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Valve prosthesis children

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https://www.readbyqxmd.com/read/27436872/valve-sparing-root-replacement-in-children
#1
Jolanda Kluin, David R Koolbergen, Vladimir Sojak, Mark G Hazekamp
OBJECTIVES: In children, words of caution have been raised about valve-sparing procedures especially regarding the valve-remodelling technique. This study reviewed our experience with the valve-sparing reimplantation technique in children. METHODS: All consecutive paediatric (<18 years) patients who underwent valve-sparing root replacement in our centre in the past 12.5 years were retrospectively analysed. RESULTS: Nineteen patients (median age 13...
September 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27345614/biomechanics-drive-histological-wall-remodeling-of-neoaortic-root-a-mathematical-model-to-study-the-expression-levels-of-ki-67-metalloprotease-and-apoptosis-transition
#2
Francesco Nappi, Massimiliano Fraldi, Cristiano Spadaccio, Angelo Rosario Carotenuto, Stefania Montagnani, Clotilde Castaldo, Juan Carlos Chachques, Christophe Acar
The pulmonary artery autograft (PA) is the ideal substitute for aortic valve disease in children and young adult. However, it is harnessed by the issue of long-term dilation and regurgitation, often requiring surgery. PA implanted in aortic position during the growth phase in children undergoes a process of mechanical remodeling. We previously developed a semiresorbable armored prosthesis able to mechanically sustain the neoaorta preventing dilation and to gradually integrate with the PA wall inducing a progressive arterial-like tissue positive remodeling...
November 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27060049/mechanical-pulmonary-valve-replacement
#3
REVIEW
John M Stulak, Bassem N Mora, Sameh M Said, Hartzell V Schaff, Joseph A Dearani
Although most valve operations performed annually address lesions of the aortic or mitral valves, the frequency of pulmonary valve replacement (PVR) is increasing because most patients with congenital heart disease are surviving into the adult years. The vast majority of patients, especially children that require PVR, obtain a tissue valve because of the relative good durability and the lack of a need for anticoagulation. Because the need for repeat operation is inevitable for most patients, and the population of adults with congenital heart disease continues to grow, there are increasing situations in which a mechanical pulmonary prosthesis may be appropriate...
2016: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://www.readbyqxmd.com/read/27041455/ross-versus-non-ross-aortic-valve-replacement-in-children-a-22-year-single-institution-comparison-of-outcomes
#4
John W Brown, Parth M Patel, Jiuann-Huey Ivy Lin, Asma S Habib, Mark D Rodefeld, Mark W Turrentine
BACKGROUND: The Ross aortic valve replacement (AVR) has been the AVR of choice for children at our center since 1993. Absence or inadequate quality of the pulmonary valve or, less commonly, family or surgeon preference caused us to select an alternative AVR prosthesis for some children. This review compares the outcomes of 42 children who received a non-Ross AVR with 115 children undergoing Ross root replacement at our institution during the most recent 22 years. METHODS: A retrospective chart review of the 42 pediatric non-Ross AVRs was compared with 115 Ross AVRs...
May 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26897842/degenerative-calcification-of-pericardial-bioprostheses-comparison-of-five-implantation-methods-in-a-rabbit-model
#5
COMPARATIVE STUDY
Dai-Hyun Kim, Han Ki Park, Young Hwan Park, Seung Hyun Lee, Hyun-Chel Joo, Sak Lee, Young-Nam Youn, Hong Ju Shin
BACKGROUND AND AIM OF THE STUDY: The degenerative calcification of bioprosthetic heart valves remains a clinical challenge, especially among young adults and children. Animal models that are based on subcutaneous and intramuscular implantation and are typically used to assess interventions to prevent bioprosthetic heart valve calcification do not reflect actual hemodynamic stress and lack direct blood contact. Thus, the study aim was to investigate bioprosthesis calcification at different implantation sites...
