keyword
MENU ▼
Read by QxMD icon Read
search

Sinonasal adenocarcinoma

keyword
https://www.readbyqxmd.com/read/28321774/intestinal-type-adenocarcinoma-classification-immunophenotype-molecular-features-and-differential-diagnosis
#1
Ilmo Leivo
Intestinal-type adenocarcinoma is the second most frequent sinonasal adenocarcinoma. High incidence of these tumors is seen among workers with occupational wood dust exposure, particularly of hardwood dusts. Intestinal-type adenocarcinoma has striking histomorphologic and immunophenotypic similarities with colorectal adenocarcinomas, but on the level of molecular pathologic mechanisms these tumors have their own specific features different from gastrointestinal tumors. This article provides an update on current histopathologic classification of intestinal-type adenocarcinomas, their immunophenotypic properties, recent advances in molecular pathologic features and differential diagnostic considerations...
March 20, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28270733/nasopharyngeal-non-intestinal-type-adenocarcinoma-a-case-report-and-updated-review-of-the-literature
#2
C Jain, L Caulley, K I Macdonald, B Purgina, C K Lai, B Esche, S Johnson-Obaseki
BACKGROUND: Non-intestinal-type adenocarcinoma is a malignancy traditionally found in the sinonasal cavity. To our knowledge, this case is the first reported of this rare condition originating in the nasopharynx. CASE PRESENTATION: A 67-year-old woman with nasopharyngeal non-intestinal-type adenocarcinoma, with an accompanying parapharyngeal mass received primary radiation treatment for both lesions. Her tumour subsequently persisted, with a concomitant conversion in pathology from a low- to a high-grade malignancy...
February 2017: Current Oncology
https://www.readbyqxmd.com/read/28247233/update-from-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumours-tumors-of-the-nasal-cavity-paranasal-sinuses-and-skull-base
#3
Edward B Stelow, Justin A Bishop
The sinonasal tract remains an epicenter of a diverse array of neoplasia. This paper discusses changes to the WHO classification system of tumors involving this area. In particular, seromucinous hamartoma, NUT carcinoma, biphenotypic sinonasal sarcoma, HPV-related carcinoma with adenoid cystic features, SMARCB1-deficient carcinoma, and renal cell-like adenocarcinoma are discussed.
March 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28216876/wheatgrass-extract-ameliorates-hypoxia-induced-mucin-gene-expression-in-a549-cells
#4
Ju Hwan Sim, Moon-Hee Choi, Hyun-Jae Shin, Ji-Eun Lee
BACKGROUND: Wheatgrass is known to have antioxidant, antiaging, and anti-inflammatory effect. However, its protective effect against hypoxia is not yet evaluated. OBJECTIVE: In this study, we evaluated the protective and anti-inflammatory effect of wheatgrass against the hypoxia in airway epithelial cells. MATERIALS AND METHODS: A549 human lung adenocarcinoma cells were incubated in a hypoxic condition (CO2 5%/O2 1%) for 24 hr in the presence of different concentration of wheatgrass 50, 75, 100, and 150 μg/mL, and the magnitude of each immunologic response produced by the A549 cells was compared...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28173955/nasopharyngeal-adenocarcinoma-a-population-based-analysis
#5
Edward C Kuan, Jose E Alonso, Armin Arshi, Maie A St John
OBJECTIVES/HYPOTHESIS: To describe the incidence and determinants of survival of patients with nasopharyngeal adenocarcinoma between the years of 1973 to 2012 using the Surveillance, Epidemiology, and End Result (SEER) database. STUDY DESIGN: Retrospective cohort study using a national database. METHODS: The SEER registry was utilized to calculate survival trends for patients with nasopharyngeal adenocarcinoma between 1973 and 2012. Patient data was then analyzed with respect to histopathology, age, sex, race, stage, grade, and treatment modalities (surgery and radiation therapy)...
