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https://www.readbyqxmd.com/read/28342600/temporal-changes-in-milk-fatty-acid-distribution-due-to-feeding-different-levels-of-rolled-safflower-seeds-to-lactating-holstein-cows
#1
Amir Ahmadpour, Hassan Aliarabi, Mohammad Ghelich Khan, Robert A Patton, Rupert M Bruckmaier
The objective of this experiment was to follow the time-course changes of the milk fatty acids (FA) and particularly conjugated linoleic acid (CLA), n-3, and n-6 FA in response to feeding whole rolled safflower seed (SS). Eighteen cows were blocked by milk production, days in milk, and parity, and randomly assigned to 1 of 3 diets by replacing whole cottonseed with SS. The control diet contained no SS (SS0), whereas the other diets contained 3% of dry matter as SS (SS3) or 6% SS (SS6). The study was conducted for 8 wk...
March 22, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28339873/evaluation-of-lyme-disease-test-utilization-in-a-low-prevalence-region
#2
Jenna Khan, Patrick Mathias
No abstract text is available yet for this article.
March 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28339368/extrinsic-motives-to-encourage-extracurricular-research-activities-a-reminder-call-to-medical-schools-in-saudi-arabia
#3
Ahmed Abu-Zaid, Leenh O BaHammam, Talal M Hijji, Ismail M Shakir, Abdulaziz M Eshaq, Mohammed Alawadi, Abdulrahman A Al-Khateeb, Tehreem A Khan, Akef Obeidat, Khaled Alkattan
No abstract text is available yet for this article.
March 23, 2017: International Journal of Medical Education
https://www.readbyqxmd.com/read/28339299/the-10th-gcc-closed-forum-rejected-data-gcp-in-bioanalysis-extract-stability-bav-processed-batch-acceptance-matrix-stability-critical-reagents-eln-and-data-integrity-and-counteracting-fraud
#4
Stephanie Cape, Rafiq Islam, Corey Nehls, John Allinson, Afshin Safavi, Patrick Bennett, James Hulse, Chris Beaver, Masood Khan, Shane Karnik, Maria Cruz Caturla, Steve Lowes, Adriana Iordachescu, Luigi Silvestro, Rabab Tayyem, Ron Shoup, Stephanie Mowery, Anahita Keyhani, Andrea Wakefield, Yinghe Li, Jennifer Zimmer, Javier Torres, Philippe Couerbe, Ardeshir Khadang, James Bourdage, Nicola Hughes, Kayode Awaiye, Brent Matthews, Saadya Fatmi, Rhonda Johnson, Christina Satterwhite, Mathilde Yu, Jenny Lin, Laura Cojocaru, Michele Fiscella, Eric Thomas, Kai Kurylak, John Kamerud, Zhongping John Lin, Wei Garofolo, Natasha Savoie, Mike Buonarati, Nadine Boudreau, Clark Williard, Yansheng Liu, Dominic Warrino, Prashant Kale, Neil Adcock, Radha Shekar, Edward O'Connor, Hanna Ritzen, Christina Sanchez, Roger Hayes, Mohammed Bouhajib, Simona Rizea Savu, Bruce Stouffer, Edward Tabler, Jing Tu, Chad Briscoe, Barry van der Strate, Paul Rhyne, Phyllis Conliffe, Ira DuBey, Jim Yamashita, Daniel Tang, Elizabeth Groeber, Jenifer Vija, Michele Malone, Mohamed Osman
The 10th Global CRO Council (GCC) Closed Forum was held in Orlando, FL, USA on 18 April 2016. In attendance were decision makers from international CRO member companies offering bioanalytical services. The objective of this meeting was for GCC members to meet and discuss scientific and regulatory issues specific to bioanalysis. The issues discussed at this closed forum included reporting data from failed method validation runs, GCP for clinical sample bioanalysis, extracted sample stability, biomarker assay validation, processed batch acceptance criteria, electronic laboratory notebooks and data integrity, Health Canada's Notice regarding replicates in matrix stability evaluations, critical reagents and regulatory approaches to counteract fraud...
