read.qxmd.com/read/38644302/-current-status-and-issues-of-companion-diagnostics-in-cancer-genomic-medicine
#1
JOURNAL ARTICLE
Masashi Kanai
As of December 2023, there are 5 types of cancer gene panel tests covered by public insurance in Japan. Four of them partly feature companion diagnostics. When cancer gene panel test is used for the purpose of comprehensive gene profiling (CGP), a total of 56,000 points(44,000 points for the test administration fee and 12,000 points for the expert panel fee) can be claimed, whereas if the cancer gene panel test is used for the purpose of companion diagnostics, hospitals can claim only the reimbursement as a companion diagnostics, which fee is much cheaper than that of CGP...
April 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38644300/-current-status-and-issues-of-companion-diagnostics-for-non-small-cell-lung-cancer
#2
JOURNAL ARTICLE
Miyako Satouchi
There have been many driver gene abnormalities identified in NSCLC, and the development and clinical adoption of targeting drugs for such are progressing. This has, as a result, complicated the situation surrounding companion diagnostics (CDx). Lung cancer treatment guidelines recommend the use of Multiplex testing that allow for CDx for many driver gene abnormalities to be used prior to 1L treatment for advanced lung cancer. The problem is that insurance rules stipulate that only one of Multiplex test is deemed reimbursable per junction in time, particular CDx are linked to particular targeted drugs instead of particular driver gene abnormalities, and none of the currently available Multiplex tests contain the CDx for all genetic mutations for which drugs have been approved...
April 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38643103/tailoring-remote-patient-management-in-cardiovascular-risk-management-for-healthcare-professionals-using-panel-management-a-qualitative-study
#3
JOURNAL ARTICLE
Margot Rakers, Nicoline van Hattem, Iris Simic, Niels Chavannes, Petra van Peet, Tobias Bonten, Rimke Vos, Hendrikus van Os
BACKGROUND: While remote patient management (RPM) has the potential to assist in achieving treatment targets for cardiovascular risk factors in primary care, its effectiveness may vary among different patient subgroups. Panel management, which involves proactive care for specific patient risk groups, could offer a promising approach to tailor RPM to these groups. This study aims to (i) assess the perception of healthcare professionals and other stakeholders regarding the adoption and (ii) identify the barriers and facilitators for successfully implementing such a panel management approach...
April 20, 2024: BMC Prim Care
https://read.qxmd.com/read/38641801/cost-of-care-pathways-before-and-after-appropriate-and-inappropriate-transfers-to-the-emergency-department-among-nursing-home-residents-results-from-the-fine-study
#4
JOURNAL ARTICLE
E Gombault-Datzenko, N Costa, M Mounié, N Tavassoli, C Mathieu, H Roussel, J M Lagarrigue, E Berard, Y Rolland, L Molinier
BACKGROUND: Transfers of nursing home (NH) residents to the emergency department (ED) is frequent. Our main objective was to assess the cost of care pathways 6 months before and after the transfer to the emergency department among NH residents, according to the type of transfer (i.e. appropriate or inappropriate). METHODS: This was a part of an observational, multicenter, case-control study: the Factors associated with INappropriate transfer to the Emergency department among nursing home residents (FINE) study...
April 19, 2024: BMC Geriatrics
https://read.qxmd.com/read/38633222/selection-of-proxy-indicators-estimating-the-appropriateness-of-antibiotic-prescriptions-in-general-practice-a-national-consensus-procedure-in-france
#5
JOURNAL ARTICLE
Maïa Simon, Aurélie Bocquier, Ouarda Pereira, Alexandre Charmillon, Damien Gonthier, Florence Lieutier Colas, Camille Vallance, Adeline Welter, Céline Pulcini, Nathalie Thilly
BACKGROUND: GPs are responsible for more than 70% of outpatient antibiotic prescriptions in France. Metrics are important antibiotic stewardship tools that can be used to set targets for improvement and to give feedback to professionals and stakeholders. OBJECTIVES: The primary objective of the present study was to select a set of proxy indicators (PIs) based on 10 previously developed PIs, to estimate the appropriateness of antibiotic prescriptions by GPs. The secondary objective was to evaluate the clinimetric properties of the selected PIs...
