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https://www.readbyqxmd.com/read/28449354/prevalence-of-and-work-related-risk-factors-for-hand-eczema-in-a-norwegian-general-population-the-hunt-study
#1
Hilde K Vindenes, Cecilie Svanes, Stein H L Lygre, Bjørg-Eli Hollund, Arnulf Langhammer, Randi J Bertelsen
BACKGROUND: Chemical exposures at work and at home may cause hand eczema. However, this has been scarcely described for Norway. OBJECTIVES: To investigate the prevalence of, and occupational risk factors for, hand eczema in Norway. METHODS: Among 50 805 respondents (aged ≥20 years) to the third Nord-Trøndelag Health Study (HUNT3), 5757 persons reported ever having hand eczema, and 4206 answered a hand eczema questionnaire. RESULTS: The lifetime prevalences of hand eczema were 8...
April 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28449298/all-silicon-switchable-magnetoelectric-effect-via-interlayer-exchange-coupling
#2
Hang Liu, Jia Tao Sun, Huixia Fu, Peijie Sun, Yuanping Feng, Sheng Meng
The magnetoelectric (ME) effect originating from the effective coupling between electric field and magnetism is an exciting frontier in nanoscale science such as magnetic tunneling junction (MTJ), ferroelectric/piezoelectric heterojunctions etc. The realization of switchable ME effect under external electric field in d^0 semiconducting materials of single composition is needed especially for all-silicon spintronics applications because of its natural compatibility with current industry. We employ the density functional theory (DFT) to reveal that the pristine Si(111)-√3×√3R30º (Si√3 hereafter) reconstructed surfaces of thin films with thickness smaller than eleven bilayers support sizeable linear ME effect with switchable direction of magnetic moment under external electric field...
April 27, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28449101/synthetic-biology-approaches-for-the-production-of-plant-metabolites-in-unicellular-organisms
#3
Tessa Moses, Payam Mehrshahi, Alison G Smith, Alain Goossens
Synthetic biology is the repurposing of biological systems for novel objectives and applications. Through the co-ordinated and balanced expression of genes, both native and those introduced from other organisms, resources within an industrial chassis can be siphoned for the commercial production of high-value commodities. This developing interdisciplinary field has the potential to revolutionize natural product discovery from higher plants, by providing a diverse array of tools, technologies, and strategies for exploring the large chemically complex space of plant natural products using unicellular organisms...
April 25, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28449002/purification-and-biochemical-and-kinetic-properties-of-an-endo-polygalacturonase-from-the-industrial-fungus-aspergillus-sojae
#4
Dante Fratebianchi, Ivana Alejandra Cavello, Sebastián Fernando Cavalitto
An endo-polygalacturonase secreted by Aspergillus sojae was characterized after being purified to homogeneity from submerged cultures with orange peel as the sole carbon source by gel filtration and ion-exchange chromatographies. According to SDS-PAGE and analytical isoelectric focusing analyses, the enzyme presents a molecular weight of 47 kDa and pI value of 4.2. This enzyme exhibits considerable stability under highly acidic to neutral conditions (pH 1.5-6.5) and presents a half-life of 2 h at 50°C. Besides its activity towards pectin and polygalacturonic acid, the enzyme displays pectin-releasing activity, acting best in a pH range of 3...
