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https://www.readbyqxmd.com/read/28315885/advancement-in-texture-in-early-complementary-feeding-and-the-relevance-to-developmental-outcomes
#1
Jordan R Green, Meg Simione, Benjamin Le Révérend, Erin M Wilson, Brian Richburg, Marc Alder, Mirna Del Valle, Chrystel Loret
A child's transition to independent eating is a protracted process that progresses over the course of many years. Although major health agencies, such as the World Health Organization, now offer clear guidance when to begin introducing solids, advice about how to safely transition to progressively challenging foods is varied and comes from a staggering number of sources. The resulting conflicting views have promoted parental confusion and anxiety about what foods are appropriate and when to advance to new textures...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/28304000/outcome-based-approach-to-medical-education-towards-academic-programmes-accreditation-a-review-article
#2
Abdelmarouf H Mohieldein
The rapid change worldwide, as a consequence of advances in science and technology, necessitates the graduation of well-qualified graduates who have the appropriate knowledge and skills to fulfill specific work requirements. Hence, redesigning academic models by focusing on educational outcomes became the target and priority for universities around the world. In this systematic review we collected and retrieved literature using a selection of electronic databases. The objectives of this report is to: 1) provide an overview of the evolution of outcome-based education (OBE), (2) illustrate the philosophy and principle of OBE, (3) list the OBE advantages and benefits, (4) describe the assessment strategies used in OBE, and (5) discuss the role of teachers and students as key elements...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28302564/tackling-maladaptive-memories-through-reconsolidation-from-neural-to-clinical-science
#3
James W B Elsey, Merel Kindt
Behavioral neuroscience has greatly informed how we understand the formation, persistence, and plasticity of memory. Research has demonstrated that memory reactivation can induce a labile period, during which previously consolidated memories are sensitive to change, and in need of restabilization. This process is known as reconsolidation. Such findings have advanced not only our basic understanding of memory processes, but also hint at the prospect of harnessing these insights for the development of a new generation of treatments for disorders of emotional memory...
March 13, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28301706/facts-values-and-journalism
#4
Susan Gilbert
At a time of fake news, hacks, leaks, and unverified reports, many people are unsure whom to believe. How can we communicate in ways that make individuals question their assumptions and learn? My colleagues at The Hastings Center and many journalists and scientists are grappling with this question and have, independently, reached the same first step: recognize that facts can't be fully understood without probing their connection to values. "Explaining the basics is important, of course, but we also need to diversify our approach to the coverage of science-particularly as it intersects with the matrix of cultural, religious, social, and political values of our readers," said an article in Undark, an online magazine of science journalism...
March 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28298494/student-perceptions-of-online-radiologic-science-courses
#5
Erika Papillion, Laura Aaron
PURPOSE: To evaluate student perceptions of the effectiveness of online radiologic science courses by examining various learning activities and course characteristics experienced in the online learning environment. METHODS: A researcher-designed electronic survey was used to obtain results from students enrolled in the clinical portion of a radiologic science program that offers online courses. The survey consisted of elements associated with demographics, experience, and perceptions related to online radiologic science courses...
March 2017: Radiologic Technology
https://www.readbyqxmd.com/read/28295833/can-we-predict-subject-specific-dynamic-cortical-thickness-maps-during-infancy-from-birth
#6
Yu Meng, Gang Li, Islem Rekik, Han Zhang, Yaozong Gao, Weili Lin, Dinggang Shen
Understanding the early dynamic development of the human cerebral cortex remains a challenging problem. Cortical thickness, as one of the most important morphological attributes of the cerebral cortex, is a sensitive indicator for both normal neurodevelopment and neuropsychiatric disorders, but its early postnatal development remains largely unexplored. In this study, we investigate a key question in neurodevelopmental science: can we predict the future dynamic development of cortical thickness map in an individual infant based on its available MRI data at birth? If this is possible, we might be able to better model and understand the early brain development and also early detect abnormal brain development during infancy...
March 15, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28295204/encouraging-maternal-guidance-of-preschoolers-spatial-thinking-during-block-play
#7
Giulia A Borriello, Lynn S Liben
Spatial thinking, an important component of cognition, supports academic achievement and daily activities (e.g., learning science and math; using maps). Better spatial skills are correlated with more spatial play and more parental attention to spatial concepts. Tested here was whether informing mothers about spatial thinking and ways to encourage it would increase the spatial guidance they provide to their preschool children (N = 41; M = 5.23 years) during dyadic block play. Mothers given such instructions indeed produced more spatial language and spatial guidance than mothers asked to play as usual...
