keyword
MENU ▼
Read by QxMD icon Read
search

Market research

keyword
https://www.readbyqxmd.com/read/28526330/going-social-success-in-online-recruitment-of-men-who-have-sex-with-men-for-prevention-hiv-vaccine-research
#1
Lindsey Buckingham, Julie Becher, Chelsea D Voytek, Danielle Fiore, Debora Dunbar, Annet Davis-Vogel, David S Metzger, Ian Frank
OBJECTIVE: To compare the use of four different social media sites to recruit men who have sex with men (MSM) and transgender women to a phase 2b HIV prevention vaccine trial, HVTN 505. DESIGN: Retrospective, observational study. METHODS: The University of Pennsylvania HIV Vaccine Trials Unit (Penn HVTU) employed street outreach and online recruitment methods to recruit participants for HVTN 505 using a combination of national recruitment images/messages with Philadelphia-specific language and imagery...
May 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28523384/the-need-for-restructuring-the-disordered-science-of-amorphous-drug-formulations
#2
REVIEW
Khadijah Edueng, Denny Mahlin, Christel A S Bergström
The alarming numbers of poorly soluble discovery compounds have centered the efforts towards finding strategies to improve the solubility. One of the attractive approaches to enhance solubility is via amorphization despite the stability issue associated with it. Although the number of amorphous-based research reports has increased tremendously after year 2000, little is known on the current research practice in designing amorphous formulation and how it has changed after the concept of solid dispersion was first introduced decades ago...
May 18, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28522405/challenges-and-opportunities-for-the-development-of-new-antipsychotic-drugs
#3
REVIEW
Carlos Forray, Raimund Buller
In spite of the significant impact that the serendipitous discovery of drugs with antipsychotic properties had on the care of patients with psychotic disorders, there are significant challenges when aiming at therapeutic goals such as remission, recovery, improved health-related quality of life and functioning. The efficacy and effectiveness of existing antipsychotic drugs fail to address the full spectrum of symptoms and functional deficits that currently prevent patients with psychotic disorders from achieving fulfilling lives...
May 15, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28522099/psychometric-properties-and-dutch-norm-values-of-the-children-s-sleep-habits-questionnaire-in-toddlers
#4
Lindsay Martina Helena Steur, Eva Henriëtte Visser, Martha Alexandra Grootenhuis, Caroline Barbara Terwee, Gerardus Johannes Laurentius Kaspers, Raphaële Reine Lydie van Litsenburg
OBJECTIVE: The Children's Sleep Habits Questionnaire (CSHQ) was developed in the USA for children aged 4-10 years. The Dutch CSHQ has been validated for this age group, but not yet for toddlers. Furthermore, Dutch norm values for toddlers are unavailable. This study aimed to investigate the psychometric properties and collect norm values of the Dutch CSHQ in toddlers. METHODS: Data collection was conducted by Taylor Nelson Sofres Netherlands Institute for Public Opinion (TNS-NIPO), a Dutch market research agency...
June 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28521696/nanotechnology-as-a-promising-strategy-for-anticancer-drug-delivery
#5
Mona Basha
Cancer was and still a very stressful and urgent disease condition representing a leading cause of death in developed as well as developing countries. Although, much research work in both medical and pharmaceutical fields has evolved in the past few years in addition to some promising clinical trials and few market products, cancer becomes much wilder, threatening and getting more lives. Most approaches have focused on the synthesis of new active ingredients or chemical modification of available ones, formulating them in suitable dosage forms aiming for targeted and effective drug delivery with minimal side effects...
May 15, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/28521373/paediatric-medicines-regulatory-and-scientific-issues
#6
Chrysa Daousani, Vangelis D Karalis
In the past, dosage regimens authorized for adults were extrapolated to children relying mainly on empirical dosage adjustments. However, children are not small adults, but a distinct and heterogeneous group in terms of physiology, disease occurrence, pharmacokinetics, pharmacodynamics and also psychological, cognitive, and behavioral aspects. Even though it would be helpful to know the physiological changes and the special drug treatment needs in children, this task could not be performed due to ethical reasons...
