keyword
MENU ▼
Read by QxMD icon Read
search

PCV

keyword
https://www.readbyqxmd.com/read/29781740/predicting-the-impact-of-pneumococcal-conjugate-vaccine-programme-options-in-vietnam
#1
Olivier Le Polain de Waroux, W John Edmunds, Kensuke Takahashi, Koya Ariyoshi, E Kim Mulholland, David Goldblatt, Yoon Hong Choi, Dang Duc Anh, Lay Myint Yoshida, Stefan Flasche
Although catch-up campaigns (CCs) at the introduction of pneumococcal conjugate vaccines (PCVs) may accelerate their impact, supply constraints may limit their benefit if the need for additional PCV doses results in introduction delay. We studied the impact of PCV13 introduction with and without CC in Nha Trang, Vietnam - a country that has not yet introduced PCV - through a dynamic transmission model. We modelled the impact on carriage and invasive pneumococcal disease (IPD) of routine vaccination (RV) only and that of RV with CCs targeting <1y olds (CC1), <2y olds (CC2) and <5y olds (CC5)...
May 21, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29776921/determining-the-pneumococcal-conjugate-vaccine-coverage-required-for-indirect-protection-against-vaccine-type-pneumococcal-carriage-in-low-and-middle-income-countries-a-protocol-for-a-prospective-observational-study
#2
Jocelyn Chan, Cattram D Nguyen, Jana Y R Lai, Eileen M Dunne, Ross Andrews, Christopher C Blyth, Siddhartha Datta, Kim Fox, Rebecca Ford, Jason Hinds, Sophie La Vincente, Deborah Lehmann, Ruth Lim, Tuya Mungun, Paul N Newton, Rattanaphone Phetsouvanh, Willam S Pomat, Anonh Xeuatvongsa, Claire von Mollendorf, David A B Dance, Catherine Satzke, Kim Muholland, Fiona M Russell
INTRODUCTION: Pneumococcal conjugate vaccines (PCVs) prevent disease through both direct protection of vaccinated individuals and indirect protection of unvaccinated individuals by reducing nasopharyngeal (NP) carriage and transmission of vaccine-type (VT) pneumococci. While the indirect effects of PCV vaccination are well described, the PCV coverage required to achieve the indirect effects is unknown. We will investigate the relationship between PCV coverage and VT carriage among undervaccinated children using hospital-based NP pneumococcal carriage surveillance at three sites in Asia and the Pacific...
May 18, 2018: BMJ Open
https://www.readbyqxmd.com/read/29774989/first-report-of-wild-boar-susceptibility-to-porcine-circovirus-type-3-high-prevalence-in-the-colli-euganei-regional-park-italy-in-the-absence-of-clinical-signs
#3
Giovanni Franzo, Claudia Maria Tucciarone, Michele Drigo, Mattia Cecchinato, Marco Martini, Alessandra Mondin, Maria Luisa Menandro
The genus Circovirus includes one of the most relevant infectious agents affecting domestic pigs, Porcine circovirus type 2 (PCV-2). The wild boar susceptibility to this pathogen has also been demonstrated although the actual epidemiological role of wild populations is still debated. In recent times, a new circovirus, Porcine circovirus type 3 (PCV-3), has been discovered and reported in the presence of several clinical conditions. However, no information is currently available about PCV-3 circulation and prevalence in wild boar...
May 18, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29768458/burden-of-bacterial-meningitis-in-india-preliminary-data-from-a-hospital-based-sentinel-surveillance-network
#4
Yuvaraj Jayaraman, Balaji Veeraraghavan, Girish Kumar Chethrapilly Purushothaman, Bharathy Sukumar, Boopathi Kangusamy, Ambujam Nair Kapoor, Nivedita Gupta, Sanjay Madhav Mehendale
BACKGROUND: Worldwide, acute bacterial meningitis is a major cause of high morbidity and mortality among under five children, particularly in settings where vaccination for H. influenzae type b, S. pneumoniae and N. meningitidis is yet to be introduced in the national immunization programs. Estimation of disease burden of bacterial meningitis associated with these pathogens can guide the policy makers to consider inclusion of these newer vaccines in the immunization programs. A network of hospital based sentinel surveillance was established to generate baseline data on the burden of bacterial meningitis among children aged less than 5 years in India and to provide a platform for impact assessment following introduction of the Pentavalent and Pneumococcal Conjugate Vaccines (PCV)...
