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https://www.readbyqxmd.com/read/29135818/trends-of-magnet-ingestion-in-children-an-ironic-attraction
#1
Patrick Todd Reeves, Cade M Nylund, Jayasree Krishnamurthy, R Adam Noel, Mazen I Abbas
BACKGROUND AND OBJECTIVES: Ingestion of rare earth magnets is a serious ongoing hazard for pediatric patients. Our study aims to investigate whether 2012 Consumer Product Safety Commission (CPSC) policy action, in coordination with efforts from consumer and physician advocacy groups, decreased the incidence of magnet ingestions in children in US since 2012. METHODS: Data from the National Electronic Injury Surveillance System (NEISS) was used to evaluate trends in emergency department (ED) encounters with pediatric patients (<18 years) who presented with suspected magnet ingestions (SMI) from 2010-2015...
November 11, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29101814/injuries-associated-with-bunk-beds-that-occur-in-jail
#2
Randall T Loder, Jocelyn Cole Young
BACKGROUND: There are many studies of bunk bed injuries, but none specifically addressing those occurring in jails. It was the purpose of this study to investigate the magnitude and patterns of bunk bed injuries occurring in correctional institutions. METHODS: The National Electronic Injury Surveillance System (NEISS) data for the 10 year period 2006 through 2015 due to bunk beds was accessed. Injuries involving bunk beds were identified and the mechanism of injury determined...
October 20, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29049087/raising-mean-arterial-pressure-alone-restores-20-of-intraoperative-neuromonitoring-losses
#3
Joshua Yang, David L Skaggs, Priscella Chan, Suken A Shah, Michael G Vitale, Geraldine Neiss, Nicholas Feinberg, Lindsay M Andras
STUDY DESIGN: Multicenter prospective. OBJECTIVE: To assess the effect of intraoperative interventions in restoring intraoperative neuromonitoring (IONM) signals in pediatric spine surgery. SUMMARY OF BACKGROUND DATA: No prior studies have prospectively examined the rate of return of IONM signals by increasing blood pressure (BP) alone. METHODS: Patients undergoing posterior spinal deformity surgery were enrolled at their preoperative appointment...
October 18, 2017: Spine
https://www.readbyqxmd.com/read/29016427/comparison-of-intended-lengthening-of-magnetically-controlled-growing-rods-ultrasound-versus-x-ray
#4
Mutlu Cobanoglu, Suken A Shah, Peter Gabos, Kenneth Rogers, Petya Yorgova, Geraldine Neiss, Leslie Grissom, William G Mackenzie
BACKGROUND: In the treatment of early onset scoliosis (EOS), there has been a trend to use magnetically controlled growing rods (MCGR) in order to reduce the number of surgeries. To confirm the amount of lengthening, spine radiographs were required. Recently, ultrasound (US) has been added to monitor lengthening of MCGR to avoid radiation exposure. Our aim was to determine whether US is as accurate as plain radiography (x-ray) in determining the amount of length achieved at individual MCGR lengthening episodes...
October 9, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28980764/exploring-the-formation-of-black-phosphorus-intercalation-compounds-with-alkali-metals
#5
Gonzalo Abellán, Christian Neiss, Vicent Lloret, Stefan Wild, Julio C Chacón-Torres, Katharina Werbach, Filippo Fedi, Hidetsugu Shiozawa, Andreas Görling, Herwig Peterlik, Thomas Pichler, Frank Hauke, Andreas Hirsch
Black phosphorus intercalation compounds (BPICs) with alkali metals (namely: K and Na) have been synthesized in bulk by solid-state as well as vapor-phase reactions. By means of a combination of in situ X-ray diffraction, Raman spectroscopy, and DFT calculations the structural behavior of the BPICs at different intercalation stages has been demonstrated for the first time. Our results provide a glimpse into the very first steps of a new family of intercalation compounds, with a distinct behavior as compared to its graphite analogues (GICs), showing a remarkable structural complexity and a dynamic behavior...
