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https://www.readbyqxmd.com/read/28418079/loneliness-and-cardiovascular-disease-and-the-role-of-late-life-depression
#1
Annette Hegeman, Natasja Schutter, Hannie Comijs, Tjalling Holwerda, Jack Dekker, Max Stek, Roos van der Mast
OBJECTIVE: Loneliness and depression have a strong reciprocal influence, and both predict adverse health outcomes at old age. Therefore, this study examines whether loneliness is associated with the presence of cardiovascular diseases taking into account the role of late-life depression. METHODS: Cross-sectional data of 477 older adults in the Netherlands Study of Depressed Older Persons were used. Logistic regression analysis was performed to examine the relation between loneliness and cardiovascular disease...
April 18, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28391908/apob-lipoproteins-and-dysfunctional-white-adipose-tissue-relation-to-risk-factors-for-type-2-diabetes-in-humans
#2
Valérie Lamantia, Simon Bissonnette, Hanny Wassef, Yannick Cyr, Alexis Baass, Robert Dufour, Rémi Rabasa-Lhoret, May Faraj
BACKGROUND: Elevated plasma apoB is an independent predictor of T2D; however, underlying mechanisms remain unclear. Chronic reduction in white adipose tissue (WAT) function promotes T2D. We reported that differentiation of preadipocytes and acute incubation of human WAT with LDL induce their dysfunction (decreased hydrolysis and storage of triglyceride-rich lipoproteins [TRL]). OBJECTIVE: To examine the hypothesis that the association of plasma apoB with T2D risk factors, hypertriglyceridemia (hyperTG), insulin resistance (IR), and hyperinsulinemia, was dependent on WAT dysfunction...
January 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28380722/effects-of-a-savoring-intervention-on-resilience-and-well-being-of-older-adults
#3
Jennifer L Smith, Agnieszka A Hanni
Savoring is the ability to be mindful of positive experiences and to be aware of and regulate positive feelings about these experiences. Previous research has found that savoring interventions can be effective at improving well-being of younger adults, but findings have not been extended to older populations. This pilot study examined the effects of a 1-week savoring intervention on older adults' psychological resilience and well-being (i.e., depressive symptoms and happiness). Participants, 111 adults ages 60 or over, completed measures of resilience, depressive symptoms, and happiness pre- and postintervention as well as 1 month and 3 months after the intervention...
February 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28368522/premature-ovarian-insufficiency-phenotypic-characterization-within-different-etiologies
#4
Xue Jiao, Huihui Zhang, Hanni Ke, Jiangtao Zhang, Lei Cheng, Yixun Liu, Yingying Qin, Zi-Jiang Chen
Context: Premature ovarian insufficiency (POI) is highly heterogeneous, both in phenotype and etiology. They are not yet clearly stated and correlated. Objective: To characterize clinical presentations of a large, well-phenotyped cohort of women with POI, and correlate phenotypes with etiologies to draw a comprehensive clinical picture of POI. Design, Patients, Interventions and Main Outcome Measures: In this retrospective study, a total of 955 Chinese women with overt POI between 2006 and 2015 were systemically evaluated and analyzed...
March 28, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28356429/enrichment-of-triglyceride-rich-lipoproteins-with-apolipoprotein-c-i-is-positively-associated-with-their-delayed-plasma-clearance-independently-of-other-transferable-apolipoproteins-in-postmenopausal-overweight-and-obese-women
#5
Hanny Wassef, Simon Bissonnette, Robert Dufour, Jean Davignon, May Faraj
Background: The role of plasma apolipoprotein (apo) C-I in cardiometabolic risk in humans is unclear. However, in vitro studies showed a dual role for apoC-I, both protective and harmful, depending on the carrier lipoprotein.Objective: We tested the hypothesis that triglyceride (TG)-rich lipoprotein (TRL) apoC-I, not total or HDL apoC-I, is associated with delayed postprandial plasma clearance of TRLs, independently of apoC-II, apoC-III, and apoE.Methods: This cross-sectional study examines the plasma clearance of a (13)C-triolein-labeled high-fat meal (68% fat energy) in 20 postmenopausal overweight and obese women [body mass index (in kg/m(2)) ≥27; aged 45-74 y] as the increment change in area under the 6-h postprandial curves (iAUC6h) of TRL parameters...
March 29, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28352621/granulomatous-prostatitis-clinical-and-histomorphologic-survey-of-the-disease-in-a-tertiary-care-hospital
#6
Prakriti Shukla, Hanni V Gulwani, Sukhpreet Kaur
BACKGROUND: Granulomatous prostatitis is an uncommon entity that is diagnosed incidentally on histopathology and is broadly classified as nonspecific, specific, postsurgical (post-transurethral resection), or secondary to other rare systemic granulomatous diseases. Only very few studies are available in the literature that describe the clinical and histomorphological spectrum of the disease. METHODS: A retrospective analysis of histopathological records of 1,181 prostatic specimens received in the pathology department was done over a period of 13 years (January 2003 to January 2016)...
