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https://www.readbyqxmd.com/read/29049007/low-prevalence-of-vaccine-type-hpv-infections-in-young-women-following-the-implementation-of-a-school-based-and-catch-up-vaccination-in-quebec-canada
#1
P Goggin, C Sauvageau, V Gilca, F Defay, G Lambert, S Mathieu-C, J Guenoun, E Comète, F Coutlée
BACKGROUND: In Quebec, Canada, a school-based HPV vaccination for girls has been offered since 2008. The vaccine used in the program targets HPV16/18, responsible for ∼70% of cervical cancers and HPV6/11, responsible for the majority of anogenital warts. The objective of this study was to assess the prevalence of HPV in vaccinated and unvaccinated women. METHODS: Women aged 17-29 years were eligible to participate. Participants' age, vaccination status and diverse risk factors were assessed by a computer-assisted questionnaire...
October 19, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29048765/ageratum-conyzoides-l-inhibits-5-alpha-reductase-gene-expression-in-human-prostate-cells-and-reduces-symptoms-of-benign-prostatic-hypertrophy-in-otherwise-healthy-men-in-a-double-blind-randomized-placebo-controlled-clinical-study
#2
Matthew Detering, Elizabeth Steels, Sundar Rao Koyyalamudi, Elena Allifranchini, Elena Bocchietto, Luis Vitetta
A double-blind, randomized, placebo-controlled clinical trial assessed the efficacy and safety of Ageratum conyzoides in treating benign prostatic hypertrophy (BPH). In this study, 109 men with medically diagnosed BPH, aged 41-76 years, were administered the investigational product, A. conyzoides extract at a dose of 250 mg/d or placebo, q.d. for 12 weeks. The primary outcome measures were the International Prostate Symptom Score (IPSS), daily urinary frequency and safety evaluations. The secondary outcome measures were testosterone, dihydrotestosterone, oestradiol, sex hormone binding globulin (SHBG), Dehydroepiandrosterone sulfate (DHEA-S) and cortisol levels, and prostate specific antigen (PSA), lipids, blood glucose, the Aging Male's Symptom (AMS) Score and sexual function assessed by Derogatis Interview for Sexual Functioning-Self Report (DISF-SR)...
October 19, 2017: BioFactors
https://www.readbyqxmd.com/read/29048584/effect-of-body-size-age-and-premating-experience-on-male-mating-success-in-bactrocera-tryoni-diptera-tephritidae
#3
E W M T D Ekanayake, Anthony R Clarke, Mark K Schutze
Variation in male body size, age, and prior sexual experience may all influence male mating success in tephritid fruit flies. Bactrocera tryoni (Froggatt) is an Australian pest tephritid for which the sterile insect technique (SIT) is being actively pursued, and for which information on what makes males more competitive is urgently needed. Pair-wise competitive mating trials were run using laboratory-reared flies in walk-in field cages, evaluating young, large, and virgin B. tryoni males against old, small, and nonvirgin males, respectively...
October 1, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29045679/prostate-cancer-patient-characteristics-associated-with-a-strong-preference-to-preserve-sexual-function-and-receipt-of-active-surveillance
#4
James R Broughman, Ramsankar Basak, Matthew E Nielsen, Bryce B Reeve, Deborah S Usinger, Kiayni C Spearman, Paul A Godley, Ronald C Chen
Background: Men with early-stage prostate cancer have multiple options that have similar oncologic efficacy but vary in terms of their impact on quality of life. In low-risk cancer, active surveillance is the option that best preserves patients' sexual function, but it is unknown if patient preference affects treatment selection. Our objectives were to identify patient characteristics associated with a strong preference to preserve sexual function and to determine whether patient preference and baseline sexual function level are associated with receipt of active surveillance in low-risk cancer...
October 16, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29044968/a-prospective-randomised-placebo-controlled-study-of-the-impact-of-dutasteride-tamsulosin-combination-therapy-on-sexual-function-domains-in-sexually-active-men-with-lower-urinary-tract-symptoms-luts-secondary-to-benign-prostatic-hyperplasia-bph
#5
Claus G Roehrborn, Michael J Manyak, Juan Manuel Palacios-Moreno, Timothy H Wilson, Erik Pm Roos, Javier Cambronero Santos, Dimitrios Karanastasis, Janet Plastino, Francois Giuliano, Raymond C Rosen
OBJECTIVE: To prospectively assess the impact of the fixed-dose combination of the 5-alpha reductase inhibitor (5ARI), dutasteride 0.5 mg and the alpha-1 blocker, tamsulosin 0.4 mg (DUT-TAM FDC) therapy on sexual function domain scores in sexually active males with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH), using the Men's Sexual Health Questionnaire (MSHQ). PATIENTS AND METHODS: This European and Australian double-blind, placebo-controlled, parallel-group study was conducted at 51 centres...
