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Oncology parenteral nutrition

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https://www.readbyqxmd.com/read/28558699/incidence-of-and-factors-associated-with-catheter-related-bloodstream-infection-in-patients-with-advanced-solid-tumors-on-home-parenteral-nutrition-managed-using-a-standardized-catheter-care-protocol
#1
Pankaj G Vashi, Natasha Virginkar, Brenten Popiel, Persis Edwin, Digant Gupta
BACKGROUND: Catheter-related bloodstream infections (CRBSIs) are associated with high morbidity and mortality as well as increased medical costs. Cancer patients, who are often immunocompromised, are susceptible to CRBSI while receiving home parenteral nutrition (HPN). We evaluated the incidence of and factors associated with CRBSIs in cancer patients undergoing HPN managed using a standardized catheter care protocol. METHODS: This is a retrospective cohort study of 335 cancer patients receiving HPN between January 2012 and July 2015...
May 30, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28557362/longitudinal-study-of-quality-of-life-in-advanced-cancer-patients-on-home-parenteral-nutrition
#2
Paolo Cotogni, Luca De Carli, Roberto Passera, Maria Luisa Amerio, Elena Agnello, Maurizio Fadda, Marta Ossola, Taira Monge, Antonella De Francesco, Federico Bozzetti
Since there is little knowledge regarding the quality of life (QoL) of cancer patients on home parenteral nutrition (HPN), we planned a prospective, longitudinal, double-center study to investigate the changes of QoL in these patients. One hundred and eleven adult cancer patients who were candidates for HPN following the indications of the European guidelines were consecutively enrolled. For QoL analysis, EORTC QLQ-C30 questionnaires were filled at the HPN start and after 1, 2, 3, and 4 months, and scores changes over time were analyzed according to the univariate mixed-effects linear model for repeated measures...
May 29, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28481857/the-evolution-of-pelvic-exenteration-practice-at-a-single-center-lessons-learned-from-over-500-cases
#3
Cherry E Koh, Michael J Solomon, Kilian G Brown, Kirk Austin, Christopher M Byrne, Peter Lee, Jane M Young
Considerable progress has been made in the management of patients with locally advanced or recurrent cancers of the pelvis over the past 60 years since the inception of pelvic exenteration. Early progress in pelvic exenteration was marred by the high surgical mortality and morbidity, which drew scepticism from the broader surgical community. Subsequent evolution in the procedure hinged on establishing surgical safety and a better understanding of outcome predictors. Surgical mortality from pelvic exenteration is now comparable to that of elective resection for primary colorectal cancers...
June 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28462518/alvimopan-for-recovery-of-bowel-function-after-radical-cystectomy
#4
REVIEW
Shahnaz Sultan, Bernadette Coles, Philipp Dahm
BACKGROUND: Alvimopan is used in abdominal surgery to reduce postoperative ileus in patients undergoing small bowel resections with primary anastomosis. The role and efficacy of alvimopan in patients undergoing radical cystectomy with urinary diversion is not well understood. OBJECTIVES: To assess the effects of alvimopan in the context of enhanced recovery pathways compared to enhanced recovery pathways alone for perioperative bowel dysfunction in patients undergoing radical cystectomy...
May 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27770454/oncological-and-functional-outcomes-of-postoperative-total-parenteral-nutrition-after-radical-cystectomy-in-bladder-cancer-patients-a-single-center-randomized-trial
#5
Alvaro Vidal, Nicolas Arnold, Mihai Dorin Vartolomei, Bernhard Kiss, Fiona Burkhard, George N Thalmann, Beat Roth
OBJECTIVES: To prospectively evaluate the long-term oncological and functional outcomes of postoperative total parenteral nutrition after radical cystectomy. METHODS: A total of 157 consecutive patients (≤cT3, cN0, cM0) who underwent extended pelvic lymph node dissection, radical cystectomy and ileal urinary diversion from September 2008 to March 2011 at a single center were randomized to receive either postoperative total parenteral nutrition (group A; n = 74) or oral nutrition alone (group B; n = 83)...
