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https://www.readbyqxmd.com/read/29154919/patient-reported-outcomes-and-opioid-use-by-outpatient-cancer-patients
#1
N Moryl, V Dave, P Glare, A Bokhari, V T Malhotra, A Gulati, J Hung, V Puttanniah, Y Griffo, R Tickoo, A Wiesenthal, S D Horn, C E Inturrisi
The Memorial Sloan-Kettering Pain Registry contains patient characteristics, treatments, and outcomes for a prospective cohort of 1534 chronic pain cancer patients who were seen at outpatient pain service clinics. Average pain intensity (Brief Pain Inventory) was reported as mild by 24.6% of patients, moderate by 41.5%, and severe by 33.9%. The patient's report of average percent pain relief and health state (EQ-5D) was inversely related to average pain intensity category, while measures of pain interference, number of worst pain locations, and physical and psychological distress were directly related to pain intensity category...
November 14, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29154502/if-it-is-absurd-then-why-do-you-do-it-the-richer-the-obsessional-experience-the-more-compelling-the-compulsion
#2
Steffen Moritz, Christine Purdon, Lena Jelinek, Brenda Chiang, Marit Hauschildt
Mounting evidence suggests that obsessive intrusions are often accompanied and amplified by perceptual experiences of different modalities (e.g., feeling dirt on one's skin while experiencing intrusive thoughts about contamination). Pilot studies conducted online with individuals endorsing mild obsessive-compulsive symptoms have linked the co-occurrence of perceptual experiences and obsessions to the severity of subsequent compulsive behaviour as well as low insight. However, it is presently unclear whether sensory experiences accompany all types of obsessional thoughts or are restricted to certain preoccupations (e...
November 20, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/29149855/increasing-upper-limb-training-intensity-in-chronic-stroke-using-embodied-virtual-reality-a-pilot-study
#3
Daniel Perez-Marcos, Odile Chevalley, Thomas Schmidlin, Gangadhar Garipelli, Andrea Serino, Philippe Vuadens, Tej Tadi, Olaf Blanke, José D R Millán
BACKGROUND: Technology-mediated neurorehabilitation is suggested to enhance training intensity and therefore functional gains. Here, we used a novel virtual reality (VR) system for task-specific upper extremity training after stroke. The system offers interactive exercises integrating motor priming techniques and embodied visuomotor feedback. In this pilot study, we examined (i) rehabilitation dose and training intensity, (ii) functional improvements, and (iii) safety and tolerance when exposed to intensive VR rehabilitation...
November 17, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29148865/metronomic-therapy-has-low-toxicity-and-is-as-effective-as-current-standard-treatment-for-recurrent-high-risk-neuroblastoma
#4
Frank Berthold, Marc Hömberg, Inna Proleskovskaya, Pavel Mazanek, Margarita Belogurova, Angela Ernst, Jaroslav Sterba
The metronomic therapy concept uses low doses of continuously applied chemotherapeutic, anti-angiogenetic, and immunomodulating drugs. Twenty patients with recurrent and 3 with refractory high-risk neuroblastoma were treated by the metronomic concept using celecoxib, cyclophosphamide, vinblastine, and etoposide for up to 24 months. The outcome was compared to 274 matched patients with a first recurrence from stage 4 neuroblastoma using the variables time from diagnosis to first recurrence, number of organs involved, and MYCN amplification...
November 17, 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/29148332/medicare-advantage-and-traditional-medicare-hospitalization-intensity-and-readmissions
#5
Rachel Mosher Henke, Zeynal Karaca, Teresa B Gibson, Eli Cutler, Marguerite L Barrett, Katharine Levit, Jayne Johann, Lauren Hersch Nicholas, Herbert S Wong
Medicare Advantage plans have incentives and tools to optimize patient care. Therefore, Medicare Advantage hospitalizations may have lower cost and higher quality than similar traditional Medicare hospitalizations. We applied a coarsened matching approach to 2013 Healthcare Cost and Utilization Project hospital discharge data from 22 states to compare hospital cost, length of stay, and readmissions for Traditional Medicare and Medicare Advantage. We found that Medicare Advantage hospitalizations were substantially less expensive and shorter for mental health stays but costlier and longer for injury and surgical stays...
