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Caustic esophagitis

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https://www.readbyqxmd.com/read/28533917/management-of-esophageal-caustic-injury
#1
EDITORIAL
Mark Anthony A De Lusong, Aeden Bernice G Timbol, Danny Joseph S Tuazon
Ingestion of caustic substances and its long-term effect on the gastrointestinal system maintain its place as an important public health issue in spite of the multiple efforts to educate the public and contain its growing number. This is due to the ready availability of caustic agents and the loose regulatory control on its production. Substances with extremes of pH are very corrosive and can create severe injury in the upper gastrointestinal tract. The severity of injury depends on several aspects: Concentration of the substance, amount ingested, length of time of tissue contact, and pH of the agent...
May 6, 2017: World Journal of Gastrointestinal Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28533657/esophagitis-and-its-causes-who-is-guilty-when-acid-is-found-not-guilty
#2
EDITORIAL
Laurino Grossi, Antonio Francesco Ciccaglione, Leonardo Marzio
Esophagitis is mainly a consequence of gastroesophageal reflux disease, one of the most common diseases affecting the upper digestive tract. However the esophageal mucosa can also be targeted by some infectious, systemic or chemical conditions. Eosinophilic esophagitis (EoE) is an immune-mediated inflammatory disease, characterized by eosinophilic infiltration in the mucosa. Esophageal localization of Crohn's disease is not very common, but it should always be considered in patients with inflammatory bowel disease complaining of upper digestive tract symptoms...
May 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28523486/esophagectomy-with-esophagocoloplasty-for-malignancies-indications-technique-with-video-and-results-systematic-review-of-the-literature
#3
Paolo Aurello, Niccolo' Petrucciani, Dario Sirimarco, Livia Maria Mangogna, Giuseppe Nigri, Stefano Valabrega, Francesco D'Angelo, Giovanni Ramacciato
INTRODUCTION: Esophagocoloplasty represents a useful technique to restore the intestinal continuity after esophagogastrectomy. This technique has been used mainly after esophagogastric caustic injuries. The aim of this review is to assess the role of esophagogastrectomy with esophagocoloplasty for esophageal or gastric neoplasms. METHODS: A systematic literature search was performed using Embase, Medline, Cochrane, and PubMed databases to identify all studies published in the previous 25 years (1991-2016) reporting cases of esophagocoloplasty after esophagogastrectomy for malignancies...
May 18, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28492712/lugol-s-iodine-chromoendoscopy-versus-narrow-band-image-enhanced-endoscopy-for-the-detection-of-esophageal-cancer-in-patients-with-stenosis-secondary-to-caustic-corrosive-agent-ingestion
#4
Caterina Maria Pia Simoni Pennachi, Diogo Turiani Hourneaux de Moura, Renato Bastos Pimenta Amorim, Hugo Gonçalo Guedes, Vivek Kumbhari, Eduardo Guimarães Hourneaux de Moura
BACKGROUND: The diagnosis of corrosion cancer should be suspected in patients with corrosive ingestion if after a latent period of negligible symptoms there is development of dysphagia, or poor response to dilatation, or if respiratory symptoms develop in an otherwise stable patient of esophageal stenosis. Narrow Band Imaging detects superficial squamous cell carcinoma more frequently than white-light imaging, and has significantly higher sensitivity and accuracy compared with white-light...
May 8, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28489832/caustic-ingestion-in-children-in-south-of-iran-retrospective-study-from-shiraz-iran
#5
Naser Honar, Mahmood Haghighat, Samaneh Mahmoodi, Hazhir Javaherizadeh, Gholamreza Kalvandi, Mohammad Salimi
Caustic ingestion is a major health concern in both developed and developing countries, that may lead to serious esophageal injury. The clinical presentation of caustic ingestion in children vary from asymptomatic to serious and fatal sequelae, such as perforation and stricture formation. OBJECTIVE: Due to the lack of a comprehensive study in our area, this study has evaluated clinical and endoscopic manifestations and complications of caustic ingestion in children in south of Iran. MATERIALS AND METHODS: In this retrospective study, we reviewed 75 children with caustic ingestion who admitted in Nemazee Hospital of Shiraz University of Medical Science during 6 years (2006-2011)...