March 2017: Prostate International
https://www.readbyqxmd.com/read/28348495/role-of-illness-perception-and-self-efficacy-in-lifestyle-modification-among-non-alcoholic-fatty-liver-disease-patients
#7
Shira Zelber-Sagi, Shiran Bord, Gali Dror-Lavi, Matthew Lee Smith, Samuel D Towne, Assaf Buch, Muriel Webb, Hanny Yeshua, Assy Nimer, Oren Shibolet
AIM: To describe the relationships between non-alcoholic fatty-liver disease (NAFLD) patient's disease consequences and treatment perceptions, self-efficacy, and healthy lifestyle maintenance. METHODS: A cross-sectional study among 146 ultrasound diagnosed NAFLD patients who visited the fatty liver clinic at the Tel-Aviv Medical Center. Eighty-seven of these individuals, participated in a clinical trial of physical activity and underwent fasting blood tests, analyzed at the same lab...
March 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28345485/the-effect-of-tamoxifen-on-thin-endometrium-in-patients-undergoing-frozen-thawed-embryo-transfer
#8
Hanni Ke, Jingjing Jiang, Mingdi Xia, Rong Tang, Yingying Qin, Zi-Jiang Chen
Tamoxifen has played a vital role in endocrine therapy for the treatment of estrogen receptor-positive breast cancer. We examined the effect of tamoxifen in patients with a thin endometrium in frozen-thawed embryo transfer (FET) cycles and compared the improvement in endometrial thickness (EMT) and pregnancy outcomes stratified by different etiologies of thin endometrium. A total of 226 women were recruited for a new tamoxifen protocol; all had an EMT of less than 7.5 mm in previous cycles, including natural cycle (NC), hormone replacement treatment (HRT), and ovulation induction (OI) cycles...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28276251/burden-on-caregivers-of-older-patients-with-bipolar-disorder
#9
Annemiek Dols, Carisha Thesing, Martijn Wouters, Jan Theunissen, Caroline Sonnenberg, Hannie Comijs, Max L Stek
OBJECTIVES: Available data suggest high burden on caregivers of patientswith bipolar disorder (BD), yet the well-being of patients with BD increasingly depends on family members, partners and close friends. Aspatients with BD get older, the need for informal care may shift. We aimed to describe the caregivers of older adults with BD (OABD) and explore what patients' and caregivers' characteristics are associated with caregiver burden. METHOD: Forty-seven caregivers of OABD were questioned about their perceived burden and depressive symptoms...
March 9, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28271515/a-cross-sectional-and-longitudinal-study-of-endodontic-and-periapical-status-in-an-australian-population
#10
Aovana Timmerman, Hanny Calache, Peter Parashos
BACKGROUND: This study described the cross-sectional and longitudinal data of endodontic and periapical status of new patients presenting to a major dental hospital, and assessed the relationships between tooth-related variables with apical periodontitis. METHODS: The records of 695 patients were randomly selected and the orthopantomograms of these patients up to 31(st) October 2014 were reviewed by two endodontists. The periapical status of teeth was recorded using the Periapical Index...
March 8, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28260548/efficacy-of-fibre-additions-to-flatbread-flour-mixes-for-reducing-post-meal-glucose-and-insulin-responses-in-healthy-indian-subjects
#11
Hanny M Boers, Katrina MacAulay, Peter Murray, Rajendra Dobriyal, David J Mela, Maria A M Spreeuwenberg
The incidence of type 2 diabetes mellitus (T2DM) is increasing worldwide, including in developing countries, particularly in South Asia. Intakes of foods generating a high postprandial glucose (PPG) response have been positively associated with T2DM. As part of efforts to identify effective and feasible strategies to reduce the glycaemic impact of carbohydrate-rich staples, we previously found that addition of guar gum (GG) and chickpea flour (CPF) to wheat flour could significantly reduce the PPG response to flatbread products...
February 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28215902/childhood-abuse-and-the-two-year-course-of-late-life-depression
#12
Ilse Wielaard, Hannie C Comijs, Max L Stek, Didi Rhebergen
OBJECTIVES: Late-life depression often has a chronic course, with debilitating effects on functioning and quality of life; there is still no consensus on important risk factors explaining this chronicity. Cross-sectional studies have shown that childhood abuse is associated with late-life depression, and in longitudinal studies with chronicity of depression in younger adults. We aim to investigate the impact of childhood abuse on the course of late-life depression. DESIGN: Two-year longitudinal cohort study...
January 24, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28203389/mr-appearance-of-the-temporal-evolution-and-resolution-of-spontaneous-osteonecrosis-of-the-knee-a-case-report
#13
Mats Geijer, Jan Jureus, Mari Hanni, Adel Shalabi
Spontaneous osteonecrosis of the knee (SONK) is a feared condition of unknown cause, in its classic form appearing in the medial femoral condyle in middle-aged or elderly subjects. Diagnosis with radiography is notoriously difficult with a long latency before typical changes appear. Magnetic resonance imaging (MRI) is regarded as a diagnostic tool with the possibility to give an earlier diagnosis with improved chances for treatment. However, also with MRI there may be an initial diagnostic blind spot before typical changes appear...
