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https://www.readbyqxmd.com/read/28691693/influence-of-physico-mechanical-properties-of-elastomeric-material-for-different-cell-growth
#1
Jyoti Wala, Debashis Maji, Soumen Das
The tunable mechanical and physical properties of Polydimethylsiloxane (PDMS) are commonly utilized for studying cellular dynamics. However, the inherent hydrophobic nature of PDMS limits its application as cell culture films. Various surface modification techniques render PDMS films hydrophilic which alters the surface chemistry, elasticity, roughness and cell attachment of anchorage dependent cell types to the films. The surface properties of thin film lead to alteration in bio-mechano-physical properties of cells and therefore could be used as mechanical signature for viability testing of different normal and cancerous cells...
July 10, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28691142/force-level-of-small-diameter-nickel-titanium-orthodontic-wires-ligated-with-different-methods
#2
Rodrigo Hitoshi Higa, José Fernando Castanha Henriques, Guilherme Janson, Murilo Matias, Karina Maria Salvatore de Freitas, Fernanda Pinelli Henriques, Manoela Fávaro Francisconi
BACKGROUND: The aim of this study was to compare the deflection force in conventional and thermally activated nickel-titanium (NiTi) wires in passive (Damon Q) and active (Bioquick) self-ligating brackets (SLB) and in conventional brackets (CB) tied by two different methods: elastomeric ligature (EL) and metal ligature (ML). METHODS: Two wire diameters (0.014 and 0.016 in.) and 10 specimens per group were used. The specimens were assembled in a clinical simulation device and tested in an Instron Universal Testing Machine, with a load cell of 10 N...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28678968/evaluation-of-deflection-forces-of-orthodontic-wires-with-different-ligation-types
#3
José Fernando Castanha Henriques, Rodrigo Hitoshi Higa, Nayara Thiago Semenara, Guilherme Janson, Thais Maria Freire Fernandes, Renata Sathler
The aim of this study was to evaluate deflection forces of orthodontic wires of different alloys engaged into conventional brackets using several ligation types. Stainless steel, conventional superelastic nickel-titanium and thermally activated nickel-titanium archwires tied into conventional brackets by a ring-shaped elastomeric ligature (RSEL), a 8-shaped elastomeric ligature (8SEL) and a metal ligature (ML) were tested. A clinical simulation device was created especially for this study and forces were measured with an Instron Universal Testing Machine...
July 3, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28647645/adding-dimension-to-cellular-mechanotransduction-advances-in-biomedical-engineering-of-multiaxial-cell-stretch-systems-and-their-application-to-cardiovascular-biomechanics-and-mechano-signaling
#4
REVIEW
O Friedrich, D Schneidereit, Y A Nikolaev, V Nikolova-Krstevski, S Schürmann, A Wirth-Hücking, A L Merten, D Fatkin, B Martinac
Hollow organs (e.g. heart) experience pressure-induced mechanical wall stress sensed by molecular mechano-biosensors, including mechanosensitive ion channels, to translate into intracellular signaling. For direct mechanistic studies, stretch devices to apply defined extensions to cells adhered to elastomeric membranes have stimulated mechanotransduction research. However, most engineered systems only exploit unilateral cellular stretch. In addition, it is often taken for granted that stretch applied by hardware translates 1:1 to the cell membrane...
June 21, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28645997/temperature-profiles-of-antibiotic-containing-elastomeric-infusion-devices-used-by-ambulatory-care-patients
#5
Toni Docherty, Michael Montalto, Joni Leslie, Katrina King, Suzanne Niblett, Tim Garrett
PURPOSE: The temperature profiles of antibiotic-containing elastomeric infusion devices used by ambulatory care patients under various environmental conditions were evaluated. METHODS: A prospective, descriptive survey of temperature exposure was conducted in 4 publically funded hospitals. Over a 12-month period, electronic temperature-recording devices were attached to the antibiotic infusion devices (infusers) of prospectively randomized hospital-in-the-home (HITH) participants...
