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JOURNAL ARTICLE
Mehebub Ali Khan, Anamika Hoque, Md Sanaul Islam, Soumen Ghosh, Md Akhtarul Alam
A biphenyl based coumarin fluorescent molecule, N,N'-bis(7-diethylamino-2-oxo-2 H-chromen-3-yl)methylene)biphenyl-2-2'-dicarbohydrazide (molecule 1) has been synthesized and characterised. Photophysical studies of 1 exhibit solvent polarity dependent absorption and emission maxima. Citrate capped gold nanoparticles (AuNPs) have been mixed with molecule 1 for the preparation of AuNPs/1 conjugate. The association constant of the AuNPs/1 conjugate has been calculated to 4.54 × 104 M- 1 ...
April 22, 2024: Journal of Fluorescence
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JOURNAL ARTICLE
A Arun Prince Milton, Samir Das, Kasanchi M Momin, M C B Prasad, Sabia Khan, G Bhuvana Priya, Sandeep Ghatak, Arnab Sen, K K Baruah
African swine fever (ASF) is a highly fatal and contagious viral disease caused by African swine fever virus (ASFV). It has caused significant economic losses to the swine industry and poses a serious threat to food security worldwide. Diagnostic tests with high sensitivity are essential for the effective management of ASF. Here, we describe a single-tube nested PCR (STN-PCR) assay for the detection of ASFV in which two consecutive amplification steps are carried out within a single tube. Two pairs of primers (outer and inner) were designed to target the p72 gene of ASFV...
April 22, 2024: Archives of Virology
#3
REVIEW
Muhammad Awais, Syed Muhammad Zaigham Abbas Naqvi, Hao Zhang, Linze Li, Wei Zhang, Fuad A Awwad, Emad A A Ismail, M Ijaz Khan, Vijaya Raghavan, Jiandong Hu
Sustainable agricultural practices help to manage and use natural resources efficiently. Due to global climate and geospatial land design, soil texture, soil-water content (SWC), and other parameters vary greatly; thus, real time, robust, and accurate soil analytical measurements are difficult to be developed. Conventional statistical analysis tools take longer to analyze and interpret data, which may have delayed a crucial decision. Therefore, this review paper is presented to develop the researcher's insight toward robust, accurate, and quick soil analysis using artificial intelligence (AI), deep learning (DL), and machine learning (ML) platforms to attain robustness in SWC and soil texture analysis...
December 7, 2023: Bioresources and Bioprocessing
#4
JOURNAL ARTICLE
Ben Li, Hamzah Khan, Farah Shaikh, Abdelrahman Zamzam, Rawand Abdin, Mohammad Qadura
INTRODUCTION: Blood-based biomarkers for abdominal aortic aneurysm (AAA) have been studied individually; however, we considered a panel of proteins to investigate AAA prognosis and its potential to improve predictive accuracy. MATERIALS AND METHODS: Using a prospectively recruited cohort of patients with/without AAA ( n = 452), we conducted a prognostic study to develop a model that accurately predicts AAA outcomes using clinical features and circulating biomarker levels...
April 22, 2024: Journal of Proteome Research
#5
JOURNAL ARTICLE
Pradeep Muralidhar, Vinod Bandela, Abdul Ahad Ghaffar Khan, Shahi Jahan Shah, Abosofyan Salih Atta Elfadeel, Ram B Basany, Devi Singh Amgoth, Shilpa Param
OBJECTIVES: To report and analyze the pattern of maxillofacial injuries in trauma victims and to define the role of a maxillofacial surgeon in an emergency trauma care team. MATERIALS AND METHODS: Trauma patients reported and reporting to the casualty of a tertiaryhospital with facial injuries and other suspected concomitant injuries in the body were included in this study. The complete medical and radiographic records of each patient were reviewed and data was collected in a standard proforma in this 5-year clinical study (3 year of retrospective and 2 year of prospective study)...
