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Calcium acetate

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https://www.readbyqxmd.com/read/28639010/modulation-of-calcium-carbonate-precipitation-by-exopolysaccharide-in-bacillus-sp-jh7
#1
Hyun Jung Kim, Bora Shin, Yun Suk Lee, Woojun Park
Extracellular polymeric substance (EPS) is proposed to facilitate calcium ion supersaturation through its nucleation effect during the microbially induced calcium carbonate precipitation (MICP) process. However, the supersaturation effect of Ca(2+) via EPS in MICP has not been clearly demonstrated. Enhanced exopolysaccharide production of the alkali- and halotolerant MICP-capable bacteria, Bacillus sp. JH7, was achieved through glycerol addition. This was demonstrated by measuring cellular precipitation and Congo red binding...
June 22, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28616734/di-2-pyridylketone-4-4-dimethyl-3-thiosemicarbazone-dp44mt-an-anticancer-agent-exerts-an-anti-inflammatory-effect-in-activated-human-mast-cells
#2
Sun-Young Nam, Na-Ra Han, Kyoung Wan Yoon, Hyung-Min Kim, Hyun-Ja Jeong
OBJECTIVE: Inflammation has been closely associated with the development and progression of cancer. Previously, we reported that mast cells play a critical role in tumor growth. The purpose of this study is to investigate the anti-inflammatory effect of an anticancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), on an activated human mast cell line, in this case HMC-1 cells. METHODS: We evaluated the effect and specific molecular mechanism of Dp44mT on phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI) using HMC-1 cells...
June 14, 2017: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/28614613/population-pharmacokinetic-and-exposure-response-analysis-of-weekly-teriparatide-in-osteoporosis-patients
#3
Atsushi Ose, Masashi Serada, Keiko Yamashita, Kazuyuki Tsurui, Yusuke Tanigawara
Teriparatide is a potent therapeutic agent for the treatment of osteoporosis. One of the aims of this analysis was to develop a population pharmacokinetic (PPK) model to understand the pharmacokinetic characteristics of the once-weekly formulation of teriparatide. Another aim was to develop an exposure-response model to describe the relationship between change in bone mineral density (BMD) and teriparatide exposure after weekly subcutaneous administration. The PPK analysis showed that apparent total body clearance was significantly influenced by estimated creatinine clearance and the presence of osteoporosis...
June 14, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28598364/isoprenoids-production-from-lipid-extracted-microalgal-biomass-residues-using-engineered-e-coli
#4
Sumeng Wang, Jianming Yang
Microalgae are recognized as a third generation feedstock for biofuel production due to their rapid growth rates and lignin-free characteristics. In this study, a lipid extracted microalgal biomass residues was used as the raw material to produce isoprene, α-pinene and β-pinene with an engineered E. coli strain. We adopted an optimal sulfuric acid hydrolysis method (1:7 ratio of solid to acid solution, 32% (w/v) concentration of sulfuric acid solution at 90 °C for 90 min) to efficiently convert holocellulose into glucose efficiently (6...
June 9, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28585818/oxidation-of-secondary-methyl-ethers-to-ketones
#5
Pieter J Gilissen, Daniel Blanco-Ania, Floris P J T Rutjes
We present a mild way of converting secondary methyl ethers into ketones using calcium hypochlorite in aqueous acetonitrile with acetic acid as activator. The reaction is compatible with various oxygen- and nitrogen-containing functional groups and afforded the corresponding ketones in up to 98% yield. The use of this methodology could expand the application of the methyl group as a useful protecting group.
June 12, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28584909/a-review-of-phosphate-binders-in-chronic-kidney-disease-incremental-progress-or-just-higher-costs
#6
REVIEW
Wendy L St Peter, Lori D Wazny, Eric Weinhandl, Katie E Cardone, Joanna Q Hudson
As kidney disease progresses, phosphorus retention also increases, and phosphate binders are used to treat hyperphosphatemia. Clinicians prescribe phosphate binders thinking that reducing total body burden of phosphorus may decrease risks of mineral and bone disorder, fractures, cardiovascular disease, progression of kidney disease, and mortality. Recent meta-analyses suggest that sevelamer use results in lower mortality than use of calcium-containing phosphate binders. However, studies included in meta-analyses show significant heterogeneity, and exclusion or inclusion of specific studies alters results...
