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https://www.readbyqxmd.com/read/28807606/effectiveness-of-different-vaccine-schedules-for-heptavalent-and-13-valent-conjugate-vaccines-against-pneumococcal-disease-in-the-community-of-madrid
#1
P Latasa, M Ordobás, M Garrido-Estepa, A Gil de Miguel, J C Sanz, M D Barranco, E Insúa, L García-Comas
INTRODUCTION: The heptavalent pneumococcal conjugate vaccine (PCV-7) was added to the childhood routine vaccination program in the Community of Madrid in November of 2006 with 3+1 recommended doses and a catch-up for those under 2years old. In June 2010, PCV-7 was replaced by 13-valent vaccine (PCV-13) with 2+1 recommended doses. In July of 2012, the PCV-13 was removed from the funded program and reintroduced again (2+1 recommended doses) in December 2014. In between, children were vaccinated privately with 3+1 recommended doses of PCV-13...
August 11, 2017: Vaccine
https://www.readbyqxmd.com/read/28807317/validation-of-the-famacha%C3%A2-system-in-south-american-camelids
#2
Bobby E Storey, Lisa H Williamson, Sue B Howell, Thomas H Terrill, Roy Berghaus, Anand N Vidyashankar, Ray M Kaplan
Haemonchus contortus resistant to multiple anthelmintics threaten the viability of the small ruminant industry in areas where this parasite is prevalent. In response to this situation, the FAMACHA© system was developed and validated for use with small ruminants as a way to detect clinical anemia associated with haemonchosis. Given that H. contortus and multiple anthelmintic resistance is a similar problem in camelids, the FAMACHA© system might also provide the same benefits. To address this need, a validation study of the FAMACHA© system was conducted on 21 alpaca and llama farms over a 2-year period...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28804921/serum-thymidine-kinase-1-canine-c-reactive-protein-haptoglobin-and-vitamin-d-concentrations-in-dogs-with-immune-mediated-hemolytic-anemia-thrombocytopenia-and-polyarthropathy
#3
M Grobman, H Outi, H Rindt, C Reinero
BACKGROUND: Relapses of immune-mediated hemolytic anemia (IMHA), thrombocytopenia (ITP), or polyarthropathy (IMPA) occur despite normal hematologic and cytologic parameters. Thymidine kinase 1 (TK1), canine C-reactive protein (c-CRP), haptoglobin (HPT), and 25-Hydroxyvitamin-D (25(OH)D) might be adjunct to current monitoring strategies. HYPOTHESIS/OBJECTIVES: Compare serum concentrations of TK1, c-CRP, HPT, and 25(OH)D in dogs with well- and poorly controlled primary IMHA, ITP, or IMPA...
August 14, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28803551/hospitalisation-for-lower-respiratory-tract-infection-in-children-in-the-province-of-quebec-canada-before-and-during-the-pneumococcal-conjugate-vaccine-era
#4
G Anderson, G Deceuninck, Z Zhou, F D Boucher, Y Bonnier Viger, R Gilca, P DE Wals
Streptococcus pneumoniae is an important cause of community-acquired pneumonia and pneumococcal conjugate vaccines (PCVs) may reduce this burden. This study's goal was to analyse trends in lower respiratory tract infections (LRTI) hospitalisations before and during a routine vaccination programme targeting all newborns with PCV was started in the province of Quebec, Canada in December 2004. The study population included hospital admissions with a main diagnosis of LRTI among 6-59 month-old Quebec residents from April 2000 to December 2014...
