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Multiple sclerosis and exercise

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https://www.readbyqxmd.com/read/28806143/whose-preferences-matter-a-patient-centered-approach-for-eliciting-treatment-goals
#1
Nananda F Col, Andrew J Solomon, Vicky Springmann, Calvin P Garbin, Carolina Ionete, Lori Pbert, Enrique Alvarez, Brenda Tierman, Ashli Hopson, Christen Kutz, Idanis Berrios Morales, Carolyn Griffin, Glenn Phillips, Long H Ngo
BACKGROUND: Patients facing a high-stakes clinical decision are often confronted with an overwhelming array of options. High-quality decisions about treatment should reflect patients' preferences as well as their clinical characteristics. Preference-assessment instruments typically focus on pre-selected clinical outcomes and attributes chosen by the investigator. OBJECTIVE: We sought to develop a patient-centered approach to elicit and compare the treatment goals of patients with multiple sclerosis (MS) and healthcare providers (HCPs)...
August 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28782878/physiological-measures-in-participants-with-chronic-fatigue-syndrome-multiple-sclerosis-and-healthy-controls-following-repeated-exercise-a-pilot-study
#2
L D Hodges, T Nielsen, D Baken
PURPOSE: To compare physiological responses of chronic fatigue syndrome (CFS/ME), multiple sclerosis (MS) and healthy controls (HC) following a 24-h repeated exercise test. METHODS: Ten CFS, seven MS and 17 age- and gender-matched healthy controls (10, CFS HC; and seven, MS HC) were recruited. Each participant completed a maximal incremental cycle exercise test on day 1 and again 24 h later. Heart rate (HR), blood pressure (BP), rating of perceived exertion (RPE), oxygen consumption (V˙O2), carbon dioxide production and workload (WL) were recorded...
August 7, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28768821/complementary-and-alternative-treatments-of-multiple-sclerosis-a-review-of-the-evidence-from-2001-to-2016
#3
REVIEW
Suzi B Claflin, Ingrid A F van der Mei, Bruce V Taylor
People with multiple sclerosis (PwMS) commonly use complementary and alternative medicines (CAM), but an understanding of their efficacy is lacking. Here, we quantitatively review the class I and class II studies of treatment efficacy for multiple sclerosis from January 2001 to January 2017, in order to assess the modern evidence for CAM use. The 38 studies included in this review are divided across five CAM types (cannabis, diet, exercise, psychological approaches and other). We found little evidence to support CAM efficacy...
August 2, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28758772/validation-of-the-godin-leisure-time-exercise-questionnaire-classification-coding-system-using-accelerometry-in-multiple-sclerosis
#4
Robert W Motl, Rachel E Bollaert, Brian M Sandroff
OBJECTIVE: There have been recent efforts toward creating a health contribution score (HCS) from the Godin Leisure-Time Exercise Questionnaire (GLTEQ) that reflects public-health guidelines for levels of moderate-to-vigorous physical activity (MVPA). The HCS yields categories of insufficiently active (less substantial or low benefits), moderately active (some benefits), and active (substantial benefits). The present study examined the validity of the GLTEQ HCS and its categories as reflecting levels of MVPA in multiple sclerosis (MS)...
July 31, 2017: Rehabilitation Psychology
https://www.readbyqxmd.com/read/28755682/the-effect-of-exercise-training-in-adults-with-multiple-sclerosis-with-severe-mobility-disability-a-systematic-review-and-future-research-directions
#5
REVIEW
Thomas Edwards, Lara A Pilutti
INTRODUCTION: There is evidence for the benefits of exercise training in persons with multiple sclerosis (MS). However, these benefits have primarily been established in individuals with mild-to-moderate disability (i.e., Expanded Disability Status Scale [EDSS] scores 1.0-5.5), rather than among those with significant mobility impairment. Further, the approaches to exercise training that have been effective in persons with mild-to-moderate MS disability may not be physically accessible for individuals with mobility limitations...
