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https://www.readbyqxmd.com/read/28213342/virtual-visits-for-acute-nonurgent-care-a-claims-analysis-of-episode-level-utilization
#1
Aliza S Gordon, Wallace C Adamson, Andrea R DeVries
BACKGROUND: Expansion of virtual health care-real-time video consultation with a physician via the Internet-will continue as use of mobile devices and patient demand for immediate, convenient access to care grow. OBJECTIVE: The objective of the study is to analyze the care provided and the cost of virtual visits over a 3-week episode compared with in-person visits to retail health clinics (RHC), urgent care centers (UCC), emergency departments (ED), or primary care physicians (PCP) for acute, nonurgent conditions...
February 17, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28192201/the-natural-product-bergenin-ameliorates-lipopolysaccharide-induced-acute-lung-injury-by-inhibiting-nf-kappab-activition
#2
Shengqian Yang, Ziru Yu, Lin Wang, Tianyi Yuan, Xue Wang, Xue Zhang, Jinhua Wang, Yang Lv, Guanhua Du
ETHNOPHARMACOLOGICAL RELEVANCE: Bergenin, an active constituent of the plants of the genus Bergenia, has been reported to have anti-inflammatory effects in the treatment of chronic bronchitis and chronic gastritis clinically. However, its therapeutic effect on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and its potential mechanisms of actions were still unkown. AIM OF THIS STUDY: This study aimed to evaluate the effect of bergenin on murine model of acute lung injury induced by LPS and also to explore its potential mechanisms...
February 9, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28168862/increased-systemic-cytokine-chemokine-expression-in-asthmatic-and-non-asthmatic-patients-with-bacterial-viral-or-mixed-lung-infection
#3
Maria J Giuffrida, Nereida Valero, Jesus Mosquera, Anyelo Duran, Francisco Arocha, Betulio Chacín, Luz Marina Espina, Jenifer Gotera, John Bermudez, Alibeth Mavarez, Melchor Alvarez-Mon
This study was aimed to determine the profiles of serum cytokines (IL-1β, TNF-α, IL-4, IL-5) and chemokines (MCP-1: monocyte chemoattract protein-1 and RANTES: regulated on activation normal T cell expressed and secreted) in individuals with an asthmatic versus a non-asthmatic background with bacterial, viral or mixed acute respiratory infection. Asthmatic (n=14) and non- asthmatic (n=29) patients with acute viral, bacterial or mixed (bacterial and viruses) respiratory infection were studied. Patients were also analyzed as individuals with pneumonia or bronchitis...
February 7, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28149969/6-steps-to-take-when-a-patient-insists-on-that-antibiotic
#4
EDITORIAL
John Hickner
Patients may be less likely to ask for an antibiotic if you refer to acute bronchitis as a "chest cold."
December 2016: Journal of Family Practice
https://www.readbyqxmd.com/read/28149573/current-situation-of-asthma-copd-overlap-syndrome-acos-in-chinese-patients-older-than-40-years-with-airflow-limitation-rationale-and-design-for-a-multicenter-cross-sectional-trial-study-protocol
#5
Jian Kang, Wanzhen Yao, Baiqiang Cai, Ping Chen, Xia Ling, Hongyan Shang
BACKGROUND: Asthma and chronic obstructive pulmonary disease (COPD) are the frequently occurring chronic airway diseases, and the overlapping syndrome observed in the majority of patients has been recently defined as asthma-COPD overlap syndrome (ACOS) by the Global Initiative for Chronic Obstructive Lung (GOLD, 2014) and Global initiative for Asthma (GINA, 2015). The proportion, features, and clinical practice of ACOS still remain elusive in China. We are conducting this multicenter, cross-sectional, observational study (NCT02600221) to investigate the distributions of chronic obstructive diseases in patients >40 years of age with chronic airflow limitation in China along with determination of the main clinical practice and features of these diseases...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28128095/antimicrobial-prescribing-patterns-in-a-large-tertiary-hospital-in-shanghai-china
#6
Yuan-Yuan Wang, Ping Du, Fang Huang, Dong-Jie Li, Jun Gu, Fu-Ming Shen, Yuan-Ying Jiang
Whilst the 'Principles of clinical use of antibiotics' was released by the Ministry of Health of the People's Republic of China in 2004, limited research has been conducted to evaluate the quality of antibiotic use in real-world practice. In this study, we sought to examine antimicrobial prescribing patterns in a large tertiary hospital in Shanghai, China. De-identified outpatient and emergency department pharmacy records containing antimicrobials were extracted from the hospital electronic health records system...