March 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29145407/predicting-mortality-and-hospitalization-of-older-adults-by-the-multimorbidity-frailty-index
#6
Yao-Chun Wen, Liang-Kung Chen, Fei-Yuan Hsiao
BACKGROUND: Existing operational definitions of frailty are personnel-costly and time-consuming, resulting in estimates with a small sample size that cannot be generalized to the population level. The objectives were to develop a multimorbidity frailty index using Taiwan's claim database, and to understand its ability to predict adverse event. METHODS: This is a retrospective cohort study. Subjects aged 65 to 100 years who have full National Health Insurance coverage in 2005 were included...
2017: PloS One
https://www.readbyqxmd.com/read/29144107/safe-return-to-driving-following-severe-acquired-brain-injury-role-of-a-short-neuropsychological-assessment
#7
Donatella Saviola, Antonio DE Tanti, Jessica Conforti, Lucio Posteraro, Alessia Manfredini, Chiara Bagattini, Benedetta Basagni
BACKGROUND: Driving is a complex ability requiring a broad range of motor, cognitive- behavioural and visual skills that may be impaired after severe Acquired Brain Injury (sABI). Resumption of driving is perceived as a major need by patients, being closely linked to personal autonomy, work and social activities. AIM: The objective of this study was to identify a short battery of neuropsychological tests with predictive value with regard to safe return to driving after sABI...
November 16, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29139162/epidemiology-of-therapeutic-apheresis-with-a-multidisciplinary-approach-at-a-high-volume-pediatric-center
#8
Rachel M Sirignano, Matthew L Paden, Ross Fasano, Erin K Meyer
INTRODUCTION: Therapeutic apheresis (TA) is used inconsistently in pediatric populations. We seek to define our multidisciplinary institutional practice. METHODS: We conducted a retrospective chart review of patients receiving TA from January 1, 2012 through October 31, 2015. Data collected included demographics, American Society of Apheresis (ASFA) indication, complications, and mortality. RESULTS: Over 46 months, 1198 TA procedures were conducted on 289 patients ranging in age from 5 months to 21 years with weights ranging from 4...
November 15, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/29137561/mental-health-spending-and-intensity-of-service-use-among-individuals-with-diagnoses-of-eating-disorders-following-federal-parity
#9
Haiden A Huskamp, Hillary Samples, Scott E Hadland, Emma E McGinty, Teresa B Gibson, Howard H Goldman, Susan H Busch, Elizabeth A Stuart, Colleen L Barry
OBJECTIVE: The Mental Health Parity and Addiction Equity Act (MHPAEA) was intended to eliminate differences in insurance coverage for mental health and substance use disorder services and medical-surgical care. No studies have examined mental health service use after federal parity implementation among individuals with diagnoses of eating disorders, for whom financial access to care has often been limited. This study examined whether MHPAEA implementation was associated with changes in use of mental health services and spending in this population...
November 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29132440/influence-of-successful-periodontal-intervention-in-renal-disease-inspired-study-protocol-for-a-randomised-controlled-pilot-clinical-trial
#10
Praveen Sharma, Paul Cockwell, Thomas Dietrich, Charles Ferro, Natalie Ives, Iain L C Chapple
BACKGROUND: Patients with chronic kidney disease (CKD) exhibit increased morbidity and mortality which is associated with an increased systemic inflammatory burden. Identifying and managing comorbid diseases that contribute to this load may inform novel care pathways that could have a beneficial impact on the morbidity/mortality associated with CKD. Periodontitis, a highly prevalent, chronic inflammatory disease affecting the supporting structures of teeth, is associated with an increased systemic inflammatory and oxidative stress burden and the successful treatment of periodontitis has been shown to reduce both...
