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retinal vasculitis

Richard F Spaide
PURPOSE: To investigate the structural optical coherence tomography and related microvascular flow characteristics in eyes with retinal vasculitis. METHODS: Regions involved with perivascular infiltration in eyes with retinal vasculitis, but no evidence of large vessel occlusion were evaluated with optical coherence tomography (OCT), OCT angiography, and fluorescein angiography. RESULTS: Ten eyes of 5 patients with a variety of etiologies of retinal vasculitis were evaluated...
October 18, 2016: Retina
Mohammed El Amine Ghembaza, Ali Lounici
No abstract text is available yet for this article.
October 11, 2016: Ocular Immunology and Inflammation
Fatemeh Bazvand, Mohammad Zarei, Nazanin Ebrahimiadib, Reza Karkhaneh, Samaneh Davoudi, Mahyar Soleimanzadeh, Elaheh Sharifian, Ramak Roohipoor, Bobeck S Modjtahedi
PURPOSE: Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behçet's disease as well as the relationship between visual acuity and angiographic findings. METHODS: Retrospective chart review of patients with Behçet's disease seen at the Farabi Eye Hospital. RESULTS: Forty-six patients (92 eyes) with mean age of 33.41 ± 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively...
August 10, 2016: Seminars in Ophthalmology
Christopher P Donovan, Paula E Pecen, Kimberly Baynes, Justis P Ehlers, Sunil K Srivastava
A 31-year-old woman with a history of anti-synthetase syndrome-related myositis and interstitial lung disease presented with acute-onset blurry vision and rash on her hands and feet. Visual acuity was hand motion in her right eye and 20/40 in her left eye. Dilated fundus exam showed extensive retinal vasculitis, diffuse intraretinal hemorrhages, and subretinal fluid. Optical coherence tomography revealed significant macular thickening, and fluorescein angiography revealed vascular leakage with peripheral nonperfusion...
September 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Sanjeet K Shahi
Acute retinal necrosis (ARN), secondary to herpes simplex encephalitis, is a rare syndrome that can present in healthy individuals, as well as immuno-compromised patients. Most cases are caused by a secondary infection from the herpes virus family, with varicella zoster virus being the leading cause of this syndrome. Potential symptoms include blurry vision, floaters, ocular pain and photophobia. Ocular findings may consist of severe uveitis, retinal vasculitis, retinal necrosis, papillitis and retinal detachment...
August 31, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
David S Ehmann, Murtaza K Adam, Sundeep K Kasi, Arunan Sivalingam, James P Dunn
PURPOSE: To describe two cases of vasculitis: one hemorrhagic and one nonhemorrhagic after uncomplicated cataract surgery with intracameral vancomycin. METHODS: Retrospective case series. RESULTS: A 74-year-old female and a 54-year-old female developed severe visual loss within 2 weeks of uncomplicated cataract surgery with intracameral vancomycin. The first patient developed a fulminant hemorrhagic vasculitis, whereas the second patient developed a less severe nonhemorrhagic vasculitis...
August 22, 2016: Retinal Cases & Brief Reports
Nicole Balducci, Giacomo Savini, Piero Barboni, Pietro Ducoli, Antonio Ciardella
A case of monocular postoperative hemorrhagic occlusive retinal vasculitis (HORV) after uncomplicated bilateral cataract surgery is described. HORV is a severe syndrome that leads to painless visual loss after uncomplicated cataract surgery. The same surgical procedure was adopted in both eyes except for the use of intracameral vancomycin, which was injected only in the eye that developed HORV. Diffuse retinal ischemia with vascular sheathing and intraretinal hemorrhages were detected during the fourth postoperative day...
August 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Philip Storey, Anna Ter-Zakarian, Narsing Rao, Damien Rodger
PURPOSE: To describe a patient with undiagnosed systemic lupus erythematosus and secondary antiphospholipid syndrome presenting with bilateral severe retinal vaso-occlusion on first presentation. METHODS: Retrospective case report. A 42-year-old Hispanic female with no medical history presented with 2 weeks of bilateral decreased vision. RESULTS: At initial presentation, the patient's best-corrected visual acuity was 2 ft/200 and 20/400 in the right and left eyes, respectively...
