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https://www.readbyqxmd.com/read/29345752/oxidative-mechanochemistry-for-direct-room-temperature-solvent-free-conversion-of-palladium-and-gold-metals-into-soluble-salts-and-coordination-complexes
#1
Jean-Louis Do, Davin Tan, Tomislav Friscic
Noble metals are valued critical elements whose chemical activation or recycling is challenging, traditionally requiring high temperatures, strong acids or bases, or aggressive complexation agents. Using elementary palladium and gold, we demonstrate mechanochemistry for noble metal activation and recycling via mild, clean, solvent-free and room-temperature chemistry, leading to direct, efficient, one-pot conversion of the metals, including spent catalysts, to simple water-soluble salts, or to metal-organic catalysts...
January 18, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29336853/updated-guidelines-on-infection-prevention-in-pediatric-ambulatory-settings
#2
Deborah L McBride
The American Academy of Pediatrics (AAP) recently released updated guidelines on infection control and prevention in pediatric outpatient settings. Key recommendations include mandatory influenza vaccination for all healthcare workers offered free to all staff, expanded guidance on infection control practices for children with cystic fibrosis, guidance on additional prevention procedures during community outbreaks of infectious diseases and recommendations on improving communication between healthcare facilities when referring potentially contagious patients...
January 11, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29331170/implementation-lessons-learned-from-the-benefits-of-enhanced-terminal-room-betr-disinfection-study-process-and-perceptions-of-enhanced-disinfection-with-ultraviolet-disinfection-devices
#3
Deverick J Anderson, Lauren P Knelson, Rebekah W Moehring, Sarah S Lewis, David J Weber, Luke F Chen, Patricia F Triplett, Michael Blocker, R Marty Cooney, J Conrad Schwab, Yuliya Lokhnygina, William A Rutala, Daniel J Sexton
OBJECTIVE To summarize and discuss logistic and administrative challenges we encountered during the Benefits of Enhanced Terminal Room (BETR) Disinfection Study and lessons learned that are pertinent to future utilization of ultraviolet (UV) disinfection devices in other hospitals DESIGN Multicenter cluster randomized trial SETTING AND PARTICIPANTS Nine hospitals in the southeastern United States METHODS All participating hospitals developed systems to implement 4 different strategies for terminal room disinfection...
January 14, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29328742/pragmatic-recycling-of-paper-and-cardboard-in-the-operating-theatre-an-audit
#4
Douglas Ra McKendrick, Lorraine J Snedden, Rozel Bunch, Hazel McGregor
Despite recent legislation introduced in Scotland and motivated recycling at home, very little recycling exists within theatre environments. This study audited the introduction of recycling of paper and cardboard. All waste within a single operating theatre was collected by a dedicated team for 20 surgical cases. The collection of clean paper and cardboard packaging was limited to the theatre preparation room (TPR) and anaesthetic room (AR). No waste segregation was attempted within the operating theatre itself...
March 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29325198/-hygienic-inspections-of-ventilation-systems-under-resting-conditions-according-to-din-1946-4-1999-03-a-retrospective-assessment
#5
Lena Friedrich, Irina Boeckelmann
BACKGROUND: Hygienic and microbiologically sterile air quality is essential for successful guideline-based work in operating theatres. To ensure clean air and to reduce contamination during surgery, ventilation systems are indispensable. Ventilation systems should be especially designed to keep the number of particles and germs under statutory limits. Therefore, they must be operated to recognised standards of good practice and be periodically inspected and maintained. The objective of this study was to prove, through the analysis of observation outside surgery time (rest condition), the effects of ventilation systems on air quality in a medical facility...
January 11, 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29306489/efficacy-of-manual-cleaning-and-an-ultraviolet-c-room-decontamination-device-in-reducing-health-care-associated-pathogens-on-hospital-floors
#6
Aishat Mustapha, Heba Alhmidi, Jennifer L Cadnum, Annette L Jencson, Curtis J Donskey
Recent studies suggest that floors may be an underappreciated source for transmission of health care-associated pathogens. However, there are limited data on the effectiveness of current cleaning and disinfection methods in reducing floor contamination. We demonstrated that manual postdischarge cleaning by environmental services personnel significantly reduced floor contamination, and an automated ultraviolet C room disinfection device was effective as an adjunct to manual cleaning.
January 4, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29305694/pervasiveness-of-uvc254-resistant-geobacillus-strains-in-extreme-environments
#7
Courtney Carlson, Nitin K Singh, Mohit Bibra, Rajesh K Sani, Kasthuri Venkateswaran
We have characterized a broad collection of extremophilic bacterial isolates from a deep subsurface mine, compost dumping sites, and several hot spring ecosystems. Spore-forming strains isolated from these environments comprised both obligate thermophiles/thermotolerant species (growing at > 55 °C; 240 strains) and mesophiles (growing at 15 to 40 °C; 12 strains). An overwhelming abundance of Geobacillus (81.3%) and Bacillus (18.3%) species was observed among the tested isolates. 16S rRNA sequence analysis documented the presence of 24 species among these isolates, but the 16S rRNA gene was shown to possess insufficient resolution to reliably discern Geobacillus phylogeny...
