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https://www.readbyqxmd.com/read/27900664/improvement-production-of-hyaluronic-acid-by-streptococcus-zooepidemicus-in-sugarcane-molasses
#1
Nicole Caldas Pan, Hanny Cristina Braga Pereira, Maria de Lourdes Corradi da Silva, Ana Flora Dalberto Vasconcelos, Maria Antonia Pedrine Colabone Celligoi
Microbial hyaluronic acid (HA) production has been preferred rather than extraction from animal tissue for medical and cosmetic applications. In this context, to obtain an economically competitive HA production by Streptococcus zooepidemicus, culture conditions were studied to improve the polymer production in sugarcane molasses. The highest HA production by S. zooepidemicus ATCC 39920 achieved was 2.825 g. L(-1) in a 4.5 L bioreactor with controlled pH (8.0) and medium containing molasses (85.35 g.L(-1) total sugar) pretreated with activated charcoal and yeast extract (50 g...
November 30, 2016: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/27871322/causes-of-maternal-and-child-mortality-among-cambodian-sex-workers-and-their-children-a-cross-sectional-study
#2
Brian Willis, Saki Onda, Hanni Marie Stoklosa
BACKGROUND: To reach global and national goals for maternal and child mortality, countries must identify vulnerable populations, which includes sex workers and their children. The objective of this study was to identify and describe maternal deaths of female sex workers in Cambodia and causes of death among their children. METHODS: A convenience sample of female sex workers were recruited by local NGOs that provide support to sex workers. We modified the maternal mortality section of the 2010 Cambodia Demographic and Health Survey and collected reports of all deaths of female sex workers...
November 21, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27868158/growth-and-prevalence-of-feeding-difficulties-in-children-with-robin-sequence-a-retrospective-cohort-study
#3
Emma C Paes, Iris A C de Vries, Wouter M Penris, Karlijn H Hanny, Selma W Lavrijsen, Elselien K van Leerdam, Maaike M Rademaker, Esther S Veldhoen, Rene M J C Eijkemans, Moshe Kon, Corstiaan C Breugem
OBJECTIVES: In addition to breathing problems, patients with Robin sequence (RS) often encounter feeding difficulties (FD). Data regarding the occurrence of FD and possible influencing factors are scarce. The study aim was to elucidate these factors to improve treatment strategies. MATERIAL AND METHODS: A retrospective comparative cohort study was conducted, consisting of 69 infants diagnosed with both RS and a cleft palate and 64 isolated cleft palate only (iCPO) infants...
November 21, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27833456/the-impact-of-caregiver-treatment-satisfaction-upon-child-and-parent-outcomes
#4
Mary Acri, Lindsay A Bornheimer, Lauren Jessell, Hanni B Flaherty, Mary M McKay
BACKGROUND: Parental perceptions about treatment influence their child's engagement in and ongoing utilization of mental health services, but less is known about the association between caregiver expectancies and family outcomes. The literature is particularly lacking with families of color, who are at high risk for the onset and perpetuation of disruptive behaviors. METHODS: The purpose of this study was to examine caregiver treatment satisfaction amongst 320 youth of color aged 7 to 11 and their families who were assigned to either a Multiple Family Group intervention or services as usual condition...
November 2016: Child and Adolescent Mental Health
https://www.readbyqxmd.com/read/27827534/correlates-of-sleep-disturbances-in-depressed-older-persons-the-netherlands-study-of-depression-in-older-persons-nesdo
#5
Rian Johanna Gerdina Peters van Neijenhof, Erik van Duijn, Hannie C Comijs, Julia F van den Berg, Margot W M de Waal, Richard C Oude Voshaar, Roos C van der Mast
OBJECTIVES: Sleep disturbances are common among depressed older persons. To gain insight into sleep disturbances in late-life depression, their occurrence and correlates were assessed. METHODS: Baseline data of 294 depressed older persons of the Netherlands Study of Depression in Older persons study were used. A diagnosis of current depression according to the diagnostic and statistical manual of mental disorders-IV (DSM-IV) was assessed with the Composite International Diagnostic Interview...