August 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28744060/effects-of-physiotherapy-treatment-for-urinary-incontinence-in-patient-with-multiple-sclerosis
#6
Carla Maria de Abreu Pereira, Mariane Castiglione, Karina Tamy Kasawara
[Purpose] The aim of the study was to evaluate the benefits of physical therapy for urinary incontinence in patients with multiple sclerosis and to verify the impact of urinary incontinence on the patient's quality of life. [Subject and Methods] A case study of a 55-year-old female patient diagnosed with multiple sclerosis and mixed urinary incontinence was conducted. Physical therapy sessions were conducted once a week, in total 15 sessions, making use of targeted functional electrical vaginal stimulation, along with active exercises for the pelvic floor muscles and electrical stimulation of the posterior tibial nerve, behavioral rehabilitation and exercise at home...
July 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28735720/a-randomized-controlled-trial-to-examine-the-impact-of-aquatic-exercise-training-on-functional-capacity-balance-and-perceptions-of-fatigue-in-female-patients-with-multiple-sclerosis
#7
Mehdi Kargarfard, Ardalan Shariat, Lee Ingle, Joshua A Cleland, Mina Kargarfard
OBJECTIVE: To assess the effects of 8-weeks aquatic exercise training program on functional capacity, balance, and perceptions of fatigue in women with multiple sclerosis (MS). DESIGN: A randomized controlled design. SETTING: Referral center of a multiple sclerosis society. PARTICIPANTS: Women (age: 36.4 ±8.2) diagnosed with relapsing-remitting (RR-type) MS. After undergoing baseline testing by a neurologist, participants were allocated to either an intervention (aquatic training program) or a control group...
July 20, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28735565/can-pharmacological-manipulation-of-ltp-favor-the-effects-of-motor-rehabilitation-in-multiple-sclerosis
#8
Mario Stampanoni Bassi, Letizia Leocani, Giancarlo Comi, Ennio Iezzi, Diego Centonze
BACKGROUND: Synaptic plasticity, the basic mechanism of clinical recovery after brain lesion, can also remarkably influence the clinical course of multiple sclerosis (MS). Physical rehabilitation represents the main treatment option to promote synaptic long-term potentiation (LTP) and to enhance spontaneous recovery of neurological deficits. OBJECTIVES: To overview the role of pharmacological treatment and physical rehabilitation in modulating LTP and enhancing clinical recovery in MS...
July 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28732757/multimodal-exercise-training-in-multiple-sclerosis-a-randomized-controlled-trial-in-persons-with-substantial-mobility-disability
#9
Brian M Sandroff, Rachel E Bollaert, Lara A Pilutti, Melissa L Peterson, Tracy Baynard, Bo Fernhall, Edward McAuley, Robert W Motl
BACKGROUND: Mobility disability is a common, debilitating feature of multiple sclerosis (MS). Exercise training has been identified as an approach to improve MS-related mobility disability. However, exercise randomized controlled trials (RCTs) on mobility in MS have generally not selectively targeted those with the onset of irreversible mobility disability. OBJECTIVES: The current multi-site RCT compared the efficacy of 6-months of supervised, multimodal exercise training with an active control condition for improving mobility, gait, physical fitness, and cognitive outcomes in persons with substantial MS-related mobility disability...
July 19, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28697504/effects-of-a-training-program-involving-body-cooling-on-physical-and-cognitive-capacities-and-quality-of-life-in-multiple-sclerosis-patients-a-pilot-study
#10
Benoit Gonzales, Gilles Chopard, Benjamin Charry, Eric Berger, Julien Tripard, Eloi Magnin, Alain Groslambert
OBJECTIVE: Two methods using exercise and body cooling could influence the well-being of patients with multiple sclerosis (PwMS). The aim of this study was to determine whether wearing a cooling vest during a physical training program could increase the cognitive and physical capacities and quality of life in PwMS. METHODS: Eighteen PwMS (49.6 ± 8 years; Expanded Disability Status Score 5.0 ± 1.0) were randomly assigned to a cooling or control group. PwMS underwent a 7-week physical training program...
