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https://www.readbyqxmd.com/read/28945025/-dna-marker-assisted-selection-of-medicinal-plants-%C3%A2-breeding-research-of-disease-resistant-cultivars-of-panax-notoginseng
#1
Lin-Lin Dong, Zhong-Jian Chen, Yong Wang, Fu-Gang Wei, Lian-Juan Zhang, Jiang Xu, Guang-Fei Wei, Rui Wang, Juan Yang, Wei-Lin Liu, Xi-Wen Li, Yu-Qi Yu, Shi-Lin Chen
DNA marker-assisted selection of medicinal plants is based on the DNA polymorphism, selects the DNA sequences related to the phenotypes such as high yields, superior quality, stress-resistance and so on according to the technologies of molecular hybridization, polymerase chain reaction and high-throughput sequencing, and assists the breeding of new cultivars. This study bred the first disease-resistant cultivar of notoginseng "Miaoxiang Kangqi 1" using the technology of DNA marker-assisted selection of medicinal plants and systematic breeding...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28945017/-a-strategy-of-constructing-the-technological-system-for-quality-control-of-chinese-medicine-based-on-process-control-and-management
#2
Yi-Yu Cheng, Zhong-Zhi Qian, Bo-Li Zhang
The current situation, bottleneck problems and severe challenges in quality control technology of Chinese Medicine (CM) are briefly described. It is presented to change the phenomenon related to the post-test as the main means and contempt for process control in drug regulation, reverse the situation of neglecting the development of process control and management technology for pharmaceutical manufacture and reconstruct the technological system for quality control of CM products. The regulation and technology system based on process control and management for controlling CM quality should be established to solve weighty realistic problems of CM industry from the root causes, including backwardness of quality control technology, weakness of quality risk control measures, poor reputation of product quality and so on...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28944960/application-of-high-pressure-homogenization-on-gums-a-review
#3
REVIEW
Ricardo Henrique Belmiro, Alline Artigiani Lima Tribst, Marcelo Cristianini
High pressure homogenization (HPH) is an emerging process in which a fluid product is pumped by pressure intensifiers forcing it to flows through a narrow gap, usually measured in the order of micrometers. Gums are polysaccharides from vegetal, animal or microbial origin, widely employed in food and chemical industries as thickeners, stabilizers, gelling agents and emulsifiers. Choosing a specific gum will depend on its application and purpose, as each form of gum has particular values for viscosity, intrinsic viscosity, stability, emulsifying and gelling properties, being these parameters determined by its structure...
September 25, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28944816/decoration-of-reduced-graphene-oxide-by-gold-nanoparticles-an-enhanced-negative-photoconductivity
#4
Qi Wang, Yudi Tu, Takashi Ichii, Toru Utsunomiya, Hiroyuki Sugimura, Lifeng Hao, Rongguo Wang, Xiaodong He
Photodetection in a visible light region is important in various applications, including computation, environmental monitoring, biological detection and industrial control. Due to this, research studies to develop photoconductive devices have great significance. We report a study on the photoconductivity of reduced graphene oxide (rGO)/gold nanoparticle (AuNP) nanocomposites, emphasizing the enhancement effect induced by AuNPs. rGO/AuNP photoelectric devices were prepared by spincoating rGO onto an AuNP-array-covered silicon substrate...
September 25, 2017: Nanoscale
https://www.readbyqxmd.com/read/28944761/biodegradable-zein-polydopamine-polymeric-scaffold-impregnated-with-tio2-nanoparticles-for-skin-tissue-engineering
#5
S Babitha, Purna Sai Korrapati
Polymers from renewable resources are attractive for various industrial and biomedical applications owing to their compatibility, degradability, ease of use and availability. Rapid progress in the development of nanotechnology has improved the characteristic features of polymers in composite materials by reinforcing the nanosized particulates during fabrication. In this study, we have attempted to incorporate metal oxide nanoparticles into polymeric nanofibers in order to enhance the overall properties of the composite scaffold...