September 2015: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/26896320/decellularized-aortic-homografts-for-aortic-valve-and-aorta-ascendens-replacement
#6
Igor Tudorache, Alexander Horke, Serghei Cebotari, Samir Sarikouch, Dietmar Boethig, Thomas Breymann, Philipp Beerbaum, Harald Bertram, Mechthild Westhoff-Bleck, Karolina Theodoridis, Dmitry Bobylev, Eduard Cheptanaru, Anatol Ciubotaru, Axel Haverich
OBJECTIVES: The choice of valve prosthesis for aortic valve replacement (AVR) in young patients is challenging. Decellularized pulmonary homografts (DPHs) have shown excellent results in pulmonary position. Here, we report our early clinical results using decellularized aortic valve homografts (DAHs) for AVR in children and mainly young adults. METHODS: This prospective observational study included all 69 patients (44 males) operated from February 2008 to September 2015, with a mean age of 19...
July 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/26652571/surgery-for-semilunar-valve-regurgitation-during-ventricular-assist-device-support-in-children
#7
Massimo Padalino, Giacomo Bortolussi, Nicola Maschietto, Alvise Guariento, Giovanni Stellin
Semilunar valve regurgitation (SVR) in children on ventricular assist device (VAD) support is a difficult task. Three children with SVR prior or during VAD support, underwent uneventful semilunar valve surgery, and 2 patients were successfully bridged to heart transplantation. We conclude that surgical management of SVR during VAD support in children is feasible with low operative risk, and is mandatory to optimize VAD support while on waiting list.
December 2015: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26552510/cost-comparison-of-transcatheter-and-operative-pulmonary-valve-replacement-from-the-pediatric-health-information-systems-database
#8
MULTICENTER STUDY
Michael L O'Byrne, Matthew J Gillespie, Russell T Shinohara, Yoav Dori, Jonathan J Rome, Andrew C Glatz
Outcomes for transcatheter pulmonary valve replacement (TC-PVR) and operative pulmonary valve replacement (S-PVR) are excellent. Thus, their respective cost is a relevant clinical outcome. We performed a retrospective cohort study of children and adults who underwent PVR at age ≥ 8 years from January 1, 2011, to December 31, 2013, at 35 centers contributing data to the Pediatric Health Information Systems database to address this question. A propensity score-adjusted multivariable analysis was performed to adjust for known confounders...
January 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/26541831/outcome-after-aortic-valve-replacement-in-children-a-systematic-review-and-meta-analysis
#9
REVIEW
Jonathan R G Etnel, Lisa C Elmont, Ebru Ertekin, M Mostafa Mokhles, Helena J Heuvelman, Jolien W Roos-Hesselink, Peter L de Jong, Willem A Helbing, Ad J J C Bogers, Johanna J M Takkenberg
OBJECTIVE: Despite an increasing interest in pediatric aortic valve repair, aortic valve replacement in children may be unavoidable. The evidence on outcome after pediatric aortic valve replacement is limited and usually reported in small case series. This systematic review and meta-analysis aims to provide an overview of reported outcome of pediatric patients after aortic valve replacement. METHODS: A systematic literature search for publications reporting outcome after pediatric aortic valve replacement published between January 1990 and May 2015 was conducted...
January 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26541279/effect-of-pulmonary-conduit-oversizing-on-hemodynamics-in-children
#10
Simon J Sonntag, Maximilan Kütting, Pejman Farhadi Ghalati, Tim Kaufmann, Jaime Vázquez-Jiménez, Ulrich Steinseifer, Janez Vodiskar
PURPOSE: Implanting the largest valved conduit possible - oversizing - to reconstruct an absent connection from the right ventricle to the pulmonary artery in certain types of congenital heart defects has been suggested as a compensating measure for somatic outgrowth of the patient. However, one effect that has not been investigated yet is the hemodynamic consequence. For this purpose, virtual implantation and flow simulations were conducted in this study. METHODS: To isolate the effects of conduit oversizing on the hemodynamics observed after conduit implantation and outgrowth, calculated wall shear stresses (WSS) of image-based computational fluid dynamic (CFD) simulations were used as indicators...