November 9, 2016: Aging & Mental Health
https://www.readbyqxmd.com/read/27802265/antisense-oligonucleotide-based-splice-correction-for-ush2a-associated-retinal-degeneration-caused-by-a-frequent-deep-intronic-mutation
#6
Radulfus Wn Slijkerman, Christel Vaché, Margo Dona, Gema García-García, Mireille Claustres, Lisette Hetterschijt, Theo A Peters, Bas P Hartel, Ronald Je Pennings, José M Millan, Elena Aller, Alejandro Garanto, Rob Wj Collin, Hannie Kremer, Anne-Françoise Roux, Erwin Van Wijk
Usher syndrome (USH) is the most common cause of combined deaf-blindness in man. The hearing loss can be partly compensated by providing patients with hearing aids or cochlear implants, but the loss of vision is currently untreatable. In general, mutations in the USH2A gene are the most frequent cause of USH explaining up to 50% of all patients worldwide. The first deep-intronic mutation in the USH2A gene (c.7595-2144A>G) was reported in 2012, leading to the insertion of a pseudoexon (PE40) into the mature USH2A transcript...
November 1, 2016: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/27800086/snakebite-in-bedroom-kills-a-physician-in-cameroon-a-case-report
#7
Armand Nkwescheu, Leopold Cyriaque Donfack Mbasso, Franky Baonga Ba Pouth, Anastase Dzudie, Serge Clotaire Billong, Hermann Ngouakam, Joseph Le Doux Diffo, Hanny Eyongorock, Wilfred Mbacham
The World Health Organization (WHO) classifies snake bites as neglected public health problem affecting mostly tropical and subtropical countries. In Africa there are an estimated 1 million snake bites annually with about half needing a specific treatment. Women, children and farmers in poor rural communities in developing countries are the most affected. Case management of snake bites are not adequate in many health facilities in developing countries where personnel are not always abreast with the new developments in snake bite management and in addition, quite often the anti-venom serum is lacking...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27771245/early-and-late-onset-depression-in-late-life-a-prospective-study-on-clinical-and-structural-brain-characteristics-and-response-to-electroconvulsive-therapy
#8
Annemiek Dols, Filip Bouckaert, Pascal Sienaert, Didi Rhebergen, Kristof Vansteelandt, Mara Ten Kate, Francois-Laurent de Winter, Hannie C Comijs, Louise Emsell, Mardien L Oudega, Eric van Exel, Sigfried Schouws, Jasmien Obbels, Mike Wattjes, Frederik Barkhof, Piet Eikelenboom, Mathieu Vanderbulcke, Max L Stek
OBJECTIVE: The clinical profile of late-life depression (LLD) is frequently associated with cognitive impairment, aging-related brain changes, and somatic comorbidity. This two-site naturalistic longitudinal study aimed to explore differences in clinical and brain characteristics and response to electroconvulsive therapy (ECT) in early- (EOD) versus late-onset (LOD) late-life depression (respectively onset <55 and ≥55 years). METHODS: Between January 2011 and December 2013, 110 patients aged 55 years and older with ECT-treated unipolar depression were included in The Mood Disorders in Elderly treated with ECT study...
September 22, 2016: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27764950/experiences-of-vision-impairment-in-papua-new-guinea-implications-for-blindness-prevention-programs
#9
Anthea Burnett, Aryati Yashadhana, Maria Cabrera Aguas, Yvonne Hanni, Mitasha Yu
INTRODUCTION: A person's capability to access services and achieve good eye health is influenced by their behaviours, perceptions, beliefs and experiences. As evidence from Papua New Guinea (PNG) about people's lived experience with vision impairment is limited, the purpose of the present study was to better understand the beliefs, perceptions and emotional responses to vision impairment in PNG. METHODS: A qualitative study, using both purposive and convenience sampling, was undertaken to explore common beliefs and perceptions about vision impairment, as well as the emotional responses to vision impairment...
October 2016: Rural and Remote Health
https://www.readbyqxmd.com/read/27740642/scarring-of-soft-tissues-following-apical-surgery-visual-assessment-of-outcomes-one-year-after-intervention-using-the-bern-and-manchester-scores
#10
Thomas von Arx, Simone Fm Janner, Stefan Hänni, Michael M Bornstein
The successful outcome of apical surgery is usually defined by absence of clinical signs and symptoms and resolution of previous periapical radiolucencies. However, little attention is given to soft tissue scarring. The present study evaluated the severity of gingival and mucosal scarring 1 year following apical surgery of 52 teeth. Clinical pictures taken at the 1-year examination were rated by three observers using specific scarring scores. The overall repeatability of the two scores was high (85.3%), whereas the overall reproducibility was relatively low (44...