April 10, 2024: Acta Odontologica Scandinavica
#6
JOURNAL ARTICLE
Talea Sana, Sumbul Zehra, Majid Khan, Bina Shaheen Siddiqui, Shabana Usman Simjee, Sabira Begum, Taibi B Hadda
The present study was undertaken on the chemical constituents of ethanol extract of aerial parts of Nyctanthes arbor-tristis Linn., and their determination of growth inhibitory activity against glioblastoma multiforme cell line (U87) and urease inhibitory activity. Six constituents were isolated including two new arbortristoside F tetraacetate ( 1 ) and arbortristoside G heptaacetate ( 2 ) and four known arborside A tetraacetate ( 3 ), arborside C pentaacetate ( 4 ), 6,7-di- O -acetyl-6 β -hydroxyloganin hexaacetate ( 5 ) and nyctanthoside heptaacetate ( 6 ) iridoid glycoside acetates...
April 22, 2024: Natural Product Research
#7
JOURNAL ARTICLE
Saad Bin Saeed Ahmed, Shahzaib Naeem, Agha Muhammad Hammad Khan, Bilal Mazhar Qureshi, Amjad Hussain, Bulent Aydogan, Wazir Muhammad
BACKGROUND AND PURPOSE: We proposed an artificial neural network model to predict radiobiological parameters for the head and neck squamous cell carcinoma patients treated with radiation therapy. The model uses the tumor specification, demographics, and radiation dose distribution to predict the tumor control probability and the normal tissue complications probability. These indices are crucial for the assessment and clinical management of cancer patients during treatment planning. METHODS: Two publicly available datasets of 31 and 215 head and neck squamous cell carcinoma patients treated with conformal radiation therapy were selected...
2024: Frontiers in artificial intelligence
#8
Wassim Abouzeid, Noreen Mirza, Paul Bellafiore, Chrystina Kiwan, Amy Paige, Addi Suleiman, Ahsan Khan, Richard Miller
Coronavirus disease 2019 (COVID-19)-induced pericarditis and pericardial myocarditis are common entities; however, the development of pericardial effusion post-COVID-19 infection has only been reported in about 5% of cases. Rapid and acute progression to pericardial tamponade is uncommon, and progression to effusive constrictive pericarditis (ECP) and pericardial decompression syndrome (PDS) is an even rarer phenomenon. We describe these phenomena in this report to raise awareness and aid clinicians in the early diagnosis and management of these conditions...
March 2024: Curēus
#9
Ekrem Yetiskul, Alaukika Agarwal, Salman Khan, Faris Qaqish, Taqi A Rizvi, Hamzah Qandil, Neville Mobarakai
Septic thrombophlebitis of the internal jugular vein is characterized as Lemierre syndrome. Patients typically present with sore throat and fever and may present with a tender neck mass due to thrombophlebitis of the internal jugular vein. We present the case of a 57-year-old male with neck pain, fever, chills, and headaches who was diagnosed with internal jugular vein septic thrombophlebitis associated with catheter-related introduction of bacteria.
March 2024: Curēus
#10
REVIEW
Abshiro H Mayow, Tanya Sinha, Mansoor Ahmad, Ye Kyaw Myint, Samyuktha Balaji, Sandipkumar S Chaudhari, Divine Besong Arrey Agbor, Areeba Khan
This study aims to assess the association between intravenous diltiazem and metoprolol in rate control for atrial fibrillation (AF) patients with rapid ventricular rate, focusing on rate control efficacy and hemodynamic adverse events. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, electronic searches were conducted in Embase, PubMed, and Cochrane Central Register of Controlled Trials (CENTRAL) until February 20, 2024. The primary outcome was achieving ventricular rate control < 110/min...
March 2024: Curēus
#11
JOURNAL ARTICLE
Fahad R Khan, Shakeel Ahmed Memon, Wasim Sajjad
Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a challenging genetic disorder marked by ventricular arrhythmias and sudden cardiac death, particularly in athletes and young adults. Despite its clinical significance, the relative effectiveness and safety of catheter ablation versus conventional management in ARVC are not fully delineated. Objective This study evaluates the efficacy and safety of catheter ablation compared to conventional management in reducing ventricular arrhythmias and improving patient outcomes over five years in ARVC patients...
March 2024: Curēus
#12
REVIEW
Keshav Patel, Jorge A Irizarry-Caro, Adil Khan, Travis Holder, Darrell Salako, Parag Goyal, Min Ji Kwak
Patients with heart failure (HF) have a high prevalence of polypharmacy, which can lead to drug interactions, cognitive impairment, and medication non-compliance. However, the definition of polypharmacy in these patients is still inconsistent. The aim of this scoping review was to find the most common definition of polypharmacy in HF patients. We conducted a scoping review searching Medline, Embase, CINAHL, and Cochrane using terms including polypharmacy, HF and deprescribing, which resulted in 7,949 articles...
