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retinal vasculitis

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https://www.readbyqxmd.com/read/27896896/presumed-tuberculous-uveitis-in-non-endemic-country-for-tuberculosis-case-series-from-a-new-zealand-tertiary-uveitis-clinic
#1
Ken K Ng, Mitzi Nisbet, Erika M Damato, Joanne L Sims
BACKGROUND: To describe the clinical spectrum of presumed tuberculous (TB) uveitis in a developed, non-endemic country of high immigrant population. DESIGN: Retrospective review of a consecutive case series. PARTICIPANTS: All 39 patients diagnosed with presumed TB uveitis at the tertiary uveitis service in Auckland from 2007 to 2014. METHODS: Clinical chart review. MAIN OUTCOME MEASURES: Patient demographics, risk factors, ophthalmic manifestations, management and outcome...
November 28, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27871395/bilateral-scleritis-and-retinal-vasculitis-in-microscopic-polyangiitis
#2
David Diaz-Valle, Alejandro Gomez-Gomez, Alejandro Pascual-Martin
No abstract text is available yet for this article.
December 2016: Ophthalmology
https://www.readbyqxmd.com/read/27870802/intravitreal-infliximab-in-refractory-uveitis-in-behcet-s-disease-a-safety-and-efficacy-clinical-study
#3
Mostafa M E Hamza, Tamer A Macky, Mohamed Karim Sidky, Gaafar Ragab, Mahmoud M Soliman
PURPOSE: To assess the safety and efficacy of intravitreal infliximab (1 mg/0.05 mL) in patients with refractory posterior uveitis in Behcet's disease. METHODS: Twenty patients were included in this study. Best corrected visual acuity (BCVA), vitreous haze (graded 0-4), vasculitis, retinitis, and papillopathy (presence or absence) were assessed at baseline, Day 1 and Week 2, 4, 6, 8, 12, and 18. Optical coherence tomography (OCT) central foveal thickness, fluorescein angiography, and flash electroretinogram were done at baseline and 4, 12, and 18 weeks...
December 2016: Retina
https://www.readbyqxmd.com/read/27867673/central-retinal-artery-occlusion-in-takayasu-s-arteritis-as-the-first-presentation-of-the-disease
#4
Hande Guclu, Vuslat Pelitli Gurlu, Sadık Altan Ozal, Orkut Guclu
Takayasu's arteritis (TA) is a chronic inflammatory granulomatous vasculitis which affects large and medium arterial vessels. The disease involves especially subclavian arteries and aortic branches but it can consist of any arteries. The major pathology is granulomatous panarteritis with intima proliferation and defects of the elastic lamina of the vessels. We present a case of central retinal artery occlusion in TA as the first presentation of the disease. To the best of our knowledge, the present case is the first case that demonstrates central retinal artery occlusion as an initial manifestation in TA...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27857032/eosinophilic-granulomatosis-with-polyangiitis-presenting-with-skin-rashes-eosinophilic-cholecystitis-and-retinal-vasculitis
#5
Mingbing Zeng, Xialin Liu, Yizhi Liu
BACKGROUND Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome (CSS), is a rare vasculitis of unknown etiology. Most of the patients have a long history of asthma and then develop autoimmune inflammation of small and medium-sized blood vessels, with consequent reduction of blood flow to various organs and tissues. EGPA can cause disorders in multiple systems; the most seriously affected organs are the retina, kidney, brain, cardiovascular system, and skin. CASE REPORT The patient was hospitalized for high fever and skin rashes and then developed right upper abdominal pain, decreased visual acuity, coma, and convulsions...
November 18, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27853889/efficacy-and-safety-of-adalimumab-in-beh%C3%A3-et-s-disease-related-uveitis-a-multicenter-retrospective-observational-study
#6
Claudia Fabiani, Antonio Vitale, Giacomo Emmi, Lorenzo Vannozzi, Giuseppe Lopalco, Silvana Guerriero, Ida Orlando, Rossella Franceschini, Daniela Bacherini, Luca Cimino, Alessandra Soriano, Bruno Frediani, Mauro Galeazzi, Florenzo Iannone, Gian Marco Tosi, Carlo Salvarani, Luca Cantarini
The study aim was to evaluate the efficacy of adalimumab (ADA) in a large series of Behçet's disease (BD)-related uveitis. We performed a multicenter retrospective observational study including 40 selected patients (66 eyes) receiving ADA. Clinical data were retrospectively analyzed at baseline, at 3 and 12 months of treatment. Primary end point was reduction of ocular inflammatory flares. Secondary end points were improvement of best corrected visual acuity (BCVA), reduction of macular thickness measured by optical coherence tomography (OCT), reduction in the occurrence of vasculitis assessed by fluorescein angiography (FA), and evaluation of statistically significant differences between patients treated with ADA monotherapy and those undergoing ADA plus DMARDs and in patients firstly treated with ADA compared to patients previously administered with other biologics; ADA steroid sparing effect was also evaluated...