January 31, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28153137/glandular-neoplasia-of-the-sinonasal-tract
#6
REVIEW
Edward B Stelow
Glandular lesions that cannot be diagnosed readily as salivary gland tumors occur uncommonly in the upper aerodigestive tract. They occur only with some frequency within the sinonasal tract. Well-characterized lesions at this site include the respiratory epithelial adenomatoid hamartoma, seromucinous hamartoma, and intestinal and non-intestinal-type adenocarcinomas. This article reviews the clinicopathologic features of these fascinating lesions.
March 2017: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/28050382/intestinal-type-adenocarcinoma-from-inverted-papilloma-a-rare-recurrence
#7
Garima Singh, Meeta Singh, Mansi Chandana, Sompal Singh, Namrata Nargotra
Inverted Papilloma (IP) is an uncommon and locally aggressive benign tumour of sinonasal region, which tends to recur after surgical resection. Most tumours are confined to the lateral nasal wall and sinuses, with maxillary sinus being most commonly affected and a male preponderance. It has a known association with in situ and invasive carcinomas with a <10% rate of malignant transformation. Most common association has been seen with squamous cell carcinoma and extremely rare association with adenocarcinoma and small cell carcinoma...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28032937/prognostic-value-of-pretreatment-peripheral-blood-markers-in-paranasal-sinus-cancer-neutrophil-to-lymphocyte-and-platelet-to-lymphocyte-ratio
#8
Mario Turri-Zanoni, Giovanni Salzano, Alessia Lambertoni, Marta Giovannardi, Apostolos Karligkiotis, Paolo Battaglia, Paolo Castelnuovo
BACKGROUND: Pretreatment hematological markers have emerged as prognostic factors for several cancers. The purpose of this study was to present our investigation of the value of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting recurrence and mortality for patients with primary sinonasal cancers (SNCs). METHODS: We carried out a retrospective review of patients with SNC who had been treated using endoscopic approaches from 2002 to 2014 at a single institute...
December 29, 2016: Head & Neck
https://www.readbyqxmd.com/read/28032289/sinonasal-renal-cell-like-carcinoma-case-report-and-review-of-the-literature
#9
Mark Kubik, Nicholas Barasch, Garret Choby, Raja Seethala, Carl Snyderman
The differential diagnosis for clear cell neoplasms of the sinonasal tract is wide but critical to understand. In this paper, we describe a case of renal cell-like adenocarcinoma (SNRCLA) presenting as a paranasal sinus mass with clear cell morphology. The relevant literature is reviewed and the workup for clear cell neoplasms described. SNRCLA is a rarely encountered low grade glandular malignancy of the paranasal sinuses. Despite its morphologic mimicry of renal cell carcinoma, SNRCLA demonstrates a seromucinous phenotype and is associated with a favorable prognosis and low recurrence rates after surgical resection...
December 28, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/28011123/sinonasal-adenocarcinoma-clinical-outcomes-and-predictive-factors
#10
J Michel, T Radulesco, M Penicaud, J Mancini, P Dessi
A retrospective study of 39 patients treated for sinonasal adenocarcinoma between 1995 and 2010 was performed. Epidemiological, clinical, histological, and therapeutic aspects of this series of patients were analyzed statistically and their impact in terms of overall and disease-free survival established using the Kaplan-Meier method. A search for prognostic factors was made using a log-rank test. The male to female sex ratio was 6.8 to 1. The average age at diagnosis was 65.7 years (range 40.2-85.6 years)...
December 20, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27916624/primary-paranasal-sinus-clear-cell-carcinoma-with-ewsr1-atf1-fusion-report-of-two-molecularly-confirmed-cases-exhibiting-unique-histopathology
#11
Jui Lan, Shun-Chen Huang, Yi-Hsien Chen, Wei-Chih Chen, Ying-Tai Jin, Ying-Chou Lu, Chih-Yen Chien, Hsuan-Ying Huang
Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade tumor of the salivary glands made up of clear cells that form cords and nests in hyalinized stroma. To date, primary HCCCs of the paranasal sinus have not been described. This article presents two cases of HCCC of the maxillary sinus with unusual glandular formation and lymphoplasmacytic stroma in Case 1 and a characteristic solid nest pattern and fibrocellular and hyalinized stroma in Case 2. Immunohistochemical studies excluded myoepithelial origin and sinonasal renal cell-like adenocarcinomas...
