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Adenoids in children

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https://www.readbyqxmd.com/read/29649882/local-atopy-in-childhood-adenotonsillar-hypertrophy
#1
Kyu-Sup Cho, Seong Heon Kim, Sung-Lyong Hong, Jaeyoung Lee, Sue Jean Mun, Young Eun Roh, Young Mi Kim, Hye-Young Kim
Background Although the cause of adenotonsillar hypertrophy remains unknown, some studies have shown that allergy may be a risk factor. Purpose This study determined the levels of allergen-specific immunoglobulin E (sIgE) in the adenotonsillar tissues of children with adenotonsillar hypertrophy and evaluated the clinical significance of local atopy in adenotonsillar tissues. Methods We measured 21 types of specific immunoglobulin E in the serum and adenotonsillar tissues of 102 children with adenotonsillar hypertrophy and compared the sensitization patterns of the serum and local tissues...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29605362/can-the-number-of-eosinophils-in-adenoid-and-tonsil-tissue-determine-the-allergy-in-children
#2
Nur Yucel Ekici, Orhan Görgülü, Gül Yucel, Özgür Külahcı, Osman Kürşat Arıkan, Cemile Durmaz
OBJECTIVE: Previous reports have indicated the association of allergy with Waldeyer's ring. The aim of this prospective study was to evaluate the correlation between the allergy and the number of eosinophils in the adenoid and tonsil tissue. METHODS: 101 children who were underwent adenoidectomy and/or tonsillectomy were prospectively enrolled in this study. 46 children who had positive skin-prick test for at least one of the allergen panel were sensitized and 55 children were nonsensitized as a result of skin-prick test...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29605360/grommet-and-adenoid-pain-evaluation-grape-study
#3
Lammens F, Boons J, Michiels E, Beckers K, Laureyns G, Indesteege J, Indesteege F, Lemmens W, Lemkens N, Jans F, Jorissen M, Lemkens P
In the GRAPE study an analysis is made of postoperative pain sensation in children between 6 months and 6 years after adenotomy and placement of ear grommets. Intraoperative treatment with paracetamol versus placebo shows no statistically significant difference in pain between both groups indicating that this type of surgery causes little discomfort and does not require specific intraoperative analgesic treatment.
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29600829/our-experience-of-the-necessity-of-adenoidectomy-or-adenotonsillectomy-at-the-time-of-ventilation-tube-insertion-in-11-941-children-with-middle-ear-effusion
#4
James Johnston, Gabrielle Kinzett-Carran, Murali Mahadevan, Richard G Douglas
Adenoidectomy and tonsillectomy are commonly performed at the time of myringotomy plus ventilation tube insertion (MVTI) in children with otitis media with effusion (OME). However, the evidence supporting this practice is not conclusive. This is because uncertainty remains regarding the pathogenic role of the adenoids in OME. It is unclear if mechanical obstruction is a more or less important factor than the adenoids' role as a bacterial reservoir. Some studies show that children who have large adenoids removed have higher rates of effusion resolution compared to those children with small adenoids...
March 30, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29595664/roles-of-t-follicular-helper-cells-in-the-pathogenesis-of-adenoidal-hypertrophy-combined-with-secretory-otitis-media
#5
Chunyan Feng, Qicheng Zhang, Guangquan Zhou, Jing Zhang, Yanshu Zhang
The aim of this study was to investigate the roles of T follicular helper (Tfh) cells in secretory otitis media (SOM) combined with adenoidal hypertrophy (AH).Patients with AH or AH combined with SOM admitted to the Yancheng No. 1 People's Hospital from December 2012 to December 2014 were included. Fourteen age-matched healthy individuals received physical examinations in the hospital served as control. The venous Tfh was determined using flow cytometry, and CD3 + CD4 + CXCR5 + T lymphocytes were defined as Tfh cells...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29525823/topical-blood-stopper-agents-during-adenoid-surgery-in-young-children-a-prospective-randomized-controlled-trial
#6
Randa A Abdallah, Sameh M Ragab, Maher Z Hassanin
OBJECTIVE: To investigate the safety and efficacy of two topical blood stopper modulators; Ankaferd blood stopper (ABS) and feracrylum 1% solution (FS) during adenoid surgery. STUDY DESIGN: Prospective randomized trial. METHODS: Two hundred and twenty five consecutive pediatric adenoid patients aged from 9 months to 2 years old were studied. Patients were randomly allocated into two haemostatic groups; (ABS, FS) and normal saline (control group)...
