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https://www.readbyqxmd.com/read/29341456/iron-pill-aspiration-cytologic-and-histologic-findings-of-a-potential-life-threatening-airway-injury-a-case-report-and-literature-review
#1
Vanessa Henriques, Diogo Costa Santos, Graça Lérias, Lucília Cáceres Monteiro
Iron pill-induced injury of bronchial mucosa is a complication following accidental aspiration of an iron tablet. Oral iron supplementation is a common therapy, particularly among advanced-age patients, who are more prone to aspiration. However, iron pill aspiration has been rarely reported in the literature, usually under the format of short case reports, with only 32 cases published in the literature. The cytologic features suspicious for this rare but potentially lethal entity have been seldom described...
January 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29302540/a-chart-review-of-morbidity-patterns-among-adult-patients-attending-primary-care-setting-in-urban-odisha-india-an-international-classification-of-primary-care-experience
#2
Subhashisa Swain, Sandipana Pati, Sanghamitra Pati
Introduction: Disease burden estimations based on sound epidemiological research provide the foundation for designing health services. Patients visiting a primary care often present with symptoms and signs. Understanding the burden is crucial for developing countries including India. The project aimed to record the reasons for encounter (RFE) at primary care settings for estimating the burden at the health-care facility. Methodology: This cross-sectional study was undertaken at four urban health dispensaries of Bhubaneswar, Odisha, with the aim to explore the prevailing patterns of diseases among patients attending these facilities...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29298963/-bronchipret-te%C3%A2-in-therapy-of-acute-infections-of-the-respiratory-tract
#3
Agnieszka Mastalerz-Migas, Zbigniew Doniec, Tadeusz Płusa
Bronchipret TE® exhibits multidirectional anti-inflammatory effects as demonstrated in vitro and in vivo studies. It has been disclosed that the drug has the ability to activate the bronchial cleaning mechanism, inhibit the respiratory tract remodeling process by reducing the number of goblet cells, inhibiting enzyme activity and proinflammatory mediators. These mechanisms cause the administration of medication to cause acute bronchitis patients to shorten and alleviate the course of the disease with rapid cough elimination...
December 22, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29277082/routes-of-administration-for-cannabis-use-basic-prevalence-and-related-health-outcomes-a-scoping-review-and-synthesis
#4
Cayley Russell, Sergio Rueda, Robin Room, Mark Tyndall, Benedikt Fischer
BACKGROUND: Cannabis use is common, and associated with adverse health outcomes. 'Routes of administration' (ROAs) for cannabis use have increasingly diversified, in part influenced by developments towards legalization. This paper sought to review data on prevalence and health outcomes associated with different ROAs. METHODS: This scoping review followed a structured approach. Electronic searches for English-language peer-reviewed publications were conducted in primary databases (i...
December 22, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29240687/decreasing-inappropriate-use-of-antibiotics-in-primary-care-in-four-countries-in-south-america-cluster-randomized-controlled-trial
#5
Inés Urbiztondo, Lars Bjerrum, Lidia Caballero, Miguel Angel Suarez, Monica Olinisky, Gloria Córdoba
High antibiotic prescribing and antimicrobial resistance in patients attending primary care have been reported in South America. Very few interventions targeting general practitioners (GPs) to decrease inappropriate antibiotic prescribing have been investigated in this region. This study assessed the effectiveness of online feedback on reducing antibiotic prescribing in patients with suspected respiratory tract infections (RTIs) attending primary care. The aim was to reduce antibiotic prescribing in patients with acute bronchitis and acute otitis media...
December 14, 2017: Antibiotics
https://www.readbyqxmd.com/read/29238574/role-of-guaifenesin-in-the-management-of-chronic-bronchitis-and-upper-respiratory-tract-infections
#6
REVIEW
Helmut H Albrecht, Peter V Dicpinigaitis, Eric P Guenin
Guaifenesin, a mucoactive drug, acts by loosening mucus in the airways and making coughs more productive. It is used for relief of wet cough and chest congestion due to the common cold, and remains the only legally marketed expectorant in the US (per OTC Monograph). An ingredient in numerous over-the-counter (OTC) cough/cold medications, guaifenesin has a secondary indication for use in stable chronic bronchitis (professional indication). Clinical pharmacology and patient studies support the clinical utility of guaifenesin in respiratory conditions where mucus hypersecretion is prevalent: acute upper respiratory tract infections (URTIs), stable chronic bronchitis, and possibly rhinosinusitis...
