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https://www.readbyqxmd.com/read/28099573/hematological-and-morphometric-differences-of-blood-cells-from-rheas-rhea-americana-struthioniformes-rheidae-on-two-conservation-farms
#1
S S M Gallo, N B Ederli, F C R Oliveira
Today, blood tests are an indispensable tool in avian medicine. This study aimed to describe and compare hematological and morphometric data of erythrocytes, leukocytes and thrombocytes of rhea, Rhea americana. To do so, 58 rheas of both sexes on two farms, one in Cachoeiro do Itapemirim, Espírito Santo (ES), and the other in São Carlos, São Paulo (SP), were selected. Blood samples were taken and their RBC counts, PCV and Hb levels were determined and used in hematimetric index calculations. The total and differentiated leukocyte counts and the TPP and fibrinogen serum levels were also obtained...
January 12, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28091356/resistance-to-gastrointestinal-parasite-infection-in-djallonk%C3%A3-sheep
#2
A Traoré, D R Notter, A Soudre, A Kaboré, I Álvarez, I Fernández, M Sanou, M Shamshuddin, K Periasamy, H H Tamboura, F Goyache
Gastrointestinal parasitism places serious constraints on small ruminant production. The situation has been exacerbated by development of drug resistance in many parasite populations, leading to interest in identification of animals with genetically mediated resistance or tolerance to nematode infections. This study assessed the response to natural infection with gastrointestinal nematodes (GIN) in Djallonké sheep during the rainy season in the Sudan-Guinea Savannah region of Burkina Faso. Haemonchus contortus is the most prevalent GIN at this site and time...
January 16, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28087148/immunogenicity-differences-of-a-15-valent-pneumococcal-polysaccharide-conjugate-vaccine-pcv15-based-on-vaccine-dose-route-of-immunization-and-mouse-strain
#3
REVIEW
Ivette Caro-Aguilar, Lani Indrawati, Robin M Kaufhold, Christine Gaunt, Yuhua Zhang, Denise K Nawrocki, Cecilia Giovarelli, Michael A Winters, William J Smith, Jon Heinrichs, Julie M Skinner
Pneumococcal disease continues to be a medical need even with very effective vaccines on the market. Globally, there are extensive research efforts to improve serotype coverage with novel vaccines; therefore, conducting preclinical studies in different animal models becomes essential. The work presented herein focuses on evaluating a 15-valent pneumococcal conjugate vaccine (PCV15) in mice. Initially we evaluated several doses of PCV15 in Balb/c mice. The optimal vaccine dose was determined to be 0.4μg per pneumococcal polysaccharide (PS) (0...
January 10, 2017: Vaccine
https://www.readbyqxmd.com/read/28087146/pcv13-vaccinated-children-still-carrying-pcv13-additional-serotypes-show-similar-carriage-density-to-a-control-group-of-pcv7-vaccinated-children
#4
Ron Dagan, Christine Juergens, James Trammel, Scott Patterson, David Greenberg, Noga Givon-Lavi, Nurith Porat, William C Gruber, Daniel A Scott
BACKGROUND: In addition to reducing vaccine-type nasopharyngeal carriage rates, pneumococcal conjugate vaccines (PCVs) may decrease carriage density in vaccinated individuals still carrying vaccine serotypes. However, reduction of carriage density has not been systematically studied. This study compared the effect of PCV13 versus PCV7 on carriage density of the serotypes in PCV13 that are not included in PCV7. METHODS: This randomized, double-blind study was conducted in southern Israel and included Jewish and Bedouin subjects...
January 10, 2017: Vaccine
https://www.readbyqxmd.com/read/28070670/the-impact-of-pneumococcal-conjugate-vaccine-on-community-acquired-pneumonia-hospitalizations-in-children-with-comorbidity
#5
Ellinor Sterky, Rutger Bennet, Ann Lindstrand, Margareta Eriksson, Anna Nilsson
: The burden of community-acquired pneumonia (CAP) in high-income countries is still significant. The introduction of pneumococcal conjugate vaccines (PCV) has reduced the overall need for hospitalization for CAP. However, it is not clear whether children with underlying disease also have benefitted from the PCV immunization programme. Children 0 to <5 years of age hospitalized with CAP and discharged with an ICD-10 code of J13-J18.9 between November 1, 2005, and April 30, 2007 (pre-vaccination period), and November 1, 2010, and April 30, 2012 (post-vaccination period), were eligible for this study...