November 13, 2017: Trials
https://www.readbyqxmd.com/read/29128470/is-it-worth-it-or-possible-to-measure-what-matters-to-patients-with-epilepsy-and-their-caregivers
#11
Maria Grazia Celani, Teresa Anna Cantisani, Angelo Bignamini, Sara Macone, Rossella Papetti, Luisa Baiocco
OBJECTIVE: The objective of this study was to collect perspectives, ideas, and values of people affected by epilepsy and their carer to include them in new research in this area. DESIGN: This is a semiquantitative study analyzing needs, emotions, and medical issues emerging from focus groups with patients and carers divided in three severity levels of disease. PARTICIPANTS: The participants were 25 patients and 36 carers attending outpatients' service of tertiary epilepsy center in Umbria, Italy...
November 8, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29125033/medical-costs-in-patients-with-heart-failure-after-acute-heart-failure-events-one-year-follow-up-study
#12
Eugene Kim, Hye-Young Kwon, Sang Hong Baek, Haeyoung Lee, Byung-Su Yoo, Seok-Min Kang, Youngkeun Ahn, Bongmin Yang
AIMS: This study investigated annual medical costs using real-world data focusing on acute heart failure. METHODS: The data were retrospectively collected from 6 tertiary hospitals in South Korea. Overall, about 330 patients who were hospitalized for acute heart failure between January 2011 and July 2012 were selected. We collected data on their follow-up medical visits for one year, including medical costs incurred toward treatment. Those who died within the observational period or who had no records of follow-up visits were excluded...
November 10, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29121961/a-multicomponent-intervention-for-the-management-of-chronic-pain-in-older-adults-study-protocol-for-a-randomized-controlled-trial
#13
Sheung-Tak Cheng, Ka Long Chan, Rosanna W L Lam, Monique H T Mok, Phoon Ping Chen, Yu Fat Chow, Joanne W Y Chung, Alexander C B Law, Jenny S W Lee, Edward M F Leung, Cindy W C Tam
BACKGROUND: Studies have shown that physical interventions and psychological methods based on the cognitive behavioral approach are efficacious in alleviating pain and that combining both tends to yield more benefits than either intervention alone. In view of the aging population with chronic pain and the lack of evidence-based pain management programs locally, we developed a multicomponent intervention incorporating physical exercise and cognitive behavioral techniques and examined its long-term effects against treatment as usual (i...
November 9, 2017: Trials
https://www.readbyqxmd.com/read/29111136/factors-associated-with-response-to-biofeedback-therapy-for-dyssynergic-defecation
#14
Tanisa Patcharatrakul, Jessica Valestin, Amanda Schmeltz, Konrad Schulze, Satish S C Rao
BACKGROUND & AIMS: Biofeedback therapy (BT) is effective for dyssynergic defecation (DD), but it is not widely available or reimbursed, and is labor intensive. It is therefore important to select the appropriate patients for this treatment. We investigated symptoms and demographic, manometric, and other factors associated with outcomes of BT in patients with DD. METHODS: We performed a post-hoc analysis of 2 prospective studies of BT in 127 adult outpatients (18-75 years old, 120 female) with chronic constipation who failed to respond to treatment with dietary fiber or laxatives (>1 year) and were diagnosed with DD based on standard criteria...
October 27, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29105991/hypertension-and-frailty-in-older-adults
#15
Ivan Aprahamian, Eduardo Sassaki, Marília F Dos Santos, Rafael Izbicki, Rafael C Pulgrossi, Marina M Biella, Ana Camila N Borges, Marcela M Sassaki, Leonardo M Torres, Ícaro S Fernandez, Olívia A Pião, Paula L M Castro, Pedro A Fontenele, Mônica S Yassuda
The association between hypertension and frailty syndrome in older adults remains unclear. There is scarce information about the prevalence of hypertension among frail elderly patients or on its relationship with frailty. Up to one quarter of frail elderly patients present without comorbidity or disability, yet frailty is a leading cause of death. The knowledge and better control of frailty risk factors could influence prognosis. The present study evaluated: (1) the prevalence of hypertension in robust, prefrail, and frail elderly; and (2) factors that might be associated with frailty including hypertension...
