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Multiple sclerosis and exercise

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https://www.readbyqxmd.com/read/29036843/aberrant-peak-lactate-response-in-ms
#1
Kathrin Schlüter, Josephina Maier, Stefan Patra, Stefan M Gold, Christoph Heesen, Karl-Heinz Schulz
BACKGROUND: The peak blood lactate response to an exhaustive exercise test in a number of chronic conditions has been shown to differ from that seen in healthy, untrained individuals. However, this has not been investigated for patients with multiple sclerosis (MS). OBJECTIVE: The main objective was to determine and compare the peak blood lactate response to exercise and the maximal workload between two groups of MS patients with different illness severity. METHODS: Twenty-five patients with a relapsing-remitting disease course (Group RR) and 41 patients with a secondary- or primary chronic progressive disease course (group CP) performed an exhaustive incremental bicycle ergometry...
October 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/29025830/randomised-controlled-pilot-trial-of-an-exercise-plus-behaviour-change-intervention-in-people-with-multiple-sclerosis-the-step-it-up-study
#2
Sara Hayes, Marcin Kacper Uszynski, Robert W Motl, Stephen Gallagher, Aidan Larkin, John Newell, Carl Scarrott, Susan Coote
OBJECTIVE: To investigate feasibility of multiple sclerosis (MS) exercise guidelines for inactive people with MS (PwMS) and to examine preliminary efficacy for walking. To investigate effect of augmenting that intervention with education based on social cognitive theory (SCT). DESIGN: Pilot multicentre, double-blind, randomised, parallel, controlled trial. SETTING: Community-delivered programme. PARTICIPANTS: Sixty-five physically inactive PwMS walked independently, scored 0-3 on the Patient Determined Disease Steps Scale, had no MS relapse or change in MS medication in 12 weeks...
October 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28991714/the-pharmacological-and-non-pharmacological-interventions-for-the-management-of-fatigue-related-multiple-sclerosis
#3
REVIEW
Philippa Miller, Andrew Soundy
AIM: The clinical aim was to provide up-to-date evidence-based recommendations for the treatment of MS-related fatigue (MSRF). The scientific aim was to prioritise topics for future randomised clinical trials with sufficient power. METHODS: A systematic search of review based research that considered MSRF in adults (18years and over) was undertaken in May 2016. Data from reviews was extracted, critically appraised and synthesised using four specific techniques. RESULTS: A total of 24 reviews were identified (17 non-pharmacological, 5 pharmacological, 2 combining both), which contained 339 studies on interventions deigned to improve MSRF...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28991096/evaluation-of-intervention-fidelity-in-a-multisite-clinical-trial-in-persons-with-multiple-sclerosis
#4
Janet D Morrison, Heather Becker, Alexa K Stuifbergen
BACKGROUND: Careful consideration of intervention fidelity is critical to establishing the validity and reliability of research findings, yet such reports are often lacking in the research literature. It is imperative that intervention fidelity be methodically evaluated and reported to promote the translation of effective interventions into sound evidence-based practice. PURPOSE: The purpose of this article is to explore strategies used to promote intervention fidelity, incorporating examples from a multisite clinical trial, that illustrate the National Institutes of Health Behavior Change Consortium's 5 domains for recommended treatment practices: (1) study design, (2) facilitator training, (3) intervention delivery, (4) intervention receipt, and (5) intervention enactment...
October 5, 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28949284/aerobic-exercise-cognitive-behavioural-therapy-and-energy-conservation-management-for-multiple-sclerosis-ms-fatigue-are-three-trials-better-than-one
#5
Rona Moss-Morris, Sam Norton
No abstract text is available yet for this article.
October 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28946576/the-effects-of-mat-pilates-and-reformer-pilates-in-patients-with-multiple-sclerosis-a-randomized-controlled-study
#6
I Bulguroglu, A Guclu-Gunduz, G Yazici, C Ozkul, C Irkec, B Nazliel, H Z Batur-Caglayan
BACKGROUND: Pilates is an exercise method which increases strength and endurance of core muscles and improves flexibility, dynamic postural control and balance. OBJECTIVE: To analyze and compare the effects of Mat and Reformer Pilates methods in Patients with Multiple Sclerosis (MS). METHODS: 38 patients with MS were included in the study. Participants were randomly divided into 3 groups as Mat Pilates, Reformer Pilates and control groups...
September 16, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28933610/exercise-interventions-in-multiple-sclerosis-rehabilitation-need-better-reporting-on-comorbidities-a-systematic-scoping-review
#7
Etienne J Bisson, Afolasade Fakolade, Julie Pétrin, Julie Lamarre, Marcia Finlayson
OBJECTIVE: To identify the extent to which exercise intervention studies in multiple sclerosis rehabilitation are addressing comorbidities and if researchers consider comorbidities as possible moderators or mediators of exercise outcomes. METHODS: Five databases were searched from inception to January 8, 2016, for exercise-related terms in combination with multiple sclerosis. Studies were screened and limited to randomized control trials, full text, and English language...