January 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28472833/relook-endoscopy-predicts-the-development-of-esophageal-and-antropyloric-stenosis-better-than-immediate-endoscopy-in-patients-with-caustic-ingestion
#6
Rakesh Kochhar, Munish Ashat, Yalaka Rami Reddy, Narender Dhaka, Manish Manrai, Saroj K Sinha, Usha Dutta, Thakur D Yadav, Vikas Gupta
Background and aims Early ( < 24 hours) esophagogastroduodenoscopy (EGD) is used to prognosticate mucosal injury after caustic ingestion. We aimed to compare differences in endoscopic grading on EGDs performed on day 5 and day 1 and to assess the impact of relook endoscopy findings on the development of esophageal and/or antropyloric cicatrization. Patients and methods Consecutive patients admitted within 24 hours of caustic ingestion between 2009 and 2014 underwent EGD and had their mucosal changes graded...
May 4, 2017: Endoscopy
https://www.readbyqxmd.com/read/28451845/reflux-esophagitis-and-its-role-in-the-pathogenesis-of-barrett-s-metaplasia
#7
REVIEW
Rhonda Frances Souza
Reflux esophagitis damages the squamous epithelium that normally lines the esophagus, and promotes replacement of the damaged squamous lining by the intestinal metaplasia of Barrett's esophagus, the precursor of esophageal adenocarcinoma. Therefore, to prevent the development of Barrett's metaplasia and esophageal adenocarcinoma, the pathogenesis of reflux esophagitis must be understood. We have reported that reflux esophagitis, both in a rat model and in humans, develops as a cytokine-mediated inflammatory injury (i...
April 27, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/28447968/protective-effects-of-ursodeoxycholic-acid-in-experimental-corrosive-esophagitis-injury-in-rats
#8
Adem Ku Çu K, Naci Topaloglu, Sule Yildirim, Mustafa Tekin, Mesut Erbas, Hasan Ali Kiraz, Havva Erdem, Aybars Özkan
Accidental caustic ingestions are serious medical problems especially in childhood. Various treatment modalities are being used for the complications of caustic injuries such as stricture formation. The aim of this study is to establish whether ursodeoxycholic acid (UDCA) has protective effects on experimental corrosive esophagitis in rats. Twenty four Wistar-albino rats, weighing 220-240 g, were used in the study. Experimental animals were divided in three groups randomly: UDCA treatment group (Group T, n:8), control group (Group K, n: 8) and sham group (Group S, n: 8)...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28444489/biodegradable-stents-for-caustic-esophageal-strictures-do-they-work
#9
Rakesh Kochhar, Jayanta Samanta, Jahangeer Basha, Abhai Verma, Gourdas Choudhuri, Sundeep Lakhtakia, D Nageshwar Reddy
Biodegradable (BD) stents have been used for the management of various esophageal strictures (ES) but the experience of its use in caustic strictures is limited. The present study, aimed at evaluating efficacy of BD stents for the treatment of refractory caustic-induced ES, was a retrospective multi-center study conducted at three tertiary care centers in India wherein adult patients with refractory caustic induced strictures underwent placement of a BD stent. Patients were followed up for immediate complications and long term outcome...
April 25, 2017: Dysphagia
https://www.readbyqxmd.com/read/28439202/a-rare-complication-of-esophageal-dilatation-brain-abscess
#10
Nagehan Aslan, Esra Sesli, Tuba Koca, Nilgün Şenol, Mustafa Akçam
Brain abscess is an uncommon serious disease, which has been reported as a rare complication of repeated esophageal dilations; however, routine periprocedural antibiotic prophylaxis is not currently recommended. Herein, we present a brain abscess that developed after esophageal dilatation for the treatment of induced caustic esophageal strictures. The clinical presentation is non-specific, the most reported signs are high fever and neurologic findings. Cases have been reported in the literature in adult and pediatric patients...