January 5, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29302800/analysis-of-fungi-in-aerosols-dispersed-by-high-speed-pens-in-dental-clinics-from-teresina-piaui-brazil
#8
Aline Maria Alves Vilarinho Oliveira, Rômulo Maia de Alencar, Jhonatas Cley Santos Porto, Isla Rita Brito Fontenele Ramos, Iraci Salmito Noleto, Tanit Clementino Santos, Mitra Mobin
This quantitative and qualitative study aimed to evaluate the level of fungal contamination in aerosols dispersed by high rotation pens in dental clinics from Teresina, Piaui, Brazil. The data were collected during the attendance at two dental clinics. Petri dishes containing Sabouraud agar with chloramphenicol were opened for 15 min in the following places: in front of the chair, on the partitions to the right and left of the chair, and in the neighboring workbench. The plates were incubated at room temperature to allow the fungal growth and subsequent species identification...
January 4, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29290480/cleaning-the-air-with-ultraviolet-germicidal-irradiation-lessened-contact-infections-in-a-long-term-acute-care-hospital
#9
Tina Ethington, Sherry Newsome, Jerri Waugh, Linda D Lee
BACKGROUND: This study was designed to determine whether removing bacteria from the air with ultraviolet germicidal irradiation (UV-C) at the room level would reduce infection rates. METHODS: We reviewed infection data for 12 months before and after UV-C installation in the special care unit (SCU) of a long-term acute care hospital. All patients admitted to the SCU during the study time frame were included. Microbiologic impactor air sampling was completed in August 2015...
December 29, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29287970/closed-system-manufacturing-of-cd19-and-dual-targeted-cd20-19-chimeric-antigen-receptor-t-cells-using-the-clinimacs-prodigy-device-at-an-academic-medical-center
#10
Fenlu Zhu, Nirav Shah, Huiqing Xu, Dina Schneider, Rimas Orentas, Boro Dropulic, Parameswaran Hari, Carolyn A Keever-Taylor
BACKGROUND AIMS: Multiple steps are required to produce chimeric antigen receptor (CAR)-T cells, involving subset enrichment or depletion, activation, gene transduction and expansion. Open processing steps that increase risk of contamination and production failure are required. This complex process requires skilled personnel and costly clean-room facilities and infrastructure. Simplified, reproducible CAR-T-cell manufacturing with reduced labor intensity within a closed-system is highly desirable for increased availability for patients...
December 26, 2017: Cytotherapy
https://www.readbyqxmd.com/read/29285204/surface-structure-of-tio2-rutile-011-exposed-to-liquid-water
#11
Jan Balajka, Ulrich Aschauer, Stijn F L Mertens, Annabella Selloni, Michael Schmid, Ulrike Diebold
The rutile TiO2(011) surface exhibits a (2 × 1) reconstruction when prepared by standard techniques in ultrahigh vacuum (UHV). Here we report that a restructuring occurs upon exposing the surface to liquid water at room temperature. The experiment was performed in a dedicated UHV system, equipped for direct and clean transfer of samples between UHV and liquid environment. After exposure to liquid water, an overlayer with a (2 × 1) symmetry was observed containing two dissociated water molecules per unit cell...
November 30, 2017: Journal of Physical Chemistry. C, Nanomaterials and Interfaces
https://www.readbyqxmd.com/read/29284952/an-evaluation-of-the-effect-of-various-gloves-on-polymerization-inhibition-of-elastomeric-impression-materials-an-in-vitro-study
#12
Vinuta Hiremath, G Vinayakumar, Mallikarjuna Ragher, Sounyala Rayannavar, Mahantesh Bembalagi, B L Ashwini
Background: Latex protective barriers such as gloves and rubber dam material have been used widely in restorative procedures for crown and bridge. However, the chemical used during latex glove fabrication is thought to inhibit the polymerization of elastomeric impression materials used for impression making which has a detrimental effect on the dimensional accuracy and surface definition of resultant casts used for restorative procedures. The objectives of the study were to examine the surface of different elastomeric impressions on contact with various gloves...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284358/storage-and-transport-of-reconstituted-omacetaxine-mepesuccinate-considerations-for-home-administration
#13
Alpa Parikh, Jennifer van de Rijn, Chris Melville, Marazban Sarkari, Sylvie Peltier, Robert McKean
Purpose Omacetaxine mepesuccinate ("omacetaxine") is approved by the US Food and Drug Administration for the treatment of adult patients with chronic- or accelerated-phase chronic myeloid leukemia with resistance and/or intolerance to two or more tyrosine kinase inhibitors. In May 2014, the US Food and Drug Administration approved revisions to the packaging information that included directions for home administration of reconstituted omacetaxine by patients or caregivers using syringes filled at a healthcare facility...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29283921/a-simulation-study-to-evaluate-improvements-in-anesthesia-work-environment-contamination-after-implementation-of-an-infection-prevention-bundle
#14
Grete H Porteous, Helen A Bean, Crystal M Woodward, Ryan P Beecher, Jennifer R Bernstein, Sarah Wilkerson, Ian Porteous, Robert L Hsiung
BACKGROUND: Microbiological contamination of the anesthesia work environment (AWE) is a potential source of health care-associated infections. Medication syringes, stopcocks, and many other areas are routinely contaminated during anesthetic care, and adherence to hand hygiene recommendations is poor. Using a simulation model, we investigated whether AWE contamination could be reduced by implementing an intervention bundle focused on infection prevention. METHODS: Twenty-five anesthesia providers were enrolled in this nonrandomized simulation scenario crossover design study...
