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Multiple sclerosis and exercise

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https://www.readbyqxmd.com/read/28631984/effect-of-exercise-interventions-on-perceived-fatigue-in-people-with-multiple-sclerosis-synthesis-of-meta-analytic-reviews
#1
Reza Safari, Marietta L Van der Linden, Tom H Mercer
Although exercise training has been advocated as a nonpharmacological treatment for multiple sclerosis (MS) related fatigue, no consensus exists regarding its effectiveness. To address this, we collated meta-analytic reviews that explored the effectiveness of exercise training for the treatment of MS-related fatigue. We searched five online databases for relevant reviews, published since 2005, and identified 172 records. Five reviews were retained for systematic extraction of information and evidence quality analysis...
June 20, 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28629268/comparing-the-effect-of-cawthorne-cooksey-and-frenkel-exercises-on-balance-in-patients-with-multiple-sclerosis-a-randomized-controlled-trial
#2
Ardashir Afrasiabifar, Fatemeh Karami, Shahla Najafi Doulatabad
OBJECTIVE: To evaluate the effect of Cawthorne-Cooksey and Frenkel exercises on balance in patients with multiple sclerosis. DESIGN: It was a three-arm parallel randomized controlled trial study. SETTING: Outpatient clinic. SUBJECTS: Patients with multiple sclerosis. INTERVENTIONS: Subjects in the intervention groups completed a 12-week program consisted of Cawthorne-Cooksey or Frenkel exercises...
June 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28616851/effect-of-aerobic-interval-training-on-serum-il-10-tnf%C3%AE-and-adipokines-levels-in-women-with-multiple-sclerosis-possible-relations-with-fatigue-and-quality-of-life
#3
Motahare Mokhtarzade, Rouholah Ranjbar, Nastaran Majdinasab, Darpan Patel, Mehdieh Molanouri Shamsi
PURPOSE: Multiple sclerosis is associated with immune system dysfunction and chronic inflammation; however, possible relations between immunologic and metabolic factors and some psychological indexes such as fatigue and quality of life, especially in relation to exercise training, have not yet been investigated. The present study was designed to investigate the effect of aerobic interval training on interleukin-10/tumor necrosis factor ratio and adipokine (leptin and adiponectin) concentrations in women with multiple sclerosis...
June 14, 2017: Endocrine
https://www.readbyqxmd.com/read/28616252/important-considerations-for-feasibility-studies-in-physical-activity-research-involving-persons-with-multiple-sclerosis-a-scoping-systematic-review-and-case-study
#4
Yvonne C Learmonth, Robert W Motl
BACKGROUND: Much research has been undertaken to establish the important benefits of physical activity in persons with multiple sclerosis (MS). There is disagreement regarding the strength of this research, perhaps because the majority of studies on physical activity and its benefits have not undergone initial and systematic feasibility testing. We aim to address the feasibility processes that have been examined within the context of physical activity interventions in MS. METHOD: A systematic scoping review was conducted based on a literature search of five databases to identify feasibility processes described in preliminary studies of physical activity in MS...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28614793/a-single-dose-of-cannabidiol-reduces-blood-pressure-in-healthy-volunteers-in-a-randomized-crossover-study
#5
Khalid A Jadoon, Garry D Tan, Saoirse E O'Sullivan
BACKGROUND: Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid used in multiple sclerosis and intractable epilepsies. Preclinical studies show CBD has numerous cardiovascular benefits, including a reduced blood pressure (BP) response to stress. The aim of this study was to investigate if CBD reduces BP in humans. METHODS: Nine healthy male volunteers were given 600 mg of CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study. Cardiovascular parameters were monitored using a finometer and laser Doppler...
June 15, 2017: JCI Insight
https://www.readbyqxmd.com/read/28606714/effect-of-physical-exercise-on-brain-and-lipid-metabolism-in-mouse-models-of-multiple-sclerosis
#6
REVIEW
Léo Houdebine, Cristina Anna Gallelli, Marialetizia Rastelli, Nirmal Kumar Sampathkumar, Julien Grenier
Multiple sclerosis (MS) is a central nervous demyelinating disease characterized by cyclic loss and repair of myelin sheaths associated with chronic inflammation and neuronal loss. This degenerative pathology is accompanied by modified levels of oxysterols (oxidative derivatives of cholesterol, implicated in cholesterol metabolism), highlighted in the brain, blood and cerebrospinal fluid of MS patients. The pathological accumulation of such derivatives is thought to participate in the onset and progression of the disease through their implication in inflammation, oxidative stress, demyelination and neurodegeneration...
June 9, 2017: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/28603459/outcomes-after-functional-electrical-stimulation-cycle-training-in-individuals-with-multiple-sclerosis-who-are-nonambulatory
#7
Deborah Backus, Blake Burdett, Laura Hawkins, Christine Manella, Kevin K McCully, Mark Sweatman
BACKGROUND: Exercise is safe and beneficial for people with multiple sclerosis (MS). Functional electrical stimulation (FES) cycling offers people with significant weakness and mobility challenges an option for exercise. We sought to evaluate the safety of FES cycling and its potential to improve fatigue, pain, spasticity, and quality of life in people with moderate-to-severe MS. METHODS: Sixteen participants with MS who were nonambulatory cycled for 30 minutes two to three times a week for 1 month...
