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Trend on pms

Lieke G E M Razenberg, Valery E P P Lemmens, Victor J Verwaal, Cornelis J A Punt, Pieter J Tanis, Geert-Jan Creemers, Ignace H J T de Hingh
PURPOSE: To determine the impact of the implementation of novel systemic regimens and locoregional treatment modalities on survival at population level in colorectal cancer (CRC) patients presenting with peritoneal metastases (PMs). METHODS: All consecutive CRC patients with synchronous PM (<3 months) between 1995 and 2014 were extracted from the Eindhoven area of the Netherlands Cancer Registry. Trends in treatment and overall survival were assessed in four time periods...
September 2016: European Journal of Cancer
Eldon Y Li, Chen-Yuan Tung, Shu-Hsun Chang
BACKGROUND: The quest for an effective system capable of monitoring and predicting the trends of epidemic diseases is a critical issue for communities worldwide. With the prevalence of Internet access, more and more researchers today are using data from both search engines and social media to improve the prediction accuracy. In particular, a prediction market system (PMS) exploits the wisdom of crowds on the Internet to effectively accomplish relatively high accuracy. OBJECTIVE: This study presents the architecture of a PMS and demonstrates the matching mechanism of logarithmic market scoring rules...
August 2016: International Journal of Medical Informatics
Nycole A Copping, Elizabeth L Berg, Gillian M Foley, Melanie D Schaffler, Beth L Onaga, Nathalie Buscher, Jill L Silverman, Mu Yang
SHANK3 is a synaptic scaffolding protein localized in the postsynaptic density and has a crucial role in synaptogenesis and neural physiology. Deletions and point mutations in SHANK3 cause Phelan-McDermid Syndrome (PMS), and have also been implicated in autism spectrum disorder (ASD) and intellectual disabilities, leading to the hypothesis that reduced SHANK3 expression impairs basic brain functions that are important for social communication and cognition. Several mouse models of Shank3 deletions have been generated, varying in the specific domain deleted...
May 14, 2016: Neuroscience
Niraj Kumar Singh, Chithra Sobha Sasidharan
Listening to music through a portable personal music system (PMS) is a growing trend, especially among the youth. The preferred listening level in such kinds of PMS has been reported to cross the safe levels and its impact on the auditory system was demonstrated in several previous investigations. Owing to the commonality in several aspects between the auditory and the vestibular systems, it appears likely that the deleterious effects of PMS use could also be impinging on the vestibular system, which has never been investigated...
March 2016: Noise & Health
J Endrikat, C Schwenke, M R Prince
AIM: To assess the safety of gadobutrol administration in elderly patients (≥65 years) by comparing the incidence of adverse drug reactions (ADRs) following gadobutrol-enhanced magnetic resonance imaging (MRI) procedures in elderly patients with that in adults aged 18-64 years. MATERIALS AND METHODS: Safety data on gadobutrol administration from clinical trials, post-marketing surveillance (PMS) studies, and pharmacovigilance reports were collected in three databases...
July 2015: Clinical Radiology
Sakthivel Thangavel, Nivea Raghavan, Govindan Kadarkarai, Sang-Jae Kim, Gunasekaran Venugopal
This work demonstrates the preparation of graphene-oxide (GO)-Fe(3+) hybrids nanosheets and their high bleaching efficiency on the dye "Reactive Red 120 (RR 120)" by using sonocatalytic degradation. Sonocatalytic degradation was enhanced by using oxidants like PMS (peroxomonosulphate), PDS (peroxodisulphate), H2O2 (hydrogen peroxide) and KIO4 (potassium periodate). Our observations manifested that the degradation of the dye "RR 120" was found to be multiplied by addition of oxidants in the order of PMS>H2O2>PDS>KIO4...
May 2015: Ultrasonics Sonochemistry
Hisashi Yamanaka, Masayoshi Harigai, Naoki Ishiguro, Shigeko Inokuma, Syuji Takei, Tsutomu Takeuchi, Yoshiya Tanaka, Haruko Suzuki, Yasuhiko Shinmura, Takao Koike
OBJECTIVES: To investigate the relationship between changes in patient characteristics over time and the effectiveness and safety of adalimumab in the treatment of rheumatoid arthritis (RA) in clinical practice. METHODS: Patients enrolled in the post-marketing registry study in Japan were divided into 5 subgroups based on the time adalimumab treatment was initiated. Demographic and baseline characteristics and responses to adalimumab were compared among the 5 subgroups to detect any time-course trend...