2017: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29229092/predictors-of-smoking-cessation-a-longitudinal-study-in-a-large-cohort-of-smokers
#7
Mathias Holm, Linus Schiöler, Eva Andersson, Bertil Forsberg, Thorarinn Gislason, Christer Janson, Rain Jogi, Vivi Schlünssen, Cecilie Svanes, Kjell Torén
BACKGROUND: There are few studies on predictors of smoking cessation in general populations. We studied the smoking cessation rate in relation to several potential predictors, with special focus on respiratory and cardiovascular disease. METHODS: Smokers (n = 4636) from seven centres in Northern Europe, born between 1945 and 1973, who answered a questionnaire in 1999-2001 (the RHINE study) were followed up with a new questionnaire in 2010-2012. Altogether 2564 answered the questionnaire and provided complete data on smoking...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29209859/spicae-aetheroleum-in-uncomplicated-acute-bronchitis-a%C3%A2-double-blind-randomised-clinical-trial
#8
Christian Kähler, Tadeusz Derezinski, Joanna Bocian-Sobkowska, Andrea Keckeis, Gabriele Zacke
BACKGROUND: The trial aimed to evaluate the efficacy and safety of Spicae aetheroleum (Spicae ae.), a phytomedicine obtained by steam distillation of the flowering tops of Lavandula latifolia, as compared to placebo in adult patients with acute bronchitis. METHODS: Patients with uncomplicated acute bronchitis (bronchitis severity score [BSS] ≥ 5 score points) were randomly assigned to treatment with Spicae ae. or placebo in a double-blind, parallel-group design...
December 5, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29190684/respiratory-syncytial-and-influenza-viruses-in-children-under-2-years-old-with-severe-acute-respiratory-infection-sari-in-maputo-2015
#9
Mirela Pale, Afonso Nacoto, Almiro Tivane, Neuza Nguenha, Loira Machalele, Félix Gundane, Délcio Muteto, Josina Chilundo, Sandra Mavale, Cynthia Semá-Baltazar, Germano Pires, Orvalho Augusto, Tufária Mussá, Eduardo Gudo
INTRODUCTION: Although respiratory syncytial virus (RSV) and influenza virus (influenza) infections are one of the leading causes of Severe Acute Respiratory Infections (SARI) and death in young children worldwide, little is known about the burden of these pathogens in Mozambique. MATERIAL AND METHODS: From January 2015 to January 2016, nasopharyngeal swabs from 450 children, aged ≤2 years, who had been admitted to the Pediatric Department of the Maputo Central Hospital (HCM) in Mozambique, suffering with SARI were enrolled and tested for influenza and RSV using a real-time PCR assay...
2017: PloS One
https://www.readbyqxmd.com/read/29186758/simultaneous-determination-of-multiple-classes-of-hydrophilic-and-lipophilic-components-in-shuang-huang-lian-oral-liquid-formulations-by-uplc-triple-quadrupole-linear-ion-trap-mass-spectrometry
#10
(no author information available yet)
The Shuang-Huang-Lian (SHL) oral liquid is a combined herbal prescription used in the treatment of acute upper respiratory tract infection, acute bronchitis and pneumonia. Multiple constituents are considered to be responsible for the therapeutic effects of SHL. However, the quantitation of the multi-components from multiple classes is still unsatisfactory because of the high complexity of constituents in SHL. In this study, an accurate, rapid, and specific UPLC-MS/MS method was established for simultaneous quantification of 18 compounds from multiple classes in SHL oral liquid formulations...
