keyword
https://read.qxmd.com/read/38535872/detection-and-phylogenetic-analysis-of-caprine-arthritis-encephalitis-virus-using-taqman-based-qpcr-in-eastern-china
#1
JOURNAL ARTICLE
Yutong Tian, Hailong Zhang, Yan Zhang, Xinya Zhang, Zhilei Guan, Junjie Zhang, Yafeng Qiu, Beibei Li, Ke Liu, Zongjie Li, Donghua Shao, Peng Li, Zhiyong Ma, Jianchao Wei
Caprine arthritis encephalitis is an infectious disease caused by the caprine arthritis encephalitis virus that infects goats, sheep, and other small ruminants. An outbreak of CAEV could be extremely harmful to the goat farming industry and could cause severe economic losses. We designed specific primers and probes for the gag gene and established a TaqMan real-time quantitative polymerase chain reaction assay. This method's correlation coefficient (R2 ) was >0.999, and the sensitivity of the assay to the plasmid-carried partial gag gene was approximately 10 copies/µL, 1000 times higher than that of conventional PCR...
March 21, 2024: Veterinary Sciences
https://read.qxmd.com/read/38535097/interventricular-septal-involvement-is-associated-with-more-impaired-ventricular-function-and-mechanics-in-apical-hypertrophic-cardiomyopathy
#2
JOURNAL ARTICLE
Christos G Mihos, Tarec K Elajami, Deepika Misra, Pranav Venkataraman, Nicholas Gosdenovich, Rafle Fernandez
BACKGROUND: The interventricular septum has an important role in bi-ventricular performance. We hypothesized that septal involvement in apical hypertrophic cardiomyopathy (ApHCM-Mixed) adversely impacts ventricular structure and function when compared with isolated apical hypertrophy (ApHCM-Pure). METHODS: A total of 72 patients (ApHCM-Mixed = 36, ApHCM-Pure = 36) with serial 2D and speckle-tracking echocardiographic analyses were identified. Ventricular function and mechanics were characterized by left (LV) and right (RV) ventricular global longitudinal strain (GLS), RV free wall strain, and LV myocardial work indices, and clinical events were adjudicated...
February 21, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38534308/vitamin-e-intake-and-prevalence-rates-of-thyroid-dysfunction-and-autoimmune-thyroiditis-a-cross-sectional-analysis-of-nhanes-data
#3
JOURNAL ARTICLE
Siying Liu, Cihang Lu, Liang He, Zhongyan Shan, Weiping Teng, Yongze Li, Liu Tingting
BACKGROUND: Thyroid disorders are associated with various dietary factors and nutritional elements. The aim of this study was to investigate the relationships between dietary vitamin E intake and the prevalence of thyroid dysfunction and thyroid antibody positivity using data from the National Health and Nutrition Examination Survey (NHANES) database. METHODS: Data from the NHANES database collected between 2007 and 2012 were analyzed. A total of 7,773 nonpregnant adults without preexisting thyroid diseases and possessing complete thyroid and vitamin E data were included in the study...
March 27, 2024: Thyroid: Official Journal of the American Thyroid Association
https://read.qxmd.com/read/38533953/polygenic-scores-and-preclinical-cardiovascular-disease-in-individuals-with-hiv-insights-from-the-reprieve-trial
#4
JOURNAL ARTICLE
Roger S Zou, Yunfeng Ruan, Buu Truong, Romit Bhattacharya, Michael T Lu, Júlia Karády, Rachel Bernardo, Phoebe Finneran, Whitney Hornsby, Kathleen V Fitch, Heather J Ribaudo, Markella V Zanni, Pamela S Douglas, Steven K Grinspoon, Aniruddh P Patel, Pradeep Natarajan
BACKGROUND: Coronary artery disease (CAD) is a leading cause of death among the 38.4 million people with HIV globally. The extent to which cardiovascular polygenic risk scores (PRSs) derived in non-HIV populations generalize to people with HIV is not well understood. METHODS AND RESULTS: PRSs for CAD (GPSMult ) and lipid traits were calculated in a global cohort of people with HIV treated with antiretroviral therapy with low-to-moderate atherosclerotic cardiovascular disease risk enrolled in REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV)...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38532734/utility-of-focused-cardiac-ultrasonography-training-in-veterinary-students-to-differentiate-stages-of-subclinical-myxomatous-mitral-valve-disease-in-dogs
#5
JOURNAL ARTICLE
Terry Huh, Erin J Achilles, Laura K Massey, Kerry A Loughran, Éva Larouche-Lebel, Victoria Convey, Victoria F McKaba, Alexandra Crooks, Marc S Kraus, Anna R Gelzer, Mark A Oyama
BACKGROUND: Differentiation of the subclinical phases of myxomatous mitral valve disease (MMVD) in dogs relies heavily on echocardiography. Focused cardiac ultrasonography (FCU) is a point-of-care technique that can assess heart size. HYPOTHESIS/OBJECTIVES: Veterinary students trained in FCU can differentiate dogs with subclinical MMVD based on left ventricular (LV) and left atrial (LA) dimensions. ANIMALS: Forty-eight dogs with subclinical MMVD...
