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sleep obstructive apnea

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https://www.readbyqxmd.com/read/29149468/pneumoparotitis-as-a-complication-of-long-term-oronasal-positive-airway-pressure-for-sleep-apnea
#1
Andrew J Goates, Daniel J Lee, Joan E Maley, Phillip C Lee, Henry T Hoffman
BACKGROUND: Parotid swelling is rarely caused by pneumoparotitis from retrograde insufflation of air into Stensen's duct. Previous reports have identified occupational exposures, self-induced habits, exercise, spirometry, and short-term positive pressure airway ventilation as causes of salivary duct insufflation. METHODS: We present 2 cases of pneumoparotitis in patients on long-term oronasal continuous positive airway pressure (CPAP) for obstructive sleep apnea...
November 17, 2017: Head & Neck
https://www.readbyqxmd.com/read/29149438/patient-predicted-sleep-position-vs-hst-data-a-tendency-to-underestimate-supine-sleep
#2
Adam J Sorscher, Anthony P Anzivino, Todd Mackenzie
PURPOSE: The purpose of this study is to measure people's accuracy when they estimate what proportion of their nightly sleep at home is supine vs. non-supine. METHODS: A series of patients referred for obstructive sleep apnea (OSA) evaluation were asked if they "knew with confidence" how they slept with regard to their body position. "Yes" responders were then asked to estimate what percentage of their sleep was supine vs. non-supine. This value was compared with the actual proportion of supine vs...
November 17, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29148894/metabolic-profile-in-patients-with-mild-obstructive-sleep-apnea
#3
Luciana Oliveira E Silva, Thais M Guimarães, Gabriela P Luz, Glaury Coelho, Luciana Badke, Ildonete R Almeida, Aline Millani-Carneiro, Sergio Tufik, Lia Bittencourt, Sonia M Togeiro
BACKGROUND: Mild obstructive sleep apnea (OSA) is a highly prevalent disorder in adults. However, it is not clear whether mild OSA has significant metabolic complications. This study examined the prevalence of metabolic syndrome (MS) in patients with mild OSA compared to control group. METHODS: Adults (18-65 years of age) of both genders with a body mass index (BMI) ≤35 kg/m(2) were included. The mild OSA group comprised of patients with an apnea-hypopnea index (AHI) score of ≥5 but ≤15 events/hr of sleep, independent of other symptoms...
November 17, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29147581/review-of-and-updates-on-hypertension-in-obstructive-sleep-apnea
#4
REVIEW
Masood Ahmad, Devan Makati, Sana Akbar
Obstructive sleep apnea (OSA) is a prevalent sleep disorder as is hypertension (HTN) in the 21st century with the rising incidence of obesity. Numerous studies have shown a strong association of OSA with cardiovascular morbidity and mortality. There is overwhelming evidence supporting the relationship between OSA and hypertension (HTN). The pathophysiology of HTN in OSA is complex and dependent on various factors such as sympathetic tone, renin-angiotensin-aldosterone system, endothelial dysfunction, and altered baroreceptor reflexes...
2017: International Journal of Hypertension
https://www.readbyqxmd.com/read/29145148/honokiol-protects-pancreatic-%C3%AE-cell-against-high-glucose-and-intermittent-hypoxia-induced-injury-by-activating-nrf2-are-pathway-in-vitro-and-in-vivo
#5
Chen-Guang Li, Chang-Lin Ni, Min Yang, Yun-Zhao Tang, Zhu Li, Yan-Juan Zhu, Zhen-Huan Jiang, Bei Sun, Chun-Jun Li
Obstructive sleep apnea hypopnea syndrome (OSAHS) is associated with glucose intolerance, insulin resistance and type 2 diabetes mellitus (T2DM). Although several studies have revealed that intermittent hypoxia (IH) in OSAHS may further aggravate pancreatic β cell damage and promote the evolution of type 2 diabetes (T2DM) by increasing oxidative stress, the underlying mechanisms are unclear. Honokiol, a potent radical scavenger, has been demonstrated to ameliorate oxidative stress in many cases. The present study aimed to explore the potential mechanism of IH and diabetes synergistically damage and destruct the pancreatic β cell, examine the effects of honokiol on ameliorating pancreatic β cell injury in this context and explore the mechanism of such effects...
November 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29144628/overactive-bladder-syndrome-and-bladder-wall-thickness-in-patients-with-obstructive-sleep-apnea-syndrome
#6
Zahide Yilmaz, Bekir Voyvoda, Pinar Bekdik Şirinocak
OBJECTIVE: The main objective of the present study was to evaluate the presence of overactive bladder (OAB) syndrome, nocturia, urgency, and urge incontinence in patients with obstructive sleep apnea syndrome (OSAS), and measure bladder wall thickness (BWT) in these patients. MATERIALS AND METHODS: The patient group was composed of 38 patients with OSAS. The control group was composed of 15 healthy individuals. All patients were evaluated using the Epworth Sleepiness Scale (ESS) and Overactive Bladder Symptom Score (OABSS)...
