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Ileal pouch

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https://www.readbyqxmd.com/read/27902515/comparison-of-health-related-quality-of-life-and-disability-in-ulcerative-colitis-patients-following-restorative-proctocolectomy-with-ileal-pouch-anal-anastomosis-versus-anti-tumor-necrosis-factor-therapy
#1
Sara van Gennep, Saloomeh Sahami, Christianne J Buskens, Gijs R van den Brink, Cyriel Y Ponsioen, André D'Hoore, Anthony de Buck van Overstraeten, Gert van Assche, Marc Ferrante, Séverine Vermeire, Willem A Bemelman, Geert R A M D'Haens, Mark Löwenberg
BACKGROUND AND AIMS: Health-related quality of life (HRQL) and disability were compared in ulcerative colitis (UC) patients who underwent restorative proctocolectomy versus patients who received treatment with anti-tumor necrosis factor (anti-TNF) agents. PATIENTS AND METHODS: UC patients who underwent restorative proctocolectomy or started anti-TNF treatment between January 2010 and January 2015 were included at two tertiary referral centers. A matched cohort was created using propensity score matching for the covariates disease duration, Montreal classification, age, and sex...
November 29, 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27896653/clinical-characteristics-of-stoma-related-obstruction-after-ileal-pouch-anal-anastomosis-for-ulcerative-colitis
#2
Yoshiki Okita, Toshimitsu Araki, Satoru Kondo, Hiroyuki Fujikawa, Shigeyuki Yoshiyama, Junichiro Hiro, Mikihiro Inoue, Yuji Toiyama, Minako Kobayashi, Masaki Ohi, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
AIMS: We defined small bowel obstruction occurring around the limbs of the ileostomy as stoma-related obstruction (SRO) and investigated the clinical characteristics and predictive factors of SRO. METHODS: From January 2002 to March 2016, 309 consecutive patients who underwent ileal pouch-anal anastomosis (IPAA) for ulcerative colitis were enrolled. Two-stage IPAA with diverting ileostomy was analyzed. We assessed the possible associations between SRO and clinical factors...
November 28, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27885870/transanal-total-mesorectal-excision-for-restorative-coloproctectomy-in-an-obese-high-risk-patient-with-colitis-associated-carcinoma
#3
Laura Isabel Hanke, Fabian Bartsch, Sebastian Försch, Florian Heid, Hauke Lang, Werner Kneist
Transanal total mesorectal excision (TaTME) offers great potential for the treatment of malign and benign diseases. However, laparoscopic-assisted TaTME in ulcerative colitis has not been described in more than a handful of patients. We present a 47-year-old highly comorbid female patient with an ulcerative colitis-associated carcinoma of the ascending colon and steroid-refractory pancolitis. A two-stage restorative coloproctectomy including right-sided complete mesocolic excision was conducted. The second step consisted of a successful nerve-sparing TaTME and a handsewn ileal pouch-anal anastomosis...
November 25, 2016: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/27843448/could-total-colectomy-with-ileorectal-anastomosis-be-an-alternative-to-total-proctocolectomy-with-ileal-pouch-anal-anastomosis-in-selected-ulcerative-colitis-patients
#4
Francesco Tonelli, Carmela Di Martino, Francesco Giudici
Purpose. To evaluate ileorectal anastomosis (IRA) in selected ulcerative colitis patients. Methods. Early and late complications after IRA and IPAA were investigated. Bowel function and quality of life were assessed. Functional and QoL studies were performed as a matched pair analysis, comparing 98 patients who underwent IRA versus 98 patients who underwent IPAA. Results. In IRA group, 2 patients (1.6%) developed anastomotic l dysplasia (HGD) developed in 3 patients dysplasia (HGD) developed in 3 patients eakage, 1 patient (0...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/27833384/fecal-microbiota-in-pouchitis-and-ulcerative-colitis
#5
Kai-Yu Li, Jian-Lin Wang, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu
AIM: To investigate the changes in microbiota in feces of patients with ulcerative colitis (UC) and pouchitis using genomic technology. METHODS: Fecal samples were obtained from UC patients with or without an ileal pouch-anal anastomosis (IPAA) procedure, as well as healthy controls. The touchdown polymerase chain reaction technique was used to amplify the whole V3 region of the 16S rRNA gene, which was transcribed from DNA extracted from fecal samples. Denaturing gradient gel electrophoresis was used to separate the amplicons...