August 14, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28802367/impact-of-pneumococcal-conjugate-vaccines-on-otitis-media-a-review-of-measurement-and-interpretation-challenges
#5
REVIEW
Ivo Vojtek, Marcus Nordgren, Bernard Hoet
Acute otitis media (AOM) is among the most frequent childhood diseases and is caused by various bacterial and viral etiological agents. In this article, we provide an overview of published studies assessing the impact of higher-valent pneumococcal conjugate vaccines (PCVs) on AOM. In some instances, reports of PCV impact on complications of AOM have been included. While randomized controlled trials (RCTs) allow for the most precise assessment of vaccine efficacy against AOM, observational studies provide answers to questions regarding the public health value of these vaccines in real-life settings...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28801615/choroidal-remodeling-in-age-related-macular-degeneration-and-polypoidal-choroidal-vasculopathy-a-12-month-prospective-study
#6
Daniel Shu Wei Ting, Yasuo Yanagi, Rupesh Agrawal, Hwei Yee Teo, Sophia Seen, Ian Yew San Yeo, Ranjana Mathur, Choi Mun Chan, Shu Yen Lee, Edmund Yick Mun Wong, Doric Wong, Tien Yin Wong, Gemmy Chui Ming Cheung
Choroid thinning occurs in age-related macular degeneration (AMD). However, it remains unclear whether the reduction is due to reduction in choroidal vessels or shrinkage of choroidal stroma, or both. The purpose of this study was to evaluate the changes of the choroidal vascular and stromal area in 118 patients with typical AMD (t-AMD) and polypoidal choroidal vasculopathy (PCV) over a 12-month period. We used spectral-domain optical coherence tomography (SD-OCT) with enhanced depth imaging (EDI) mode to measure the subfoveal choroidal thickness (CT), central retinal thickness (CRT) and choroidal vascularity index (CVI - ratio of luminal area to total choroidal area)...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28795781/evaluation-of-the-use-of-shock-index-in-identifying-acute-blood-loss-in-healthy-blood-donor-dogs
#7
Erin E McGowan, Kimberly Marryott, Kenneth J Drobatz, Erica L Reineke
OBJECTIVE: To determine if shock index (SI) would increase following blood donation and if it would be a more sensitive assessment of acute blood loss as compared with heart rate (HR), blood pressure, and plasma lactate. DESIGN: Prospective study. SETTING: University teaching hospital. ANIMALS: Twenty client-owned clinically normal dogs. INTERVENTIONS: Peripheral venous blood measurements and blood donation...
August 10, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28795619/hematological-and-molecular-characterization-of-a-novel-hb-a2-variant-with-homozygous-%C3%AE-thalassemia-2-in-a-southern-thai-individual
#8
Manit Nuinoon, Nutjaree Jeenduang, Aumpika Kesornsit, Dararat Horpet, Thunyaluk Plyduang
We report here the hematological and molecular features of a novel δ-globin chain variant found in a Southern Thai woman. Her complete blood count was as follows: red blood cell (RBC) count 5.90 × 10(12)/L, hemoglobin concentration (Hb) 12.6 g/dL, packed cell volume (PCV) 0.41 L/L, mean corpuscular volume (MCV) 69.5 fL, mean corpuscular Hb (MCH) 21.4 pg, mean corpuscular Hb concentration (MCHC) 30.7 g/dL and RBC distribution width (RDW) 13.1%. The blood smear demonstrated microcytic hypochromic RBCs suggestive of thalassemia trait...
August 10, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28792887/the-genetic-basis-for-the-selection-of-dairy-goats-with-enhanced-resistance-to-gastrointestinal-nematodes
#9
Felix Heckendorn, Anna Bieber, Steffen Werne, Anastasios Saratsis, Veronika Maurer, Chris Stricker
Gastrointestinal nematodes (GIN) severely affect small ruminant production worldwide. Increasing problems of anthelmintic resistance have given strong impetus to the search for alternative strategies to control GIN. Selection of animals with an enhanced resistance to GIN has been shown to be successful in sheep. In goats, the corresponding information is comparatively poor. Therefore, the present study was designed to provide reliable data on heritabilities of and genetic correlations between phenotypic traits linked to GIN and milk yield in two major dairy goat breeds (Alpine and Saanen)...
2017: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/28783866/hematologic-and-plasma-chemistry-ris-for-cultured-striped-catfish-pangasius-hypophthalmus-in-recirculating-aquaculture-systems
#10
Oscar A Galagarza, David D Kuhn, Stephen A Smith, Terry C Hrubec
BACKGROUND: Striped catfish (Pangasius hypophthalmus) is a valuable aquaculture fish species produced primarily in Southeast Asia. In the United States, it is bred as an ornamental species. Striped catfish has high productivity and great demand in numerous countries around the world, yet little is known about its normal physiology. OBJECTIVES: The objective of this study was to establish hematologic and blood chemistry RIs for healthy juvenile Striped catfish. METHODS: Blood samples were collected from 70 Striped catfish raised in recirculating aquaculture systems...
