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Wound closure

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https://www.readbyqxmd.com/read/29143089/surgical-treatment-of-gastro-pulmonary-fistula-following-bariatric-surgery-possible-and-safe
#1
Alon Ben Nun, David Simansky, Merav Rokah, Nona Zeitlin, Nir Golan, Ramez Abu Khalil, Michalle Soudack
BACKGROUND: Laparoscopic sleeve gastrectomy is a common surgical management of morbid obesity. Major complication rate is 3-8%. Staple line leak is one of the most serious complications. In a small group of patients, a gastro-pulmonary fistula is formed. Endoscopic and minimally invasive measures are the first line of treatment with considerable success rate. There are very poor data in the literature what should be done in cases of failure. In this paper, we report our positive experience with definitive surgical repair...
November 15, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29142601/application-of-spontaneously-closing-cannula-ileostomy-in-laparoscopic-anterior-resection-of-rectal-cancer
#2
Dong Chen, Huiying Zhao, Qiang Huang, Xiangming Xu, Xiaofei Cheng, Bingxin Ke, Danyang Wang, Hanju Hua, Jiahe Xu, Jianjiang Lin, Feng Ye
An anastomotic leak (AL) is the most serious complication observed in laparoscopic anterior resection of rectal cancer (LARRC). In order to protect anastomosis from AL and avoid stoma reversal surgery in patients with ileostomy, spontaneously closing cannula ileostomy (SCCI) was used in LARRC and its safety and feasibility were assessed in the present study. To the best of our knowledge, this is the first time that SCCI has been used in such a case. A total of 41 patients who underwent LARRC with SCCI or ileostomy procedures between November 2013 and August 2014 were retrospectively analyzed...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29142400/chemical-composition-of-moringa-oleifera-ethyl-acetate-fraction-and-its-biological-activity-in-diabetic-human-dermal-fibroblasts
#3
Sivapragasam Gothai, Katyakyini Muniandy, Mazni Abu Zarin, Tan Woan Sean, S Suresh Kumar, Murugan A Munusamy, Sharida Fakurazi, Palanisamy Arulselvan
Background: Moringa oleifera (MO), commonly known as the drumstick tree, is used in folklore medicine for the treatment of skin disease. Objective: The objective of this study is to evaluate the ethyl acetate (EtOAc) fraction of MO leaves for in vitro antibacterial, antioxidant, and wound healing activities and conduct gas chromatography-mass spectrometry (GC-MS) analysis. Materials and Methods: Antibacterial activity was evaluated against six Gram-positive bacteria and 10 Gram-negative bacteria by disc diffusion method...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29141358/-effect-of-different-tourniquet-releasing-strategy-on-blood-loss-in-total-knee-arthroplasty
#4
Y Li, M Lu, H Tian, Z J Li, K Zhang
Objective: To explore the influences on peri-operative blood loss and postoperative blood transfusion in primary total knee arthroplasty when using different methods to release the pneumatic tourniquet. Methods: From January 2015 to December 2016, 484 patients with osteoarthritis were enrolled, undergoing primary unilateral total knee arthroplasty in the Orthopedics Department of Peking University Third Hospital. Retrospective data was used, and all the patients had been operated on by three independent working groups...
November 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29140861/sealing-of-corneal-lacerations-using-photoactivated-rose-bengal-dye-and-amniotic-membrane
#5
Timothy A Soeken, Hong Zhu, Sheri DeMartelaere, Brett W Davies, Mirang Kim, Heuy-Ching Wang, James Aden, Rose Grimm, Clemens Alt, Irene E Kochevar, Anthony J Johnson
PURPOSE: Watertight closure of perforating corneoscleral lacerations is necessary to prevent epithelial ingrowth, infection, and potential loss of the eye. Complex lacerations can be difficult to treat, and repair with sutures alone is often inadequate. In this study, we evaluated a potentially sutureless technology for sealing complex corneal and scleral lacerations that bonds the amniotic membrane (AM) to the wound using only green light and rose bengal dye. METHODS: The AM was impregnated with rose bengal and then sealed over lacerations using green light to bond the AM to the deepithelialized corneal surface...
