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https://www.readbyqxmd.com/read/28549480/improving-the-appropriateness-of-antipsychotic-prescribing-in-nursing-homes-a-mixed-methods-process-evaluation-of-an-academic-detailing-intervention
#1
L Desveaux, M Saragosa, J Rogers, L Bevan, H Loshak, A Moser, S Feldman, L Regier, L Jeffs, N M Ivers
BACKGROUND: In 2014, nursing home administration and government officials were facing increasing public and media scrutiny around the variation of antipsychotic medication (APM) prescribing across Ontario nursing homes. In response, policy makers partnered to test an academic detailing (AD) intervention to address appropriate prescribing of APM in nursing homes in a cluster-randomized trial. This mixed-methods study aimed to explore how and why the AD intervention may have resulted in changes in the nursing home context...
May 26, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28538762/papillary-muscle-free-strain-in-patients-with-severe-degenerative-and-functional-mitral-regurgitation
#2
Alev Kılıcgedik, Gokhan Kahveci, Ahmet Seyfeddin Gurbuz, Can Yucel Karabay, Ahmet Guler, Suleyman Cagan Efe, Soe Moe Aung, Ugur Arslantas, Serdar Demir, Ibrahim Akin Izgi, Cevat Kirma
Fundamento: The role of papillary muscle function in severe mitral regurgitation with preserved and reduced left ventricular ejection fraction and the method of choice to evaluate PM have still been the subjects of controversy. Objectives: To evaluate and compare papillary muscle function in and between patients with severe degenerative and functional mitral regurgitation by using the free strain method. Methods: 64 patients with severe mitral regurgitation - 39 patients with degenerative mitral regurgitation (DMR group) and 25 patients with severe functional mitral regurgitation (FMR group) - and 30 control subjects (control group) were included in the study...
April 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28536458/epigenetic-priming-restores-the-hla-class-i-antigen-processing-machinery-expression-in-merkel-cell-carcinoma
#3
Cathrin Ritter, Kaiji Fan, Annette Paschen, Sine Reker Hardrup, Soldano Ferrone, Paul Nghiem, Selma Ugurel, David Schrama, Jürgen C Becker
Merkel cell carcinoma (MCC) is a rare and aggressive, yet highly immunogenic skin cancer. The latter is due to its viral or UV-associated carcinogenesis. For tumor progression MCC has to escape the host's immuno-surveillance, e.g. by loss of HLA class-I expression. Indeed, a reduced HLA class-I expression was observed in MCC tumor tissues and MCC cell lines. This reduced HLA class-I surface expression is caused by an impaired expression of key components of the antigen processing machinery (APM), including LMP2 and LMP7 as well as TAP1 and TAP2...
May 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28522452/arthroscopic-partial-meniscectomy-versus-placebo-surgery-for-a-degenerative-meniscus-tear-a-2-year-follow-up-of-the-randomised-controlled-trial
#4
Raine Sihvonen, Mika Paavola, Antti Malmivaara, Ari Itälä, Antti Joukainen, Heikki Nurmi, Juha Kalske, Anna Ikonen, Timo Järvelä, Tero Ah Järvinen, Kari Kanto, Janne Karhunen, Jani Knifsund, Heikki Kröger, Tommi Kääriäinen, Janne Lehtinen, Jukka Nyrhinen, Juha Paloneva, Outi Päiväniemi, Marko Raivio, Janne Sahlman, Roope Sarvilinna, Sikri Tukiainen, Ville-Valtteri Välimäki, Ville Äärimaa, Pirjo Toivonen, Teppo Ln Järvinen
OBJECTIVE: To assess if arthroscopic partial meniscectomy (APM) is superior to placebo surgery in the treatment of patients with degenerative tear of the medial meniscus. METHODS: In this multicentre, randomised, participant-blinded and outcome assessor-blinded, placebo-surgery controlled trial, 146 adults, aged 35-65 years, with knee symptoms consistent with degenerative medial meniscus tear and no knee osteoarthritis were randomised to APM or placebo surgery. The primary outcome was the between-group difference in the change from baseline in the Western Ontario Meniscal Evaluation Tool (WOMET) and Lysholm knee scores and knee pain after exercise at 24 months after surgery...
