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https://www.readbyqxmd.com/read/29733288/low-temperature-variation-of-acoustic-velocity-in-pdms-for-high-frequency-applications
#1
Jeremy Streque, Didier Rouxel, Abdelkrim Talbi, Matthieu Thomassey, Brice Vincent
Polydimethylsiloxane (PDMS) and other related silicon-based polymers are among the most widely employed elastomeric materials in microsystems, owing to their physical and chemical properties. Meanwhile, surface acoustic wave (SAW) and bulk acoustic wave (BAW) sensors and filters have been vastly explored for sensing and wireless applications. Many fields could benefit from the combined use of acoustic wave devices, and polydimethylsiloxane-based soft-substrates, microsystems, or packaging elements. The mechanical constants of PDMS strongly depend on frequency, similar to rubber materials...
May 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29708554/reconfigurable-microfluidic-channel-with-pin-discretized-sidewalls
#2
Nobuyuki Futai, Kenji Fujita, Wataru Ikuta
Microfluidic components need to have various shapes to realize different key microfluidic functions such as mixing, separation, particle trapping, or reactions. A microfluidic channel that deforms even after fabrication while retaining the channel shape enables high spatiotemporal reconfigurability. This reconfigurability is required in such key microfluidic functions that are difficult to achieve in existing "reconfigurable" or "integrated" microfluidic systems. We describe a method for the fabrication of a microfluidic channel with a deformable sidewall consisting of a laterally aligned array of the ends of rectangular pins...
April 12, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29700337/nanofabrication-of-conductive-metallic-structures-on-elastomeric-materials
#3
Edward K W Tan, Girish Rughoobur, Juan Rubio-Lara, Nikhil Tiwale, Zhuocong Xiao, Colin A B Davidson, Christopher R Lowe, Luigi G Occhipinti
Existing techniques for patterning metallic structures on elastomers are limited in terms of resolution, yield and scalability. The primary constraint is the incompatibility of their physical properties with conventional cleanroom techniques. We demonstrate a reliable fabrication strategy to transfer high resolution metallic structures of <500 nm in dimension on elastomers. The proposed method consists of producing a metallic pattern using conventional lithographic techniques on silicon coated with a thin sacrificial aluminium layer...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29697505/device-related-error-in-patient-controlled-analgesia-analysis-of-82-698-patients-in-a-tertiary-hospital
#4
Hyo-Jung Son, Sung-Hoon Kim, Jeong-Ok Ryu, Mi-Ra Kang, Myeong-Hee Kim, Jeong-Hun Suh, Jai-Hyun Hwang
BACKGROUND: Patient-controlled analgesia (PCA) is one of the most popular and effective methods for managing postoperative pain. Various types of continuous infusion pumps are available for the safe and accurate administration of analgesic drugs. Here we report the causes and clinical outcomes of device-related errors in PCA. METHODS: Clinical records from January 1, 2011 to December 31, 2014 were collected by acute pain service team nurses in a 2715-bed tertiary hospital...
April 23, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29682898/crumpling-and-unfolding-of-montmorillonite-hybrid-nanocoatings-as-stretchable-flame-retardant-skin
#5
Ting-Hsiang Chang, Yuan Tian, Daniel L Y Wee, Hongliang Ren, Po-Yen Chen
Flame-retardant coatings are widely used in a variety of personnel or product protection, and many applications would benefit from film stretchability if suitable materials are available. It is challenging to develop flame-retardant coatings that are stretchable, eco-friendly, and capable of being integrated on mechanically dynamic devices. Here, a concept is reported that uses pretextured montmorillonite (MMT) hybrid nanocoatings that can undergo programed unfolding to mimic the stretchability of elastomeric materials...