November 19, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29144513/predictors-of-heart-rhythm-disturbances-in-hypertensive-obese-patients-with-obstructive-sleep-apnea
#7
Lyudmila Sergeevna Korostovtseva, Nadezhda Edvinovna Zvartau, Oxana Petrovna Rotar, Yurii Vladimirovich Sviryaev, Aleksandra Olegovna Konradi
Objective: To assess the incidence and predictors of heart rhythm and conduction disturbances in hypertensive obese patients with and without obstructive sleep apnea (OSA). Methods: This is an open, cohort, prospective study. Out of 493 screened patients, we selected 279 hypertensive, obese individuals without severe concomitant diseases: 75 patients without sleep-disordered breathing (non-SDB group), and 204 patients with OSA (OSA group). At baseline, all patients underwent examination, including ECG, Holter ECG monitoring, and sleep study...
September 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29142656/pharyngeal-airway-dimensions-and-head-posture-in-obstructive-sleep-apnea-patients-with-and-without-morphological-deviations-in-the-upper-cervical-spine
#8
Liselotte Sonnesen, Arne Petersson, Søren Berg, Palle Svanholt
Objectives: The aim of the study was to analyse differences in pharyngeal airway dimensions and head posture between obstructive sleep apnea patients with and without morphological deviations in the upper cervical spine and to analyse associations between pharyngeal airway dimensions and head posture in the total sample. Material and Methods: The sample comprised 53 obstructive sleep apnea (OSA) patients of which 32.1% had upper spine morphological deviations. Accordingly two groups were defined: 17 OSA patients with morphological deviations in the upper spine and 36 without upper spine deviations...
July 2017: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29142091/physiological-and-pathophysiological-firing-properties-of-single-postganglionic-sympathetic-neurons-in-humans
#9
Vaughan G Macefield, B Gunnar Wallin
It has long been known from microneurographic recordings in human subjects that activity of postganglionic sympathetic axons occurs as spontaneous bursts, with muscle sympathetic nerve activity (MSNA) exhibiting strong cardiac rhythmicity via the baroreflex and skin sympathetic nerve activity (SSNA) showing much weaker cardiac modulation. Here we review the firing properties of single sympathetic neurons, obtained using highly selective microelectrodes. Individual vasoconstrictor neurons supplying muscle or skin, or sudomotor neurones supplying sweat glands, always discharge with a low firing probability (~30%) and at very low frequencies (~0...
November 15, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29141301/-obstructive-sleep-apnea-hypopnea-syndrome-complicated-with-obesity-hypoventilation-syndrome-a-case-report
#10
Z Y Zhang, H H Lu, Q W Li, P Lin
No abstract text is available yet for this article.
November 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29141154/obstructive-sleep-apnea-and-cardiovascular-disease-rem-sleep-matters
#11
Babak Mokhlesi, Andrew W Varga
No abstract text is available yet for this article.
November 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29139016/methodological-strategies-in-using-home-sleep-apnea-testing-in-research-and-practice
#12
REVIEW
Jennifer N Miller, Paula Schulz, Bunny Pozehl, Douglas Fiedler, Alissa Fial, Ann M Berger
PURPOSE: Home sleep apnea testing (HSAT) has increased due to improvements in technology, accessibility, and changes in third party reimbursement requirements. Research studies using HSAT have not consistently reported procedures and methodological challenges. This paper had two objectives: (1) summarize the literature on use of HSAT in research of adults and (2) identify methodological strategies to use in research and practice to standardize HSAT procedures and information. METHODS: Search strategy included studies of participants undergoing sleep testing for OSA using HSAT...
November 14, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29138878/higher-cost-of-hospitalizations-for-non-cardiac-diagnoses-in-adults-with-congenital-heart-disease
#13
Michael D Seckeler, Ian D Thomas, Jennifer Andrews, Omar Meziab, Tabitha Moe, Elissa Heller, Scott E Klewer
Adults with congenital heart disease (CHD) are a rapidly increasing population and their impact on healthcare resources is not fully understood. The purpose of this study was to describe the costs of hospitalizations for non-cardiac disease for adults with CHD. We conducted a retrospective review of hospital discharge data from the University HealthSystem Consortium Clinical Data Base/Resource Manager from January 2011 through December 2013. Patients were ≥ 18 years old at admission with any ICD-9 code for moderate or high severity CHD; cardiac surgical admissions were excluded...