October 16, 2017: BJU International
https://www.readbyqxmd.com/read/29043852/beliefs-about-others-perceptions-gender-typicality-scale-development-and-relationships-to-gender-nonconformity-sexual-orientation-and-well-being
#6
Laura Green, Katharine A Rimes, Qazi Rahman
The purpose of this study was to develop a measure of "other-perceived" gender typicality and test its relationship with gender nonconformity, sexual orientation, and psychological distress. Data on these variables were collected from 632 participants (142 heterosexual men, 77 gay men, 50 bisexual men, 174 heterosexual women, 85 lesbian women, and 104 bisexual women). We designed a Beliefs About Others' Perceptions-Gender Typicality (BOP-GT) scale on which participants reported how masculine or feminine they thought other people perceived their gendered behavior, interests, appearance, and activities...
October 18, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29043841/tactics-young-women-use-to-resist-condom-use-when-a-partner-wants-to-use-a-condom
#7
Rhiana Wegner, Melissa A Lewis, Kelly Cue Davis, Elizabeth C Neilson, Jeanette Norris
Although there is a growing literature on men's condom use resistance (CUR) tactics (e.g., direct requests, deception), little research exists on women's CUR tactics. This study investigated young women's (ages 18 to 21) self-reported use of CUR tactics since age 14 and related individual difference factors. Participants included 235 sexually active heterosexual women from a nationwide convenience survey sample who completed a newly adapted women's version of the Condom Use Resistance Survey. Consistent with the limited previous research, women were most likely to use risk-level reassurance (37...
October 18, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29042818/cycle-control-with-an-extended-regimen-oral-contraceptive-combining-levonorgestrel-and-ethinyl-estradiol-that-includes-continuous-low-dose-ethinyl-estradiol-instead-of-the-traditional-hormone-free-interval
#8
Rossella E Nappi, Paloma Lobo Abascal, Jennifer Hsieh, Marie-Christine Micheletti
PURPOSE: To evaluate scheduled and unscheduled bleeding and spotting over 1 year of treatment with 91-day extended-regimen combined oral contraception (COC) providing continuous low-dose ethinyl estradiol (EE) in place of the traditional 7-day hormone-free interval (HFI). PATIENTS AND METHODS: This post hoc analysis of a multicenter, open-label, 1-year, Phase 3 study of extended-regimen COC with 30 µg EE/150 µg levonorgestrel (LNG) for 84 days and EE 10 µg for 7 days included 799 sexually active, adult women who completed at least one 91-day cycle of therapy...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29042497/a-single-dual-function-enzyme-controls-the-production-of-inflammatory-nod-agonist-peptidoglycan-fragments-by-neisseria-gonorrhoeae
#9
Jonathan D Lenz, Kathleen T Hackett, Joseph P Dillard
Neisseria gonorrhoeae gonococcus (GC) is a Gram-negative betaproteobacterium and causative agent of the sexually transmitted infection gonorrhea. During growth, GC releases lipooligosaccharide (LOS) and peptidoglycan (PG) fragments, which contribute significantly to the inflammatory damage observed during human infection. In ascending infection of human Fallopian tubes, inflammation leads to increased risk of ectopic pregnancy, pelvic inflammatory disease, and sterility. Of the PG fragments released by GC, most are disaccharide peptide monomers, and of those, 80% have tripeptide stems despite the observation that tetrapeptide stems make up 80% of the assembled cell wall...
October 17, 2017: MBio
https://www.readbyqxmd.com/read/29042182/are-endocrine-disrupting-compounds-environmental-risk-factors-for-autism-spectrum-disorder
#10
REVIEW
Amer Moosa, Henry Shu, Tewarit Sarachana, Valerie W Hu
Recent research on the etiology of autism spectrum disorder (ASD) has shifted in part from a singular focus on genetic causes to the involvement of environmental factors and their gene interactions. This shift in focus is a result of the rapidly increasing prevalence of ASD coupled with the incomplete penetrance of this disorder in monozygotic twins. One such area of environmentally focused research is the association of exposures to endocrine disrupting compounds (EDCs) with elevated risk for ASD. EDCs are exogenous chemicals that can alter endogenous hormone activity and homeostasis, thus potentially disrupting the action of sex and other natural hormones at all stages of human development...