March 27, 2024: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/38529869/-primary-prevention-of-computer-game-addiction-in-students-of-educational-institutions
#6
JOURNAL ARTICLE
R A Kardashian
OBJECTIVE: To conduct the primary prevention of computer game addiction (PPCGA) in students of General education institutions (GEI), aimed at preventing the formation of CGA. MATERIAL AND METHODS: The study included 488 students in grades 7-10 of GEI aged 12-17 years (14.6±2.4 years), of which 393 adolescents, who made up the main group, received PPCGA and 95 - control, without PPCGA. RESULTS: Preventive measures were carried out without interrupting the educational process; they were carried out by addiction psychiatrists and medical psychologists...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38529691/recurrent-hypo-attenuated-leaflet-thickening-after-tavr-clinical-implications
#7
Andrew Takla, Kirolus Sourial, Gaurav Sharma
Subclinical bioprosthetic valve thrombosis (BPVT) is a relatively common finding in asymptomatic patients during follow-up imaging. However, its clinical significance is unclear. Data from registries associate BPVT with elevated valve gradients, thromboembolic complications, recurrence, and valve degeneration. Given the dynamic nature of the disease process, management is challenging. The duration of anticoagulation is unpredictable, and the need for frequent monitoring of BPVT, even in subclinical scenarios, is unclear...
March 26, 2024: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/38528602/risk-factors-for-toxoplasma-gondii-infection-in-dogs-a-serological-survey
#8
JOURNAL ARTICLE
Filippo Maria Dini, Laura Stancampiano, Giovanni Poglayen, Roberta Galuppi
BACKGROUND: Dogs, as well as a wide variety of other warm-blooded animals, act as intermediate host of Toxoplasma gondii. In dogs, most cases of toxoplasmosis are subclinical, although clinical disease has been sporadically reported. Beyond its role in diagnostic pathways, seropositivity also functions as a reflection of the parasite's spread within the dog's living environment. The aim of the present study was to evaluate the possible risk factor associated with seropositivity to T. gondii in dogs in Central-Northern Italy, analysing 120 dogs sera for the presence of IgG antibodies by indirect fluorescence antibody test (IFAT)...
March 25, 2024: Acta Veterinaria Scandinavica
https://read.qxmd.com/read/38527485/classification-of-early-tuberculosis-states-to-guide-research-for-improved-care-and-prevention-an-international-delphi-consensus-exercise
#9
REVIEW
Anna K Coussens, Syed M A Zaidi, Brian W Allwood, Puneet K Dewan, Glenda Gray, Mikashmi Kohli, Tamara Kredo, Ben J Marais, Guy B Marks, Leo Martinez, Morten Ruhwald, Thomas J Scriba, James A Seddon, Phumeza Tisile, Digby F Warner, Robert J Wilkinson, Hanif Esmail, Rein M G J Houben
The current active-latent paradigm of tuberculosis largely neglects the documented spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic criteria for different tuberculosis states has limited the progress in research and product development that are needed to achieve tuberculosis elimination. We aimed to develop a new framework of classification for tuberculosis that accommodates key disease states but is sufficiently simple to support pragmatic research and implementation...
March 22, 2024: Lancet Respiratory Medicine
https://read.qxmd.com/read/38526356/-implications-for-clinical-decision-making-of-the-noah-afnet-6-and-artesia-studies-what-risk-benefit-ratio-of-anticoagulation-in-patients-with-subclinical-atrial-fibrillation
#10
JOURNAL ARTICLE
Giuseppe Boriani, Marta Mantovani, Chiara Birtolo, Ilaria Righelli, Luigi Gerra
No abstract text is available yet for this article.