January 9, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28066834/the-role-of-ventilation-mode-using-a-laryngeal-mask-airway-during-gynecological-laparoscopy-on-lung-mechanics-hemodynamic-response-and-blood-gas-analysis
#6
Mohammad Hossein Jarahzadeh, Iman Halvaei, Farshid Rahimi-Bashar, Shekoufeh Behdad, Rouhollah Abbasizadeh Nasrabady, Elahe Yasaei
BACKGROUND: There are two methods for ventilation in gynecological laparoscopy: volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV). OBJECTIVE: To compare the lung mechanics, hemodynamic response and arterial blood gas analysis and gas exchange of two modes of VCV and PCV using laryngeal mask airway (LMA) at different time intervals. MATERIALS AND METHODS: Sixty infertile women referred for diagnostic laparoscopy, based on ventilation mode, were randomly divided into two groups of VCV (tidal volume: 10 ml/kg) and PCV...
December 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28060392/intravitreal-aflibercept-for-neovascular-polypoidal-choroidal-vasculopathy-in-a-predominantly-non-asian-population-rival-results
#7
Amina Farooq, Heather Frazier, William B Marcus, Chelsea Fechter, Harinderjit Singh, Dennis M Marcus
BACKGROUND AND OBJECTIVE: To evaluate safety and efficacy of intravitreal aflibercept (Eylea; Regeneron, Tarrytown, NY) injection (IAI) for the treatment of neovascular polypoidal choroidal vasculopathy (PCV) in a predominantly non-Asian population. PATIENTS AND METHODS: This was an open-label, prospective, unmasked, nonrandomized clinical trial. Twenty eyes with neovascular PCV received monthly 2.0 mg IAI for 3 months followed by mandatory IAI every 2 months for 12 months...
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28060148/short-term-safety-of-2-mg-intravitreal-ziv-aflibercept
#8
Jay Chhablani, Chintan Jethalal Dedhia, Hari K Peguda, Michael Stewart
PURPOSE: To evaluate the safety of single intravitreal 2 mg ziv-aflibercept (0.08 mL) injections for the treatment of choroidal neovascular membranes (CNVM). METHODS: Eyes with choroidal neovascular membranes because of several conditions each received single intravitreal injections of 2 mg ziv-aflibercept (0.08 mL). Comprehensive ophthalmic examinations and detailed systemic evaluations were performed at baseline and Days 1, 7, and 30 after injections. Standard electroretinography was performed at baseline and Day 30...
January 2, 2017: Retina
https://www.readbyqxmd.com/read/28059611/molecular-characterization-of-pneumococcal-surface-protein-k-a-potential-pneumococcal-vaccine-antigen
#9
A-Yeung Jang, Ho Seong Seo, Shunmei Lim, Gook-Hyun Chung, Han Wool Kim, Sangyong Lim, Lei Zhao, In-Ho Park, Jae Hyang Lim, Kyung-Hyo Kim
The pneumococcal capsule is indispensable for pathogenesis in systemic infections; however, many pneumococcal diseases, including conjunctivitis, otitis media, and some systemic infections in immunocompromised patients, are caused by nonencapsulated Streptococcus pneumoniae (NESp). Null capsule clade 1 (NCC1), found in group 2 NESp, expresses pneumococcal surface protein K (PspK) and is becoming prevalent among pneumococcal organisms owing to the widespread use of pneumococcal conjugate vaccines. Despite its clinical importance, the molecular mechanisms underlying the prevalence of NCC1 have not been fully elucidated...
