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retinal vasculitis

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https://www.readbyqxmd.com/read/29122311/-uveitis-diagnostic-work-up-recommendations-from-an-expert-committee
#1
P Sève, B Bodaghi, S Trad, J Sellam, D Bellocq, P Bielefeld, D Sène, G Kaplanski, D Monnet, A Brézin, M Weber, D Saadoun, P Cacoub, C Chiquet, L Kodjikian
INTRODUCTION: Diagnostic work-up of uveitis involves many uncertainties. Search for an etiology should take into account the epidemiology of uveitis and focus on the most severe diseases or those, which can be treated. This work was undertaken to establish recommendations for the diagnosis work-up of uveitis. METHODS: Recommendations were developed by a multidisciplinary panel of 15 experts, including internists, ophthalmologists and a rheumatologist and are based on a review of the literature with regard to effectiveness of investigations and the results of the ULISSE study, which is the first prospective study assessing the efficiency of a standardized strategy for the etiological diagnosis of uveitis...
November 6, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29121367/idiopathic-retinal-vasculitis-aneurysms-and-neuroretinitis-syndrome-presenting-with-branch-retinal-artery-occlusion
#2
Jennifer A Zacharia, Adam T Chin, Carl B Rebhun, Ricardo N Louzada, Mehreen Adhi, Emily D Cole, Carlos Moreira-Neto, Nadia K Waheed, Jay S Duker
Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) is a rare syndrome affecting the retinal and optic disc vasculature. Diffuse retinal ischemia, macular edema, and neovascularization may lead to bilateral vision loss. The authors report a case of a 36-year-old woman presenting with branch retinal artery occlusion (BRAO) in her right eye who was subsequently diagnosed with IRVAN syndrome. She was treated with panretinal photocoagulation for peripheral retinal ischemia and pars plana vitrectomy for vitreous hemorrhage...
November 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29110127/-atypical-retinal-vasculitis
#3
A William, C Rössler, C Binder
No abstract text is available yet for this article.
November 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29095716/intracameral-antibiotics-during-cataract-surgery-evidence-and-barriers
#4
Aravind Haripriya, David F Chang
PURPOSE OF REVIEW: There is continuing debate regarding the safety, efficacy, and necessity of intracameral antibiotics to prevent postoperative endophthalmitis. We summarize the most recent evidence-based publications that either support or caution against this practice. RECENT FINDINGS: Several additional large, international retrospective clinical studies found a significant reduction in endophthalmitis rates with intracameral antibiotic prophylaxis. Many surgeons are looking for alternatives to vancomycin for intracameral prophylaxis because of its association with the rare but sight-threatening complication of hemorrhagic occlusive retinal vasculitis...
October 31, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29075752/clinical-features-and-outcomes-of-patients-with-tubercular-uveitis-treated-with-antitubercular-therapy-in-the-collaborative-ocular-tuberculosis-study-cots-1
#5
Rupesh Agrawal, Dinesh Visva Gunasekeran, Robert Grant, Aniruddha Agarwal, Onn Min Kon, Quan Dong Nguyen, Carlos Pavesio, Vishali Gupta
Importance: Eradication of systemic tuberculosis (TB) has been limited by neglected populations and the HIV pandemic. Whereas ocular TB often presents as uveitis without any prior evidence of systemic TB, the existing uncertainty in the diagnosis of TB uveitis may perpetuate missed opportunities to address systemic TB. Objective: To examine the clinical features of TB uveitis and the associations with response to antitubercular therapy (ATT). Design, Setting, and Participants: This retrospective multinational cohort study included patients from 25 ophthalmology referral centers diagnosed with TB uveitis and treated with ATT from January 1, 2004, through December 31, 2014, with a minimum follow-up of 1 year...