November 2016: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/27730226/high-internal-phase-emulsions-stabilized-solely-by-whey-protein-isolate-low-methoxyl-pectin-complexes-effect-of-ph-and-polymer-concentration
#11
Wahyu Wijaya, Paul Van der Meeren, Christofora Hanny Wijaya, Ashok R Patel
In recent years, there has been significant progress in edible emulsion technology especially with respect to creating and stabilizing surfactant-free emulsion systems for food applications. In this paper, we demonstrate the fabrication of high internal phase emulsions (HIPE) (φoil = 0.82) stabilized using colloidal complexes of non-gelling biopolymers (at concentrations as low as 0.3 wt%). The colloidal complexes were pre-formed by combining whey protein isolate (WPI) and low-methoxyl pectin (LMP) at three different pH values (i...
October 12, 2016: Food & Function
https://www.readbyqxmd.com/read/27694370/cohort-differences-in-cognitive-aging-in-the-longitudinal-aging-study-amsterdam
#12
Anamaria Brailean, Martijn Huisman, Martin Prince, A Matthew Prina, Dorly J H Deeg, Hannie Comijs
OBJECTIVES: This study aims to examine cohort differences in cognitive performance and rates of change in episodic memory, processing speed, inductive reasoning, and general cognitive performance and to investigate whether these cohort effects may be accounted for by education attainment. METHOD: The first cohort (N = 705) was born between 1920 and 1930, whereas the second cohort (N = 646) was born between 1931 and 1941. Both birth cohorts were aged 65 to 75 years at baseline and were followed up 3 and 6 years later...
September 30, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/27672647/unique-case-of-oligoastrocytoma-with-recurrence-and-grade-progression-exhibiting-differential-expression-of-high-mobility-group-a1-and-human-telomerase-reverse-transcriptase
#13
Puneet Gandhi, Richa Khare, Kavita Niraj, Nitin Garg, Sandeep K Sorte, Hanni Gulwani
Mixed gliomas, primarily oligoastrocytomas, account for about 5%-10% of all gliomas. Distinguishing oligoastrocytoma based on histological features alone has limitations in predicting the exact biological behavior, necessitating ancillary markers for greater specificity. In this case report, human telomerase reverse transcriptase (hTERT) and high mobility group-A1 (HMGA1); markers of proliferation and stemness, have been quantitatively analyzed in formalin-fixed paraffin-embedded tissue samples of a 34 years old patient with oligoastrocytoma...
September 16, 2016: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/27670933/referral-patterns-of-special-needs-patients-at-the-royal-dental-hospital-of-melbourne-victoria-australia
#14
Maryani Mohamed Rohani, Hanny Calache, Mina Borromeo
BACKGROUND: Special Needs Dentistry (SND) has been recognised as a dental specialty in Australia since 2003 but no studies addressing the profile of patients for specialist care. The purpose of this study is to identify, via referrals received, the profile of patients and quality of referrals at the largest public SND Unit in Victoria, Australia. METHODS: All referrals received over a six months period (January 1 - June 30, 2013) by the Integrated SND Unit (ISNU) were reviewed prior to allocation to the outpatient clinic (OP), domiciliary (DOM) or general anaesthetic (GA) services...
September 27, 2016: Australian Dental Journal
https://www.readbyqxmd.com/read/27630553/perceptual-and-social-attributes-underlining-age-related-preferences-for-faces
#15
Hanni S M Kiiski, Brendan Cullen, Sarah L Clavin, Fiona N Newell
Although aesthetic preferences are known to be important in person perception and can play a significant role in everyday social decisions, the effect of the age of the observer on aesthetic preferences for faces of different ages has not yet been fully investigated. In the present study we investigated whether aesthetic preferences change with aging, with an age-related bias in favoring faces from one's own age group. In addition, we examined the role of age on both the perceptual qualities and the social attributes of faces that may influence these aesthetic judgements...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27629283/community-based-population-level-interventions-for-promoting-child-oral-health
#16
Andrea M de Silva, Shalika Hegde, Bridget Akudo Nwagbara, Hanny Calache, Mark G Gussy, Mona Nasser, Hannah R Morrice, Elisha Riggs, Pamela M Leong, Lisa K Meyenn, Reza Yousefi-Nooraie
BACKGROUND: Dental caries and gingival and periodontal disease are commonly occurring, preventable chronic conditions. Even though much is known about how to treat oral disease, currently we do not know which community-based population-level interventions are most effective and equitable in preventing poor oral health. OBJECTIVES: Primary • To determine the effectiveness of community-based population-level oral health promotion interventions in preventing dental caries and gingival and periodontal disease among children from birth to 18 years of age...