October 28, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27832426/long-term-outcomes-in-indeterminate-colitis-patients-undergoing-ileal-pouch-anal-anastomosis-function-quality-of-life-and-complications
#6
Katharine L Jackson, Luca Stocchi, Leonardo Duraes, Ahmet Rencuzogullari, Ana E Bennett, Feza H Remzi
INTRODUCTION: It is uncertain whether the outcomes of patients with indeterminate colitis (IC) undergoing ileal pouch-anal anastomosis (IPAA) deteriorate over time. The aim of this study was to determine the long-term pouch function, quality of life, complications, and incidence of Crohn's disease after IPAA for patients with IC compared to ulcerative colitis (UC). METHODS: A case matched analysis was performed on patients undergoing IPAA for pathologically confirmed IC or UC, between 1985 and 2014...
November 10, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27831543/a-distinct-colon-derived-breath-metabolome-is-associated-with-inflammatory-bowel-disease-but-not-its-complications
#7
Florian Rieder, Satya Kurada, David Grove, Frank Cikach, Rocio Lopez, Nishaben Patel, Amandeep Singh, Naim Alkhouri, Bo Shen, Aaron Brzezinski, Mark Baker, Claudio Fiocchi, Raed A Dweik
OBJECTIVES: The accuracy of available noninvasive biomarkers for diagnosis, stratification, and prediction of inflammatory bowel disease (IBD) courses is limited. We analyzed volatile organic compounds (VOCs) in the breath of IBD patients and controls for diagnosis and differentiation of IBD as well as their link with disease location, activity, and phenotype. METHODS: A prospective study of diagnostic testing was conducted, recruiting Crohn's disease (CD), ulcerative colitis (UC), other inflammatory gastrointestinal diseases (OGDs), and healthy controls (HCs), as well as subjects with ileal pouch anal anastomosis (IPAA)...
November 10, 2016: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/27822874/spinal-epidural-abscess-a-rare-complication-of-ulcerative-colitis-after-ileal-pouch-anal-anastomosis
#8
Mikio Kawamura, Toshimitsu Araki, Yoshiki Okita, Satoru Kondo, Takashi Ichikawa, Hiroyuki Fujikawa, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
BACKGROUND: Spinal epidural abscess is a rare condition with high morbidity and mortality, for which a delay in diagnosis and treatment can lead to irreversible neurologic deficit or even death. Although patients with spinal epidural abscess have systemic predisposing immunocompromised conditions, spinal intervention, or trauma, this condition has been reported as a result of perforation or fistulization arising from inflammatory bowel disease. We describe herein a rare case of spinal epidural abscess as a complication of ileal pouch anal anastomosis...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27822614/outcome-and-functional-prognosis-of-pelvic-sepsis-after-ileal-pouch-anal-anastomosis-in-patients-with-ulcerative-colitis
#9
Shozo Ide, Toshimitsu Araki, Yoshiki Okita, Mikio Kawamura, Yuji Toiyama, Minako Kobayashi, Masaki Ohi, Koji Tanaka, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
PURPOSE: Restorative proctocolectomy with ileal pouch-anal anastomosis is a surgical procedure for ulcerative colitis, but pouch failure or pelvic sepsis still occurs in some patients. We conducted this study to investigate the cause of pouch failure and evaluate defecatory function after pelvic sepsis. METHODS: A total of 234 patients who underwent restorative proctocolectomy were enrolled. We analyzed the cause of pouch failure, as well as defecatory function and manometric outcomes, with and without the complication of pelvic sepsis...