April 2024: JAC-antimicrobial resistance
https://read.qxmd.com/read/38632895/impact-of-an-expanded-reimbursement-policy-on-utilization-of-implantable-loop-recorders-in-patients-with-cryptogenic-stroke-in-korea
#6
JOURNAL ARTICLE
Hye Bin Gwag, Nak Gyeong Ko, Mihyeon Jin
BACKGROUND/AIMS: The reimbursement policy for cryptogenic stroke (CS) was expanded in November 2018 from recurrent strokes to the first stroke episode. No reports have demonstrated whether this policy change has affected trends in implantable loop recorder (ILR) utilization. METHODS: We identified patients who received an ILR implant using the Korea Health Insurance Review and Assessment Service database between July 2016 and October 2021. Patients meeting all the following criteria were considered to have CS indication: 1) prior stroke history, 2) no previous history of atrial fibrillation or flutter (AF/AFL), and 3) no maintenance of oral anticoagulant for ≥4 weeks within a year before ILR implant...
April 18, 2024: Korean Journal of Internal Medicine
https://read.qxmd.com/read/38630536/a-roadmap-for-using-causal-inference-and-machine-learning-to-personalize-asthma-medication-selection
#7
JOURNAL ARTICLE
Flory L Nkoy, Bryan L Stone, Yue Zhang, Gang Luo
Inhaled corticosteroid (ICS) is a mainstay treatment for controlling asthma and preventing exacerbations in patients with persistent asthma. Many types of ICS drugs are used, either alone or in combination with other controller medications. Despite the widespread use of ICSs, asthma control remains suboptimal in many people with asthma. Suboptimal control leads to recurrent exacerbations, causes frequent ER visits and inpatient stays, and is due to multiple factors. One such factor is the inappropriate ICS choice for the patient...
April 17, 2024: JMIR Medical Informatics
https://read.qxmd.com/read/38627874/survey-on-value-elements-provided-by-artificial-intelligence-and-their-eligibility-for-insurance-coverage-with-an-emphasis-on-patient-centered-outcomes
#8
JOURNAL ARTICLE
Hoyol Jhang, So Jin Park, Ah-Ram Sul, Hye Young Jang, Seong Ho Park
OBJECTIVE: This study aims to explore the opinions on the insurance coverage of artificial intelligence (AI), as categorized based on the distinct value elements offered by AI, with a specific focus on patient-centered outcomes (PCOs). PCOs are distinguished from traditional clinical outcomes and focus on patient-reported experiences and values such as quality of life, functionality, well-being, physical or emotional status, and convenience. MATERIALS AND METHODS: We classified the value elements provided by AI into four dimensions: clinical outcomes, economic aspects, organizational aspects, and non-clinical PCOs...
March 20, 2024: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://read.qxmd.com/read/38624183/maternal-anaemia-prevention-and-control-in-china-a-policy-review
#9
REVIEW
Xiaoxi Liu, Xiaona Huang, Yuning Yang, Anuradha Narayan, Lidan Du-Skabrin, Xue Ding, Yongchao Chen, Jun Zhao, Suying Chang, Fang Wang
Maternal anaemia is a major public health problem. Developing maternal anaemia prevention and control policies is an important prerequisite for carrying out evidence-based interventions. This article reviews maternal anaemia prevention and control policies in China, identifies gaps, and provides references for other countries. We examined policies concerning maternal nutrition and other related literature in China, identified through key databases and government websites, and conducted a narrative review of the relevant documentations guided by the Smith Policy-Implementing-Process framework...
April 16, 2024: Maternal & Child Nutrition
https://read.qxmd.com/read/38622673/pregnancy-period-and-early-life-risk-factors-for-inflammatory-bowel-disease-a-northern-finland-birth-cohort-1966-study
#10
JOURNAL ARTICLE
Timo M Blomster, Olli-Pekka Koivurova, Ritva Koskela, Karl-Heinz Herzig, Nicholas J Talley, Jukka Ronkainen
BACKGROUND: The pathogenesis of inflammatory bowel disease (IBD) has not been fully elucidated. The aim of this study was to analyze the pregnancy period, perinatal period, and infancy period risk factors for IBD in a well-characterized birth cohort from Northern Finland. METHODS: The Northern Finland Birth Cohort 1966 (NFBC1966) population comprises mothers living in the two northernmost provinces of Finland, Oulu, and Lapland, with dates of delivery between Jan 1st and Dec 31st, 1966 (12 055 mothers, 12 058 live-born children, 96...