October 26, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29069031/clinical-manifestations-and-treatment-outcomes-of-syphilitic-uveitis-in-hiv-negative-patients-in-china-a-retrospective-case-study
#6
Jiang Zhu, Yuan Jiang, Yewen Shi, Bo Zheng, Zhiguo Xu, Wei Jia
Syphilitic chorioretinitis should be included in differential diagnosis of any form of ocular inflammation. A significantly higher proportion of human immunodeficiency virus (HIV)-positive patients with ocular syphilis as compared to HIV-negative cases have been reported in published studies. However, the clinical signs and symptoms are more insidious in HIV-negative patients who are easily misdiagnosed. We report a series of cases of ocular syphilis and describe the clinical manifestations and treatment outcomes of syphilitic chorioretinitis in HIV-negative patients in China...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29062788/intravitreal-bevacizumab-in-treatment-of-retinal-neovascularization-from-tuberculous-retinal-vasculitis
#7
Theeratach Sriboonnark, Sutasinee Boonsopon, Nattaporn Tesavibul, Supinda Leeamornsiri, Pitipol Choopong
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29062224/idiopathic-retinal-vasculitis-aneurysms-and-neuroretinitis-irvan-syndrome-clinical-perspectives
#8
REVIEW
Priya Bajgai, Deeksha Katoch, Mangat Ram Dogra, Ramandeep Singh
Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome typically affects young, healthy individuals. Despite the dramatic fundus appearance seen in this syndrome, these patients are usually asymptomatic. The syndrome includes peculiar vascular abnormalities in the form of multiple aneurysmal dilatations seen along retinal arterioles and optic nerve-head arterioles, which are best appreciated on fluorescein angiography. Neuroretinitis and retinal vasculitis are seen in all patients, and manifested by staining of the optic nerve head and diffuse leakage from vessels, mainly arterioles, on fluorescein angiography...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29059086/rituximab-for-sight-threatening-lupus-related-retinal-vasculitis
#9
Konstantinos Tselios, Wai-Ching Lam, Murray B Urowitz, Dafna D Gladman
No abstract text is available yet for this article.
October 20, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29054905/ultra-wide-imaging-in-a-case-of-retinal-vasculitis-with-macular-star
#10
Abhishek Sheemar, Brijesh Takkar, Shreyas Temkar, Pradeep Venkatesh
No abstract text is available yet for this article.
October 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29037906/uveitis-diagnostic-work-up-a-literature-review-and-recommendations-from-an-expert-committee
#11
REVIEW
Pascal Sève, Patrice Cacoub, Bahram Bodaghi, Salim Trad, Jérémie Sellam, David Bellocq, Philip Bielefeld, Damien Sène, Gilles Kaplanski, Dominique Monnet, Antoine Brézin, Michel Weber, David Saadoun, Christophe Chiquet, Laurent Kodjikian
PURPOSE: Diagnosis of uveitis is difficult. Etiologic investigations should take into account the epidemiology of uveitis and should focus on the most severe forms of the disease and those which can be treated. This study was undertaken to establish recommendations for the diagnosis of uveitis. METHODS: Recommendations were developed by a multidisciplinary panel of 14 experts, including internists, ophthalmologists, and rheumatologists, and are based on a review of the literature and the results of the ULISSE study, which was the first prospective study to assess the efficacy of a standardized strategy for the etiologic diagnosis of uveitis...
October 14, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29027603/review-of-people-with-retinal-vasculitis-and-positive-quantiferon-%C3%A2-tb-gold-test-in-an-area-nonendemic-for-tuberculosis
#12
David R Brunner, Sandrine A Zweifel, Daniel Barthelmes, Fabio Meier, Christian Böni
PURPOSE: To assess the frequency of a positive QuantiFERON(®)-TB Gold test (quantiferon) among patients with retinal vasculitis in an area nonendemic for tuberculosis (TB); to review clinical characteristics and management of affected individuals. METHODS: Consecutive patients with retinal vasculitis and a positive quantiferon were retrospectively analyzed. Demographics, clinical data, laboratory, imaging findings, and therapy were evaluated. RESULTS: Among 49 patients with retinal vasculitis, 12 (24%) had a positive quantiferon...
October 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29020486/ocular-manifestations-and-visual-outcomes-of-beh%C3%A3-et-s-uveitis-in-a-thai-population
#13
Kessara Pathanapitoon, Paradee Kunavisarut, Fa-Arun Saravuttikul, Aniki Rothova
PURPOSE: To report on ocular manifestations and visual outcomes of Thai patients with Behçet's Uveitis (BU). METHODS: We reviewed medical records of 50 BU patients (31 males and 19 females). Ocular manifestations, treatment modalities, complications, and visual outcomes were registered. RESULTS: Ocular involvement was bilateral in 76% of patients, resulting in 89 affected eyes. Panuveitis and posterior uveitis were the most common types. Retinal vasculitis was noted in majority of affected eyes and specifically arteritis was noticed in 32/57(56%)...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29016525/paracentral-acute-middle-maculopathy-in-susac-syndrome
#14
Ali S Haider, Deepa Viswanathan, David Williams, Peter Davies
PURPOSE: To present the first reported case of paracentral acute middle maculopathy in association with Susac syndrome. METHOD: Case report. RESULTS: A young female patient presented with unilateral sudden loss of vision of her right eye to count fingers. There were numerous cotton wool spots in a multifocal pattern concentrated around the right macula and optic disk. Clinical examination and spectral domain optical coherence tomography imaging were consistent with paracentral acute middle maculopathy, and fluorescein angiography showed features of retinal arteriole vasculitis...
