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Valve prosthesis pediatric

Fernand Missohou
PURPOSE: Bowel is often the dose-limiting organ in curative pelvic irradiation because of radiation enteritis when dose exceeds 40 to 45 Gy. To limit radiation enteritis, a silicone tissue-expander prothesis (STEP) connected to a subcutaneous self-sealing valve was prospectively used in children undergoing pelvic or abdominal radiation therapy. This study reports the 15-year long-term outcomes of this prospective series. METHODS AND MATERIALS: Between 1987 and 2008, 29 children from 3 Paris institutions received pelvic radiation therapy after surgical placement of a STEP in the pelvis...
December 14, 2017: Practical Radiation Oncology
Ireneusz Haponiuk, Maciej Chojnicki, Radosław Jaworski, Mariusz Steffens, Konrad Paczkowski, Aneta Szofer-Sendrowska, Marta Paśko-Majewska, Katarzyna Gierat-Haponiuk, Anna Romanowicz, Wiktor Szymanowicz
BACKGROUND AND AIM: Acute endocarditis (AE) is still rare disease in the paediatric population; nevertheless, the children suffering from AE usually need heart valve repair or replacement in emergency settings. METHODS: We present a case of emergency mitral valve replacement with the use of Melody balloon expandable stented bioprosthesis in a two-year-old patient with AE and subsequent mitral (bicuspid) valve incompetence after aggressive infective destruction with the symptoms of critical multi-organ failure...
2017: Kardiologia Polska
Rachael W Quinn, Arthur A Bert, Gabriel L Converse, Eric E Buse, Stephen L Hilbert, William B Drake, Richard A Hopkins
BACKGROUND: Cardiac allometric organ growth after pediatric valve replacement can lead to patient-prosthesis size mismatch and valve re-replacement, which could be mitigated with allogeneic decellularized pulmonary valves treated with collagen conditioning solutions to enhance biological and mechanical performance, termed "bioengineered valves." In this study, we evaluated functional, dimensional, and biological responses of these bioengineered valves compared with traditional cryopreserved valves implanted in lambs during rapid somatic growth...
October 2016: Journal of Thoracic and Cardiovascular Surgery
Nels D Carroll, Kevin M Beers, Elaine M Maldonado, John H Calhoon, S Adil Husain
Reparative procedures are not always feasible in congenitally abnormal mitral valves. Mechanical prosthesis has been accepted as the choice for valve replacement in the pediatric population. This report describes a case of congenital mitral valve disease requiring mitral valve replacement. The infant's mitral valve annulus was not amenable to placement of the smallest available mechanical prosthesis. The approach used here for annular and subvalvular enlargement facilitated implantation of a larger prosthesis for congenital mitral valve replacement...
September 2016: Annals of Thoracic Surgery
John W Brown, Parth M Patel, Jiuann-Huey Ivy Lin, Asma S Habib, Mark D Rodefeld, Mark W Turrentine
BACKGROUND: The Ross aortic valve replacement (AVR) has been the AVR of choice for children at our center since 1993. Absence or inadequate quality of the pulmonary valve or, less commonly, family or surgeon preference caused us to select an alternative AVR prosthesis for some children. This review compares the outcomes of 42 children who received a non-Ross AVR with 115 children undergoing Ross root replacement at our institution during the most recent 22 years. METHODS: A retrospective chart review of the 42 pediatric non-Ross AVRs was compared with 115 Ross AVRs...
May 2016: Annals of Thoracic Surgery
Erin G Roberts, Luis Quinonez, Breanna Piekarski, Christopher W Baird, Sitaram M Emani
PURPOSE: Options for pediatric valve replacement are limited by inability to adapt to child growth. An expandable valve design is presented in which human cryopreserved venous valved conduits are constructed within a bare-metal stent scaffold. We demonstrate functionality in vitro and acute competence in vivo. DESCRIPTION: A cryopreserved femoral venous valved conduit was compressed within a bare-metal stent scaffold and sutured at the proximal and distal ends. In vitro testing was performed at low and high pressure after sequential balloon expansion...
