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Calcium acetate

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https://www.readbyqxmd.com/read/29452584/high-phosphorus-intake-and-gut-related-parameters-results-of-a-randomized-placebo-controlled-human-intervention-study
#1
Ulrike Trautvetter, Amélia Camarinha-Silva, Gerhard Jahreis, Stefan Lorkowski, Michael Glei
BACKGROUND: In recent years, high phosphate intakes were discussed critically. In the small intestine, a part of the ingested phosphate and calcium precipitates to amorphous calcium phosphate (ACP), which in turn can precipitate other intestinal substances, thus leading to a beneficial modulation of the intestinal environment. Therefore, we analysed faecal samples obtained from a human intervention study regarding gut-related parameters. METHODS: Sixty-two healthy subjects (men, n = 30; women, n = 32) completed the double-blind, placebo-controlled and parallel designed study (mean age: 29 ± 7 years; mean BMI: 24 ± 3 kg/m 2 )...
February 16, 2018: Nutrition Journal
https://www.readbyqxmd.com/read/29447949/protective-effects-of-alpinae-oxyphyllae-fructus-extracts-on-lipopolysaccharide-induced-animal-model-of-alzheimer-s-disease
#2
Yunlong Wang, Mengshi Wang, Kaiyue Fan, Tongde Li, Tingxu Yan, Bo Wu, Kaishun Bi, Ying Jia
ETHNOPHARMACOLOGICAL RELEVANCE: Alpinae Oxyphyllae Fructus (AOF) with warming and tonifying the kidney and spleen, anti-salivation, anti-polyuria and anti-diarrhea functions is the dried ripe fruits of Alpinia oxyphylla Miq. (Zingiberaceae). As a traditional Chinese medicine, its application history is very long. AIMS OF THE STUDY: The purpose of our study is to investigate the effects of different solvent extracts from AOF on lipopolysaccharide (LPS)-induced animal model of Alzheimer's disease (AD) to elucidate the traditional medical theories with modern pharmacological methods and provide a reference for further clarifying its active components and mechanisms...
February 12, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29423026/effect-of-calcium-salt-of-long-chain-fatty-acids-and-alfalfa-supplementation-on-performance-of-holstein-bulls
#3
Yang He, Wenjing Niu, Qinghua Qiu, Chuanqi Xia, Taoqi Shao, Haibo Wang, Qianwen Li, Zhantao Yu, Zhibiao Gao, Muhammad Aziz Ur Rahman, Huawei Su, Binghai Cao
The purpose of this study was to assess the effects of calcium salt of long-chain fatty acids (CSFA) and alfalfa on beef cattle in the late fattening. 48 Holstein bulls were selected and randomly divided into 4 groups, feeding four dietary that Leymus chinensis with (LC) or with no (LN) 2.4% CSFA, and alfalfa replaced 50% Leymus chinensis with (AC) or with no (AN) 2.4% CSFA. The results indicated that alfalfa improved the feed conversion rate (P < 0.05). CSFA increased serum low density lipoprotein cholesterol, and reduced the cooking loss of Longissimus muscle (P < 0...
January 9, 2018: Oncotarget
https://www.readbyqxmd.com/read/29420995/cysteine-ameliorates-allergic-inflammatory-reactions-by-suppressing-thymic-stromal-lymphopoietin-production-in-activated-human-mast-cells
#4
Sun-Young Nam, Hyung-Min Kim, Hyun-Ja Jeong
Thymic stromal lymphopoietin (TSLP) derived by mast cells is recognized as a critical factor in many allergic inflammatory disorders. Cysteine is a well-known amino acid which exhibits anti-inflammatory activities. However, the effect and mechanism of cysteine on TSLP production have not been investigated. Thus, we hypothesized that cysteine may regulate TSLP production from mast cells. To test this hypothesis, the anti-inflammatory effects and signaling pathways of cysteine were investigated in phorbol 12-myristate 13-acetate 4 and calcium ionophore A23187 (PMACI)-stimulated human mast cell line HMC-1...
January 2018: Nutrition Research
https://www.readbyqxmd.com/read/29419708/intravenous-calcium-zinc-diethylene-triamine-penta-acetic-acid-in-patients-with-presumed-gadolinium-deposition-disease-a-preliminary-report-on-25-patients
#5
Richard C Semelka, Miguel Ramalho, Michael Jay, Lisa Hickey, Joseph Hickey
OBJECTIVES: The aim of this study was to report the use of intravenous calcium (Ca)-/zinc (Zn)-diethylene triamine penta-acetic acid (DTPA) for the treatment of 25 symptomatic patients diagnosed with gadolinium deposition disease (GDD). MATERIALS AND METHODS: Written informed consent was obtained. Twenty-five patients (18 women; mean age, 46.8 ± 15.3 years) with a diagnosis of GDD were included. All patients had received at least 1 administration of a gadolinium (Gd)-based contrast agent...