April 2024: Cardiology Research
#13
JOURNAL ARTICLE
Omer Farooq, Usman Ghani, Harvey Friedman, Muhammad Sikander Akbar, Hammad Saudye, Sundus Alam, Muhammad Junaid Khan, Sumeet Mutti
BACKGROUND: Atrial septal defects can allow right to left shunting of venous blood which presents clinically as platypnea-orthodeoxia syndrome. It is believed that concomitant presence of aortic root pathologies increases the likelihood of shunting. METHODS: The study included a review of 510 articles listed in PubMed of patients with platypnea-orthodeoxia syndrome. Case reports of patients with extra-cardiac etiologies of platypnea-orthodeoxia were excluded. RESULTS: We reviewed 191 case reports, and 98 cases (51...
April 2024: Cardiology Research
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JOURNAL ARTICLE
Felicia Seemann, Einar Heiberg, Christopher G Bruce, Jaffar M Khan, Amanda Potersnak, Rajiv Ramasawmy, Marcus Carlsson, Håkan Arheden, Robert J Lederman, Adrienne E Campbell-Washburn
AIMS: Pressure-volume (PV) loops have utility in the evaluation of cardiac pathophysiology but require invasive measurements. Recently, a time-varying elastance model to derive PV loops non-invasively was proposed, using left ventricular (LV) volume by cardiovascular magnetic resonance (CMR) and brachial cuff pressure as inputs. Validation was performed using CMR and pressure measurements acquired on the same day, but not simultaneously, and without varying pre-loads. This study validates the non-invasive elastance model used to estimate PV loops at varying pre-loads, compared with simultaneous measurements of invasive pressure and volume from real-time CMR, acquired concurrent to an inferior vena cava (IVC) occlusion...
January 2024: Eur Heart J Imaging Methods Pract
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JOURNAL ARTICLE
Tahreem Arshad, Haji Muhammad Shoaib Khan, Kashif-Ur-Rehman Khan, Abdulaziz S Al-Roujayee, Mohamed Mohany, Maqsood Ahmad, Sana Maryam, Muhammad Bilal Akram, Hasnain Shaukat, Umair Khursheed, Mourad A M Aboul-Soud
The bioactive extracts of traditional medicinal plants are rich in polyphenols and help to rejuvenate skin. The study was designed to assess the skin rejuvenating effects of a stable cream enriched with 4% I. argentea (IaMe) extract. The quantity of polyphenols by spectrophotometric methods was TPC, 101.55 ± 0.03 mg GAE/g and total flavonoid content; 77.14 ± 0.13 mg QE/g, while HPLC-PDA revealed gallic acid; 4.91, chlorogenic acid 48.12, p-coumaric acid 0.43, and rutin 14.23 μg/g...
2024: Frontiers in Pharmacology
#16
JOURNAL ARTICLE
Muhammad Shahzeb Khan, Tayyaba Noor, Erum Pervaiz, Naseem Iqbal, Neelam Zaman
Environmental degradation and energy constraint are important risks to long-term sustainability in the modern world. Water splitting is a vital approach for environmentally friendly and sustainable energy storage, providing a clean way to produce hydrogen without pollutants. Preparing a catalyst that is active, bifunctional, and durable for water splitting is a difficult task. We addressed the difficulty by creating a bifunctional heterogeneous catalyst, MoS2 /rGO, with an ideal weight percentage of 5 wt% by a hydrothermal process...
April 16, 2024: RSC Advances
#17
JOURNAL ARTICLE
Jaimon D Quadros, Sher Afghan Khan, Ma Mohin, Yakub I Mogul, Abdul Aabid, Muneer Baig, Omar Shabbir Ahmed
Molten salts are highly effective as a quenching medium for austempering and martempering processes, enabling precise control of cooling rates to achieve the desired microstructures and mechanical characteristics in steel components. One such promising molten salt is a multicomponent Ca (NO3 )2 -KNO3 molten salt. The current work explores the cooling severity of molten Ca (NO3 )2 -KNO3 mixtures, which are commonly used for such purposes. The said mixture, with varying concentrations and bath temperatures was used for quenching the Inconel probe with thermocouples...