April 2024: Giornale Italiano di Cardiologia
https://read.qxmd.com/read/38525189/the-ratio-of-systolic-and-diastolic-pressure-is-associated-with-carotid-and-femoral-atherosclerosis
#11
JOURNAL ARTICLE
Yuanping Wang, Cheng Chen, Qiaofen Lin, Qingling Su, Yiquan Dai, Hongyu Chen, Tianmin He, Xiantao Li, Ruimei Feng, Wuqing Huang, Zhijian Hu, Jun Chen, Shanshan Du, Pingfan Guo, Weimin Ye
BACKGROUND: Although the impact of hypertension on carotid intima-media thickness (IMT) and plaques has been well established, its association with femoral IMT and plaques has not been extensively examined. In addition, the role of the ratio of systolic and diastolic pressure (SDR) in the subclinical atherosclerosis (AS) risk remains unknown. We assessed the relationship between SDR and carotid and femoral AS in a general population. METHODS: A total of 7,263 participants aged 35-74 years enrolled from January 2019 to June 2021 in a southeast region of China were included in a cross-sectional study...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38524158/restless-legs-syndrome-periodic-limb-movements-of-sleep-and-subclinical-cardiovascular-disease
#12
JOURNAL ARTICLE
Kevin J Hochstrasser, Steven C Rogers, Arshed Quyyumi, Dayna Johnson, Victoria Pak, Amit J Shah, David B Rye, Lynn Marie Trotti
UNLABELLED: Restless legs syndrome (RLS) and periodic limb movements of sleep (PLMS) have been variably implicated in risk for cardiovascular disease (CVD), but there is lack of consensus on these relationships. We sought to assess subclinical CVD measures and RLS/PLMS in a large cohort to further evaluate these associations. The Emory Center for Health Discovery and Well Being cohort is composed of employed adults, with subclinical CVD measures including endothelial function (flow-mediated vasodilation), microvascular function (reactive hyperemia index, RHI), arterial stiffness (pulse wave velocity and augmentation index), and carotid intima-media thickness (cIMT)...
April 2024: Sleep and Biological Rhythms
https://read.qxmd.com/read/38523063/predictors-of-coronary-artery-calcium-burden-in-asymptomatic-patients-with-newly-diagnosed-type-2-diabetes-mellitus
#13
JOURNAL ARTICLE
Violeta Hyseni, Shpend Elezi, Bujar Gjikolli, Aurora Bakalli
OBJECTIVE: Long-standing diabetes mellitus is often associated with cardiovascular complications. We aimed to evaluate the presence, extent and composition of subclinical atherosclerotic plaques in coronary arteries by Computed Tomography in patients with newly diagnosed type 2 diabetes mellitus (NDT2DM), and to identify the predictors. METHODS: In this study 101 consecutive patients with NDT2DM were included. Patients were categorized into five groups based on their Coronary Artery Calcium Score (CACS) ranging from 0, 0-10, 11-100, 101-400 to >400...
2024: Diabetes & Vascular Disease Research
https://read.qxmd.com/read/38522898/profile-of-uterine-flush-lipid-mediators-in-cows-with-subclinical-endometritis-pilot-study
#14
JOURNAL ARTICLE
Toko Maehara, Takeshi Osawa, Go Kitahara, Hiroshi Satoh, Takahisa Murata
Subclinical endometritis affects reproductive outcomes and causes economic losses in dairy cows, thus, it is important to understand disease progression mechanisms and develop diagnostic procedures for better disease management. We measured the levels of 146 lipid mediators in uterine flush samples using lipid chromatography-mass spectrometry. We detected 25 lipid mediators in the uterine flush of both the control and subclinical endometritis cows; 15 of the 25 lipid mediators were AA-derived metabolites. Among the AA-derived metabolites, cyclooxygenase (COX)-generated mediators were the most abundant...
March 25, 2024: Journal of Veterinary Medical Science
https://read.qxmd.com/read/38522779/exploring-vaginal-discharge-scoring-to-assess-clinical-metritis-severity-comparison-between-intrauterine-dextrose-and-systemic-antibiotics-treatments
#15
JOURNAL ARTICLE
J Hamilton, E Jimenez, P Zarei, J Lection, R Sorto, E Hovingh, M Martinez, S Bas, A A Barragan
The objectives of this study were to assess: 1) differences in the metabolic status, systemic inflammation, daily milk yield, and daily rumination time between Holstein dairy cows with different vaginal discharge scores (VDS) in the first 7±3 DIM, and 2) effects of intrauterine dextrose infusion on metabolic status, systemic inflammation, daily milk yield and daily rumination time in dairy cows with VDS4 and VDS5. Cows (n=641) from a farm located in central Pennsylvania were screened at 7±3 DIM (study d 0) to assess vaginal discharge scores...