2018: PloS One
https://www.readbyqxmd.com/read/29768266/subfoveal-choroidal-thickness-in-eyes-with-neovascular-age-related-macular-degeneration-treated-with-anti-vascular-endothelial-growth-factor-agents
#5
Tereza Cristina Moreira Kanadani, Carlos Eduardo Veloso, Márcio B Nehemy
PURPOSE: We aimed to assess the subfoveal choroidal thickness (SFChT) and the effect of treatment with anti-vascular endothelial growth factor (anti-VEGF) agents on the SFChT in age-related macular degeneration (AMD) subtypes. METHODS: We enrolled 128 eyes of 107 patients with neovascular AMD (60 women; 47 men; mean age, 73.6 ± 8.9 years), and prospectively evaluated the best-corrected visual acuity (BCVA) and SFChT at baseline and at 3, 6, and 12 months after treatment with anti-VEGF agents...
May 16, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29765775/potential-impact-of-introducing-the-pneumococcal-conjugate-vaccine-into-national-immunisation-programmes-an-economic-epidemiological-analysis-using-data-from-india
#6
Itamar Megiddo, Eili Klein, Ramanan Laxminarayan
Pneumococcal pneumonia causes an estimated 105 000 child deaths in India annually. The planned introduction of the serotype-based pneumococcal conjugate vaccine (PCV) is expected to avert child deaths, but the high cost of PCV relative to current vaccines provided under the Universal Immunization Programme has been a concern. Cost-effectiveness studies from high-income countries are not readily comparable because of differences in the distribution of prevalent serotypes, population and health systems. We extended IndiaSim, our agent-based simulation model representative of the Indian population and health system, to model the dynamics of Streptococcus pneumoniae ...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29764550/-predictive-value-of-central-venous-to-arterial-carbon-dioxide-partial-pressure-difference-for-fluid-responsiveness-in-septic-shock-patients-a-prospective-clinical-study
#7
Guangyun Liu, Huibin Huang, Hanyu Qin, Bin Du
OBJECTIVE: To evaluate the accuracy of central venous-to-arterial carbon dioxide partial pressure difference (Pcv-aCO2 ) before and after rapid rehydration test (fluid challenge) in predicting the fluid responsiveness in patients with septic shock. METHODS: A prospective observation was conducted. Forty septic shock patients admitted to medical intensive care unit (ICU) of Peking Union Medical College Hospital from October 2015 to June 2017 were enrolled. All of the patients received fluid challenge in the presence of invasive hemodynamic monitoring...
May 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29758977/evaluation-of-plantar-pressures-in-people-with-hallux-valgus-using-principal-component-analysis
#8
Kanako Nakajima, Yoshiyuki Kobayashi, Mitsunori Tada, Masaaki Mochimaru
BACKGROUND: Foot deformities are serious problems in the elderly as they increase the risk of falling. OBJECTIVE: This study aimed to examine the relationship between foot plantar pressure during gait and hallux valgus (HV). METHODS: Foot-pressure data were recorded using an F-scan II system. We analyzed the entire waveform of plantar pressure during gait from 37 healthy adults using principle component analysis (PCA), conducted using a 370 × 357 matrix of time-normalized plantar data of 7 areas during gait (5 gait trials × 2 (both feet) of 37 participants × 51 data points × 7 plantar areas)...
April 29, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29757851/effect-of-posterior-corneal-vesicles-on-corneal-endothelial-cell-density-and-anisometropic-amblyopia
#9
Atsushi Noguchi, Naoki Okumura, Chie Sotozono, Shigeru Kinoshita
PURPOSE: To evaluate the effect of corneal vesicles in patients with posterior corneal vesicles (PCV) on corneal endothelial cell (CEC) density and the acquisition of amblyopia. METHODS: In this retrospective study of patients with PCV (18 eyes of 14 patients), CEC density was examined by noncontact specular microscopy during each follow-up examination. Best-corrected visual acuity and the objective refractive error were also examined. RESULTS: Of the 14 total patients, 10 were diagnosed with PCV and 4 were diagnosed with bilateral suspected PCV or posterior polymorphous corneal dystrophy (PPCD), and in all patients, no ocular abnormality other than corneal vesicles was observed...
May 1, 2018: Cornea
https://www.readbyqxmd.com/read/29755190/venous-blood-gases-plasma-biochemistry-and-hematology-of-wild-caught-common-chameleons-chamaeleo-chamaeleon
#10
David Eshar, Melanie Ammersbach, Boaz Shacham, Gad Katzir, Hugues Beaufrère
The purpose of this study was to determine a wide range of selected hematologic, venous blood gases, and plasma biochemistry analytes in common chameleons (Chamaeleo chamaeleon) . Blood samples were collected from the ventral tail vein of 41 common chameleons to determine reference intervals for 30 different blood analytes. The calcium-to-phosphorus ratio, packed cell volume (PCV), refractometric total solids (TS), blood cell counts, and differentials were also determined. The microscopic evaluation of blood smears revealed inclusion bodies in monocytes in 7 of the samples...
