keyword
MENU ▼
Read by QxMD icon Read
search

AHLS

keyword
https://www.readbyqxmd.com/read/28820240/the-interaction-between-the-third-type-iii-domain-from-fibronectin-and-anastellin-involves-%C3%AE-strand-exchange
#1
Jessica M Stine, Gabriel J H Ahl, Casey Schlenker, Domnita-Valeria Rusnac, Klára Briknarová
Anastellin is a small recombinant fragment derived from the extracellular matrix protein fibronectin; it comprises the first type III (FN3) domain without the two N-terminal β-strands. It inhibits angiogenesis, tumor growth, and metastasis in mouse models and requires endogenous fibronectin for its in vivo anti-angiogenic activity. It binds to fibronectin in vitro and converts the soluble protein to insoluble fibrils that structurally and functionally resemble fibronectin fibrils deposited in the extracellular matrix by cells...
August 18, 2017: Biochemistry
https://www.readbyqxmd.com/read/28819178/curcumin-liposomes-interfere-with-quorum-sensing-system-of-aeromonas-sobria-and-in-silico-analysis
#2
Ting Ding, Tingting Li, Zhi Wang, Jianrong Li
Aeromonas sobria is opportunistic pathogen frequently found in environment and food. Interfering with its quorum sensing (QS) system could be a promising way to alleviate its virulence. In this study, curcumin liposomes were prepared and their characteristics like particle size, zeta potential, PDI (Polymey Disperse Index), encapsulation efficiency and loading capacity were measured. The quorum sensing inhibitory effect of curcumin liposomes under sub-MIC (Minimum Inhibitory Concentration) on siderophore production, swimming and swarming motility, extracellular proteases, biofilm formation and AHLs (N-acylhomoserine lactones) production of A...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28817812/the-mir-34a-bcl-2-pathway-contributes-to-auditory-cortex-neuron-apoptosis-in-age-related-hearing-loss
#3
Qiuhong Huang, Yongkang Ou, Hao Xiong, Haidi Yang, Zhigang Zhang, Suijun Chen, Yongyi Ye, Yiqing Zheng
HYPOTHESIS: The miR-34a/Bcl-2 signaling pathway may play a role in the mechanisms related to age-related hearing loss (AHL) in the auditory cortex. BACKGROUND: The auditory cortex plays a key role in the recognition and processing of complex sound. It is difficult to explain why patients with AHL have poor speech recognition, so increasing numbers of studies have focused on its central change. Although micro (mi)RNAs in the central nervous system have recently been increasingly reported to be associated with age-related diseases, the molecular mechanisms of AHL in the auditory cortex are not fully understood...
August 18, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28814755/membrane-fouling-induced-by-ahl-mediated-soluble-microbial-product-smp-formation-by-fouling-causing-bacteria-co-cultured-with-fouling-enhancing-bacteria
#4
So Ishizaki, Ryoichi Sugiyama, Satoshi Okabe
Membrane fouling still remains a major obstacle for wider applications of membrane bioreactor (MBR), which is mainly caused by soluble microbial products (SMP). Identification of key bacteria responsible for SMP production is essential for mitigation of membrane fouling. Here, we investigated the effect of microbial interaction on membrane fouling. We measured the membrane fouling potentials of 13 bacterial strains isolated from a pilot-scale MBR treating domestic wastewater when they were cultivated as single-culture and co-culture...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28802136/the-role-of-sulfate-in-aerobic-granular-sludge-process-for-emerging-sulfate-laden-wastewater-treatment
#5
Weiqi Xue, Tianwei Hao, Hamish R Mackey, Xiling Li, Richard C Chan, Guanghao Chen
Sulfate-rich wastewaters pose a major threat to mainstream wastewater treatment due to the unpreventable production of sulfide and associated shift in functional bacteria. Aerobic granular sludge could mitigate these challenges in view of its high tolerance and resilience against changes in various environmental conditions. This study aims to confirm the feasibility of aerobic granular sludge in the treatment of sulfate containing wastewater, investigate the impact of sulfate on nutrient removal and granulation, and reveal metabolic relationships in the above processes...
