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https://www.readbyqxmd.com/read/28544443/development-of-a-clinical-trials-version-of-the-impact-of-weight-on-quality-of-life-lite-questionnaire-iwqol-lite-clinical-trials-version-results-from-two-qualitative-studies
#1
R L Kolotkin, C M Ervin, H H Meincke, L Højbjerre, S E Fehnel
Existing measures of health-related quality of life and patient functioning in obesity, such as the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire, lack the developmental rigour required by the Food and Drug Administration (FDA) to support product labelling. Two iterative qualitative studies informed development of a version of the IWQOL-Lite questionnaire optimized for use in obesity clinical trials: the IWQOL-Lite Clinical Trials Version. Study 1 included 42 patients with body mass index (BMI) ≥ 30 kg m(-2) (obesity); and Study 2 included 29 patients with type 2 diabetes and BMI ≥ 27 kg m(-2) (overweight)...
May 22, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28544123/assessing-the-need-for-a-pre-exposure-prophylaxis-programme-using-the-social-media-app-grindr%C3%A2
#2
B Hampel, K Kusejko, D L Braun, J Harrison-Quintana, R Kouyos, J Fehr
OBJECTIVES: HIV pre-exposure prophylaxis (PrEP) is not approved in Switzerland and therefore must be paid for by the users themselves. We conducted a survey to find out whether men who have sex with men (MSM) in Switzerland are already taking PrEP, or are considering using it, and whether it is being taken under medical supervision or not. METHODS: Grindr® is a geosocial networking app for MSM. Between 5 and 24 January 2017, users of the app who were located in Switzerland by a global positioning system (GPS) were asked to participate in a ten-question survey on PrEP use...
May 19, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28542619/perceptions-of-primary-and-secondary-relationships-in-polyamory
#3
Rhonda N Balzarini, Lorne Campbell, Taylor Kohut, Bjarne M Holmes, Justin J Lehmiller, Jennifer J Harman, Nicole Atkins
In consensually non-monogamous relationships there is an open agreement that one, both, or all individuals involved in a romantic relationship may also have other sexual and/or romantic partners. Research concerning consensual non-monogamy has grown recently but has just begun to determine how relationships amongst partners in consensually non-monogamous arrangements may vary. The current research examines this issue within one type of consensual non-monogamy, specifically polyamory, using a convenience sample of 1,308 self-identified polyamorous individuals who provided responses to various indices of relationship evaluation (e...
2017: PloS One
https://www.readbyqxmd.com/read/28542366/illicit-drug-use-and-its-association-with-key-sexual-risk-behaviours-and-outcomes-findings-from-britain-s-third-national-survey-of-sexual-attitudes-and-lifestyles-natsal-3
#4
Rachelle Paquette, Clare Tanton, Fiona Burns, Philip Prah, Maryam Shahmanesh, Nigel Field, Wendy Macdowall, Kirsten Gravningen, Pam Sonnenberg, Catherine H Mercer
OBJECTIVES: We explore the hypothesis that using illicit drugs other than, or in addition to, cannabis is associated with sexual risk behaviour and sexual health outcomes in the British population. METHODS: We analysed data, separately by gender, reported by sexually-active participants (those reporting > = 1 partners/past year) aged 16-44 years (3,395 men, 4,980 women) in Britain's third National Survey of Sexual Attitudes and Lifestyles (Natsal-3), a probability survey undertaken 2010-12 involving computer-assisted personal-interview and computer-assisted self-interview...
2017: PloS One
https://www.readbyqxmd.com/read/28542221/urinary-leakage-during-sexual-intercourse-among-women-with-incontinence-incidence-and-risk-factors
#5
Hui-Hsuan Lau, Wen-Chu Huang, Tsung-Hsien Su
BACKGROUND: Coital incontinence is an under-reported disorder among women with urinary incontinence. Women seldom voluntarily report this condition, and as such, related data remains limited and is at times conflicting. AIMS AND OBJECTIVES: To investigate the incidence and quality of life in women with coital incontinence and to determine associated predictors. METHODS: This observational study involved 505 sexually active women attending the urogynecologic clinic for symptomatic urinary incontinence at a tertiary medical center...
2017: PloS One
https://www.readbyqxmd.com/read/28541239/psychological-parameters-of-psoriasis
#6
A Kouris, E Platsidaki, C Kouskoukis, C Christodoulou
Psoriasis is a chronic, inflammatory scaling dermatosis. The marked visible appearance of the lesions have a negative impact on body image that leads to decreased self-esteem, hence seriously compromising the patient's quality of life. The clinical picture critically affects the social well-being of the patient since the disease is commonly misunderstood and feared by the social environment as being contagious. The patient feels stigmatized and this further intensifies their lack of self-confidence and self-esteem...