April 2018: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/29753852/color-fundus-photography-optical-coherence-tomography-and-fluorescein-angiography-in-diagnosing-polypoidal-choroidal-vasculopathy
#11
Voraporn Chaikitmongkol, Preeyanuch Khunsongkiet, Direk Patikulsila, Mansing Ratanasukon, Nawat Watanachai, Chaisiri Jumroendararasame, Catherine B Mayerle, Ian C Han, Connie J Chen, Pawara Winaikosol, Chutikarn Dejkriengkraikul, Janejit Choovuthayakorn, Paradee Kunavisarut, Neil M Bressler
PURPOSE: To determine sensitivity and specificity of polypoidal choroidal vasculopathy (PCV) diagnosis using color fundus photography (CFP), optical coherence tomography (OCT) and fundus fluorescein angiography (FFA) without indocyanine-green angiography (ICGA). DESIGN: Validity analysis. METHODS: Treatment-naïve eyes with serous/serosanguinous maculopathy undergoing CFP, OCT, FFA and ICGA imaging before treatment at a university-hospital in Thailand (January 2013 to June 2015) were identified...
May 10, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29752840/hematological-and-immunological-reference-intervals-for-adult-population-in-the-state-of-amhara-ethiopia
#12
Bamlaku Enawgaw, Wubet Birhan, Molla Abebe, Betelihem Terefe, Habtamu Wondifraw Baynes, Tekalign Deressa, Mulugeta Melku
OBJECTIVE: Reference intervals (RIs) currently being used in Ethiopia are derived from western populations. Thus, this study aimed to establish locally derived hematological and immunological RIs. METHOD: The study was conducted in Amhara State, Ethiopia with a total of 967 (55.2% males) participants. 56.9% of males and 43.1% of females were eligible for hematological and immunological RI determination. A non-parametric test was used for the determination of upper (97...
May 12, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29750768/dynamics-of-severe-and-non-severe-invasive-pneumococcal-disease-in-young-children-in-israel-following-pcv7-pcv13-introduction
#13
Daniel Glikman, Ron Dagan, Galia Barkai, Diana Averbuch, Alex Guri, Noga Givon-Lavi, Shalom Ben-Shimol
BACKGROUND: The introduction of the pneumococcal conjugated vaccines (PCVs) resulted in a substantial reduction of invasive pneumococcal disease (IPD) rates. However, impact on non-severe IPD (mostly occult bacteremia) has not yet been fully elucidated.We assessed severe and non-severe IPD (SIPD and NSIPD, respectively) rate dynamics in children <5 years in Israel before and after PCV7/PCV13 implementation. METHODS: A prospective, population-based, nationwide surveillance...
May 10, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29746511/choroidal-structure-as-a-biomarker-for-visual-acuity-in-intravitreal-aflibercept-therapy-for-polypoidal-choroidal-vasculopathy
#14
Shotaro Asano, Keiko Azuma, Kimiko Shimizu, Risako Yamamoto, Jinhee Lee, Hiroshi Murata, Tatsuya Inoue, Ryo Asaoka, Ryo Obata
PURPOSE: To investigate the relationship between choroidal structure and visual acuity after intravitreal aflibercept therapy for polypoidal choroidal vasculopathy (PCV). METHODS: We conducted a retrospective, single-centre and observational study including 18 eyes of 18 patients with PCV (73.8 ± 10.2 years of age) who were treated with three monthly intravitreal aflibercept injections followed by additional treatments in a treat-and-extend protocol. The cross-sectional images of the macula were obtained with enhanced depth imaging optical coherence tomography at baseline, at 3 months, and at 12 months...
2018: PloS One
https://www.readbyqxmd.com/read/29742644/invasive-pneumococcal-disease-in-neonates-prior-to-pneumococcal-conjugate-vaccine-use-in-south-africa-2003-2008
#15
Krishnee Moodley, Yacoob Mahomed Coovadia, Cheryl Cohen, Susan Meiring, Sarona M Lengand, Linda De Gouveia, Claire von Mollendorf, Penny Crowther-Gibson, Vanessa Quan, Brian Eley, Gary Reubenson, Trusha Nana, Anne von Gottberg
BACKGROUND: Neonatal invasive pneumococcal disease (IPD) in developing countries is poorly described. We provide a baseline description of neonatal IPD in South Africa, prior to implementation of the seven-valent pneumococcal conjugate vaccine (PCV7) in 2009. METHODS: Data from children (age ≤ 2 years) with IPD (pneumococcus identified from a normally sterile specimen) from January 2003 - December 2008 were extracted from a national laboratory-based surveillance database...