November 14, 2017: Cornea
https://www.readbyqxmd.com/read/29138380/-three-patients-with-gastric-cancer-who-underwent-surgery-during-ramucirumab-treatment
#6
Hayato Omori, Sadayuki Kawai, Rie Makuuchi, Tomoyuki Irino, Masanori Tokunaga, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Hirofumi Yasui, Masanori Terashima
According to the REGARD and RAINBOW trials, ramucirumab(RAM)was introduced as second-line therapy for advanced or metastatic gastric cancer. RAM may impair wound healing due to the inhibition of angiogenesis; details on the postoperative course of patients who underwent surgery during RAM treatment remain unclear. Between 2011 and 2016, 93 patients with incurable gastric cancer were treated with RAM in our institute. Among them, 3 patients underwent surgery after RAM treatment. Case 1: A 74-year-old man with liver metastasis from gastric cancer was treated with a paclitaxel(PTX)plus RAM regimen...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29137568/first-dorsal-metatarsal-artery-perforator-flap-to-cover-great-toe-defect
#7
Roongsak Limthongthang, Perajit Eamsobhana
BACKGROUND: There were very few options available for distal foot and toe defects that required a vascularized flap for coverage. As such, the use of a free flap was often justified in this region of the foot. The use of perforator flaps has created a new subset of local tissue transfer alternatives that increases the potential that the difficulties associated with microvascular tissue transfers could be avoided. The first dorsal metatarsal artery (FDMA) perforator flap was one variant of this new type of tissue transfer...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29136259/risk-factors-for-surgical-site-infections-in-dermatological-surgery
#8
Xiaomeng Liu, Melissa Sprengers, Patty J Nelemans, Klara Mosterd, Nicole W J Kelleners-Smeets
Current literature on risk factors for surgical site infection (SSI) in dermatological surgery in the absence of antibiotic prophylaxis is limited. The aim of this study was to retrospectively evaluate patients presenting for dermatological surgery. A total of 1,977 procedures were reviewed. SSI was clinically suspected in 79 (4.0%) patients and confirmed by culture in 38 (1.9%). Using the strictest definition of SSI (clinical symptoms with positive culture) significantly higher risk of SSI was found for location on the ear (odds ratio (OR) 6...
November 14, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29135272/-protecting-the-inferior-alveolar-nerve-coronectomy-of-lower-third-molars-review
#9
József Szalma, Edina Lempel
Coronectomy of lower impacted wisdom teeth is the partial removal of third molars, aiming to avoid inferior alveolar nerve injuries. The coronectomy procedure has several crucial points, such as the pulpal, periapical preoperative conditions of the tooth, the way of crown sectioning and decoronation, the wound closure and the length of patients' follow up. In addition it is important to identify and manage possible intraoperative or postoperative complications correctly. According to the literature, the complication rate of coronectomy is usually lower, than that of total teeth removal, furthermore considering inferior alveolar nerve injuries, coronectomy is significantly the safer procedure...
November 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29133970/laser-and-platelet-rich-plasma-to-treat-medication-related-osteonecrosis-of-the-jaws-mronj-a-case-report
#10
Carlo Fornaini, Luigi Cella, Aldo Oppici, Anna Parlatore, Fabio Clini, Matteo Fontana, Giuseppe Lagori, Elisabetta Merigo
Aims: The appropriate management of Medication-Related OsteoNecrosis of the Jaw (MRONJ) is still a challenge for dentists and oral surgeons and in these last years high-technology instruments have been proposed at the different steps of interventions, also combined with promoters of tissue repair.The aim of this report is to show the advantages of a combined approach (laser and PRP) for the treatment of MRONJ. Methods: It is described the case of a patient positive for MRONJ observed at the Odontostomatology and Maxillo-Facial Surgery Unit of the Hospital of Piacenza where surgical approach was performed by using different devices: Er:YAG laser (2940 nm) to remove and vaporize necrotic hard tissue until bleeding bone; Platelet-Rich Plasma (PRP) to stimulate hard and soft tissue healing; diode laser (808 nm) to biostimulate the surgical site...