June 5, 2017: Drugs
https://www.readbyqxmd.com/read/28578568/calcium-l-lactate-frameworks-as-naturally-degradable-carriers-for-pesticides
#7
Jingjing Yang, Christopher A Trickett, Salman B Alahmadi, Ahmad S Alshammari, Omar M Yaghi
Two porous, chiral metal-organic frameworks (MOFs), Ca14(l-lactate)20(acetate)8(C2H5OH)(H2O) (MOF-1201) and Ca6(l-lactate)3(acetate)9(H2O) (MOF-1203), are constructed from Ca(2+) ions and l-lactate [CH3CH(OH)COO(-)], where Ca(2+) ions are bridged by the carboxylate and hydroxyl groups of lactate and the carboxylate group of acetate to give a three-dimensional arrangement of Ca(-COO, -OH) polyhedra supporting one-dimensional pores with apertures and internal diameters of 7.8 and 9.6 Å (MOF-1201) and 4.6 and 5...
June 21, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28572961/development-and-evaluation-of-floating-alginate-microspheres-for-oral-delivery-of-anthocyanins-a-preliminary-investigation
#8
Giovana B Celli, Amyl Ghanem, Marianne S Brooks
The goal of this study was to develop floating microspheres that could be used as gastroretentive systems for the delivery of anthocyanins (ACNs). These compounds are absorbed in the stomach and small intestine, and insufficient residence time in these organs could result in limited absorption and contribute to degradation. The microparticles containing freeze-dried haskap berry extract (321.96 ± 8.35 mg cyanidin 3-glucoside equivalents per g) were prepared by ionotropic gelation of alginate (9%, w/w) with calcium ions (CaCl2 at 2%, w/v) in the gelation bath, with calcium carbonate as the gas-generating compound (added at different ratios in the alginate/extract mixture)...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28560646/synergistic-effect-of-chryseobacterium-gleum-sp-suk-with-acc-deaminase-activity-in-alleviation-of-salt-stress-and-plant-growth-promotion-in-triticum-aestivum-l
#9
Komal K Bhise, Prashant K Bhagwat, Padma Babulal Dandge
Soil salinity is major abiotic stresses affecting morphological, biochemical and physiological processes of plant growth. Chryseobacterium gleum sp. SUK isolated from salt-stressed soil exhibited ACC (1-aminocyclopropane-1-carboxylate) deaminase activity with IAA (indole acetic acid), siderophore, ammonia, hydrogen cyanide production, 2% salt tolerance and fungal cell wall degrading enzyme production (cellulase, protease). The isolate also showed a poultry feather degrading activity which is the main waste material of poultry industry and opulent source of proteins, amino acids, nitrogen, phosphorous, calcium, potassium, manganese, zinc and copper...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28554984/the-effect-of-deoxycholic-acid-on-secretion-and-motility-in-the-rat-and-guinea-pig-large-intestine
#10
Nam Hee Kim, Jung Ho Park, Jae-Soon Park, Yeun-Ho Joung
Background/Aims: Bile acid is an important luminal factor that affects gastrointestinal motility and secretion. We investigated the effect of bile acid on secretion in the proximal and distal rat colon and coordination of bowel movements in the guinea pig colon. Methods: The short-circuit current from the mucosal strip of the proximal and distal rat colon was compared under control conditions after induction of secretion with deoxycholic acid (DCA) as well as after inhibition of secretion with indomethacin, 1,2-bis (o-aminophenoxy) ethane-N, N,N',N'-tetra-acetic acid (an intracellular calcium chelator; BAPTA), and tetrodotoxin (TTX) using an Ussing chamber...