January 2017: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28540227/advances-in-the-understanding-of-priapism
#7
REVIEW
Matthew Hudnall, Amanda B Reed-Maldonado, Tom F Lue
Priapism, a persistent penile erection lasting longer than 4 hours and unrelated to sexual activity, is one of the most common emergencies treated by urologists. Priapism can be categorized as ischemic, recurrent ischemic (stuttering), and non-ischemic. Advances in understanding the pathophysiology of various types of priapism have led to targeted management strategies. This review aims to provide an up-to-date picture of the pathophysiology and management of priapism. A search of Medline and PubMed for relevant publications using the term "priapism" was performed...
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28540176/the-effect-of-8-oh-dpat-and-dapoxetine-on-gene-expression-in-the-brain-of-male-rats-during-ejaculation
#8
Xijun Qin, Xiaojun Ma, Dongping Tu, Zuliang Luo, Jie Huang, Changming Mo
The 5-HT1A receptor agonist 8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT) promotes ejaculation of male rats, whereas dapoxetine delays this process. However, the gene expression profile of the brain at ejaculation following administrationof these two compounds has not been fully elucidated. In the present study, a transcriptomic BodyMap was generated by conducting mRNA-Seq on brain samples of male Sprague-Dawley rats. The study included four groups: pre-copulatory control (CK) group, ejaculation (EJ) group, 0...
May 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28538791/inconsistent-reports-of-risk-behavior-among-brazilian-middle-school-students-national-school-based-survey-of-adolescent-health-pense-2009-2012
#9
Dandara de Oliveira Ramos, Martin Daly, Maria Lucia Seidl-de-Moura, Rafael Tavares Jomar, Paulo Nadanovsky
This study assessed the consistency of self-reports of risk behavior (overall and within four specific domains: alcohol use, tobacco use, drug use, and sexual activity) in two editions of the Brazilian National School Based Survey of Adolescent Health (PeNSE): 2009 and 2012. The overall proportion of cases with at least one inconsistent response in the two editions was 11.7% (2.7% on the alcohol items, 2.1% for drug use, 4.3% for cigarette use, 3% for sexual activity) and 22.7% (12.8% on alcohol items, 2.5% for drug use, 4...
May 18, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28538657/social-support-religious-involvement-and-alcohol-use-among-students-at-a-conservative-religious-university
#10
Wendy E Thompson
The misuse of alcohol among college students remains a significant public health concern in the United States. Excessive drinking among college students has been linked to numerous negative consequences, including rape, impaired academic performance, absenteeism from work and school and damaged social relations. This study examined whether religious involvement and social support played a role in reducing the frequency of alcohol use. A non-random convenience sample of 364 students from a larger study of 760 college students-18 years old and older-were recruited over a 2 month period...
May 24, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28538137/evidence-affirming-school-supports-for-australian-transgender-and-gender-diverse-students
#11
Tiffany Jones
Background: The United Nations (UN) and related UN bodies have recognised transgender and gender diverse (TGD) students' rights at the global level to full equitable access to education, and specifically sexuality education, repeatedly. Methods: This article explores the available support for this equal access in Australia. It discusses TGD student rights in a range of Australian laws and education policies. Results: It shows how the inclusion of TGD students, particularly in sexuality education, is reinforced in the current Australian National Curricula...
May 25, 2017: Sexual Health
https://www.readbyqxmd.com/read/28537958/everyday-life-after-colon-cancer-the-visible-and-invisible-challenges
#12
Susanne Stuhlfauth, Line Melby, Ragnhild Hellesø
BACKGROUND: There is little research regarding how everyday life is affected by colon cancer treatment. Few studies exist that exclusively examine patients with Dukes C colon cancer. Most studies include other types of bowel cancer and different stages. OBJECTIVES: The aims of this study were to explore and describe how colon cancer survivors experience everyday life in general and sexuality in particular after treatment of Dukes C colon cancer. METHODS: The study is exploratory and descriptive and uses semistructured interviews to collect data...
May 23, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28537796/coping-with-stress-as-an-lgbtq-healthcare-professional
#13
Michele J Eliason, Carl Streed, Michael Henne
Lesbian, gay, bisexual, transgender, queer, and other sexual/gender minority (LGBTQ+) healthcare providers face both general work-related stresses and working in heteronormative settings with ill-informed or hostile coworkers and patients, yet there has been little study of whether the coping strategies are specific to LGBTQ+ stress. We analyzed qualitative data from 277 healthcare professionals. Sources of stress included religiously and politically conservative coworkers, coworker/patient lack of knowledge, stresses of closeted, and concerns about being out to patients...
May 24, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28537043/ureterorenoscopy-with-stenting-and-its-effect-on-female-sexual-function
#14
Ekrem Akdeniz, Mustafa Suat Bolat
PURPOSE: Various etiological factors have been studied which negatively affect female sexual function, but theeffects of ureteroscopic stone surgery on women's sexual dysfunction remain unknown. The aim of this study wasto investigate the effect of ureteroscopic stone surgery with postoperative stenting on female sexual function. MATERIALS AND METHODS: This study included 30 sexually active female patients who underwent ureteroscopicstone surgery with JJ stenting (study group) and 26 age-matched female patients with ureteral stone surgerywithout JJ stenting (control group)...
