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https://www.readbyqxmd.com/read/28102924/current-practices-related-to-family-presence-during-acute-deterioration-in-adult-emergency-department-patients
#1
Megan J Youngson, Judy Currey, Julie Considine
AIMS: To explore the characteristics and interactions of clinicians, patients and family members during management of the deteriorating adult patient in the Emergency Department. BACKGROUND: Previous research into family presence during resuscitation has identified many positive outcomes when families are included. However, over that last three decades the epidemiology of acute clinical deterioration has changed, with a decrease in in-hospital cardiac arrests and an increase in acute clinical deterioration...
January 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28101899/recommendations-for-the-use-of-sensor-augmented-pumps-with-predictive-low-glucose-suspend-features-in-children-the-importance-of-education
#2
REVIEW
Andrea E Scaramuzza, Claudia Arnaldi, Valentino Cherubini, Elvira Piccinno, Ivana Rabbone, Sonia Toni, Stefano Tumini, Gilberto Candela, Paola Cipriano, Lucia Ferrito, Lorenzo Lenzi, Davide Tinti, Ohad Cohen, Fortunato Lombardo
Sensor-augmented pumps, which consist of a pump and a continuous glucose monitoring system, offer considerable therapeutic opportunities, despite requiring close attention in the early phase of their use. The aim of this paper is to provide recommendations on the use of a predictive low glucose management (PLGM) system (Minimed 640G™, Medtronic, Northridge, CA, USA) in adolescents with type 1 diabetes either at the start of therapy or during follow-up. Sound clinical recommendations on PLGM are of increasing importance since several recent papers have reported significant clinical improvements in patients with PLGM, especially in adults...
January 19, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28096031/the-effect-of-nurse-led-care-on-stability-time-in-therapeutic-range-of-inr-in-ischemic-stroke-patients-receiving-warfarin
#3
Mina Amiri, Marzieh Kargar, Afshin Borhanihaghighi, Fahimeh Soltani, Najafe Zare
PURPOSE: The current study is designed in order to investigate the effect of nurse-led care (the supportive and educational measurements by nurses) on stability time in therapeutic range of INR in ischemic stroke patients receiving Warfarin. METHOD: In this quasi-experimental study, 80 ischemic stroke patients were investigated, 40 patients in experimental group and 40 in the control group referred to the nurse-based warfarin clinics affiliated to Shiraz University of Medical Sciences...
February 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28093058/off-label-prescribing-of-psychotropic-medication-2005-2013-an-examination-of-potential-influences
#4
Peggy L O'Brien, Nicholas Cummings, Tami L Mark
OBJECTIVE: This study examined rates of psychotropic prescriptions for various on- and off-label uses in 2005 and 2013 in the context of changes in labeled indications. METHODS: The National Disease and Therapeutic Index, a survey of nationally representative office-based physicians that identifies the diagnosis attached to each prescription, was used to capture the number of psychiatric medications prescribed for a particular diagnosis in 2005 (N=4,120) and 2013 (N=4,140)...
January 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28091973/mechanisms-on-spasmolytic-and-anti-inflammatory-effects-of-a%C3%A2-herbal-medicinal-product-consisting-of-myrrh-chamomile-flower-and-coffee-charcoal
#5
Cica Vissiennon, Karl-Heinz Goos, Jürgen Arnhold, Karen Nieber
Inflammatory bowel disease or irritable bowel syndrome are chronic gastrointestinal disorders which are associated with a lifelong therapeutic need. The disease results in physical, psychological, and social problems with an impact on partnership, sexuality, education, and career. Thus, the number of patients and health care professionals relying on traditional and complementary medicines and especially phytotherapy for the treatment of these chronic conditions is increasing over recent years. One traditional herbal medicinal product consisting of chamomile flower, myrrh, and coffee charcoal has been widely used in clinical practice within this indication area...
January 13, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28090718/an-analysis-of-policies-for-cotrimoxazole-amoxicillin-and-azithromycin-use-in-namibia-s-public-sector-findings-and-therapeutic-implications
#6
Dan Kibuule, Mwangana Mubita, Ester Naikaku, Francis Kalemeera, Brian B Godman, Evans Sagwa
BACKGROUND: Despite Namibia's robust medicine use systems and policies, antibiotic use indicators remain suboptimal. Recent medicine use surveys rank cotrimoxazole, amoxicillin and azithromycin (CAA) among the most used medicines. However, there is rising resistance to CAA (55.9%-96.7%). Unfortunately, to date, there have been limited studies evaluating policies to improve antibiotic use in Namibia. AIM: To evaluate public sector pharmaceutical policies and guidelines influencing the therapeutic use of CAA antibiotics in Namibia...
