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https://www.readbyqxmd.com/read/29155335/exercise-testing-in-patients-with-diaphragm-paresis
#1
Tristan Bonnevie, Francis-Edouard Gravier, Agathe Ducrocq, David Debeaumont, Catherine Viacroze, Antoine Cuvelier, Jean-François Muir, Catherine Tardif
PURPOSE: Diaphragm paresis (DP) is characterized by abnormalities of respiratory muscle function. However, the impact of DP on exercise capacity is not well known. This study was performed to assess exercise tolerance in patients with DP and to determine whether inspiratory muscle function was related to exercise capacity, ventilatory pattern and cardiovascular function during exercise. METHODS: This retrospective study included patients with DP who underwent both diaphragmatic force measurements, and cardiopulmonary exercise testing (CPET)...
November 16, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29154420/relationship-between-skeletal-muscle-mass-and-cardiac-function-during-exercise-in-community-dwelling-older-adults
#2
Masamitsu Sugie, Kazumasa Harada, Tetsuya Takahashi, Marina Nara, Joji Ishikawa, Teruyuki Koyama, Hunkyung Kim, Jun Tanaka, Hajime Fujimoto, Shuichi Obuchi, Stephan von Haehling, Syunei Kyo, Hideki Ito
AIMS: This study aimed to investigate the relationship between skeletal muscle mass and cardiac functional parameters in older adults during cardiopulmonary exercise testing (CPET). METHODS AND RESULTS: Sixty-three Japanese community-dwelling older adults were enrolled (20 men and 43 women; mean age 80 years, range 65-97 years). Cardiac functional parameters during exercise were assessed using CPET. Skeletal muscle mass index (SMI) was calculated by dividing the appendicular lean mass (measured using dual-energy X-ray absorptiometry) by height in metres squared...
November 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29143123/recovery-of-the-cardiac-autonomic-nervous-and-vascular-system-after-maximal-cardiopulmonary-exercise-testing-in-recreational-athletes
#3
Heidi Weberruss, Johannes Maucher, Renate Oberhoffer, Jan Müller
OBJECTIVE: The body's adaptation to physical exercise is modulated by sympathetic and parasympathetic (vagal) branches of the autonomic nervous system (ANS). Heart rate variability (HRV), the beat-to-beat variation of the heart, is a proxy measure for ANS activity, whereas blood pressure (BP) is an indicator for cardiovascular function. Impaired vagal activity and lower BP is already described after exercise. However, inconsistent results exist about how long vagal recovery takes and how long post-exercise hypotension persists...
November 15, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29143104/left-ventricular-end-diastolic-dimension-and-septal-e-are-predictors-of-cardiac-index-at-rest-while-tricuspid-annular-plane-systolic-excursion-is-a-predictor-of-peak-oxygen-uptake-in-patients-with-pulmonary-hypertension
#4
Yoshihisa Nakano, Naoki Okumura, Shiro Adachi, Shigetake Shimokata, Fumitaka Tajima, Yoshihiro Kamimura, Toyoaki Murohara, Takahisa Kondo
Little is known regarding a correlation of hemodynamics at rest or exercise capacity with echocardiographic parameters in patients with pulmonary hypertension (PH). To clarify these potential correlations, we performed transthoracic echocardiography, right heart catheterization, and cardiopulmonary exercise testing in 53 patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). Left ventricular end-diastolic dimension (LVDd), early diastolic velocity of the septal mitral annulus (septal e'), tricuspid regurgitation peak gradient (TRPG), and tricuspid annular plane systolic excursion (TAPSE) were significantly correlated with cardiac index (LVDd; r = 0...
November 15, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29140739/cftr-genotype-and-maximal-exercise-capacity-in-cystic-fibrosis-a-cross-sectional-study
#5
Thomas Radtke, Helge Hebestreit, Sabina Gallati, Jane E Schneiderman, Julia Braun, Daniel Stevens, Erik Hj Hulzebos, Tim Takken, Steven R Boas, Don S Urquhart, Larry C Lands, Sergio Tejero, Aleksandar Sovtic, Tiffany Dwyer, Milos Petrovic, Ryan A Harris, Chantal Karila, Daniela Savi, Jakob Usemann, Meir Mei-Zahav, Elpis Hatziagorou, Felix Ratjen, Susi Kriemler
RATIONALE: Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in human skeletal muscle cells. Variations of CFTR dysfunction among patients with CF may present an important determinant of aerobic exercise capacity in CF. Previous studies on the relationship between CFTR genotype and aerobic exercise capacity are scarce and contradictory. OBJECTIVES: This study was designed to explore factors influencing aerobic exercise capacity, expressed as peak oxygen consumption (VO2peak) with a specific focus on CFTR genotype in children and adults with CF...