November 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29137477/circulating-lipopolysaccharide-binding-protein-and-carotid-intima-media-thickness-in-obstructive-sleep-apnea
#14
I Trojova, M Kozarova, D Petrasova, Z Malachovska, I Paranicova, P Joppa, R Tkacova
Circulating lipopolysaccharide-binding protein (LBP), a metabolic endotoxemia marker, was identified as an independent predictor of atherosclerosis. Although increases in carotid intima-media thickness (CIMT) were repeatedly reported in obstructive sleep apnea (OSA), neither the role of OSA in metabolic endotoxemia nor of LBP in early atherosclerosis were explored in patients with OSA. At a tertiary university hospital we investigated the relationships between OSA, LBP and CIMT in 117 men who underwent full polysomnography and CIMT assessment by B-mode ultrasound...
November 10, 2017: Physiological Research
https://www.readbyqxmd.com/read/29135910/sleep-disordered-breathing-in-children-with-recurrent-wheeze-asthma-a-single-centre-study
#15
Marco Zaffanello, Emma Gasperi, Laura Tenero, Michele Piazza, Angelo Pietrobelli, Luca Sacchetto, Franco Antoniazzi, Giorgio Piacentini
The relationship between asthma and sleep-disordered breathing is bidirectional due to common risk factors that promote airway inflammation. Obstructive sleep-disordered breathing and recurrent wheeze/asthma are conditions that involve the upper and the lower respiratory system, respectively. The aim of the present study was to investigate the sleep disordered breathing in children with recurrent wheeze/asthma. This was a retrospective study concerning children older than 2 years who underwent-between January 2014 and November 2016-an in-laboratory overnight polygraphic study...
November 14, 2017: Children
https://www.readbyqxmd.com/read/29135775/adjustment-for-variable-adherence-under-hierarchical-structure-instrumental-variable-modeling-through-compound-residual-inclusion
#16
Tyson H Holmes, Donna M Zulman, Clete A Kushida
BACKGROUND: Variable adherence to assigned conditions is common in randomized clinical trials. OBJECTIVES: A generalized modeling framework under longitudinal data structures is proposed for regression estimation of the causal effect of variable adherence on outcome, with emphasis upon adjustment for unobserved confounders. RESEARCH DESIGN: A nonlinear, nonparametric random-coefficients modeling approach is described. Estimates of local average treatment effects among compliers can be obtained simultaneously for all assigned conditions to which participants are randomly assigned within the trial...
December 2017: Medical Care
https://www.readbyqxmd.com/read/29135515/association-between-allergic-and-nonallergic-rhinitis-and-obstructive-sleep-apnea
#17
Ming Zheng, Xiangdong Wang, Luo Zhang
PURPOSE OF REVIEW: Allergic rhinitis and nonallergic rhinitis (NAR) are common disorders, which have been considered as potential risk factors for obstructive sleep apnea (OSA). This review summarizes the proposed underlying pathophysiological mechanisms to provide a better understanding of the relationship between these conditions. RECENT FINDINGS: In adults, allergic rhinitis and NAR may be considered as symptoms potentiating, rather than risk potentiating factors in the pathophysiology of OSA, whereas in children, these are considered to be independent predictors for sleep-disordered breathing (SDB) and failure of adeno-tonsillectomy, the recommended first-line therapy for children with OSA...
November 14, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29134776/acute-chest-syndrome-among-children-hospitalized-with-vaso-occlusive-crisis-a-nationwide-study-in-the-united-states
#18
Takuto Takahashi, Yusuke Okubo, Atsuhiko Handa
PURPOSE: Acute chest syndrome (ACS) is a common complication among pediatric inpatients with sickle cell disease and vaso-occlusive crisis (VOC). However, little is known about the factors associated with ACS complication. The present study assessed the epidemiological features of children hospitalized with VOC and ascertained factors associated with ACS complication. METHODS: Hospital discharge records of patients with VOC aged <20 years were obtained for the years 2003, 2006, 2009, and 2012 from the Kids' Inpatient Database...
November 14, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29134423/perioperative-respiratory-complications-current-evidence-and-strategy-discussed-in-2017-ja-symposium
#19
K Hirota, M Yamakage, S Hashimoto, T Asai, S Isono
Respiratory management during general anesthesia aims to safely secure the airway and maintain adequate ventilation to deliver oxygen to the vital organs, maintaining homeostasis even during surgery. Despite its clinical importance, anesthesiologists often encounter difficulties in properly managing respiration during the perioperative period, leading to severe respiratory complications. In this year's JA symposium, 5 editorial board members of Journal of Anesthesia (JA) who are experts in the field of respiratory management in anesthesia discussed the following topics: quitting smoking before surgery: exposure to passive smoke is damaging to children, ventilator-associated pneumonia, high inspiratory oxygen concentration and lung injury, aspiration pneumonia, and postoperative respiratory management strategy in patients with obstructive sleep apnea...
November 13, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/29133382/atrial-fibrillation-and-obstructive-sleep-apnea-beyond-the-pulmonary-veins
#20
EDITORIAL
Konstantinos C Siontis, Hakan Oral
No abstract text is available yet for this article.
November 2017: Circulation. Arrhythmia and Electrophysiology
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