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sleep obstructive apnea

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https://www.readbyqxmd.com/read/28650781/rapid-maxillary-expansion-in-obstructive-sleep-apnea-in-young-patients-cardio-respiratory-monitoring
#1
Alfio Buccheri, Fabio Chinè, Giovanni Fratto, Licia Manzon
OBJECTIVE(S): Obstructive sleep apnea syndrome (OSAS) is a respiratory disorder which affects from 1 to 3 % of people during development. OSAS treatment may be pharmacological, surgical or based on application of intraoral devices to increase nasal respiratory spaces. The purpose of this study was to determine the efficacy of the Rapid Maxillary Expander in OSAS young patients by measuring cardio-respiratory monitoring parameters (AHI, the average value of complete and incomplete obstructed respiration per hour of sleep, and SAO2, the percentage of oxygen saturation)...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28649465/dietary-and-cardio-metabolic-risk-factors-in-patients-with-obstructive-sleep-apnea-cross-sectional-study
#2
Marta Stelmach-Mardas, Marcin Mardas, Khalid Iqbal, Magdalena Kostrzewska, Tomasz Piorunek
BACKGROUND: Little is known about the role of dietary intake in obstructive sleep apnea (OSA), which could prove important in improving clinical outcomes for people with obesity and/or cardiovascular disease within these populations. Reduction in energy intake typically results in weight loss, markedly improving metabolic parameters and ameliorating OSA severity. The aim of this study was to evaluate the association of dietary and cardio-metabolic risk factors with OSA severity. METHODS: This was a cross-sectional study...
2017: PeerJ
https://www.readbyqxmd.com/read/28648911/influence-of-bimaxillary-surgery-on-pharyngeal-airway-in-class-iii-deformities-and-effect-on-sleep-apnea-a-stop-bang-questionnaire-and-cone-beam-computed-tomography-study
#3
Narayan H Gandedkar, Chai Kiat Chng, Yong Chen Por, Vincent Kok Leng Yeow, Andrew Ow Tjin Chiew, Seah Tian Ee
PURPOSE: To evaluate pharyngeal airway space (PAS; nasopharyngeal, oropharyngeal, and total airway) volume and the correlation of an obstructive sleep apnea (OSA) and hypopnea syndrome screening questionnaire (STOP-BANG) with various mandibular setbacks during bimaxillary surgery and compare these findings with an age- and gender-matched skeletal Class I control group. PATIENTS AND METHODS: This retrospective cohort study was composed of patients with skeletal Class III discrepancy who underwent bimaxillary jaw surgery and were assessed with STOP-BANG score, cephalometry, and cone-beam computed tomography (of the PAS)...
June 1, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28648418/longitudinal-ventricular-systolic-dysfunction-in-patients-with-very-severe-obstructive-sleep-apnea-a-case-control-study-using-speckle-tracking-imaging
#4
Mithun Jacob Varghese, Gautam Sharma, Garima Shukla, Sandeep Seth, Sundeep Mishra, Anupama Gupta, Vinay Kumar Bahl
OBJECTIVE: Obstructive sleep apnea (OSA) is a prevalent condition that is increasingly recognized to be associated with cardiovascular disease. We aimed to investigate the subclinical systolic ventricular dysfunction of patients with OSA using novel speckle tracking echocardiographic (STE) techniques. METHODS: This study included 31 patients of polysomnography proven very severe OSA [Apnea Hypopnea Index(AHI) >40] and an equal number of matched population with no OSA as controls...
May 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28648251/immune-thrombocytopenia-of-childhood-responsive-to-tonsillectomy-in-the-setting-of-chronic-tonsillitis-a-case-report-and-literature-review
#5
Richard William Thompson, Anil Gungor
OBJECTIVES: Immune thrombocytopenia of childhood (platelet count <100,000/μL) is the most common cause of thrombocytopenia in children. Patients typically present with bruising and bleeding in the setting of thrombocytopenia. Although it is usually short-lived, some cases persist and are unresponsive to treatment. This can lead to exposure to a variety of treatment regimens including immunosuppressants and splenectomy. The goal of this report is to present a case of chronic ITP of childhood that responded to tonsillectomy addressing the tonsils as a source of chronic infection and inflammation triggering ITP...