May 18, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28489716/the-medicare-access-and-chip-reauthorization-act-macra-of-2015-what-s-new
#5
Zain Sayeed, Mouhanad El-Othmani, William O Shaffer, Khaled J Saleh
The Centers for Medicare and Medicaid Services (CMS) released its Final Rule on the Medicare Access and CHIP [Children's Health Insurance Program] Reauthorization Act (MACRA) in November 2016. The Rule finalizes the details of the merit-based incentive payment system (MIPS) and the alternative payment model (APM), which will now collectively be referred to as the Quality Payment Program (QPP). This article offers the orthopaedic community a summary of the alterations in healthcare policy that will affect practices nationwide...
June 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28449827/meeting-its-mission-does-psychosomatics-align-with-the-mission-of-its-parent-organization-the-academy-of-psychosomatic-medicine
#6
John B Taylor, Theodore A Stern
BACKGROUND: The vision and mission statements of the Academy of Psychosomatic Medicine (APM) indicate that the APM should promote excellence in clinical care for patients with comorbid psychiatric and general medical conditions by seeking to influence research, public policy, and interdisciplinary education. OBJECTIVE: As the APM owns the journal, Psychosomatics, we sought to assess whether the APM's journal was fulfilling the vision and mission of its parent organization by reviewing the content of articles published in the journal to determine whether it sufficiently addresses the various clinical care knowledge areas it seeks to influence...
March 8, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28446388/medial-shoe-ground-pressure-and-specific-running-injuries-a-1-year-prospective-cohort-study
#7
René B K Brund, Sten Rasmussen, Rasmus O Nielsen, Uwe G Kersting, Uffe Laessoe, Michael Voigt
OBJECTIVES: Achilles tendinitis, plantar fasciopathy and medial tibial stress syndrome injuries (APM-injuries) account for approximately 25% of the total number of running injuries amongst recreational runners. Reports on the association between static foot pronation and APM-injuries are contradictory. Possibly, dynamic measures of pronation may display a stronger relationship with the risk of APM-injuries. Therefore, the purpose of the present study was to investigate if running distance until the first APM-injury was dependent on the foot balance during stance phase in recreational male runners...
April 15, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28441271/alternative-payment-models-and-urology
#8
Deborah R Kaye, David C Miller, Chad Ellimoottil
PURPOSE OF REVIEW: The Medicare Access and CHIP Reauthorization Act (MACRA) is a historic bill that was recently passed that establishes how quality measurement and practice patterns will affect physician reimbursement. Alternative payment models (APMs) are an essential component of MACRA and Medicare's vision of paying for high-value care. This review describes APMs in the context of MACRA and their impact on urology. RECENT FINDINGS: The majority of urologists will be affected by MACRA...
April 22, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28438503/expanding-role-of-certified-electronic-health-records-technology-in-radiology-the-macra-mandate
#9
Gregory N Nicola, Andrew B Rosenkrantz, Joshua A Hirsch, Ezequiel Silva, Keith J Dreyer, Michael P Recht
Radiology has historically been at the forefront of innovation and the advancement of technology for the benefit of patient care. However, challenges to early implementation prevented most radiologists from adopting and integrating certified electronic health record technology (CEHRT) into their daily workflow despite the early and potential advantages it offered. This circumstance places radiology at a disadvantage in the two payment pathways of the Medicare Access and CHIP Reauthorization Act of 2015: the Merit-Based Incentive Payment System (MIPS) and advanced alternative payment models (APMs)...
April 19, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28438453/effect-of-bundled-payments-and-health-care-reform-as-alternative-payment-models-in-total-joint-arthroplasty-a-clinical-review
#10
REVIEW
Ahmed Siddiqi, Peter B White, Jaydev B Mistry, Chukwuweike U Gwam, James Nace, Michael A Mont, Ronald E Delanois
BACKGROUND: In an effort to control rising healthcare costs, healthcare reforms have developed initiatives to evaluate the efficacy of alternative payment models (APMs) for Medicare reimbursements. The Center for Medicare and Medicaid Services Innovation Center (CMMSIC) introduced the voluntary Bundled Payments for Care Improvement (BPCI) model experiment as a means to curtail Medicare cost by allotting a fixed payment for an episode of care. The purpose of this review is to (1) summarize the preliminary clinical results of the BPCI and (2) discuss how it has led to other healthcare reforms and alternative payment models...