October 2015: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/26519248/options-for-aortic-valve-replacement-in-children-and-young-adults-okay-doctor-but-which-one-do-you-think-i-should-choose
#11
EDITORIAL
Osman O Al-Radi
No abstract text is available yet for this article.
January 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26399177/heart-valve-tissue-engineering-how-far-is-the-bedside-from-the-bench
#12
REVIEW
Andres Sanz-Garcia, Jorge Oliver-de-la-Cruz, Vicente Mirabet, Carolina Gandía, Alejandro Villagrasa, Enrique Sodupe, Carmen Escobedo-Lucea
Heart disease, including valve pathologies, is the leading cause of death worldwide. Despite the progress made thanks to improving transplantation techniques, a perfect valve substitute has not yet been developed: once a diseased valve is replaced with current technologies, the newly implanted valve still needs to be changed some time in the future. This situation is particularly dramatic in the case of children and young adults, because of the necessity of valve growth during the patient's life. Our review focuses on the current status of heart valve (HV) therapy and the challenges that must be solved in the development of new approaches based on tissue engineering...
2015: Expert Reviews in Molecular Medicine
https://www.readbyqxmd.com/read/26293756/physiological-growth-remodeling-potential-and-preserved-function-of-a-novel-bioprosthetic-tricuspid-valve-tubular-bioprosthesis-made-of-small-intestinal-submucosa-derived-extracellular-matrix
#13
Farhan Zafar, Robert B Hinton, Ryan A Moore, R Scott Baker, Roosevelt Bryant, Daria A Narmoneva, Michael D Taylor, David L Morales
BACKGROUND: Prosthetic valves currently used in children lack the ability to grow with the patient and often require multiple reoperations. Small intestinal submucosa-derived extracellular matrix (SIS-ECM) has been used successfully as a patch for repair in various tissues, including vessels, valves, and myocardium. OBJECTIVES: This study sought to assess the remodeling potential of a tubular tricuspid valve (TV) bioprosthesis made of SIS-ECM by evaluating its growth, structure, and function in a growing ovine model...
August 25, 2015: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/26238147/long-term-outcomes-and-risk-factors-for-aortic-regurgitation-after-discrete-subvalvular-aortic-stenosis-resection-in-children
#14
Sarah S Pickard, Alon Geva, Kimberlee Gauvreau, Pedro J del Nido, Tal Geva
OBJECTIVES: To characterise long-term outcomes after discrete subaortic stenosis (DSS) resection and to identify risk factors for reoperation and aortic regurgitation (AR) requiring repair or replacement. METHODS: All patients who underwent DSS resection between 1984 and 2009 at our institution with at least 36 months' follow-up were included. Demographic, surgical and echocardiographic data were reviewed. Outcomes were reoperation for recurrent DSS, surgery for AR, death and morbidities, including heart transplant, endocarditis and complete heart block...
October 2015: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/26232985/no-react%C3%A2-injectable-biopulmonic%C3%A2-valves-re-evaluated-discouraging-follow-up-results
#15
Jochen Grohmann, René Höhn, Thilo Fleck, Brigitte Stiller, Elena Neumann, Matthias Sigler, Johannes Kroll, Friedhelm Beyersdorf, Matthias Siepe
OBJECTIVES: The No-React® Injectable BioPulmonic™ valve (BioIntegral) was introduced for minimally invasive off-pump replacement of the pulmonary valve almost 10 years ago. We present our mid- to long-term follow-up results. METHODS: We conducted a retrospective analysis of all 7 patients treated at our institution at the median age of 9 (range 1-24) years. The children underwent cardiac catheterization when worsening strain on the right heart was suspected after examining their medical history and/or observing significant changes on echocardiography...