November 16, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27849401/looking-for-ocular-tuberculosis-prevalence-and-clinical-manifestations-of-patients-with-uveitis-and-positive-quantiferon-%C3%A2-tb-gold-test
#7
Kessara Pathanapitoon, Paradee Kunavisarut, Wasna Sirirungsi, Aniki Rothova
PURPOSE: To report on the prevalence of ocular TB and positive QuantiFERON(®)-TB Gold (QFT-G) test in uveitis patients and describe their clinical manifestations. METHODS: We performed a prospective study of 108 new human immunodeficiency virus-negative uveitis patients. All patients underwent a tailored screening protocol for uveitis and received QFT-G test and tuberculin skin tests (TST). RESULTS: QFT-G test was positive in 39/108 (36%) of patients, while TST ≥15 mm was positive in 16/108 (15%) patients...
November 16, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27847627/visual-response-and-anatomical-changes-on-sequential-spectral-domain-optical-coherence-tomography-in-birdshot-chorioretinopathy-treated-with-local-corticosteroid-therapy
#8
Marisa Gobuty, Mehreen Adhi, Sarah P Read, Jay S Duker
BACKGROUND: Birdshot chorioretinopathy is a chronic bilateral inflammatory disease of unknown etiology characterized by bilateral retinal vasculitis, mild to moderate vitritis, retinal vascular leakage, cystoid macular edema (CME), and typical "birdshot" chorioretinal lesions. Typically, patients with birdshot chorioretinopathy are treated with systemic immunosuppressive and/or corticosteroid therapy in an effort to minimize loss of vision. Spectral-domain OCT (SD-OCT) has shown regional or generalized photoreceptor loss in addition to both retinal as well as choroidal thinning in these patients...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27826182/amaurosis-fugax-risk-factors-and-prevalence-of-significant-carotid-stenosis
#9
Pia Kvickström, Bertil Lindblom, Göran Bergström, Madeleine Zetterberg
PURPOSE: The purpose of this study was to describe clinical characteristics and prevalence of carotid stenosis in patients with amaurosis fugax (AF). METHOD: Patients diagnosed with AF and subjected to carotid ultrasound in 2004-2010 in Sahlgrenska University Hospital, Gothenburg (n=302), were included, and data were retrospectively collected from medical records. RESULTS: The prevalence of significant carotid stenosis was 18.9%, and 14.2% of the subjects were subjected to carotid endarterectomy...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27820753/retinal-vasculitis-associated-with-neuromyelitis-optica
#10
Mikel Mikhail, Ayesha Khan
PURPOSE: To report a case of retinal vasculitis in a patient with neuromyelitis optica. METHODS: Clinical case report, imaging was obtained with photographs, fluorescein angiography, spectral domain optical coherence tomography, and magnetic resonance imaging. RESULTS: The aforementioned patient presented with urinary incontinence and spastic paraparesis. She was found to have a transverse myelitis on magnetic resonance imaging and positive anti-aquaporin-4 (AQP4-Ab) testing...
November 3, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27800257/peripheral-vasculitis-intermediate-uveitis-and-interferon-use-in-multiple-sclerosis
#11
Şeref Kinyas, Haluk Esgin
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. A 40-year-old female patient with a 12-year history of MS was admitted to our clinic with blurred vision and floaters in her right eye for about 1 month. Here, we share the findings and the management of intermediate uveitis and retinal periphlebitis in an MS case being treated with interferon beta-1a for 7 years.
January 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27771870/disseminated-nontuberculous-mycobacterial-infection-with-multifocal-retinitis-and-vasculitis-in-an-immunocompromised-patient-with-anti-ifn-%C3%A9-autoantibodies
#12
Tian Loon Lee, Rupesh Agrawal, Jackie Yu-Ling Tan, Kiat Hoe Ong, Chen Seong Wong, Su Ling Ho
BACKGROUND: Nontuberculous mycobacteria (NTM) are found ubiquitously in the environment. Since exposure to NTM is universal, infection likely represents underlying host susceptibility factors. Anti-IFN-ɣ autoantibodies have been described previously in patients with NTM. Up to 88 % of patients with disseminated NTM or other opportunistic infections have high-titer anti-IFN-ɣ autoantibodies, compared with 2 % of patients with TB and healthy controls. FINDINGS: We report a unique presentation of a patient with anti-IFN-ɣ autoantibodies with disseminated NTM infection who presents with panuveitis with multifocal retinitis and vasculitis...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27759582/microvascular-flow-abnormalities-associated-with-retinal-vasculitis-a-potential-of-mechanism-of-retinal-injury
#13
Richard F Spaide
PURPOSE: To investigate the structural optical coherence tomography and related microvascular flow characteristics in eyes with retinal vasculitis. METHODS: Regions involved with perivascular infiltration in eyes with retinal vasculitis, but no evidence of large vessel occlusion were evaluated with optical coherence tomography (OCT), OCT angiography, and fluorescein angiography. RESULTS: Ten eyes of 5 patients with a variety of etiologies of retinal vasculitis were evaluated...