October 14, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/29041962/comparative-assessment-of-an-gambiae-and-an-stephensi-mosquitoes-to-determine-transmission-reducing-activity-of-antibodies-against-p-falciparum-sexual-stage-antigens
#11
Maarten Eldering, Anaïs Bompard, Kazutoyo Miura, Will Stone, Isabelle Morlais, Anna Cohuet, Geert-Jan van Gemert, Patrick M Brock, Sanna R Rijpma, Marga van de Vegte-Bolmer, Wouter Graumans, Rianne Siebelink-Stoter, Dari F Da, Carole A Long, Merribeth J Morin, Robert W Sauerwein, Thomas S Churcher, Teun Bousema
BACKGROUND: With the increasing interest in vaccines to interrupt malaria transmission, there is a demand for harmonization of current methods to assess Plasmodium transmission in laboratory settings. Potential vaccine candidates are currently tested in the standard membrane feeding assay (SMFA) that commonly relies on Anopheles stephensi mosquitoes. Other mosquito species including Anopheles gambiae are the dominant malaria vectors for Plasmodium falciparum in sub-Saharan Africa. METHODS: Using human serum and monoclonal pre-fertilization (anti-Pfs48/45) and post-fertilization (anti-Pfs25) antibodies known to effectively inhibit sporogony, we directly compared SMFA based estimates of transmission-reducing activity (TRA) for An...
October 17, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29040879/influence-of-sexual-behavior-of-dorper-rams-treated-with-glutamate-and-or-testosterone-on-reproductive-performance-of-anovulatory-ewes
#12
Guadalupe Calderón-Leyva, Cesar A Meza-Herrera, Rafael Martinez-Rodriguez, Oscar Angel-García, Raymundo Rivas-Muñoz, Juan V Delgado-Bermejo, Francisco G Véliz-Deras
The aim of this study was to determine if exogenous administration of glutamate and (or) testosterone to male rams during the season of reproductive arrest is able to re-activate male sexual behavior and, later on, to promote through the male effect, both sexual and reproductive competence of anovulatory nulliparous ewes. Therefore, an experiment was performed under long-day photoperiods (spring; photo-reproductive arrest, 26°N). Dorper rams were randomly divided into four homogeneous experimental groups (n = 5 males each) regarding live weight (LW), body condition score (BCS), scrotal circumference (SC) and odor intensity (OI)...
October 9, 2017: Theriogenology
https://www.readbyqxmd.com/read/29040840/experiences-of-structural-vulnerability-among-exotic-dancers-in-baltimore-maryland-co-occurring-social-and-economic-antecedents-of-hiv-sti-risk
#13
Meredith L Brantley, Katherine H A Footer, Sahnah Lim, Deanna Kerrigan, Susan G Sherman
BACKGROUND: Women who grow up in economic scarcity often face limited opportunities for upward mobility, as a result of challenges securing stable housing, quality education, and steady employment. Chronic instability may limit the capacity of women to protect themselves against HIV/STI-related harm when engaging in sexual activity or drug use. Characterizing the structural contexts that facilitate HIV/STI risk among women are critical to effective design and implementation of drug and sexual harm reduction interventions...
October 14, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29040653/regulatory-mechanisms-of-sperm-flagellar-motility-by-metachronal-and-synchronous-sliding-of-doublet-microtubules
#14
Gen L Takei, Masakatsu Fujinoki, Kaoru Yoshida, Sumio Ishijima
STUDY QUESTION: What is the role of metachronal and synchronous sliding in sperm flagellar motility? SUMMARY ANSWER: Both metachronal and oscillatory synchronous sliding are essential for sperm flagellar motility, while the change in mode of synchronous sliding between the non-oscillatory synchronous sliding of a specific pair of the doublet microtubules and the oscillatory synchronous sliding between most pairs of doublet microtubules modulates the sperm flagellar motility...