May 4, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29736610/occult-bacteremia-etiology-following-the-introduction-of-13-valent-pneumococcal-conjugate-vaccine-a-multicenter-study-in-spain
#16
Susanna Hernández-Bou
Little is known about occult bacteremia (OB) in Spain following the introduction of the 13-valent pneumococcal conjugated vaccine (PCV13). Our aim was to describe the microbiologic characteristics and management of OB among children aged 3-36 months in Spain in the era of PCV13. Data were obtained from a multicenter registry of positive blood cultures collected at 22 Spanish emergency departments (ED). Positive blood cultures performed on patients aged 3-36 months from 2011 to 2015 were retrospectively identified...
May 7, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29735523/a-capsular-polysaccharide-specific-antibody-alters-streptococcus-pneumoniae-gene-expression-during-nasopharyngeal-colonization-of-mice
#17
Christopher R Doyle, Jee-Young Moon, Johanna P Daily, Tao Wang, Liise-Anne Pirofski
Pneumococcal conjugate vaccines (PCV) elicit opsonophagocytic (opsonic) antibodies to pneumococcal capsular polysaccharides (PPS) and reduce nasopharyngeal (NP) colonization by vaccine-included Streptococcus pneumoniae serotypes. However, non-opsonic antibodies may also be important for protection against pneumococcal disease. For example, 1E2, a mouse IgG1 monoclonal antibody (mAb) to the serotype 3 (ST3) PPS reduced ST3 NP colonization in mice and altered ST3 gene expression in vitro Here, we determined whether 1E2 affects ST3 gene expression in vivo during colonization of mice by performing RNA-seq on NP lavage fluid from ST3-infected mice treated with 1E2, a control mAb, or PBS...
May 7, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29716855/effect-of-black-seed-oil-supplementation-on-selected-immunological-hematological-and-iron-status-parameters-in-ribavirin-treated-female-albino-rats
#18
H A Abd-Elmonem
Ribavirin has been found to enhance the anti HCV potential of pegylated interferon and sovaldi. However its use was associated with impact on the hemopoietic system and iron status. The hemopoietic toxicity, sometimes forced patients to reduce the dosage or to discontinue treatment in rare occasions. The main purpose of the present study was to assess the potential of black seed oil, a known potent antioxidant, to ameliorate the negative impact of ribavirin on hematological indices, iron status and natural immunity in rats...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29709448/evaluation-of-the-association-of-pneumococcal-conjugate-vaccine-immunization-and-density-of-nasopharyngeal-bacterial-colonization-using-a-multiplex-quantitative-polymerase-chain-reaction-assay
#19
Courtney P Olwagen, Peter V Adrian, Marta C Nunes, Shabir A Madhi
BACKGROUND: Nasopharyngeal bacterial colonization is a pre-requisite for developing bacterial mucosal and invasive disease. Pneumococcal conjugate vaccine (PCV) immunization of children reduces their risk of colonization by vaccine-serotypes, which could affect the biome of the nasopharynx in relation to colonization by other bacteria. This study evaluated the association of PCV immunization on the prevalence density of nasopharyngeal colonization by common, potentially pathogenic bacteria...
April 27, 2018: Vaccine
https://www.readbyqxmd.com/read/29708864/first-time-detection-of-porcine-reproductive-and-respiratory-syndrome-virus-and-porcine-circovirus-2-in-an-albanian-farrow-to-finish-herd
#20
Vasileios G Papatsiros, Serafeim C Chaintoutis, Dimitra Psalla, Georgios G Maragkakis, Georgios Christodoulopoulos, Chrysostomos I Dovas
The purpose of this case report is to describe for the first time concurrent porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus 2 (PCV-2) infections in a commercial farrow-to-finish pig farm in Albania, as well as the phylogenetical analysis of isolated PRRSV strain. The present study reports on a farrow-to-finish commercial pig farm, located in South Albania. In a percentage of about 40% of weaners in each batch (60-70 piglets per batch), clinical signs, including fever, severe respiratory signs, wasting, jaundice, rough hairy coat, palpable inguinal lymphadenopathy, and high mortality rate, were performed...
April 30, 2018: Viral Immunology
keyword
keyword
118839
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"