February 6, 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29406482/randomized-double-blinded-sham-controlled-split-hand-trial-evaluating-the-safety-and-efficacy-of-triamcinolone-acetate-injection-after-calcium-hydroxylapatite-volume-restoration-of-the-dorsal-hand
#6
Douglas C Wu, Mitchel P Goldman
BACKGROUND: Calcium hydroxylapatite (CaHA) is currently the only FDA-approved soft-tissue filler indicated for augmentation of the dorsal hand. Although the treatment is generally safe and effective, adverse side effects such as swelling and edema postinjection are common and can sometimes be debilitating. OBJECTIVE: In this study, the authors explore the utility of triamcinolone acetate coinjection with CaHA to the dorsal hands to mitigate adverse effects and improve patient experience...
February 5, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29398679/azelnidipine-inhibits-the-differentiation-and-activation-of-thp-1-macrophages-through-the-l-type-calcium-channel
#7
Hiroshi Komoda, Aya Shiraki, Jun-Ichi Oyama, Toshiyuki Nishikido, Koichi Node
AIM: Recently, calcium channel blockers (CCBs) have been reported to reduce atherosclerosis with anti-inflammatory or antiatherosclerotic effects in vivo. It is well established that monocytes and macrophages play important roles in promoting atherosclerosis. However, the effects of CCBs on macrophage activation remain unclear. The aim of this study was to evaluate the effects of azelnidipine, a dihydropyridine L-type CCB, on the activation of macrophages and to clarify the mechanisms of the effects of CCBs on atherosclerosis...
February 3, 2018: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29386969/nutritional-compositions-and-antiproliferative-activities-of-different-solvent-fractions-from-ethanol-extract-of-cyphomandra-betacea-tamarillo-fruit
#8
Maisarah Abdul Mutalib, Asmah Rahmat, Faisal Ali, Fauziah Othman, Rajesh Ramasamy
Background: This study aims to examine various solvent extracts of Cyphomandra betacea (tamarillo) also known as the tree tomato, for their bioactive constituents and antioxidant activity. The study also aims to examine its effect on cancer cell death using two types of cancer cell lines (liver and breast cancer cell). Methods: The first part of the study evaluates the nutritional composition of tamarillo. Then, phytochemical profiling using GC-MS analysis in ethanolic tamarillo extract was conducted...
October 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/29380901/the-influence-of-agents-differentiating-hl-60-cells-toward-granulocyte-like-cells-on-their-ability-to-release-neutrophil-extracellular-traps
#9
Aneta Manda-Handzlik, Weronika Bystrzycka, Małgorzata Wachowska, Sandra Sieczkowska, Anna Stelmaszczyk-Emmel, Urszula Demkow, Olga Ciepiela
Studies on neutrophil extracellular traps (NETs) are challenging as neutrophils live shortly and easily become activated. Thus, availability of a cell line model closely resembling the functions of peripheral blood neutrophils would be advantageous. Our purpose was to find a compound that most effectively differentiates HL-60 (human promyelocytic leukemia) cells toward granulocyte-like cells able to release NETs. HL-60 cells were differentiated with all-trans retinoic acid (ATRA), dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) and stimulated with phorbol 12-myristate 13-acetate (PMA) or calcium ionophore A23187 (CI)...
January 30, 2018: Immunology and Cell Biology
https://www.readbyqxmd.com/read/29355453/critical-factors-affecting-ethanol-production-by-immobilized-pichia-stipitis-using-corn-cob-hemicellulosic-hydrolysate
#10
Mohan Kashid, Anand Ghosalkar
Fermentation of xylose from hydrolysate of acid treated corn cob by Pichia stipitis is inhibited by acetic acid and lignin derivatives. In the present study we have designed and implemented an immobilized cell culture for xylose to ethanol conversion from acid treated corn cob hydrolysate without removal of fermentation inhibitors. In this study, cultivations of suspended and immobilized Pichia were compared in terms of ethanol yield and productivity to investigate whether the cell immobilization could improve resistance to inhibitors...