August 19, 2016: Retinal Cases & Brief Reports
Ilknur Tugal-Tutkun, Pınar Cakar Ozdal, Merih Oray, Sumru Onal
Behçet disease is a chronic relapsing multisystem inflammatory disorder. Ocular involvement is characterized by a bilateral recurrent non-granulomatous panuveitis and retinal vasculitis. Posterior segment findings vary during the course of the disease, in parallel with the relapsing and remitting intraocular inflammation. Structural alterations occur with increased disease duration. Fluorescein angiography is the gold standard in revealing the extent and severity as well as the leaky and/or occlusive nature of retinal vasculitis...
August 19, 2016: Ocular Immunology and Inflammation
Jennifer Murdock, Petros E Carvounis
PURPOSE: To describe an adult with chickenpox resulting in systemic vasculitis and bilateral retinal vascular occlusions. METHODS: Single case report. RESULTS: A 58-year-old man with chickenpox complicated by disseminated varicella-zoster systemic and retinal vasculitis resulting in a combined arterial and venous occlusion in one eye with multiple branch retinal vein occlusions in the other eye. There was no evidence of retinitis. The patient systemically improved after treatment with acyclovir and steroids; however, his vision remained poor...
August 16, 2016: Retinal Cases & Brief Reports
Narumon Keorochana
The purpose of this study was to describe a presumed case of Epstein-Barr virus (EBV)-associated retinal vasculitis in a 42-year-old female with sudden unilateral vision loss and successful treatment with acyclovir therapy. Diagnostic vitreous biopsy of the right eye was performed to test for EBV and other known infectious causes of retinitis and evaluate vitreous cells and serological testing. Vitreous polymerase chain reaction viral DNA testing result was positive for EBV but negative for herpes simplex virus, varicella-zoster virus, and cytomegalovirus...
2016: International Medical Case Reports Journal
Yonghui Xia, Yu Su, Ian Hin Yat Wong, Xiaoli Ma, Rui Hua
Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is a disease characterized by multiple retinal macroaneurysms, neuroretinitis and peripheral capillary non-perfusion, leading to irreversible visual loss. It includes five stages and has previously been rarely reported. IRVAN syndrome is especially rare in Asia. In this report, we describe laser diagnosis and therapy in an Asian patient with IRVAN syndrome over two years of follow-up. We observed non-perfusion retina and dilated retinal capillaries in the contralateral eye...
August 1, 2016: Photodiagnosis and Photodynamic Therapy
Rupesh Agrawal, Dinesh V Gunasekeran, Julio J Gonzalez-Lopez, Joao Cardoso, Bhaskar Gupta, Peter K F Addison, Mark Westcott, Carlos E Pavesio
PURPOSE: Describe the clinical features and outcomes of patients with peripheral retinal vasculitis (RV) and describe clinical characteristics of presumed tubercular RV in a nonendemic setting. METHODS: Retrospective cohort study of 110 consecutive patients with peripheral RV at a tertiary referral eye care center in the United Kingdom. Retinal vasculitis was defined as RV with vitritis associated with peripheral retinal ischemia. Patients who also had positive Quantiferon Gold in Tube test, positive tuberculin skin test, and/or other evidence of systemic tuberculosis such as biopsy were labeled with presumed tubercular RV...
August 2, 2016: Retina
Michael T Aaberg, Thomas M Aaberg
PURPOSE: To describe the development of uveitis and retinal vasculitis in association with pembrolizumab treatment for metastatic uveal melanoma. METHODS: A case report and a brief review of the literature are presented. Information collected and reported include the patient's clinical course, physical examination findings, fluorescein angiogram images, retinal photographs, and her response to treatment. RESULTS: A 54-year-old woman was diagnosed with a large choroidal malignant melanoma and had the affected eye enucleated...
August 2, 2016: Retinal Cases & Brief Reports
Peng-Tai Tien, Hui-Ju Lin, Wen-Lu Chen, Chun-Ju Lin, Jane-Ming Lin, Yi-Yu Tsai
No abstract text is available yet for this article.