March 24, 2017: Bioanalysis
https://www.readbyqxmd.com/read/28338994/marfan-syndrome-staging-nonsurgical-vs-surgical-treatments-in-children-with-subluxated-lenses-and-refractive-problems
#5
R V Paul Chan, Arif O Khan, Alex V Levin, Evelyn A Paysse, Patrick A DeRespinis
No abstract text is available yet for this article.
March 1, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28338397/clove-and-its-active-compound-attenuate-free-fatty-acid-mediated-insulin-resistance-in-skeletal-muscle-cells-and-in-mice
#6
Safina Ghaffar, Shabbir Khan Afridi, Meha Fatima Aftab, Munazza Murtaza, Rahman M Hafizur, Sara Sara, Sabira Begum, Rizwana Sanaullah Waraich
Several reports indicate anti-hyperglycemic effects of Syzygium aromaticum. In the present study, we report for the first time that clove extract (SAM) and its compound nigricin (NGC) decreases free fatty acid-mediated insulin resistance in mouse myoblasts. In addition, NGC was able to diminish insulin resistance in a diabetic mouse model. We observed that SAM and its compound NGC exhibited significant antioxidant activity in murine skeletal muscle cells. They also modulated stress signaling by reducing p38 MAP kinase phosphorylation...
March 24, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28338181/gene-expression-of-inflammatory-markers-in-adipose-tissue-between-obese-women-with-polycystic-ovary-and-normal-obese-women
#7
G Alshammari, R Khan, J Brameld, S Amer, M A Lomax
OBJECTIVE: The pathogenesis of polycystic ovary syndrome (PCOS), a common endocrine disease and metabolic disturbance, is still unknown. The aim of the study was to investigate whether patients with PCOS display increased expression of inflammatory markers in adipose tissue. PATIENTS AND METHODS: Two groups of women were investigated, those diagnosed with PCOS (n = 8) and age and BMI-matched normal women (n = 12). Their age was between 20-45 years and all subjects were apparently healthy and did not take any medications...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28338061/heteroleptic-copper-i-complexes-of-scorpionate-bis-pyrazolyl-carboxylate-ligand-with-auxiliary-phosphine-as-potential-anticancer-agents-an-insight-into-cytotoxic-mode
#8
Rais Ahmad Khan, Mohammad Usman, Rajakumar Dhivya, Perumalsamy Balaji, Ali Alsalme, Hamad AlLohedan, Farukh Arjmand, Khalid AlFarhan, Mohammad Abdulkader Akbarsha, Fabio Marchetti, Claudio Pettinari, Sartaj Tabassum
New copper(I) complexes [CuCl(PPh3)(L)] (1: L = LA = 4-carboxyphenyl)bis(3,5-dimethylpyrazolyl)methane; (2: L = LB = 3-carboxyphenyl)bis(3,5-dimethylpyrazolyl)methane) were prepared and characterised by elemental analysis and various spectroscopic techniques such as FT-IR, NMR, UV-Vis, and ESI-MS. The molecular structures of complexes 1 and 2 were analyzed by theoretical B3LYP/DFT method. Furthermore, in vitro DNA binding studies were carried out to check the ability of complexes 1 and 2 to interact with native calf thymus DNA (CT-DNA) using absorption titration, fluorescence quenching and circular dichroism, which is indicative of more avid binding of the complex 1...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28337436/the-lid-domain-in-lipases-structural-and-functional-determinant-of-enzymatic-properties
#9
REVIEW
Faez Iqbal Khan, Dongming Lan, Rabia Durrani, Weiqian Huan, Zexin Zhao, Yonghua Wang
Lipases are important industrial enzymes. Most of the lipases operate at lipid-water interfaces enabled by a mobile lid domain located over the active site. Lid protects the active site and hence responsible for catalytic activity. In pure aqueous media, the lid is predominantly closed, whereas in the presence of a hydrophobic layer, it is partially opened. Hence, the lid controls the enzyme activity. In the present review, we have classified lipases into different groups based on the structure of lid domains...