May 18, 2017: Drug Research
https://www.readbyqxmd.com/read/28515189/10-year-trends-in-statin-utilization-in-taiwan-a-retrospective-study-using-taiwan-s-national-health-insurance-research-database
#7
Hsing-Chun Hsieh, Jason C Hsu, Christine Y Lu
OBJECTIVE: Statins have been commonly used to treat patients with hypercholesterolaemia and to prevent cardiovascular disease (CVD) worldwide. This study examined trends in use of statins in Taiwan from 2002 to 2011. DESIGN: This is a retrospective observational study focusing on the utilisation of statins. SETTING: The monthly claims data for statins between 2002 and 2011 were retrieved from Taiwan's National Health Insurance Research Database...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28514702/nanoscale-morphological-analysis-of-soft-matter-aggregates-with-fractal-dimension-ranging-from-1-to-3
#8
REVIEW
Francesco Valle, Marco Brucale, Stefano Chiodini, Eva Bystrenova, Cristiano Albonetti
While the widespread emergence of nanoscience and nanotechnology can be dated back to the early eighties, the last decade has witnessed a true coming of age of this research field, with novel nanomaterials constantly finding their way into marketed products. The performance of nanomaterials being dominated by their nanoscale morphology, their quantitative characterization with respect to a number of properties is often crucial. In this context, those imaging techniques able to resolve nanometer scale details are clearly key players...
May 4, 2017: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/28513099/syntheses-analytical-and-pharmacological-characterizations-of-the-legal-high-4-1-3-methoxyphenyl-cyclohexyl-morpholine-3-meo-pcmo-and-analogues
#9
Tristan Colestock, Jason Wallach, Matt Mansi, Nadine Filemban, Hamilton Morris, Simon P Elliott, Folker Westphal, Simon D Brandt, Adeboye Adejare
New psychoactive substances (NPS) are commonly referred to as "research chemicals", "designer drugs" or "legal highs." One NPS class is represented by dissociative anesthetics, which include analogues of the arylcyclohexylamine phencyclidine (PCP), ketamine, and diphenidine. A recent addition to the NPS market was 4-[1-(3-methoxyphenyl)cyclohexyl]morpholine (3-MeO-PCMo), a morpholine analogue of 3-MeO-PCP. Although suspected to have dissociative effects in users, information about its pharmacological profile is not available...
May 16, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28511551/theoretical-foundations-of-appeals-used-in-alcohol-abuse-and-drunk-driving-public-service-announcements-in-the-united-states-1995-2010
#10
Jeff Niederdeppe, Rosemary J Avery, Emily Elizabeth Namaste Miller
PURPOSE: The study identifies the extent to which theoretical constructs drawn from well-established message effect communication theories are reflected in the content of alcohol-related public service announcements (PSAs) airing in the United States over a 16-year period. DESIGN: Content analysis of 18 530 141 alcohol-abuse (AA) and drunk-driving (DD) PSAs appearing on national network and local cable television stations in the 210 largest designated marketing areas (DMAs) from January 1995 through December 2010...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28510497/clinical-development-and-commercialization-of-advanced-therapy-medicinal-products-atmps-in-the-eu-how-are-the-product-pipeline-and-regulatory-framework-evolving
#11
Tomáš Boráň, Margarida Menezes-Ferreira, Ilona Reischl, Patrick Celis, Nicolas Ferry, Bernd Gänsbacher, Hartmut Krafft, Michele Lipucci Di Paola, Dariusz Sladowski, Paula Salmikangas
The research and development of Advanced Therapy Medicinal Products (ATMPs) has been active in Europe and worldwide during recent years, yet the number of licensed products remains still low. The main expected legal change in near future in the EU concerns the regulation on clinical trials (536/2014), which will come into force in 2018. With this new framework a more harmonized and swift process for approval of clinical trials is awaited, which is expected to support the entry of new innovations into the EU market...