January 6, 2017: Virulence
https://www.readbyqxmd.com/read/28058151/characteristics-of-fundus-autofluorescence-in-active-polypoidal-choroidal-vasculopathy
#10
Zafer Öztaş, Jale Menteş, Serhad Nalçacı, Mine Barış
OBJECTIVES: To define characteristic fundus autofluorescence (FAF) findings in eyes with active polypoidal choroidal vasculopathy (PCV). MATERIALS AND METHODS: Thirty-five eyes of 29 patients with active PCV who were diagnosed at Ege University Faculty of Medicine, Department of Ophthalmology, Retina Division between January 2012 and November 2014 were included in the study. All the patients underwent a complete ophthalmological examination including fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, FAF photography, and indocyanine green angiography (ICGA)...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28053502/neovascular-age-related-macular-degeneration-without-drusen-in-the-fellow-eye-clinical-spectrum-and-therapeutic-outcome
#11
Wing H Chung, Elon H C van Dijk, Danial Mohabati, Greet Dijkman, Suzanne Yzer, Eiko K de Jong, Sascha Fauser, Reinier O Schlingemann, Carel B Hoyng, Camiel J F Boon
PURPOSE: To investigate the clinical characteristics and therapeutic outcome of patients with neovascular age-related macular degeneration (nAMD) in 1 eye, without drusen in the fellow eye. PATIENTS AND METHODS: Medical records of 381 patients were analyzed to identify the cases. The main outcomes included Early Treatment Diabetic Retinopathy Study (ETDRS) best-corrected visual acuity (BCVA) and change in central retinal thickness (CRT). These parameters were reviewed at baseline, first follow-up visit, and after 6, 12, and 24 months...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28052646/ameliorative-potentials-of-quercetin-against-lead-induced-hematological-and-testicular-alterations-in-albino-rats
#12
Mohammed A. Al-Omair, Azza Sedky, Awatef Ali, Hany Elsawy
Lead is one of the oldest environmental and occupational toxins. Health hazards from increased lead exposure as a result of industrial and environmental pollution are recognized. The aim of the present study was to investigate the protective effects of quercetin as a model of an antioxidant drug against the toxic effects of lead acetate on the blood and the testis of rats. The lead concentrations were determined in blood and the testis. Testosterone (T), luteinizing hormone (LH) and follicle stimulating hormone (FSH) were assessed in serum...
28, 2017: Chinese Journal of Physiology
https://www.readbyqxmd.com/read/28052071/impact-of-the-13-valent-pneumococcal-conjugate-vaccine-on-clinical-and-hypoxemic-childhood-pneumonia-over-three-years-in-central-malawi-an-observational-study
#13
Eric D McCollum, Bejoy Nambiar, Rashid Deula, Beatiwel Zadutsa, Austin Bondo, Carina King, James Beard, Harry Liyaya, Limangeni Mankhambo, Marzia Lazzerini, Charles Makwenda, Gibson Masache, Naor Bar-Zeev, Peter N Kazembe, Charles Mwansambo, Norman Lufesi, Anthony Costello, Ben Armstrong, Tim Colbourn
BACKGROUND: The pneumococcal conjugate vaccine's (PCV) impact on childhood pneumonia during programmatic conditions in Africa is poorly understood. Following PCV13 introduction in Malawi in November 2011, we evaluated the case burden and rates of childhood pneumonia. METHODS AND FINDINGS: Between January 1, 2012-June 30, 2014 we conducted active pneumonia surveillance in children <5 years at seven hospitals, 18 health centres, and with 38 community health workers in two districts, central Malawi...
2017: PloS One
https://www.readbyqxmd.com/read/28052047/mechanical-ventilatory-modes-and-cardioventilatory-phase-synchronization-in-acute-respiratory-failure-patients
#14
Claudio Enrico Mazzucco, Andrea Marchi, Vlasta Bari, Beatrice De Maria, Stefano Guzzetti, Ferdinando Raimondi, Emanuele Catena, Davide Ottolina, Carla Amadio, Silvio Cravero, Tommaso Fossali, Riccardo Colombo, Alberto Porta
Cardioventilatory phase synchronization was studied in ten critically ill patients admitted in intensive care unit (ICU) for acute respiratory failure under two mechanical ventilatory modes: i) pressure controlled ventilation (PCV); ii) pressure support ventilation (PSV). The two modalities were administered to the same patient in different times in a random order. Cardioventilatory phase interactions were typified by plotting the relative position of a heartbeat, detected from the electrocardiogram and collected in n groups, within m ventilatory cycles as a function of the progressive cardiac beat number via the synchrogram...
January 4, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28049447/invasive-pneumococcal-disease-among-adults-in-japan-april-2013-to-march-2015-disease-characteristics-and-serotype-distribution
#15
Munehisa Fukusumi, Bin Chang, Yoshinari Tanabe, Kengo Oshima, Takaya Maruyama, Hiroshi Watanabe, Koji Kuronuma, Kei Kasahara, Hiroaki Takeda, Junichiro Nishi, Jiro Fujita, Tetsuya Kubota, Tomimasa Sunagawa, Tamano Matsui, Kazunori Oishi
BACKGROUND: In Japan, the clinical characteristics and recent serotype distribution among adult patients of invasive pneumococcal disease (IPD) have not been fully investigated since the introduction of the pneumococcal conjugate vaccine (PCV) in children. From November 2010, PCV7 was encouraged by an official program, funded by government, subsequently included in the routine schedule in April 2013, and replaced with a PCV13 in November 2013. METHODS: Between April 2013 and March 2015, patients with IPD older than 15 years were evaluated based on the enhanced national surveillance in ten prefectures of Japan...