November 2015: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/26182624/outcome-of-standard-and-bicuspidalized-cryopreserved-homografts-for-primary-right-ventricular-outflow-tract-reconstruction
#16
COMPARATIVE STUDY
Gianluigi Perri, Angelo Polito, Fabrizio Gandolfo, Sonia B Albanese, Adriano Carotti
BACKGROUND AND AIM OF THE STUDY: The study aim was to analyze the safety and longevity of cryopreserved homografts used for primary right ventricular outflow tract reconstruction (RVOTR), and to compare the outcome using either standard or bicuspidalized allografts. METHODS: Between February 2000 and September 2014, a total of 53 patients underwent primary RVOTR using either a standard (n = 40) or a bicuspidalized (n = 13) cryopreserved homograft. The median age at surgery was 15...
January 2015: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/26182613/the-konno-procedure-in-redo-aortic-valve-replacement-after-the-nicks-procedure
#17
Kanji Matsuzakil, Yohei Kudo, Akihiko Ikeda, Taisuke Konishi, Tomoaki Jikuyal, Yuji Hiramatsu
A case is reported of successful surgery using the Konno procedure seven years after the patient had undergone aortic valve replacement (AVR) with the Nicks procedure. A 79-year-old woman with aortic stenosis and a small aortic annulus had undergone previous AVR with a 17-mm mechanical prosthesis and aortic annular enlargement by the Nicks procedure. Redo surgery was performed using a 19-mm bioprosthesis with the Konno procedure, to replace a valve that had become stuck due to pannus formation. As intense adhesion was present around the heart, especially behind the posterior aortic wall where the Nicks procedure had been performed, the Konno procedure provided the advantage of a good field of vision at the aortic annulus...
January 2015: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/26118461/impact-of-ross-operation-on-outcome-in-young-female-adult-patients-wanting-to-have-children
#18
Kazuki Morimoto, Takaya Hoashi, Koji Kagisaki, Jun Yoshimatsu, Isao Shiraishi, Hajime Ichikawa, Junjiro Kobayashi, Takeshi Nakatani, Toshikatsu Yagihara, Soichiro Kitamura, Tomoyuki Fujita
BACKGROUND: The most appropriate valve substitute at aortic valve replacement (AVR) for young female adult patients wanting to have children is unclear. METHODS AND RESULTS: Between 1992 and 2013, 12 consecutive female patients aged >18 (median, 22.5 years; range, 18-34 years) underwent Ross operation (Ross group). Between 1984 and 2013, 9 consecutive female patients aged >18 (median, 30 years; range, 22-39 years) underwent AVR with bioprosthesis (bioprosthesis group)...
2015: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/26059873/aortic-valve-repair-for-insufficiency-in-older-children-offers-unpredictable-durability-that-may-not-be-advantageous-over-a-primary-ross-operation%C3%A2
#19
Travis J Wilder, Christopher A Caldarone, Glen S Van Arsdell, Eric Pham-Hung, Michael Gritti, Mohammed Al Jughiman, Edward J Hickey
OBJECTIVES: To evaluate the durability of aortic valve (AoV) repair relative to other strategies for children with significant aortic insufficiency (AI). METHODS: From 2001 to 2012, 90 children with greater than or equal to moderate AI underwent surgery. Resulting procedures were classified according to final operative outcome: AoV repair (repair; n = 46, 51%), Ross procedure (Ross; n = 21, 23%) or replacement with mechanical or tissue prosthesis [aortic valve replacement (AVR); n = 23, 26%]...
March 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/26048261/anticoagulant-management-of-pregnant-women-with-mechanical-heart-valve-replacement-during-perioperative-period
#20
Ce Bian, Xiaorong Qi, Li Li, Jitong Zhao, Xinghui Liu
OBJECTIVE: To investigate the morbidity of complications and pregnancy outcomes in women with mechanical heart valve replacement who received low-dose oral anticoagulation treatment with warfarin throughout the pregnancy, compare the prognosis and complications of patients who were treated with single oral warfarin treatment or the "bridging" therapy treatment, investigate the influence of using vitamin K1 before emergency cesarean section delivery on postoperative warfarin anticoagulant effect and to explore an appropriate anticoagulant regimen during perioperative period for pregnant women with mechanical heart valve replacement...
January 2016: Archives of Gynecology and Obstetrics
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