December 2016: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28122841/antibiotic-management-of-children-with-infectious-diseases-in-dutch-primary-care
#7
Anne R J Dekker, Theo J M Verheij, Alike W van der Velden
BACKGROUND: Childhood infections are common in general practice. Although clinical guidelines recommend restrictive antibiotic use for children, antibiotics are too often prescribed. OBJECTIVE: The aim of this study was to obtain insight in antibiotic prescribing for children related to clinical diagnoses. This is pivotal to define improvement strategies in the antibiotic management. METHODS: In this observational study, we used consultation data collected from 45 general practices in the Netherlands in 2012...
January 24, 2017: Family Practice
https://www.readbyqxmd.com/read/28119402/a-national-pharmacoepidemiological-study-of-antibiotic-use-in-korean-paediatric-outpatients
#8
Yun-Kyoung Song, Nayoung Han, Myeong Gyu Kim, Hyeu-Jin Chang, Hyun Soon Sohn, Eunhee Ji, Jung Mi Oh
BACKGROUND: Information on the use of antibiotics in Eastern Asian children is limited. The objectives of this study were to evaluate in Korean paediatric outpatients (1) the nationwide pattern of prescribing antibiotics according to age group and medical institution and (2) the adherence of antibiotic use for acute respiratory tract infections to both national guidelines and European antibiotic prescribing quality indicators. METHOD: This population-based study used the national insurance reimbursement database for 2011...
January 24, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28114931/procalcitonin-guided-diagnosis-and-antibiotic-stewardship-revisited
#9
REVIEW
Ramon Sager, Alexander Kutz, Beat Mueller, Philipp Schuetz
Several controlled clinical studies have evaluated the potential of the infection biomarker procalcitonin (PCT) to improve the diagnostic work-up of patients with bacterial infections and its influence on decisions regarding antibiotic therapy. Most research has focused on lower respiratory tract infections and critically ill sepsis patients. A clinical utility for PCT has also been found for patients with urinary tract infections, postoperative infections, meningitis, and patients with acute heart failure with possible superinfection (i...
January 24, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28092467/early-investigational-antibiotics-for-the-treatment-of-acute-exacerbations-of-chronic-bronchitis
#10
Matthew E Falagas, Maria Georgiou
Acute exacerbations in patients with chronic bronchitis are a leading cause of hospitalizations and death. Bacteria contribute significantly to such exacerbations. The aim of this review was to explore the potential role of investigational antibiotics in the treatment of these episodes. Areas covered: The available literature in PubMed database, in websites related to investigational drugs and in websites of the producing companies has been searched. The in vitro activity against pathogens involved in acute exacerbations of chronic bronchitis and the pharmacokinetic profile of antibiotics currently under development were taken into consideration for inclusion in the review...
March 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/28089914/arachidonic-acid-with-taurine-enhances-pulmonary-absorption-of-macromolecules-without-any-serious-histopathological-damages
#11
Masateru Miyake, Takanori Minami, Hiroyuki Yamazaki, Chie Emoto, Tadashi Mukai, Hajime Toguchi
Therapeutic peptides and protein are being used in several indications; however, their poor permeability still remains to be solved. This study focused on the pulmonary route of macromolecules. First, the effects of arachidonic acid (AA) as an absorption enhancer on drug serum concentration, after intratracheal administration, were investigated in rats. Second, the safety of AA was assessed in rats in an acute toxicity study for 7 days. AA enhanced the exposure of both interferon-α (IFN-α) and fluorescein isothiocyanate 4000 (FD-4)...