April 28, 2017: Journal of Molecular Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28448939/environmental-impacts-of-producing-bioethanol-and-biobased-lactic-acid-from-standalone-and-integrated-biorefineries-using-a-consequential-and-an-attributional-life-cycle-assessment-approach
#5
Ranjan Parajuli, Marie Trydeman Knudsen, Morten Birkved, Sylvestre Njakou Djomo, Andrea Corona, Tommy Dalgaard
This study evaluates the environmental impacts of biorefinery products using consequential (CLCA) and attributional (ALCA) life cycle assessment (LCA) approaches. Within ALCA, economic allocation method was used to distribute impacts among the main products and the coproducts, whereas within the CLCA system expansion was adopted to avoid allocation. The study seeks to answer the questions (i) what is the environmental impacts of process integration?, and (ii) do CLCA and ALCA lead to different conclusions when applied to biorefinery?...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448938/choice-modeling-of-system-wide-or-large-scale-environmental-change-in-a-developing-country-context-lessons-from-the-para%C3%A3-ba-do-sul-river
#6
James R Kahn, William F Vásquez, Carlos Eduardo de Rezende
The Rio Paraiba do Sul is a highly polluted river in south central Brazil, that is contaminated by industrial, agricultural and municipal wastes, as well as being impacted by dams, water withdrawals and deforestation in the watershed. Since only very intensive and farreaching environmental policies could result in water quality improvements, valuing the restoration of the river presents many unique challenges. We develop a choice-modeling approach to valuation of the restoration of this river, with general tightening of environmental policy as the policy, and an increase in prices as the payment vehicle...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448933/in-vitro-bioaccessibility-of-copper-azole-following-simulated-dermal-transfer-from-pressure-treated-wood
#7
Jennifer L Griggs, Kim R Rogers, Clay Nelson, Todd Luxton, William E Platten, Karen D Bradham
Micronized copper azole (MCA) and micronized copper quaternary (MCQ) are the latest wood preservatives to replace the liquid alkaline copper and chromated copper arsenate preservatives due to concerns over the toxicity or lack of effectiveness of the earlier formulations. Today, the use of MCA has become abundant in the wood preservative industry with approximately 38millionlbs of copper carbonate being used to treat lumber each year. Despite this widespread usage, little information is available on the bioaccessibility of this preservative upon gastrointestinal exposure...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448928/potential-environmental-impact-of-bioethanol-production-chain-from-fiber-sorghum-to-be-used-in-passenger-cars
#8
Annachiara Forte, Amalia Zucaro, Massimo Fagnano, Angelo Fierro
A life cycle assessment (LCA) was applied to assess the environmental load of a prospective local bioethanol (EtOH) production system in Southern Italy by using lignocellulosic Fiber sorghum (FS) feedstock. A two steps analysis was carried out considering: (i) a "cradle-to-farm gate" LCA to investigate thoroughly the FS cultivation on hilly marginal land and (ii) a "cradle-to-wheels" system boundary encompassing the environmental pressure of the whole EtOH supply-use chain. Primary data related to lignocellulosic biomass production were combined with experimental feedstock conversion processes through advanced second generation technology...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448907/characterization-of-typical-metal-particles-during-haze-episodes-in-shanghai-china
#9
Rui Li, Xin Yang, Hongbo Fu, Qingqing Hu, Liwu Zhang, Jianmin Chen
Aerosol particles were collected during three heavy haze episodes at Shanghai in the winter of 2013. Transmission electron microscopy (TEM) coupled with energy dispersive X-ray spectroscopy was used to study the morphology and speciation of typical metal particles at a single-particle level. In addition, time-of-flight aerosol mass spectrometry (ATOFMS) was applied to identify the speciation of the Fe-containing particles. TEM analysis indicated that various metal-containing particles were hosted by sulfates, nitrates, and oxides...
April 19, 2017: Chemosphere
https://www.readbyqxmd.com/read/28448854/the-combined-use-of-analytical-tools-for-exploring-tetanus-toxin-and-tetanus-toxoid-structures
#10
Caroline Bayart, Sébastien Peronin, Elisa Jean, Joseph Paladino, Philippe Talaga, Marc Le Borgne
Aldehyde detoxification is a process used to convert toxin into toxoid for vaccine applications. In the case of tetanus toxin (TT), formaldehyde is used to obtain the tetanus toxoid (TTd), which is used either for the tetanus vaccine or as carrier protein in conjugate vaccines. Several studies have already been conducted to better understand the exact mechanism of this detoxification. Those studies led to the identification of a number of formaldehyde-induced modifications on lab scale TTd samples. To obtain greater insights of the changes induced by formaldehyde, we used three industrial TTd batches to identify repeatable modifications in the detoxification process...