October 5, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28945952/noncovalent-functionalization-and-charge-transfer-in-antimonene
#6
Gonzalo Abellán, Pablo Ares, Stefan Wild, Edurne Nuin, Christian Neiss, David Rodriguez-San Miguel, Pilar Segovia, Carlos Gibaja, Enrique G Michel, Andreas Görling, Frank Hauke, Julio Gómez-Herrero, Andreas Hirsch, Félix Zamora
Antimonene, a novel group 15 two-dimensional material, is functionalized with a tailormade perylene bisimide through strong van der Waals interactions. The functionalization process leads to a significant quenching of the perylene fluorescence, and surpasses that observed for either graphene or black phosphorus, thus allowing straightforward characterization of the flakes by scanning Raman microscopy. Furthermore, scanning photoelectron microscopy studies and theoretical calculations reveal a remarkable charge-transfer behavior, being twice that of black phosphorus...
September 25, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28837180/gallium-rich-pd-ga-phases-as-supported-liquid-metal-catalysts
#7
N Taccardi, M Grabau, J Debuschewitz, M Distaso, M Brandl, R Hock, F Maier, C Papp, J Erhard, C Neiss, W Peukert, A Görling, H-P Steinrück, P Wasserscheid
A strategy to develop improved catalysts is to create systems that merge the advantages of heterogeneous and molecular catalysis. One such system involves supported liquid-phase catalysts, which feature a molecularly defined, catalytically active liquid film/droplet layer adsorbed on a porous solid support. In the past decade, this concept has also been extended to supported ionic liquid-phase catalysts. Here we develop this idea further and describe supported catalytically active liquid metal solutions (SCALMS)...
September 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28783360/accurate-valence-ionization-energies-from-kohn-sham-eigenvalues-with-the-help-of-potential-adjustors
#8
Adrian Thierbach, Christian Neiss, Lukas Gallandi, Noa Marom, Thomas Körzdörfer, Andreas Görling
An accurate yet computationally very efficient and formally well justified approach to calculate molecular ionization potentials is presented and tested. The first as well as higher ionization potentials are obtained as the negatives of the Kohn-Sham eigenvalues of the neutral molecule after adjusting the eigenvalues by a recently [ Görling Phys. Rev. B 2015 , 91 , 245120 ] introduced potential adjustor for exchange-correlation potentials. Technically the method is very simple. Besides a Kohn-Sham calculation of the neutral molecule, only a second Kohn-Sham calculation of the cation is required...
September 14, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28752244/accuracy-of-3d-fluoro-navigated-anterior-transpedicular-screws-in-the-subaxial-cervical-spine-an-experimental-study-on-human-specimens
#9
Jan Bredow, C Meyer, F Siedek, W F Neiss, L Löhrer, L P Müller, P Eysel, G Stein
INTRODUCTION: Pedicle screw stabilization, the standard technique in the thoracic and lumbar spine, is increasingly used in the cervical spine. Initial studies on the use of anterior pedicle screws (ATPS) in the cervical spine have been recently published. ATPS use has theoretical advantages over posterior stabilization. We have already established a 3D-fluoroscopy navigation setup in a study of artificial bones. The aim of the current study was to evaluate the positioning quality/accuracy of ATPS introduced to human specimens...
November 2017: European Spine Journal
https://www.readbyqxmd.com/read/28740608/gne-886-a-potent-and-selective-inhibitor-of-the-cat-eye-syndrome-chromosome-region-candidate-2-bromodomain-cecr2
#10
Terry D Crawford, James E Audia, Steve Bellon, Daniel J Burdick, Archana Bommi-Reddy, Alexandre Côté, Richard T Cummings, Martin Duplessis, E Megan Flynn, Michael Hewitt, Hon-Ren Huang, Hariharan Jayaram, Ying Jiang, Shivangi Joshi, James R Kiefer, Jeremy Murray, Christopher G Nasveschuk, Arianne Neiss, Eneida Pardo, F Anthony Romero, Peter Sandy, Robert J Sims, Yong Tang, Alexander M Taylor, Vickie Tsui, Jian Wang, Shumei Wang, Yongyun Wang, Zhaowu Xu, Laura Zawadzke, Xiaoqin Zhu, Brian K Albrecht, Steven R Magnuson, Andrea G Cochran
The biological function of bromodomains, epigenetic readers of acetylated lysine residues, remains largely unknown. Herein we report our efforts to discover a potent and selective inhibitor of the bromodomain of cat eye syndrome chromosome region candidate 2 (CECR2). Screening of our internal medicinal chemistry collection led to the identification of a pyrrolopyridone chemical lead, and subsequent structure-based drug design led to a potent and selective CECR2 bromodomain inhibitor (GNE-886) suitable for use as an in vitro tool compound...