March 13, 2017: Child Development
https://www.readbyqxmd.com/read/28291351/what-can-we-learn-from-a-biomimetic-model-of-nature-s-oxygen-evolving-complex
#8
Satadal Paul, Nicholas Cox, Dimitrios A Pantazis
A recently reported synthetic complex with a Mn4CaO4 core represents a remarkable structural mimic of the Mn4CaO5 cluster in the oxygen-evolving complex (OEC) of photosystem II (Zhang et al., Science 2015, 348, 690). Oxidized samples of the complex show electron paramagnetic resonance (EPR) signals at g ≈ 4.9 and 2, similar to those associated with the OEC in its S2 state (g ≈ 4.1 from an S = (5)/2 form and g ≈ 2 from an S = (1)/2 form), suggesting similarities in the electronic as well as geometric structure...
March 14, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28291277/diagnostiska-fel-och-misstag-%C3%A3-r-vanliga-och-sv%C3%A3-ra-att-m%C3%A3-ta
#9
Anders von Heijne
Diagnostic errors are prevalent and hard to measure Diagnostic errors are prevalent in all aspects of healthcare and a common cause of adverse events. They are often the result of multifactorial events, where there is a complex interplay between cognitive factors, system factors and lack of adequate knowledge. The generic, iterative diagnostic process, with abductive, deductive and inductive components supported by tests and the physical exam, leads to a correct diagnosis for the great majority of patients, but can be derailed by suboptimal thinking, lack of adequate information and external factors such as stress and work overload...
March 13, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28291224/replication-data-collection-highlights-value-in-diversity-of-replication-attempts
#10
K Andrew DeSoto, Martin Schweinsberg
Researchers agree that replicability and reproducibility are key aspects of science. A collection of Data Descriptors published in Scientific Data presents data obtained in the process of attempting to replicate previously published research. These new replication data describe published and unpublished projects. The different papers in this collection highlight the many ways that scientific replications can be conducted, and they reveal the benefits and challenges of crucial replication research. The organizers of this collection encourage scientists to reuse the data contained in the collection for their own work, and also believe that these replication examples can serve as educational resources for students, early-career researchers, and experienced scientists alike who are interested in learning more about the process of replication...
March 14, 2017: Scientific Data
https://www.readbyqxmd.com/read/28287837/scientific-training-in-the-era-of-big-data-a-new-pedagogy-for-graduate-education
#11
Jay Aikat, Thomas M Carsey, Karamarie Fecho, Kevin Jeffay, Ashok Krishnamurthy, Peter J Mucha, Arcot Rajasekar, Stanley C Ahalt
The era of "big data" has radically altered the way scientific research is conducted and new knowledge is discovered. Indeed, the scientific method is rapidly being complemented and even replaced in some fields by data-driven approaches to knowledge discovery. This paradigm shift is sometimes referred to as the "fourth paradigm" of data-intensive and data-enabled scientific discovery. Interdisciplinary research with a hard emphasis on translational outcomes is becoming the norm in all large-scale scientific endeavors...
March 13, 2017: Big Data
https://www.readbyqxmd.com/read/28287586/introducing-clicker-training-as-a-cognitive-enrichment-for-laboratory-mice
#12
Charlotte Leidinger, Felix Herrmann, Christa Thöne-Reineke, Nadine Baumgart, Jan Baumgart
Establishing new refinement strategies in laboratory animal science is a central goal in fulfilling the requirements of Directive 2010/63/EU. Previous research determined a profound impact of gentle handling protocols on the well-being of laboratory mice. By introducing clicker training to the keeping of mice, not only do we promote the amicable treatment of mice, but we also enable them to experience cognitive enrichment. Clicker training is a form of positive reinforcement training using a conditioned secondary reinforcer, the "click" sound of a clicker, which serves as a time bridge between the strengthened behavior and an upcoming reward...
March 6, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28286474/parameters-and-measures-in-assessment-of-motor-learning-in-neurorehabilitation-a-systematic-review-of-the-literature
#13
REVIEW
Nataliya Shishov, Itshak Melzer, Simona Bar-Haim
Upper limb function, essential for daily life, is often impaired in individuals after stroke and cerebral palsy (CP). For an improved upper limb function, learning should occur, and therefore training with motor learning principles is included in many rehabilitation interventions. Despite accurate measurement being an important aspect for examination and optimization of treatment outcomes, there are no standard algorithms for outcome measures selection. Moreover, the ability of the chosen measures to identify learning is not well established...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28282591/a-novel-computer-aided-diagnosis-system-for-breast-mri-based-on-feature-selection-and-ensemble-learning
#14
Wei Lu, Zhe Li, Jinghui Chu
Breast cancer is a common cancer among women. With the development of modern medical science and information technology, medical imaging techniques have an increasingly important role in the early detection and diagnosis of breast cancer. In this paper, we propose an automated computer-aided diagnosis (CADx) framework for magnetic resonance imaging (MRI). The scheme consists of an ensemble of several machine learning-based techniques, including ensemble under-sampling (EUS) for imbalanced data processing, the Relief algorithm for feature selection, the subspace method for providing data diversity, and Adaboost for improving the performance of base classifiers...