March 20, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28419809/knee-biomechanics-during-jogging-after-arthroscopic-partial-meniscectomy-a-longitudinal-study
#11
Michelle Hall, Tim V Wrigley, Ben R Metcalf, Rana S Hinman, Flavia M Cicuttini, Alasdair R Dempsey, David G Lloyd, Kim L Bennell
BACKGROUND: Altered knee joint biomechanics is thought to play a role in the pathogenesis of knee osteoarthritis and has been reported in patients after arthroscopic partial meniscectomy (APM) while performing various activities. Longitudinally, understanding knee joint biomechanics during jogging may assist future studies to assess the implications of jogging on knee joint health in this population. PURPOSE: To investigate knee joint biomechanics during jogging in patients 3 months after APM and a healthy control group at baseline and 2 years later at follow-up...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28415526/effect-of-variable-aminoalkyl-chains-on-chemical-grafting-of-cellulose-nanofiber-and-their-antimicrobial-activity
#12
Seema Saini, Mohamed Naceur Belgacem, Julien Bras
Recent focus on the preparation of antimicrobial surfaces using cellulose nanofibers (CNF) has gained considerable attention. In this work, functionalization of CNF films in 100% aqueous solution with three different aminosilanes, including 3-aminopropyl trimethoxysilane (APMS), 2-aminoethyl 3-aminopropyl trimethoxysilane (DAMS)and 3-2-(2-aminoethylamino) ethylamino propyl-trimethoxysilane (TAMS) is reported for the fabrication of contact active antimicrobial materials. Grafted CNF films were comprehensively characterized by FTIR, TGA, contact angle, elemental analysis, solid-state (29)Si NMR, FEG-SEM and SEM-EDX...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28414044/the-impact-of-the-medicare-access-and-chip-reauthorization-act-macra-on-the-field-of-ophthalmology
#13
Brenton Kinker, Kaitlyn Dobesh, Nariman Nassiri, Mark S Juzych, M Roy Wilson
PURPOSE: To analyze the impact of the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA) on the field of ophthalmology. DESIGN: A perspective on the effects of MACRA's Quality Payment Program after analysis of the proposed rule, final rule, and commentary submitted by relevant stakeholders. RESULTS: Physicians will need to use one of two payment structures: Merit Based Incentive Payment Systems (MIPS), or Alternative Payment Models (APMs)...
April 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28396098/how-alternative-payment-models-in-emergency-medicine-can-benefit-physicians-payers-and-patients
#14
Nir J Harish, Harold D Miller, Jesse M Pines, Richard D Zane, Jennifer L Wiler
While there has been considerable effort devoted to developing alternative payment models (APMs) for primary care physicians and for episodes of care beginning with inpatient admissions, there has been relatively little attention by payers to developing APMs for specialty ambulatory care, and no efforts to develop APMs that explicitly focus on emergency care. In order to ensure that emergency care is appropriately integrated and valued in future payment models, emergency physicians (EPs) must engage with the stakeholders within the broader health care system...
March 14, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28382915/risk-factors-for-mers-coronavirus-infection-in-dromedary-camels-in-burkina-faso-ethiopia-and-morocco-2015
#15
Eve Miguel, Véronique Chevalier, Gelagay Ayelet, Med Nadir Ben Bencheikh, Hiver Boussini, Daniel Kw Chu, Ikhlass El Berbri, Ouaffa Fassi-Fihri, Bernard Faye, Getnet Fekadu, Vladimir Grosbois, Bryan Cy Ng, Ranawaka Apm Perera, T Y So, Amadou Traore, François Roger, Malik Peiris
Understanding Middle East respiratory syndrome coronavirus (MERS-CoV) transmission in dromedary camels is important, as they consitute a source of zoonotic infection to humans. To identify risk factors for MERS-CoV infection in camels bred in diverse conditions in Burkina Faso, Ethiopia and Morocco, blood samples and nasal swabs were sampled in February-March 2015. A relatively high MERS-CoV RNA rate was detected in Ethiopia (up to 15.7%; 95% confidence interval (CI): 8.2-28.0), followed by Burkina Faso (up to 12...