November 15, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29128863/persistent-long-term-structural-functional-and-metabolic-changes-after-stress-induced-takotsubo-cardiomyopathy
#6
Caroline Scally, Amelia Rudd, Alice Mezincescu, Heather Wilson, Janaki Srinivasan, Graham Horgan, Paul Broadhurst, David E Newby, Anke Henning, Dana K Dawson
BACKGROUND : Takotsubo cardiomyopathy is an increasingly recognized acute heart failure syndrome precipitated by intense emotional stress. Although there is an apparent rapid and spontaneous recovery of left ventricular ejection fraction, the long-term clinical and functional consequences of takotsubo cardiomyopathy are ill-defined. METHODS : In an observational case-control study, we recruited 37 patients with prior (>12-month) takotsubo cardiomyopathy, and 37 age-, sex-, and comorbidity-matched control subjects...
November 11, 2017: Circulation
https://www.readbyqxmd.com/read/29126582/effect-of-body-mass-index-on-exercise-capacity-in-patients-with-hypertrophic-cardiomyopathy
#7
Carolyn M Larsen, Caroline A Ball, Virginia B Hebl, Kevin C Ong, Konstantinos C Siontis, Thomas P Olson, Michael J Ackerman, Steve R Ommen, Thomas G Allison, Jeffrey B Geske
The objective of this study was to evaluate the relation between body mass index (BMI), exercise capacity, and symptoms in patients with hypertrophic cardiomyopathy (HC) and to utilize results of cardiopulmonary exercise tests (CPX) and transthoracic echocardiograms to understand the mechanism(s) of reduced exercise capacity across body mass index groups. Over a 6-year period, 510 consecutive patients with HC seen at a tertiary referral center underwent (CPX) and a transthoracic echocardiogram. Increasing BMI was associated with decreased exercise capacity as assessed by peak VO2 (ml/kg/min)...
October 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29122139/role-of-exercise-testing-in-hypertrophic%C3%A2-cardiomyopathy
#8
REVIEW
Ethan J Rowin, Barry J Maron, Iacopo Olivotto, Martin S Maron
Over the last 25 years, patients with hypertrophic cardiomyopathy (HCM) have been studied with a variety of methods employing physiological exercise that have made major contributions to disease management and are performed without increased risk. Previously under-utilized in HCM, exercise (stress) echocardiography has become incorporated into the standard clinical assessment and diagnostic armamentarium of HCM using upright or supine symptom-limited treadmill or bicycle modalities. In patients without outflow gradients at rest, exercise echocardiography is the most appropriate method for provoking obstruction, with the capability of predicting future development of progressive heart failure symptoms, and differentiating patients with provocable obstruction from those without obstruction, with major implications for dictating treatment options, that is, surgical myectomy (alternatively, alcohol septal ablation) versus heart transplant...
November 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29121320/cardiopulmonary-exercise-testing-in-preoperative-risk-assessment-and-patient-management
#9
P Older, A Hall
No abstract text is available yet for this article.
October 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29119294/predictors-of-improvements-in-exercise-capacity-during-cardiac-rehabilitation-in-the-recovery-phase-after-coronary-artery-bypass-graft-surgery-versus-acute-myocardial-infarction
#10
Yuji Suzuki, Kenichi Ito, Kazuya Yamamoto, Noriyuki Fukui, Hidetoshi Yanagi, Kazufumi Kitagaki, Harumi Konishi, Tetsuo Arakawa, Michio Nakanishi, Yoichi Goto
This study aimed to elucidate the predictors of improvements in exercise capacity during cardiac rehabilitation (CR) in the recovery phase after coronary artery bypass graft surgery (CABG) versus acute myocardial infarction (AMI). We studied 152 patients (91 after AMI and 61 after CABG) who participated in a 3-month CR program. All patients underwent a cardiopulmonary exercise test, blood tests, maximal quadriceps isometric strength (QIS) measurement, and bioelectrical impedance body composition measurement at the beginning and end of the 3-month CR program...
