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https://www.readbyqxmd.com/read/28795567/buckled-thin-film-transistors-and-circuits-on-soft-elastomers-for-stretchable-electronics
#1
Giuseppe Cantarella, Christian Vogt, Raoul Hopf, Niko Münzenrieder, Panagiotis Andrianakis, Luisa Petti, Alwin Daus, Stefan Knobelspies, Lars Büthe, Gerhard Troester, Giovanni A Salvatore
Although recent progress in the field of flexible electronics has allowed the realization of biocompatible and conformable electronics, systematic approaches which combine high bendability (< 3 mm bending radius), high stretchability ( > 3-4 %) and low complexity in the fabrication process are still missing. Here, we show a technique to induce randomly-oriented and customized wrinkles on the surface of a biocompatible elastomeric substrate, where Thin-Film Transistors (TFTs) and circuits (inverter and logic NAND gates) based on Amorphous-IGZO are fabricated...
August 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28794001/randomized-comparison-of-ridaforolimus-eluting-and-zotarolimus-eluting-coronary-stents-in-patients-with-coronary-artery-disease-primary-results-from-the-bionics-trial
#2
David E Kandzari, Pieter C Smits, Michael P Love, Ori Ben-Yehuda, Shmuel Banai, Simon D Robinson, Michael Jonas, Ran Kornowski, Rodrigo Bagur, Andres Iniguez, Haim D Danenberg, Robert L Feldman, Rajiv Jauhar, Harish Chandna, Manish A Parikh, Gidon Y Perlman, Mercedes Balcells, Peter M Markham, Melek Ozgu Ozan, Philippe Genereux, Elazer Edelman, Martin B Leon, Gregg W Stone
Background -The safety and efficacy of a novel cobalt alloy-based coronary stent with a durable elastomeric polymer eluting the antiproliferative agent ridaforolimus for treatment of patients with coronary artery disease is undetermined. Methods -A prospective, international 1:1 randomized trial was conducted to evaluate in a noninferiority design the relative safety and efficacy of ridaforolimus-eluting stents (RES) and slow-release zotarolimus-eluting stents (ZES) among 1,919 patients at 76 centers undergoing percutaneous coronary intervention...
August 9, 2017: Circulation
https://www.readbyqxmd.com/read/28763289/improved-hearing-protector-attenuation-through-the-use-of-a-lubricant
#3
Timothy J Ryan, Rebecca S Meier, Ashley Tatarka
A study of 40 novice hearing protection users was conducted to determine if the use of lubricants with hearing protective plugs would enhance their attenuation. Three types of hearing protection devices (i.e., earplugs) were evaluated: roll-down PVC foam, mushroom-style polyurethane foam, and elastomeric flanged. For each earplug type, the right and left ear (dry and lubricated, respectively) personal attenuation rating was determined using a commercially available microphone in real-ear apparatus. Earplug efficacy was observed to increase in the presence of lubricants for all 3 plug types, with average mean elevations by earplug type ranging from 1...
August 1, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28760798/protocol-for-a-randomised-crossover-trial-to-evaluate-patient-and-nurse-satisfaction-with-electronic-and-elastomeric-portable-infusion-pumps-for-the-continuous-administration-of-antibiotic-therapy-in-the-home-the-comparing-home-infusion-devices-chid-study
#4
Jodie G Hobbs, Melissa K Ryan, Brett Ritchie, Janet K Sluggett, Andrew J Sluggett, Lucy Ralton, Karen J Reynolds
INTRODUCTION: Previous studies comparing satisfaction with electronic and elastomeric infusion pumps are limited, and improvements in size and usability of electronic pumps have since occurred. The Comparing Home Infusion Devices (CHID) study plans to assess patient and nurse satisfaction with an elastomeric and electronic pump for delivering intravenous antibiotic treatment in the home. Secondary objectives are to determine pump-related complications and actual antibiotic dose administered, evaluate temperature variation and compare pump operating costs...