September 30, 2017: Laser Therapy
https://www.readbyqxmd.com/read/29132116/the-outcome-of-laparoscopic-subtotal-cholecystectomy-in-difficult-cases-a-case-series
#11
Caroline Supit, Tommy Supit, Yarman Mazni, Ibrahim Basir
INTRODUCTION: Laparoscopic subtotal cholecystectomy (LSC) is a widely used technique for managing cholelithiasis with severe cholecystitis. The increasing popularity its utilization is due to the good safety profile and acceptable results. This case series evaluates the short- and long-term results of Indonesian patients who underwent LSC with an objective to determine whether the procedure can be a standard approach for difficult cholecystectomy in our institution. PRESENTATION OF CASE: Thirty-four Indonesian patients (26 men, 8 women) with the mean age of 54...
November 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29131752/surfactants-and-their-role-in-wound-cleansing-and-biofilm-management
#12
S L Percival, D Mayer, M Malone, T Swanson, D Gibson, G Schultz
Surfactants are widely used as detergents, emulsifiers, wetting agents, foaming agents and dispersants in the cosmetics, hygiene, food and oil industries. Their use in a clinical setting is also common, particularly within the field of wound care. Many wound cleansers contain surfactants and subsequently there is available data that shows the growing potential of these wound cleansers in the enhancement of wound closure. The presence of microorganisms in wounds has been recognised as a significant factor that delay healing...
November 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29131751/a-diabetic-foot-ulcer-treated-with-hydrogel-and-hyperbaric-oxygen-therapy-a-case-study
#13
P Aguiar, C Amaral, A Rodrigues, A H de Souza
This study reports on the case of an elderly patient, with diabetes, and a bullous wound on the left big toe that led to an amputation of the first and second left toes. The amputation was because of deep injury as it was not able to heal with a conventional treatment. After completing the normal treatment and the removal of a bacterial infection in the lesion, the patient underwent a treatment that was based on a hydrogel gel (0.9% saline solution) and hyperbaric oxygen therapy (HBOT). After 60 sessions of the therapy, almost complete closure of the wound was observed...
November 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29129266/single-cell-defects-cause-a-long-range-mechanical-response-in-a-confluent-epithelial-cell-layer
#14
Susanne Karsch, Deqing Kong, Jörg Großhans, Andreas Janshoff
Epithelial cells are responsible for tissue homeostasis and form a barrier to maintain chemical gradients and mechanical integrity. Therefore, rapid wound closure is crucial for proper tissue function and restoring homeostasis. In this study, the mechanical properties of cells surrounding a single-cell wound are investigated during closure of the defect. The single-cell wound is induced in an intact layer using micropipette action and responses in neighboring cells are monitored with atomic force microscopy...
November 9, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/29126392/mir-17-5p-suppresses-cell-proliferation-and-invasion-by-targeting-etv1-in-triple-negative-breast-cancer
#15
Jie Li, Yuanhui Lai, Jieyi Ma, Yue Liu, Jiong Bi, Longjuan Zhang, Lianzhou Chen, Chen Yao, Weiming Lv, Guangqi Chang, Shenming Wang, Mao Ouyang, Wenjian Wang
BACKGROUND: Triple-negative breast cancer (TNBC) is the malignancy with the worst outcome among all breast cancer subtypes. We reported that ETV1 is a significant oncogene in TNBC tumourigenesis. Consequently, investigating the critical regulatory microRNAs (miRNAs) of ETV1 may be beneficial for TNBC targeted therapy. METHODS: We performed in situ hybridization (ISH) and immunohistochemistry (IHC) to detect the location of miR-17-5p and ETV1 in TNBC patient samples, respectively...