December 2015: Annals of Thoracic Surgery
Michael L O'Byrne, Matthew J Gillespie, Russell T Shinohara, Yoav Dori, Jonathan J Rome, Andrew C Glatz
Outcomes for transcatheter pulmonary valve replacement (TC-PVR) and operative pulmonary valve replacement (S-PVR) are excellent. Thus, their respective cost is a relevant clinical outcome. We performed a retrospective cohort study of children and adults who underwent PVR at age ≥ 8 years from January 1, 2011, to December 31, 2013, at 35 centers contributing data to the Pediatric Health Information Systems database to address this question. A propensity score-adjusted multivariable analysis was performed to adjust for known confounders...
January 1, 2016: American Journal of Cardiology
Jonathan R G Etnel, Lisa C Elmont, Ebru Ertekin, M Mostafa Mokhles, Helena J Heuvelman, Jolien W Roos-Hesselink, Peter L de Jong, Willem A Helbing, Ad J J C Bogers, Johanna J M Takkenberg
OBJECTIVE: Despite an increasing interest in pediatric aortic valve repair, aortic valve replacement in children may be unavoidable. The evidence on outcome after pediatric aortic valve replacement is limited and usually reported in small case series. This systematic review and meta-analysis aims to provide an overview of reported outcome of pediatric patients after aortic valve replacement. METHODS: A systematic literature search for publications reporting outcome after pediatric aortic valve replacement published between January 1990 and May 2015 was conducted...
January 2016: Journal of Thoracic and Cardiovascular Surgery
Domenico Mazzitelli, Christian Nöbauer, J Scott Rankin, Manfred Vogt, Rüdiger Lange, Christian Schreiber
Three clinical cases of severe pediatric aortic valve defects undergoing complete aortic valve cusp replacement using tissue-engineered bovine pericardium are reported. All patients achieved excellent early results, and are being followed without complications.
November 2015: Annals of Thoracic Surgery
Eugen Sandica, Ute Blanz, Lotfi Ben Mime, Ursula Schultz-Kaizler, Deniz Kececioglu, Nikolaus Haas, Guenther Kirchner, Edzard zu Knyphausen, Volker Lauenroth, Michiel Morshuis
This retrospective study reviews our results regarding the long-term support in pediatric patients using two ventricular assist systems between January 2008 and April 2014. We implanted the Berlin Heart EXCOR in 29 patients (median age 3.4 years [interquartile range (IQR) 0.2-16.5], median weight 13 kg [IQR 4.2-67.2]). Twenty-two patients (75.8%) received a left ventricular assist device. Three patients (10.3%) had single-ventricle physiology. One patient (3.4%) had mechanical mitral valve prosthesis. The HeartWare System was implanted in nine patients...
March 2016: Artificial Organs
Yasutaka Hirata
The acute mitral regurgitation of the infants are believed to be very rare until recently. However, there have been increasing number of reports of acute massive mitral regurgitation attributable to rupture of the chordae tendaniae escecially in Japan. If undiagnosed or the optimal treatment including surgery is delayed, it may cause cardiogenic shock and death in infants. Thus pediatricians, pediatric cardiologists and pediatric caridiac surgeons should consider this diagnosis when previously healthy infant suddenly develop cardiorespiratory collapse...
July 2015: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Bhawna Gupta, Ali Dodge-Khatami, Charles D Fraser, John H Calhoon, Makram R Ebeid, Mary B Taylor, Jorge D Salazar
BACKGROUND: Management of systemic semilunar valve disease in growing, young patients is challenging. When replacement is necessary, use of a pulmonary autograft is sometimes not possible for anatomic, pathologic, or technical reasons or due to parental or patient preference. We employed a stentless, porcine, full-root bioprosthesis in this setting and report our outcomes. METHODS: Over 9 years (2005 to 2013), 24 patients of mean age 13.1 years (range, 3 months to 20...
August 2015: Annals of Thoracic Surgery
Andrew Chen, Fei Yu, Simon K Law, JoAnn A Giaconi, Anne L Coleman, Joseph Caprioli
IMPORTANCE: Relatively little data exist about the long-term outcomes of an initial glaucoma drainage device (GDD) and subsequent GDDs implanted in pediatric patients with glaucoma. OBJECTIVE: To determine the long-term outcomes of the first and second GDDs and risk factors in pediatric glaucoma. DESIGN, SETTING, AND PARTICIPANTS: Retrospective review of 119 eyes of 89 patients younger than 18 years with glaucoma who underwent valved GDD implantation from March 1999 to April 2012 at the Stein Eye Institute, University of California, Los Angeles...