August 7, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28783380/streptococcus-pneumoniae-serotype-19a-worldwide-epidemiology
#11
Raul Isturiz, Heather L Sings, Betsy Hilton, Adriano Arguedas, Ralf-René Reinert, Luis Jodar
Streptococcus pneumoniae causes mucosal and invasive diseases with high morbidity and mortality. Introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) into routine infant immunization programs worldwide resulted in serotype 19A becoming a leading cause of the remaining pneumococcal disease burden in vaccinated and unvaccinated individuals. This article reviews the impact of the latest generation PCVs (10-valent PCV, PCV10, and 13-valent PCV, PCV13) on serotype 19A. Areas covered: This article covers immune responses elicited by PCV7, PCV10 and PCV13 against serotype 19A and their impact on nasopharyngeal (NP) carriage and disease in vaccinated and unvaccinated populations using data from surveillance systems, randomized controlled trials, and observational studies...
August 7, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28776337/changes-in-the-serotype-distribution-among-antibiotic-resistant-carriage-streptococcus-pneumoniae-isolates-in-children-after-the-introduction-of-the-extended-valency-pneumococcal-conjugate-vaccine
#12
Joon Kee Lee, Ki Wook Yun, Eun Hwa Choi, Sun Jung Kim, Seong Yeon Lee, Hoan Jong Lee
This study investigated the serotype distribution and antimicrobial resistance of 3,820 nasopharyngeal Streptococcus pneumoniae isolates from infants and children who presented with respiratory symptoms at Seoul National University Children's Hospital from July 2010 to June 2015 after the introduction of the extended-valency pneumococcal conjugate vaccines (PCVs). Serotypes and antimicrobial susceptibility were determined using the Quellung reaction and E-test, respectively. S. pneumoniae was isolated from 397 (10...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28767518/bayesian-model-averaging-with-change-points-to-assess-the-impact-of-vaccination-and-public-health-interventions
#13
Esra Kürüm, Joshua L Warren, Cynthia Schuck-Paim, Roger Lustig, Joseph A Lewnard, Rodrigo Fuentes, Christian A W Bruhn, Robert J Taylor, Lone Simonsen, Daniel M Weinberger
BACKGROUND: Pneumococcal conjugate vaccines (PCVs) prevent invasive pneumococcal disease and pneumonia. However, some low- and middle-income countries have yet to introduce PCV into their immunization programs due, in part, to lack of certainty about the potential impact. Assessing PCV benefits is challenging because specific data on pneumococcal disease is often lacking, and it can be difficult to separate the effects of factors other than the vaccine that could also affect pneumococcal disease rates...
July 31, 2017: Epidemiology
https://www.readbyqxmd.com/read/28764232/co-inheritance-of-haemoglobin-d-punjab-and-beta-thalassemia-a-rare-variant
#14
Kalyan Mansukhbhai Shekhda, Alpa C Leuva, Jyoti G Mannari, Aashka Vikas Ponda, Amee Amin
Haemoglobinopathies are a frequent cause of anaemia in Northwestern India due to traditional practices of consanguineous marriages. Haemoglobin D-Punjab is one of the most common subvariants (55%) of haemoglobin D, which can be inherited as a homozygous or a heterozygous trait with other haemoglobinopathies. Though, haemoglobin D-Punjab is commonly seen, a heterozygous trait with beta thalassemia is a very rare presentation. Here, we present a rare case of co-inheritance of haemoglobin D-Punjab and beta thalassemia in a 19-year-old male of Indian origin...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763425/frequency-of-acute-otitis-media-in-children-under-24-months-of-age-before-and-after-the-introduction-of-the-10-valent-pneumococcal-conjugate-vaccine-into-the-national-immunization-program-in-chile
#15
Andrés Rosenblut, Macarena Rosenblut, Karen García, Ximena Maul
BACKGROUND: Streptococcus pneumoniae is the leading cause of acute otitis media (AOM). Pneumococcal non-typable Haemophilus influenzae Protein D Conjugate Vaccine (PCV-10) was introduced to the Chilean national immunization program (NIP) in 2011. The aim of this study was to estimate the frequency of AOM in children < 24 months of age attending the Emergency Department (ED) of Hospital Sótero del Río (HSR) 4 years before and 4 years after the introduction of PCV-10 in the Chilean NIP...
