keyword
https://read.qxmd.com/read/38310479/comparative-effectiveness-of-oral-hypoglycemic-agents-for-glycemic-control-and-glycemic-variability-in-patients-with-type-2-diabetes-mellitus-using-flash-glucose-monitoring
#21
JOURNAL ARTICLE
Poongothai Venkatachalapathy, Karthik Kumar Dos Alagarswamy Mohandoss, Murali Munisamy, Mohan Sellappan
AIM: The study aimed to compare the effectiveness of oral hypoglycemic agents (OHAs) as monotherapy, dual and quadruple therapy for glycemic control (GC) and glycemic variability (GV) in patients with type-2 diabetes (T2DM) using flash glucose monitoring system (FGM). BACKGROUND: Diabetes management largely relies on HbA1c monitoring. Glycemic variability (GV) has been an evolving glycemic target for preventing complications related to type 2 diabetes mellitus (T2DM)...
January 16, 2024: Current Diabetes Reviews
https://read.qxmd.com/read/38307489/assessment-of-the-quality-diagnosis-and-therapeutic-recommendations-of-clinical-practice-guidelines-on-patients-with-helicobacter-pylori-infection-a-systematic-review
#22
REVIEW
Muyang Li, Xueni Ma, Xu Huimei, Mengyu Han, Lingzhu Gou, Du Hongwei, Lina Wei, Dekui Zhang
We conducted this study to systematically review and assess the current clinical practice guidelines (CPGs) related to the diagnosis and treatment of Helicobacter pylori (H. pylori) infection. The aim was to evaluate the quality of these included CPGs and provide clinicians with a convenient and comprehensive reference for updating their own CPGs. We searched four databases to identify eligible CPGs focusing on H. pylori diagnosis and treatment recommendations. The results were presented using evidence mappings...
January 31, 2024: Gastroenterología y Hepatología
https://read.qxmd.com/read/38291932/-continuing-medical-education-cme-ecm-on-medical-devices-in-italy-a-review-for-the-2019-2021-period
#23
JOURNAL ARTICLE
Anna Maria Vincenza Amicosante, Erica Eugeni, Fabio Bernardini, Antonella Vincenza Cavallo, Simona Paone, Elisa Guglielmi, Marco Marchetti, Giovanni Baglio
INTRODUCTION: Health technology assessment (Hta) is a multidisciplinary process that uses explicit methods to determine the value of a health technology across various domains. It aims at supporting decision-makers in promoting an equitable, efficient, and high-quality healthcare system. During 2023, the Italian Minister of Health officially endorsed the National program for Hta on medical devices 2023-2025 (Pnhta), aligning with EU Regulation 2017/745 and EU Regulation 2017/746. A key objective of Pnhta is to launch a continuous training initiative targeting all professionals within the Italian Health Service to enhance their knowledge and usability of Hta...
February 2024: Recenti Progressi in Medicina
https://read.qxmd.com/read/38289779/down-syndrome-screening-among-pregnant-women-visiting-the-department-of-obstetrics-and-gynaecology-of-a-tertiary-care-centre
#24
JOURNAL ARTICLE
Jyotshna Sharma, Meena Thapa, Ranjana Yadav, Dipty Shrestha
INTRODUCTION: The screening of Down's syndrome by the measurement of serum markers using dual and quadruple tests in the second trimester is done among obstetric patients between 13 to 22 weeks of gestation. The test readings are signified in terms of low-risk or high-risk. The aim of this study was to find out the prevalence of Downs syndrome screening among pregnant women visiting the Department of Obstetrics and Gynaecology of a tertiary care centre. METHODS: A descriptive cross-sectional study was conducted from 15 April 2022 to 15 December 2022 among patients visiting the Department of Obstetrics and Gynecology of a tertiary care centre...
October 1, 2023: JNMA; Journal of the Nepal Medical Association
https://read.qxmd.com/read/38284706/pharmacological-treatment-of-heart-failure-recent-advances
#25
JOURNAL ARTICLE
Jonathan C H Chan, Areeb Siddiqui
BACKGROUND: Heart failure is a clinical condition with high mortality and morbidity that occurs when the heart is unable to pump enough blood to meet the metabolic demands of the body. The pharmacological management of heart failure has been revolutionized over the past decade with novel treatments. OBJECTIVE: The aim of the review is to highlight the recent pharmacological advances in the management of heart failure. RESULTS: Sodium-glucose cotransporter-2 inhibitor (SGLT2i), iron carboxymaltose, finerenone, omecamtiv mecarbil, and vericiguat have been shown to reduce hospitalization for heart failure...