April 22, 2018: Small
https://www.readbyqxmd.com/read/29665978/outpatient-intravenous-multimodal-elastomeric-pump-with-methadone-in-ambulatory-surgery
#6
L Gómez-López, X Sala-Blanch, P L Gambús Cerrillo, A López Gutiérrez, M Agustí Lasús, M T Anglada Casas
BACKGROUND AND OBJECTIVE: Analgesia in Ambulatory Surgery (AS) needs to evolve in parallel with surgical complexity. We designed a study to try to improve analgesia in painful surgery using an intravenous elastomeric pump. As a novelty, methadone was included. PATIENTS AND METHODS: An observational study, physical status ASA I-II, underwent ambulatory surgeries with moderate-severe postoperative pain. Analgesia was administered for 48h by an intravenous multimodal elastomeric pump (methadone, tramadol, dexketoprofen and ondansetron at low doses)...
April 14, 2018: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/29628601/i-gel%C3%A2-may-be-the-device-of-choice-for-controlled-ventilation-in-patients-with-hemophilia-undergoing-abdominal-laparoscopic-surgery
#7
Sreyashi Sen, Koel Mitra, Shanta Ganguli, Sudakshina Mukherji
Haemophilia is an inherited bleeding disorder with variable deficiency of Factor VIII in the plasma and is characterised by bleeding into joints, muscles and tissues either spontaneously or in response to trivial trauma. Perioperative care requires multidisciplinary involvement. Perioperative management involves the risk of excessive bleeding from surgical site as well as spontaneous bleeding into the brain in response to surgical stress in patients with previous history of intracerebral haemorrhage. Airway management of such patients during anaesthetic intervention is a challenge and entails the risk of life threatening haemorrhage into the airway...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29624759/recent-advances-in-liquid-metal-manipulation-toward-soft-robotics-and-biotechnologies
#8
Yue Yu, Eijiro Miyako
Interest has grown significantly in the field of soft robotics, which seeks to develop machinery capable of duplicating the elastic and rheological properties of typically polymeric or elastomeric biological tissues and organs. As a result of a number of unique properties, gallium-based liquid metals (LMs) are emerging as materials used in the forefront of soft robotics research. Finding methods to enable the sophisticated manipulation of LMs will be essential for further progress in the field. This review provides a critical discussion of the manipulation of LMs and on important biotechnological applications of LMs including microfluidics, healthcare devices, biomaterials, and nanomedicines...
April 6, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29613971/the-impact-of-pediatric-outpatient-parenteral-antibiotic-therapy-implementation-at-a-tertiary-children-s-hospital-in-the-united-kingdom
#9
Sanjay Patel, Valentina Burzio, Helen Green, Sara Rees, Marc Tebruegge, Christine Jones, Saul N Faust
BACKGROUND: Recent advances in outpatient parenteral antibiotic therapy (OPAT) have largely focused on adult practice, and there are few published data on the safety and effectiveness of pediatric OPAT (p-OPAT). METHODS: During a 3-year-period (2012 to 2015), data were prospectively collected on patients managed within the p-OPAT service at Southampton Children's Hospital, a tertiary pediatric hospital in the South of England. RESULTS: A total of 130 p-OPAT episodes were managed during this period...
April 2, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29611242/porous-graphene-films-with-unprecedented-elastomeric-scaffold-like-folding-behavior-for-foldable-energy-storage-devices
#10
Ruling Huang, Meiling Huang, Xiaofeng Li, Fei An, Nikhil Koratkar, Zhong-Zhen Yu
The development of fully foldable energy storage devices is a major science and engineering challenge, but one that must be overcome if next-generation foldable or wearable electronic devices are to be realized. To overcome this challenge, it is necessary to develop new electrically conductive materials that exhibit superflexibility and can be folded or crumpled without plastic deformation or damage. Herein, a graphene film with engineered microvoids is prepared by reduction (under confinement) of its precursor graphene oxide film...
April 2, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29605992/electroluminescent-pressure-sensing-displays
#11
Seung Won Lee, Sung Hwan Cho, Han Sol Kang, Gwangmook Kim, Jong Sung Kim, Beomjin Jeong, Eui Hyuk Kim, Seunggun Yu, Ihn Hwang, Hyowon Han, Tae Hyun Park, Seok-Heon Jung, Jin-Kyun Lee, Wooyoung Shim, Cheolmin Park
Simultaneous sensing and visualization of pressure provides a useful platform to obtain information about a pressurizing object, but the fabrication of such interactive displays at the single-device level remains challenging. Here, we present a pressure responsive electroluminescent (EL) display that allows for both sensing and visualization of pressure. Our device is based on a two-terminal capacitor with six constituent layers: top electrode/insulator/hole injection layer/emissive layer/electron transport layer/bottom electrode...