November 8, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29115721/loss-of-skeletal-muscle-mass-in-patients-with-chronic-liver-disease-is-related-to-decrease-in-bone-mineral-density-and-exercise-tolerance
#11
Fumikazu Hayashi, Masaki Kaibori, Tatsuma Sakaguchi, Kosuke Matsui, Morihiko Ishizaki, A-Hon Kwon, Junji Iwasaka, Yutaka Kimura, Daiki Habu
AIM: This study aimed to identify the relationship between loss of skeletal muscle mass and clinical factors such as osteoporosis in patients with chronic liver disease. METHODS: The subjects were 112 patients (85 men, 27 women) with hepatocellular carcinoma who were scheduled to undergo hepatectomy. Skeletal muscle reduction was diagnosed according to the cutoff level of the skeletal mass index (SMI) for Asians (men <7.0 kg/m(2) , women <5.4 kg/m(2) ). Osteoporosis was diagnosed according to T-score ≤-2...
November 8, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/29115018/relationship-between-exercise-capacity-and-glucose-tolerance-in-cystic-fibrosis
#12
Karla Foster, Guixia Huang, Nanhua Zhang, Joseph Crisalli, Barbara Chini, Raouf Amin, Deborah Elder
BACKGROUND: Improved exercise capacity (EC) and normal glucose tolerance (NGT) are independently associated with favorable outcomes in CF, however, little information on this relationship exists in patients with CF. METHODS: Cardiopulmonary exercise tests, oral glucose tolerance tests (OGTT), and HbA1c values measured within a 12-month period were evaluated on 83 pediatric patients diagnosed with CF. Patients were categorized as having NGT, abnormal glucose tolerance (AGT), or CF-related diabetes (CFRD)...
November 8, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29105515/implementation-and-evaluation-of-the-norwegian-ullevaal-model-as-a-cardiac-rehabilitation-model-in-primary-care
#13
Birgitta Blakstad Nilsson, Pernille Lunde, Inger Holm
PURPOSE: To describe the Norwegian Ullevaal model, customised for cardiac patients in primary care, and to evaluate the feasibility of the model through patient outcomes after the 12 week outpatient cardiac rehabilitation programme. MATERIALS AND METHODS: A descriptive interventional cohort study with pre-post design. Patients referred to cardiac rehabilitation (n = 273) were enrolled. Group-based high-intensity interval training was offered twice weekly. The primary outcome measure was change in peak oxygen uptake...
November 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29103656/percutaneous-coronary-intervention-in-stable-angina-orbita-a-double-blind-randomised-controlled-trial
#14
Rasha Al-Lamee, David Thompson, Hakim-Moulay Dehbi, Sayan Sen, Kare Tang, John Davies, Thomas Keeble, Michael Mielewczik, Raffi Kaprielian, Iqbal S Malik, Sukhjinder S Nijjer, Ricardo Petraco, Christopher Cook, Yousif Ahmad, James Howard, Christopher Baker, Andrew Sharp, Robert Gerber, Suneel Talwar, Ravi Assomull, Jamil Mayet, Roland Wensel, David Collier, Matthew Shun-Shin, Simon A Thom, Justin E Davies, Darrel P Francis
BACKGROUND: Symptomatic relief is the primary goal of percutaneous coronary intervention (PCI) in stable angina and is commonly observed clinically. However, there is no evidence from blinded, placebo-controlled randomised trials to show its efficacy. METHODS: ORBITA is a blinded, multicentre randomised trial of PCI versus a placebo procedure for angina relief that was done at five study sites in the UK. We enrolled patients with severe (≥70%) single-vessel stenoses...
November 1, 2017: Lancet
https://www.readbyqxmd.com/read/29096886/long-term-results-of-high-intensity-exercise-based-cardiac-rehabilitation-in-revascularized-patients-for-symptomatic-coronary-artery-disease
#15
Birgitta Blakstad Nilsson, Pernille Lunde, Haakon Kiil Grøgaard, Inger Holm
Exercise capacity is a strong predictor of survival rate in patients with and without coronary artery disease. Exercise-based cardiac rehabilitation (CR) with improvements in the peak oxygen uptake (VO2peak) of 3.5 ml/kg/min or more has been shown to be beneficial in earlier observational studies. Long-term results on VO2peak after CR are rare. The aim of this study was to assess if a 12-week outpatient CR program including high-intensity interval training would preserve or improve VO2peak 15 months after CR entry...