February 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28198344/-a-woman-with-reversible-encephalopathy
#14
E M Boot, K H Hanny, F J A Meijer, J J J van Eijk
A 72-year-old woman who recently had been treated with metronidazole presented with subacute dysarthria, gait ataxia and encephalopathy with severe anxiety. Head MRI showed symmetrical T2-hyperintensities. Under suspicion of a metronidazole-induced encephalopathy, metronidazole was stopped immediately. The patient recovered completely and follow-up MRI showed complete resolution of T2-hyperintensities.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28179090/protective-role-of-soluble-receptor-for-advanced-glycation-end-products-in-patients-with-non-alcoholic-fatty-liver-disease
#15
Shira Zelber-Sagi, Federico Salomone, Ilana Kolodkin-Gal, Noam Erez, Assaf Buch, Hanny Yeshua, Muriel Webb, Zamir Halpern, Oren Shibolet
BACKGROUND: Soluble receptor for advanced glycation end-products (sRAGE) exerts protective metabolic effects. AIMS: To identify if sRAGE plays a protective role in NAFLD. METHODS: sRAGE (n=55) and Nε-(Carboxymethyl) lysine (CML) (n=36) serum levels were measured in NAFLD patients. Liver steatosis and fibrosis were non-invasively quantified by the hepatorenal index and the NAFLD fibrosis score (NFS). RESULTS: sRAGE levels were lower in NAFLD patients compared to controls (1207±439 vs...
January 19, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28178913/training-us-health-care-professionals-on-human-trafficking-where-do-we-go-from-here
#16
Clydette Powell, Kirsten Dickins, Hanni Stoklosa
Some 21 million adults and children are labor-trafficked or sex-trafficked through force, fraud, or coercion. In recognition of the interface between trafficking victims and the healthcare setting, over the last 10 years there has been a notable increase in training of health care professionals (HCPs) on human trafficking (HT) and its health implications. Many organizations have developed curricula and offered training in various clinical settings. However, methods and content of this education on trafficking vary widely, and there is little evaluation of the impact of the training...
2017: Medical Education Online
https://www.readbyqxmd.com/read/28135852/a-cultural-competence-organizational-review-for-community-health-services
#17
Mandy Truong, Lisa Gibbs, Veronika Pradel, Michal Morris, Pauline Gwatirisa, Maryanne Tadic, Andrea de Silva, Martin Hall, Dana Young, Elisha Riggs, Hanny Calache, Mark Gussy, Richard Watt, Iqbal Gondal, Elizabeth Waters
Cultural competence is an important aspect of health service access and delivery in health promotion and community health. Although a number of frameworks and tools are available to assist health service organizations improve their services to diverse communities, there are few published studies describing organizational cultural competence assessments and the extent to which these tools facilitate cultural competence. This article addresses this gap by describing the development of a cultural competence assessment, intervention, and evaluation tool called the Cultural Competence Organizational Review (CORe) and its implementation in three community sector organizations...
January 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28132748/plasma-testosterone-and-the-course-of-major-depressive-disorder-in-older-men-and-women
#18
Erik J Giltay, Roos C van der Mast, Esther Lauwen, Annemieke C Heijboer, Margot W M de Waal, Hannie C Comijs
OBJECTIVE: To investigate associations between testosterone levels and major depressive disorder (MDD) in older men and women. METHODS: In a cross-sectional, 2-year prospective analyses within the Netherlands Study on Depression in Older persons cohort study, 469 participants comprised 350 patients with MDD and 119 nondepressed participants in the comparison group (mean age 70.5 ± 7.3 years; 166 [35.4%] men). MDD was assessed by the Composite International Diagnostic Interview...
January 3, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28120636/the-influence-of-childhood-abuse-on-cortisol-levels-and-the-cortisol-awakening-response-in-depressed-and-nondepressed-older-adults
#19
Ilse Wielaard, Roxanne Schaakxs, Hannie C Comijs, Max L Stek, Didi Rhebergen
OBJECTIVES: Childhood abuse has been associated with depression in later life. This may be related to hypothalamic-pituitary-adrenal (HPA) axis functioning. Therefore we aimed to examine the impact of childhood abuse and its interaction with depression on cortisol levels in older adults. METHODS: Data from 418 participants (mean age 70.8 years) in the Netherlands Study of Depression in Older Persons (NESDO) were used; 187 participants experienced childhood abuse; 309 participants had a diagnosis of depression...
January 25, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28108837/can-mechanical-imaging-increase-the-specificity-of-mammography-screening
#20
Magnus Dustler, Daniel Förnvik, Pontus Timberg, Ingvar Andersson, Hannie Petersson, Håkan Brorson, Anders Tingberg, Sophia Zackrisson
OBJECTIVES: This study aimed to investigate the effects of adding adjunct mechanical imaging to mammography breast screening. We hypothesized that mechanical imaging could detect increased local pressure caused by both malignant and benign breast lesions and that a pressure threshold for malignancy could be established. The impact of this on breast screening was investigated with regard to reductions in recall and biopsy rates. METHODS: 155 women recalled from breast screening were included in the study, which was approved by the regional ethical review board (dnr 2013/620)...
January 20, 2017: European Radiology
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