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Mariet research

Mariet Allen, Minerva M Carrasquillo, Cory Funk, Benjamin D Heavner, Fanggeng Zou, Curtis S Younkin, Jeremy D Burgess, High-Seng Chai, Julia Crook, James A Eddy, Hongdong Li, Ben Logsdon, Mette A Peters, Kristen K Dang, Xue Wang, Daniel Serie, Chen Wang, Thuy Nguyen, Sarah Lincoln, Kimberly Malphrus, Gina Bisceglio, Ma Li, Todd E Golde, Lara M Mangravite, Yan Asmann, Nathan D Price, Ronald C Petersen, Neill R Graff-Radford, Dennis W Dickson, Steven G Younkin, Nilüfer Ertekin-Taner
Previous genome-wide association studies (GWAS), conducted by our group and others, have identified loci that harbor risk variants for neurodegenerative diseases, including Alzheimer's disease (AD). Human disease variants are enriched for polymorphisms that affect gene expression, including some that are known to associate with expression changes in the brain. Postulating that many variants confer risk to neurodegenerative disease via transcriptional regulatory mechanisms, we have analyzed gene expression levels in the brain tissue of subjects with AD and related diseases...
October 11, 2016: Scientific Data
Brooke Levis, Danielle B Rice, Linda Kwakkenbos, Russell J Steele, Mariët Hagedoorn, Marie Hudson, Murray Baron, Brett D Thombs
OBJECTIVE: Married persons have, on average, better mental health than nonmarried persons. Among married persons, marital satisfaction is associated with better mental health. Studies on mental health in married and nonmarried persons that consider marital satisfaction have categorized patients as satisfied versus unsatisfied, which reduces statistical power and does not generate clinically useful information on mental health across the satisfaction spectrum. Our objective was to demonstrate a novel regression approach to evaluate mental health in women with systemic sclerosis (SSc), comparing married and unmarried women, accounting for continuously measured marital satisfaction...
August 2016: Arthritis Care & Research
Martin A Benjamin, Garrett Schwarzman, Mariet Eivazi, Lawrence Zachary
Autologous fat tissue transfer for aesthetic reconstruction has been described in the literature for soft tissue damage as early as 1893. One area that has yet to be described is the role of fat grafting in post-traumatic lower extremity injuries. In this case report, we present a patient who had significant injury to her right lower extremity and presented for reconstruction. The patient is a 52-year-old female who presented to clinic after a right lower extremity traumatic injury that required multiple re-operations, which lead to dense scarring and volume loss along the extremity inferior to the knee joint...
2015: Journal of Surgical Case Reports
Els van der Meijden, Siamaque Kazem, Christina A Dargel, Nick van Vuren, Paul J Hensbergen, Mariet C W Feltkamp
UNLABELLED: The polyomavirus tumor (T) antigens play crucial roles in viral replication, transcription, and cellular transformation. They are encoded by partially overlapping open reading frames (ORFs) located in the early region through alternative mRNA splicing. The T expression pattern of the trichodysplasia spinulosa-associated polyomavirus (TSPyV) has not been established yet, hampering further study of its pathogenic mechanisms and taxonomic relationship. Here, we characterized TSPyV T antigen expression in human cell lines transfected with the TSPyV early region...
September 2015: Journal of Virology
Vicky Lehmann, Mariët Hagedoorn, Cynthia A Gerhardt, Marci Fults, Randal S Olshefski, Robbert Sanderman, Marrit A Tuinman
OBJECTIVE: Research on body image and sexual satisfaction after adult onset cancer has shown significant and lasting impairments regarding survivors' sexuality and romantic relationships. However, knowledge about these topics and their associations in adult survivors of childhood cancer is largely lacking. METHODS: Participants completed web-based questionnaires concerning body image, body dissociation, sexual satisfaction, and relationship status satisfaction (i...
February 2016: Psycho-oncology
Mariët J van der Werf, Ralf Takors, Jørn Smedsgaard, Jens Nielsen, Tom Ferenci, Jean Charles Portais, Christoph Wittmann, Mark Hooks, Alberta Tomassini, Marco Oldiges, Jennifer Fostel, Uwe Sauer
With the increasing use of metabolomics as a means to study a large number of different biological research questions, there is a need for a minimal set of reporting standards that allow the scientific community to evaluate, understand, repeat, compare and re-investigate metabolomics studies. Here we propose, a first draft of minimal requirements to effectively describe the biological context of metabolomics studies that involve microbial or in vitro biological subjects. This recommendation has been produced by the microbiology and in vitro biology working subgroup of the Metabolomics Standards Initiative in collaboration with the yeast systems biology network as part of a wider standardization initiative led by the Metabolomics Society...