October 9, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28981395/rapid-and-sustained-efficacy-of-golimumab-in-the-treatment-of-multirefractory-uveitis-associated-with-beh%C3%A3-et-s-disease
#15
Claudia Fabiani, Jurgen Sota, Donato Rigante, Antonio Vitale, Giacomo Emmi, Lorenzo Vannozzi, Rossella Franceschini, Daniela Bacherini, Bruno Frediani, Mauro Galeazzi, Gian Marco Tosi, Luca Cantarini
PURPOSE: To evaluate golimumab (GOL) efficacy in the management of Behçet's disease (BD)-related uveitis. METHODS: We retrospectively collected data from 5 patients (8 eyes) with at least two recent relapses of uveitis, treated with GOL at the standard dose of 50 mg every 4 weeks. RESULTS: A complete control of intraocular inflammation was observed in 7/8 eyes (87.5%) at 12-month follow-up. The number of relapses 12 months before and after GOL initiation was 11 and 1, respectively...
October 5, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28969754/cytomegalovirus-retinitis-in-immunocompetent-young-male
#16
Eijaz Ghani, Misbah Noor, Saadiya Khalid
Cytomegalovirus (CMV) retinitis is a sight-threatening form of posterior uveitis affecting patients with Acquired Immunodeficiency Syndrome (AIDS), especially those with CD4 count <50 cells/mm3. There are few reported cases of CMV retinitis in patients with CD4 count >100 cells/mm3. Avirostatic agent like Ganciclovir has good response rate when given as intravitreal injection. Here, we report a case of CMV retinitis in a young immunocompetent male who presented with history of progressive loss of vision in both eyes despite receiving oral and intra-vitreal steroids...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28937479/retinal-vasculitis-and-choroidopathy-in-pediatric-onset-mixed-connective-tissue-disease
#17
Bradley Postlethwaite, Henry G Wynn, Debendra Pattanaik, Shelley Ost, Charles B MacDonald, R Christopher Walton, Seunghyun Kim, Linda K Myers, Monica Brown Lobbins
No abstract text is available yet for this article.
October 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28936058/multifocal-choroiditis-with-retinal-vasculitis-optic-neuropathy-and-keratoconus-in-a-young-saudi-male
#18
Yousef Dhafiri, Khalid Al Rubaie, Omar Kirat, William N May, Quan D Nguyen, Igor Kozak
The purpose of this study is to describe an association of unilateral multifocal choroiditis (MFC), retinal vasculitis, optic neuropathy, and bilateral keratoconus in a young Saudi male. A 27-year-old male patient with stable bilateral keratoconus presented with a painless vision loss in his left eye. Ophthalmic examinations revealed multiple foci of idiopathic chorioretinitis, retinal vasculitis, and mild optic disc leakage on fluorescein angiography, all of which resolved on systemic therapy with mycophenolate mofetil and prednisone after 3 months...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28919362/a-homozygote-trex1-mutation-in-two-siblings-with-different-phenotypes-chilblains-and-cerebral-vasculitis
#19
Rabia Miray Kisla Ekinci, Sibel Balci, Atil Bisgin, Derya Ufuk Altintas, Mustafa Yilmaz
Three prime repair exonuclease 1 degrades single and double stranded DNA with 3'-5' nuclease activity and its mutations are related to type 1 IFN mediated autoinflammation due to accumulated intracellular nucleic acids. To date, several cases of systemic lupus erythematosus, Aicardi-Goutieres syndrome, familial chilblain lupus, retinal vasculopathy-cerebral leukodystrophy have been reported with TREX1 mutations. Chilblain lupus is a skin disease characterized by blue-reddish coloring, swelling or ulcers on acral regions of body such as fingertips, heels, nose and auricles...
September 13, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28901810/the-incidence-of-ocular-tuberculosis-in-australia-over-the-past-10-years-2006-2015
#20
Erica Darian-Smith, Ming-Lee Lin, Lyndell L Lim, Peter McCluskey, Anthony J Hall
PURPOSE: To determine the incidence and clinical phenotype of ocular tuberculosis in Australia based on the mandatory jurisdictional health notification records for TB. METHODS: A whole population retrospective case series (Australia). Patients diagnosed with ocular tuberculosis were identified over the past 10 years (1 January 2006 to 31 December 2015) as recorded by individual Health Department jurisdictions per mandatory health notifications. The incidence rates were calculated based on the available Australian census data...
September 13, 2017: Ophthalmic Epidemiology
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