July 2015: Modern Rheumatology
Ryohei Kaseda, Kathy Jabs, Tracy E Hunley, Deborah Jones, Aihua Bian, Ryan M Allen, Kasey C Vickers, Patricia G Yancey, MacRae F Linton, Sergio Fazio, Valentina Kon
OBJECTIVES: Our aim was to determine if chronic kidney disease (CKD) occurring in childhood impairs the normally vasoprotective functions of high-density lipoproteins (HDLs). MATERIALS AND METHODS: HDLs were isolated from children with end-stage renal disease on dialysis (ESRD), children with moderate CKD and controls with normal kidney function. Macrophage response to HDLs was studied as expression of inflammatory markers (MCP-1, TNF-α, IL-1β) and chemotaxis...
February 2015: Metabolism: Clinical and Experimental
Rui Diogo, Janine M Ziermann, Marta Linde-Medina
William K. Gregory was one of the most influential authors defending the existence of an evolutionary trend in vertebrates from a higher degree of polyisomerism (more polyisomeric or 'serial' anatomical structures arranged along any body axis) to cases of anisomerism (specialization or loss of at least some original polyisomeric structures). Anisomerism was the subject of much interest during the 19th and the beginning of the 20th centuries, particularly due to the influence of the Romantic German School and the notion of 'primitive archetype' and because it was conceptually linked to other crucial biological issues (e...
August 2015: Biological Reviews of the Cambridge Philosophical Society
Direkvand-Moghadam A, Sayehmiri K, Delpisheh A, Kaikhavandi Sattar
BACKGROUND AND OBJECTIVES: Premenstrual Syndrome (PMS) is a common health problem in women in reproductive age. The present study aimed to investigate the prevalence of PMS using meta-analysis method. METHODS: This meta-analysis systematically reviewed the prevalence of PMS. A search was conducted using keywords Premenstrual Syndrome, PMS, prevalence PMS and symptom of PMS in reliable English articles. The initial search 53 articles were available. After review of full-text articles, 17 articles were selected for analysis...
February 2014: Journal of Clinical and Diagnostic Research: JCDR
Soma Saha, Ravinder Goswami
BACKGROUND: Some of the patients with idiopathic hypoparathyroidism (IHP) report symptoms of hypocalcemia during menstruation. There is limited data on this observation. METHODS: Twenty six menstruating women with IHP and 26 healthy controls were questioned regarding symptoms suggestive of hypocalcemia during menstruation. Twelve patients and eight controls were asked to prospectively monitor symptoms suggestive of hypocalcemia and premenstrual syndrome (PMS) if any, over two consecutive menstrual cycles...
2014: BMC Endocrine Disorders
S Ann Hartlage, Cynthia A Breaux, Kimberly A Yonkers
OBJECTIVE: Inclusion of premenstrual dysphoric disorder (PMDD) into the main text of the DSM has been a point of controversy for many years. The purpose of this article is to address the main concerns raised by opponents to its inclusion. Concerns are presented and countered in turn. LITERATURE SEARCH: To identify the most prevalent arguments against inclusion of PMDD, we searched MEDLINE (1966-2012), PsycINFO (1930-2012), the Internet, and reference lists of identified articles during September 1-17, 2012, using the keywords PMDD, premenstrual syndrome (PMS), DSM, DSM-5, concerns, controversy, women, political power, workforce, courts, and history...
January 2014: Journal of Clinical Psychiatry
Hongzhen Yu, Dengning Xia, Quanlei Zhu, Chunliu Zhu, Dan Chen, Yong Gan
Polymeric micelles provide a promising platform for improving oral absorption of poorly soluble drugs. However, improved understanding of how drug retention within the hydrophobic micelle core can reduce drug absorption is required. We designed supersaturated polymeric micelles (Super-PMs) to increase molecularly dissolved drug concentration and gain an insight into the effect of the degree of supersaturation on oral absorption of cyclosporine A (CsA) in rats. The drug release from Super-PMs increased with an increase in initial supersaturation degrees in micelles...
November 2013: European Journal of Pharmaceutics and Biopharmaceutics
Stefan Schneider, Joan E Broderick, Doerte U Junghaenel, Joseph E Schwartz, Arthur A Stone
OBJECTIVE: Patient-reported outcome measures with reporting periods of a week or more are often used to evaluate the change of symptoms over time, but the accuracy of recall in the context of change is not well understood. This study examined whether temporal trends in symptoms that occur during the reporting period impact the accuracy of 7-day recall reports. METHODS: Women with premenstrual symptoms (n=95) completed daily reports of anger, depression, fatigue, and pain intensity for 4weeks, as well as 7-day recall reports at the end of each week...