January 16, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28089411/apheresis-medicine-education-in-the-united-states-of-america-state-of-the-discipline
#7
REVIEW
Monica B Pagano, Gay Wehrli, Darlene Cloutier, Eileen Galvin Karr, Ileana Lopez-Plaza, Joseph Schwartz, Chester Andrzejewski, Jeffrey L Winters, Edward C C Wong, Yanyun Wu, Nicole D Zantek
Apheresis Medicine is a medical discipline that involves a variety of procedures (based on the targeted component to be removed or collected), indications (therapeutic vs. donation), and personnel (operators, management, and medical oversight). Apheresis services are accredited and/or regulated by a number of agencies and organizations. Given the complexity and the heterogeneity of apheresis services, it has been particularly challenging to formulate educational goals and define curriculums that easily cover all aspects of Apheresis Medicine...
December 29, 2016: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28081318/clinical-characteristics-and-outcome-of-brucella-endocarditis
#8
Na Du, Feng Wang
BACKGROUND/AIM: Brucella endocarditis, which is a rare condition, is the most common cause of death in human brucellosis, leading to severe cardiac complications. By collecting and analyzing clinical cases, we analyzed the clinical characteristics and outcome of Brucella endocarditis in endemic areas in China. MATERIALS AND METHODS: Presented here are 5 cases of Brucella endocarditis, all managed uniformly. We present the clinical, serological, and echocardiographic features; the therapeutic approach; and the follow-up of five patients with Brucella endocarditis...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28078408/-rehabilitation-in-children-and-adults-an-overview
#9
A Illg
BACKGROUND: The rehabilitation of patients with hearing loss includes technical, medical, and therapeutic education interventions. The success of cochlear implant (CI) treatment depends on joint coordination and execution of all measures. During the history of CI, expansion of the spectrum of indication criteria has led to evolution of auditory-verbal therapy, speech therapy, and auditory training. MATERIALS AND METHODS: This paper describes the current status of therapeutic knowledge and experience of hearing and speech therapeutic rehabilitation in children and adults...
January 11, 2017: HNO
https://www.readbyqxmd.com/read/28077444/protein-interactions-during-the-flavivirus-and-hepacivirus-life-cycle
#10
Gisa Gerold, Janina Bruening, Bettina Weigel, Thomas Pietschmann
Protein-protein interactions govern biological functions in cells, in the extracellular milieu and at the border between cells and extracellular space. Viruses are small intracellular parasites and thus rely on protein interactions to produce progeny inside host cells and to spread from cell to cell. Usage of host proteins by viruses can have severe consequences e.g. apoptosis, metabolic disequilibria or altered cell proliferation and mobility. Understanding protein interactions during virus infection can thus educate us on viral infection and pathogenesis mechanisms...
January 11, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28077222/prediction-of-relapse-after-cognitive-behavioral-treatment-of-gambling-disorder-in-individuals-with-chronic-schizophrenia-a-survival-analysis
#11
Enrique Echeburúa, Montserrat Gómez, Montserrat Freixa
Gambling disorder (GD) in individuals with chronic schizophrenia is relevant because there are higher rates of GD in schizophrenic populations (10%) than in the nonschizophrenic population (1%-5%). In addition, these patients have more severe alcohol use disorder (i.e., meeting at least 6 of the DSM-5 11 criteria for diagnosis of this disorder), higher depression scores, a poor adherence to treatment, and more frequent use of outpatient mental health care. One of the main problems in GD is therapeutic failure (defined as three or more lapse episodes during treatment) or relapse (three or more lapse episodes in the follow-up period)...
January 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28071726/the-ppe2-protein-of-mycobacterium-tuberculosis-translocates-to-host-nucleus-and-inhibits-nitric-oxide-production
#12
Khalid Hussain Bhat, Shruti Srivastava, Sandeep Kumar Kotturu, Sudip Ghosh, Sangita Mukhopadhyay
Mycobacterium tuberculosis, the bacterium that causes tuberculosis, is one of the most successful pathogens of humans. It has evolved several adaptive skills and evasion mechanisms to hijack the immunologically educated host to suit its intracellular lifestyle. Here, we show that one of the unique PPE family member proteins of M. tuberculosis, PPE2, can limit nitric oxide (NO) production by inhibiting inos gene transcription. PPE2 protein has a leucine zipper DNA-binding motif and a functional nuclear localization signal...
January 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28069663/cybercycling-effects-on-classroom-behavior-in-children-with-behavioral-health-disorders-an-rct
#13
April Bowling, James Slavet, Daniel P Miller, Sebastien Haneuse, William Beardslee, Kirsten Davison
BACKGROUND AND OBJECTIVES: Exercise is linked with improved cognition and behavior in children in clinical and experimental settings. This translational study examined if an aerobic cybercycling intervention integrated into physical education (PE) resulted in improvements in behavioral self-regulation and classroom functioning among children with mental health disabilities attending a therapeutic day school. METHODS: Using a 14-week crossover design, students (N = 103) were randomly assigned by classroom (k = 14) to receive the 7-week aerobic cybercycling PE curriculum during fall 2014 or spring 2015...