September 2015: JAMA Ophthalmology
Adriana Luk, Vivek Rao, Robert J Cusimano, Tirone E David, Jagdish Butany
Decellularized extracellular matrix from porcine intestinal submucosa is available as an approved material for the repair of tissues including cardiac structures. Although pathologic findings of explanted CorMatrix (CorMatrix Cardiovascular, Inc, Roswell, GA) used for valvular repair have been reported in the pediatric population, there is a paucity of data in the adult population. Herein, we report the histologic changes in explanted CorMatrix from 2 adults at 10 and 18 months post-implant.
June 2015: Annals of Thoracic Surgery
Jay M Reimer, Zeeshan H Syedain, Bee H T Haynie, Robert T Tranquillo
Pediatric patients account for a small portion of the heart valve replacements performed, but a pediatric pulmonary valve replacement with growth potential remains an unmet clinical need. Herein we report the first tubular heart valve made from two decellularized, engineered tissue tubes attached with absorbable sutures, which can meet this need, in principle. Engineered tissue tubes were fabricated by allowing ovine dermal fibroblasts to replace a sacrificial fibrin gel with an aligned, cell-produced collagenous matrix, which was subsequently decellularized...
September 2015: Biomaterials
John P Cheatham, William E Hellenbrand, Evan M Zahn, Thomas K Jones, Darren P Berman, Julie A Vincent, Doff B McElhinney
BACKGROUND: Studies of transcatheter pulmonary valve (TPV) replacement with the Melody valve have demonstrated good short-term outcomes, but there are no published long-term follow-up data. METHODS AND RESULTS: The US Investigational Device Exemption trial prospectively enrolled 171 pediatric and adult patients (median age, 19 years) with right ventricular outflow tract conduit obstruction or regurgitation. The 148 patients who received and were discharged with a TPV were followed up annually according to a standardized protocol...
June 2, 2015: Circulation
Christopher J Petit
No abstract text is available yet for this article.
June 2, 2015: Circulation
Ben Dunne, Alex Xiao, Edward Litton, David Andrews
It remains unclear as to whether mechanical valves have a role in pulmonary valve replacement. A systematic review and meta-analysis was performed to answer this question. Nineteen observational studies, including 299 pediatric and adult patients with a mean follow-up of 73 months, were analyzed. Nonstructural valve deterioration and valve thrombosis occurred in 1.5% and 2.2% of patients, respectively. Surgical reintervention was required in 0.9% of cases and thrombolysis was required in 0.5%. Mechanical valves in the pulmonary position are associated with a low incidence of valve deterioration and thrombosis, as well as freedom from reoperation and thrombolysis...
2015: Annals of Thoracic Surgery
Eung Re Kim, Woong-Han Kim, Eun Seok Choi, Sungkyu Cho, Woo Sung Jang, Yong Jin Kim
BACKGROUND: Mitral regurgitation is one of the leading causes of cardiovascular morbidity in pediatric patients with Marfan syndrome. The purpose of this study was to contribute to determining the appropriate surgical strategy for these patients. METHODS: From January 1992 to May 2013, six patients with Marfan syndrome underwent surgery for mitral regurgitation in infancy or early childhood. RESULTS: The median age at the time of surgery was 47 months (range, 3 to 140 months) and the median follow-up period was 3...
February 2015: Korean Journal of Thoracic and Cardiovascular Surgery
Sharon Borik, Andrew Crean, Eric Horlick, Mark Osten, Kyong-Jin Lee, Rajiv Chaturvedi, Mark K Friedberg, Brian W McCrindle, Cedric Manlhiot, Lee Benson
BACKGROUND: Percutaneous pulmonary valve implantation (PPVI) is a safe, less invasive alternative to surgical valve replacement for the congenital heart disease patient with right ventricular (RV) outflow tract dysfunction. The aim of this study was to determine whether reverse RV remodeling after PPVI was persistent in the longer term and whether timing of PPVI influenced outcomes. METHODS AND RESULTS: Consecutive patients from the pediatric and adult congenital heart disease programs were enrolled...
February 2015: Circulation. Cardiovascular Interventions
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