November 5, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29105971/home-based-tactile-discrimination-training-tdt-reduces-phantom-limb-pain
#16
Robert Wakolbinger, Martin Diers, Laura A Hruby, Agnes Sturma, Oskar C Aszmann
BACKGROUND: Phantom limb pain (PLP) affects a high percentage of amputees. Since treatment options are limited, low quality of life and addiction to pain medication is frequent. New attempts, such as mirror therapy or electrical sensory discrimination training, make use of the brain's plasticity to alleviate this centrally derived pain. AIM: This pilot study assessed the question, whether home-based tactile discrimination training (TDT) leads to a stronger decrease in phantom limb pain levels, compared to a standard massage treatment...
November 6, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29105824/wound-culture-isolated-antibiograms-and-caregiver-reported-skin-care-practices-in-children-with-epidermolysis-bullosa
#17
Hannah M Singer, Laura E Levin, Maria C Garzon, Christine T Lauren, Paul J Planet, Nicole W Kittler, Susan Whittier, Kimberly D Morel
BACKGROUND/OBJECTIVES: Many patients with epidermolysis bullosa (EB) require intensive daily wound care and individualized treatment plans. Understanding patient's home skin care routines and emerging antibiotic resistance patterns in EB wounds is necessary to optimize treatment recommendations. The objective was to identify patterns of antimicrobial resistance in EB wounds and characterize patient's home practices of skin care and bathing. METHODS: This was an observational study of 23 children with EB at an outpatient pediatric dermatology practice in New York City from 2012 to 2014...
November 6, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29105515/implementation-and-evaluation-of-the-norwegian-ullevaal-model-as-a-cardiac-rehabilitation-model-in-primary-care
#18
Birgitta Blakstad Nilsson, Pernille Lunde, Inger Holm
PURPOSE: To describe the Norwegian Ullevaal model, customised for cardiac patients in primary care, and to evaluate the feasibility of the model through patient outcomes after the 12 week outpatient cardiac rehabilitation programme. MATERIALS AND METHODS: A descriptive interventional cohort study with pre-post design. Patients referred to cardiac rehabilitation (n = 273) were enrolled. Group-based high-intensity interval training was offered twice weekly. The primary outcome measure was change in peak oxygen uptake...
November 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29103050/motivators-and-barriers-to-exercise-in-parkinson-s-disease
#19
Mitra Afshari, Amy Yang, Danny Bega
BACKGROUND: Despite evidence for the benefits of exercise in Parkinson's disease (PD), many patients remain sedentary for undefined reasons. OBJECTIVE: To compare exercise habits, perceptions about exercise, and barriers to exercise in 'low' (<3 h/week) and 'high' (≥3 h/week) exercisers with PD. METHODS: A 48-item survey was administered to PD patients at an outpatient academic center. Chi-squared tests were used to compare the percentage differences between low- and high-exercisers with two-sided tests and a significant level of 0...
2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/29102985/study-protocol-for-a-randomised-controlled-trial-of-ultrasound-guided-pulsed-radiofrequency-of-the-genicular-nerves-in-the-treatment-of-patients-with-osteoarthritis-knee-pain
#20
Javier Mata, Pedro Valentí, Beatriz Hernández, Bartolome Mir, Jose Luis Aguilar
INTRODUCTION: The goals for the management of patients with osteoarthritis (OA) of the knee are to control pain and to minimise disability. Because the number of patients will increase as the population ages, alternative approaches to alleviate their joint pain other than conventional treatments are necessary. The purpose of this article is to present a refined protocol to determine if there is long-term improvement in pain and function after ultrasound-guided pulsed radiofrequency treatment of the genicular nerves (GNs) in patients with chronic painful knee OA...
November 3, 2017: BMJ Open
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