July 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28634955/human-lung-small-airway-on-a-chip-protocol
#6
Kambez H Benam, Marc Mazur, Youngjae Choe, Thomas C Ferrante, Richard Novak, Donald E Ingber
Organs-on-chips are microfluidic cell culture devices created using microchip manufacturing techniques that contain hollow microchannels lined by living cells, which recreate specialized tissue-tissue interfaces, physical microenvironments, and vascular perfusion necessary to recapitulate organ-level physiology in vitro. Here we describe a protocol for fabrication, culture, and operation of a human lung "small airway-on-a-chip," which contains a differentiated, mucociliary bronchiolar epithelium exposed to air and an underlying microvascular endothelium that experiences fluid flow...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28623642/particle-spallation-in-a-microfluidic-blood-processing-device-the-problem-of-using-peristaltic-pumps-and-silicon-based-microfilters
#7
Monica Faria, Yi Liu, Edward F Leonard
Peristaltic pumps rely on constant compression of elastomeric tubing from which particles may be shed, a phenomenon known as spallation. We studied spallated particles on microfluidic filtration devices with photolithographically prepared micron-level pore fields. Filtration of ultra-pure water through these pores was analyzed using either the usual peristaltic pump or a reciprocating pair of syringe pumps. Using syringe pumps, transmembrane pressure (TMP) values during filtration at 2.5 cm3/min revealed steady filtration for over 80 minutes at 2...
June 15, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28620970/a-coating-free-nonfouling-polymeric-elastomer
#8
Hsiang-Chieh Hung, Priyesh Jain, Peng Zhang, Fang Sun, Andrew Sinclair, Tao Bai, Bowen Li, Kan Wu, Caroline Tsao, Erik J Liu, Harihara S Sundaram, Xiaojie Lin, Payam Farahani, Timothy Fujihara, Shaoyi Jiang
Medical devices face nonspecific biofouling from proteins, cells, and microorganisms, which significantly contributes to complications and device failure. Imparting these devices with nonfouling capabilities remains a major challenge, particularly for those made from elastomeric polymers. Current strategies, including surface coating and copolymerization/physical blending, necessitate compromise among nonfouling properties, durability, and mechanical strength. Here, a new strategy is reported to achieve both high bulk mechanical strength and excellent surface nonfouling properties, which are typically contradictory, in one material...
June 16, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28576717/transient-phase-behavior-of-an-elastomeric-biomaterial-applied-to-abdominal-laparotomy-closure
#9
Omer E Kaymakcalan, Julia L Jin, Zhexun Sun, Nicole G Ricapito, Mary Clare McCorry, Kerry A Morrison, David Putnam, Jason A Spector
Secure closure of the fascial layers after entry into the peritoneal cavity is crucial to prevent incisional hernia, yet appropriate purchase of the tissue can be challenging because of the proximity of the underlying protuberant bowel which may become punctured by the surgical needle or strangulated by the suture itself. Whereas currently employed devices, the metal malleable retractor and Glassman Visceral Retainer are unable to provide complete visceral protection during abdominal closure, a puncture resistant, biocompatible, and degradable matrix that can be left in place without need for removal would facilitate rapid and safe abdominal closure...
May 30, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28535341/fully-stretchable-optoelectronic-sensors-based-on-colloidal-quantum-dots-for-sensing-photoplethysmographic-signals
#10
Tae-Ho Kim, Chang-Seok Lee, Sangwon Kim, Jaehyun Hur, Sangmin Lee, Keun Wook Shin, Young-Zoon Yoon, Moon Kee Choi, Jiwoong Yang, Dae-Hyeong Kim, Taeghwan Hyeon, Seongjun Park, Sungwoo Hwang
Flexible and stretchable optoelectronic devices can be potentially applied in displays, biosensors, biomedicine, robotics, and energy generation. The use of nanomaterials with superior optical properties such as quantum dots (QDs) is important in the realization of wearable displays and biomedical devices, but specific structural design as well as selection of materials should preferentially accompany this technology to realize stretchable forms of these devices. Here, we report stretchable optoelectronic sensors manufactured using colloidal QDs and integrated with elastomeric substrates, whose optoelectronic properties are stable under various deformations...