October 11, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29040165/dating-violence-against-hiv-infected-youth-in-south-africa-associations-with-sexual-risk-behavior-medication-adherence-and-mental-health
#15
Rachel Kidman, Avy Violari
BACKGROUND: As perinatal HIV-infected youth become sexually active, the potential for onward transmission becomes an increasing concern. In other populations, intimate partner violence (IPV) is a risk factor for HIV acquisition. We build on this critical work by studying the role of IPV in facilitating onward transmission among HIV-infected youth - an important step towards effective intervention. SETTING: Soweto, South Africa. METHODS: Self-report surveys were completed by 129 perinatal HIV-infected female youth (aged 13-24)...
October 14, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29039629/adolescents-contraception-continuation-in-switzerland-a-prospective-observational-study
#16
Cécile Diserens, Adeline Quach, Patrice Mathevet, Pierluigi Ballabeni, Martine Jacot-Guillarmod
BACKGROUND: Securing the adherence over time to contraception by adolescent girls is a challenge. Until now little was known about this topic in Switzerland. The aim of our study was to determine contraceptive continuation rates among adolescents in this country and assess possible predictive factors for discontinuation. METHODS: A prospective observational cohort study of 12- to 19-year-old girls starting contraception was performed. Patients were interviewed again after 1 year by phone, email or postal mail...
October 17, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29038690/a-bayesian-network-analysis-of-posttraumatic-stress-disorder-symptoms-in-adults-reporting-childhood-sexual-abuse
#17
Richard J McNally, Alexandre Heeren, Donald J Robinaugh
Background: The network approach to mental disorders offers a novel framework for conceptualizing posttraumatic stress disorder (PTSD) as a causal system of interacting symptoms. Objective: In this study, we extended this work by estimating the structure of relations among PTSD symptoms in adults reporting personal histories of childhood sexual abuse (CSA; N = 179).   Method: We employed two complementary methods. First, using the graphical LASSO, we computed a sparse, regularized partial correlation network revealing associations (edges) between pairs of PTSD symptoms (nodes)...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29037754/antiviral-effects-of-lactobacillus-crispatus-against-hsv-2-in-mammalian-cell-lines
#18
Elham Mousavi, Manoochehr Makvandi, Ali Teimoori, Angila Ataei, Shokouh Ghafari, Alireza Samarbaf-Zadeh
BACKGROUND: Herpes simplex virus type 2 (HSV-2) infectious disease is one of the most common viral sexually transmitted diseases. As regards, vaginal lactobacilli play an important role in protecting host against the urogenital pathogens; here we assessed the potential antiviral activity of Lactobacillus crispatus against HSV-2 infection in vitro. METHODS: Both Vero and HeLa cell lines were treated by L. crispatus before, during and after HSV-2 infection. The pre-incubation assay was also performed for the evaluating of virus adsorption by L...
October 13, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29037602/hiv-sti-prevention-among-heterosexually-active-black-adolescents-with-mental-illnesses-focus-group-findings-for-intervention-development
#19
Bridgette M Brawner, Loretta Sweet Jemmott, Gina Wingood, Janaiya Reason, Niya Mack
Heterosexually active Black adolescents with mental illnesses are at increased risk for sexually transmitted infections (STIs), including HIV. However, few HIV/STI prevention interventions exist for this demographic. We held seven focus groups (N = 33) to elucidate social, cultural, and psychological factors that influence HIV/STI risk-related sexual behaviors in this understudied population. Seven themes emerged: (a) Blackness and media portrayals, (b) Blackness as a source of cultural resilience and pride, (c) psychosocial determinants of condom use, (d) consequences of engaging in sexual activity, (e) attitudes and beliefs toward sexual behaviors, (f) benefits of sexual activity, and (g) coping mechanisms...
September 28, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29037533/continuous-tamoxifen-delivery-improves-locomotor-recovery-6h-after-spinal-cord-injury-by-neuronal-and-glial-mechanisms-in-male-rats
#20
Jennifer M Colón, Pablo A González, Ámbar Cajigas, Wanda I Maldonado, Aranza I Torrado, José M Santiago, Iris K Salgado, Jorge D Miranda
No treatment is available for patients with spinal cord injury (SCI). Patients often arrive to the hospital hours after SCI suggesting the need of a therapy that can be used on a clinically relevant window. Previous studies showed that Tamoxifen (TAM) treatment 24h after SCI benefits locomotor recovery in female rats. Tamoxifen exerts beneficial effects in male and female rodents but a gap of knowledge exists on: the therapeutic window of TAM, the spatio-temporal mechanisms activated and if this response is sexually dimorphic...
October 13, 2017: Experimental Neurology
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