December 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/27621004/impact-of-malnutrition-on-gastrointestinal-surgical-patients
#6
Catalina Mosquera, Nicholas J Koutlas, Kimberly C Edwards, Ashley Strickland, Nasreen A Vohra, Emmanuel E Zervos, Timothy L Fitzgerald
BACKGROUND: The accurate diagnosis of malnutrition is imperative if we are to impact outcomes in the malnourished. The American Society of Parenteral and Enteral Nutrition (ASPEN) and Academy of Nutrition and Dietetics (AND), in an attempt to address this issue, have provided evidence-based criteria to diagnose malnutrition. The purpose of this study was to validate the ASPEN/AND criteria in a cohort of patients from a single high-volume surgical oncology unit. METHODS: Patients undergoing major abdominal surgery from June 2013 to March 2015 were classified by their nutritional status using the ASPEN/AND criteria...
September 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27230757/breast-cancer-integrative-oncology-care-and-its-costs
#7
Leanna J Standish, Fred Dowd, Erin Sweet, Linda Dale, Morgan Weaver, Barbara Osborne, M Robyn Andersen
BACKGROUND: Naturopathic oncology in conjunction with conventional treatment is commonly referred to as integrative oncology (IO). Clinics directed by oncology board certified NDs (Fellows of the American Board of Naturopathic Oncology or FABNOs) provide high-quality data for describing IO therapies, their costs and measuring clinical outcomes. PURPOSE: To describe the types of IO therapies prescribed to breast cancer patients by ND FABNO physicians. Study participants (n = 324)...
May 26, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27107610/low-bacterial-diet-versus-control-diet-to-prevent-infection-in-cancer-patients-treated-with-chemotherapy-causing-episodes-of-neutropenia
#8
REVIEW
Elvira C van Dalen, Arno Mank, Edith Leclercq, Renée L Mulder, Michelle Davies, Marie José Kersten, Marianne D van de Wetering
BACKGROUND: Neutropenia is a potentially serious side effect of chemotherapy and a major risk factor for infection, which can be life-threatening. It has been hypothesised that a low bacterial diet (LBD) can prevent infection and (infection-related) mortality in cancer patients receiving chemotherapy that causes episodes of neutropenia, but much remains unclear. This review is an update of a previously published Cochrane review. OBJECTIVES: The primary objective of this review was to determine the efficacy of an LBD versus a control diet in preventing infection and in decreasing (infection-related) mortality in adult and paediatric cancer patients receiving chemotherapy that causes episodes of neutropenia...
April 24, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27068496/central-venous-catheter-related-bloodstream-infections-in-adult-patients-on-home-parenteral-nutrition-prevalence-predictive-factors-therapeutic-outcome
#9
Lidia Santarpia, Antonio Buonomo, Maria Carmen Pagano, Lucia Alfonsi, Maria Foggia, Michele Mottola, Geremia Zito Marinosci, Franco Contaldo, Fabrizio Pasanisi
BACKGROUND: The prevalence of central venous catheter (CVC)-related blood-stream infections (CRBSI), infecting agents and the effectiveness of antibiotic therapy were evaluated in 172 adult patients on Home Parenteral Nutrition (HPN) at the Clinical Nutrition Outpatient Unit of Federico II University Hospital in Naples, Italy. MATERIALS AND METHODS: The study population consisted of 127 oncological (74%) and 45 (26%) non-oncological patients, for a total of 53,818 (median 104; range 14-1080) CVC days...