January 26, 2024: Current Cardiology Reviews
https://read.qxmd.com/read/38279516/estimating-the-clinical-and-budgetary-impact-of-using-angiotensin-receptor-neprilysin-inhibitor-as-first-line-therapy-in-patients-with-hfref
#26
JOURNAL ARTICLE
Nicklas Bergh, Krister Lindmark, Johannes Lissdaniels, Gustav Lanne, Oskar Käck, Martin R Cowie
AIMS: Recent updates of international treatment guidelines for heart failure with reduced ejection fraction (HFrEF) differ regarding the use of angiotensin receptor neprilysin inhibitor (ARNI) as first-line treatment. The American Heart Association/American College of Cardiology/Heart Failure Society of America (AHA/ACC/HFSA) 2022 guidelines gives ARNI a Class IA recommendation for HFrEF patients while the European Society of Cardiology's guidelines are less clear when ARNI could be considered as first line treatment option in de novo patients...
January 26, 2024: ESC Heart Failure
https://read.qxmd.com/read/38276175/independent-risk-factors-predicting-eradication-failure-of-hybrid-therapy-for-the-first-line-treatment-of-helicobacter-pylori-infection
#27
JOURNAL ARTICLE
Chien-Lin Chen, I-Ting Wu, Deng-Chyang Wu, Wei-Yi Lei, Feng-Woei Tsay, Seng-Kee Chuah, Kuan-Yang Chen, Jyh-Chin Yang, Yu-Hwa Liu, Chao-Hung Kuo, Sz-Iuan Shiu, Chang-Bih Shie, Kuan-Hua Lin, Chia-Long Lee, Ping-I Hsu
Hybrid therapy is a recommended first-line anti- H. pylori treatment option in the American College of Gastroenterology guidelines, the Bangkok Consensus Report on H. pylori management, and the Taiwan H. pylori Consensus Report. However, the cure rates of eradication therapy in some countries are suboptimal, and the factors affecting the treatment efficacy of hybrid therapy remain unclear. The aim of this study is to identify the independent risk factors predicting eradication failure of hybrid therapy in the first-line treatment of H...
December 19, 2023: Microorganisms
https://read.qxmd.com/read/38271393/consumer-objective-and-subjective-knowledge-about-healthy-foods-an-approach-to-promote-healthy-lifestyle-choices-in-south-africa
#28
JOURNAL ARTICLE
Daleen van der Merwe, Hanli de Beer, Susanna Ellis, Petra Bester, Frederick Marais, Adri Steyn
Unhealthy food choices and consumption, coupled with sedentary lifestyles among consumers, intensify public health concerns regarding the quadruple disease burden, despite Primary Health Care (PHC) policy. However, the current relationship between consumer knowledge about healthy foods and following a healthy lifestyle needs to be explored. Our study, therefore, aimed to determine the association between consumers' subjective and objective knowledge about healthy foods and various healthy lifestyle choices...
2024: PloS One
https://read.qxmd.com/read/38271097/digital-transformation-of-public-health-for-noncommunicable-diseases-narrative-viewpoint-of-challenges-and-opportunities
#29
JOURNAL ARTICLE
Onicio Leal Neto, Viktor Von Wyl
The recent SARS-CoV-2 pandemic underscored the effectiveness and rapid deployment of digital public health interventions, notably the digital proximity tracing apps, leveraging Bluetooth capabilities to trace and notify users about potential infection exposures. Backed by renowned organizations such as the World Health Organization and the European Union, digital proximity tracings showcased the promise of digital public health. As the world pivots from pandemic responses, it becomes imperative to address noncommunicable diseases (NCDs) that account for a vast majority of health care expenses and premature disability-adjusted life years lost...
January 25, 2024: JMIR Public Health and Surveillance
https://read.qxmd.com/read/38258243/design-of-a-micro-electro-mechanical-system-quad-mass-gyroscope-with-compliant-mechanical-amplification
#30
JOURNAL ARTICLE
Jingchuan Zhou, Dacheng Xu, Xinxin Li, Fang Chen
In this work, a novel mechanical amplification structure for a MEMS vibratory gyroscope is proposed with the aim of improving their sensitivity. The scheme is implemented using a system of micromachined V-shaped springs as a deflection amplifying mechanism. The effectiveness of the mechanism is first demonstrated for a capacitive fully decoupled quad mass gyroscope. A proof of concept vertical-axis mechanically amplified gyroscope with an amplification factor of 365% has been designed, simulated and fabricated, and results from its evaluation are presented in this paper...