April 2, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29575689/tunable-confinement-for-bridging-single-cell-manipulation-and-single-molecule-dna-linearization
#12
Miao Yu, Youmin Hou, Ruyuan Song, Xiaonan Xu, Shuhuai Yao
DNA linearization by nanoconfinement has offered a new avenue toward large-scale genome mapping. The ability to smoothly interface the widely different length scales from cell manipulation to DNA linearization is critical to the development of single-cell genomic mapping or sequencing technologies. Conventional nanochannel technologies for DNA analysis suffer from complex fabrication procedures, DNA stacking at the nanochannel entrance, and inefficient solution exchange. In this work, a dynamic and tunable confinement strategy is developed to manipulate and linearize genomic-length DNA molecules from a single cell...
March 25, 2018: Small
https://www.readbyqxmd.com/read/29540104/stability-of-vincristine-sulfate-doxorubicin-hydrochloride-and-etoposide-phosphate-admixtures-in-polyisoprene-elastomeric-pump-supporting-transition-of-the-epoch-regimen-to-outpatient-care
#13
Darren Svirskis, Sairam Behera, Neera Naidoo, Joanne Beachman, Tarsha Raina, Yongzhi Zhou, Leanne Berkahn, Ian Costello, Yongchuan Gu
Background The EPOCH regimen, consisting of vincristine sulfate, doxorubicin hydrochloride, and etoposide phosphate, is typically administered by continuous infusion over four days to oncology inpatients. If the EPOCH regimen was available to be administered through portable elastomeric pumps, chemotherapy could be transitioned to an outpatient setting, reducing inpatient bed days and overall healthcare costs. However, a lack of stability data for the admixtures in the elastomeric infusion devices currently prevents the transition of the regime to an outpatient setting...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29510497/fabrication-approaches-to-interconnect-based-devices-for-stretchable-electronics-a-review
#14
REVIEW
Steven Nagels, Wim Deferme
Stretchable electronics promise to naturalize the way that we are surrounded by and interact with our devices. Sensors that can stretch and bend furthermore have become increasingly relevant as the technology behind them matures rapidly from lab-based workflows to industrially applicable production principles. Regardless of the specific materials used, creating stretchable conductors involves either the implementation of strain reliefs through insightful geometric patterning, the dispersion of stiff conductive filler in an elastomeric matrix, or the employment of intrinsically stretchable conductive materials...
March 3, 2018: Materials
https://www.readbyqxmd.com/read/29510027/characterization-of-tensioned-pdms-membranes-for-imaging-cytometry-on-microraft-arrays
#15
Matthew DiSalvo, Daniel M Harris, Saurin Kantesaria, Alexis N Peña, Jules D Allbritton-King, Jacqueline H Cole, Nancy L Allbritton
Polydimethylsiloxane (PDMS) membranes can act as sensing elements, barriers, and substrates, yet the low rigidity of the elastomeric membranes can limit their practical use in devices. Microraft arrays rely on a freestanding PDMS membrane as a substrate for cell arrays used in imaging cytometry and cellular isolation. However, the underlying PDMS membrane deforms under the weight of the cell media, making automated analytical microscopy (and thus cytometry and cell isolation) challenging. Here we report the development of microfabrication strategies and physically motivated mathematical modeling of membrane deformation of PDMS microarrays...
April 3, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29502531/assistive-technologies-for-pain-management-in-people-with-amputation-a-literature-review
#16
REVIEW
Kamiar Ghoseiri, Mostafa Allami, Mohammad Reza Soroush, Mohammad Yusuf Rastkhadiv
The prevalence of limb amputation is increasing globally as a devastating experience that can physically and psychologically affect the lifestyle of a person. The residual limb pain and phantom limb pain are common disabling sequelae after amputation surgery. Assistive devices/technologies can be used to relieve pain in people with amputation. The existing assistive devices/technologies for pain management in people with amputation include electrical nerve block devices/technologies, TENS units, elastomeric pumps and catheters, residual limb covers, laser systems, myoelectric prostheses and virtual reality systems, etc...