March 10, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29501304/sleep-endoscopy-findings-in-children-with-persistent-obstructive-sleep-apnea-after-adenotonsillectomy
#7
Steven W Coutras, Alexander Limjuco, Kristin E Davis, Michele M Carr
OBJECTIVES: Describe the patterns of obstruction in persistent pediatric OSA and their relationship with patient weight. STUDY DESIGN: Retrospective review. METHODS: All pediatric DISE procedures performed at a tertiary care hospital between October 2010 and October 2015 were reviewed. Patients had polysomnography after adenotonsillectomy that confirmed persistent obstructive sleep apnea (OSA). Variables included age, gender, co-morbidities, and AHI...
April 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29500040/innate-immunity-gene-expression-by-epithelial-cells-of-upper-respiratory-tract-in-children-with-adenoid-hypertrophy
#8
Lyudmila Viktorovna Gankovskaya, Valentina Pavlovna Bykova, Leila Seimurovna Namasova-Baranova, Alexander Viktorovich Karaulov, Irina Viktorovna Rahmanova, Viktor Anatolievich Gankovskii, Catherine Dmitrievna Merkushova, Oksana Anatolievna Svitich
BACKGROUND: A major role of the innate immunity in the defence of mucosal tissue is well established. However, a balance between the main components of the immunity such as toll-like receptors (TLRs) and defensins in the pathology of upper respiratory tract in children has not been addressed yet. Our aim was to investigate the gene expression of some TLRs as well as alpha and beta-defensins in children suffered from adenoid hyperthrophy in comparison with healthy children. METHODS: Samples (nasal epithelium and adenoids) from patients with hypertrophic adenoids (n = 77) and control group (n = 33) were investigated...
February 27, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29471795/superficial-punctate-keratopathy-in-a-pediatric-patient-was-related-to-adenoid-hypertrophy-and-obstructive-sleep-apnea-syndrome-a-case-report
#9
Ying-Ying Gao, Hong-Juan Wang, You Wu
BACKGROUND: Known causes of superficial punctuate keratopathy (SPK) in children include entropion, viral infection, blepharokeratoconjunctivitis (BKC), and toxicity of eye drops. However, there are some SPK patients whose causes could not be identified well. Herein, we describe the history, diagnosis, treatment, and prognosis of a rare case. CASE PRESENTATION: To report a case of superficial punctate keratopathy (SPK) which coexisted with floppy eyelid syndrome (FES) and presented as intermittent red eye and blurred vision in an 11-year-old boy who slept in the prone position...