March 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28371514/bi-layer-silk-fibroin-grafts-support-functional-esophageal-repair-in-a-rodent-model-of-caustic-injury
#11
Khalid Algarrahi, Debra Franck, Alyssa Savarino, Vivian Cristofaro, Xuehui Yang, Saif Affas, Frank-Mattias Schäfer, Maryrose P Sullivan, Carlos R Estrada, Joshua R Mauney
Surgical repair of caustic esophageal injuries with autologous gastrointestinal segments is often associated with dysmotility, dysphagia, and donor site morbidity and therefore alternative graft options are needed. Bi-layer silk fibroin (BLSF) scaffolds were assessed for their ability to support functional restoration of damaged esophageal tissues in a rat model of onlay esophagoplasty. Transient exposure of isolated esophageal segments with 40% NaOH led to corrosive esophagitis and a 91% reduction in the luminal cross-sectional area of damaged sites...
March 30, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28343609/very-late-onset-dabigatran-induced-esophageal-injury
#12
Ko Fujikawa, Nobuhiro Takasugi, Tadao Goto, Shinya Minatoguchi
An 87-year-old man with persistent atrial fibrillation experienced heartburn and dysphagia at 2 years 9 months after initiation of dabigatran. An esophagogastroduodenoscopy demonstrated multiple longitudinal white plaques with ulcers in the narrowed midesophagus compressed between the left atrium and the tortuous aorta. We speculate that the esophageal stenosis contributed to stasis of dabigatran within the esophagus, resulting in prolonged mucosal contact with the caustic contents of the drug. Progressive enlargement of the left atrium may have led to the late onset of the potentially serious complication...
April 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28340493/conservative-treatment-with-octreotide-to-provide-early-recovery-of-children-with-esophageal-perforation
#13
Ramazan Karabulut, Zafer Turkyilmaz, Kaan Sonmez, Abdullah Can Basaklar
Background The effectiveness of nonoperative treatment of esophageal perforation (EP) in children with octreotide is highlighted. Methods Records of nine patients (seven boys and two girls with an average age of 5.83 ± 5.35 years) with EP were reviewed. Results EP developed in six patients during dilation of esophageal stenosis (five of six caused by caustic burns). In the other three patients, EP developed after nasogastric placement, after endotracheal intubation, and during endoscopy for foreign body...
March 24, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28318189/evaluation-of-esophageal-injuries-secondary-to-ingestion-of-unlabeled-corrosive-substances-pediatric-case-series
#14
Gonul Kucuk, Gulnur Gollu, Ufuk Ates, Zeynep A Cakmak, Meltem Kologlu, Aydın Yagmurlu, Tanju Aktug, Huseyin Dindar, Ahmet M Cakmak
Esophageal or gastric injuries secondary to caustic substance ingestion is still an important issue in developing countries. Its clinical spectrum can vary from absence of mucosal injury to complications such as severe burns, strictures and perforation. Physical examination and first endoscopic evaluation are very important in the diagnosis. The objective of this study is to present 154 children who were undergone upper gastrointestinal endoscopy because of caustic substance ingestion including descaler, degreaser, unlabeled bleach, drain opener, surface cleaner, dishwasher rinse aid, hydrochloric acid...
April 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28281403/effectiveness-of-endoscopic-balloon-dilatation-in-grade-2a-and-2b-esophageal-burns-in-children
#15
Hakan Taşkinlar, Gökhan Berktuğ Bahadir, Doğakan Yiğit, Cankat Erdoğan, Dinçer Avlan, Ali Nayci
PURPOSE: To evaluate the predictability of the initial endoscopic evaluation of the effectiveness of endoscopic balloon dilatation (EBD) in childhood esophageal strictures caused by corrosive ingestion. MATERIAL AND METHODS: Medical records of 635 endoscopies caused by corrosive ingestion between January 2000 and December 2015 in children between the ages of 0 and 18 years were retrospectively analyzed. Among them, five children with grade 2a and 15 with grade 2 b who developed esophageal strictures were evaluated for the effectiveness of endoscopic balloon dilatation...