November 23, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28647854/the-influence-of-head-of-bed-elevation-in-patients-with-obstructive-sleep-apnea
#6
Fábio José Fabrício de Barros Souza, Pedro Rodrigues Genta, Albino José de Souza Filho, Andrew Wellman, Geraldo Lorenzi-Filho
PURPOSE: The purpose of this study is to test the effects of a mild degree of head-of-bed elevation (HOBE) (7.5°) on obstructive sleep apnea (OSA) severity and sleep quality. METHODS: OSA patients were recruited from a single sleep clinic (Criciúma, Santa Catarina, Brazil). Following a baseline polysomnography (PSG), all patients underwent a PSG with HOBE (within 2 weeks). In addition, a subset of patients performed a third PSG without HOBE. RESULTS: Fifty-two patients were included in the study (age 53...
June 24, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28647595/intermittent-hypoxia-caused-cognitive-dysfunction-relate-to-mirnas-dysregulation-in-hippocampus
#7
Huabin Gao, Zhaoli Han, Shan Huang, Ruojing Bai, Xintong Ge, Fanglian Chen, Ping Lei
Intermittent hypoxia (IH) is a characteristic pathophysiological change of obstructive sleep apnea (OSA), a commonly diagnosed chronic sleep disorder. With the process of OSA, patients will suffer from the nervous system damage and appear to multiple cognitive dysfunction. The mechanism that how IH causes cognitive impairment is still unknown. Both control and experimental rats were placed in conditions absence and presence of intermittent hypoxia (IH) for 8h a day for a week, two weeks and four weeks, and then followed by behavioral assessments with Morris Water Maze (MWM) test...
June 21, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28647143/a-tertiary-center-experience-with-velopharyngeal-surgical-techniques-for-treatment-of-snoring-and-obstructive-sleep-apnea
#8
Omer Karakoc, Murat Binar, Umit Aydin, Hakan Genc, Timur Akcam, Mustafa Gerek
OBJECTIVES: The aim of this study was to assess the outcomes of patients who treated with the relatively new surgical procedures; anterior palatoplasty (AP), Cahali lateral pharyngoplasty (CLP), and expansion sphincter pharyngoplasty (ESP) for habitual snoring or obstructive sleep apnea (OSA). METHODS: Prospective series of 93 patients were evaluated. The performed surgical techniques, polysomnographic outcomes, pre- and postoperative clinical parameters, and complication rates were assessed...
June 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28646811/alternative-therapy-for-patients-with-obstructive-sleep-apnea-hypopnea-syndrome-a-1-year-single-blind-randomized-trial-of-tui-na
#9
Cheng-Nan Lu, Michael Friedman, Hsin-Ching Lin, Kuo-Wei Bi, Tun-Pin Hsueh, Hsueh-Wen Chang, Mao-Chang Su, Meng-Chih Lin
Context • Obstructive sleep apnea/hypopnea syndrome (OSAHS) is among the most prevalent of sleep-related breathing disorders. No long-term follow-up studies have documented the continued success of lifestyle changes in treatment; oral appliances have an approximate 50% success rate; compliance with continuous positive airway pressure is poor, ranging from 50% to 89%; and the success rate of upper-airway surgery is only 66.4%. Therefore, some OSAHS patients seek alternative treatments. Objectives • The study intended to examine the efficacy of traditional Chinese therapeutic massage (tui na) for patients with OSAHS...
July 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28645668/titration-technique-using-endoscopy-for-an-oral-appliance-treatment-of-obstructive-sleep-apnea
#10
Kentaro Okuno, Kazuki Ikai, Erika Matsumura-Ai, Takafumi Araie
The degree of mandibular protrusion for an oral appliance (OA) should be customized for each patient with obstructive sleep apnea (OSA). This article describes the mandibular titration technique for OAs to effectively treat OSA by using endoscopy to evaluate the change in the airway at the velopharynx. This technique may minimize the degree of mandible protrusion and contribute to both the efficacy of and compliance with OA therapy.