January 22, 2018: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/29353067/antinociception-of-the-spirocyclopiperazinium-salt-compound-lxm-15-via-activating-%C3%AE-7-nachr-and-m4-machr-and-inhibiting-camkii%C3%AE-camp-creb-cgrp-signalling-pathway-in-mice
#11
Hua Yang, Qi Sun, Yingying Liang, Yimin Jiang, Runtao Li, Jia Ye
The aim of this study was to investigate the analgesic effect of the spirocyclopiperazinium salt compound LXM-15 by intragastric administration in thermal and chemical pain models and further to elucidate the possible molecular mechanisms. The results showed that LXM-15 exerted significant antinociception in hot-plate test, formalin test and acetic acid writhing test. Western blot analysis showed that LXM-15 significantly reduced the upregulation of phosphorylation of calcium/calmodulin -dependent protein kinaseⅡα (CaMKIIα) and cAMP response element-binding protein (CREB), and further decreased the elevation of calcitonin gene related peptide (CGRP) in the dorsal root ganglion (DRG) and spinal cord in mice...
January 15, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29343451/biochemical-characterization-of-halophilic-alkalithermophilic-amylopullulanase-puld7-and-truncated-amylopullulanases-puld7%C3%AE-n-and-puld7%C3%AE-c
#12
Noha M Mesbah, Juergen Wiegel
A pullulanase, PulD7, was identified in the genome of the halophilic, alkalithermophilic isolate Alkalilimnicola sp. NM-DCM-1. PulD7 is 701 amino acids large with a carbohydrate binding module (CBM) 48 at the N-terminal. The full length PulD7 and N- and C-terminal truncated versions were cloned, heterologously expressed and functionally characterized. PulD7 displayed maximal activity at 55 °C, pH 9.5 and 2 M NaCl. PulD7 had good thermal stability, with a half-life of 693 min at 50 °C. PulD7 is an amylopullulanase, hydrolyzing both α‑1,4‑ and α‑1,6‑glycosidic bonds in soluble starch and pullulan, respectively...
January 14, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29279577/characterization-of-anti-ice-nucleation-activity-of-the-extract-from-coffee-refuse
#13
Hidehisa Kawahara, Eri Tagawa, Chihiro Watanabe, Jun Hamada, Sayaka Hamada
 The supercooling-facilitating (SCF) activities, that is, the anti-ice nucleation activity of the hot water extracts from five types of processed food refuse was examined. The extract with the highest activity among five hot water extracts was coffee refuse, showing 1.50℃ of SCF activity at a final concentration of 0.1 mg/ml. From the hot water extract of coffee refuse, the coffee refuse extract containing various polyphenols was prepared by the ultrafiltration (less than MWCO 10,000), a solvent fractionation of ethyl acetate...
2017: Biocontrol Science
https://www.readbyqxmd.com/read/29225247/hypercalcemia-after-the-discontinuation-of-medroxyprogesterone-acetate
#14
Erina Yuasa-Shibasaki, Sumiyasu Ishii, Shunichi Matsumoto, Takuya Tomaru, Kazuhiko Horiguchi, Aya Osaki, Atsushi Ozawa, Nobuyuki Shibusawa, Tetsurou Satoh, Masanobu Yamada
A 39-year-old woman was admitted to our hospital with symptoms of general fatigue, nausea, and vomiting that appeared three months after she stopped seven years of medroxyprogesterone acetate (MPA) medication for endometrial stromal sarcoma. Laboratory tests demonstrated moderate hypercalcemia. Several tests demonstrated that she was suffering from adrenal insufficiency. Glucocorticoid supplementation decreased her calcium level to a normal range, indicating that hypercalcemia was induced by adrenal insufficiency...
December 8, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29192681/edta-chelation-for-symptomatic-band-keratopathy-results-and-recurrence
#15
A Al-Hity, K Ramaesh, D Lockington
PurposeTo identify causes of symptomatic band keratopathy, and assess the results and long-term recurrence rates following chelation with topical ethylene-diamine-tetra-acetic acid (EDTA).Patients and methodsA retrospective review of surgical logbooks identified patients managed by EDTA chelation for symptomatic band keratopathy from 2009 to 2015.ResultsWe identified 108 cases; 89 case notes were available for analysis. Most cases of band keratopathy were idiopathic (36%). The most commonly identified underlying diagnosis was long-term topical glaucoma therapy (27%)...