March 6, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28282257/human-microbiome-and-learning-healthcare-systems-integrating-research-and-precision-medicine-for-inflammatory-bowel-disease
#15
Kim H Chuong, David R Mack, Alain Stintzi, Kieran C O'Doherty
Healthcare institutions face widespread challenges of delivering high-quality and cost-effective care, while keeping up with rapid advances in biomedical knowledge and technologies. Moreover, there is increased emphasis on developing personalized or precision medicine targeted to individuals or groups of patients who share a certain biomarker signature. Learning healthcare systems (LHS) have been proposed for integration of research and clinical practice to fill major knowledge gaps, improve care, reduce healthcare costs, and provide precision care...
March 10, 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28282171/quantum-machine-learning-over-infinite-dimensions
#16
Hoi-Kwan Lau, Raphael Pooser, George Siopsis, Christian Weedbrook
Machine learning is a fascinating and exciting field within computer science. Recently, this excitement has been transferred to the quantum information realm. Currently, all proposals for the quantum version of machine learning utilize the finite-dimensional substrate of discrete variables. Here we generalize quantum machine learning to the more complex, but still remarkably practical, infinite-dimensional systems. We present the critical subroutines of quantum machine learning algorithms for an all-photonic continuous-variable quantum computer that can lead to exponential speedups in situations where classical algorithms scale polynomially...
February 24, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28282030/platelet-rich-plasma-for-regeneration-of-neural-feedback-pathways-around-dental-implants-a-concise-review-and-outlook-on-future-possibilities
#17
REVIEW
Yan Huang, Michael M Bornstein, Ivo Lambrichts, Hai-Yang Yu, Constantinus Politis, Reinhilde Jacobs
Along with the development of new materials, advanced medical imaging and surgical techniques, osseointegrated dental implants are considered a successful and constantly evolving treatment modality for the replacement of missing teeth in patients with complete or partial edentulism. The importance of restoring the peripheral neural feedback pathway and thus repairing the lack of periodontal mechanoreceptors after tooth extraction has been highlighted in the literature. Nevertheless, regenerating the nerve fibers and reconstructing the neural feedback pathways around osseointegrated implants remain a challenge...
March 10, 2017: International Journal of Oral Science
https://www.readbyqxmd.com/read/28281832/outcomes-of-introducing-early-learners-to-interprofessional-competencies-in-a-classroom-setting
#18
Kelly S Lockeman, Sharon K Lanning, Alan W Dow, Joseph A Zorek, Deborah DiazGranados, Carole K Ivey, Shawne Soper
PROBLEM: Although interprofessional practice is important for improving healthcare delivery, there is little evidence describing interprofessional education (IPE) outcomes beyond changes in attitudes and knowledge of prelicensure learners. More rigorous evaluation of early IPE is needed to determine its impact on teaching interprofessional collaborative practice and providing a solid foundation for applying collaborative skills in the clinical environment. INTERVENTION: First-year students (N = 679) in 7 health professions programs participated in a 4-session series focusing on professional roles and responsibilities, teams and teamwork, and the healthcare system...
March 10, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28281158/mentoring-for-responsible-research-the-creation-of-a-curriculum-for-faculty-to-teach-rcr-in-the-research-environment
#19
Dena K Plemmons, Michael W Kalichman
Despite more than 25 years of a requirement for training in the responsible conduct of research (RCR), there is still little consensus about what such training should include, how it should be delivered, nor what constitutes "effectiveness" of such training. This lack of consensus on content, approaches and outcomes is evident in recent data showing high variability in the development and implementation of RCR instruction across universities and programs. If we accept that one of the primary aims of instruction in RCR/research ethics is "to foster a community of social responsibility" (Antes et al...
March 9, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28279182/the-use-of-mesenchymal-stem-cells-for-cartilage-repair-and-regeneration-a-systematic-review
#20
REVIEW
Andy Goldberg, Katrina Mitchell, Julian Soans, Louise Kim, Razi Zaidi
BACKGROUND: The management of articular cartilage defects presents many clinical challenges due to its avascular, aneural and alymphatic nature. Bone marrow stimulation techniques, such as microfracture, are the most frequently used method in clinical practice however the resulting mixed fibrocartilage tissue which is inferior to native hyaline cartilage. Other methods have shown promise but are far from perfect. There is an unmet need and growing interest in regenerative medicine and tissue engineering to improve the outcome for patients requiring cartilage repair...
March 9, 2017: Journal of Orthopaedic Surgery and Research
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