June 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28645471/association-of-obstructive-sleep-apnea-with-subclinical-cardiovascular-disease-predicted-by-coronary-artery-calcium-score-in-asymptomatic-subjects
#11
Min Young Seo, Jin-Young Lee, Joo-Yong Hahn, Gwanghui Ryu, Sang Duk Hong, Hun-Jong Dhong, Seung-Kyu Chung, Hyo Yeol Kim
The aim of this study is to determine the association among various sleep parameters for obstructive sleep apnea (OSA) and subclinical cardiovascular disease measured by coronary artery calcium (CAC) score. A cross-sectional study was conducted among 461 patients who underwent both polysomnography (PSG) and coronary artery computed tomography to evaluate CAC score. For each participant, coronary artery computed tomography was conducted within 12 months of PSG. We evaluated the possible association among various PSG parameters by evaluating overnight-attended PSG and CAC...
May 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28645463/etiologies-of-chronic-cough-in-pediatric-cohorts-chest-guideline-and-expert-panel-report
#12
Anne B Chang, John J Oppenheimer, Miles Weinberger, Cameron C Grant, Bruce K Rubin, Richard S Irwin
BACKGROUND: In children (aged ≤14-years) there is no published systematic review on the etiologies of chronic cough or, the relationship between obstructive sleep apnea (OSA) and chronic cough. We thus undertook systematic reviews based on key questions (KQs) using the PICO format. The KQs were: Among children with chronic (>4 weeks) cough: (1) are the common etiologies different from adults? (2) are the common etiologies age and/or setting dependent? and; (3) is obstructive sleep apnea (OSA) an etiology of chronic cough in children? METHODS: We used the CHEST expert cough panel's protocol and the American College of Chest Physicians (CHEST) methodological guidelines and GRADE framework...
June 20, 2017: Chest
https://www.readbyqxmd.com/read/28645317/facial-soft-tissue-response-to-maxillo-mandibular-advancement-in-obstructive-sleep-apnea-syndrome-patients
#13
Julio Cifuentes, Christian Teuber, Alfredo Gantz, Ariel Barrera, Gholamreza Danesh, Nicolas Yanine, Carsten Lippold
No abstract text is available yet for this article.
June 23, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/28643675/-stop-bang-a-useful-and-easy-tool-for-the-screening-of-obstructive-sleep-apnea
#14
Matías Baldini, María Nélida Chiapella, María Alejandra Fernández, Sergio Guardia
The STO-BANG questionnaire, S standing for snore, T tired, O observed apneas, P pressure (arterial hypertension), B BMI (body mass index > 35 kg/ m2), A age (> 50 years old), N neck circumference (> 40 cm), G gender (male); is a simple tool that enables the detection of patients with obstructive sleep apnea syndrome (OSA). If the patient adds 3 or more points, it is considered to have a high probability of having this disease. Our goal was to evaluate the capacity of the STOP-BANG questionnaire and to compare it with the ability of a sleep trained pulmonologist in determining the probability of OSA...
2017: Medicina
https://www.readbyqxmd.com/read/28643476/low-leptin-concentration-may-identify-heart-failure-patients-with-central-sleep-apnea
#15
Ivan Cundrle, Virend K Somers, Prachi Singh, Bruce D Johnson, Christopher G Scott, Lyle J Olson
Low leptin concentration has been shown to be associated with central sleep apnea in heart failure patients. We hypothesized that low leptin concentration predicts central sleep apnea. Consecutive ambulatory New York Heart Association (NYHA) classes I-IV heart failure patients were studied prospectively, including measurement of serum leptin, echocardiography and polysomnography. Sleep apnea was defined by type (central/mixed/obstructive) and by apnea-hypopnea index ≥5 by polysomnography. Subjects were divided into four groups by polysomnography: (1) central sleep apnea, (2) mixed apnea, (3) no apnea and (4) obstructive sleep apnea...