July 13, 2017: ACS Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28670666/epidemiologic-comparisons-of-soccer-related-injuries-presenting-to-emergency-departments-and-reported-within-high-school-and-collegiate-settings
#11
Zachary Y Kerr, Lauren A Pierpoint, Dustin W Currie, Erin B Wasserman, R Dawn Comstock
BACKGROUND: Few studies compare sports injury patterns in different settings. This study described the epidemiology of soccer injuries presenting to emergency departments (EDs) and compared injuries presenting to EDs to injuries presenting to collegiate and high school athletic trainers (ATs). METHODS: Soccer-related injuries (product code 1267) in the National Electronic Injury Surveillance System (NEISS) that were sustained by individuals at least two years of age in 2004-2013 were included...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28612296/kinesin-5-blocker-monastrol-protects-against-bortezomib-induced-peripheral-neurotoxicity
#12
Ilja Bobylev, Dominik Peters, Maulik Vyas, Mohammed Barham, Ines Klein, Elke Pogge von Strandmann, Wolfram F Neiss, Helmar C Lehmann
Neurotoxicity is a relevant side effect of bortezomib treatment. Previous reports have shown that the development of peripheral neuropathy caused by anti-neoplastic agents may be a result of reduced axonal transport. Based on evidence from prior studies that the kinesin-5 inhibitor monastrol enhances axonal transport and improves neuronal regeneration, we focused on the neuroprotective role of monastrol during the chemotherapeutic treatment with bortezomib. Prolonged treatment of C57BL/6 mice with bortezomib induced a length-dependent small-fiber neuropathy with axonal atrophy and loss of sensory nerve fibers...
June 13, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/28609945/-i-gynacantha-i-i-dryadula-i-sp-nov-from-the-guiana-shield-odonata-anisoptera-aeshnidae
#13
Ulisses Gaspar Neiss, Jürg DE Marmels
The new species is described and illustrated on the basis of two reared, subteneral males from Brazil, their larval exuviae, a mature male from French Guiana, a mature female from Venezuela, and a mature female from Surinam. One of the Brazilian males is the holotype (BRAZIL, Amazonas State, Manaus, Reserva Florestal Ducke, BR 174-km 26, trail to Acará creek, 02º55'47"S, 59º58'22"W, 0.7 m elevation, deposited in INPA). The new species (total length 50-54 mm) differs from other small species of same genus by color pattern of thorax, middle and hind tibiae dark with external (dorsal) yellow streak, male cercus with truncated tip lacking apical spine, and male epiproct reaching or slightly surpassing midlength of cercus...
April 20, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609379/pediatric-moped-related-injuries-in-the-united-states-from-2002-to-2014-age-related-comparisons-of-mechanisms-and-outcomes
#14
Nathaniel K Johnson, Brandon M Johnson, Gerene M Denning, Charles A Jennissen
Mopeds are a popular means of transportation, especially in urban areas. However, few studies have investigated moped-related injuries in the United States. This study's goal was to compare the crash mechanisms and injuries suffered in moped-related crashes involving youth versus adults, as well as between younger and older children. INTRODUCTION: Mopeds are a popular means of transportation, especially in urban areas. However, few studies have investigated moped-related injuries in the United States...
November 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28598951/the-impact-of-legislation-on-gas-can-and-mattress-related-burn-injuries
#15
Kellogg Levi, Butcher Brandon, Peek-Asa Corinne, Wibbenmeyer Lucy
Burn prevention program success requires thorough evaluation of intervention outcomes. The impact of 2 engineering-specific burn prevention regulations, the Children's Gasoline Burn Prevention Act, and the Standard for the Flammability of Mattress Sets will be assessed. Records from 1997 to 2015 within the Consumer Product Safety Commission's (CPSC) National Electronic Injury Surveillance System (NEISS) were reviewed. After identifying gas can- and mattress-involved burn injuries, injury incidence was estimated by utilizing survey sampling weights associated with each record...