August 3, 2016: Postgraduate Medical Journal
Basanta Bhaduri, Ryan M Nolan, Ryan L Shelton, Lara A Pilutti, Robert W Motl, Heather E Moss, John H Pula, Stephen A Boppart
Although retinal vasculitis is common in multiple sclerosis (MS), it is not known if MS is associated with quantitative abnormalities in retinal blood vessels (BVs). Optical coherence tomography (OCT) is suitable for examining the integrity of the anterior visual pathways in MS. In this paper we have compared the size and number of retinal blood vessels in patients with MS, with and without a history of optic neuritis (ON), and control subjects from the cross-sectional retinal images from OCT. Blood vessel diameter (BVD), blood vessel number (BVN), and retinal nerve fiber layer thickness (RNFLT) were extracted from OCT images collected from around the optic nerves of 129 eyes (24 control, 24 MS + ON, 81 MS-ON) of 71 subjects...
June 1, 2016: Biomedical Optics Express
Rwituja Thomas, Preeti Puranik, Bhuvanesh Kalal, Carl Britto, Savitha Kamalesh, Sylvan Rego, Anita Shet
INTRODUCTION: Rickettsial infections are re-emerging in the Indian subcontinent, especially among children. Understanding geographical and clinical epidemiology will facilitate early diagnosis and management. METHODOLOGY: Children aged <18yrs hospitalized with clinically-diagnosed rickettsial fever were reviewed retrospectively. Frequency distributions and odds ratios were calculated from tabulated data. RESULTS: Among 262 children hospitalized between January 2008-December 2012, median age was five years, and 61% were male children...
2016: Journal of Infection in Developing Countries
Fereydoun Davatchi, Cheyda Chams-Davatchi, Hormoz Shams, Farhad Shahram, Abdolhadi Nadji, Massoomeh Akhlaghi, Tahreh Faezi, Zahra Ghodsi, Bahar Sadeghi Abdollahi, Farimah Ashofteh, Negin Mohtasham, Hoda Kavosi, Mariam Masoumi
INTRODUCTION: Behcet's Disease (BD) is classified among vasculitides. The aim of this review was to put together different known reports in order to help the reader to better understand the disease, to avoid the frequent misdiagnosis, and to decide the best treatment. AREAS COVERED: a) Epidemiology: BD is rare, and is seen along the Silk Road, from 20 to 420/100,000 in Turkey and 80/100,000 in Iran, to 0.64/100,000 in the UK. b) Clinical manifestations: oral aphthosis is seen in more than 95% of patients, genital aphthosis (60-90%), skin (pseudofolliculitis/erythema nodosum, 40-90%), eyes (uveitis/retinal vasculitis, 45-90%), gastrointestinal (diarrhea/hemorrhage/perforation/pain, 4-38%), vascular (venous/arterial thrombosis, aneurysm, 2...
July 11, 2016: Expert Review of Clinical Immunology
Karen I Gutiérrez-Aguirre, Michael W Stewart, Jason C Sluzevich
BACKGROUND/PURPOSE: To describe the findings and clinical course of a patient with scleromyxedema complicated by retinal vasculitis and macular edema. METHODS: Interventional case report. RESULTS: A 64-year old Caucasian woman with recently diagnosed, biopsy proven scleromyxedema presented with decreased visual acuity (20/50 OD; 20/100 OS) due to retinal vasculitis and macular edema. She received intravitreal bevacizumab and subtenon's triamcinolone acetonide for the macular edema, and bilateral pars plana vitrectomies were required for vitreous hemorrhages...
June 24, 2016: Retinal Cases & Brief Reports
Reza Karkhaneh, Alireza Lashay, Aliasghar Ahmadraji
PURPOSE: To report a case of cytomegalovirus (CMV) retinitis in an immunocompetent adult patient. METHODS: A 61-year-old woman with proven CMV retinitis and no evidence of HIV or other underlying immunodeficiencies was referred. RESULTS: She was referred with history of recent right eye visual loss. In fundus examination, she had signs of retinal vasculitis. After initial examination, she was found to have CMV retinitis documented by polymerase chain reaction (PCR) analysis of vitreous sample...
June 2016: Journal of Current Ophthalmology
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