October 18, 2016: Retina
https://www.readbyqxmd.com/read/27756269/acute-multifocal-hemorrhagic-retinal-vasculitis-in-a-child-a-case-report
#14
Malik Y Ghannam, Mohammed Naseemuddin, Peter Weiser, John O Mason
BACKGROUND: Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidence that presents with abrupt onset of visual loss associated with retinal vasculitis, retinal hemorrhage, non-confluent posterior retinal infiltrates, vitreous cellular inflammation and papillitis in, otherwise, healthy adult individuals. The reported treatment options for Acute Multifocal Hemorrhagic Retinal Vasculitis are oral corticosteroids, intravitreal ganciclovir and laser photocoagulation or vitrectomy...
October 18, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27726473/retinal-vasculitis-in-patients-with-systemic-lupus-erythematosus
#15
Mohammed El Amine Ghembaza, Ali Lounici
No abstract text is available yet for this article.
October 11, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27715380/ocular-manifestations-conventional-fundus-fluorescein-angiographic-findings-and-relationship-between-angiographic-findings-and-visual-acuity-in-beh%C3%A3-et-s-disease
#16
Fatemeh Bazvand, Mohammad Zarei, Nazanin Ebrahimiadib, Reza Karkhaneh, Samaneh Davoudi, Mahyar Soleimanzadeh, Elaheh Sharifian, Ramak Roohipoor, Bobeck S Modjtahedi
PURPOSE: Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behçet's disease as well as the relationship between visual acuity and angiographic findings. METHODS: Retrospective chart review of patients with Behçet's disease seen at the Farabi Eye Hospital. RESULTS: Forty-six patients (92 eyes) with mean age of 33.41 ± 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively...
August 10, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27631486/retinal-vasculitis-in-anti-synthetase-syndrome
#17
Christopher P Donovan, Paula E Pecen, Kimberly Baynes, Justis P Ehlers, Sunil K Srivastava
A 31-year-old woman with a history of anti-synthetase syndrome-related myositis and interstitial lung disease presented with acute-onset blurry vision and rash on her hands and feet. Visual acuity was hand motion in her right eye and 20/40 in her left eye. Dilated fundus exam showed extensive retinal vasculitis, diffuse intraretinal hemorrhages, and subretinal fluid. Optical coherence tomography revealed significant macular thickening, and fluorescein angiography revealed vascular leakage with peripheral nonperfusion...
September 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27577846/acute-retinal-necrosis-results-in-low-vision-in-a-young-patient-with-a-history-of-herpes-simplex-virus-encephalitis
#18
Sanjeet K Shahi
Acute retinal necrosis (ARN), secondary to herpes simplex encephalitis, is a rare syndrome that can present in healthy individuals, as well as immuno-compromised patients. Most cases are caused by a secondary infection from the herpes virus family, with varicella zoster virus being the leading cause of this syndrome. Potential symptoms include blurry vision, floaters, ocular pain and photophobia. Ocular findings may consist of severe uveitis, retinal vasculitis, retinal necrosis, papillitis and retinal detachment...
August 31, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27552119/hemorrhagic-occlusive-retinal-vasculitis-and-nonhemorrhagic-vasculitis-after-uncomplicated-cataract-surgery-with-intracameral-vancomycin
#19
David S Ehmann, Murtaza K Adam, Sundeep K Kasi, Arunan Sivalingam, James P Dunn
PURPOSE: To describe two cases of vasculitis: one hemorrhagic and one nonhemorrhagic after uncomplicated cataract surgery with intracameral vancomycin. METHODS: Retrospective case series. RESULTS: A 74-year-old female and a 54-year-old female developed severe visual loss within 2 weeks of uncomplicated cataract surgery with intracameral vancomycin. The first patient developed a fulminant hemorrhagic vasculitis, whereas the second patient developed a less severe nonhemorrhagic vasculitis...
August 22, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27548454/hemorrhagic-occlusive-retinal-vasculitis-after-first-eye-cataract-surgery-without-subsequent-second-eye-involvement
#20
Nicole Balducci, Giacomo Savini, Piero Barboni, Pietro Ducoli, Antonio Ciardella
A case of monocular postoperative hemorrhagic occlusive retinal vasculitis (HORV) after uncomplicated bilateral cataract surgery is described. HORV is a severe syndrome that leads to painless visual loss after uncomplicated cataract surgery. The same surgical procedure was adopted in both eyes except for the use of intracameral vancomycin, which was injected only in the eye that developed HORV. Diffuse retinal ischemia with vascular sheathing and intraretinal hemorrhages were detected during the fourth postoperative day...
August 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
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