September 25, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28944738/an-industry-update-the-latest-developments-in-therapeutic-delivery
#6
Oliver C Steinbach
The present industry update covers the period 1-30 June 2017, with information sourced from company press releases, regulatory and patent agencies as well as scientific literature. The combination of drug and devices such as improved, safer injectables (see various market reports, companies Adamis and Baxter), patches (Microdermis) and (nano)carriers are moving increasingly from the R&D stage into clinical trials and toward the market. This addresses increased safety and effectiveness requirements, limiting physico-chemical properties of active ingredients, cost-effectiveness and patient comfort through ease of use...
October 2017: Therapeutic Delivery
https://www.readbyqxmd.com/read/28944730/optimization-of-medication-use-at-accountable-care-organizations
#7
Chrisanne Wilks, Erik Krisle, Kimberly Westrich, Kristina Lunner, David Muhlestein, Robert Dubois
BACKGROUND: Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES: To (a) assess how ACOs optimize medication use; (b) establish an association between efforts to optimize medication use and achievement on financial and quality metrics; (c) identify organizational factors that correlate with optimized medication use; and (d) identify barriers to optimized medication use...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944693/implementation-of-automatic-external-defibrillator-using-real-time-ventricular-fibrillation-detecting-algorithm-based-on-time-domain-analysis
#8
Ki Woong Seong, Sung Dae Na, Young Sik Park, Hee-Joon Park, Myoung Nam Kim, Jin-Ho Cho, Jyung Hyun Lee
The increase in mortality associated with arrhythmia is an inevitable problem of modern society such as westernized eating habits and an increase in stress due to industrialization, and the related social costs are increasing. In this regard, the supply of automatic external defibrillator (AED) used outside hospitals is increasing mainly in public institutions, and AED is a medical practice performed by non-medical personnel. Therefore, studies on arrhythmia detection algorithm to make accurate clinical judgment for proper use are increasing...
September 25, 2017: Computer Assisted Surgery (Abingdon, England)
https://www.readbyqxmd.com/read/28944604/the-social-practice-of-medical-guanxi-personal-connections-and-patient-physician-trust-in-china-an-anthropological-and-ethical-tsudy
#9
Xiang Zou, Yu Cheng, Jing-Bao Nie
In China's healthcare sector, a popular and socio-culturally distinctive phenomenon known as guanxi jiuyi (medical guanxi), whereby patients draw on their guanxi (personal connections) with physicians when seeking healthcare, is thriving. Integrating anthropological investigation with normative inquiry, this paper examines medical guanxi through the lens of patient-physician trust and mistrust. The first-hand empirical data acquired - on the lived experiences and perspectives of both patients and physicians - is based on six months' fieldwork carried out in a county hospital in Guangdong, southern China, which included in-depth interviews with 20 patients and 20 medical professionals...
September 25, 2017: Developing World Bioethics
https://www.readbyqxmd.com/read/28944602/hepatitis-e-virus-and-related-viruses-in-wild-domestic-and-zoo-animals-a-review
#10
REVIEW
C Spahr, T Knauf-Witzens, T Vahlenkamp, R G Ulrich, R Johne
Hepatitis E is a human disease mainly characterized by acute liver illness, which is caused by infection with the hepatitis E virus (HEV). Large hepatitis E outbreaks have been described in developing countries; however, the disease is also increasingly recognized in industrialized countries. Mortality rates up to 25% have been described for pregnant women during outbreaks in developing countries. In addition, chronic disease courses could be observed in immunocompromised transplant patients. Whereas the HEV genotypes 1 and 2 are mainly confined to humans, genotypes 3 and 4 are also found in animals and can be zoonotically transmitted to humans...
September 24, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28944536/transcriptomic-repertoires-depict-the-initiation-of-lint-and-fuzz-fibers-in-cotton-gossypium-hirsutum-l
#11
Haiyan Hu, Maojun Wang, Yuanhao Ding, Sitao Zhu, Guannan Zhao, Lili Tu, Xianlong Zhang
Cotton fiber is an important natural fiber for the textile industry. The number of fiber initials determines the lint percentage, which is an important factor for cotton fiber yield. Although fiber development has been described by transcriptomic analysis, the mechanism by which the long non-coding RNA manipulate the initiation of lint and fuzz fibers remains unknown. In this study, three lines with different lint percentages were developed by crossing Xu142 with its fiberless mutant Xu142 fl. We collected the epidermal cells from the ovules with attached fibers at 0 and 5 days post-anthesis (DPA) from Xu142, the fiberless mutant Xu142 fl and the three lint percent diversified lines for deep transcriptome sequencing...