May 29, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28544090/functional-tuning-of-the-catalytic-residue-pka-in-a-de-novo-designed-esterase
#11
Katharina Hiebler, Zsófia Lengyel, Carlos A Castañeda, Olga V Makhlynets
AlleyCatE is a de novo designed esterase that can be allosterically regulated by calcium ions. This artificial enzyme has been shown to hydrolyze p-nitrophenyl acetate (pNPA) and 4-nitrophenyl-(2-phenyl)-propanoate (pNPP) with high catalytic efficiency. AlleyCatE was created by introducing a single histidine residue (His(144) ) into a hydrophobic pocket of calmodulin. In this work, we explore the determinants of catalytic properties of AlleyCatE. We obtained the pKa value of the catalytic histidine using experimental measurements by NMR and pH rate profile and compared these values to those predicted from electrostatics pKa calculations (from both empirical and continuum electrostatics calculations)...
May 24, 2017: Proteins
https://www.readbyqxmd.com/read/28539709/multipathway-integrated-adjustment-mechanism-of-glycyrrhiza-triterpenes-curing-gastric-ulcer-in-rats
#12
Ying Wang, Shuai Wang, Yongrui Bao, Tianjiao Li, Xin Chang, Guanlin Yang, Xiansheng Meng
BACKGROUND: Gastric ulcer is a common chronic disease in human digestive system, which is difficult to cure, easy to relapse, and endangers human health seriously. Compared with western medicine, traditional Chinese medicine has a unique advantage in improving the general situation, stablizing medical condition, and with little side effects. Glycyrrhiza known as "king of all the medicine", has a range of pharmacological activities and is commonly used in a variety of proprietary Chinese medicines and formulations...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28532001/apatite-grown-in-niobium-by-two-step-plasma-electrolytic-oxidation
#13
Bruno Leandro Pereira, Carlos Maurício Lepienski, Irineu Mazzaro, Neide Kazue Kuromoto
Plasma electrolytic oxidation (PEO) of niobium plates were done electrochemically in two steps with electrolytes containing phosphorous and calcium being observed the formation of crystalline apatite. All samples were submitted to a first step of PEO using an electrolyte containing phosphate ions. The second oxidization step was made using three different electrolytes. Some samples were oxidized by PEO in electrolyte containing calcium, while in other samples it was used two mixtures of phosphoric acid and calcium acetate monohydrate solutions...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28523619/effect-of-calcium-bentonite-on-zn-and-cu-mobility-and-their-accumulation-in-vegetable-growth-in-soil-amended-with-compost-during-consecutive-planting
#14
Quan Wang, Mukesh Kumar Awasthi, Xiuna Ren, Junchao Zhao, Ronghua Li, Feng Shen, Zengqiang Zhang
In this study, greenhouse pot experiment was carried out to investigate the Cu and Zn mobility and their accumulations in pakchoi (Brassica chinensis L.) and Chinese cabbage (Brassica rapachinensis L.) growth in Ca-bentonite-pig manure co-compost (CBC)-soil system during three consecutive planting. Five composts (0, 2.5, 5, 7.5, and 10% Ca-bentonite-pig manure co-composts) amended soil with 5% (w/w) application rate and compared to control without any additive. The results showed that the addition of CBC increased the biomass and chlorophyll content of pakchoi, and the maximum overall yield was found in 7...
May 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28511358/the-degree-of-phosphorus-saturation-of-agricultural-soils-in-germany-current-and-future-risk-of-diffuse-p-loss-and-implications-for-soil-p-management-in-europe
#15
P Fischer, R Pöthig, M Venohr
Decades of intensive agricultural production with excessive application of P fertilizer have resulted in the accumulation of P in soils, threatening water bodies in most industrialized countries with eutrophication. In our study, we elucidated the risk of P loss of German agricultural soils by transforming provided monitoring data of plant-available P determined by the calcium-acetate-lactate (PCAL) and double-lactate method (PDL) into the degree of phosphorus saturation (DPS). As water-soluble phosphorus (WSP) is correlated to DPS, we derived a pedotransfer function (PTF) between PCAL and WSP for different soil types...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28511041/biofilm-formation-and-granule-properties-in-anaerobic-digestion-at-high-salinity
#16
M C Gagliano, S B Ismail, A J M Stams, C M Plugge, H Temmink, J B Van Lier
For the anaerobic biological treatment of saline wastewater, Anaerobic Digestion (AD) is currently a possibility, even though elevated salt concentrations can be a major obstacle. Anaerobic consortia and especially methanogenic archaea are very sensitive to fluctuations in salinity. When working with Upflow Sludge Blanket Reactor (UASB) technology, in which the microorganisms are aggregated and retained in the system as a granular biofilm, high sodium concentration negatively affects aggregation and consequently process performances...