May 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28602542/moderators-of-exercise-effects-on-depressive-symptoms-in-multiple-sclerosis-a-meta-regression
#8
REVIEW
Matthew P Herring, Karl M Fleming, Sara P Hayes, Robert W Motl, Susan B Coote
CONTEXT: This study examined the extent to which patient and trial characteristics moderate the effects of exercise on depressive symptoms among people with multiple sclerosis. EVIDENCE ACQUISITION: Twenty-four effects were derived from 14 articles published before August 2016 located using Google Scholar, MEDLINE, PsycINFO, PubMed, and Web of Science. Trials involved 624 people with multiple sclerosis and included both randomization to exercise training or a non-exercise control condition and measurement of depressive symptoms at baseline and at mid- and/or post-intervention...
June 8, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28565895/quality-of-the-tools-used-to-assess-aerobic-capacity-in-persons-with-multiple-sclerosis-a-systematic-review
#9
Maxime Valet, Thierry Lejeune, Jean C Hakizimana, Gaëtan Stoquart
BACKGROUND: Assessments of physical fitness, including exercise tolerance functions, are valuable in persons with Multiple Sclerosis (MS). Many tools with widely varying advantages and disadvantages have been used to assess physical fitness in research and clinical practice. To date, there are no recommendations regarding the best tools to use for this purpose in persons with MS. AIM: This study aimed to systematically review the psychometric properties of the tools used to assess exercise tolerance functions in persons with MS and to propose recommendations regarding the best test to use...
May 31, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28555454/-cognitive-training-combined-with-aerobic-exercises-in-multiple-sclerosis-patients-a-pilot-study
#10
R M Jimenez-Morales, L F Herrera-Jimenez, Y Macias-Delgado, Y T Perez-Medinilla, S M Diaz-Diaz, C Forn
INTRODUCTION: The scientific evidences associated to the effectiveness of different techniques of cognitive rehabilitation are still contradictory. AIM: To compare a program of combined training (physical and cognitive) in front of a program of physical training and to observe their effectiveness about the optimization of the cognitive functions in patients with multiple sclerosis (MS). PATIENTS AND METHODS: It was carried out an experimental study in 32 patients with MS...
June 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28527234/impaired-postural-balance-correlates-with-complex-walking-performance-in-mildly-disabled-persons-with-multiple-sclerosis
#11
John Brincks, Elisabeth Due Andersen, Henrik Sørensen, Ulrik Dalgas
BACKGROUND: It is relevant to understand the possible influence of impaired postural balance on walking performance in multiple sclerosis (MS) gait rehabilitation. OBJECTIVE: We expected associations between impaired postural balance and complex walking performance in mildly disabled persons with MS, but not in healthy controls. METHODS: Thirteen persons with MS (Expanded Disability Status Scale = 2.5) and 13 healthy controls' walking performance were measured at fast walking speed, Timed Up & Go and Timed 25 Feet Walking...
May 13, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28524732/investigating-the-needs-and-wants-of-healthcare-providers-for-promoting-exercise-in-persons-with-multiple-sclerosis-a-qualitative-study
#12
Yvonne C Learmonth, Brynn C Adamson, Julia M Balto, Chung-Yi Chiu, Isabel M Molina-Guzman, Marcia Finlayson, Elizabeth A Barstow, Robert W Motl
PURPOSE: We undertook a qualitative study that explored the needs of healthcare providers for promoting exercise behaviour among persons with mild or moderate multiple sclerosis (MS). METHODS: We used interpretive description methodology, and conducted semi-structured interviews with Neurologists (n = 13), occupational therapists (n = 10), physical therapists (n = 11), and nurses (n = 10). The interviews were analysed using thematic analysis. RESULTS: We identified three themes with multiple subthemes regarding exercise promotion by healthcare providers...
May 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28488333/afferent-thermosensory-function-in-relapsing-remitting-multiple-sclerosis-following-exercise-induced-increases-in-body-temperature
#13
Davide Filingeri, Georgia Chaseling, Phu Hoang, Michael Barnett, Scott L Davis, Ollie Jay
What is the central question of this study? Between 60 and 80% of multiple sclerosis (MS) patients experience transient worsening of symptoms with increased body temperature (heat sensitivity). As sensory abnormalities are common in MS, we asked whether afferent thermosensory function is altered in MS following exercise-induced increases in body temperature. What is the main finding and its importance? Increases in body temperature of as little as ∼0.4°C were sufficient to decrease cold, but not warm, skin thermosensitivity (∼10%) in MS, across a wider temperature range than in age-matched healthy individuals...