June 6, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28406787/factors-influencing-helmet-use-head-injury-and-hospitalization-among-children-involved-in-skateboarding-and-snowboarding-accidents
#16
Homa Sadeghian, Brian Nguyen, Nhan Huynh, Joshua Rouch, Steven L Lee, Shahrzad Bazargan-Hejazi
CONTEXT: Up to 75% of skateboarders and snowboarders admitted to the hospital sustain head injuries. It is unclear why not all children and teenagers wear helmets while snowboarding and skateboarding given the protection they afford. OBJECTIVES: To report on the prevalence of, and factors associated with, skateboarding and snowboarding in injured children and to explore factors that influence helmet use, head injury, and hospitalization in this sample. DESIGN: A cross-sectional study of skateboard- and snowboard-associated injuries from 2003 to 2012 among individuals younger than age 18 years using National Electronic Injury Surveillance System (NEISS) data from approximately 100 hospitals...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28372790/hoverboards-a-new-cause-of-pediatric-morbidity
#17
Brianna L Siracuse, Joseph A Ippolito, Peter D Gibson, Kathleen S Beebe
INTRODUCTION: The hoverboard, a self-balancing powered scooter, was introduced to the market in 2015 and quickly became one of the most popular purchases of the year. As with similar products, this scooter brought a host of concerns surrounding injuries. The purpose of this study is to determine the incidence of injuries that coincided with the popularity of hoverboard. METHODS: The National Electronic Injury Surveillance System (NEISS) was queried from 2011 through 2015 for injuries related to scooters/skateboards, powered (product number, 5042), which includes the hoverboard...
March 27, 2017: Injury
https://www.readbyqxmd.com/read/28238092/radial-shortening-osteotomy-reduces-radiocapitellar-contact-pressures-while-preserving-valgus-stability-of-the-elbow
#18
Michael Hackl, Kilian Wegmann, Stephanie L Kahmann, Nicolai Heinze, Manfred Staat, Wolfram F Neiss, Martin Scaal, Lars P Müller
PURPOSE: Shortening osteotomy of the proximal radius might represent a potential salvage procedure in symptomatic radiocapitellar osteoarthritis, which could decrease radiocapitellar load while preserving the native radial head. In an in-vitro biomechanical investigation, we sought to determine whether shortening osteotomy of the proximal radius (1) decreases the radiocapitellar joint pressure upon axial loading and (2) retains valgus stability of the elbow. In addition, the anatomic configuration of the lesser sigmoid notch was evaluated to assess possible contraindications...
July 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28110471/depletion-of-mitofusin-2-causes-mitochondrial-damage-in-cisplatin-induced-neuropathy
#19
Ilja Bobylev, Abhijeet R Joshi, Mohammed Barham, Wolfram F Neiss, Helmar C Lehmann
Sensory neuropathy is a relevant side effect of the antineoplastic agent cisplatin. Mitochondrial damage is assumed to play a critical role in cisplatin-induced peripheral neuropathy, but the pathomechanisms underlying cisplatin-induced mitotoxicity and neurodegeneration are incompletely understood. In an animal model of cisplatin-induced neuropathy, we determined in detail the extent and spatial distribution of mitochondrial damage during cisplatin treatment. Changes in the total number of axonal mitochondria during cisplatin treatment were assessed in intercostal nerves from transgenic mice that express cyan fluorescent protein...
January 21, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28097520/extremity-fractures-associated-with-atvs-and-dirt-bikes-a-10-year-national-epidemiologic-study
#20
D J Lombardo, T Jelsema, A Gambone, M Weisman, G Petersen-Fitts, J D Whaley, V J Sabesan
BACKGROUND: Morbidity and mortality of all-terrain vehicles and dirt bikes have been studied, as well as the association of helmet use and head injury. HYPOTHESIS/PURPOSE: The purpose of this study is to compare and contrast the patterns of extremity fractures associated with ATVs and dirt bikes. We believe there will be unique and potentially preventable injury patterns associated with dirt bikes and three-wheeled ATVs due to the poor stability of these vehicles...
August 2017: Musculoskeletal Surgery
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