Britte Beaudette-Zlatanova, Robert A Lew, John D Otis, Westyn Branch-Elliman, Eugene Bacorro, Maureen Dubreuil, Caroline Eyvazzadeh, Maneet Kaur, Antonio A Lazzari, Caryn Libbey, Paul A Monach
PURPOSE: Low-dose naltrexone (LDN) is commonly used to control pain and other symptoms, especially in patients with autoimmune diseases, but with limited evidence. This study tests the efficacy of LDN in reducing chronic pain in patients with osteoarthritis (OA) and inflammatory arthritis (IA), where existing approaches often fail to adequately control pain. METHODS: In this randomized, double-blind, placebo-controlled, crossover clinical trial, each patient received 4...
May 2023: Clinical Therapeutics