October 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28920890/exercise-in-patients-with-multiple-sclerosis
#8
REVIEW
Robert W Motl, Brian M Sandroff, Gert Kwakkel, Ulrik Dalgas, Anthony Feinstein, Christoph Heesen, Peter Feys, Alan J Thompson
Exercise can be a beneficial rehabilitation strategy for people with multiple sclerosis to manage symptoms, restore function, optimise quality of life, promote wellness, and boost participation in activities of daily living. However, this population typically engages in low levels of health-promoting physical activity compared with adults from the general population, a fact which has not changed in the past 25 years despite growing evidence of the benefits of exercise. To overcome this challenge, the main limitations to promoting exercise through the patient-clinician interaction must be addressed...
October 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28915856/exercise-prescription-for-patients-with-multiple-sclerosis-potential-benefits-and-practical-recommendations
#9
Farzin Halabchi, Zahra Alizadeh, Mohammad Ali Sahraian, Maryam Abolhasani
BACKGROUND: Multiple sclerosis (MS) can result in significant mental and physical symptoms, specially muscle weakness, abnormal walking mechanics, balance problems, spasticity, fatigue, cognitive impairment and depression. Patients with MS frequently decrease physical activity due to the fear from worsening the symptoms and this can result in reconditioning. Physicians now believe that regular exercise training is a potential solution for limiting the reconditioning process and achieving an optimal level of patient activities, functions and many physical and mental symptoms without any concern about triggering the onset or exacerbation of disease symptoms or relapse...
September 16, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28915343/identifying-preferred-format-and-source-of-exercise-information-in-persons-with-multiple-sclerosis-that-can-be-delivered-by-health-care-providers
#10
Yvonne C Learmonth, Brynn C Adamson, Julia M Balto, Chung-Yi Chiu, Isabel M Molina-Guzman, Marcia Finlayson, Barry J Riskin, Robert W Motl
BACKGROUND: There is increasing recognition of the benefits of exercise in individuals with multiple sclerosis (MS), yet the MS population does not engage in sufficient amounts of exercise to accrue health benefits. There has been little qualitative inquiry to establish the preferred format and source for receiving exercise information from health-care providers among persons with MS. OBJECTIVE: We sought to identify the desired and preferred format and source of exercise information for persons with MS that can be delivered through health-care providers...
October 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28900546/short-term-and-long-term-effects-of-an-exercise-based-patient-education-programme-in-people-with-multiple-sclerosis-a-pilot-study
#11
Christina Lutz, Stephanie Kersten, Christian T Haas
Background. Although people with Multiple Sclerosis (pwMS) benefit from physical exercise, they still show reduced physical activity and exercise behaviour. This study aimed to investigate short- and long-term effects of an exercise-based patient education programme (ePEP) that focuses on empowering pwMS to a sustainable and self-regulated exercise training management. Methods. Fourteen pwMS were randomly assigned to immediate experimental group (EG-I: n = 8) and waitlist-control group (EG-W: n = 6) and attended biweekly in a six-week ePEP...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/28888468/effect-of-visual-biofeedback-cycling-training-on-gait-in-patients-with-multiple-sclerosis
#12
A Hochsprung, A Granja Domínguez, E Magni, S Escudero Uribe, A Moreno García
INTRODUCTION: Gait alterations are present in a high percentage of patients with multiple sclerosis (MS). They appear from early stages of the disease and can limit patients' capacity to perform basic activities of daily living, affecting their quality of life. Visual biofeedback cycling training appears to be a useful tool in treating these impairments. This study aims to evaluate the short-term effect of visual biofeedback cycling training on gait in patients with MS. MATERIAL AND METHODS: A total of 61 patients with mild to moderate MS were randomly assigned to a control group and an intervention group...
September 6, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28885372/light-therapy-for-multiple-sclerosis-associated-fatigue-study-protocol-for-a-randomized-controlled-trial
#13
RANDOMIZED CONTROLLED TRIAL
Farrah J Mateen, Natalie C Manalo, Sara J Grundy, Melissa A Houghton, Gladia C Hotan, Hans Erickson, Aleksandar Videnovic
BACKGROUND: Fatigue is the most commonly reported symptom among multiple sclerosis (MS) patients, more than a quarter of whom consider fatigue to be their most disabling symptom. However, there are few effective treatment options for fatigue. We aim to investigate whether supplemental exposure to bright white light will reduce MS-associated fatigue. METHODS: Eligible participants will have clinically confirmed multiple sclerosis based on the revised McDonald criteria (2010) and a score ≥36 on the Fatigue Severity Scale (FSS)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28881147/cardiorespiratory-demand-of-acute-voluntary-cycling-with-functional-electrical-stimulation-in-individuals-with-multiple-sclerosis-with-severe-mobility-impairment
#14
Thomas Edwards, Robert W Motl, Lara A Pilutti
BACKGROUND: Exercise training is one strategy for improving cardiorespiratory fitness (CRF) in multiple sclerosis (MS), however, few modalities are accessible for those with severe mobility impairment. Functional electrical stimulation (FES) cycling is one adapted exercise modality with the potential for improving CRF in people with severe MS. OBJECTIVES: To characterize the cardiorespiratory response of acute voluntary cycling with FES in people with MS with severe mobility impairment, and to compare this response to passive leg cycling...