2007: Metabolomics: Official Journal of the Metabolomic Society
Helene Terp, Nina Rottmann, Pia Veldt Larsen, Mariët Hagedoorn, Henrik Flyger, Niels Kroman, Christoffer Johansen, Susanne Dalton, Dorte Gilså Hansen
OBJECTIVE: Participation bias may be a problem in couple-based psychosocial studies. Therefore, it is important to investigate the characteristics associated with participation. The aim of this study was to analyze whether participation in a longitudinal psychosocial questionnaire study among couples affected by breast cancer was associated with socioeconomic, breast cancer-specific, and other health-related characteristics of the patients and partners. METHODS: The analyzes are based on 2254 couples who were invited to participate in a nationwide survey on psychosocial adjustment among couples dealing with breast cancer...
July 2015: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Dounya Schoormans, Mirjam A G Sprangers, Joost P van Melle, Petronella G Pieper, Arie P J van Dijk, Gertjan T J Sieswerda, Mariët S Hulsbergen-Zwarts, Thijs Hwm Plokker, Leo G H Brunninkhuis, Hubert W Vliegen, Barbara J M Mulder
BACKGROUND: To deliver adequate care to patients with congenital heart disease (CHD), it is important to know which patients use what type of care. This knowledge is valuable, as modification of these factors may be used as means to regulate healthcare use. Our objective was to examine the predictive value of psychological characteristics for future healthcare use, independent of clinical characteristics. METHODS: In total 845 adult CHD-patients participated in a longitudinal questionnaire study, with a two-year follow-up period...
February 2016: European Journal of Cardiovascular Nursing
Kirsten C Smeets, Anouk A M Leeijen, Mariët J van der Molen, Floor E Scheepers, Jan K Buitelaar, Nanda N J Rommelse
Maladaptive aggression in adolescents is an increasing public health concern. Cognitive Behavior Therapy (CBT) is one of the most common and promising treatments of aggression. However, there is a lack of information on predictors of treatment response regarding CBT. Therefore, a meta-analysis was performed examining the role of predictors on treatment response of CBT. Twenty-five studies were evaluated (including 2,302 participants; 1,580 boys and 722 girls), and retrieved through searches on PubMed, PsycINFO and EMBASE...
March 2015: European Child & Adolescent Psychiatry
Mariët Hagedoorn, Franziska L Hein, Torben Schulz, Jaap J Homan van der Heide, Jan Niesing, Ralf Westerhuis, Rutger J Ploeg, Adelita V Ranchor
BACKGROUND: Recruitment of participants for studies focusing on couples facing illness is a challenging task and participation decline may be associated with nonrandom factors creating bias. This study examines whether patient and relationship characteristics are associated with partner participation in research. METHOD: Patients invited to participate in a cross-sectional study on adaptation and quality of life after renal transplantation were asked to forward information about an add-on study to their partners...
March 2015: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
Elise J Kenter, Winifred A Gebhardt, Irene Lottman, Mariët van Rossum, Margreet Bekedam, Mathilde R Crone
OBJECTIVE: Physical activity (PA) can improve well-being and health during older age. This study explored how life events influence PA patterns of older adults. DESIGN: Seventeen interviews with older adults were conducted using a life history method. PA patterns during the life course were identified, including information on when, how and why changes in PA occurred. RESULTS: Four different response patterns that affect PA patterns after life events (e...
2015: Psychology & Health
Vicky Lehmann, Helena Grönqvist, Gunn Engvall, Malin Ander, Marrit A Tuinman, Mariët Hagedoorn, Robbert Sanderman, Elisabet Mattsson, Louise von Essen
OBJECTIVE: The aim of this study was to provide insight into survivor-reported negative and positive consequences of cancer during adolescence 10 years after diagnosis and compare these with consequences reported 3 and 4 years after diagnosis. METHODS: Three, 4, and 10 years after diagnosis, survivors of adolescent cancer were interviewed about negative and positive consequences due to their cancer experience. Manifest content analysis was used to identify categories of reported consequences...
November 2014: Psycho-oncology
Chris Hinnen, Grieteke Pool, Nynke Holwerda, Mirjam Sprangers, Robbert Sanderman, Mariet Hagedoorn
OBJECTIVE: In the present study, we investigated individual differences in the outcome of patient-physician trust when confronted with cancer from an attachment theoretical perspective. We expected that lower levels of trust are associated with more emotional distress and more physical limitations within the first 15 months after diagnosis, especially in those who score relatively high on attachment anxiety. No such association was expected for more avoidantly attached individuals. METHOD: A group of 119 patients with different types of cancer (breast, cervical, intestinal and prostate) completed questionnaires concerning trust (short version of the Wake Forest Physician Trust Scale) and attachment (Experiences in Close Relationship scale Revised) at 3 months after diagnosis...
July 2014: General Hospital Psychiatry
Wouter J Kikkert, Nan van Geloven, Mariet H van der Laan, Marije M Vis, Jan Baan, Karel T Koch, Ron J Peters, Robbert J de Winter, Jan J Piek, Jan G P Tijssen, José P S Henriques
OBJECTIVES: The aim of the present analysis was to compare 1-year mortality prediction of Bleeding Academic Research Consortium (BARC)-defined bleeding complications with existing bleeding definitions in patients with ST-segment elevation myocardial infarction (STEMI) and to investigate the prognostic value of the individual data elements of the bleeding classifications for 1-year mortality. BACKGROUND: BARC recently proposed a novel standardized bleeding definition...