2017: European Neurology
https://www.readbyqxmd.com/read/28695416/sources-of-variability-in-physical-activity-among-inactive-people-with-multiple-sclerosis
#11
Marcin K Uszynski, Matthew P Herring, Blathin Casey, Sara Hayes, Stephen Gallagher, Robert W Motl, Susan Coote
PURPOSE: Evidence supports that physical activity (PA) improves symptoms of multiple sclerosis (MS). Although application of principles from Social Cognitive Theory (SCT) may facilitate positive changes in PA behaviour among people with multiple sclerosis (pwMS), the constructs often explain limited variance in PA. This study investigated the extent to which MS symptoms, including fatigue, depression, and walking limitations combined with the SCT constructs, explained more variance in PA than SCT constructs alone among pwMS...
July 10, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28687973/effect-of-exercise-therapy-on-quality-of-life-of-patients-with-multiple-sclerosis-in-iran-a-systematic-review-and-meta-analysis
#12
REVIEW
Abolhassan Afkar, Asieh Ashouri, Marjan Rahmani, Abdolhosein Emami Sigaroudi
Multiple sclerosis (MS) is a chronic and progressive disease charachterized by disabilities which adversely affect individuals' quality of life (QOL). In the present study, the effect size of exercise therapy on patients' QOL in both physical and mental dimensions were investigated and the moderator effect of a number of selected theoretical and significant practical variables were assessed. Relevant studies, published before July 2015, were identified by searching PubMed, Scopus, Google scholar, and Persian medical databases including IranMedex, Irandoc, Magiran, Scientific Information Database (SID), and Medlib...
July 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28681596/high-intensity-interval-training-combined-with-resistance-training-improves-physiological-capacities-strength-and-quality-of-life-in-multiple-sclerosis-patients-a-pilot-study
#13
Pierre Zaenker, Fabrice Favret, Evelyne Lonsdorfer, Guillaume Muff, Jérôme DE Seze, Marie-Eve Isner-Horobeti
BACKGROUND: Numerous studies have shown that mild-to-moderate intensity or resistance exercise training improves physical capacities such as, peak oxygen consumption, maximal tolerated power and strength in multiple sclerosis patients. However, few studies have evaluated the effects of high intensity interval training associated to with resistance training. Only few studies have analysed difference between men and women before and after combined training. Moreover, the evaluation of exercise between ambulatory multiple sclerosis patients without disability (EDSS 0- 3) and patients with disabilities (EDSS 3...
July 5, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28669032/immunosenescence-the-role-of-aging-in-the-predisposition-to-neuro-infectious-complications-arising-from-the-treatment-of-multiple-sclerosis
#14
REVIEW
Elena Grebenciucova, Joseph R Berger
PURPOSE OF REVIEW: This review highlights some of the important changes in the immune system that occur in the process of normal aging. Immunosenescence as a concept is directly relevant to the world of neuro-inflammation, as it may be a contributing factor to the risks associated with some of the current immunosuppressive and immunomodulatory therapies used in treating multiple sclerosis (MS) and other inflammatory disorders. RECENT FINDINGS: Profound qualitative and quantitative changes occur in the adaptive and innate immunity compartments during aging...
August 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28655386/rhabdomyolysis-and-interferon-%C3%AE-case-report-and-short-review
#15
Alexander Jerman, Damjan Kovač, Željka Večerić-Haler, Alojzija Hočevar, Ajda Ota, Sanela Banović, Jelka Lindič
BACKGROUND: We present a case of acute rhabdomyolysis in the setting of interferon-β treatment and concomitant pomelo juice ingestion, with concern of possible pharmacological interaction, which has not yet been described in the literature. CASE PRESENTATION: A young Caucasian female with multiple sclerosis on chronic therapy with interferon-β presented with acute rhabdomyolysis after mild exercise and concomitant ingestion of pomelo extract. After stopping the suspected drugs, the signs of rhabdomyolysis diminished, the subsequent course was favorable...
