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Clean room

Olivia Ellis, Hilary Godwin, Maren David, Dan J Morse, Romney Humphries, Daniel Z Uslan
BACKGROUND: A major limitation to developing evidence-based approaches to infection prevention is the paucity of real-time, quantitative methods for monitoring the cleanliness of environmental surfaces in clinical settings. One solution that has been proposed is adenosine triphosphate (ATP) bioluminescence assays, but this method does not provide information about the source of the ATP. MATERIALS/METHODS: To address this gap, we conducted a study in which ATP bioluminescence was coupled with traditional RODAC sampling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry to assess which organisms were viable and present...
May 17, 2018: American Journal of Infection Control
Marek Wiergowski, Ireneusz Sołtyszewski, Jacek Sein Anand, Michał Kaliszan, Jolanta Anita Wilmanowska, Zbigniew Jankowski, Marcin Łukasik
The purpose of this study was a toxicological interpretation of exposure to chlorine with unusual course. Medical, clinical and court records, as well as reviews of the literature, served as the basis for this interpretation. The first case of poisoning concerns a 52-year-old man who for a short time (probably several hours), during the industrial cleaning of facilities with sodium hypochlorite, was exposed to chlorine in a presumed high concentration. The man was obese and suffered from hypertension and moderate atherosclerosis, and therefore could be more susceptible to the toxic effects of chlorine...
May 8, 2018: Journal of Forensic and Legal Medicine
Xiaoyang Pan, Chao Li, Jing Zheng, Shijing Liang, Rong Huang, Zhiguo Yi
Noble metal nanoparticles have attracted considerable attention due to their useful capabilities as heterogeneous catalysts. However, they are usually prepared using various organic stabilizing agents that negatively affect their catalytic activities. Herein, we report a facile, clean, and effective method for synthesizing supported ultrafine noble metal nanoparticles by utilizing the reductive property of a new pyrochlore oxide: Sn1.06 Nb2 O5.59 F0.97 (SnNbOF). Ultrafine Au, Pd, and Pt nanoparticles or clusters are homogeneously distributed on the SnNbOF surface...
May 18, 2018: Inorganic Chemistry
Roselyn Kahindi, Alemu Regassa, John Htoo, Martin Nyachoti
Two 14-day experiments, each with 90 (Duroc × [Yorkshire × Landrace]; 7.3 ± 0.6 kg) piglets, were conducted to determine the optimum sulfur amino acid (SAA) to lysine (Lys) ratio (SAA:Lys) for piglets when reared under clean or unclean sanitary conditions using performance and non-performance response criteria. Piglets were randomly assigned to the following dietary treatments. The basal diet contained 1.18% standardized ileal digestible (SID) Lys, and the SAA:Lys was 52%. In diets 2 to 5, the basal diet was supplemented with 4 graded levels of dl-Met to make SAA:Lys of 56%, 60%, 64% and 68%...
December 2017: Animal nutrition
Shi-Qi An, Gabriele Berg
This infographic describes the key regulated traits of Stenotrophomonas maltophilia, important for beneficial plant interactions, and also its increasing incidence as a nosocomial and community-acquired infection. Stenotrophomonas maltophilia is a cosmopolitan and ubiquitous bacterium found in a range of environmental habitats, including extreme ones, although in nature it is mainly associated with plants. S. maltophilia fulfils important ecosystem functions in the sulfur and nitrogen cycles, in degradation of complex compounds and pollutants, and in promoti on of plant growth and health...
May 10, 2018: Trends in Microbiology
A M G A Laheij, J J de Soet, C M C Volgenant
The increasing resistance to antibiotics and the aging of the population of patients who visit the dental practice can lead to more frequent infections with (resistant) microorganisms. The prevention of cross contamination by the implementation of effective measures in the area of hygiene and procedures of infection control is therefore important. The furnishing of a dental practice can play an important part in prevention. What are the important issues in furnishing a practice? A distinction is made between 'critical' and 'non-critical' rooms...
May 2018: Nederlands Tijdschrift Voor Tandheelkunde
Muhammad Moniruzzaman, Masahiro Goto
Ionic liquids (ILs), a potentially attractive "green," recyclable alternative to environmentally harmful volatile organic compounds, have been increasingly exploited as solvents and/or cosolvents and/or reagents in a wide range of applications, including pretreatment of lignocellulosic biomass for further processing. The enzymatic delignification of biomass to degrade lignin, a complex aromatic polymer, has received much attention as an environmentally friendly process for clean separation of biopolymers including cellulose and lignin...
