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Thomas A Swain, Gerald McGwin
BACKGROUND: Yoga has become more popular among people in the United States and has been touted by both yoga participants as well as some physicians and researchers for its health benefits. While the health benefits have been studied, the frequency of injury among yoga participants has not been well documented. PURPOSE: Injury incidence, rates, and types associated with yoga in the United States have not been quantified. This study estimates US yoga-associated injury incidence and characterizes injury type over a 13-year period...
November 2016: Orthopaedic Journal of Sports Medicine
Gonzalo Abellán, Vicent Lloret, Udo Mundloch, Mario Marcia, Christian Neiss, Andreas Görling, Maria Varela, Frank Hauke, Andreas Hirsch
Black phosphorus (BP) was functionalized with organic moieties on the basis of liquid exfoliation. The treatment of BP with electron-withdrawing 7,7,8,8-tetracyano-p-quinodimethane (TCNQ) led to electron transfer from BP to the organic dopant. On the other hand, the noncovalent interaction of BP with a perylene diimide was mainly due to van der Waals interactions but also led to considerable stabilization of the BP flakes against oxygen degradation.
November 14, 2016: Angewandte Chemie
Daniel R Grant, Scott J Schoenleber, Alicia M McCarthy, Geraldine I Neiss, Petya K Yorgova, Kenneth J Rogers, Peter G Gabos, Suken A Shah
BACKGROUND: Physicians play a role in the current prescription drug-abuse epidemic. Surgeons often prescribe more postoperative narcotic pain medication than patients routinely need. Although narcotics are effective for severe, acute, postoperative pain, few evidence-based guidelines exist regarding the routinely required amount and duration of use post-hospital discharge. METHODS: Patients in a prospective cohort undergoing posterior spinal fusion for idiopathic scoliosis were asked preoperatively to rate their pain level, the level of pain expected each week postoperatively, and their pain tolerance...
September 21, 2016: Journal of Bone and Joint Surgery. American Volume
M Hackl, S Lappen, W F Neiss, M Scaal, L P Müller, K Wegmann
BACKGROUND: Olecranon osteotomy is an established approach for the treatment of distal humerus fractures. It should be performed through the bare area of the proximal ulna to avoid iatrogenic cartilage lesions. OBJECTIVES: The goal of this study was to analyze the anatomy of the proximal ulna with regard to the bare area and, thereby, to optimize the hitting area of the bare area when performing olecranon osteotomy. MATERIALS AND METHODS: The bare areas of 30 embalmed forearm specimens were marked with a radiopaque wire and visualized three-dimensionally with a mobile C‑arm...
October 2016: Der Orthopäde
Thomas A Swain, Albert Scott Tully, Travis Redford, Gerald McGwin
BACKGROUND: Hair removal practices have changed in frequency and location on the body. Previous research on hair removal injuries has focused on a specific body region, age, or gender. OBJECTIVE: This study sought to take a broader perspective of hair removal-associated injuries in the United States which sought treatment at emergency departments. METHODS: Data from the National Electronic Injury Surveillance System (NEISS) from 1991 to 2014 were used to identify hair removal-related injuries...
September 5, 2016: Journal of Cosmetic Dermatology
M Hackl, T Leschinger, C Ries, W F Neiss, L P Müller, K Wegmann
BACKGROUND: Chronic posterolateral rotatory instability (PLRI) of the elbow is the result of an insufficiency of the lateral collateral ligament (LCL). Lateral ulnar collateral ligament (LUCL) reconstruction represents a well-established treatment method for PLRI. However, recurrent instability remains a problem. OBJECTIVES: The goal of this in-vitro study was to evaluate the posterolateral rotatory stability of the intact elbow, after sectioning of the LCL and after LUCL reconstruction with a triceps tendon autograft and double BicepsButton(TM) fixation...
October 2016: Der Orthopäde
Brandon Miller, Eden Yelverton, Jesus Monico, William Replogle, J Randall Jordan
INTRODUCTION: Golf carts are increasingly used off the golf course and are often viewed as innocuous modes of transportation. However, research has shown they can cause significant injuries, particularly to children. OBJECTIVES: Analyze golf cart related head and neck injuries in children and adults from a national database. METHODS: The National Electronic Injury Surveillance System (NEISS) was queried for golf cart injuries. The NEISS tracks consumer product related injuries from a sampling of approximately 100 emergency departments across the United States...