December 1, 2016: Human Pathology
https://www.readbyqxmd.com/read/27859278/outcomes-of-nonsurgical-management-of-locally-advanced-carcinomas-of-the-sinonasal-cavity
#12
Shamit Chopra, Dev P Kamdar, David S Cohen, Lance K Heilbrun, Daryn Smith, Harold Kim, Ho-Sheng Lin, John R Jacobs, George Yoo
OBJECTIVE: To determine the outcome of definitive concurrent chemoradiation with platinum for locally advanced sinonasal carcinomas. STUDY DESIGN: Retrospective cohort. METHODS: Twenty-three nonsurgically and definitively treated patients diagnosed between July 1998 and February 2009 were analyzed. Patients with adenoid cystic carcinoma or adenocarcinoma were treated with photons and neutrons; the other histologies received photons alone. The vast majority received chemotherapy...
April 2017: Laryngoscope
https://www.readbyqxmd.com/read/27830670/sinonasal-adenocarcinoma-in-a-patient-without-exposure-to-risk-factors-case-report-and-review-of-the-literature
#13
Luciano Izzo, Sara Izzo, Pierfrancesco Di Cello, Vollono Laura, Violante Orazia, Gradini Roberto, Paolo Izzo
OBJECTIVE: Sinonasal adenocarcinoma is a tumor typically associated with exposure to occupational carcinogens. The International Agency for Research on Cancer (IARC) published several data in order to classify carcinogenic power of physical-chemical agents as far as sinonasal cancer is concerned. MATERIALS AND METHODS: We report a clinical case of sinonasal adenocarcinoma observed in an 84 years old patient, without clinical history of past exposure to carcinogens, smoke and alcohol...
July 29, 2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27681565/non-intestinal-type-sinonasal-cancers-and-exposure-to-occupational-carcinogens-a-case-control-study
#14
Matteo Bonzini, Nadia Facchinetti, Laura Zanetta, Davide Parassoni, Rossana Borchini, Paolo Battaglia, Mario Turri-Zanoni, Paolo Castelnuovo, Marco Mario Ferrario
BACKGROUND: Sinonasal cancers are rare, often fatal, tumors with a very high proportion of cases attributable to occupational exposures. The relevance of different carcinogens deeply varies among histological subtypes, with intestinal type adenocarcinomas (ITAC) characterized by a very large proportion of workers exposed to wood dust. The role of occupation in the etiology of other histotypes is less clear and more disputed, with authors questioning the possible occupational origin of non-ITAC cancers...
2016: La Medicina del Lavoro
https://www.readbyqxmd.com/read/27576899/relationship-between-18-fdg-pet-and-different-types-of-sinonasal-malignancies
#15
Marylisa Felix-Ravelo, Ayoub Bey, Fabien Arous, Solène Paris-Grandpierre, Roger Jankowski, Duc Trung Nguyen
CONCLUSION: The sensitivity and specificity of a (18)FDG-PET scan may be different according to the histology. The SUVmax and SUV ratio may reflect the tumor's aggressive behavior. OBJECTIVES: To describe the characteristics of PET/CT scans, including the maximum standard uptake values (SUVmax), at initial diagnosis according to six main types of sinonasal malignancies: sinonasal adenocarcinoma (SNAC), sinonasal undifferentiated carcinoma (SNUC), adenoid cystic carcinoma (ACC), sinonasal malignant melanoma (SMM), olfactory neuroblastoma (ONB), and sinonasal neuroendocrine carcinoma (SNEC)...