June 27, 2017: ACS Nano
https://www.readbyqxmd.com/read/28524191/thermal-scribing-to-prototype-plastic-microfluidic-devices-applied-to-study-the-formation-of-neutrophil-extracellular-traps
#11
Arvind Chandrasekaran, Nikita Kalashnikov, Roni Rayes, Claire Wang, Jonathan Spicer, Christopher Moraes
Innovation in microfluidics-based biological research has been aided by the growing accessibility of versatile microscale fabrication techniques, particularly in rapid prototyping of elastomeric polydimethylsiloxane (PDMS) based devices. However, the use of PDMS presents considerable and often unexpected limitations, particularly in interpreting and validating biological data. To rapidly prototype microfluidic culture systems in conventional plastics commonly used in cell culture, we developed 'thermal scribing', a one-step micromachining technique in which thermoplastics are locally patterned by a heated tip, moving in user-controlled patterns...
May 31, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28523760/bioinspired-composite-microfibers-for-skin-adhesion-and-signal-amplification-of-wearable-sensors
#12
Dirk-M Drotlef, Morteza Amjadi, Muhammad Yunusa, Metin Sitti
A facile approach is proposed for superior conformation and adhesion of wearable sensors to dry and wet skin. Bioinspired skin-adhesive films are composed of elastomeric microfibers decorated with conformal and mushroom-shaped vinylsiloxane tips. Strong skin adhesion is achieved by crosslinking the viscous vinylsiloxane tips directly on the skin surface. Furthermore, composite microfibrillar adhesive films possess a high adhesion strength of 18 kPa due to the excellent shape adaptation of the vinylsiloxane tips to the multiscale roughness of the skin...
May 19, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28512333/hybrid-organic-tandem-solar-cell-comprising-small-molecule-bottom-and-polymer-fullerene-top-subcells-fabricated-by-thin-film-transfer
#13
Yoonseok Ka, Hyejin Hwang, Changsoon Kim
Multilayer structures involving solution-deposited polymer films are difficult to fabricate, not allowing for unrestricted designs of polymer-based optoelectronic devices required for maximizing their performance. Here, we fabricate a hybrid organic tandem solar cell whose top and bottom subcells have polymer:fullerene and small molecules active layers, respectively, by a solvent-free process based on transferring the polymer:fullerene layer from an elastomeric stamp onto a vacuum-deposited bottom subcell. The interface between small-molecule and transferred polymer:fullerene layers is void-free at the nanoscale, allowing for efficient charge transport across the interface...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28485567/stretchable-transparent-and-stretch-unresponsive-capacitive-touch-sensor-array-with-selectively-patterned-silver-nanowires-reduced-graphene-oxide-electrodes
#14
Tae Young Choi, Byeong-Ung Hwang, Bo-Yeong Kim, Tran Quang Trung, Yun Hyoung Nam, Do-Nyun Kim, Kilho Eom, Nae-Eung Lee
Stretchable and transparent touch sensors are essential input devices for future stretchable transparent electronics. Capacitive touch sensors with a simple structure of only two electrodes and one dielectric are an established technology in current rigid electronics. However, the development of stretchable and transparent capacitive touch sensors has been limited due to changes in capacitance resulting from dimensional changes in elastomeric dielectrics and difficulty in obtaining stretchable transparent electrodes that are stable under large strains...
May 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28441503/robust-uniform-and-highly-emissive-quantum-dot-polymer-films-and-patterns-using-thiol-ene-chemistry
#15
Marcus J Smith, Sidney T Malak, Jaehan Jung, Young Jun Yoon, Chun Hao Lin, Sunghan Kim, Kyung Min Lee, Ruilong Ma, Timothy J White, Timothy J Bunning, Zhiqun Lin, Vladimir V Tsukruk
This work demonstrates a facile and versatile method for generating low scattering cross-linked quantum dot (QD)-polymer composite films and patterned highly emissive structures with ultrahigh QD loading, minimal phase separation, and tunable mechanical properties. Uniform QD-polymer films are fabricated using thiol-ene chemistry, in which cross-linked polymer networks are rapidly produced in ambient conditions via fast UV polymerization in bulk to suppress QD aggregation. UV-controlled thiol-ene chemistry limits phase separation through producing highly QD loaded cross-linked composites with loadings above majority of those reported in the literature (<1%) and approaching 30%...