July 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28753269/highly-sensitive-flexible-pressure-sensor-based-on-silver-nanowires-embedded-polydimethylsiloxane-electrode-with-microarray-structure
#5
Xingtian Shuai, Pengli Zhu, Wenjin Zeng, Yougen Hu, Xianwen Liang, Yu Zhang, Rong Sun, Ching-Ping Wong
Flexible pressure sensors have attracted increasing research interest because of their potential applications for wearable sensing devices. Herein, a highly sensitive flexible pressure sensor is exhibited based on the elastomeric electrodes and a microarray architecture. Polydimethylsiloxane (PDMS) substrate, coated with silver nanowires (AgNWs), is used as the top electrode, while polyvinylidene fluoride (PVDF) as the dielectric layer. Several transfer processes are applied on seeking facile strategy for the preparation of the bottom electrode via embedding AgNWs into the PDMS film of microarray structure...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28691693/influence-of-physico-mechanical-properties-of-elastomeric-material-for-different-cell-growth
#6
Jyoti Wala, Debashis Maji, Soumen Das
The tunable mechanical and physical properties of Polydimethylsiloxane (PDMS) are commonly utilized for studying cellular dynamics. However, the inherent hydrophobic nature of PDMS limits its application as cell culture films. Various surface modification techniques render PDMS films hydrophilic which alters the surface chemistry, elasticity, roughness and cell attachment of anchorage dependent cell types to the films. The surface properties of thin film lead to alteration in bio-mechano-physical properties of cells and therefore could be used as mechanical signature for viability testing of different normal and cancerous cells...
July 10, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28691142/force-level-of-small-diameter-nickel-titanium-orthodontic-wires-ligated-with-different-methods
#7
Rodrigo Hitoshi Higa, José Fernando Castanha Henriques, Guilherme Janson, Murilo Matias, Karina Maria Salvatore de Freitas, Fernanda Pinelli Henriques, Manoela Fávaro Francisconi
BACKGROUND: The aim of this study was to compare the deflection force in conventional and thermally activated nickel-titanium (NiTi) wires in passive (Damon Q) and active (Bioquick) self-ligating brackets (SLB) and in conventional brackets (CB) tied by two different methods: elastomeric ligature (EL) and metal ligature (ML). METHODS: Two wire diameters (0.014 and 0.016 in.) and 10 specimens per group were used. The specimens were assembled in a clinical simulation device and tested in an Instron Universal Testing Machine, with a load cell of 10 N...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28678968/evaluation-of-deflection-forces-of-orthodontic-wires-with-different-ligation-types
#8
José Fernando Castanha Henriques, Rodrigo Hitoshi Higa, Nayara Thiago Semenara, Guilherme Janson, Thais Maria Freire Fernandes, Renata Sathler
The aim of this study was to evaluate deflection forces of orthodontic wires of different alloys engaged into conventional brackets using several ligation types. Stainless steel, conventional superelastic nickel-titanium and thermally activated nickel-titanium archwires tied into conventional brackets by a ring-shaped elastomeric ligature (RSEL), a 8-shaped elastomeric ligature (8SEL) and a metal ligature (ML) were tested. A clinical simulation device was created especially for this study and forces were measured with an Instron Universal Testing Machine...
July 3, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28647645/adding-dimension-to-cellular-mechanotransduction-advances-in-biomedical-engineering-of-multiaxial-cell-stretch-systems-and-their-application-to-cardiovascular-biomechanics-and-mechano-signaling
#9
REVIEW
O Friedrich, D Schneidereit, Y A Nikolaev, V Nikolova-Krstevski, S Schürmann, A Wirth-Hücking, A L Merten, D Fatkin, B Martinac
Hollow organs (e.g. heart) experience pressure-induced mechanical wall stress sensed by molecular mechano-biosensors, including mechanosensitive ion channels, to translate into intracellular signaling. For direct mechanistic studies, stretch devices to apply defined extensions to cells adhered to elastomeric membranes have stimulated mechanotransduction research. However, most engineered systems only exploit unilateral cellular stretch. In addition, it is often taken for granted that stretch applied by hardware translates 1:1 to the cell membrane...
June 21, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28645997/temperature-profiles-of-antibiotic-containing-elastomeric-infusion-devices-used-by-ambulatory-care-patients
#10
Toni Docherty, Michael Montalto, Joni Leslie, Katrina King, Suzanne Niblett, Tim Garrett
PURPOSE: The temperature profiles of antibiotic-containing elastomeric infusion devices used by ambulatory care patients under various environmental conditions were evaluated. METHODS: A prospective, descriptive survey of temperature exposure was conducted in 4 publically funded hospitals. Over a 12-month period, electronic temperature-recording devices were attached to the antibiotic infusion devices (infusers) of prospectively randomized hospital-in-the-home (HITH) participants...