January 13, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28088130/vaccine-candidates-against-nontypeable-haemophilus-influenzae-a-review
#12
REVIEW
Ava Behrouzi, Farzam Vaziri, Fatemeh Rahimi-Jamnani, Parviz Afrough, Mohammad Rahbar, Fereshteh Satarian, Seyed Davar Siadat
Nonencapsulated, nontypeable Hemophilus influenzae (NTHi) remains an important cause of acute otitis and respiratory diseases in children and adults. NTHi bacteria are one of the major causes of respiratory tract infections, including acute otitis media, cystic fibrosis, and community-acquired pneumonia among children, especially in developing countries. The bacteria can also cause chronic diseases such as chronic bronchitis and chronic obstructive pulmonary disease in the lower respiratory tract of adults...
2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/28067786/impact-of-air-pollutants-on-outpatient-visits-for-acute-respiratory-outcomes
#13
Ran Li, Ning Jiang, Qichen Liu, Jing Huang, Xinbiao Guo, Fan Liu, Zhancheng Gao
The air pollution in China is a severe problem. The aim of our study was to investigate the impact of air pollutants on acute respiratory outcomes in outpatients. Outpatient data from 2 December 2013 to 1 December 2014 were collected, as well as air pollutant data including ozone (O₃), nitrogen dioxide (NO₂), carbon monoxide (CO), sulfur dioxide (SO₂), and particulate matter (PM2.5 and PM10). We screened six categories of acute respiratory outcomes and analyzed their associations with different air pollutant exposures, including upper respiratory tract infection (URTI), acute bronchitis (AB), community-acquired pneumonia (CAP), acute exacerbation of chronic obstructive pulmonary disease (AECOPD), acute exacerbation of asthma (AE-asthma), and acute exacerbation of bronchiectasis (AEBX)...
January 5, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28018766/differentiation-of-lung-cancer-empyema-and-abscess-through-the-investigation-of-a-dry-cough
#14
Brittany Urso, Scott Michaels
An acute dry cough results commonly from bronchitis or pneumonia. When a patient presents with signs of infection, respiratory crackles, and a positive chest radiograph, the diagnosis of pneumonia is more common. Antibiotic failure in a patient being treated for community-acquired pneumonia requires further investigation through chest computed tomography. If a lung mass is found on chest computed tomography, lung empyema, abscess, and cancer need to be included on the differential and managed aggressively. This report describes a 55-year-old Caucasian male, with a history of obesity, recovered alcoholism, hypercholesterolemia, and hypertension, presenting with an acute dry cough in the primary care setting...
November 24, 2016: Curēus
https://www.readbyqxmd.com/read/27986496/medical-diagnostics-for-indoor-mold-exposure
#15
REVIEW
Julia Hurraß, Birger Heinzow, Ute Aurbach, Karl-Christian Bergmann, Albrecht Bufe, Walter Buzina, Oliver A Cornely, Steffen Engelhart, Guido Fischer, Thomas Gabrio, Werner Heinz, Caroline E W Herr, Jörg Kleine-Tebbe, Ludger Klimek, Martin Köberle, Herbert Lichtnecker, Thomas Lob-Corzilius, Rolf Merget, Norbert Mülleneisen, Dennis Nowak, Uta Rabe, Monika Raulf, Hans Peter Seidl, Jens-Oliver Steiß, Regine Szewszyk, Peter Thomas, Kerttu Valtanen, Gerhard A Wiesmüller
In April 2016, the German Society of Hygiene, Environmental Medicine and Preventative Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin (GHUP)) together with other scientific medical societies, German and Austrian medical societies, physician unions and experts has provided an AWMF (Association of the Scientific Medical Societies) guideline 'Medical diagnostics for indoor mold exposure'. This guideline shall help physicians to advise and treat patients exposed indoors to mold. Indoor mold growth is a potential health risk, even without a quantitative and/or causal association between the occurrence of individual mold species and health effects...