May 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28415424/development-of-strong-biodegradable-and-highly-elastomeric-polycitrate-gelatin-hybrid-polymer-with-enhanced-cellular-biocompatibility
#16
Caiting Feng, Yuzhang Du, Yannan Li, Bo Lei
Native human tissues possess incomparable biological performance due to their strong and viscoelastic mechanical properties, and biocompatible compositions. Herein, by a thermal polymerization and solvent hybridization method, we develop biomimetic polycitrate-gelatin hybrid polymers (PC-GT) with strong mechanical properties and tailored elastomeric behavior for tissue regeneration applications. The incorporation of gelatin significantly enhanced the mechanical properties and cellular biocompatibility of PC...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28357823/performance-of-the-bbraun-perfusor-space-syringe-driver-under-hyperbaric-conditions
#17
Lachlan Frawley, Bridget Devaney, Theo Tsouras, Geoff Frawley
BACKGROUND: The BBraun Perfusor Space™ syringe driver is already in use by ambulance services and retrieval teams but has not previously been assessed for hyperbaric chamber use. METHODS: Pump flow accuracy was tested at rates between 1 and 40 ml· h⁻¹ using three different brands of 50 ml syringe. Function of the occlusion alarms was assessed using the same syringes. The hyperbaric profile involved pressurisation to 284 kPa at 30 kPa· min⁻¹, 30 min at 284 kPa and decompression at 30 kPa· min⁻¹...
March 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28357822/an-assessment-of-the-performance-of-the-baxter-elastomeric-lv10-infusor%C3%A2-pump-under-hyperbaric-conditions
#18
Stephen Perks, Denise F Blake, Derelle A Young, John Hardman, Lawrence H Brown, Iestyn Lewis, Tilley Pain
INTRODUCTION: There are limited data on the use of elastomeric infusion pumps during hyperbaric oxygen treatment. AIM: This study evaluated the flow rate of the Baxter elastomeric LV10 Infusor™ pump under normobaric (101.3 kPa) and three hyperbaric conditions of 203 kPa, 243 kPa and 284 kPa. METHODS: Elastomeric pumps were secured to participants in the same manner as for a typical patient, except that a container collected the delivered antibiotic solution...
March 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28338313/ultimate-control-of-rate-dependent-adhesion-for-reversible-transfer-process-via-a-thin-elastomeric-layer
#19
Chan Kim, Min-Ah Yoon, Bongkyun Jang, Jae-Hyun Kim, Hak-Joo Lee, Kwang-Seop Kim
Adhesion between a stamp with an elastomeric layer and various devices or substrates is crucial to successfully fabricate flexible electronics using a transfer process. Although various transfer processes using stamps with different adhesion strengths have been suggested, the controllable range of adhesion is still limited to a narrow range. To precisely transfer devices onto selected substrates, however, the difference in adhesion between the picking and placing processes should be large enough to achieve a high yield...
March 30, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28276240/biaxial-stretchability-and-transparency-of-ag-nanowire-2d-mass-spring-networks-prepared-by-floating-compression
#20
Byoung Soo Kim, Jun Beom Pyo, Jeong Gon Son, Goangseup Zi, Sang-Soo Lee, Jong Hyuk Park, Jonghwi Lee
Networks of silver nanowires (Ag NWs) have been considered as promising materials for stretchable and transparent conductors. Despite various improvements of their optoelectronic and electromechanical properties over the past few years, Ag NW networks with a sufficient stretchability in multiple directions that is essential for the accommodation of the multidirectional strains of human movement have seldom been reported. For this paper, biaxially stretchable, transparent conductors were developed based on 2D mass-spring networks of wavy Ag NWs...
March 29, 2017: ACS Applied Materials & Interfaces
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