September 2016: International Journal of Pediatric Otorhinolaryngology
P Viala, J Gendre, M Colas, M Neiss, N Brunetti, E Karoubi, S Laudier, V Prat, C Sengelin, P Baune
No abstract text is available yet for this article.
June 2016: Médecine et Maladies Infectieuses
Steven F DeFroda, Joseph A Gil, Brett D Owens
PURPOSE: To quantify and compare the incidence of lower extremity injuries in skiers and snowboarders who present to emergency rooms in the United States. METHODS: Cross-sectional study of lower extremity injuries in skiers and snowboarders that were evaluated in emergency rooms in the United States. The National Electric Injury Surveillance System (NEISS) database was queried from January 1st, 2014 and December 31st, 2014 and the reported cases of lower extremity injuries in skiers and snowboarders were examined...
July 7, 2016: Injury
Curtis Hanba, Peter F Svider, Frank S Chen, Michael A Carron, Adam J Folbe, Jean Anderson Eloy, Giancarlo F Zuliani
Importance: There are well-described racial, sex, and age differences related to osteoporosis and hip and/or extremity fractures. Nonetheless, there has been virtually no inquiry evaluating whether these findings carry over to facial fracture. Objective: To characterize the incidence of facial fractures by patient demographics and injury mechanism, focusing on whether differences are noted with race, sex, and advancing age. Main Outcomes and Measures: Retrospective analysis of the National Electronic Injury Surveillance System (NEISS) was performed in October and November 2015, specifically evaluating adult emergency department (ED) visits from 2012 to 2014 related to facial trauma...
December 1, 2016: JAMA Facial Plastic Surgery
Andrew R Conery, Richard C Centore, Adrianne Neiss, Patricia J Keller, Shivangi Joshi, Kerry L Spillane, Peter Sandy, Charlie Hatton, Eneida Pardo, Laura Zawadzke, Archana Bommi-Reddy, Karen E Gascoigne, Barbara M Bryant, Jennifer A Mertz, Robert J Sims
No abstract text is available yet for this article.
2016: ELife
Theresa R Tonozzi, Suzanne M Marsh, Audrey A Reichard, Ruchi Bhandari
BACKGROUND: Research suggests Hispanic workers underreport injuries/illnesses to their employer. METHODS: The National Electronic Injury Surveillance System-occupational supplement was used to conduct a follow-back study of workers treated in emergency departments (EDs) from June 2012 through December 2013. RESULTS: An estimated 448,000 (95%CI 230,000-665,000) Hispanic workers treated in EDs for a work-related injury or illness were represented by 362 completed interviews...
August 2016: American Journal of Industrial Medicine
Suzanne M Marsh, Audrey A Reichard, Ruchi Bhandari, Theresa R Tonozzi
OBJECTIVE: Researchers from the National Institute for Occupational Safety and Health (NIOSH) share detailed methodologies from conducting two follow-back studies initiated in 2010 that were designed to assess whether workers reported their injuries and illnesses to their employers and to identify worker incentives and disincentives for reporting work-related injuries to employers. METHODOLOGY: Study respondents were sampled from the National Electronic Injury Surveillance System occupational supplement (NEISS-Work), an emergency department-based surveillance system...
August 2016: American Journal of Industrial Medicine
Ulisses Gaspar Neiss, Neusa Hamada
The larva of Palaemnema brasiliensis Machado, 2009 is described and illustrated based on last-instar larvae and exuviae of reared larvae collected in a blackwater stream in Barcelos and Presidente Figueiredo municipalities, Amazonas state, Brazil. The larva of P. brasiliensis can be distinguished from the two South American species of the genus with described larvae (P. clementia Selys and P. mutans Calvert), mainly by presence of a single obtuse cusp on the labial palp, the presence and configuration of setae in the caudal lamellae, and the proportional length of terminal filaments of the caudal lamellae...