February 23, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29447897/pattern-of-allergic-rhinitis-among-children-in-ekiti-nigeria
#10
Waheed Atilade Adegbiji, Gabriel Toye Olajide, Anthony Oyebanji Olajuyin, Shuaib Kayode Aremu, Akanbi Ganiyu Olusola
BACKGROUND: Allergic rhinitis is a chronic and recurrent nasal condition. It is often neglected in children with late presentation. This study aimed at determining the prevalence, sociodemographic features, comorbid illnesses, complications and quality of life in children with allergic rhinitis in the study institution. MATERIALS AND METHODS: This is a prospective hospital based study of children with allergic rhinitis in Ekiti state university teaching hospital, Ado Ekiti...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447802/effects-of-maxillary-protraction-appliances-on-airway-dimensions-in-growing-class-iii-maxillary-retrognathic-patients-a-systematic-review-and-meta-analysis
#11
REVIEW
Ye Ming, Yun Hu, Yuyue Li, Jinfeng Yu, Haojue He, Leilei Zheng
OBJECTIVES: The purpose of this study was to assess, through a systematic review and meta-analysis, the efficacy of maxillary protraction appliances (MPAs) on improving pharyngeal airway dimensions in growing class III patients with maxillary retrognathism. METHODS: An electronic search in PubMed, Cochrane Library, Web of Science, and EMBASE was until September 2nd, 2017. The assessments of methodological quality of the selected articles were performed using the Newcastle-Ottawa Scale...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29423745/in-reply-to-commentary-to-endoscopic-and-clinical-benefits-of-hyaluronic-acid-in-children-with-chronic-adenoiditis-and-middle-ear-disease-by-zhengcai-lou
#12
S Torretta, P Marchisio, V Rinaldi, D Carioli, E Nazzari, L Pignataro
Some considerations will be expressed in consideration of the commentary previously published. In particular, we underline that no other medications were administered to the patients during the study period and any clinical evaluation was postponed in case of acute upper respiratory tract infection in the previous 14 days. We strongly advocate antibiotic treatment during any acute otitis media episode, and we agree that topically administered hyaluronic acid should be considered as a supporting treatment, "complementary to traditional therapies" in children with recurrent disease...
February 8, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29415685/gluten-free-diet-may-improve-obstructive-sleep-apnea-related-symptoms-in-children-with-celiac-disease
#13
Anat Yerushalmy-Feler, Riva Tauman, Ari Derowe, Eran Averbuch, Amir Ben-Tov, Yael Weintraub, Dror Weiner, Achiya Amir, Hadar Moran-Lev, Shlomi Cohen
BACKGROUND: Enlarged tonsils and adenoids are the major etiology of obstructive sleep apnea (OSA) in children. Lymphatic hyperplasia is common to both OSA and celiac disease. We aimed to investigate the effect of a gluten-free diet on OSA symptoms in children with celiac disease. METHODS: Children with celiac disease aged 2-18 years were prospectively recruited before the initiation of a gluten-free diet. Children with negative celiac serology who underwent gastrointestinal endoscopies for other indications served as controls...
February 7, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29369187/clinical-application-of-mri-respiratory-gating-technology-in-the-evaluation-of-children-with-obstructive-sleep-apnea-hypopnea-syndrome
#14
Guohui Zeng, Yaoshu Teng, Jin Zhu, Darong Zhu, Bin Yang, Linpin Hu, Manman Chen, Xiao Fu
The objective of the present study was to investigate the clinical application of magnetic resonance imaging (MRI)-respiratory gating technology for assessing illness severity in children with obstructive sleep apnea hypopnea syndrome (OSAHS).MRI-respiratory gating technology was used to scan the nasopharyngeal cavities of 51 children diagnosed with OSAHS during 6 respiratory phases. Correlations between the ratio of the area of the adenoid to the area of the nasopalatine pharyngeal cavity (Sa/Snp), with the main indexes of polysomnography (PSG), were analyzed...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29360088/the-adenoid-microbiome-in-recurrent-acute-otitis-media-and-obstructive-sleep-apnea
#15
Carolyn O Dirain, Rodrigo C Silva, William O Collins, Patrick J Antonelli
OBJECTIVE: To compare the microbial flora of adenoids from patients with recurrent acute otitis media (AOM) and patients with obstructive sleep apnea (OSA). MATERIALS AND METHODS: This study was prospective and controlled. Adenoids were obtained from children undergoing adenoidectomy for recurrent AOM (n=7) or OSA (n=13). Specimens were processed for total deoxyribonucleic acid (DNA) isolation. 16s DNA 454-pyrosequencing was performed on AOM (n=5) and OSA (n=5) specimens...