January 23, 2018: Military Medical Research
https://www.readbyqxmd.com/read/29496321/stability-of-cefazolin-in-polyisoprene-elastomeric-infusion-devices
#17
Rahul P Patel, Jilson Jacob, Mohammed Sedeeq, Long Chiau Ming, Troy Wanandy, Syed Tabish R Zaidi, Gregory M Peterson
PURPOSE: The aim was to investigate the stability of cefazolin in elastomeric infusion devices. METHODS: Elastomeric devices (Infusor LV) that contain cefazolin (3 g/240 mL and 6 g/240 mL) were prepared and stored at 4°C for 72 hours and then at 35°C for 12 hours, followed by 25°C for 12 hours. An aliquot was withdrawn at predefined time points and analyzed for the concentration of cefazolin. Samples were also assessed for changes in pH, solution color, and particle content...
April 2018: Clinical Therapeutics
https://www.readbyqxmd.com/read/29484726/soft-somatosensitive-actuators-via-embedded-3d-printing
#18
Ryan L Truby, Michael Wehner, Abigail K Grosskopf, Daniel M Vogt, Sebastien G M Uzel, Robert J Wood, Jennifer A Lewis
Humans possess manual dexterity, motor skills, and other physical abilities that rely on feedback provided by the somatosensory system. Herein, a method is reported for creating soft somatosensitive actuators (SSAs) via embedded 3D printing, which are innervated with multiple conductive features that simultaneously enable haptic, proprioceptive, and thermoceptive sensing. This novel manufacturing approach enables the seamless integration of multiple ionically conductive and fluidic features within elastomeric matrices to produce SSAs with the desired bioinspired sensing and actuation capabilities...
April 2018: Advanced Materials
https://www.readbyqxmd.com/read/29456464/three-dimensional-multiscale-multistable-and-geometrically-diverse-microstructures-with-tunable-vibrational-dynamics-assembled-by-compressive-buckling
#19
Xin Ning, Heling Wang, Xinge Yu, Julio A N T Soares, Zheng Yan, Kewang Nan, Gabriel Velarde, Yeguang Xue, Rujie Sun, Qiyi Dong, Haiwen Luan, Chan Mi Lee, Aditya Chempakasseril, Mengdi Han, Yiqi Wang, Luming Li, Yonggang Huang, Yihui Zhang, John Rogers
Microelectromechanical systems remain an area of significant interest in fundamental and applied research due to their wide ranging applications. Most device designs, however, are largely two-dimensional and constrained to only a few simple geometries. Achieving tunable resonant frequencies or broad operational bandwidths requires complex components and/or fabrication processes. The work presented here reports unusual classes of three-dimensional (3D) micromechanical systems in the form of vibratory platforms assembled by controlled compressive buckling...
April 11, 2017: Advanced Functional Materials
https://www.readbyqxmd.com/read/29429663/mechanically-robust-dual-responsive-water-dispersible-graphene-based-conductive-elastomeric-hydrogel-for-tunable-pulsatile-drug-release
#20
Sayan Ganguly, Debes Ray, Poushali Das, Priti Prasanna Maity, Subhadip Mondal, V K Aswal, Santanu Dhara, Narayan Ch Das
Nanohybrid hydrogels based on pristine graphene with enhanced toughness and dual responsive drug delivery feature is opening a new era for smart materials. Here pristine graphene hydrogels are synthesized by in situ free radical polymerization where graphene platelets are the nanobuiliding blocks to withstand external stress and shows reversible ductility. Such uniqueness is a mere reflection of rubber-like elasticity on the hydrogels. These nanobuilding blocks serve also the extensive physisorption which enhances the physical crosslinking inside the gel matrix...
April 2018: Ultrasonics Sonochemistry
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