July 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28634955/human-lung-small-airway-on-a-chip-protocol
#11
Kambez H Benam, Marc Mazur, Youngjae Choe, Thomas C Ferrante, Richard Novak, Donald E Ingber
Organs-on-chips are microfluidic cell culture devices created using microchip manufacturing techniques that contain hollow microchannels lined by living cells, which recreate specialized tissue-tissue interfaces, physical microenvironments, and vascular perfusion necessary to recapitulate organ-level physiology in vitro. Here we describe a protocol for fabrication, culture, and operation of a human lung "small airway-on-a-chip," which contains a differentiated, mucociliary bronchiolar epithelium exposed to air and an underlying microvascular endothelium that experiences fluid flow...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28623642/particle-spallation-in-a-microfluidic-blood-processing-device-the-problem-of-using-peristaltic-pumps-and-silicon-based-microfilters
#12
Monica Faria, Yi Liu, Edward F Leonard
Peristaltic pumps rely on constant compression of elastomeric tubing from which particles may be shed, a phenomenon known as spallation. We studied spallated particles on microfluidic filtration devices with photolithographically prepared micron-level pore fields. Filtration of ultra-pure water through these pores was analyzed using either the usual peristaltic pump or a reciprocating pair of syringe pumps. Using syringe pumps, transmembrane pressure (TMP) values during filtration at 2.5 cm3/min revealed steady filtration for over 80 minutes at 2...
June 15, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28620970/a-coating-free-nonfouling-polymeric-elastomer
#13
Hsiang-Chieh Hung, Priyesh Jain, Peng Zhang, Fang Sun, Andrew Sinclair, Tao Bai, Bowen Li, Kan Wu, Caroline Tsao, Erik J Liu, Harihara S Sundaram, Xiaojie Lin, Payam Farahani, Timothy Fujihara, Shaoyi Jiang
Medical devices face nonspecific biofouling from proteins, cells, and microorganisms, which significantly contributes to complications and device failure. Imparting these devices with nonfouling capabilities remains a major challenge, particularly for those made from elastomeric polymers. Current strategies, including surface coating and copolymerization/physical blending, necessitate compromise among nonfouling properties, durability, and mechanical strength. Here, a new strategy is reported to achieve both high bulk mechanical strength and excellent surface nonfouling properties, which are typically contradictory, in one material...
June 16, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28576717/transient-phase-behavior-of-an-elastomeric-biomaterial-applied-to-abdominal-laparotomy-closure
#14
Omer E Kaymakcalan, Julia L Jin, Zhexun Sun, Nicole G Ricapito, Mary Clare McCorry, Kerry A Morrison, David Putnam, Jason A Spector
Secure closure of the fascial layers after entry into the peritoneal cavity is crucial to prevent incisional hernia, yet appropriate purchase of the tissue can be challenging due to the proximity of the underlying protuberant bowel which may become punctured by the surgical needle or strangulated by the suture itself. Devices currently employed to provide visceral protection during abdominal closure, such as the metal malleable retractor and Glassman Visceral Retainer, are unable to provide complete protection as they must be removed prior to complete closure...
May 31, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28535341/fully-stretchable-optoelectronic-sensors-based-on-colloidal-quantum-dots-for-sensing-photoplethysmographic-signals
#15
Tae-Ho Kim, Chang-Seok Lee, Sangwon Kim, Jaehyun Hur, Sangmin Lee, Keun Wook Shin, Young-Zoon Yoon, Moon Kee Choi, Jiwoong Yang, Dae-Hyeong Kim, Taeghwan Hyeon, Seongjun Park, Sungwoo Hwang
Flexible and stretchable optoelectronic devices can be potentially applied in displays, biosensors, biomedicine, robotics, and energy generation. The use of nanomaterials with superior optical properties such as quantum dots (QDs) is important in the realization of wearable displays and biomedical devices, but specific structural design as well as selection of materials should preferentially accompany this technology to realize stretchable forms of these devices. Here, we report stretchable optoelectronic sensors manufactured using colloidal QDs and integrated with elastomeric substrates, whose optoelectronic properties are stable under various deformations...