September 25, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28944384/pd-c-core-shell-nanoparticles-on-carbon-nanotubes-as-highly-stable-and-selective-catalysts-for-hydrogenation-of-acetylene-to-ethylene
#12
Liyun Zhang, Yuxiao Ding, Kuang-Hsu Wu, Yiming Niu, Jingjie Luo, Xikun Yang, Bingsen Zhang, Dangsheng Su
Developing highly selective and stable catalysts for acetylene hydrogenation is an imperative task in the chemical industry. Herein, core-shell Pd@carbon nanoparticles supported on carbon nanotubes (Pd@C/CNTs) were synthesized. During the hydrogenation of acetylene, the selectivity of Pd@C/CNTs to ethylene was distinctly improved. Moreover, Pd@C/CNTs showed excellent stability during the hydrogenation reaction.
September 25, 2017: Nanoscale
https://www.readbyqxmd.com/read/28944012/assessing-the-effects-of-the-first-2%C3%A2-years-of-industry-led-badger-culling-in-england-on-the-incidence-of-bovine-tuberculosis-in-cattle-in-2013-2015
#13
Lucy A Brunton, Christl A Donnelly, Heather O'Connor, Alison Prosser, Stuart Ashfield, Adam Ashton, Paul Upton, Andrew Mitchell, Anthony V Goodchild, Jessica E Parry, Sara H Downs
Culling badgers to control the transmission of bovine tuberculosis (TB) between this wildlife reservoir and cattle has been widely debated. Industry-led culling began in Somerset and Gloucestershire between August and November 2013 to reduce local badger populations. Industry-led culling is not designed to be a randomized and controlled trial of the impact of culling on cattle incidence. Nevertheless, it is important to monitor the effects of the culling and, taking the study limitations into account, perform a cautious evaluation of the impacts...
September 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28943868/microbial-shifts-in-the-intestinal-microbiota-of-salmonella-infected-chickens-in-response-to-enrofloxacin
#14
Jun Li, Haihong Hao, Guyue Cheng, Chunbei Liu, Saeed Ahmed, Muhammad A B Shabbir, Hafiz I Hussain, Menghong Dai, Zonghui Yuan
Fluoroquinolones (FQs) are important antibiotics used for treatment of Salmonella infection in poultry in many countries. However, oral administration of fluoroquinolones may affect the composition and abundance of a number of bacterial taxa in the chicken intestine. Using 16S rRNA gene sequencing, the microbial shifts in the gut of Salmonella infected chickens in response to enrofloxacin treatments at different dosages (0, 0.1, 4, and 100 mg/kg b.w.) were quantitatively evaluated. The results showed that the shedding levels of Salmonella were significantly reduced in the high dosage group as demonstrated by both the culturing method and 16S rRNA sequencing method...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28943864/evolutionary-engineering-in-chemostat-cultures-for-improved-maltotriose-fermentation-kinetics-in-saccharomyces-pastorianus-lager-brewing-yeast
#15
Anja Brickwedde, Marcel van den Broek, Jan-Maarten A Geertman, Frederico Magalhães, Niels G A Kuijpers, Brian Gibson, Jack T Pronk, Jean-Marc G Daran
The lager brewing yeast Saccharomyces pastorianus, an interspecies hybrid of S. eubayanus and S. cerevisiae, ferments maltotriose, maltose, sucrose, glucose and fructose in wort to ethanol and carbon dioxide. Complete and timely conversion ("attenuation") of maltotriose by industrial S. pastorianus strains is a key requirement for process intensification. This study explores a new evolutionary engineering strategy for improving maltotriose fermentation kinetics. Prolonged carbon-limited, anaerobic chemostat cultivation of the reference strain S...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28943759/use-of-atmospheric-pressure-cold-plasma-for-meat-industry
#16
Juri Lee, Cheol Woo Lee, Hae In Yong, Hyun Jung Lee, Cheorun Jo, Samooel Jung