April 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28448845/use-of-aqueous-two-phase-peg-salt-systems-for-the-removal-of-anionic-surfactant-from-effluents
#11
Gabriella Frade Murari, Jussara Alves Penido, Heriveltom Morais da Silva, Bruno Eduardo Lôbo Baêta, Sérgio Francisco de Aquino, Leandro Rodrigues de Lemos, Guilherme Dias Rodrigues, Aparecida Barbosa Mageste
Linear alkylbenzene sulfonates (LAS) are synthetic anionic surfactants that are extensively used in many industries. As a result, large volumes of effluents containing high levels of these compounds are discharged into water bodies, causing risks to aquatic flora and fauna. Then, there is a need for environmentally safe and economically viable technologies for the removal of LAS from aqueous matrices. The present work evaluates the use of aqueous two-phase systems (ATPS) composed of PEG and sulfate salts for this purpose, considering the effects of tie line length (TLL), molar mass of polymer, and type of cation-forming salt on the partitioning behavior of LAS...
April 24, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28448834/cmc-prediction-for-ionic-surfactants-in-pure-water-and-aqueous-salt-solutions-based-solely-on-tabulated-molecular-parameters
#12
Stoyan I Karakashev, Stoyan K Smoukov
The critical micelle concentration (CMC) of various surfactants is difficult to predict accurately, yet often necessary to do in both industry and science. Hence, quantum-chemical software packages for precise calculation of CMC were developed, but they are expensive and time consuming. We show here an easy method for calculating CMC with a reasonable accuracy. Firstly, CMC0 (intrinsic CMC, absent added salt) was coupled with quantitative structure - property relationship (QSPR) with defined by us parameter "CMC predictor" f1...
April 18, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28448811/effect-of-addition-of-sewage-sludge-and-coal-sludge-on-bioavailability-of-selected-metals-in-the-waste-from-the-zinc-and-lead-industry
#13
Jolanta Sobik-Szołtysek, Katarzyna Wystalska, Anna Grobelak
This study evaluated the content of bioavailable forms of selected heavy metals present in the waste from Zn and Pb processing that can potentially have an effect on the observed difficulties in reclamation of landfills with this waste. The particular focus of the study was on iron because its potential excess or deficiency may be one of the causes of the failure in biological reclamation. The study confirmed that despite high content of total iron in waste (mean value of 200.975gkg(-1)), this metal is present in the forms not available to plants (mean: 0...
April 24, 2017: Environmental Research
https://www.readbyqxmd.com/read/28448782/amcp-partnership-forum-driving-value-and-outcomes-in-oncology
#14
(no author information available yet)
Innovation in cancer treatment has provided a wealth of recently available therapeutic agents and a healthy drug pipeline that promises to change the way we approach this disease and the lives of those affected in the years to come. However, the majority of these new agents, many of which are targeted to specific genomic features of various tumors, may challenge the health care system's ability to afford cancer care. This innovation drives the need to focus on the value of the treatments provided to patients with cancer and on methods to optimize the efficiency of the dollars we spend, in addition to the clinical value itself...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28448745/medium-optimization-for-pyrroloquinoline-quinone-pqq-production-by-methylobacillus-sp-zju323-using-response-surface-methodology-and-artificial-neural-network-genetic-algorithm
#15
Peilian Wei, Zhenjun Si, Yao Lu, Qingfei Yu, Lei Huang, Zhinan Xu
Methylobacillus sp. zju323 was adopted to improve the biosynthesis of pyrroloquinoline quinone (PQQ) by systematic optimization of the fermentation medium. The Plackett-Burman design (PBD) was implemented to screen for the key medium components for the PQQ production. CoCl2 · 6H2O, ρ-amino benzoic acid (PABA), and MgSO4 · 7H2O were found capable of enhancing the PQQ production most significantly. A five level-three factor central composite design (CCD) was employed to investigate the direct and interactive effects of these variables...
April 27, 2017: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/28448543/heterologous-expression-of-a-thermophilic-diacylglycerol-acyltransferase-triggers-triglyceride-accumulation-in-escherichia-coli
#16
Beatriz Lázaro, Juan A Villa, Omar Santín, Matilde Cabezas, Cintia D F Milagre, Fernando de la Cruz, Gabriel Moncalián
Triglycerides (TAGs), the major storage molecules of metabolic energy and source of fatty acids, are produced as single cell oil by some oleogenic microorganisms. However, these microorganisms require strict culture conditions, show low carbon source flexibilities, lack efficient genetic modification tools and in some cases pose safety concerns. TAGs have essential applications such as behaving as a source for added-value fatty acids or giving rise to the production of biodiesel. Hence, new alternative methods are urgently required for obtaining these oils...