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/28337150/alteration-in-taste-perception-in-cancer-causes-and-strategies-of-treatment
#10
REVIEW
Babar Murtaza, Aziz Hichami, Amira S Khan, François Ghiringhelli, Naim A Khan
The sense of taste is responsible for the detection and ingestion of food to cover energetic requirements in health and disease. The change in taste perception might lead to malnutrition that is usually one of the frequent causes of morbidity and mortality in patients with cancer. In this review, we summarize the mechanisms of taste perception and how they are altered in cancer. We also address the question of the implication of inflammation, responsible for the alterations in taste modalities. We highlight the role of radio- and chemotherapy in the modulation of taste physiology...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28336529/toe-imaging-of-a-large-aortic-mass-an-unusual-cause-of-systemic-embolization-in-a-septic-patient
#11
Sarah R Blake, Jamal Khan, Adrian Chenzbraun
A 72-year-old woman presented with sepsis and lower limb ischaemia. Transoesophageal echocardiography (TOE) for suspected endocarditis revealed no cardiac pathology or source of emboli but a large thrombus-like mass was noted in a normal size descending aorta (Fig. 1A, Video 1). Repeat TOE after two weeks of anticoagulation showed two new masses and no change in the size of the original one (Fig. 1B). The patient died following bilateral leg amputation. There was no PM to provide pathology confirmation but the most likely diagnosis was of a thrombus, possibly infected...
March 23, 2017: Echo Research and Practice
https://www.readbyqxmd.com/read/28336443/predicting-academic-career-placement-neurosurgery-s-quest-for-the-holy-grail
#12
Nickalus R Khan, Paul Klimo, L Madison Michael
No abstract text is available yet for this article.
March 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28336339/optimal-feature-selection-from-fnirs-signals-using-genetic-algorithms-for-bci
#13
Farzan Majeed Noori, Noman Naseer, Nauman Khalid Qureshi, Hammad Nazeer, Rayyan Azam Khan
In this paper, a novel technique for determination of the optimal feature combinations and, thereby, acquisition of the maximum classification performance for a functional near-infrared spectroscopy (fNIRS)-based brain-computer interface (BCI), is proposed. After obtaining motor-imagery and rest signals from the motor cortex, filtering is applied to remove the physiological noises. Six features (signal slope, signal mean, signal variance, signal peak, signal kurtosis and signal skewness) are then extracted from the oxygenated hemoglobin (HbO)...
March 20, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28336246/does-hip-arthroscopy-have-a-role-in-the-treatment-of-developmental-hip-dysplasia
#14
Jacob M Kirsch, Moin Khan, Asheesh Bedi
BACKGROUND: Indications for hip arthroscopy in mildly dysplastic patients with a symptomatic hip remain controversial. METHODS: This article provides a concise review of the available literature evaluating the role of hip arthroscopy in treating symptomatic dysplasia. Potential indications for hip arthroscopy in isolation are reviewed. Emerging evidence on the role of hip arthroscopy based on patient-specific pathomorphology is highlighted. RESULTS: Hip arthroscopy in isolation may be helpful for select dysplastic patients with dynamic impingement or microinstability...
February 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28335359/temperature-and-angle-dependent-magnetic-properties-of-ni-nanotube-arrays-fabricated-by-electrodeposition-in-polycarbonate-templates
#15
Yonghui Chen, Chen Xu, Yibo Zhou, Khan Maaz, Huijun Yao, Dan Mo, Shuangbao Lyu, Jinglai Duan, Jie Liu
Parallel arrays of Ni nanotubes with an external diameter of 150 nm, a wall thickness of 15 nm, and a length of 1.2 ± 0.3 µm were successfully fabricated in ion-track etched polycarbonate (PC) templates by electrochemical deposition. The morphology and crystal structure of the nanotubes were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray diffraction (XRD). Structural analyses indicate that Ni nanotubes have a polycrystalline structure with no preferred orientation...