September 15, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27626625/renal-interstitial-fibrosis-an-imperfect-predictor-of-kidney-disease-progression-in-some-patient-cohorts
#17
Hanni Menn-Josephy, Carol S Lee, Angela Nolin, Marta Christov, Denis V Rybin, Janice M Weinberg, Joel Henderson, Ramon Bonegio, Andrea Havasi
BACKGROUND: The extent of interstitial fibrosis on kidney biopsy is regarded as a prognostic indicator and guide to treatment. Patients with extensive fibrosis are assigned to supportive treatments with the expectation that they have advanced beyond the point at which immunosuppressive or other disease-modifying therapies would be of benefit. Our study highlights some of the limitations of using interstitial fibrosis to predict who will develop end-stage renal disease (ESRD). METHODS: Analysis of 434 consecutive renal biopsies performed between 2001 and 2012 at a single center...
2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27588732/episodic-memory-function-is-affected-by-lifestyle-factors-a-14-year-follow-up-study-in-an-elderly-population
#18
Ruth Klaming, Jacopo Annese, Dick J Veltman, Hannie C Comijs
Understanding the relationship between memory function and lifestyle offers great opportunities for promoting beneficial lifestyle choices to foster healthy cognitive aging and for the development of intervention programs for older adults. We studied a cohort of older adults (age 65 and older) enrolled in the Longitudinal Aging Study Amsterdam, an ongoing prospective population-based research project. A total of 1,966 men and women participated in an episodic memory test every 3 years over a period of 14 years...
September 2, 2016: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/27566820/clec12a-mediated-antigen-uptake-and-cross-presentation-by-human-dendritic-cell-subsets-efficiently-boost-tumor-reactive-t-cell-responses
#19
Tim J A Hutten, Soley Thordardottir, Hanny Fredrix, Lisanne Janssen, Rob Woestenenk, Jurjen Tel, Ben Joosten, Alessandra Cambi, Mirjam H M Heemskerk, Gerben M Franssen, Otto C Boerman, Lex B H Bakker, Joop H Jansen, Nicolaas Schaap, Harry Dolstra, Willemijn Hobo
Potent immunotherapies are urgently needed to boost antitumor immunity and control disease in cancer patients. As dendritic cells (DCs) are the most powerful APCs, they are an attractive means to reinvigorate T cell responses. An appealing strategy to use the effective Ag processing and presentation machinery, T cell stimulation and cross-talk capacity of natural DC subsets is in vivo tumor Ag delivery. In this context, endocytic C-type lectin receptors are attractive targeting molecules. In this study, we investigated whether CLEC12A efficiently delivers tumor Ags into human DC subsets, facilitating effective induction of CD4(+) and CD8(+) T cell responses...
October 1, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27544533/the-longitudinal-aging-study-amsterdam-cohort-update-2016-and-major-findings
#20
Emiel O Hoogendijk, Dorly J H Deeg, Jan Poppelaars, Marleen van der Horst, Marjolein I Broese van Groenou, Hannie C Comijs, H Roeline W Pasman, Natasja M van Schoor, Bianca Suanet, Fleur Thomése, Theo G van Tilburg, Marjolein Visser, Martijn Huisman
The Longitudinal Aging Study Amsterdam (LASA) is an ongoing longitudinal study of older adults in the Netherlands, which started in 1992. LASA is focused on the determinants, trajectories and consequences of physical, cognitive, emotional and social functioning. The study is based on a nationally representative sample of older adults aged 55 years and over. The findings of the LASA study have been reported in over 450 publications so far (see www.lasa-vu.nl ). In this article we describe the background and the design of the LASA study, and provide an update of the methods...
September 2016: European Journal of Epidemiology
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