January 11, 2024: Micromachines
https://read.qxmd.com/read/38223245/-helicobacter-pylori-infection-diagnosis-and-management-current-practices-of-greek-gastroenterologists
#31
JOURNAL ARTICLE
Adonis A Protopapas, Ioanna Papagiouvanni, Andreas N Protopapas, Ioannis Goulis
BACKGROUND: The diagnosis and management of Helicobacter pylori ( H. pylori ) infection vary significantly, depending on country, area, and specialty. The aim of this study was to record the current practices of Greek gastroenterologists in the screening and treatment of H. pylori infection. METHOD: An anonymous questionnaire consisting of 19 questions about the management of H. pylori infection was sent with the aid of the Hellenic Society of Gastroenterology to all members of the Society...
2024: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://read.qxmd.com/read/38195152/establishing-cost-effectiveness-threshold-in-china-a-community-survey-of-willingness-to-pay-for-a-healthylife-year
#32
JOURNAL ARTICLE
Lizheng Xu, Mingsheng Chen, Blake Angell, Yawen Jiang, Kirsten Howard, Stephen Jan, Lei Si
INTRODUCTION: The willingness to pay per quality-adjusted life year gained (WTP/Q) is commonly used to determine whether an intervention is cost-effective in health technology assessment. This study aimed to evaluate the WTP/Q for different disease scenarios in a Chinese population. METHODS: The study employed a quadruple-bounded dichotomous choice contingent valuation method to estimate the WTP/Q in the general public. The estimation was conducted across chronic, terminal and rare disease scenarios...
January 9, 2024: BMJ Global Health
https://read.qxmd.com/read/38180456/cost-effectiveness-of-new-quadruple-therapy-compared-with-standard-treatment-for-patients-with-heart-failure-in-china
#33
JOURNAL ARTICLE
Yun Huang, Hua Zhou, Chongbo Fang, Lili Ma, Yuyu Zhang, Weibo Rong, Xiaoli Liu, Honghua Ye
This study aimed to compare the cost-effectiveness of the new quadruple therapy regimen of adding sodium-glucose-linked transporter 2 (SGLT2) inhibitors, with standard treatment for patients with heart failure (HF) in China. From the payer's perspective, the dates of cardiovascular event recurrences were extracted from a meta-analysis including 6 trials, combined with the treatment cost for patients with HF in China to construct a Markov model. The outcomes included per capita medical costs and incremental cost-effectiveness ratio, using quality-adjusted life years (QALYs) data...
January 1, 2024: Journal of Cardiovascular Pharmacology
https://read.qxmd.com/read/38176730/artificial-intelligence-in-the-future-landscape-of-pediatric-neuroradiology-opportunities-and-challenges
#34
JOURNAL ARTICLE
Aashim Bhatia, Farzad Khalvati, Birgit Betina Ertl-Wagner
This paper will review how artificial intelligence (AI) will play an increasingly important role in pediatric neuroradiology in the future. A safe, transparent, and human-centric AI is needed to tackle the quadruple aim of improved health outcomes, enhanced patient and family experience, reduced costs, and improved well-being of the healthcare team in pediatric neuroradiology. Equity, diversity and inclusion, data safety, and access to care will need to always be considered. In the next decade, AI algorithms are expected to play an increasingly important role in access to care, workflow management, abnormality detection, classification, response prediction, prognostication, report generation, as well as in the patient and family experience in pediatric neuroradiology...
January 4, 2024: AJNR. American Journal of Neuroradiology
https://read.qxmd.com/read/38166812/evidence-on-bringing-specialised-care-to-the-primary-level-effects-on-the-quadruple-aim-and-cost-effectiveness-a-systematic-review
#35
JOURNAL ARTICLE
Maria Lovén, Laura J Pitkänen, Markus Paananen, Paulus Torkki
BACKGROUND: To achieve the Quadruple Aim of improving population health, enhancing the patient experience of care, reducing costs and improving professional satisfaction requires reorganisation of health care. One way to accomplish this aim is by integrating healthcare services on different levels. This systematic review aims to determine whether it is cost-effective to bring a hospital specialist into primary care from the perspectives of commissioners, patients and professionals. METHODS: The review follows the PRISMA guidelines...
January 2, 2024: BMC Health Services Research
https://read.qxmd.com/read/38143795/asynchronous-telemedicine-a-systematic-literature-review
#36
REVIEW
Nathan Culmer, Todd Brenton Smith, Catanya Stager, Andrea Wright, Abigail Fickel, Jet Tan, Carlos Trey Clark, Hannah Meyer, Katherine Grimm
BACKGROUND: Asynchronous telemedicine (ATM), which describes telemedical interaction between a patient and provider where neither party communicates simultaneously, is an important telemedicine modality that is seeing increased use. In this article, we summarize the published peer-reviewed literature specifically related to ATM to (1) identify terms or phrases that are used to describe ATM, (2) ascertain how this research has thus far addressed the various aspects of the quadruple aim of medicine, and (3) assess the methodological rigor of research on ATM...