January 9, 2017: Pediatrics
https://www.readbyqxmd.com/read/28068147/do-wellness-tourists-get-well-an-observational-study-of-multiple-dimensions-of-health-and-well-being-after-a-week-long-retreat
#14
Marc M Cohen, Fiona Elliott, Liza Oates, Adrian Schembri, Nitin Mantri
BACKGROUND: Wellness retreats use many complementary and alternative therapies within a holistic residential setting, yet few studies have evaluated the effect of retreat experiences on multiple dimensions of health and well-being, and no published studies have reported health outcomes in wellness tourists. OBJECTIVES: To assess the effect of a week-long wellness-retreat experience in wellness tourists. DESIGN: A longitudinal observational study with outcomes assessed upon arrival and departure and 6 weeks after the retreat...
January 9, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28065677/multistrategic-approach-to-improve-quality-of-care-of-people-with-diabetes-at-the-primary-care-level-study-design-and-baseline-data
#15
Mariana Prestes, María Angelica Gayarre, Jorge Federico Elgart, Lorena Gonzalez, Enzo Rucci, Juan José Gagliardino
AIM: To test the one year-post effect of an integrated diabetes care program that includes system changes, education, registry (clinical, metabolic and therapeutic indicators) and disease management (DIAPREM), implemented at primary care level, on care outcomes and costs. METHODS: We randomly selected 15 physicians and 15 nurses from primary care units of La Matanza County to be trained (Intervention-IG) and another 15 physicians/nurses to use as controls (Control-CG)...
January 5, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28062327/psychosocial-care-of-the-pediatric-oncology-patient-undergoing-surgical-treatment
#16
REVIEW
Marci Mechtel, Ashley Stoeckle
OBJECTIVE: To review the psychosocial aspects experienced by children with cancer undergoing surgical and procedural treatments. DATA SOURCES: CINAHL, PubMed, and PsycINFO resources. CONCLUSION: The diagnosis of cancer is a threatening experience for the pediatric patient with cancer leading to anxiety and distress, which is elevated with a surgical or procedural approach to treatment. Assessing the child's developmental level and previous experiences are fundamental in identifying the appropriate interventions to reduce anxiety and distress to support effective coping...
January 4, 2017: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/28061987/management-of-multiple-myeloma-in-resource-constrained-settings
#17
REVIEW
Lalit Kumar, Ranjit Kumar Sahoo
The prognosis of patients with multiple myeloma (MM) has improved significantly in the past two decades. This is attributed to use of novel agents for induction, high-dose chemotherapy and autologous stem cell transplantation (ASCT), maintenance therapy, and improved supportive care. Currently, evidence-based management guidelines/recommendations developed by International societies/groups are being followed partially in low-resource settings. Lack of quality diagnostics (eg, cytogenetics/fluorescence in situ hybridization (FISH), serum free light chains), novel therapeutics, and trained manpower, and limited financial resources are key challanges...
December 2016: Seminars in Oncology
https://www.readbyqxmd.com/read/28060744/targeting-macrophage-anti-tumor-activity-to-suppress-melanoma-progression
#18
REVIEW
Huafeng Wang, Lijuan Zhang, Luhong Yang, Chengfang Liu, Qi Zhang, Linjing Zhang
By phagocytosing cancer cells and their cellular debris, macrophages play a critical role in nonspecific defense (innate immunity) and, as antigen presenters, they help initiate specific defense mechanisms (adaptive immunity). Malignant melanoma is a lethal disease due to its aggressive capacity for metastasis and resistance to therapy. For decades, considerable effort has gone into development of an effective immunotherapy for treatment of metastatic melanoma. In this review, we focus on the anti-tumor activities of macrophages in melanoma and their potential as therapeutic targets in melanoma...
January 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28060178/assessment-of-splints-applied-for-pediatric-fractures-in-an-emergency-department-urgent-care-environment
#19
Joshua M Abzug, Brandon S Schwartz, Aaron J Johnson
BACKGROUND: Fractures are common in the pediatric population. The initial evaluation is rarely by an orthopaedic surgeon, but commonly an emergency room or urgent care center physician/extender. This typically involves splint application by a nonorthopaedist to immobilize the extremity and provide stabilization. Iatrogenic injuries from inappropriate splint placement are a potential public health and legal concern that can lead to complications. The primary purpose of this study was to prospectively evaluate the adequacy of all splints placed on patients who presented to a pediatric orthopaedic office; secondary outcomes included assessing prevalence and types of complications that were associated with inadequate splints...
January 5, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28056246/-the-present-status-and-future-prospects-of-application-of-digital-medical-technology-in-general-surgery-in-china
#20
C H Fang, Y Y LauWan, W Cai
It has been almost 10 years since digital medical technology has started to becommonly used in general surgery in China.Led by advances in three dimensional(3D) visualization technology, virtual reality, simulation surgery, and 3D printing, digital medical technology have played important roles in changing the current practice of general surgery in China to become more effective by improving diagnostic accuracy and a better choice of therapeutic procedure with a resultant increased surgical success rate and a decreased surgical risks...
January 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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