May 10, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28475409/commitment-to-physical-activity-and-health-a-case-study-of-a-paralympic-gold-medallist
#14
Bridie Kean, Florin Oprescu, Marion Gray, Brendan Burkett
BACKGROUND: Physical activity has been documented as both beneficial and detrimental for individuals with multiple sclerosis (MS). The varied experience highlights challenges associated with physical activity and MS, requiring a greater understanding of the experiences of exercise for individuals with MS. OBJECTIVE: The purpose of this study was to explore how physical activity played a role in the life of a Paralympic Gold medallist. Carol was diagnosed with MS and went onto achieve the highest accolade in Paralympic sport...
May 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28462574/influence-of-aquatic-exercises-in-physical-condition-in-patients-with-multiple-sclerosis
#15
Felipe J Aidar, Dihogo Gama de Matos, Raphael F de Souza, Aline Batista Gomes, Francisco Saavedra, Nuno Garrido, André L Carneiro, Victor Reis
BACKGROUND: Multiple Sclerosis (MS) is a disabling chronic disease of the nervous system in which the myelin system of the central nervous system is deteriorated. PURPOSE: This study aimed to evaluate the effectiveness of an aquatic exercise program on the physical condition of patients suffering from multiple sclerosis. METHODS: The study included 26 participants divided into two groups: an experimental group (EG) with 13 individuals and a control group (CG) also with 13 individuals...
April 28, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28461167/singing-lessons-for-respiratory-health-a-literature-review
#16
REVIEW
Rachel B Goldenberg
OBJECTIVE: Several studies have explored the role of music and singing as a treatment for respiratory symptoms. The objective of this paper was to review the current body of literature in regard to the use of singing as both a physiological and a psychological therapy for respiratory disease and assess the role the singing teacher might play in this treatment. STUDY DESIGN: This is a literature review, discussion of results and directions for further research. METHOD: Multiple databases were searched using keywords such as "respiratory," "physiotherapy," and "pulmonary" in conjunction with "singing...
April 28, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28445083/fatigue-and-physical-functioning-in-children-with-multiple-sclerosis-and-acute-disseminated-encephalomyelitis
#17
Leontien Cc Toussaint-Duyster, Yu Yi M Wong, Monique Hm Van der Cammen-van Zijp, Daniëlle Van Pelt-Gravesteijn, Coriene E Catsman-Berrevoets, Rogier Q Hintzen, Rinze F Neuteboom
BACKGROUND AND OBJECTIVE: Fatigue and physical impairments are a major concern in children with multiple sclerosis (MS) and after acute disseminated encephalomyelitis (post-ADEM). We here aimed to evaluate the interaction between fatigue, exercise capacity, motor performance, neurological status, and quality of life (HRQoL). METHODS: In this cross-sectional study, data of 38 children (MS n = 22, post-ADEM n = 16), aged 4-17 years attending our national pediatric MS center, were studied...
April 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28441894/self-directed-exercise-in-multiple-sclerosis-evaluation-of-a-home-automated-tele-management-system
#18
Susan S Conroy, Min Zhan, William J Culpepper, Walter Royal, Mitchell T Wallin
Introduction Physical rehabilitation is one of the few non-pharmaceutical therapies for maintaining or improving walking ability for patients with multiple sclerosis. However, travel distance to rehabilitation clinics, neurological disability and insurance coverage often limit access to specialised rehabilitation services. To address these issues, we utilised a web-based system to support a home-based self-directed exercise programme. Methods Patients ( n = 24) were randomised to either routine home rehabilitation or to the multiple sclerosis home automated tele-management system for a six-month period...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28434551/neuromuscular-fatigue-during-exercise-methodological-considerations-etiology-and-potential-role-in-chronic-fatigue
#19
REVIEW
Rosie Twomey, Saied Jalal Aboodarda, Renata Kruger, Susan Nicole Culos-Reed, John Temesi, Guillaume Y Millet
The term fatigue is used to describe a distressing and persistent symptom of physical and/or mental tiredness in certain clinical populations, with distinct but ultimately complex, multifactorial and heterogenous pathophysiology. Chronic fatigue impacts on quality of life, reduces the capacity to perform activities of daily living, and is typically measured using subjective self-report tools. Fatigue also refers to an acute reduction in the ability to produce maximal force or power due to exercise. The classical measurement of exercise-induced fatigue involves neuromuscular assessments before and after a fatiguing task...
April 20, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28427699/people-with-ms-are-less-physically-active-than-healthy-controls-but-as-active-as-those-with-other-chronic-diseases-an-updated-meta-analysis
#20
D Kinnett-Hopkins, B Adamson, K Rougeau, R W Motl
BACKGROUND: There has been remarkable growth in research examining physical activity behavior (any bodily movement produced by skeletal muscle contraction that results in energy expenditure) among people living with multiple sclerosis (MS) over the past decade. The current meta-analysis quantified physical activity participation levels in persons with MS compared with non-diseased and other clinical populations. METHODS: We searched PUBMED, PsycINFO and Web of Science using the keywords physical activity, exercise, and physical fitness in conjunction with MS...
April 2017: Multiple Sclerosis and related Disorders
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