February 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27453718/a-case-case-study-on-sinonasal-cancer-prevention-effect-from-dust-reduction-in-woodworking-and-risk-of-mastic-solvents-in-shoemaking
#16
Enzo Emanuelli, Enrico Alexandre, Diego Cazzador, Vera Comiati, Tiziana Volo, Alessia Zanon, Maria Luisa Scapellato, Mariella Carrieri, Alessandro Martini, Giuseppe Mastrangelo
BACKGROUND AND AIMS: Sinonasal cancers (SNCs) are rare neoplasms, accounting for about 3 % of head and neck cancers, with squamous cell carcinoma (SCC) and adenocarcinoma (ADC) as the most common subtypes. ADCs present strong associations with occupational wood dust exposure. Preventive measures have progressively reduced wood dust concentrations in workplaces but no study has evaluated the effectiveness of such interventions. Few studies indicate associations between ADC and exposure to solvents, which is common in the shoe industry, but this hypothesis still needs confirmation...
2016: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/27402540/invasive-sinonasal-adenocarcinoma-with-an-absent-olfactory-bulb-a-case-report
#17
Thomas H Newman, Geoffrey A Tipper, Zakier Hussain
Sinonasal adenocarcinomas are rare, locally invasive tumours. In this case the symptomatic profile was unusual and the diagnosis was missed at the primary care stage. Interestingly this would be the first documented case with an absent ipsilateral olfactory bulb. A 55-year old male presented with symptoms of behavioural change and mild headaches. He was later found to have a large Sinonasal adenocarcinoma which penetrated the skull base. This was treated by a combined craniotomy and endonasal approach. Sinonasal adenocarcinomas are unusual tumours and further research is required in order to clarify management strategies and prognosis...
2016: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/27363404/comparison-of-endoscopic-and-external-resections-for-sinonasal-instestinal-type-adenocarcinoma
#18
Geoffrey Mortuaire, Xavier Leroy, Claire Vandenhende-Szymanski, Dominique Chevalier, Anne-Sophie Thisse
Endoscopic sinus surgery (ESS) is considered as a valid option in the management of nasal adenocarcinoma (ADC). Comparative studies with open approaches are still required. A monocentric retrospective study was carried out from May 2002 to December 2013, including 43 patients with intestinal-type adenocarcinoma of the ethmoid sinus. Non-resectable tumours or recurrences were excluded. Before 2008, open approach with lateral rhinotomy (LR) was performed as the gold standard of treatment. From 2008, ESS was systematically used as a first-line option as long as a complete resection was achievable...
December 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27301901/gene-methylation-profiling-in-sinonasal-adenocarcinoma-and-squamous-cell-carcinoma
#19
Maria Costales, Alejandro López-Hernández, Cristina García-Inclán, Blanca Vivanco, Fernando López, José Luis Llorente, Mario A Hermsen
OBJECTIVE: To identify epigenetic events in intestinal-type sinonasal adenocarcinoma (ITAC) and sinonasal squamous cell carcinoma (SNSCC) and to evaluate their relation to clinicopathologic features and follow-up data. STUDY DESIGN: Retrospective study. SETTING: Academic research hospital. SUBJECTS AND METHODS: The methylation status of 23 genes in 50 ITACs and 32 SNSCCs was analyzed by methylation-specific multiplex ligation-dependent probe amplification and its relation to clinicopathologic features and follow-up data...
June 14, 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/27258560/the-role-of-satb2-as-a-diagnostic-marker-of-sinonasal-intestinal-type-adenocarcinoma
#20
Alena Skalova, Aylin Sar, Jan Laco, Alena Metelkova, Marketa Miesbauerova, Petr Steiner, Marian Švajdler, Michal Michal
BACKGROUND: Intestinal-type adenocarcinoma (ITAC) of the nasal cavity and paranasal sinuses is an uncommon tumor associated with exposure to wood and leather dust, nickel, and possibly smoking. ITAC shares phenotypical features with colorectal carcinoma. In contrast to most non-intestinal-type sinonasal adenocarcinomas, ITAC is an aggressive adenocarcinoma with poor clinical outcome; therefore, its reliable separation from non-ITAC is very important. AIM: The use of a combination of immunohistochemical markers of intestinal differentiation was tested in a cohort of sinonasal carcinomas of different types...
June 2, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
keyword
keyword
118765
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"