May 10, 2018: Advances in Biochemical Engineering/biotechnology
Guangyu Cao, Madeleine C A Storås, Amar Aganovic, Liv-Inger Stenstad, Jan Gunnar Skogås
BACKGROUND: Airflow distribution in the operating room plays an important role in ensuring a clean operating microenvironment and preventing surgical site infections (SSIs) caused by airborne contaminations. The objective of this study was to characterize the airflow distribution in proximity to a patient in an orthopedic operating room. METHODS: Experimental measurements were conducted in a real operating room at St. Olav's Hospital, Norway, with a laminar airflow system...
May 4, 2018: American Journal of Infection Control
Thalita Dallapícula Ramos, Miguel de la Guardia, Agustín Pastor, Francesc A Esteve-Turrillas
A calibration chamber has been designed and employed for the simple and easy determination of uptake sampling rate (RS ) of volatile organic compounds (VOCs) from air using passive samplers. A flow of clean air was continuously spiked, at a constant VOC concentration, by the microinjection of a standard solution by means of a T-type tube. The developed system allowed the complete evaporation at room temperature of the standard solution in acetone and the air concentration of VOCs was easily controlled by the regulation of the clean air flow, the standard solution concentration and its flow...
April 1, 2018: Science of the Total Environment
Burkhard Horstkotte, Natalia Lopez de Los Mozos Atochero, Petr Solich
Online coupling of Lab-In-Syringe automated headspace extraction to gas chromatography has been studied. The developed methodology was successfully applied to surface water analysis using benzene, toluene, ethylbenzene, and xylenes as model analytes. The extraction system consisted of an automatic syringe pump with a 5 mL syringe into which all solutions and air for headspace formation were aspirated. The syringe piston featured a longitudinal channel, which allowed connecting the syringe void directly to a gas chromatograph with flame ionization detector via a transfer capillary...
April 23, 2018: Journal of Chromatography. A
Brian A Rosen, Idan Hod
Electrochemical CO2 reduction provides a clean and viable alternative for mitigating the environmental aspects of global greenhouse gas emissions. To date, the simultaneous goals of CO2 reduction at high selectivity and activity have yet to be achieved. Here, the importance of engineering both sides of the electrode-electrolyte interface as a rational strategy for achieving this milestone is highlighted. An emphasis is placed on researchers contributing to the design of solid electrodes based on metal-organic frameworks (MOFs) and electrolytes based on room-temperature ionic liquids (RTILs)...
April 25, 2018: Advanced Materials
Marc K Kouam, Manjeli Jacouba, Inouss N Nsangou, Alexis Teguia
The recent outbreak of avian influenza in the poultry sector of Cameroon has raised a concern about the level of implementation of biosecurity measures (BM) on poultry farms. Therefore, a study using a questionnaire on 102 randomly selected poultry farms was undertaken. Some measures with high adoption levels (> 90%) included "protection of airing openings of poultry barns by a wire mesh," "no external animal allowed to enter the farm," "respect of all-in all-out principle," "functional footbath," "rodent control," and "feedstuff protection from access to rodents...
April 23, 2018: Tropical Animal Health and Production
Justin L Regner, Matthew J Forestiere, Yolanda Munoz-Maldonado, Richard Frazee, Travis S Isbell, Claire L Isbell, Randall W Smith, Stephen W Abernathy
A negative pressure wound therapy (NPWT) protocol using Hydrofera Blue® bacteriostatic foam wicks and silver-impregnated foam overlay to close midline skin incisions after emergency celiotomy was compared to primary skin closure only and traditional open wound vacuum-assisted closure management as part of a quality improvement initiative. This single-institution retrospective cohort study assessed all consecutive emergency celiotomies from July 2013 to June 2014 excluding clean wounds. Included variables were demographics, wound classification, NPWT days, and surgical site occurrences (SSOs)...
January 2018: Proceedings of the Baylor University Medical Center
Tian Tian, Rongrong Hu, Ben Zhong Tang
The utilization of sulfur is a global concern, considering the abundant and cheap source of sulfur from nature and petroleum industry, its limited consumption and the safety/environmental problems caused during storage. The economic and efficient transformation of sulfur remains to be a great challenge for both academia and industry. Herein, a room temperature conversion from sulfur to functional polythioureas was reported through a catalyst-free multicomponent polymerization of sulfur, aliphatic diamines, and diisocyanides in air with 100% atom economy...