May 10, 2017: Water Research
https://www.readbyqxmd.com/read/28493444/impact-of-hyperlipidaemia-on-intermediary-metabolism-faecal-microbial-metabolites-and-urinary-characteristics-of-lipoprotein-lipase-deficient-vs-normal-cats
#17
N Paßlack, J Zentek, J A Larsen, J L Westropp, A J Fascetti
Findings in humans and rats indicate that hyperlipidaemia may be associated with enhanced endogenous oxalate (Ox) synthesis, which may be relevant for calcium oxalate (CaOx) urolith formation. Moreover, changes in lipid metabolism are proposed to negatively affect gut microbiota. This study aimed to investigate those potential interactions in hyperlipidaemic cats. Therefore, 10 normal control cats and seven lipoprotein lipase (LPL)-deficient cats were fed a low-fat diet for seven weeks. During the last week of the study, cats were housed in metabolic cages to collect urine and faeces...
May 11, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28492868/efficacy-of-flecainide-in-the-treatment-of-catecholaminergic-polymorphic-ventricular-tachycardia-a-randomized-clinical-trial
#18
Prince J Kannankeril, Jeremy P Moore, Marina Cerrone, Silvia G Priori, Naomi J Kertesz, Pamela S Ro, Anjan S Batra, Elizabeth S Kaufman, David L Fairbrother, Elizabeth V Saarel, Susan P Etheridge, Ronald J Kanter, Michael P Carboni, Matthew V Dzurik, Darlene Fountain, Heidi Chen, E Wesley Ely, Dan M Roden, Bjorn C Knollmann
Importance: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially lethal genetic arrhythmia syndrome characterized by polymorphic ventricular tachycardia with physical or emotional stress, for which current therapy with β-blockers is incompletely effective. Flecainide acetate directly suppresses sarcoplasmic reticulum calcium release-the cellular mechanism responsible for triggering ventricular arrhythmias in CPVT-but has never been assessed prospectively. Objective: To determine whether flecainide dosed to therapeutic levels and added to β-blocker therapy is superior to β-blocker therapy alone for the prevention of exercise-induced arrhythmias in CPVT...
May 10, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28482488/direct-bioactive-ceramics-coating-via-reactive-growing-integration-layer-method-on-%C3%AE-ti-alloy
#19
Chi-Huang Huang, Rong-Sheng Chen, Masahiro Yoshimura
This paper demonstrates Ca-P-rich bio-ceramic and hydroxyapatite (HA) coatings formed directly from the solution of calcium acetate (CA) and sodium dihydrogen phosphate (SDP) on α-Ti-alloy substrates by Growing Integration Layer (GIL) technology under DC power supply. The composition of the α-Ti-alloy was Ti7Cu5Sn. The GIL coated films formed in 30min time with different voltages applied had porous and rough ceramic surfaces. They consisted mostly of various oxides like rutile, anatase, and calcium phosphates (including hydroxyapatite) that reduce corrosion rate and increase biocompatibility...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28480489/effect-of-microorganisms-on-reducing-cadmium-uptake-and-toxicity-in-rice-oryza-sativa-l
#20
Chairat Treesubsuntorn, Prapai Dhurakit, Gholamreza Khaksar, Paitip Thiravetyan
This study analyzed the application of three microorganism inoculums, including Bacillus subtilis, Bacillus cereus, and commercial effective microorganism (EM) solution in order to determine cadmium (Cd) reduction in rice (Oryza sativa L.) and rice growth promotion. Rice was grown in Cd-contaminated soil (120 mg/kg) and selected microorganisms were inoculated. Cd concentration and rice weight were measured at 45 and 120 days of the experiment. The result showed that B. subtilis inoculation into rice can highly reduce Cd accumulation in every part of rice roots and shoots (45 days), and grains (120 days)...
May 8, 2017: Environmental Science and Pollution Research International
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