April 16, 2024: ACS Omega
#18
REVIEW
Sonia Morya, Farid Menaa, Catarina Lourenço-Lopes, Cecilia Jimenez-Lopez, Waseem Khalid, Andres Moreno, Ali Ikram, Khalid Ali Khan, Seema Ramniwas, Robert Mugabi
Wine has been utilized as a source for medicinal preparations, combined with various herbs, to treat particular ailments and disorders. By utilizing herb extracts, regular but limited consumption of these herbal wines helps to decrease the need for prescription medications to treat a variety of ailments. The diversity and the composition of the yeast micropopulation significantly contribute to the sensory characteristics of wine. A particular metabolic activity characterizes the growth of each wine yeast species, which determines the concentrations of flavor compounds in the final wine...
April 16, 2024: ACS Omega
#19
Daniel Hui, Scott Dudek, Krzysztof Kiryluk, Theresa L Walunas, Iftikhar J Kullo, Wei-Qi Wei, Hemant K Tiwari, Josh F Peterson, Wendy K Chung, Brittney Davis, Atlas Khan, Leah Kottyan, Nita A Limdi, Qiping Feng, Megan J Puckelwartz, Chunhua Weng, Johanna L Smith, Elizabeth W Karlson, Regeneron Genetics Center, Gail P Jarvik, Marylyn D Ritchie
Apart from ancestry, personal or environmental covariates may contribute to differences in polygenic score (PGS) performance. We analyzed effects of covariate stratification and interaction on body mass index (BMI) PGS (PGS BMI ) across four cohorts of European (N=491,111) and African (N=21,612) ancestry. Stratifying on binary covariates and quintiles for continuous covariates, 18/62 covariates had significant and replicable R 2 differences among strata. Covariates with the largest differences included age, sex, blood lipids, physical activity, and alcohol consumption, with R 2 being nearly double between best and worst performing quintiles for certain covariates...
April 10, 2024: medRxiv
#20
Amy C Moreno, Erin E Watson, Laia Humbert-Vidan, Douglas E Peterson, Lisanne V van Dijk, Teresa Guerrero Urbano, Lisa Van den Bosch, Andrew J Hope, Matthew S Katz, Frank J P Hoebers, Ruth A Aponte Wesson, James E Bates, Paolo Bossi, Adeyinka F Dayo, Mélanie Doré, Eduardo Rodrigues Fregnani, Thomas J Galloway, Daphna Y Gelblum, Issa A Hanna, Christina E Henson, Sudarat Kiat-Amnuay, Anke Korfage, Nancy Y Lee, Carol M Lewis, Charlotte Duch Lynggaard, Antti A Mäkitie, Marco Magalhaes, Yvonne M Mowery, Carles Muñoz-Montplet, Jeffrey N Myers, Ester Orlandi, Jaymit Patel, Jillian M Rigert, Deborah Saunders, Jonathan D Schoenfeld, Ugur Selek, Efsun Somay, Vinita Takiar, Juliette Thariat, Gerda M Verduijn, Alessandro Villa, Nick West, Max J H Witjes, Alex Won, Mark E Wong, Christopher M K L Yao, Simon W Young, Kamal Al-Eryani, Carly E A Barbon, Doke J M Buurman, François J Dieleman, Theresa M Hofstede, Abdul Ahad Khan, Adegbenga O Otun, John C Robinson, Lauren Hum, Jorgen Johansen, Rajesh Lalla, Alexander Lin, Vinod Patel, Richard J Shaw, Mark S Chambers, Daniel Ma, Mabi Singh, Noam Yarom, Abdallah Sherif Radwan Mohamed, Katherine A Hutcheson, Stephen Y Lai, Clifton David Fuller
PURPOSE: Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy (RT) to the head and neck. With over 9 published definitions and at least 16 diagnostic/staging systems, the true incidence and severity of ORNJ are obscured by lack of a standard for disease definition and severity assessment, leading to inaccurate estimation of incidence, reporting ambiguity, and likely under-diagnosis worldwide. This study aimed to achieve consensus on an explicit definition and phenotype of ORNJ and related precursor states through data standardization to facilitate effective diagnosis, monitoring, and multidisciplinary management of ORNJ...
April 9, 2024: medRxiv
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