November 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29182756/acute-phase-proteins-and-stress-markers-in-the-immediate-response-to-a-combined-vaccination-against-newcastle-disease-and-infectious-bronchitis-viruses-in-specific-pathogen-free-spf-layer-chicks
#11
Haider Kaab, Maureen M Bain, Peter David Eckersall
Vaccination is an important tool in poultry health, but is itself a stressor often resulting in a reduction in feed intake, body weight gain, and nutrient digestibility. In other species, vaccination is associated with an immediate acute-phase response. As an important immune parameter, the circulating heterophil/lymphocyte (H/L) ratio is a well-recognized parameter of stress in poultry. In this study, the effects of a routinely used commercial poultry vaccine on the acute phase response (APR) and H/L ratios in specific pathogen-free (SPF) layer chicks was examined to determine if post vaccination (PV) stress and an APR occur...
November 22, 2017: Poultry Science
https://www.readbyqxmd.com/read/29139241/porcine-respiratory-disease-complex-after-the-introduction-of-h1n1-2009-influenza-virus-in-brazil
#12
R R Rech, D Gava, M C Silva, L T Fernandes, V Haach, J R Ciacci-Zanella, R Schaefer
From 2009 to 2015, 74 lungs from suckling (6.8%), nursing (70.3%), fattening (20.3%) pigs and pregnant sows (2.7%) with respiratory signs from pig farms in Southern Brazil were submitted to a diagnostic laboratory for necropsy and/or histologic examination and screening for respiratory agents by RT-qPCR, immunohistochemistry (IHC), virus isolation (VI) and subtyping for influenza A virus (IAV), IHC and nested PCR for Mycoplasma hyopneumoniae (Mhyo), PCR for porcine circovirus 2 (PCV2), RT-qPCR for porcine reproductive and respiratory syndrome virus (PRRSV) and bacterial culture...
November 14, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29128032/acute-effects-of-ambient-air-pollution-on-lower-respiratory-infections-in-hanoi-children-an-eight-year-time-series-study
#13
Nguyen Thi Trang Nhung, Christian Schindler, Tran Minh Dien, Nicole Probst-Hensch, Laura Perez, Nino Künzli
BACKGROUND: Lower respiratory diseases are the most frequent causes of hospital admission in children worldwide, particularly in developing countries. Daily levels of air pollution are associated with lower respiratory diseases, as documented in many time-series studies. However, investigations in low-and-middle-income countries, such as Vietnam, remain sparse. OBJECTIVE: This study investigated the short-term association of ambient air pollution with daily counts of hospital admissions due to pneumonia, bronchitis and asthma among children aged 0-17 in Hanoi, Vietnam...
January 2018: Environment International
https://www.readbyqxmd.com/read/29126755/-cannabis-and-lung-what-we-know-and-everything-we-don-t-know-yet
#14
REVIEW
T Urban, J Hureaux
Cannabis use increased sharply from 2010 to 2014 in France. Cannabis is often consumed with tobacco, although the use of marijuana is developing. Tobacco and cannabis smoke have many common characteristics in terms of irritants, carcinogens and carbon monoxide. They also differentiate by their dependence mechanisms, with nicotine and its receptors for tobacco and tetra-hydro-cannabinol (THC) and its specific receptors for cannabis. Chronic inhalation (700,000 daily users in France) over a long period most likely increases the relative risk of bronchial cancer...
November 7, 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/29122495/up-regulation-of-serum-periostin-and-squamous-cell-carcinoma-antigen-levels-in-infants-with-acute-bronchitis-due-to-respiratory-syncytial-virus
#15
Hiroaki Nakamura, Kenichi Akashi, Masako Watanabe, Shoichiro Ohta, Junya Ono, Yoshinori Azuma, Noriko Ogasawara, Keisuke Yamamoto, Norikazu Shimizu, Hiroyuki Tsutsumi, Kenji Izuhara, Toshio Katsunuma
BACKGROUND: Periostin and squamous cell carcinoma antigen (SCCA) are involved in the pathogenesis of asthma. Acute bronchitis due to respiratory syncytial virus (RSV) infection during infancy exhibits an asthma-like pathogenesis, suggesting that it may be associated with the subsequent development of asthma. However, the mechanism by which RSV infection leads to development of asthma has not yet been fully elucidated. METHODS: Infants younger than 36 months were enrolled and classified into three groups...