May 16, 2017: Human Gene Therapy. Clinical Development
https://www.readbyqxmd.com/read/28509518/the-dental-public-health-implications-of-cosmetic-dentistry-a-scoping-review-of-the-literature
#12
J Doughty, R Lala, Z Marshman
INTRODUCTION: The popularity of cosmetic surgery has seen a rapid increase recently, with the trend mirrored in dentistry. The Department of Health expressed concerns about the potential for biological and psychosocial harm of these cosmetic procedures. Furthermore, the dental public health implications (DPH) of the growing uptake of cosmetic dental procedures have not been explored. OBJECTIVES: Conduct a scoping review to explore the DPH implications of cosmetic dentistry and identify gaps for future research...
September 2016: Community Dental Health
https://www.readbyqxmd.com/read/28509503/-own-label-versus-branded-commercial-dental-resin-composite-materials-mechanical-and-physical-property-comparisons
#13
Kathryn Shaw, Ricardo Martins, Mohammed Abdul Hadis, Trevor Burke, William Palin
A majority of dental materials are manufactured by companies who have experience in the field. However, a number of "own label" materials have become available, principally marketed by distributors and other companies with little or no experience in the field. These materials are attractive because of their reduced cost, but they may have no research on which clinicians might base their potential performance. It is therefore the purpose of this work to compare the performance of different batches of a number of "own-label" dental materials with a similar number from manufacturers with experience in the field, using a variety of laboratory test regimes which include filler determination, degree of conversion, flexural strength and flexural modulus, in order to evaluate key material properties...
September 2016: European Journal of Prosthodontics and Restorative Dentistry
https://www.readbyqxmd.com/read/28508807/new-service-excellence-model-for-ehealth-and-aal-solutions-a-framework-for-continuous-new-service-development
#14
Johannes Kriegel, Luise Reckwitz, Klemens Auinger, Linda Tuttle-Weidinger, Stephanie Schmitt-Rüth, Renate Kränzl-Nagl
The development of eHealth and AAL (Ambient Assisted Living) services with the aim to reduce the complexity of living environments for the elderly often does not lead to the desired results on the market. The design of an eHealth/AAL specific framework for continuous New Service Development is presented in this paper. Our research addresses this challenge with a new Service Excellence Model (SEM) and outlines the benefits of this specific approach. The research is based on the data of the DALIA project (Assistant for DAily LIfe Activities at Home) and the PenAAL project (Performance Measurement Index for AAL solutions), parts of which the projects were the classification of relevant business dimensions and the development of a related scoring tool for continuous benchmarking and improvement...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28508667/professionals-perspectives-on-a-market-inspired-policy-reform-a-guiding-light-to-the-blind-spots-of-measurement
#15
Sara Korlén, Isis Amer-Wåhlin, Peter Lindgren, Ulrica von Thiele Schwarz
Implementation of market-inspired competition and incentive models in health care is increasing worldwide, assumed to drive efficiency. However, the evidence for effects is mixed and unintended consequences have been reported. There is a need to better understand the practical consequences of such reforms. The aim of the present case study is to explore what consequences of a Swedish market-inspired patient choice reform professionals identify as relevant, and why. The study was designed as an explorative qualitative study in specialized orthopedics...