December 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/26982376/catheter-impregnation-coating-or-bonding-for-reducing-central-venous-catheter-related-infections-in-adults
#10
REVIEW
Nai Ming Lai, Nathorn Chaiyakunapruk, Nai An Lai, Elizabeth O'Riordan, Wilson Shu Cheng Pau, Sanjay Saint
BACKGROUND: The central venous catheter (CVC) is essential in managing acutely ill patients in hospitals. Bloodstream infection is a major complication in patients with a CVC. Several infection control measures have been developed to reduce bloodstream infections, one of which is impregnation of CVCs with various forms of antimicrobials (either with an antiseptic or with antibiotics). This review was originally published in June 2013 and updated in 2016. OBJECTIVES: Our main objective was to assess the effectiveness of antimicrobial impregnation, coating or bonding on CVCs in reducing clinically-diagnosed sepsis, catheter-related blood stream infection (CRBSI), all-cause mortality, catheter colonization and other catheter-related infections in adult participants who required central venous catheterization, along with their safety and cost effectiveness where data were available...
March 16, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26886037/-weight-loss-in-cancer-patients
#11
Florian Lordick, Ulrich Hacker
Cancer patients are regularly affected by malnutrition which often leads to a worsened quality of life and activity in daily living, more side effects and complications during anticancer treatment and shorter survival times. The early diagnosis and treatment of malnutrition are therefore relevant components of oncological treatment. The assessment of the nutritional status and determination of the body-mass-index should be done in every patient with cancer. The clinical examination delivers important findings and indications for malnutrition...
February 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/26869656/recap-detection-of-potentially-avoidable-harm-in-oncology-from-patient-medical-records
#12
Allison Lipitz-Snyderman, Saul N Weingart, Christopher Anderson, Andrew S Epstein, Aileen Killen, David Classen, Camelia S Sima, Elizabeth Fortier, Coral L Atoria, David Pfister, Allison Lipitz-Snyderman, Saul N Weingart, Christopher Anderson, Andrew S Epstein, Aileen Killen, David Classen, Camelia S Sima, Elizabeth Fortier, Coral L Atoria, David Pfister
PURPOSE: Widespread consensus exists about the importance of addressing patient safety issues in oncology, yet our understanding of the frequency, spectrum, and preventability of adverse events (AEs) across cancer care is limited. METHODS: We developed a screening tool to detect AEs across cancer care settings through medical record review. Members of the study team reviewed the scientific literature and obtained structured input from an external multidisciplinary panel of clinicians by using a modified Delphi process...
February 2016: Journal of Oncology Practice
https://www.readbyqxmd.com/read/26853395/parenteral-and-enteral-nutrition-for-pediatric-oncology-in-low-and-middle-income-countries
#13
REVIEW
K Viani
Although nutritional therapy is essential for the treatment of childhood cancer, it remains a challenge, especially within the developing world, where there are many barriers to optimizing treatment. The oral route is the first approach to nutritional support, however challenging this might be in children with cancer. Oral supplements are indicated in moderate evaluated nutritional risk patients and its use should consider the family's social conditions and access to industrialized oral supplements. If unavailable, homemade oral supplements can be used respecting regional accessibility, local foods, and culture...
April 2015: Indian Journal of Cancer
https://www.readbyqxmd.com/read/26841814/enteral-versus-parenteral-nutrition-in-cancer-patients-evidences-and-controversies
#14
REVIEW
Paolo Cotogni
The debate over the use of enteral nutrition (EN) and parenteral nutrition (PN) is an old but evergreen and hot topic. Since many years, studies comparing EN and PN have been a pivotal 'leitmotif' in the published literature on artificial nutrition (AN). Actually, there is a background misunderstanding in this debate; specifically, that EN and PN are competitors in the choice of the route for delivering nutrition support in cancer patients. Conversely, EN and PN have specific indications and contraindications...
January 2016: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/26837159/-vitamin-d-in-oncology-update-2015
#15
Uwe Gröber, Klaus Kisters, Irenäus A Adamietz
Vitamin D deficiency is associated with increased incidence of breast and colon cancer as well as with an unfavourable course of non-Hodgkin lymphoma. Vitamin D deficiency is common in cancer patients and is associated with poor cancer prognosis and disease progression. In breast cancer patients under polychemotherapy with anthracycline and taxane, a significant drop in 25(OH)D levels was observed. Osteo-malacia represents a new and previously unreported risk factor for the development of bisphosphonate-related osteonecrosis of the jaw...