November 6, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29119851/clinical-characteristics-of-children-infected-with-enterovirus-d68-in-an-outpatient-clinic-and-the-association-with-bronchial-asthma
#16
Tsutomu Itagaki, Yoko Aoki, Yohei Matoba, Shizuka Tanaka, Tatsuya Ikeda, Katsumi Mizuta, Yoko Matsuzaki
BACKGROUND: All reports of increases in severe respiratory disease associated with human enterovirus D68 (EV-D68) are from hospital settings. However, there are few reports describing clinical characteristics in less severely affected populations. METHODS: We conducted a retrospective observational study from January 2010 to December 2015 in Yamagata, Japan. Using regional passive surveillance, 5794 respiratory specimens were collected from children who initially presented to an outpatient clinic with acute respiratory symptoms...
November 9, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/29119837/eps-7630-is-effective-and-safe-in-children-under-6-years-with-acute-respiratory-tract-infections-clinical-studies-revisited
#17
Wolfgang Kamin, Petra Funk, Georg Seifert, Andrea Zimmermann, Walter Lehmacher
Objective - Pelargonium sidoides preparation EPs 7630 has been proven safe and effective in acute respiratory tract infections (aRTIs), but data for young children have not been presented separately. We reviewed clinical studies and present an overview of known and newly analyzed data from children <6 years. Methods - We searched MEDLINE and EMBASE for interventional and non-interventional studies which investigated the effects of EPs 7630 in aRTIs and included children <6 years of age. Subgroup analyses for this age range were performed for symptom scales, global efficacy or effectiveness assessments, and safety outcomes...
November 9, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29118578/changes-in-definition-lead-to-changes-in-the-clinical-characteristics-across-copd-categories-according-to-gold-2017-a-national-cross-sectional-survey-in-china
#18
Lina Sun, Yahong Chen, Rui Wu, Ming Lu, Wanzhen Yao
Purpose: To investigate how the changes of definition in assessment of Global Initiative for Chronic Obstructive Lung Disease (GOLD) stratification 2017 lead to changes of chronic obstructive pulmonary disease (COPD) patient clinical characteristics across categories in China. Patients and methods: COPD patients from 11 medical centers in China were stratified into old and new groups A-D twice according to the GOLD 2011 and 2017 comprehensive assessment. Demography and clinical characteristics were compared between old and new groups A-D...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29090990/handgrip-strength-in-chronic-obstructive-pulmonary-disease-associations-with-acute-exacerbations-and-body-composition
#19
Carlos H Martinez, Alejandro A Diaz, Catherine A Meldrum, Merry-Lynn N McDonald, Susan Murray, Gregory L Kinney, John E Hokanson, Jeffrey L Curtis, Russell P Bowler, MeiLan K Han, George R Washko, Elizabeth A Regan
RATIONALE: Handgrip strength (HGS) predicts mortality in the elderly, but its determinants and clinical significance in chronic obstructive pulmonary disease (COPD) has not been defined. OBJECTIVES: We tested associations of HGS with pectoralis muscle area (PMA), subcutaneous adipose tissue (SAT), imaging characteristics, and lung function in smokers with COPD, and evaluated the cross-sectional and longitudinal associations of HGS with acute respiratory events. METHODS: We analyzed demographic, clinical, spirometry, HGS, and imaging data of 272 subjects with COPD, obtaining measures of airway thickness, emphysema, PMA, and SAT from chest computed tomography scans...
November 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29080708/classification-of-cough-as-a-symptom-in-adults-and-management-algorithms-chest-guideline-and-expert-panel-report
#20
Richard S Irwin, Cynthia L French, Anne B Chang, Kenneth W Altman
BACKGROUND: We performed systematic reviews using the population, intervention, comparison, outcome (PICO) format to answer the following key clinical question: Are the CHEST 2006 classifications of acute, subacute and chronic cough and associated management algorithms in adults that were based on durations of cough useful? METHODS: We used the CHEST Expert Cough Panel's protocol for the systematic reviews and the American College of Chest Physicians (CHEST) methodological guidelines and Grading of Recommendations Assessment, Development, and Evaluation framework...
November 10, 2017: Chest
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