December 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29330826/antibody-response-to-polyomavirus-primary-infection-high-seroprevalence-of-merkel-cell-polyomavirus-and-lymphoid-tissue-involvement
#16
Carolina Cason, Lorenzo Monasta, Nunzia Zanotta, Giuseppina Campisciano, Iva Maestri, Massimo Tommasino, Michael Pawlita, Sonia Villani, Manola Comar, Serena Delbue
Human polyomaviruses (HPyVs) asymptomatically infect the human population establishing latency in the host, and their seroprevalence can reach 90% in healthy adults. Few studies have focused on the pediatric population, and there are no reports regarding the seroprevalence of all the newly isolated HPyVs among Italian children. Therefore, we investigated the frequency of serum antibodies against 12 PyVs in 182 immunocompetent children from Northeast Italy, by means of a multiplex antibody detection system. Additionally, secondary lymphoid tissues were collected to analyze the presence of HPyV DNA sequences using a specific real-time PCRs or PCRs...
January 12, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/29313145/evaluation-of-choroidal-thickness-in-children-with-adenoid-hypertrophy
#17
Taliye Cakabay, Selin Üstün Bezgin, Sadık Etka Bayramoglu, Nihat Sayin, Murat Kocyigit
OBJECTIVE: To assess choroidal thickness in children with adenoid hypertrophy versus normal controls using enhanced depth imaging optical coherence tomography (EDI-OCT). METHODS: Twenty-six children (left and right eyes, total 52 eyes), which were scheduled to adenoidectomy with severe adenoid hypertrophy and 26 age, sex and body mass index-matched healthy subjects (left and right eyes, total 52 eyes) were included in the study. Choroidal thicknesses (CT) were evaluated using enhanced depth imaging optical coherence tomography...
February 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29313115/-diagnosis-and-treatment-of-eustachian-tube-dysfunction
#18
S Schröder, J Ebmeyer
The Eustachian tube protects against secretion, germs and sound pressure from the nasopharynx, it acts as a drain, and serves pressure equalization in both directions so that the ear drum and sound-conducting apparatus can vibrate optimally. The incidence of Eustachian tube dysfunction in adults is about 1%, in children almost 40%. Symptoms are often unspecific. For diagnosis, the Eustachian tube score (ETS-5) can be used in patients with a perforated ear drum, and the ETS-7 score in patients with intact ear drum...
February 2018: HNO
https://www.readbyqxmd.com/read/29306232/evaluation-of-the-effects-of-montelukast-mometasone-furoate-and-combined-therapyon-adenoid-size-a-randomized-prospective-clinical-trial-with-objective-data
#19
Birgül Tuhanıoğlu, Sanem Okşan Erkan
Background/aim: The incidence of adenoid hypertrophy is 2%-3% in children. Adenoidectomy is a commonly performed procedure in children that may cause complications such as early or late bleeding (4%-5%), recurrence of adenoid tissue (10%-20%), and postoperative respiratory problems (27%). Therefore, medical therapy alternatives to adenoidectomy are important and must be tried before surgery. In this study, we investigated the efficacy of mometasone furoate, montelukast, and a combination of these drugs in pediatric patients with adenoid hypertrophy who were scheduled for reduction with medical therapy after not being recommended for surgery...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29287875/coblation-versus-microdebrider-in-pediatric-adenoidectomy
#20
RANDOMIZED CONTROLLED TRIAL
Chris Mularczyk, David L Walner, Katherine K Hamming
OBJECTIVE: To compare and contrast coblation and microdebrider with touch-up electrocautery (ME) for adenoidectomy in children. METHODS: Patients <18 years old undergoing adenoidectomy without tonsillectomy were selected for this prospective, single-blinded, randomized controlled trial. Participants were enrolled into one of two groups based on birth date: coblation or ME. The surgeons completed a standard survey about intraoperative factors for each method. Recovery nurses filled out a standardized survey postoperatively...
January 2018: International Journal of Pediatric Otorhinolaryngology
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