December 5, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27976136/ivy-leaf-extract-ea-575%C3%A2-in-daily-practice-treatment-of-acute-bronchitis-in-schoolchildren
#16
C Staiger, C Lang, T Wegener
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27974570/channel-inactivating-mutations-and-their-revertant-mutants-in-the-envelope-protein-of-the-infectious-bronchitis-virus
#17
Janet To, Wahyu Surya, To Sing Fung, Yan Li, Carmina Verdià-Bàguena, Maria Queralt-Martin, Vicente M Aguilella, Ding Xiang Liu, Jaume Torres
: It has been shown previously in the severe acute respiratory syndrome coronavirus (SARS-CoV) that two point mutations, N15A and V25F, in the transmembrane domain (TMD) of the envelope (E) protein abolished channel activity and led to in vivo attenuation. Pathogenicity was recovered in mutants that also regained E protein channel activity. In particular, V25F was rapidly compensated by changes at multiple V25F-facing TMD residues located on a neighboring monomer, consistent with a recovery of oligomerization...
December 14, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27966195/beyond-bronchitis-a-review-of-the-congenital-and-acquired-abnormalities-of-the-bronchus
#18
REVIEW
Thomas Marini, Susan K Hobbs, Abhishek Chaturvedi, Kathrine Kaproth-Joslin
Anomalies of the bronchus can be both congenital and acquired. Several different congenital aberrations of the bronchial anatomy are commonly encountered including tracheal bronchus, accessory cardiac bronchus, and bronchial agenesis/aplasia/hypoplasia. In addition, Williams-Campbell syndrome and cystic fibrosis are two other congenital conditions that result in bronchial pathology. Acquired pathology affecting the bronchi can typically be divided into three broad categories of bronchial disease: bronchial wall thickening, dilatation/bronchiectasis, and obstruction/stenosis...
February 2017: Insights Into Imaging
https://www.readbyqxmd.com/read/27956842/role-of-a-proprietary-propolis-based-product-on-the-wait-and-see-approach-in-acute-otitis-media-and-in-preventing-evolution-to-tracheitis-bronchitis-or-rhinosinusitis-from-nonstreptococcal-pharyngitis
#19
Francesco Di Pierro, Alberto Zanvit, Maria Colombo
Antipyretics and/or anti-inflammatory drugs along with a wait-and-see approach are the only treatments recommended in early acute otitis media (AOM) or viral pharyngitis. Propolis has been widely investigated for its antibacterial, antiviral, and anti-inflammatory properties and could perhaps be administered as an add-on therapy during watchful waiting in AOM or for better control of symptoms in nonstreptococcal pharyngitis. However, propolis has well-known problems of poor solubility and low oral bioavailability...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27956716/therapeutic-potential-of-medicinal-plants-and-their-constituents-on-lung-inflammatory-disorders
#20
REVIEW
Hyun Pyo Kim, Hyun Lim, Yong Soo Kwon
Acute bronchitis and chronic obstructive pulmonary diseases (COPD) are essentially lung inflammatory disorders. Various plant extracts and their constituents showed therapeutic effects on several animal models of lung inflammation. These include coumarins, flavonoids, phenolics, iridoids, monoterpenes, diterpenes and triterpenoids. Some of them exerted inhibitory action mainly by inhibiting the mitogen-activated protein kinase pathway and nuclear transcription factor-κB activation. Especially, many flavonoid derivatives distinctly showed effectiveness on lung inflammation...
December 16, 2016: Biomolecules & Therapeutics
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