April 15, 2024: BMC Public Health
https://read.qxmd.com/read/38622559/a-pathway-study-of-factors-influencing-quality-of-fertility-life
#11
JOURNAL ARTICLE
Abulizi Maierhaba, Ming Jiang, Lihuan Zhi, Xueyu Wei, Lijuan He, Li Wang
BACKGROUD: To investigate the factors influencing fertility quality of life in infertile men, constructing a structural equation model of the factors influencing fertility quality of life in infertile men, and to provide suggested measures for improving fertility quality of life in infertile men. METHODS: It is a Observational study. Infertile men (n = 250) attending a fertility centre in a hospital in Xinjiang, matched 1:2 men with no obvious male factor in the control group (n = 500)...
April 15, 2024: BMC Public Health
https://read.qxmd.com/read/38605588/patient-experiences-using-public-and-private-insurance-coverage-for-abortion-in-illinois-implementation-successes-and-remaining-gaps
#12
JOURNAL ARTICLE
Madeline Quasebarth, Madeleine Boesche, Tecora Turner, Amy Moore, Danielle Young, Debra Stulberg, Lee Hasselbacher
CONTEXT: Insurance coverage for abortion in states where care remains legal can alleviate financial burdens for patients and increase access. Recent policy changes in Illinois required Medicaid and some private insurance plans to cover abortion care. This study explores policy implementation from the perspectives of patients using their insurance to obtain early abortion care. METHODOLOGY: Between July 2021 and February 2022, we interviewed Illinois residents who recently sought abortion care at ≤11 weeks of pregnancy...
April 11, 2024: Perspectives on Sexual and Reproductive Health
https://read.qxmd.com/read/38595923/cost-effectiveness-of-immune-checkpoint-inhibitors-in-treating-metastatic-urothelial-cancer
#13
JOURNAL ARTICLE
Li-Yu Yang, Jian-Ri Li, Chuan-Shu Chen, Chen-Li Cheng, Sheng-Chun Hung, Kun-Yuan Chiu, Cheng-Kuang Yang, Chiann-Yi Hsu, Shian-Shiang Wang
Objectives: Immune checkpoint inhibitor (ICI) is an important treatment option for metastatic urothelial carcinoma (mUC) patients. A lot of clinical evidence proved the survival benefits of ICI, but cost-effectiveness of the treatment remains unclear. This study evaluates the cost-effectiveness of the ICIs treatment in different sequences among mUC patients. Methods: We retrospectively analyzed mUC patients who had been treated at our hospital between January 2016 and December 2020. These patients received chemotherapy with or without ICI treatment (Pembrolizumab, Atezolizumab, Nivolumab, Durvalumab, or Avelumab)...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38595115/self-pay-outpatient-mental-health-care-for-children-and-adolescents-by-socioeconomic-status
#14
JOURNAL ARTICLE
Lindsay N Overhage, Nicole M Benson, Michael W Flores, Benjamin Lê Cook
OBJECTIVE: Many parents struggle to find mental health care for their children, and many mental health clinicians do not accept insurance payments. The authors aimed to estimate the frequency and cost of self-pay psychotherapy and psychotropic medication management visits for youths and to determine how service use varies by family income. METHODS: A descriptive cross-sectional analysis was performed among youths ages 5-17 years in the 2018-2020 Medical Expenditure Panel Survey...