March 10, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28216076/total-esophageal-substitution-for-combined-hypopharyngeal-and-esophageal-strictures-after-corrosive-injury-in-children
#16
Ana Cristina Aoun Tannuri, Uenis Tannuri
BACKGROUND/PURPOSE: The treatment of children with esophageal strictures and involvement of the hypopharynx caused by caustic substance ingestion continues to be challenging. The aims of the present study are to describe the peculiarities of the technique of complete esophageal substitution for the treatment of children with severe caustic strictures (pharyngocoloplasties) and to compare the results to those of classical esophagocoloplasty with thoracic and abdominal esophageal substitution in another group of children...
February 12, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28191325/management-of-esophageal-burns-caused-by-caustic-ingestion-a-case-report
#17
Bita Shahbazzadegan, Mehdi Samadzadeh, Iraj Feizi, Yousef Shafaiee
INTRODUCTION: Domestic and industrial swallowing of caustic substances can cause acute and chronic injuries. In the acute phase of care, focus is on the immediate control of tissue damage and perforation, and in the chronic phase, the focus is on the treatment of pharyngeal narrowing and impaired swallowing. CASE PRESENTATION: The patients of this report were an 18-year-old man and a 20-year-old woman, who had esophageal burns after ingesting chemicals, and for solving their nutritional problems, such as difficulty in swallowing, they had underwent surgery...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28144066/erosion-of-esophageal-stent-into-left-main-bronchus-causing-airway-compromise
#18
S Aneeshkumar, L Sundararajan, Rajan Santosham, Rajkumar Palaniappan, Ubal Dhus
Covered or uncovered self-expanding metal stents are currently used for the palliative treatment of neoplastic esophageal strictures or compressions and esophageal leaks or fistulas due to malignancies. Erosion of esophageal stents into the respiratory tract is a rare complication and that too has been reported mostly as an early complication within few days or weeks. Here, we present the case of a 31-year-old female, who presented with a late complication of an esophageal stent eroding into the left main bronchus causing respiratory distress...
January 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28066602/a-novel-surgical-method-for-acquired-non-malignant-complicated-tracheoesophageal-and-bronchial-gastric-stump-fistula-the-double-patch-technique
#19
Guang Yang, Wei-Miao Li, Jin-Bo Zhao, Jian Wang, Yun-Feng Ni, Yong-An Zhou, Yong Han, Xiao-Fei Li, Xiao-Long Yan
BACKGROUND: To manage the acquired benign complicated tracheoesophageal fistula (TEF) and bronchial-gastric stump fistula (BGSF) are clinical technical challenge. The purpose of this study is to retrospectively review a surgical "double patch" technique in treating nonmalignant complicated TEF and BGSF, and then clarify the long-term curative effect of the technique. METHODS: Clinical records of 30 patients with non-malignant complicated TEF and BGSF treated by "double patch" technique in Tangdu Hospital between August 2004 and August 2014, were analyzed and summarized retrospectively...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28063680/gastric-tube-esophagoplasty-for-pediatric-esophageal-replacement
#20
Mahmoud M A Elfiky, Gamal El Tagy, Wissam Mohamed, Osama Abdel Azim, Mohamed A Elfiky
BACKGROUND: Esophageal replacement in children is indicated in cases of esophageal atresia with or without fistula, in case of long gap esophageal atresia or failed primary repair. Intractable post corrosive esophageal stricture is considered also a major indication for replacement. METHODS: This is a cohort retrospective study of esophageal replacement cases by gastric tube carried out at the pediatric surgery department at Cairo University between 2011 and 2015...
April 2017: Journal of Pediatric Surgery
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