November 7, 2016: Surgery Today
https://www.readbyqxmd.com/read/27813487/-quality-of-life-after-colectomy-due-to-ulcerative-colitis
#10
Katrin Gudlaugsdottir, Elsa B Valsdottir, Tryggvi B Stefansson
INTRODUCTION: A significant proportion of patients with ulcerative colitis (UC) undergo colectomy. The aim was to assess the quality of life (QOL) of these patients. MATERIAL AND METHODS: All patients with UC who underwent colectomy at The National University Hospital of Iceland or Akureyri Hospital 1995-2009 were included. 106 patients received three questionnaires. SF-36v2 and EORTC are standardised QOL-questionnaires. The third contained functional questions designed by the researchers...
November 2016: Læknablađiđ
https://www.readbyqxmd.com/read/27809887/successful-endoscopic-treatment-of-stapled-j-pouch-ileoanal-canal-anastomotic-hemorrhage-by-argon-plasma-coagulation-a-case-report
#11
Takeshi Nishikawa, Keisuke Hata, Shuntaro Yoshida, Koji Murono, Koji Yasuda, Kensuke Otani, Toshiaki Tanaka, Tomomichi Kiyomatsu, Kazushige Kawai, Hiroaki Nozawa, Soichiro Ishihara, Kazuhiko Koike, Toshiaki Watanabe
BACKGROUND: Continuous lower gastrointestinal hemorrhage is a rare condition, but it often requires proper management. We report a case of a patient with gastrointestinal hemorrhage 18 years after stapled J-pouch ileoanal canal anastomosis who was successfully treated with argon plasma coagulation. CASE PRESENTATION: Our patient was a 54-year-old Japanese man who had developed ulcerative colitis 28 years ago. A J-shaped ileal pouch-anal anastomosis with a double-staple technique was indicated 18 years ago when the patient became refractory to the conventional medication...
November 3, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27807581/pouchitis-associated-with-pelvic-radiation-for-prostate-cancer
#12
Geeta Kulkarni, Xiuli Liu, Bo Shen
Radiation therapy is a viable option in managing potentially life-threatening malignancies including prostate cancer. It is known that pelvic radiation can result in injury of the distal large bowel with the development of radiation proctitis. Despite reports from retrospective studies, there is a lack of direct endoscopic and histologic evidence of external pelvic radiation injury to the ileal pouch-anal anastomosis. We present a case of a 68-year-old male with pouchitis resulting from pelvic radiation for prostate cancer...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27807556/ileal-pouch-biopsy-triggers-investigation-and-diagnosis-of-systemic-mastocytosis
#13
Abul Ala Syed Rifat Mannan, Bo Shen, Fred Hsieh, Deepa T Patil
We report a unique case of systemic mastocytosis (SM) diagnosed in an ileal pouch biopsy obtained from a 44-year-old woman with ulcerative colitis. She presented with intermittent abdominal pain and watery diarrhea that did not respond to antibiotic therapy. The pouch biopsy showed expansion of the lamina propria by aggregates of CD117 and CD25-positive abnormal mast cells. A subsequent bone marrow analysis showed an increase in abnormal mast cells. Based on World Health Organization criteria, she was diagnosed with SM and responded to cromolyn sodium therapy...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27785322/common-inflammatory-disorders-and-neoplasia-of-the-ileal-pouch-a-review-of-histopathology
#14
REVIEW
David Hernandez Gonzalo, Amy L Collinsworth, Xiuli Liu
Ileal pouch-anal anastomosis (IPAA) is the standard restorative procedure after proctocolectomy in patients with ulcerative colitis (UC) who require colectomy. The ileal pouch is susceptible to a variety of insults including mechanical injury, ischemia, fecal stasis, and infectious agents. In addition, the development of recurrent and idiopathic inflammatory bowel disease and neoplasia may occur in the ileal pouch. Although clinical, endoscopic, and radiographic examination can diagnose many ileal pouch diseases, histologic examination plays an essential role in diagnosis and management, particularly in cases with antibiotic refractory chronic pouchitis and pouch neoplasia...