September 7, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28853641/management-of-the-symptoms-of-multiple-sclerosis-using-functional-electrical-stimulation-and-exercise
#15
Tamsyn Street
Previously, it was believed that exercise-related activity was likely to lead to the symptoms of multiple sclerosis (MS) becoming worse. More recently, it has been acknowledged that the consequences of not exercising are detrimental and may exacerbate symptoms of MS. In addition, it has been recognized that some of the disability that occurs after MS is likely to be due to deconditioning from a reduction in physical activity. The current paper will explore the potential role of functional electrical stimulation of the peroneal nerve, for facilitating neurorehabilitation, through increasing mobility and overcoming barriers to accessing exercise...
August 30, 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28830377/comprehensive-catwalk-gait-analysis-in-a-chronic-model-of-multiple-sclerosis-subjected-to-treadmill-exercise-training
#16
Danielle Bernardes, Alexandre Leite Rodrigues Oliveira
BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease with a wide range of symptoms including walking impairment and neuropathic pain mainly represented by mechanical allodynia. Noteworthy, exercise preconditioning may affect both walking impairment and mechanical allodynia. Most of MS symptoms can be reproduced in the animal model named experimental autoimmune encephalomyelitis (EAE). Usually, neurological deficits of EAE are recorded using a clinical scale based on the development of disease severity that characterizes tail and limb paralysis...
August 22, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28806143/whose-preferences-matter-a-patient-centered-approach-for-eliciting-treatment-goals
#17
Nananda F Col, Andrew J Solomon, Vicky Springmann, Calvin P Garbin, Carolina Ionete, Lori Pbert, Enrique Alvarez, Brenda Tierman, Ashli Hopson, Christen Kutz, Idanis Berrios Morales, Carolyn Griffin, Glenn Phillips, Long H Ngo
BACKGROUND: Patients facing a high-stakes clinical decision are often confronted with an overwhelming array of options. High-quality decisions about treatment should reflect patients' preferences as well as their clinical characteristics. Preference-assessment instruments typically focus on pre-selected clinical outcomes and attributes chosen by the investigator. OBJECTIVE: We sought to develop a patient-centered approach to elicit and compare the treatment goals of patients with multiple sclerosis (MS) and healthcare providers (HCPs)...
August 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28782878/physiological-measures-in-participants-with-chronic-fatigue-syndrome-multiple-sclerosis-and-healthy-controls-following-repeated-exercise-a-pilot-study
#18
L D Hodges, T Nielsen, D Baken
PURPOSE: To compare physiological responses of chronic fatigue syndrome (CFS/ME), multiple sclerosis (MS) and healthy controls (HC) following a 24-h repeated exercise test. METHODS: Ten CFS, seven MS and 17 age- and gender-matched healthy controls (10, CFS HC; and seven, MS HC) were recruited. Each participant completed a maximal incremental cycle exercise test on day 1 and again 24 h later. Heart rate (HR), blood pressure (BP), rating of perceived exertion (RPE), oxygen consumption (V˙O2), carbon dioxide production and workload (WL) were recorded...
August 7, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28768821/complementary-and-alternative-treatments-of-multiple-sclerosis-a-review-of-the-evidence-from-2001-to-2016
#19
REVIEW
Suzi B Claflin, Ingrid A F van der Mei, Bruce V Taylor
People with multiple sclerosis (PwMS) commonly use complementary and alternative medicines (CAM), but an understanding of their efficacy is lacking. Here, we quantitatively review the class I and class II studies of treatment efficacy for multiple sclerosis from January 2001 to January 2017, in order to assess the modern evidence for CAM use. The 38 studies included in this review are divided across five CAM types (cannabis, diet, exercise, psychological approaches and other). We found little evidence to support CAM efficacy...
August 2, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28758772/validation-of-the-godin-leisure-time-exercise-questionnaire-classification-coding-system-using-accelerometry-in-multiple-sclerosis
#20
Robert W Motl, Rachel E Bollaert, Brian M Sandroff
OBJECTIVE: There have been recent efforts toward creating a health contribution score (HCS) from the Godin Leisure-Time Exercise Questionnaire (GLTEQ) that reflects public-health guidelines for levels of moderate-to-vigorous physical activity (MVPA). The HCS yields categories of insufficiently active (less substantial or low benefits), moderately active (some benefits), and active (substantial benefits). The present study examined the validity of the GLTEQ HCS and its categories as reflecting levels of MVPA in multiple sclerosis (MS)...
July 31, 2017: Rehabilitation Psychology
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