July 31, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28761460/relationships-between-oxidative-stress-liver-and-erythrocyte-injury-trace-elements-and-parasite-burden-in-sheep-naturally-infected-with-dicrocoelium-dendriticum
#16
Hadi Samadieh, Gholam-Reza Mohammadi, Mohsen Maleki, Hassan Borji, Mohammad Azizzadeh, Mohammad Heidarpour
BACKGROUND: The aim of this study was to investigate the role of oxidative stress in the pathology of ovine dicrocoeliasis. METHODS: During Dec 2013 - Oct 2014, seventy-two sheep (1-3 years) with liver dicrocoeliasis along with 47 healthy sheep were selected from animals admitted for slaughtering at slaughterhouse located in Neyshabour, Razavi Khorasan Province, Iran. RESULTS: In comparison to healthy control, the malondialdehyde (MDA) level and serum total antioxidant capacity were significantly higher in the parasitized group (P<0...
January 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28758135/effect-of-chitosan-and-liposome-nanoparticles-as-adjuvant-codelivery-on-the-immunoglobulin-g-subclass-distribution-in-a-mouse-model
#17
Agus Haryono, Korrie Salsabila, Witta Kartika Restu, Sri Budi Harmami, Dodi Safari
BACKGROUND: We investigate the immunogenic properties of chitosan and liposome nanoparticles as adjuvant codelivery against a commercial pneumococcal conjugate vaccine (PCV) in an animal model. METHODS: The chitosan and liposome nanoparticles were prepared by ionic gelation and dry methods, respectively. The PCV immunization was performed intradermally in the presence of adjuvants and booster injections which were given without an adjuvant. The Quil-A® was used as a control adjuvant...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28753857/the-impact-of-plasmacytoid-variant-histology-on-the-survival-of-patients-with-urothelial-carcinoma-of-bladder-after-radical-cystectomy
#18
Qiang Li, Melissa Assel, Nicole E Benfante, Eugene J Pietzak, Harry W Herr, Machele Donat, Eugene K Cha, Timothy F Donahue, Bernard H Bochner, Guido Dalbagni
BACKGROUND: The clinical significance of the plasmacytoid variant (PCV) in urothelial carcinoma (UC) is currently lacking. OBJECTIVE: To compare clinical outcomes of patients with any PCV with that of patients with pure UC treated with radical cystectomy (RC). DESIGN, SETTING, AND PARTICIPANTS: We identified 98 patients who had pathologically confirmed PCV UC and 1312 patients with pure UC and no variant history who underwent RC at our institution between 1995 and 2014...
June 27, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28751897/comparative-agronomic-performance-and-reaction-to-fusarium-wilt-of-lens-culinaris-%C3%A3-l-orientalis-and-l-culinaris-%C3%A3-l-ervoides-derivatives
#19
Mohar Singh, Jai C Rana, Badal Singh, Sandeep Kumar, Deep R Saxena, Ashok Saxena, Aqeel H Rizvi, Ashutosh Sarker
The development of transgressive phenotype in the segregating populations has been speculated to contribute to niche divergence of hybrid lineages, which occurs most frequently at larger genetic distances. Wild Lens species are considered to be more resistant against major biotic and abiotic stresses than that of the cultivated species. In the present study, we assessed the comparative agronomic performance of lentil (Lens culinaris subsp. culinaris) inter-sub-specific (L. culinaris subsp. orientalis) and interspecific (L...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28750863/microscopic-and-molecular-identification-of-hemotropic-mycoplasmas-in-south-american-coatis-nasua-nasua
#20
Michelle P Cubilla, Leonilda C Santos, Wanderlei de Moraes, Zalmir S Cubas, Christian M Leutenegger, Marko Estrada, LeAnn L Lindsay, Edvaldo S Trindade, Célia Regina C Franco, Rafael F C Vieira, Alexander W Biondo, Jane E Sykes
Hemoplasmas were detected in two apparently healthy captive South American coatis (Nasua nasua) from southern Brazil during an investigation for vector-borne pathogens. Blood was subjected to packed cell volume (PCV) determination, a commercial real-time PCR panel for the detection of Anaplasma spp., Babesia spp., Bartonella spp., Hepatozoon spp., Leishmania spp., Mycoplasma haemofelis, 'Candidatus Mycoplasma turicensis', 'Candidatus Mycoplasma haemominutum', Neorickettsia risticii, Rickettsia rickettsii and Leptospira spp...
August 2017: Comparative Immunology, Microbiology and Infectious Diseases
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