August 2013: Journal of Psychosomatic Research
Olle Eriksson, Mikael Landén, Charlotta Sundblad, Jan Holte, Elias Eriksson, Tord Naessén
Ovarian cyclicity is a prerequisite for premenstrual dysphoria (PMD), as illustrated by the fact that this condition is effectively eliminated by ovariectomy or by treatment with a GnRH agonist. Despite the possibility of differences in ovarian function between women with and without PMD, no study comparing ovarian morphology in these two groups has ever been published. Fifty-two women were recruited for this study; 26 had premenstrual dysphoria, fulfilling criteria slightly modified from those of the premenstrual dysphoric disorder, and 26 were asymptomatic age-matched controls...
June 2012: Psychoneuroendocrinology
Alessandra Cubeddu, Fiorella Bucci, Andrea Giannini, Marinella Russo, Diana Daino, Natalia Russo, Sara Merlini, Nicola Pluchino, Valeria Valentino, Elena Casarosa, Stefano Luisi, Andrea Riccardo Genazzani
Premenstrual syndrome (PMS) is characterized by a cluster of psychological and somatic symptoms that begin during the late luteal phase of the menstrual cycle and disappear after the onset of menses. Since PMS might be caused by an alteration in the cyclical hormonal modifications and ovarian steroids are directly involved in the regulation of mood, affective and cognitive functions and influence neurotrophins expression, in particular the brain-derived neurotrophic factor (BDNF), we aimed to evaluate whether plasma BDNF levels in women with PMS differ from those of normally menstruating women without PMS...
May 2011: Psychoneuroendocrinology
P Dalén, T Vik, S Alverlind, K-G Jostell, H-G Hårdemark
In order to evaluate their potential effects on cardiac repolarization, all new drugs must undergo clinical electrocardiographic evaluation in a thorough QT/QTc (TQT) study. AZD3480, a central nervous system-selective, neuronal nicotinic receptor (NNR) agonist, is predominantly metabolized by cytochrome P450 2D6 (CYP2D6). Employing an innovative design, this TQT study assessed the effects of supratherapeutic doses of AZD3480, relative to those of placebo, on cardiac repolarization in healthy male volunteers genotyped as either poor metabolizers (PMs) or extensive metabolizers (EMs) of CYP2D6 substrates...
October 2010: Clinical Pharmacology and Therapeutics
Jumana Y Al-Aama
BACKGROUND: A compulsory national premarital screening (PMS) program for hereditary hemoglobinopathies was established in the Kingdom of Saudi Arabia (KSA) in February 2004. Termination of pregnancy of affected fetuses is not widely acceptable. Many couples decide to get married regardless of the result. A trend towards coercive interference with this decision is emerging. OBJECTIVES: To examine the attitude of young educated individuals regarding the national PMS program and its implementation...
September 2010: Health Policy
Alessandro Proclemer, Marco Ghidina, Dario Gregori, Domenico Facchin, Luca Rebellato, Edlira Zakja, Michele Gulizia, Paolo Esente
AIMS: To assess the impact on clinical practice of the major published studies, we report the information collected by the Italian Pacemaker Registry (IPR) in the quinquennium 2003-07. METHODS AND RESULTS: The IPR collected prospectively main epidemiological, clinical, and electrocardiographic data of patients treated by pacemaker (PM) in Italy on the basis of European PM Card. The number of reported PMs in Italy was 30,820 in 2003, 32,047 in 2004, 31,870 in 2005, 31,813 in 2006, and 31,146 in 2007, respectively...
February 2010: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Margaret Diana van Die, Kerry M Bone, Henry G Burger, John E Reece, Helena J Teede
BACKGROUND: It has been suggested that some of the symptoms typically attributed to menopause may be more related to premenstrual syndrome (PMS) than menopause, as perimenopausal women appear to be more prone to PMS-like symptoms, or at least to tolerate them less well. OBJECTIVE: The objective of this study was to evaluate the effectiveness of a phytotherapeutic intervention comprising a combination of Hypericum perforatum (St. John's wort) and Vitex agnus-castus (chaste tree/berry) in the management of PMS-like symptoms in perimenopausal women...
September 2009: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
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