November 10, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29126044/medial-forefoot-fillet-flap-for-primary-closure-of-transmetatarsal-amputation-a-series-of-four-cases
#16
Eliezer Sidon, Shai Shemesh, Yoav Rosenthal, Snir Heller, Steven Velkes, Alon Burg
Amputation of the forefoot is a salvage procedure for several forefoot acute or chronic infection. A good, sensate and durable skin cover is important for quicker and better rehabilitation. The use of filleted flaps (or "spare parts technique") has been published in the past as a creative technique. The purpose of this article is to introduce a reproducible, pre-planned, technique that requires less creativity for the use of the "spare parts". The authors describe a case series of 4 patients with deep infection and osteomyelitis of the forefoot, without involvement of the medial skin that underwent two staged procedure for transmetatarsal amputation with medial forefoot fillet flap...
June 29, 2017: Foot
https://www.readbyqxmd.com/read/29126042/successful-treatment-of-infected-wound-dehiscence-after-minimally-invasive-locking-plate-osteosynthesis-of-tibial-pilon-and-calcaneal-fractures-by-plate-preservation-surgical-debridement-and-antibiotics
#17
Giandavide Ieropoli, Jorge Hugo Villafañe, Silvia Chiara Zompi, Umberto Morozzo, Riccardo D'Ambrosi, Federico Giuseppe Usuelli, Pedro Berjano
OBJECTIVE: The aim is to present a case series that illustrates possible benefits from combining minimally invasive plate osteosynthesis (MIPO), plastic surgery and antibiotic therapy, in order to treat and eradicate infection in patients with tibial pilon or calcaneal fractures. METHODS: Eleven consecutive patients with dehiscence of the surgical wound in outcomes MIPO using a Locking Compression Plate (LCP) for tibial pilon, or calcaneus fractures. The patients had developed a documented infection of the surgical wound...
October 23, 2017: Foot
https://www.readbyqxmd.com/read/29124954/practicality-of-using-the-figure-of-eight-bandage-to-prevent-fatal-wound-dehiscence-after-spinal-tumor-surgery-for-upper-thoracic-metastasis
#18
Dong Kwang Seo, Jin-Hoon Park, Sun Kyu Oh, Yongchel Ahn, Sang Ryong Jeon
OBJECT: Serious postoperative wound problems can frequently develop after surgery with perioperative RT for upper thoracic metastatic lesions. The figure-of-eight bandage can restrict excessive shoulder motion, which could prevent wound dehiscence. The purpose of this study was to describe the efficacy of using the figure-of-eight bandage to prevent postoperative wound dehiscence. METHODS: Between February 2005 and July 2015, we retrospectively evaluated the medical records of cancer patients who underwent surgery with or without RT for spinal metastasis involving the upper thoracic spine...
November 10, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29124855/reconstructive-options-for-large-back-free-flap-donor-sites
#19
Arshia Azizeddin, Peter F M Choong, Damien Grinsell
BACKGROUND: Reconstruction of posterior thoracic and trunk defects can prove challenging even to the most seasoned surgeons. Many commonly used techniques for closing back defects include primary closure and split skin grafts. Often times, however, other techniques are needed in order to give the patient the best aesthetic and functional outcome. In this study, we focus on and evaluate donor site closure techniques for defects in the back created by harvesting scapular and parascapular flaps...
November 9, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29123376/intracameral-ketorolac-concentration-at-the-beginning-and-end-of-cataract-surgery-following-preoperative-topical-ketorolac-administration
#20
Douglas A Katsev, Cailyn C Katsev, Jen Pinnow, Catherine M Lockhart
Purpose: To evaluate the intracameral concentration of ketorolac tromethamine (ketorolac) at the beginning and end of cataract surgery following preoperative topical administration. Setting: Santa Barbara Surgery Center, Santa Barbara, CA, USA. Design: This was a pre-post, interventional, single-arm study. Patients and methods: Patients undergoing cataract extraction and lens replacement (CELR) were eligible. Written informed consent was obtained from 14 patients who were prescribed topical ophthalmic ketorolac according to the surgeon's usual practice beginning the day prior to surgery...
2017: Clinical Ophthalmology
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