December 26, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29283367/surveillance-of-environmental-and-procedural-measures-of-infection-control-in-the-operating-theatre-setting
#15
Laura Dallolio, Alessandra Raggi, Tiziana Sanna, Magda Mazzetti, Alessandra Orsi, Angela Zanni, Patrizia Farruggia, Erica Leoni
The microbiological contamination of operating theatres and the lack of adherence to best practices by surgical staff represent some of the factors affecting Surgical Site Infections (SSIs). The aim of the present study was to assess the microbiological quality of operating settings and the staff compliance to the SSI evidence-based control measures. Ten operating rooms were examined for microbiological contamination of air and surfaces, after cleaning procedures, in "at rest" conditions. Furthermore, 10 surgical operations were monitored to assess staff compliance to the recommended practices...
December 28, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29281998/interaction-of-healthcare-worker-hands-and-portable-medical-equipment-a-sequence-analysis-to-show-potential-transmission-opportunities
#16
Chetan Jinadatha, Frank C Villamaria, John D Coppin, Charles R Dale, Marjory D Williams, Ryan Whitworth, Mark Stibich
BACKGROUND: While research has demonstrated the importance of a clean health care environment, there is a lack of research on the role portable medical equipment (PME) play in the transmission cycle of healthcare-acquired infections (HAIs). This study investigated the patterns and sequence of contact events among health care workers, patients, surfaces, and medical equipment in a hospital environment. METHODS: Research staff observed patient care events over six different 24 h periods on six different hospital units...
December 28, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29261663/comparative-study-of-impaction-and-sedimentation-in-an-aerosol-chamber-using-defined-fungal-spore-and-bacterial-concentrations
#17
Doris Haas, Herbert Galler, Carola Fritz, Christina Hasler, Juliana Habib, Franz F Reinthaler
Biocontamination control is a very significant part of the manufacturing process of sterile drugs. Sterility is frequently monitored by active or passive air sampling measurements, but there are no specific rules as to how this is to be done. This study tested air sampling methods of active impaction and passive sedimentation under standardized conditions. Aspergillus niger (A. niger) and Staphylococcus aureus (S. aureus) were selected in this experiment to examine parallels, correlations and differences between the two methods...
2017: PloS One
https://www.readbyqxmd.com/read/29249145/carboxylic-acid-group-induced-oxygen-vacancy-migration-on-anatase-101-surface
#18
Yadong Li, Yi Gao
Dye-sensitized solar cells have aroused intensive interest for the replacement of conventional crystalline silicon solar cells. Through carboxylic acid groups, the dyes attach to the TiO2 anatase (101) surface, on which the subsurface oxygen vacancies are predominant. The performance of dye-sensitized solar cells can be affected by the presence and positions of oxygen vacancies. By applying density functional theory calculations, we found the adsorption of carboxylic acid group decorated dye molecule reverses the relative stability between the surface and subsurface oxygen vacancy on anatase (101) surface, which facilitates the migration of oxygen vacancy from subsurface to surface by overcoming an energy barrier of less than 0...
December 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29246649/utility-of-routine-evaluation-of-sterility-of-cellular-therapy-products-with-or-without-extensive-manipulation-best-practices-and-clinical-significance
#19
Josee Golay, Olga Pedrini, Chiara Capelli, Elisa Gotti, Gianmaria Borleri, Mara Magri, Francesca Vailati, Marco Passera, Claudio Farina, Alessandro Rambaldi, Martino Introna
BACKGROUND: We analyzed the results of routine sterility testing performed in our center over the last 10 years, in the context both hematopoietic stem cell transplantation (HSCT) and Advanced Therapeutic Medicinal Products (ATMPs). METHODS: For sterility tests 14-day cultures were performed in culture media detecting aerobic and anaerobic microorganisms. RESULTS: In this study, 22/1643 (1.3%) of apheretic products for autologous or allogeneic HSCT were contaminated, whereas 14/73 bone marrow (BM) harvests (17...
December 12, 2017: Cytotherapy
https://www.readbyqxmd.com/read/29229004/environmental-cleaning-of-outpatient-exam-rooms-how-frequent-is-enough
#20
Shela Sridhar, Mary Beth Graham, Sabrina Savage-Taft, John Fangman, L Silvia Munoz-Price
No abstract text is available yet for this article.
December 12, 2017: Infection Control and Hospital Epidemiology
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