May 23, 2017: Urology Journal
https://www.readbyqxmd.com/read/28536557/biocontrol-of-sugarcane-smut-disease-by-interference-of-fungal-sexual-mating-and-hyphal-growth-using-a-bacterial-isolate
#15
Shiyin Liu, Nuoqiao Lin, Yumei Chen, Zhibin Liang, Lisheng Liao, Mingfa Lv, Yufan Chen, Yingxin Tang, Fei He, Shaohua Chen, Jianuan Zhou, Lianhui Zhang
Sugarcane smut is a fungal disease caused by Sporisorium scitamineum, which can cause severe economic losses in sugarcane industry. The infection depends on the mating of bipolar sporida to form a dikaryon and develops into hyphae to penetrate the meristematic tissue of sugarcane. In this study, we set to isolate bacterial strains capable of blocking the fungal mating and evaluate their potential in control of sugarcane smut disease. A bacterial isolate ST4 from rhizosphere displayed potent inhibitory activity against the mating of S...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28536535/role-of-intestinal-lxr%C3%AE-in-regulating-post-prandial-lipid-excursion-and-diet-induced-hypercholesterolemia-and-hepatic-lipid-accumulation
#16
Tibiábin Benítez-Santana, Sarah E Hugo, Amnon Schlegel
Post-prandial hyperlipidemia has emerged as a cardiovascular risk factor with limited therapeutic options. The Liver X receptors (Lxrs) are nuclear hormone receptors that regulate cholesterol elimination. Knowledge of their role in regulating the absorption and handling of dietary fats is incomplete. The purpose of this study was to determine the role of intestinal Lxrα in post-prandial intestinal lipid transport. Using Lxrα knockout (nr1h3(-/-)) and intestine-limited Lxrα over-expressing [Tg(fabp2a:EGFP-nr1h3)] zebrafish strains, we measured post-prandial lipid excursion with live imaging in larvae and physiological methods in adults...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28535892/are-the-women-with-sj%C3%A3-gren-s-syndrome-satisfied-with-their-sexual-activity
#17
Hatice Isik, Metin Isik, Oner Aynioglu, Deniz Karcaaltincaba, Ahmet Sahbaz, Tugba Beyazcicek, Mehmet Ibrahim Harma, Nejat Demircan
OBJECTIVE: Females with Sjögren's Syndrome (SS) often experience vaginal dryness and dyspareunia, along with glandular and extraglandular symptoms. We aimed to evaluate sexual function and life quality in women with SS. METHODS: Forty-six premenopausal women with SS and 47 age-matched controls were studied. Age, duration of the disease, medications, and comorbid diseases were noted. Participants completed 36-Item Short Form Health Survey (SF-36) and Female Sexual Function Index (FSFI)...
May 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28535436/microcystin-lr-induces-changes-in-the-gaba-neurotransmitter-system-of-zebrafish
#18
Wei Yan, Li Li, Guangyu Li, Sujuan Zhao
It has been reported that exposure to microcystins altered adult zebrafish swimming performance parameters, but the possible mechanisms of action remain unknown. Neuronal activity depends on the balance between the number of excitatory and inhibitory processes which are associated with neurotransmitters. In the present study, zebrafish embryos (5 d post-fertilization) were exposed to 0, 0.3, 3 and 30μg/L (microcystin-LR) MCLR for 90day until reaching sexual maturity. To investigate the effects of MCLR on the neurotransmitter system, mRNA levels involved in amino acid g-aminobutyric acid (GABA) and glutamate metabolic pathways were tested using quantitative real-time PCR...
May 15, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28535293/invited-commentary-a-landmark-study-launched-in-a-public-health-maelstrom
#19
Eric A Engels, Charles S Rabkin, James J Goedert
The acquired immune deficiency syndrome (AIDS) epidemic was first recognized in 1981, and it quickly became a public health emergency. In a 1987 paper in the American Journal of Epidemiology (Am J Epidemiol. 1987;126(2): 310-318), Richard Kaslow et al. described the launch of the Multicenter AIDS Cohort Study (MACS), a cohort study of homosexual men in 4 US cities, the purpose of which was to better understand the natural history of AIDS and its determinants. The MACS enrolled participants through a range of community contacts...
May 23, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28534822/violence-victimization-in-korean-adolescents-risk-factors-and-psychological-problems
#20
Subin Park, Yeeun Lee, Hyesue Jang, Minkyung Jo
We examined the risk factors for and psychological problems associated with violence victimization in a nationwide representative sample of Korean adolescents. Data from the 2016 Korean Youth Risk Behavior Web-based Survey was used. Participants were asked about their experience of being a victim of violence that required medical treatment during the past 12 months, as well as their perceived health, happiness, sleep satisfaction, stress, depressed mood, and suicidality. The 12-month prevalence of violence victimization requiring medical treatment was 2...
May 19, 2017: International Journal of Environmental Research and Public Health
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