December 1, 2017: Eye
https://www.readbyqxmd.com/read/29182665/the-role-of-protease-inhibitors-on-the-remineralization-of-demineralized-dentin-using-the-pilp-method
#16
Hamid Nurrohman, Karina M M Carneiro, John Hellgeth, Kuniko Saeki, Sally J Marshall, Grayson W Marshall, Stefan Habelitz
Mineralized and sound dentin matrices contain inactive preforms of proteolytic enzymes that may be activated during the demineralization cycle. In this study, we tested the hypothesis that protease inhibitors (PI) preserve demineralized collagen fibrils and other constituents of the dentin matrix and thereby affect the potential for remineralization. Artificial carious lesions with lesion depths of 140 μm were created with acetate buffer (pH = 5.0, 66 hours), and remineralized using a polymer-induced-liquid-precursor (PILP) process (pH = 7...
2017: PloS One
https://www.readbyqxmd.com/read/29181825/a-primary-hepatic-gastrinoma-accompanied-by-hyperplasia-of-multi-nodular-brunner-s-glands
#17
Takaomi Hagi, Yohei Hosoda, Izumi Komoto, Shinji Uemoto, Susumu Hijioka, Yoshiro Taki, Kazuhiro Nishiyama, Masayuki Imamura
BACKGROUND: Primary hepatic gastrinoma causing severe ulcerogenic syndrome is extremely rare. Herein, we report a case of primary hepatic gastrinoma accompanied by hyperplasia of multi-nodular Brunner's glands in a patient who instead, preoperatively, was suspected of having multiple duodenal gastrinomas and hepatic metastasis. CASE PRESENTATION: A 57-year-old woman consulted a clinic complaining of melena, intermittent abdominal pain, diarrhea, and vomiting which had persisted for about 3 years...
November 28, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29178705/effectiveness-of-dentifrices-with-new-formulations-for-the-treatment-of-dentin-hypersensitivity-a-meta-analysis
#18
Christina Grünberg, Florian Bauer, Alexander Crispin, Michael Jakob, Reinhard Hickel, Miriam E Draenert
PURPOSE: This meta-analysis was conducted to evaluate if strontium-acetate- and arginine-containing dentifrices can significantly reduce dentin hypersensitivity (DH). METHODS: A systematic literature search was performed. The investigation period was from 2006 to 2015 with the search term "dentin hypersensitivity". Nine original articles were relevant. A network meta-analysis of combined z scores was performed. Pooled results from random effects models with their 95% confidence intervals are reported...
August 2017: American Journal of Dentistry
https://www.readbyqxmd.com/read/29172841/anti-inflammatory-effects-of-artemisia-scoparia-and-its-active-constituent-3-5-dicaffeoyl-epi-quinic-acid-against-activated-mast-cells
#19
Sun-Young Nam, Na-Ra Han, So-Young Rah, Youngwan Seo, Hyung-Min Kim, Hyun-Ja Jeong
OBJECTIVES: Artemisia scoparia Waldst. et Kit. (AS) has been used to treat inflammation, urticaria and hepatitis. However, the scientific studies of AS and its active compound for inflammatory reactions in activated human mast cell line, HMC-1 cells have not yet been elucidated. MATERIALS AND METHODS: Here, we isolated 3,5-dicaffeoyl-epi-quinic acid (DEQA) from AS butanol fraction. The anti-inflammatory effect of AS and its new active compound, DEQA was examined in HMC-1 cells by studying the following markers: phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-induced thymic stromal lymphopoietin (TSLP), tumor necrosis factor (TNF)-α, interleukin (IL)-1β and IL-6 secretion and mRNA expression by ELISA and RT-PCR, respectively...
November 27, 2017: Immunopharmacology and Immunotoxicology
https://www.readbyqxmd.com/read/29161660/molecular-mechanisms-of-anti-inflammatory-effect-of-chrysophanol-an-active-component-of-ast2017-01-on-atopic-dermatitis-in-vitro-models
#20
Hyun-Ja Jeong, Hee-Yun Kim, Hyung-Min Kim
AST2017-01 mainly consists of Rumex crispus and -Cordyceps militaris and has been widely consumed as an herbal medicine or functional food in Korea. Here we investigated the influences of AST2017-01 and its active component, chrysophanol on human mast cell (HMC-1 cell) and human keratinocyte (HaCaT cell)-mediated inflammatory reactions. Pretreatment with AST2017-01 or chrysophanol suppressed intracellular calcium levels and histamine release in phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-treated HMC-1 cells...
November 18, 2017: International Immunopharmacology
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