August 4, 2017: Water Research
https://www.readbyqxmd.com/read/28780591/revealing-strategies-of-quorum-sensing-in-azospirillum-brasilense-strains-ab-v5-and-ab-v6
#6
Josiane Fukami, Julia Laura Fernandes Abrantes, Pablo Del Cerro, Marco Antonio Nogueira, Francisco Javier Ollero, Manuel Megías, Mariangela Hungria
Azospirillum brasilense is an important plant-growth promoting bacterium (PGPB) that requires several critical steps for root colonization, including biofilm and exopolysaccharide (EPS) synthesis and cell motility. In several bacteria these mechanisms are mediated by quorum sensing (QS) systems that regulate the expression of specific genes mediated by the autoinducers N-acyl-homoserine lactones (AHLs). We investigated QS mechanisms in strains Ab-V5 and Ab-V6 of A. brasilense, which are broadly used in commercial inoculants in Brazil...
August 5, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28777091/the-quorum-quenching-lactonase-from-alicyclobacter-acidoterrestris-purification-kinetic-characterization-crystallization-and-crystallographic-analysis
#7
Celine Bergonzi, Michael Schwab, Eric Chabriere, Mikael Elias
Lactonases comprise a class of enzymes that hydrolyze lactones, including acyl-homoserine lactones (AHLs); the latter are used as chemical signaling molecules by numerous Gram-negative bacteria. Lactonases have therefore been demonstrated to quench AHL-based bacterial communication. In particular, lactonases are capable of inhibiting bacterial behaviors that depend on these chemicals, such as the formation of biofilms or the expression of virulence factors. A novel representative from the metallo-β-lactamase superfamily, named AaL, was isolated from the thermoacidophilic bacterium Alicyclobacter acidoterrestris...
August 1, 2017: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/28765541/in-silico-analyses-of-conservational-functional-and-phylogenetic-distribution-of-the-luxi-and-luxr-homologs-in-gram-positive-bacteria
#8
Akanksha Rajput, Manoj Kumar
LuxI and LuxR are key factors that drive quorum sensing (QS) in bacteria through secretion and perception of the signaling molecules e.g. N-Acyl homoserine lactones (AHLs). The role of these proteins is well established in Gram-negative bacteria for intercellular communication but remain under-explored in Gram-positive bacteria where QS peptides are majorly responsible for cell-to-cell communication. Therefore, in the present study, we explored conservation, potential function, topological arrangements and evolutionarily aspects of these proteins in Gram-positive bacteria...
August 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28762063/the-first-report-on-listeria-monocytogenes-producing-siderophores-and-responds-positively-to-n-acyl-homoserine-lactone-ahl-molecules-by-enhanced-biofilm-formation
#9
Milind Mohan Naik, Purva Bhangui, Chinmay Bhat
Listeria monocytogenes are Gram-positive well-known emerging food-borne pathogens causing listeriosis in humans. In the present study, we have isolated biofilm-forming Listeria sp. from utensils used by a local milk collection dairy society at Usgao Goa, which collects milk for Goa dairy. Through biochemical tests and 16S rRNA sequence analysis, the bacterium was confirmed to be L. monocytogenes and designated as strain BN3, having GenBank accession number MF095110. We report for the first time Gram-positive L...
July 31, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28756190/mir-34a-bcl-2-signaling-pathway-contributes-to-age-related-hearing-loss-by-modulating-hair-cell-apoptosis
#10
Qiuhong Huang, Yiqing Zheng, Yongkang Ou, Hao Xiong, Haidi Yang, Zhigang Zhang, Suijun Chen, Yongyi Ye
MicroRNAs, such as miR-34, have been reported to influence age-related diseases. In this study, we explored the role of the miR-34a/Bcl-2 signaling pathway in age-related hearing loss (AHL). Using an AHL mouse model (C57BL/6), we found that the expression of miR-34a in the cochlea increased with age, whereas expression of Bcl-2 decreased. Increasing the amount of a miR-34a mimetic in a mouse auditory cell line (HEI-OC1) inhibited Bcl-2, leading to enhanced apoptosis; in contrast, miR-34a inhibition produced the opposite effect...