June 27, 2017: ACS Nano
https://www.readbyqxmd.com/read/28524191/thermal-scribing-to-prototype-plastic-microfluidic-devices-applied-to-study-the-formation-of-neutrophil-extracellular-traps
#16
Arvind Chandrasekaran, Nikita Kalashnikov, Roni Rayes, Claire Wang, Jonathan Spicer, Christopher Moraes
Innovation in microfluidics-based biological research has been aided by the growing accessibility of versatile microscale fabrication techniques, particularly in rapid prototyping of elastomeric polydimethylsiloxane (PDMS) based devices. However, the use of PDMS presents considerable and often unexpected limitations, particularly in interpreting and validating biological data. To rapidly prototype microfluidic culture systems in conventional plastics commonly used in cell culture, we developed 'thermal scribing', a one-step micromachining technique in which thermoplastics are locally patterned by a heated tip, moving in user-controlled patterns...
May 31, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28523760/bioinspired-composite-microfibers-for-skin-adhesion-and-signal-amplification-of-wearable-sensors
#17
Dirk-M Drotlef, Morteza Amjadi, Muhammad Yunusa, Metin Sitti
A facile approach is proposed for superior conformation and adhesion of wearable sensors to dry and wet skin. Bioinspired skin-adhesive films are composed of elastomeric microfibers decorated with conformal and mushroom-shaped vinylsiloxane tips. Strong skin adhesion is achieved by crosslinking the viscous vinylsiloxane tips directly on the skin surface. Furthermore, composite microfibrillar adhesive films possess a high adhesion strength of 18 kPa due to the excellent shape adaptation of the vinylsiloxane tips to the multiscale roughness of the skin...
May 19, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28512333/hybrid-organic-tandem-solar-cell-comprising-small-molecule-bottom-and-polymer-fullerene-top-subcells-fabricated-by-thin-film-transfer
#18
Yoonseok Ka, Hyejin Hwang, Changsoon Kim
Multilayer structures involving solution-deposited polymer films are difficult to fabricate, not allowing for unrestricted designs of polymer-based optoelectronic devices required for maximizing their performance. Here, we fabricate a hybrid organic tandem solar cell whose top and bottom subcells have polymer:fullerene and small molecules active layers, respectively, by a solvent-free process based on transferring the polymer:fullerene layer from an elastomeric stamp onto a vacuum-deposited bottom subcell. The interface between small-molecule and transferred polymer:fullerene layers is void-free at the nanoscale, allowing for efficient charge transport across the interface...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28485567/stretchable-transparent-and-stretch-unresponsive-capacitive-touch-sensor-array-with-selectively-patterned-silver-nanowires-reduced-graphene-oxide-electrodes
#19
Tae Young Choi, Byeong-Ung Hwang, Bo-Yeong Kim, Tran Quang Trung, Yun Hyoung Nam, Do-Nyun Kim, Kilho Eom, Nae-Eung Lee
Stretchable and transparent touch sensors are essential input devices for future stretchable transparent electronics. Capacitive touch sensors with a simple structure of only two electrodes and one dielectric are an established technology in current rigid electronics. However, the development of stretchable and transparent capacitive touch sensors has been limited due to changes in capacitance resulting from dimensional changes in elastomeric dielectrics and difficulty in obtaining stretchable transparent electrodes that are stable under large strains...
May 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28441503/robust-uniform-and-highly-emissive-quantum-dot-polymer-films-and-patterns-using-thiol-ene-chemistry
#20
Marcus J Smith, Sidney T Malak, Jaehan Jung, Young Jun Yoon, Chun Hao Lin, Sunghan Kim, Kyung Min Lee, Ruilong Ma, Timothy J White, Timothy J Bunning, Zhiqun Lin, Vladimir V Tsukruk
This work demonstrates a facile and versatile method for generating low scattering cross-linked quantum dot (QD)-polymer composite films and patterned highly emissive structures with ultrahigh QD loading, minimal phase separation, and tunable mechanical properties. Uniform QD-polymer films are fabricated using thiol-ene chemistry, in which cross-linked polymer networks are rapidly produced in ambient conditions via fast UV polymerization in bulk to suppress QD aggregation. UV-controlled thiol-ene chemistry limits phase separation through producing highly QD loaded cross-linked composites with loadings above majority of those reported in the literature (<1%) and approaching 30%...
May 15, 2017: ACS Applied Materials & Interfaces
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