2016: Zootaxa
Peter F Svider, Michael Bobian, Houmehr Hojjat, Anthony Sheyn, Giancarlo Zuliani, Jean Anderson Eloy, Adam J Folbe
BACKGROUND: Winter activities offer children and adolescents an outdoor recreational opportunity during the coldest months. Our objectives were to estimate the national incidence of facial injury associated with recreational winter activities. Furthermore, we analyze demographic trends and clinical characteristics of patients presenting to emergency departments (EDs). METHODS: The National Electronic Injury Surveillance System (NEISS), a population-based resource, was evaluated for ED visits from 2010 to 2014 for children injured from "active" winter -undertakings (snowboarding, skiing, ice skating) and sledding/tubing...
August 2016: International Journal of Pediatric Otorhinolaryngology
S Gupta, A Weston, J Bearrs, T Thode, A Neiss, R Soldi, S Sharma
BACKGROUND: Lysine-specific demethylase 1 (LSD1 or KDM1A) overexpression correlates with poor survival and castration resistance in prostate cancer. LSD1 is a coregulator of ligand-independent androgen receptor signaling promoting c-MYC expression. We examined the antitumor efficacy of LSD1 inhibition with HCI-2509 in advanced stages of prostate cancer. METHODS: Cell survival, colony formation, histone methylation, c-MYC level, c-MYC expression, cell cycle changes and in vivo efficacy were studied in castration-resistant prostate cancer cells upon treatment with HCI-2509...
June 28, 2016: Prostate Cancer and Prostatic Diseases
Thomas A Swain, Gerald McGwin, Russell Griffin
OBJECTIVE: Previous studies have reported that children are at risk of severe injuries from exposure to laundry detergent pods. For the first time, this study sought to compare demographic and exposure characteristics and risk among children exposed to pod and non-pod laundry detergents presenting to emergency departments (EDs). METHODS: Data from the National Electronic Injury Surveillance System (NEISS) from 2012-2014 were used. All observations with injuries involving laundry detergent (NEISS code 0949) were included in this study...
June 23, 2016: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
Houmehr Hojjat, Peter F Svider, Ho-Sheng Lin, Adam J Folbe, Mahdi A Shkoukani, Jean Anderson Eloy, Giancarlo Zuliani
OBJECTIVES/HYPOTHESIS: To estimate the incidence of patients presenting to emergency departments (EDs) for facial trauma sustained from participation in combat sports and evaluate injury patterns and patient demographics. METHODS: The National Electronic Injury Surveillance System (NEISS) was evaluated for facial injuries from wrestling, boxing, and martial arts leading to ED visits from 2008 to 2013. Relevant entries were examined for injury mechanism, location, type, as well as other patient characteristics...
August 2016: Annals of Otology, Rhinology, and Laryngology
Cornelius A Thiels, Matthew C Hernandez, Martin D Zielinski, Johnathon M Aho
INTRODUCTION: Fishing is a common pastime. In the developed world, it is commonly performed as a recreational activity. We aim to determine injury patterns and outcomes among patients injured while ice fishing. METHODS: Data on initial emergency department visits from the National Electronic Injury Surveillance System-All Injury Program (NEISS-AIP) from 2009-2014 were analyzed. All patients with fishing related injuries were included. Primary endpoint was rate of admission or transfer...
July 2016: American Journal of Emergency Medicine
Alexander M Taylor, Rishi G Vaswani, Victor S Gehling, Michael C Hewitt, Yves Leblanc, James E Audia, Steve Bellon, Richard T Cummings, Alexandre Côté, Jean-Christophe Harmange, Hari Jayaram, Shivangi Joshi, Jose M Lora, Jennifer A Mertz, Adrianne Neiss, Eneida Pardo, Christopher G Nasveschuk, Florence Poy, Peter Sandy, Jeremy W Setser, Robert J Sims, Yong Tang, Brian K Albrecht
Inhibition of the bromodomains of the BET family, of which BRD4 is a member, has been shown to decrease myc and interleukin (IL) 6 in vivo, markers that are of therapeutic relevance to cancer and inflammatory disease, respectively. Herein we report substituted benzo[b]isoxazolo[4,5-d]azepines and benzotriazolo[4,3-d][1,4]diazepines as fragment-derived novel inhibitors of the bromodomain of BRD4. Compounds from these series were potent and selective in cells, and subsequent optimization of microsomal stability yielded representatives that demonstrated dose- and time-dependent reduction of plasma IL-6 in mice...
February 11, 2016: ACS Medicinal Chemistry Letters
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