March 22, 2024: Veterinary Journal
https://read.qxmd.com/read/38522363/impact-of-adult-onset-multiple-sclerosis-on-mri-based-intracranial-volume-a-study-in-clinically-discordant-monozygotic-twins
#16
JOURNAL ARTICLE
Matin Mortazavi, Lisa Ann Gerdes, Öznur Hizarci, Tania Kümpfel, Katja Anslinger, Frank Padberg, Sophia Stöcklein, Daniel Keeser, Birgit Ertl-Wagner
OBJECTIVE: Intracranial volume (ICV) represents the maximal brain volume for an individual, attained prior to late adolescence and remaining constant throughout life after. Thus, ICV serves as a surrogate marker for brain growth integrity. To assess the potential impact of adult-onset multiple sclerosis (MS) and its preceding prodromal subclinical changes on ICV in a large cohort of monozygotic twins clinically discordant for MS. METHODS: FSL software was used to derive ICV estimates from 3D-T1-weighted-3 T-MRI images by using an atlas scaling factor method...
March 22, 2024: NeuroImage: Clinical
https://read.qxmd.com/read/38519840/quantitative-assessment-of-left-ventricular-myocardial-work-in-patients-with-different-types-of-atrial-fibrillation-by-non-invasive-pressure-strain-loop-technique
#17
JOURNAL ARTICLE
Tingting Liu, Hailan Liu, Yan Song, Yulin Huang, Chunquan Zhang
OBJECTIVE: This study aimed to analyze myocardial work in patients with atrial fibrillation (AF) using a noninvasive pressure strain loop (PSL) technique to provide a basis for the quantitative assessment of left ventricular (LV) systolic function. METHODS: LV myocardial work of 107 AF patients (56 with paroxysmal atrial fibrillation and 51 with persistent atrial fibrillation) and 55 healthy individuals were assessed by the noninvasive PSL and then compared. RESULTS: Global longitudinal strain (GLS) in absolute values, global work index (GWI), global constructive work (GCW), and global work efficiency (GWE) were significantly lower in the AF group than control group, whereas peak strain dispersion (PSD) and global wasted work (GWW) were significantly higher (P < ...
March 2024: Echocardiography
https://read.qxmd.com/read/38516169/keratoconus-exploring-fundamentals-and-future-perspectives-a-comprehensive-systematic-review
#18
REVIEW
Sana Niazi, Zisis Gatzioufas, Farideh Doroodgar, Oliver Findl, Alireza Baradaran-Rafii, Jacob Liechty, Majid Moshirfar
BACKGROUND: New developments in artificial intelligence, particularly with promising results in early detection and management of keratoconus, have favorably altered the natural history of the disease over the last few decades. Features of artificial intelligence in different machine such as anterior segment optical coherence tomography, and femtosecond laser technique have improved safety, precision, effectiveness, and predictability of treatment modalities of keratoconus (from contact lenses to keratoplasty techniques)...
2024: Therapeutic Advances in Ophthalmology
https://read.qxmd.com/read/38515536/-mycoplasma-bovis-mastitis-in-dairy-cattle
#19
REVIEW
Aga E Gelgie, Sarah E Desai, Benti D Gelalcha, Oudessa Kerro Dego
Mycoplasma bovis has recently been identified increasingly in dairy cows causing huge economic losses to the dairy industry. M. bovis is a causative agent for mastitis, pneumonia, endometritis, endocarditis, arthritis, otitis media, and many other clinical symptoms in cattle. However, some infected cows are asymptomatic or may not shed the pathogen for weeks to years. This characteristic of M. bovis , along with the lack of adequate testing and identification methods in many parts of the world until recently, has allowed the M...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38515022/association-between-short-term-blood-pressure-variability-and-target-organ-damage-in-non-dialysis-patients-with-chronic-kidney-disease
#20
JOURNAL ARTICLE
Zhaoting Chen, Xinying Jiang, Jingcan Wu, Lin Lin, Zhengping Zhou, Man Li, Cheng Wang
BACKGROUND: It is unclear whether short-term blood pressure variability (BPV) is associated with target organ damage in patients with non-dialysis chronic kidney disease (CKD). METHODS: A cross-sectional, single-center study was conducted among 3442 non-dialysis CKD patients hospitalized in the department of Nephrology of the Fifth Affiliated Hospital of Sun Yat-sen University from November 2017 to July 2022 and collected the demographic, laboratory, clinic blood pressure, ambulatory blood pressure data, and short-term BPV assessed by the weighted standard deviation (wSD) derived from ambulatory blood pressure monitoring (ABPM)...
March 21, 2024: BMC Nephrology
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