April 23, 2018: Journal of the American Chemical Society
Yuanyuan Cheng, Bei Wu, Xiaofan Ma, Shixiang Lu, Wenguo Xu, Sabine Szunerits, Rabah Boukherroub
Inspired by the lotus effect and water-repellent properties of water striders' legs, superhydrophobic surfaces have been intensively investigated from both fundamental and applied perspectives for daily and industrial applications. Various techniques are available for the fabrication of artificial superoleophilic/superhydrophobic (SS). However, most of these techniques are tedious and often require hazardous or expensive equipment, which hampers their implementation for practical applications. In the present work, we used a versatile and straightforward technique based on polymer drop-casting for the preparation SS materials that can be implemented on any substrate...
April 18, 2018: Journal of Colloid and Interface Science
Gianluca Tenore, Gaspare Palaia, Chiara Ciolfi, Mohamed Mohsen, Andrea Battisti, Umberto Romeo
Introduction: Cervicofacial subcutaneous emphysema is defined as the abnormal introduction of air in the subcutaneous tissues of the head and neck. It is mainly caused by trauma, head and neck surgery, general anesthesia, and coughing or habitual performance of Valsalva manoeuvre. The occurrence of subcutaneous emphysema after dental treatment is rare, and diffusion of gas into the mediastinum is much rarer, especially when the procedure is a nonsurgical treatment. Presented here is a case of subcutaneous emphysema that occurred after sodium hypochlorite irrigation during endodontic treatment, and the description of its etiologies and prevention during nonsurgical endodontic treatment...
September 2017: Annali di Stomatologia
Byeong-Cheol Kang, Jun-Young Jeon, Young Tae Byun, Tae-Jun Ha
In this paper, we demonstrate the highly sensitive carbon nanotube (CNT) sensors for the detection of sub-ppm nitric oxide (NO) gas operating at room temperature. Such achievement can be realized by functionalizing CNT thin films with amine-based polymers through a solution-process technology at low temperature. In addition to high sensitivity, functionalized CNT sensors exhibit high selectivity towards NO gas, which is an effective and practical factor for health-care monitoring nano-electronics. We also investigated the effect of a post-cleaning treatment on the sensing performance of functionalized CNT thin films for sub-ppm NO gas sensors...
September 1, 2018: Journal of Nanoscience and Nanotechnology
Sarah Simmons, Charles Dale, James Holt, Deborah G Passey, Mark Stibich
BACKGROUND: Manual cleaning and disinfection of the operating room (OR) environment may be inadequate due to human error. No-touch technologies, such as pulsed-xenon ultraviolet light (PX-UV), can be used as an adjunct to manual cleaning processes to reduce surface contamination in the OR. This article reports the cumulative results from 23 hospitals across the United States that performed microbiologic validation of PX-UV disinfection after manual cleaning. METHODS: We obtained samples from 732 high-touch surfaces in 136 ORs at 23 hospitals, after manual terminal cleaning, and again after PX-UV disinfection (n = 1464 surface samples)...
April 13, 2018: American Journal of Infection Control
Tarik D Madni, Jonathan B Imran, Audra T Clark, Holly B Cunningham, Luis Taveras, Brett D Arnoldo, Herb A Phelan, Steven E Wolf
Introduction: Previously, we identified that 60% of our facility's total operative time is nonoperative. We performed a review of our operating room to determine where inefficiencies exist in nonoperative time. Methods: Live video of operations performed in a burn operating room from 6/23/17 to 8/16/17 were prospectively reviewed. Preparation (end of induction to procedure start) and turnover (patient out of room to next patient in room) were divided into the following activities: 1) Preparation: remove dressing, position patient, clean patient, drape patient, and 2) Turnover: clean operating room, scrub tray set-up, anesthesia set-up...
April 6, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
John E Zeber, Christopher Pfeiffer, John W Baddley, Jose Cadena-Zuluaga, Eileen M Stock, Laurel A Copeland, Janet Hendricks, Jwan Mohammadi, Marcos I Restrepo, Chetan Jinadatha
BACKGROUND: Inadequate environmental disinfection represents a serious risk for health care-associated infections. Technologic advancements in disinfection practices, including no-touch devices, offer significant promise to improve infection control. We evaluated one such device, portable pulsed xenon ultraviolet (PX-UV) units, on microbial burden during an implementation trial across 4 Veterans Affairs hospitals. METHODS: Environmental samples were collected before and after terminal room cleaning: 2 facilities incorporated PX-UV disinfection into their cleaning protocols and 2 practiced manual disinfection only...
April 11, 2018: American Journal of Infection Control
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