2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28648682/a-qualitative-investigation-of-exercise-perceptions-and-experiences-in-people-with-multiple-sclerosis-before-during-and-after-participation-in-a-personally-tailored-exercise-program
#16
Helen Crank, Anouska Carter, Liam Humphreys, Nicky Snowdon, Amanda Daley, Nicola Woodroofe, Basil Sharrack, Jane Petty, John M Saxton
OBJECTIVE: To undertake a qualitative investigation of exercise perceptions and experiences in people with MS (PwMS) before, during and after participation in a personally-tailored program designed to promote long-term maintenance of self-directed exercise. DESIGN: Focus groups and semi-structured telephone interviews. SETTING: University Exercise Science Department close to the recruiting hospital. PARTICIPANTS: PwMS (N=33; aged 47...
June 22, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28646860/effect-of-exercising-at-minimum-recommendations-of-the-multiple-sclerosis-exercise-guideline-combined-with-structured-education-or-attention-control-education-secondary-results-of-the-step-it-up-randomised-controlled-trial
#17
Susan Coote, Marcin Uszynski, Matthew P Herring, Sara Hayes, Carl Scarrott, John Newell, Stephen Gallagher, Aidan Larkin, Robert W Motl
BACKGROUND: Recent exercise guidelines for people with multiple sclerosis (MS) recommend a minimum of 30 min moderate intensity aerobic exercise and resistance exercise twice per week. This trial compared the secondary outcomes of a combined 10-week guideline based intervention and a Social Cognitive Theory (SCT) education programme with the same exercise intervention involving an attention control education. METHODS: Physically inactive people with MS, scoring 0-3 on Patient Determined Disease Steps Scale, with no MS relapse or change in MS medication, were randomised to 10-week exercise plus SCT education or exercise plus attention control education conditions...
June 24, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28631984/effect-of-exercise-interventions-on-perceived-fatigue-in-people-with-multiple-sclerosis-synthesis-of-meta-analytic-reviews
#18
Reza Safari, Marietta L Van der Linden, Tom H Mercer
Although exercise training has been advocated as a nonpharmacological treatment for multiple sclerosis (MS) related fatigue, no consensus exists regarding its effectiveness. To address this, we collated meta-analytic reviews that explored the effectiveness of exercise training for the treatment of MS-related fatigue. We searched five online databases for relevant reviews, published since 2005, and identified 172 records. Five reviews were retained for systematic extraction of information and evidence quality analysis...
June 20, 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28629268/comparing-the-effect-of-cawthorne-cooksey-and-frenkel-exercises-on-balance-in-patients-with-multiple-sclerosis-a-randomized-controlled-trial
#19
Ardashir Afrasiabifar, Fatemeh Karami, Shahla Najafi Doulatabad
OBJECTIVE: To evaluate the effect of Cawthorne-Cooksey and Frenkel exercises on balance in patients with multiple sclerosis. DESIGN: It was a three-arm parallel randomized controlled trial study. SETTING: Outpatient clinic. SUBJECTS: Patients with multiple sclerosis. INTERVENTIONS: Subjects in the intervention groups completed a 12-week program consisted of Cawthorne-Cooksey or Frenkel exercises...
June 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28616851/effect-of-aerobic-interval-training-on-serum-il-10-tnf%C3%AE-and-adipokines-levels-in-women-with-multiple-sclerosis-possible-relations-with-fatigue-and-quality-of-life
#20
Motahare Mokhtarzade, Rouholah Ranjbar, Nastaran Majdinasab, Darpan Patel, Mehdieh Molanouri Shamsi
PURPOSE: Multiple sclerosis is associated with immune system dysfunction and chronic inflammation; however, possible relations between immunologic and metabolic factors and some psychological indexes such as fatigue and quality of life, especially in relation to exercise training, have not yet been investigated. The present study was designed to investigate the effect of aerobic interval training on interleukin-10/tumor necrosis factor ratio and adipokine (leptin and adiponectin) concentrations in women with multiple sclerosis...
August 2017: Endocrine
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