June 23, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28642543/association-of-obstructive-sleep-apnea-with-asthma-a-meta-analysis
#16
De-Lei Kong, Zheng Qin, Hui Shen, Hong-Yu Jin, Wei Wang, Zan-Feng Wang
This study evaluates the relationship between obstructive sleep apnea (OSA) and asthma. Literature search was carried out in several electronic databases and random effects meta-analyses were performed to obtain pooled estimates of the prevalence of OSA, OSA risk and sleep disordered breathing (SDB) in asthma patients and pooled odds ratios of the prevalence between asthma and non-asthma patients. In adult asthma patients, the prevalence [95% confidence interval] of OSA, OSA risk, and SDB was 49.50 [36.39, 62...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28642292/frequency-and-magnitude-of-intermittent-hypoxia-modulate-endothelial-wound-healing-in-a-cell-culture-model-of-sleep-apnea
#17
Noelia Campillo, Bryan Falcones, Josep M Montserrat, David Gozal, Ana Obeso, Teresa Gallego-Martin, Daniel Navajas, Isaac Almendros, Ramon Farre
Intermittent hypoxia (IH) has been implicated in the cardiovascular consequences of obstructive sleep apnea (OSA). However, the lack of suitable experimental systems has precluded assessment as to whether IH is detrimental, protective or both for the endothelium. The aim of the work was to determine the effects of frequency and amplitude of IH oxygenation swings on aortic endothelial wound healing. Monolayers of human primary endothelial cells were wounded, and subjected to constant oxygenation (1%, 4%, 13% or 20% O2) or IH at different frequencies (0...
June 22, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28640657/retinal-findings-on-oct-in-systemic-conditions
#18
Preeti Patil Chhablani, Vikas Ambiya, Akshay G Nair, Sailaja Bondalapati, Jay Chhablani
PURPOSE: Imaging technology has advanced by leaps and bounds in the recent past and has resulted in a much greater understanding of ocular diseases. The aim of this review article is to summarize optical coherence tomography (OCT) findings of various systemic conditions. METHOD: A systematic literature search of the Medline/PubMed database was performed. English articles up to April 2015 were included. Terms used for search included: Alzheimer's Disease; Multiple Sclerosis; Parkinson's Disease; Behçet's Disease; Schizophrenia; Migraine; Obstructive Sleep Apnea Syndrome; Neurofibromatosis; Sickle Cell Disease; Renal diseases; Lupus Retinopathy; Valsalva Retinopathy; Whiplash Retinopathy; Shaken-Baby Syndrome; Choroidal metastases; Intracranial Hypertension; Drug toxicity; Deferoxamine; Sildenafil; Tamoxifen; Hydroxychloroquine; Chloroquine; Ethambutol; Lead; Sickle Cell Disease; and Thalassemia along with OCT...
June 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28639773/-paradigm-shift-in-the-treatment-of-atrial-fibrillation-the-importance-of-risk-factor-management
#19
Stefania Aur, Patrizio Pascale
The prevalence of atrial fibrillation (AF) is constantly rising. Different studies have underlined the correlation between AF and modifiable risk factors such as obesity, obstructive sleep apnea, hypertension and sedentary lifestyle. Treatment of these comorbidities could significantly reduce the AF burden and the recurrence rate after cardioversion or ablation. These data should therefore lead to a paradigm shift in the management of AF. A strategy limited to catheter ablation or to the prescription of an antiarrhythmic drug is not sufficient...
May 24, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28639573/a-transcriptomic-analysis-of-physiological-significance-of-hypoxia-inducible-factor-1%C3%AE-in-myogenesis-and-carbohydrate-metabolism-of-genioglossus-in-mice
#20
Tong Hao, Yue-Hua Liu, Yuan-Yuan Li, Yun Lu, Hong-Yi Xu
BACKGROUND: Chronic intermittent hypoxia is the most remarkable feature of obstructive sleep apnea/hypopnea syndrome and it can induce the change of hypoxia-inducible factor-1α (HIF-1α) expression and contractile properties in the genioglossus. To clarify the role of HIF-1α in contractile properties of the genioglossus, this study generated and compared high-throughput RNA-sequencing data from genioglossus between HIF-1α conditional knockout (KO) mice and littermate wild-type (WT) mice...
July 5, 2017: Chinese Medical Journal
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