2023: Telemedicine reports
https://read.qxmd.com/read/38133906/real-time-virtual-support-as-an-emergency-department-strategy-for-rural-remote-and-indigenous-communities-in-british-columbia-descriptive-case-study
#37
JOURNAL ARTICLE
Helen Novak Lauscher, Brydon Blacklaws, Erika Pritchard, Elsie Jiaxi Wang, Kurtis Stewart, Jeff Beselt, Kendall Ho, John Pawlovich
BACKGROUND: British Columbia has over 200 rural, remote, and Indigenous communities that have limited health care resources due to physician isolation, sparsity in clinical resources, the lack of collegial support, and provider burnout. Real-time virtual support (RTVS) peer-to-peer pathways provide support to patients and providers. Amid the COVID-19 pandemic exacerbating existing health care disparities and equitable access to timely care, RTVS presents a portable and additional opportunity to be deployed in a hospital or patient home setting in rural communities...
December 22, 2023: Journal of Medical Internet Research
https://read.qxmd.com/read/38129806/efficacy-comparison-of-7-and-14-day-p-cab-based-bismuth-containing-quadruple-regimen-with-ppi-based-bismuth-containing-quadruple-regimen-for-helicobacter-pylori-infection-rationale-and-design-of-an-open-label-multicenter-randomized-controlled-trial
#38
JOURNAL ARTICLE
Chang Kyo Oh, Hyun Lim, Seung In Seo, Sang Pyo Lee, Chang Seok Bang, Woon Geon Shin, Jin Bae Kim, Hyun Joo Jang, Gwang Ho Baik
BACKGROUND: Owing to its strong acid inhibition, potassium-competitive acid blocker (P-CAB) based regimens for Helicobacter pylori (H. pylori) eradication are expected to offer clinical advantages over proton pump inhibitor (PPI) based regimens. This study aims to compare the efficacy and adverse effects of a 7-day and a 14-day P-CAB-based bismuth-containing quadruple regimen (PC-BMT) with those of a 14-day PPI-based bismuth-containing quadruple regimen (P-BMT) in patients with high clarithromycin resistance...
December 21, 2023: BMC Gastroenterology
https://read.qxmd.com/read/38084126/enhancing-the-biopharmacological-characteristics-of-asperosaponin-vi-unveiling-dynamic-self-assembly-phase-transitions-in-the-gastrointestinal-environment
#39
JOURNAL ARTICLE
Yulin Mo, Yanjun Yang, Jingqi Zeng, Weikun Ma, Yuxin Guan, Jingxi Guo, Xiaochun Wu, Dingkun Liu, Liang Feng, Xiaobin Jia, Bing Yang
PURPOSE: Asperosaponin VI (ASP VI) as an active ingredient of Dipsacus asperoides , which has a wide range of biological and pharmacological activity. However, its development and application are restricted due to the poor gastrointestinal permeability and oral bioavailability. This investigation aims to reveal the influence of the self-assembled structure by the interaction between ASP VI and endogenous components NaTC and/or DOPC in the gastrointestinal environment on its biopharmaceutical properties, and novelty elucidated the molecular mechanism for the formation of self-assembled nanomicelles...
2023: International Journal of Nanomedicine
https://read.qxmd.com/read/38072901/wide-bovine-tick-borne-pathogen-spectrum-predominancy-of-theileria-annulata-and-the-first-molecular-detection-of-ehrlichia-minasensis-in-turkey
#40
JOURNAL ARTICLE
Onur Ceylan, Zhuowei Ma, Ceylan Ceylan, Muhammed Hudai Culha, Eloiza May Galon, Shengwei Ji, Hang Li, Iqra Zafar, Uday Kumar Mohanta, Xuenan Xuan, Ferda Sevinc
Vector-borne diseases indulge in severe economic losses in the livestock industry by adversely affecting cattle breeding in tropical and subtropical zone countries, including Turkey, encompassing a wide land area representing diverse climatic conditions. This study aimed to investigate significant bovine tick-borne piroplasm, rickettsia, and some other bacterial agents by genus- or species-specific PCR and nested PCR techniques in Turkey. A total of 210 cattle blood samples were collected from sixteen provinces in different geographical regions of Turkey...
December 11, 2023: Veterinary Research Communications
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