Novel, effective methods to control and prevent spoilage and contamination by pathogenic microorganisms in meat and meat products are in constant demand. Non-thermal pasteurization is an ideal method for the preservation of meat and meat products because it does not use heat during the pasteurization process. Atmospheric pressure cold plasma (APCP) is a new technology for the non-thermal pasteurization of meat and meat products. Several recent studies have shown that APCP treatment reduces the number of pathogenic microorganisms in meat and meat products...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/28943461/the-importance-of-sourcing-enzymes-from-non-conventional-fungi-for-metabolic-engineering-biomass-breakdown
#17
REVIEW
Susanna Seppälä, St Elmo Wilken, Doriv Knop, Kevin V Solomon, Michelle A O'Malley
A wealth of fungal enzymes has been identified from nature, which continue to drive strain engineering and bioprocessing for a range of industries. However, while a number of clades have been investigated, the vast majority of the fungal kingdom remains unexplored for industrial applications. Here, we discuss selected classes of fungal enzymes that are currently in biotechnological use, and explore more basal, non-conventional fungi and their underexploited biomass-degrading mechanisms as promising agents in the transition towards a bio-based society...
September 21, 2017: Metabolic Engineering
https://www.readbyqxmd.com/read/28943440/molecular-imprinted-chitosan-tio2-nanocomposite-for-the-selective-removal-of-rose-bengal-from-wastewater
#18
Mohamed A Ahmed, Nader M Abdelbar, Ashraf A Mohamed
A new molecularly imprinted polymer (MIP) chitosan-TiO2 nanocomposite (CTNC) was prepared for the selective and quantitative removal of Rose Bengal dye from industrial wastewater. The physicochemical features of the prepared CTNC-MIP nanoparticles were thoroughly investigated. The prepared MIP nanoparticles exhibited high surface area (95.38m(2)/g) with relatively uniform mesoporous channels that allowed an exceptional uptake of the dye (qm=79.365mg/g) and reflected the high selectivity of the prepared MIP compared to pure chitosan...
September 21, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28943301/in-vivo-production-of-recombinant-proteins-using-occluded-recombinant-acmnpv-derived-baculovirus-vectors
#19
Eva Guijarro-Pardo, Silvia Gómez-Sebastián, José M Escribano
Trichoplusia ni insect larvae infected with vectors derived from the Autographa californica multiple nucleopolyhedrovirus (AcMNPV), are an excellent alternative to insect cells cultured in conventional bioreactors to produce recombinant proteins because productivity and cost-efficiency reasons. However, there is still a lot of work to do to reduce the manual procedures commonly required in this production platform that limit its scalability. To increase the scalability of this platform technology, a current bottleneck to be circumvented in the future is the need of injection for the inoculation of larvae with polyhedrin negative baculovirus vectors (Polh-) because of the lack of oral infectivity of these viruses, which are commonly used for production in insect cell cultures...
September 21, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28943206/kaolinite-in-pharmaceutics-and-biomedicine
#20
REVIEW
Mahmoud E Awad, Alberto López-Galindo, Massimo Setti, Mahmoud M El-Rahmany, César Viseras Iborra
Kaolinite Al2Si2O5(OH)4 is an abundant and inexpensive geomaterial regarded as one of the most common clay minerals in the earth's crust and the most widespread phase among the other kaolin polymorphs (halloysite, dickite and nacrite). Structurally, it is a hydrous aluminum phyllosilicate member belonging to the dioctahedral 1:1 kaolin mineral group. The particle size of the pseudohexagonal kaolinite platelets is normally <2μm (if compared to a human red blood cell of a typical diameter 6.2-8.2μm or to a virus particle of about 50nm diameter)...
September 21, 2017: International Journal of Pharmaceutics
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