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27779987/de-novo-crohn-s-disease-after-ileal-pouch-anal-anastomosis-for-ulcerative-colitis-and-inflammatory-bowel-disease-unclassified-long-term-follow-up-of-a-prospective-inflammatory-bowel-disease-registry
#15
Karen Zaghiyan, Jan P Kamiński, Galinos Barmparas, Phillip Fleshner
The risk of de novo Crohn's disease (CD) after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) versus inflammatory bowel disease unclassified (IBDU) or indeterminate colitis (IC) remains debatable. Here, we present updated results after long-term follow-up of a previously studied cohort of 334 patients with UC, IBDU, or IC who underwent IPAA during a 10-year period ending 2007. Of 334 study patients, 56 per cent were male and median age was 38 years (range: 8-81). Patients were classified as UC (n = 237) or IBDU (n = 97) preoperatively and UC (n = 236) or IC (n = 98) postoperatively...
October 2016: American Surgeon
https://www.readbyqxmd.com/read/27755607/correction-micrornas-expression-in-the-ileal-pouch-of-patients-with-ulcerative-colitis-is-robustly-up-regulated-and-correlates-with-disease-phenotypes
#16
Shay Ben-Shachar, Henit Yanai, Hadas Sherman Horev, Hofit Elad, Liran Baram, Ofer Isakov, Hagit Tulchinsky, Metsada Pasmanik-Chor, Noam Shomron, Iris Dotan
[This corrects the article DOI: 10.1371/journal.pone.0159956.].
2016: PloS One
https://www.readbyqxmd.com/read/27734132/bowel-function-in-patients-with-urinary-diversion-a-gender-matched-comparison-of-continent-urinary-diversion-with-the-ileocecal-pouch-and-ileal-conduit
#17
S Frees, A C Schenk, P Rubenwolf, C Ziesel, W Jaeger, J W Thüroff, R Stein
PURPOSE: To evaluate stool habits and associated quality of life (QoL) in a matched pair analysis of patients who underwent continent cutaneous diversion using the ileocecal segment [Mainz pouch I (MzPI)] with an intussuscepted ileal nipple as efferent segment with those receiving an ileal conduit (IC) after radical cystectomy. METHODS: We identified 250 patients who underwent radical cystectomy and urinary diversion (UD) with either MzPI with an ileal nipple or IC in our database...
October 12, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27721922/update-on-medical-and-surgical-options-for-patients-with-acute-severe-ulcerative-colitis-what-is-new
#18
REVIEW
Rachel E Andrew, Evangelos Messaris
Acute severe ulcerative colitis (UC) is a highly morbid condition that requires both medical and surgical management through the collaboration of gastroenterologists and colorectal surgeons. First line treatment for patients presenting with acute severe UC consists of intravenous steroids, but those who do not respond require escalation of therapy or emergent colectomy. The mortality of emergent colectomy has declined significantly in recent decades, but due to the morbidity of this procedure, second line agents such as cyclosporine and infliximab have been used as salvage therapy in an attempt to avoid emergent surgery...
September 27, 2016: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27704203/ileal-pouch-anal-anastomosis-for-ulcerative-colitis-a-canadian-institution-s-experience
#19
E Zittan, Grace W Ma, N Wong-Chong, R Milgrom, R S McLeod, M Silverberg, Z Cohen
BACKGROUND: We aimed to summarize the outcomes of ulcerative colitis (UC) patients receiving an ileal pouch-anal anastamosis (IPAA) over an 11-year period at a high-volume Canadian inflammatory bowel disease (IBD) center. METHODS: A retrospective chart review was performed for subjects with UC who underwent IPAA between 2002 and 2013. Patient charts were reviewed for demographic data, clinical characteristics, preoperative medical treatment, and surgical outcomes...
October 4, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27701840/long-term-outcome-after-ileal-pouch-anal-anastomosis-for-ulcerative-colitis
#20
Dieter Hahnloser, John Pemberton
No abstract text is available yet for this article.
October 2016: ANZ Journal of Surgery
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