October 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29093153/limited-exercise-capacity-in-patients-with-systemic-sclerosis-identifying-contributing-factors-with-cardiopulmonary-exercise-testing
#16
Nihal Martis, Viviane Queyrel-Moranne, David Launay, Rémi Neviere, Jean-Gabriel Fuzibet, Charles-Hugo Marquette, Sylvie Leroy
OBJECTIVE: Exercise limitation in patients with systemic sclerosis (SSc) is often multifactorial and related to complications such as interstitial lung disease (ILD), pulmonary vasculopathy (PV), left ventricular dysfunction (LVD), and/or peripheral/muscular limitation (PML). We hypothesized that cardiopulmonary exercise testing (CPET) could not only suggest and rank competing etiologies, but also highlight peripheral impairment. METHODS: Clinical, resting pulmonary function testing, and CPET data from patients with SSc referred for exercise limitation between October 2009 and November 2015 were retrospectively analyzed in this bi-center study...
November 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29089343/impact-of-atrial-fibrillation-on-exercise-capacity-and-mortality-in-heart-failure-with-preserved-ejection-fraction-insights-from-cardiopulmonary-stress-testing
#17
Mohamed B Elshazly, Todd Senn, Yuping Wu, Bruce Lindsay, Walid Saliba, Oussama Wazni, Leslie Cho
BACKGROUND: Atrial fibrillation (AF) has been objectively associated with exercise intolerance in patients with heart failure with reduced ejection fraction; however, its impact in patients with heart failure with preserved ejection fraction has not been fully scrutinized. METHODS AND RESULTS: We identified 1744 patients with heart failure and ejection fraction ≥50% referred for cardiopulmonary stress testing at the Cleveland Clinic (Cleveland, OH), 239 of whom had AF...
October 31, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29089342/prognostic-value-of-cardiopulmonary-exercise-testing-in-heart-failure-with-reduced-midrange-and-preserved-ejection-fraction
#18
Wilson Nadruz, Erin West, Morten Sengeløv, Mário Santos, John D Groarke, Daniel E Forman, Brian Claggett, Hicham Skali, Amil M Shah
BACKGROUND: This study aimed to compare the independent and incremental prognostic value of peak oxygen consumption (VO2) and minute ventilation/carbon dioxide production (VE/VCO2) in heart failure (HF) with preserved (HFpEF), midrange (HFmEF), and reduced (HFrEF) ejection fraction (LVEF). METHODS AND RESULTS: In 195 HFpEF (LVEF ≥50%), 144 HFmEF (LVEF 40-49%), and 630 HFrEF (LVEF <40%) patients, we assessed the association of cardiopulmonary exercise testing variables with the composite outcome of death, left ventricular assist device implantation, or heart transplantation (256 events; median follow-up of 4...
October 31, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29082512/cardiopulmonary-exercise-test-predicts-right-heart-catheterization
#19
Michele Correale, Lucia Tricarico, Armando Ferraretti, Ilenia Monaco, Morena Concilio, Giuseppina Padovano, Gianfranco Acanfora, Matteo Di Biase, Natale Daniele Brunetti
BACKGROUND: Right heart catheterization (RHC) is usually required to confirm the diagnosis of pulmonary artery hypertension (PAH). As an invasive test, RHC may be associated with possible complications; so, non-invasive parameters able to predict PAH at RHC would be extremely useful. AIM: To ascertain possible correlations between cardiopulmonary exercise testing (CPET) and hemodynamic parameters at RHC indicative of PH. METHODS: Thirty-six consecutive outpatients with suspect of PAH underwent CPET and RHC; the intercept of ventilation (VEint) on the VE vs...
October 30, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29071437/effect-of-long-term-remote-ischemic-conditioning-in-patients-with-chronic-ischemic-heart-failure
#20
Kasper Pryds, Roni Ranghøj Nielsen, Anders Jorsal, Mona Sahlholdt Hansen, Steffen Ringgaard, Jens Refsgaard, Won Yong Kim, Annemette Krintel Petersen, Hans Erik Bøtker, Michael Rahbek Schmidt
Remote ischemic conditioning (RIC) protects against acute ischemia-reperfusion injury and may also have beneficial effects in patients with stable cardiovascular disease. We investigated the effect of long-term RIC treatment in patients with chronic ischaemic heart failure (CIHF). In a parallel group study, 22 patients with compensated CIHF and 21 matched control subjects without heart failure or ischemic heart disease were evaluated by cardiac magnetic resonance imaging, cardiopulmonary exercise testing, skeletal muscle function testing, blood pressure measurement and blood sampling before and after 28 ± 4 days of once daily RIC treatment...
October 25, 2017: Basic Research in Cardiology
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