April 10, 2024: Psychiatric Services: a Journal of the American Psychiatric Association
https://read.qxmd.com/read/38591000/lack-of-physician-dentist-collaboration-in-aspiration-pneumonia-prevention
#15
JOURNAL ARTICLE
Taiju Miyagami, Satoshi Teranaka, Yuichiro Mine, Tomohiro Matsumoto, Yuki Yoshimatsu, Shinichi Matsumoto, Kohei Yamaguchi, Toru Morikawa
This opinion paper addresses the challenges and future directions for preventing aspiration pneumonia in Japan's rapidly aging population. It highlights the increasing proportion of elderly individuals and the associated rise in health issues like decreased swallowing function, a risk factor for aspiration pneumonia. The paper emphasizes the effectiveness of dentist-provided oral care in preventing this condition but notes the lack of collaboration between dentists and physicians in Japan's clinical practice...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38590457/content-and-duration-of-doctor-patient-communication-in-outpatient-oncology-follow-up-consultations-in-china
#16
JOURNAL ARTICLE
Yinxia Zhan, Peiyang Mao, Feng Gao, Qiuling Shi
Purpose This study aimed to analyze the content of counseling between cancer patients and physicians during outpatient follow-up, assess the duration of different communication content, and explore the influencing factors. Patients and methods We observed consecutive cancer patients without a first diagnosis of malignancy who presented to the oncology outpatient clinic of a public hospital from October through December 2023. A structured observation form was used to record the content and duration of doctor-patient communication...
March 2024: Curēus
https://read.qxmd.com/read/38579082/survey-on-the-current-usage-of-ultrasound-guided-procedures-in-korean-medicine-clinics-and-hospitals
#17
JOURNAL ARTICLE
Ju Yeon Kim, Jung Min Yun, Sook-Hyun Lee, Yoon Jae Lee, Dong Kun Ko, In Heo, Woo-Chul Shin, Jae-Heung Cho, Byung-Kwan Seo, In-Hyuk Ha
Ultrasound-guidance is applied during the administration of Korean medicine (KM) interventions to improve the safety and effectiveness of the interventions. Although many case series and reports on the use of ultrasound-guided KM interventions have been reported, no study has investigated the current use of ultrasound-guidance in clinical practice by doctors of Korean medicine (KMDs). An online survey was conducted with questions examining the status of ultrasound-guidance usage among KMDs practicing in various KM clinical settings...
April 5, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38571364/medical-insurance-representatives-perceptions-on-national-health-insurance-primary-healthcare-re-engineering-in-south-africa-a-qualitative-study
#18
JOURNAL ARTICLE
Vivian Naidoo, Fatima Suleman, Varsha Bangalee
The South African government is moving toward universal health coverage (UHC) with the passing of the National Health Insurance (NHI) Bill. Access to quality primary healthcare (PHC) is the cornerstone of UHC principles. The South African governmental health department have begun focusing efforts on improving the efficiency and functionality of this system; that includes the involvement of private healthcare professionals and medical insurance companies. This study sought to explore perceptions of medical insurance company personnel on PHC re-engineering as part of NHI restructuring...
2024: Journal of Primary Care & Community Health
https://read.qxmd.com/read/38567887/single-use-duodenoscope-the-cleaner-standard
#19
JOURNAL ARTICLE
Chandana Lanka, Prashant Bhenswala, Muhddesa Lakhana, Neal C Shah, Pranay Srivastava, Iman Andalib, Frank Gress
Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard in the endoscopic management of biliary disease. An average of 700,000 ERCPs are performed every year, and most are performed using a reusable flexible duodenoscope. The innovation of disposable duodenoscopes has changed the dynamic in the advanced endoscopy field of study to primarily reduce or eliminate the risk of cross-contamination between patients. Many factors affect whether institutions can convert from standard reusable duodenoscopes to single-use duodenoscopes including the cost of the devices, reimbursement from insurance companies for the new devices, and the overall environmental impact...
April 1, 2024: Journal of Clinical Gastroenterology
https://read.qxmd.com/read/38565482/a-retrospective-study-of-orthognathic-surgery-reimbursement-and-volume-changes-at-an-american-academic-medical-center-over-a-13-year-period
#20
JOURNAL ARTICLE
Andrew J Deek, Devin J Clegg, Caleb Blackburn, Patricia Ne Roberson, Tyler Holley, Jack E Gotcher
OBJECTIVE: This study aimed to measure the association between orthognathic surgeon reimbursement and surgical volume over time. STUDY DESIGN: A retrospective cohort study of patients who underwent orthognathic surgery from January 1, 2010, to December 23, 2022, at an academic medical center was performed. Five patients per year were randomly selected and evaluated for insurance type and associated costs to create representative averages. Pearson correlation analysis was performed to test associations over 13 years with 2-tailed significance reported and statistical significance set at P < ...
February 17, 2024: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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