July 26, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28746399/coordination-of-matrix-attachment-and-atp-dependent-chromatin-remodeling-regulate-auxin-biosynthesis-and-arabidopsis-hypocotyl-elongation
#11
Kyounghee Lee, Pil Joon Seo
Hypocotyl elongation is extensively controlled by hormone signaling networks. In particular, auxin metabolism and signaling play key roles in light-dependent hypocotyl growth. The nuclear matrix facilitates organization of DNA within the nucleus, and dynamic interactions between nuclear matrix and DNA are related to gene regulation. Conserved scaffold/matrix attachment regions (S/MARs) are anchored to the nuclear matrix by the AT-HOOK MOTIF CONTAINING NUCLEAR LOCALIZED (AHL) proteins in Arabidopsis. Here, we found that ESCAROLA (ESC)/AHL27 and SUPPRESSOR OF PHYTOCHROME B-4 #3 (SOB3)/AHL29 redundantly regulate auxin biosynthesis in the control of hypocotyl elongation...
2017: PloS One
https://www.readbyqxmd.com/read/28711170/early-selenium-treatment-for-traumatic-brain-injury-does-it-improve-survival-and-functional-outcome
#12
Hosseinali Khalili, Rebecka Ahl, Yang Cao, Shahram Paydar, Gabriel Sjölin, Amin Niakan, Gholamreza Dabiri, Shahin Mohseni
BACKGROUND: Traumatic brain injury (TBI) is a major cause of death and debility following trauma. The initial brain tissue insult is worsened by secondary reactive responses including oxidative stress reactions, inflammatory changes and subsequent permanent neurologic deficits. Effective agents to improve functional outcome and survival following TBI are scarce. Selenium is an antioxidant which has shown to reduce oxidative stress. This study examines the effect of intravenous selenium (Selenase(®)) treatment in patients with severe TBI on functional outcome and survival in a prospective study design...
July 8, 2017: Injury
https://www.readbyqxmd.com/read/28706380/importance-of-anterior-humeral-line-for-successful-anatomical-reduction-in-the-surgical-treatment-of-pediatric-supracondylar-humeral-fractures
#13
Takamasa Shimizu, Atsushi Yoshida, Shohei Omokawa, Tadanobu Onishi, Tsutomu Kira, Shigeru Santo, Hideo Hasewgawa, Kenji Kawamura, Yasuhito Tanaka
Anterior humeral line (AHL) and tilting angle (TA) are used for the assessment of pediatric elbow sagittal plane alignment in surgical treatment of pediatric supracondylar humeral fracture. However, few studies exist that compare the reliabilities between these parameters. The purpose of this study is to determine whether measurements of radiographic parameters are reliable and useful for achieving anatomical reduction. In the current study, we demonstrated that the identifying the AHL location involves a simple and reliable measurement compared with TA...
September 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28702008/hypersensitive-response-of-plasmid-encoded-ahl-synthase-gene-to-lifestyle-and-nutrient-by-ensifer-adhaerens-x097
#14
Yanhua Zeng, Yanli Wang, Zhiliang Yu, Yili Huang
It is known that some bacteria, especially members of the family Rhizobiaceae, have multiple N-acyl homoserine lactones (AHL) synthase genes and produce multiple AHL signals. However, how bacteria selectively utilize these multiple genes and signals to cope with changing environments is poorly understood. Ensifer adhaerens is an important microorganism in terms of biotechnology, ecology and evolutionary. In this study, we investigated the AHL-based QS system of E. adhaerens X097 and its response to different lifestyles or nutrients...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28701854/is-linguistic-injustice-a-myth-a-response-to-hyland-2016
#15
Stephen Politzer-Ahles, Jeffrey J Holliday, Teresa Girolamo, Maria Spychalska, Kelly Harper Berkson
No abstract text is available yet for this article.