January 1, 2017: Health Services Management Research
https://www.readbyqxmd.com/read/28507427/the-sensimed-triggerfish-contact-lens-sensor-efficacy-safety-and-patient-perspectives
#16
REVIEW
Grace E Dunbar, Bailey Yuguan Shen, Ahmad A Aref
Intraocular pressure, a major modifiable risk factor for glaucoma, has been shown to fluctuate throughout the day in patients with glaucoma. The detection and measurement of this fluctuation may help guide the clinical management of glaucomatous individuals. The Sensimed Triggerfish contact lens sensor (CLS), which has recently gained approval for marketing in the USA, is designed to detect intraocular pressure-related changes in an eye over a 24-hour period. This review will provide an overview of the Triggerfish CLS, as well as summarize current clinical data pertaining to the device...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28507222/meeting-the-goal-of-concurrent-adolescent-and-adult-licensure-of-hiv-prevention-and-treatment-strategies
#17
Michelle Hume, Linda L Lewis, Robert M Nelson
The ability of adolescents to access safe and effective new products for HIV prevention and treatment is optimised by adolescent licensure at the same time these products are approved and marketed for adults. Many adolescent product development programmes for HIV prevention or treatment products may proceed simultaneously with adult phase III development programmes. Appropriately implemented, this strategy is not expected to delay licensure as information regarding product efficacy can often be extrapolated from adults to adolescents, and pharmacokinetic properties of drugs in adolescents are expected to be similar to those in adults...
May 15, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28506868/drug-disease-modeling-in-the-pharmaceutical-industry-where-mechanistic-systems-pharmacology-and-statistical-pharmacometrics-meet
#18
Gabriel Helmlinger, Nidal Al-Huniti, Sergey Aksenov, Kirill Peskov, Melissa Hallow, Lulu Chu, David Boulton, Ulf Eriksson, Bengt Hamrén, Craig Lambert, Eric Masson, Helen Tomkinson, Donald Stanski
Modeling & simulation (M&S) methodologies are established quantitative tools, which have proven to be useful in supporting the research, development (R&D), regulatory approval, and marketing of novel therapeutics. Applications of M&S help design efficient studies and interpret their results in context of all available data and knowledge to enable effective decision-making during the R&D process. In this mini-review, we focus on two sets of modeling approaches: population-based models, which are well-established within the pharmaceutical industry today, and fall under the discipline of clinical pharmacometrics (PMX); and systems dynamics models, which encompass a range of models of (patho-)physiology amenable to pharmacological intervention, of signaling pathways in biology, and of substance distribution in the body (today known as physiologically-based pharmacokinetic models) - which today may be collectively referred to as quantitative systems pharmacology models (QSP)...
May 12, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28506719/two-fatalities-associated-with-synthetic-opioids-ah-7921-and-mt-45
#19
Helena Fels, Julia Krueger, Hans Sachs, Frank Musshoff, Matthias Graw, Gabriele Roider, Andreas Stoever
In this study, two fatalities associated with the synthetic opioids AH-7921 and MT-45 are reported. Within the last few years, both compounds have emerged on the recreational drug market and are sold as "research chemicals" on the internet. In the first case, a 22-year-old woman was found dead in the bedroom of her apartment by two of her friends. A plastic bag labeled "AH-7921" was found in the apartment and the two friends stated that the deceased had consumed AH-7921 prior to her death. The woman was a known drug addict...
April 15, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28506274/contextual-and-psychosocial-factors-predicting-ebola-prevention-behaviours-using-the-ranas-approach-to-behaviour-change-in-guinea-bissau
#20
Anna E Gamma, Jurgita Slekiene, Gregor von Medeazza, Fredrik Asplund, Placido Cardoso, Hans-Joachim Mosler
BACKGROUND: The outbreak of the Ebola virus disease (EVD) in West Africa in December 2013 was the largest Ebola outbreak in history. This study aimed to measure the underlying contextual and psychosocial factors of intentions to perform Ebola prevention behaviours (not touching people who might be suffering from Ebola, reporting suspected cases to the National Ebola Hotline, NEH) in Guinea-Bissau. Geographical location, cross-border market activities, poor water, sanitation and hygiene (WASH) conditions, and burial practices in some communities pose a serious risk in terms of potential EVD outbreak and seriously hamper its prevention in Guinea-Bissau...
May 15, 2017: BMC Public Health
keyword
keyword
119125
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"