2017: PloS One
https://www.readbyqxmd.com/read/28448481/occupational-fatalities-resulting-from-falls-in-the-oil-and-gas-extraction-industry-united-states-2005-2014
#17
Krystal L Mason, Kyla D Retzer, Ryan Hill, Jennifer M Lincoln
During 2003-2013, fatality rates for oil and gas extraction workers decreased for all causes of death except those associated with fall events, which increased 2% annually during 2003-2013 (1). To better understand risk factors for these events, CDC examined fatal fall events in the oil and gas extraction industry during 2005-2014 using data from case investigations conducted by the Occupational Safety and Health Administration (OSHA). Sixty-three fatal falls were identified, accounting for 15% of all fatal events...
April 28, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28448451/time-aware-service-ranking-prediction-in-the-internet-of-things-environment
#18
Yuze Huang, Jiwei Huang, Bo Cheng, Shuqing He, Junliang Chen
With the rapid development of the Internet of things (IoT), building IoT systems with high quality of service (QoS) has become an urgent requirement in both academia and industry. During the procedures of building IoT systems, QoS-aware service selection is an important concern, which requires the ranking of a set of functionally similar services according to their QoS values. In reality, however, it is quite expensive and even impractical to evaluate all geographically-dispersed IoT services at a single client to obtain such a ranking...
April 27, 2017: Sensors
https://www.readbyqxmd.com/read/28448168/management-of-textile-wastewater-for-improving-growth-and-yield-of-field-mustard-brassica-campestris-l
#19
Muhammad Yaseen, Muhammad Zahir Aziz, Aqleema Komal, Muhammad Naveed
Disposal of industrial wastewater is a current issue of urbanization. However, this problem can be sorted by using wastewater as alternate source of irrigation after the addition of some amendment. In this way, the problem of disposal of wastewater not only will be resolved but also scarcity of irrigation water can be kept off in future. Current research study was performed to evaluate the influence of different concentration of wastewater along with canal water for enhancing growth and yield of field mustard...
April 27, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28448065/construction-of-a-map-based-reference-genome-sequence-for-barley-hordeum-vulgare-l
#20
Sebastian Beier, Axel Himmelbach, Christian Colmsee, Xiao-Qi Zhang, Roberto A Barrero, Qisen Zhang, Lin Li, Micha Bayer, Daniel Bolser, Stefan Taudien, Marco Groth, Marius Felder, Alex Hastie, Hana Šimková, Helena Staňková, Jan Vrána, Saki Chan, María Muñoz-Amatriaín, Rachid Ounit, Steve Wanamaker, Thomas Schmutzer, Lala Aliyeva-Schnorr, Stefano Grasso, Jaakko Tanskanen, Dharanya Sampath, Darren Heavens, Sujie Cao, Brett Chapman, Fei Dai, Yong Han, Hua Li, Xuan Li, Chongyun Lin, John K McCooke, Cong Tan, Songbo Wang, Shuya Yin, Gaofeng Zhou, Jesse A Poland, Matthew I Bellgard, Andreas Houben, Jaroslav Doležel, Sarah Ayling, Stefano Lonardi, Peter Langridge, Gary J Muehlbauer, Paul Kersey, Matthew D Clark, Mario Caccamo, Alan H Schulman, Matthias Platzer, Timothy J Close, Mats Hansson, Guoping Zhang, Ilka Braumann, Chengdao Li, Robbie Waugh, Uwe Scholz, Nils Stein, Martin Mascher
Barley (Hordeum vulgare L.) is a cereal grass mainly used as animal fodder and raw material for the malting industry. The map-based reference genome sequence of barley cv. 'Morex' was constructed by the International Barley Genome Sequencing Consortium (IBSC) using hierarchical shotgun sequencing. Here, we report the experimental and computational procedures to (i) sequence and assemble more than 80,000 bacterial artificial chromosome (BAC) clones along the minimum tiling path of a genome-wide physical map, (ii) find and validate overlaps between adjacent BACs, (iii) construct 4,265 non-redundant sequence scaffolds representing clusters of overlapping BACs, and (iv) order and orient these BAC clusters along the seven barley chromosomes using positional information provided by dense genetic maps, an optical map and chromosome conformation capture sequencing (Hi-C)...
April 27, 2017: Scientific Data
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