May 13, 2014: Journal of the American College of Cardiology
Francesca Romito, Gil Goldzweig, Claudia Cormio, Mariët Hagedoorn, Barbara L Andersen
According to the recent worldwide estimation by the GLOBOCAN project, in total, 12.7 million new cancer cases and 7.6 million cancer deaths occurred in 2008. The worldwide number of cancer survivors within 5 years of diagnosis has been estimated at be almost 28.8 million. Informal caregivers, such as family members and close friends, provide essential support to cancer patients. The authors of this report provide an overview of issues in the study of informal caregivers for cancer patients and long-term survivors in the United States and Europe, characterizing the caregivers commonly studied; the resources currently available to them; and their unmet needs, their psychosocial outcomes, and the psychosocial interventions tailored to their special circumstances...
June 1, 2013: Cancer
Johannes H C Cornelissen, Ute Sass-Klaassen, Lourens Poorter, Koert van Geffen, Richard S P van Logtestijn, Jurgen van Hal, Leo Goudzwaard, Frank J Sterck, René K W M Klaassen, Grégoire T Freschet, Annemieke van der Wal, Henk Eshuis, Juan Zuo, Wietse de Boer, Teun Lamers, Monique Weemstra, Vincent Cretin, Rozan Martin, Jan den Ouden, Matty P Berg, Rien Aerts, Godefridus M J Mohren, Mariet M Hefting
Dead wood provides a huge terrestrial carbon stock and a habitat to wide-ranging organisms during its decay. Our brief review highlights that, in order to understand environmental change impacts on these functions, we need to quantify the contributions of different interacting biotic and abiotic drivers to wood decomposition. LOGLIFE is a new long-term 'common-garden' experiment to disentangle the effects of species' wood traits and site-related environmental drivers on wood decomposition dynamics and its associated diversity of microbial and invertebrate communities...
2012: Ambio
Torben Schulz, Jan Niesing, Roy E Stewart, Ralf Westerhuis, Mariet Hagedoorn, Rutger J Ploeg, Jaap J Homan van der Heide, Adelita V Ranchor
Although kidney transplantation improves overall quality of life and physical functioning, improvements of psychological distress are often modest. However, apparent stressors such as comorbidity are only weakly associated with psychological distress and their impact differs considerably between patients. Wilson and Cleary proposed a theoretical model to explain these relationships. This model has been supported by research, but has never been applied in a population of kidney transplant recipients. Findings of the current study are based on a cross-sectional study carried out in 2008 in the northern Netherlands...
October 2012: Social Science & Medicine
Amber Ronteltap, Siet J Sijtsema, Hans Dagevos, Mariët A de Winter
Although many studies consider health and food, little is known about consumers' actual interpretation of healthy eating. This study aims to explore, operationalise, and test consumers' interpretation of healthy eating by using insights from construal level theory. In this exploratory research three consecutive studies were executed, applying focus group (n=35) and two quasi-experimental studies with, respectively 97 and 235 respondents. Respondents appeared to use different levels for their judgment of food products' healthiness...
October 2012: Appetite
Mirjam van Veen, Ewout W Steyerberg, Mariët Van't Klooster, Madelon Ruige, Alfred H J van Meurs, Johan van der Lei, Henriëtte A Moll
OBJECTIVE: To improve the Manchester Triage System (MTS) in paediatric emergency care. METHODS: The authors performed a prospective observational study at the emergency departments of a university and teaching hospital in The Netherlands and included children attending in 2007 and 2008. The authors developed and implemented specific age-dependent modifications for the MTS, based on patient groups where the system's performance was low. Nurses applied the modified system in 11,481 (84%) patients...
August 2012: Emergency Medicine Journal: EMJ
James C Coyne, Brett D Thombs, Mariet Hagedoorn
OBJECTIVE: We examined four meta-analyses of behavioral interventions for adults (Dixon, Keefe, Scipio, Perri, & Abernethy, 2007; Hoffman, Papas, Chatkoff, & Kerns, 2007; Irwin, Cole, & Nicassio, 2006; and Jacobsen, Donovan, Vadaparampil, & Small, 2007) that have appeared in the Evidence Based Treatment Reviews section of Health Psychology. DESIGN: Narrative review. MAIN OUTCOME MEASURES: We applied the following criteria to each meta-analysis: (1) whether each meta-analysis was described accurately, adequately, and transparently in the article; (2) whether there was an adequate attempt to deal with methodological quality of the original trials; (3) the extent to which the meta-analysis depended on small, underpowered studies; and (4) the extent to which the meta-analysis provided valid and useful evidence-based recommendations...
March 2010: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
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