December 2016: J Second Lang Writ
https://www.readbyqxmd.com/read/28697551/n-acyl-homoserine-lactone-dynamics-during-biofilm-formation-of-a-1-2-4-trichlorobenzene-mineralizing-community-on-clay
#16
Hongjie Sheng, Mourad Harir, Lisa A Boughner, Xin Jiang, Philippe Schmitt-Kopplin, Reiner Schroll, Fang Wang
In Gram-negative bacteria, quorum sensing systems are based on the N-acyl-homoserine lactone (AHL) molecule. The objective of this study was to investigate the role of quorum sensing systems during biofilm formation by a microbial community while degrading the pollutant. Our model system included 1,2,4-trichlorobenzene (1,2,4-TCB) and its mineralizing Gram-negative bacterial community to investigate the relationships between AHL dynamics, cell growth and pollutant degradation. Biomineralization of 1,2,4-TCB was monitored for both the planktonic bacterial community with and without sterile clay particles in liquid cultures...
July 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28695853/crystal-structure-of-the-n-terminal-domain-of-vqsr-from-pseudomonas-aeruginosa-at-2-1%C3%A2-%C3%A3-resolution
#17
Qing He, Kang Wang, Tiantian Su, Feng Wang, Lichuan Gu, Sujuan Xu
VqsR is a quorum-sensing (QS) transcriptional regulator which controls QS systems (las, rhl and pqs) by directly downregulating the expression of qscR in Pseudomonas aeruginosa. As a member of the LuxR family of proteins, VqsR shares the common motif of a helix-turn-helix (HTH)-type DNA-binding domain at the C-terminus, while the function of its N-terminal domain remains obscure. Here, the crystal structure of the N-terminal domain of VqsR (VqsR-N; residues 1-193) was determined at a resolution of 2.1 Å...
July 1, 2017: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/28690598/large-diversity-and-original-structures-of-acyl-homoserine-lactones-in-strain-mola-401-a-marine-rhodobacteraceae-bacterium
#18
Margot Doberva, Didier Stien, Jonathan Sorres, Nathalie Hue, Sophie Sanchez-Ferandin, Véronique Eparvier, Yoan Ferandin, Philippe Lebaron, Raphaël Lami
Quorum sensing (QS) is a density-dependent mechanism allowing bacteria to synchronize their physiological activities, mediated by a wide range of signaling molecules including N-acyl-homoserine lactones (AHLs). Production of AHL has been identified in various marine strains of Proteobacteria. However, the chemical diversity of these molecules still needs to be further explored. In this study, we examined the diversity of AHLs produced by strain MOLA 401, a marine Alphaproteobacterium that belongs to the ubiquitous Rhodobacteraceae family...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28688010/quorum-sensing-molecules-production-by-nosocomial-and-soil-isolates-acinetobacter-baumannii
#19
Demet Erdönmez, Abbas Yousefi Rad, Nilüfer Aksöz
Acinetobacter species remain alive in hospitals on various surfaces, both dry and moist, forming an important source of hospital infections. These bacteria are naturally resistant to many antibiotic classes. Although the role of the quorum sensing system in regulating the virulence factors of Acinetobacter species has not been fully elucidated, it has been reported that they play a role in bacterial biofilm formation. The biofilm formation helps them to survive under unfavorable growth conditions and antimicrobial treatments...
July 7, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28687817/etiologic-and-audiologic-characteristics-of-patients-with-pediatric-onset-unilateral-and-asymmetric-sensorineural-hearing-loss
#20
Pei-Hsuan Lin, Chuan-Jen Hsu, Yi-Hsin Lin, Yin-Hung Lin, Hui-Yu Lee, Chen-Chi Wu, Tien-Chen Liu
Importance: Pediatric-onset unilateral and asymmetric sensorineural hearing loss (SNHL) is a common condition, but in most patients, the cause remains unclear; thus, determination of the hearing outlook is difficult. Objective: To analyze the etiologic and audiologic characteristics of pediatric-onset unilateral and asymmetric SNHL. Design, Setting, and Participants: In this retrospective cohort study performed from January 1, 2008, through December 31, 2016, patients at a tertiary referral center who were diagnosed with pediatric-onset unilateral or asymmetric SNHL were divided into 3 groups according to their hearing levels: unilateral hearing loss with scaled-out levels (UHL-SO), unilateral hearing loss with residual hearing (UHL-RH), and asymmetric hearing loss (AHL)...
July 6, 2017: JAMA Otolaryngology—Head & Neck Surgery
keyword
keyword
119067
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"