December 2015: Medizinische Monatsschrift Für Pharmazeuten
https://www.readbyqxmd.com/read/26832816/utilization-of-a-nutrition-support-algorithm-reduces-unnecessary-parenteral-nutrition-use-in-pediatric-oncology-inpatients
#16
Caroline Steele, Angela Salazar, Lindsay Rypkema
No abstract text is available yet for this article.
August 2016: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/26743773/catheter-related-complications-in-children-with-cancer-receiving-parenteral-nutrition-change-in-risk-is-moderated-by-catheter-type
#17
Melissa A Shenep, Mary R Tanner, Yilun Sun, Tina Culley, Randall T Hayden, Patricia M Flynn, Li Tang, Joshua Wolf
BACKGROUND: Although central venous catheters (CVCs) are essential to pediatric cancer care, complications are common (eg, occlusion, central line-associated bloodstream infection [CLABSI]). Parenteral nutrition (PN) and external CVCs are associated with an increased complication risk, but their interaction is unknown. METHODS: A retrospective matched cohort study of pediatric oncology patients who received PN through subcutaneous ports or external CVCs. Complication rates were compared between CVC types during PN and non-PN periods (log-negative binomial model)...
January 7, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/26721695/health-care-providers-perceptions-of-nutrition-support-in-pediatric-oncology-and-hematopoietic-stem-cell-transplant-patients
#18
Kathleen Montgomery, Meghan Belongia, Christina Schulta, Mollie Haddigan Mulberry, Melodee L Nugent, Pippa M Simpson
One of the most common side effects of medical treatment for patients with an oncologic diagnosis is malnutrition. There is limited research that broadly assesses the perceptions of health care providers (HCPs) regarding nutrition support in the pediatric population. The purpose of this study was to describe the perceptions of nutrition support among pediatric oncology and hematopoietic stem cell transplant HCPs. The study used a cross-sectional descriptive design using a 31-item survey. Results of the survey indicated that nurses were more likely to initiate conversations about nutrition support during the first month of diagnosis, while midlevel providers and physicians initiated discussions in response to a change in nutritional status evidenced by decreased oral intake or weight loss...
July 2016: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/26546372/factors-influencing-antimicrobial-resistance-and-outcome-of-gram-negative-bloodstream-infections-in-children
#19
MULTICENTER STUDY
Balázs Ivády, Éva Kenesei, Péter Tóth-Heyn, Gabriella Kertész, Klára Tárkányi, Csaba Kassa, Enikő Ujhelyi, Borbála Mikos, Erzsébet Sápi, Krisztina Varga-Heier, Gábor Guóth, Dóra Szabó
OBJECTIVE: The aim of this study was to collect data about pediatric Gram-negative bloodstream infections (BSI) to determine the factors that influence multidrug resistance (MDR), clinical course and outcome of children affected by Gram-negative sepsis. METHODS: In this observational, prospective, multicenter study we collected cases of pediatric Gram-negative BSI during a 2-year period. We analyzed epidemiological, microbiological and clinical factors that associated with acquisition of MDR infections and outcome...
June 2016: Infection
https://www.readbyqxmd.com/read/26391328/impact-of-processes-of-care-aimed-at-complication-reduction-on-the-cost-of-complex-cancer-surgery
#20
Marah N Short, Vivian Ho, Thomas A Aloia
BACKGROUND AND OBJECTIVES: Health care providers add multiple processes to the care of complex cancer patients, believing they prevent and/or ameliorate complications. However, the relationship between these processes, complication remediation, and expenditures is unknown. METHODS: Data for patients with cancer diagnoses undergoing colectomy, rectal resection, pulmonary lobectomy, pneumonectomy, esophagectomy, and pancreatic resection were obtained from hospital and inpatient physician Medicare claims for the years 2005-2009...
November 2015: Journal of Surgical Oncology
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