January 3, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28039643/respiratory-dynamics-and-dead-space-to-tidal-volume-ratio-of-volume-controlled-versus-pressure-controlled-ventilation-during-prolonged-gynecological-laparoscopic-surgery
#16
Ming Lian, Xiao Zhao, Hong Wang, Lianhua Chen, Shitong Li
BACKGROUND: Laparoscopic operations have become longer and more complex and applied to a broader patient population in the last decades. Prolonged gynecological laparoscopic surgeries require prolonged pneumoperitoneum and Trendelenburg position, which can influence respiratory dynamics and other measurements of pulmonary function. We investigated the differences between volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) and tried to determine the more efficient ventilation mode during prolonged pneumoperitoneum in gynecological laparoscopy...
December 30, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/28032483/indirect-effects-of-pneumococcal-conjugate-vaccines-in-national-immunization-programs-for-children-on-adult-pneumococcal-disease
#17
REVIEW
Young Keun Kim, David LaFon, Moon H Nahm
The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have included PCVs in national immunization programs for children, the incidence of invasive pneumococcal disease caused by vaccine type Streptococcus pneumoniae has declined markedly, not only among the vaccinated pediatric population, but also among unvaccinated adults. In this review, we present a concise overview of the indirect effects of mass pediatric PCV immunization on unvaccinated adults...
December 2016: Infection & Chemotherapy
https://www.readbyqxmd.com/read/28031178/otitis-prone-children-produce-functional-antibodies-to-pneumolysin-and-pneumococcal-polysaccharides
#18
Lea-Ann S Kirkham, Selma P Wiertsema, Karli J Corscadden, Tulia Mateus, Gemma L Mullaney, Guicheng Zhang, Peter C Richmond, Ruth B Thornton
BACKGROUND: The pneumococcus is a major otitis media (OM) pathogen but data are conflicting on whether otitis-prone children have impaired humoral immunity to pneumococcal antigens. We and others have shown that otitis-prone and healthy children have similar antibody titres to pneumococcal proteins and polysaccharides (vaccine and non-vaccine type), however the quality of antibodies from otitis-prone children has not been investigated. Antibody function, rather than titre, is considered to better correlate with protection from pneumococcal disease...
December 28, 2016: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28030336/genetic-diversity-among-babesia-rossi-detected-in-naturally-infected-dogs-in-abeokuta-nigeria-based-on-18s-rrna-gene-sequences
#19
Michael I Takeet, Adeoye J Oyewusi, Simon A V Abakpa, Olukayode O Daramola, Sunday O Peters
Adequate knowledge of the genetic diversity among Babesia species infecting dogs is necessary for a better understanding of the epidemiology and control of canine babesiosis. Hence, this study determined the genetic diversity among the Babesia rossi detected in dogs presented for routine examination in Veterinary Hospitals in Abeokuta, Nigeria. Blood were randomly collected from 209 dogs. Field-stained thin smears were made and DNA extracted from the blood. Partial region of the 18S small subunit ribosomal RNA (rRNA) gene was amplified, sequenced and analysed...
March 1, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/28029292/ability-of-clinicopathologic-variables-and-clinical-examination-findings-to-predict-race-elimination-in-endurance-horses
#20
C Langdon Fielding, Chloe A Meier, Greg K Fellers, K Gary Magdesian
OBJECTIVE To compare results of point-of-care laboratory testing with standard veterinary clinical examination findings at a single time point during endurance competition to identify horses at risk for elimination. ANIMALS 101 endurance horses participating in the 2013 Western States 160-km (100-mile) endurance ride. PROCEDURES At the 58-km checkpoint, blood samples were collected from all horses. Samples were analyzed for pH, Pco2, base excess, anion gap, PCV, and whole blood concentrations of sodium, potassium, chloride, total carbon dioxide, BUN, glucose, and bicarbonate...
January 2017: American Journal of Veterinary Research
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