December 1, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335203/temperature-dependent-magnetic-response-of-antiferromagnetic-doping-in-cobalt-ferrite-nanostructures
#16
Adeela Nairan, Maaz Khan, Usman Khan, Munawar Iqbal, Saira Riaz, Shahzad Naseem
In this work MnxCo1-xFe₂O₄ nanoparticles (NPs) were synthesized using a chemical co-precipitation method. Phase purity and structural analyses of synthesized NPs were performed by X-ray diffractometer (XRD). Transmission electron microscopy (TEM) reveals the presence of highly crystalline and narrowly-dispersed NPs with average diameter of 14 nm. The Fourier transform infrared (FTIR) spectrum was measured in the range of 400-4000 cm(-1) which confirmed the formation of vibrational frequency bands associated with the entire spinel structure...
April 18, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335200/structural-and-magnetic-response-in-bimetallic-core-shell-magnetic-nanoparticles
#17
Adeela Nairan, Usman Khan, Munawar Iqbal, Maaz Khan, Khalid Javed, Saira Riaz, Shahzad Naseem, Xiufeng Han
Bimagnetic monodisperse CoFe₂O₄/Fe₃O₄ core/shell nanoparticles have been prepared by solution evaporation route. To demonstrate preferential coating of iron oxide onto the surface of ferrite nanoparticles X-ray diffraction (XRD), High resolution transmission electron microscope (HR-TEM) and Raman spectroscopy have been performed. XRD analysis using Rietveld refinement technique confirms single phase nanoparticles with average seed size of about 18 nm and thickness of shell is 3 nm, which corroborates with transmission electron microscopy (TEM) analysis...
April 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334655/morpholine-or-methylpiperazine-and-salicylaldimine-based-heteroleptic-square-planner-platinum-ii-complexes-in%C3%A2-vitro-anticancer-study-and-growth-retardation-effect-on-e-%C3%A2-coli
#18
Faiz-Ur Rahman, Amjad Ali, Inam Ullah Khan, Hong-Quan Duong, Shang-Bo Yu, Yue-Jian Lin, Hui Wang, Zhan-Ting Li, Dan-Wei Zhang
Morpholine and methylpiperazine are among the most important structural parts of different drugs including organic chemotherapeutic agents. In the current study we incorporated these entities as co-ligand and a series of structurally related mono- and di-metallic square planner Pt(II) complexes (Pt(II)(salicylaldimine)(morpholine)Cl C1a-C3a, Pt(II)(salicylaldimine) (methylpiperazine)Cl C1b-C3b, di-metallic Pt(II)2(bis-salicylaldimine)(morpholine)2Cl2C4a and Pt(II)2(bis-salicylaldimine)(methylpiperazine)2Cl2C4b were prepared...
March 18, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28334290/field-evolved-resistance-of-bemisia-tabaci-hemiptera-aleyrodidae-to-carbodiimide-and-neonicotinoids-in-pakistan
#19
Mushtaq Ahmad, Rashid A Khan
The evolution of resistance to carbodiimide (a toxic metabolite of diafenthiuron) and four neonicotinoids imidacloprid, acetamiprid, thiamethoxam, and thiacloprid in the Pakistani populations of sweetpotato whitefly (Bemisia tabaci Gennadius) was monitored from 1996 to 2015 using a leaf-dip bioassay. Diafenthiuron, imidacloprid, and acetamiprid were introduced into Pakistani agriculture in mid-1990s and heavily used since then, because B. tabaci resistance and consequently control failures to conventional insecticides such as organophosphates, carbamates, and pyrethroids were widespread during the 1990s...
March 3, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28332912/twelve-tips-for-the-production-of-digital-chalk-talk-videos
#20
Jasmine Rana, Henrike Besche, Barbara Cockrill
Increasingly over the past decade, faculty in medical and graduate schools have received requests from digital millennial learners for concise faculty-made educational videos. At our institution, over the past couple of years alone, several hundred educational videos have been created by faculty who teach in a flipped-classroom setting of the pre-clinical medical school curriculum. Despite the appeal and potential learning benefits of digital chalk-talk videos first popularized by Khan Academy, we have observed that the conceptual and technological barriers for creating chalk-talk videos can be high for faculty...
March 23, 2017: Medical Teacher
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