March 30, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28379516/comparative-leaf-growth-strategies-in-response-to-low-water-and-low-light-availability-variation-in-leaf-physiology-underlies-variation-in-leaf-mass-per-area-in-populus-tremuloides
#16
Alec S Baird, Leander D L Anderegg, Melissa E Lacey, Janneke HilleRisLambers, Elizabeth Van Volkenburgh
Developmental phenotypic plasticity can allow plants to buffer the effects of abiotic and biotic environmental stressors. Therefore, it is vital to improve our understanding of how phenotypic plasticity in ecological functional traits is coordinated with variation in physiological performance in plants. To identify coordinated leaf responses to low-water (LW) versus low-light (LL) availability, we measured leaf mass per area (LMA), leaf anatomical characteristics and leaf gas exchange of juvenile Populus tremuloides Michx...
April 4, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28378585/amine-based-passivating-materials-for-enhanced-optical-properties-and-performance-of-organic-inorganic-perovskites-in-light-emitting-diodes
#17
Seungjin Lee, Jong Hyun Park, Bo Ram Lee, Eui Dae Jung, Jae Choul Yu, Daniele Di Nuzzo, Richard H Friend, Myoung Hoon Song
The use of hybrid organic-inorganic perovskites in optoelectronic applications are attracting an interest because of their outstanding characteristics, which enable a remarkable enhancement of device efficiency. However, solution-processed perovskite crystals unavoidably contain defect sites that cause hysteresis in perovskite solar cells (PeSCs) and blinking in perovskite light-emitting diodes (PeLEDs). Here, we report significant beneficial effects using a new treatment based on amine-based passivating materials (APMs) to passivate the defect sites of methylammonium lead tribromide (MAPbBr3) through coordinate bonding between the nitrogen atoms and undercoordinated lead ions...
April 20, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28365040/future-considerations-for-clinical-dermatology-in-the-setting-of-21st-century-american-policy-reform-the-medicare-access-and-children-s-health-insurance-program-reauthorization-act-and-alternative-payment-models-in-dermatology
#18
John S Barbieri, Jeffrey J Miller, Harrison P Nguyen, Howard P Forman, Jean L Bolognia, Marta J VanBeek
With the introduction of the Medicare Access and Children's Health Insurance Program Reauthorization Act, clinicians who are not eligible for an exemption must choose to participate in 1 of 2 new reimbursement models: the Merit-based Incentive Payment System or Alternative Payment Models (APMs). Although most dermatologists are expected to default into the Merit-based Incentive Payment System, some may have an interest in exploring APMs, which have associated financial incentives. However, for dermatologists interested in the APM pathway, there are currently no options other than joining a qualifying Accountable Care Organization, which make up only a small subset of Accountable Care Organizations overall...
March 30, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28364300/providers-behaviors-and-beliefs-on-prescribing-antipsychotic-medication-to-children-a-qualitative-study
#19
W David Lohr, Kyle B Brothers, Deborah Winders Davis, Carla A Rich, Lesa Ryan, Michael Smith, Michelle Stevenson, Yana Feygin, Charles Woods, John Myers, Gilbert C Liu
Fragmentation in behavioral and mental health care to children has resulted in suboptimal care and high rates of psychotropic medication use, especially antipsychotic medications (APM). A qualitative study, based on the Theory of Planned Behavior (TPB), aimed to better understand prescribing practices, barriers to optimal treatment, and potential interventions to safeguard the use of APM for children in Kentucky. The most common barrier to optimal care was access to mental health specialists. Social norms and pressure from families contribute to increased medication use...
March 31, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28361138/fully-convolutional-neural-network-for-removing-background-in-noisy-images-of-uranium-bearing-particles
#20
Jay G Tarolli, Benjamin E Naes, Lamar Butler, Keeyahna Foster, Caleb M Gumbs, Andrea L Howard, David Willingham
A fully convolutional neural network (FCN) was developed to supersede automatic or manual thresholding algorithms used for tabulating SIMS particle search data. The FCN was designed to perform a binary classification of pixels in each image belonging to a particle or not, thereby effectively removing background signal without manually or automatically determining an intensity threshold. Using 8000 images from 28 different particle screening analyses, the FCN was trained to accurately predict pixels belonging to a particle with near 99% accuracy...
May 2, 2017: Analyst
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